OOIR: Observatory of International Research

Papers

(The TQCC of Cell Calcium is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Regulating calcium flux through AMPA glutamate receptors	76
Commentary on: Li et al.; Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds. Nature Communications (2024)	65
Store-operated ion channels: A growing family ?	60
Arriving at the next level of complexity in IP3R and SOCE signaling	59
Rapid quantification of intracellular calcium stores reveals effects of membrane micropeptides on SERCA function	51
Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using an In vitro Platform for Improving Insulin Therapy	50
ER calcium stores contribute to glucose-induced Ca2+ waves and intercellular connectivity in mouse pancreatic islets	39
Protein diversity in store-operated calcium entry components and their related variants	37
TRPM7 in neurodevelopment and therapeutic prospects for neurodegenerative disease	36
Editorial Board	35
The IP3 receptor-KRAP complex at the desmosomes: A new player in the apoptotic process	34
Dyclonine inhibition of TRPV3: From functional discovery to structural insight	30
Abnormal calcium activity and CREB phosphorylation are associated with motor memory impairment in presenilin-1 mutant knock-in mice	30
STIM1: A new player in nuclear dynamics? Lessons learnt from tubular aggregate myopathy	29
A role for lysosomal calcium channels in mitigating mitochondrial damage and oxidative stress	27
MICU1 and MICU2, two peas in a pod or entirely different fruits?	27
TRPC3 governs the spatiotemporal organization of cellular Ca2+ signatures by functional coupling to IP3 receptors	24
Macrophage migration inhibitory factor induces phospholamban phosphorylation in cardiac muscle	23
Calcium signals as regulators of ferroptosis in cancer	23
Ca2+/calmodulin-driven functions mediated by extracellular vesicles: a physiopathological perspective	23
Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on “Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations”	22
Role of auditory-somatosensory corticothalamic circuit integration in analgesia	22
PIP2 primes IP3 receptor activity: It takes at least three IP3s to open!	21
Editorial Board	21
Histamine 1 receptors and reverse-mode Na+/Ca2+ exchanger drive extracellular Na+-dependent intracellular Ca2+ oscillations in human cerebrovascular endothelial cells	21

STIMulating IRE1: How store-operated Ca2+ entry intersects with ER proteostasis	21
Optical profiling of autonomous Ca2+ nanodomains generated by lysosomal TPC2 and TRPML1	21
NAADP-mediated calcium release promotes angiopoietin 2 secretion by regulating Rab46-dependent Weibel-Palade body trafficking	20
Editorial Board	20
Neuronal regulation of myenteric interstitial cells of Cajal (ICC-MY) in the proximal colon	20
Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells	19
Editorial Board	19
Editorial Board	19
High resolution cryo-EM structures of TRPC5-Gαi3 complexes reveal direct activation of an ion channel by Gαi-GTP	19
The tether function of the anoctamins	18
Editorial Board	18
IP3 receptors: An “elementary” journey from structure to signals	18
Endolysosomal calcium release and cardiac physiology	18
Intersection between calcium signalling and epithelial-mesenchymal plasticity in the context of cancer	18
The role of SERCA in vascular diseases, a potential therapeutic target	17
TRPV1 signaling in skeletal muscle: A mini review of physiological and pathological roles	17
Editorial Board	16
The PHATE of basal epidermal cells: Calcium signaling during the cell cycle	15
The emerging role of TRPV4 in skeletal biology: Mechanotransduction, mutation, and therapeutic potential	15
Endoplasmic reticulum-mitochondria lockdown in Wolfram syndrome	15
GPCR signalling: Yet another variant route in a highly complex road map	15
Simultaneous TIRF imaging of subplasmalemmal Ca2+ dynamics and granule fusions in insulin-secreting INS-1 cells reveals coexistent synchronized and asynchronous release	15
Transcriptional, biochemical, and immunohistochemical analyses of CaMKKβ/2 splice variants that co-localize with CaMKIV in spermatids	14
Editorial Board	14
STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39	14
Editorial Board	13
Editorial Board	13
Editorial Board	13
STIM1: The lord of the rings?	12
High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors	12
Calcium signaling and genetic rare diseases: An auditory perspective	12
Barriers to exocytotic vesicle discharge	12
The evolution of organellar calcium mapping technologies	12
Neuronal and astrocyte NCX isoform/splice variants: How do they participate in Na+ and Ca2+ signalling?	12
Regulation of the regulator: Endopeptidase cleavage controls the expression of a micropeptide that regulates SERCA.	12
CPVT1 point mutations in RyR2 S5 and S6 segments and their Ca2+ signaling consequence	11
A NOX2-independent mechanism of Hv1 channel activation promotes inflammatory cytokine release from BV-2 microglia via intracellular Ca2+ mobilisation	11
Orai1 mediates ICRAC and SOCE in human placental extravillous trophoblasts and contributes to cell viability, migration, and invasion	11
TRPV2 inhibitor tranilast prevents atrial fibrillation in rat models of pulmonary hypertension	10
ELD607 specifically traffics Orai1 to the lysosome leading to inhibition of store operated calcium entry	10
Calcium influx into astrocytes plays a pivotal role in inflammation-driven behaviors	10
Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on “Structural insights into the regulation of RyR1 by S100A1”	10
Changing of the guards while steering a familiar course	10
Structural snapshots of the mechanism of TRPV2 channel activation by small-molecule agonists	10
Editorial Board	10
Ablation of mitochondrial calcium uniporter alleviates cardiac dysfunction in type 1 diabetes	10
Calcium signalling in hepatic metabolism: Health and diseases	10
Regulation of K+-dependent Na+/Ca2+-exchanger subtype 4, NCKX4, by palmitoylation	9
Distinct pools of synaptic vesicles are released by different calcium channels	9
Multi-neurotransmitter regulation of neural firing via coincidence of parallel G-protein signals	9

Pan-cancer analysis reveals the prognostic gene CASR suppresses tumor progression and epithelial–mesenchymal transition in renal clear cell carcinoma	9
Channeling hope for uranium-induced kidney damage and beyond with TRPML1	9
Connexin 43 as a novel Ca2+ transport pathway in the nuclear envelope of human induced pluripotent stem cell derived cardiomyocytes	9
Copine A is essential for calcium homeostasis in Dictyostelium	9
Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7	9
Toll-like receptor 4 activation enhances Orai1-mediated calcium signal promoting cytokine production in spinal astrocytes.	9
Scaling up neuronal Ca2+, signaling on ER ladders	9
Transglutaminase 2 controls calcium dependent mitochondrial dysfunction and fibroblast senescence by repressing PIEZO2	9
Inhibition of TRPV1 by an antagonist in clinical trials is dependent on cholesterol binding	9
Calcium and chloride out of sync: The role of signaling in Sjögren's salivary gland issues	9
Altered composition of the mitochondrial Ca2+uniporter in the failing human heart	9
In memoriam: Irene Schulz 1941 – 2026	8
SERCA2 phosphorylation at the heart of the disease	8
Editorial Board	8
Orai1/STIMs modulators in pulmonary vascular diseases	8
Engulf and digest – TRPM7 as key regulator of macrophage phagosome maturation	8
LETM1 and mitochondrial calcium homeostasis: A controversial but critical role in cellular function and disease	8