OOIR: Observatory of International Research

Papers

(The TQCC of Cell Calcium is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Mitochondria Associated Membranes (MAMs): Architecture and physiopathological role	80
Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels	77
Role of mitochondria in liver metabolic health and diseases	69
VDAC regulation of mitochondrial calcium flux: From channel biophysics to disease	62
Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration	58
The aging mouse brain: cognition, connectivity and calcium	51
Piezo1 impairs hepatocellular tumor growth via deregulation of the MAPK-mediated YAP signaling pathway	47
Mitochondrial reactive oxygen species in physiology and disease	46
Mechanosensitive Piezo1 in endothelial cells promotes angiogenesis to support bone fracture repair	39
Human TRPA1 is an inherently mechanosensitive bilayer-gated ion channel	39
Role of ion channels during cell division	37
Heterogeneous expression of plasma-membrane-localised OsOSCA1.4 complements osmotic sensing based on hyperosmolality and salt stress in Arabidopsis osca1 mutant	32
The molecular complexity of the Mitochondrial Calcium Uniporter	32
IP3 receptor-mediated Ca2+ release from acidocalcisomes regulates mitochondrial bioenergetics and prevents autophagy in Trypanosoma cruzi	31
α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport	31
Ca2+ as the prime trigger of aerobic glycolysis in astrocytes	28
BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening	27
Mitochondrial dysfunction in neurodegenerative diseases: A focus on iPSC-derived neuronal models	26
Cimifugin relieves pruritus in psoriasis by inhibiting TRPV4	26
Lysosomal ion channels involved in cellular entry and uncoating of enveloped viruses: Implications for therapeutic strategies against SARS-CoV-2	26
Role of TRPM7 kinase in cancer	25
Two-photon calcium imaging of seizures in awake, head-fixed mice	24
NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain microvascular endothelial cells	24
The role of potassium and host calcium signaling in Toxoplasma gondii egress	23
Skeletal muscle mitochondria in health and disease	22

Conjugated polymers mediate intracellular Ca2+ signals in circulating endothelial colony forming cells through the reactive oxygen species-dependent activation of Transient Receptor Potential Vanilloi	21
Regulation and role of calcium in cellular senescence	21
Altered composition of the mitochondrial Ca2+uniporter in the failing human heart	20
The calcium signaling enzyme CD38 - a paradigm for membrane topology defining distinct protein functions	20
ANO1 regulates cardiac fibrosis via ATI-mediated MAPK pathway	20
Control of STIM and Orai function by post-translational modifications	19
ZnT1 is a neuronal Zn2+/Ca2+ exchanger	19
Calcium signaling and epigenetics: A key point to understand carcinogenesis	19
The ER-mitochondria interface, where Ca2+ and cell death meet	19
The bitter end: T2R bitter receptor agonists elevate nuclear calcium and induce apoptosis in non-ciliated airway epithelial cells	19
Ca2+ signaling and cell death	18
Andrographolide ameliorates aortic valve calcification by regulation of lipid biosynthesis and glycerolipid metabolism targeting MGLL expression in vitro and in vivo	18
The mitochondrial permeability transition pore in Ca2+ homeostasis	18
Recent studies on NCLX in health and diseases	18
AHNAK: The quiet giant in calcium homeostasis	18
Ca2+ transients in ICC-MY define the basis for the dominance of the corpus in gastric pacemaking	18
Modulating TRPV4 channels with paclitaxel and lithium	17
Vesicle cholesterol controls exocytotic fusion pore	17
TRPV4 and TRPC1 channels mediate the response to tensile strain in mouse Müller cells	17
Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties	17
PUFAs dictate the balance of power in ferroptosis	17
TRPMLs and TPCs: Targets for lysosomal storage and neurodegenerative disease therapy?	16
Control by Ca2+ of mitochondrial structure and function in pancreatic β-cells	16
PIP2 and septin control STIM1/Orai1 assembly by regulating cytoskeletal remodeling via a CDC42-WASP/WAVE-ARP2/3 protein complex	15
Calcium signaling: A therapeutic target to overcome resistance to therapies in cancer	15
Enhanced modulation of cell-type specific neuronal responses in mouse dorsal auditory field during locomotion	15
The great astroglial metabolic revolution: Mitochondria fuel astrocyte homeostatic support and neuroprotection	15
The yin and yang of mitochondrial Ca2+ signaling in cell physiology and pathology	15
Role of STIM2 and Orai proteins in regulating TRPC1 channel activity upon calcium store depletion	15
Metabolite regulation of the mitochondrial calcium uniporter channel	15
Activation of endo-lysosomal two-pore channels by NAADP and PI(3,5)P2. Five things to know.	15
Distinct properties of Ca2+ efflux from brain, heart and liver mitochondria: The effects of Na+, Li+ and the mitochondrial Na+/Ca2+ exchange inhibitor CGP37157	15
Inhibition of TRPM7 with waixenicin A reduces glioblastoma cellular functions	14
A high throughput machine-learning driven analysis of Ca2+ spatio-temporal maps	14
A novel role of FKN/CX3CR1 in promoting osteogenic transformation of VSMCs and atherosclerotic calcification	14
Insights into the molecular basis of the palmitoylation and depalmitoylation of NCX1	13
Attenuation of the extracellular matrix increases the number of synapses but suppresses synaptic plasticity through upregulation of SK channels	13
The basics of mitochondrial cAMP signalling: Where, when, why	13
Cristae junction as a fundamental switchboard for mitochondrial ion signaling and bioenergetics	13
Mitochondria as the decision makers for cancer cell fate: from signaling pathways to therapeutic strategies	13
NCX1 and EAAC1 transporters are involved in the protective action of glutamate in an in vitro Alzheimer's disease-like model	13
Acidic Ca2+ stores and immune-cell function	13
The evolution of organellar calcium mapping technologies	12
Homeostatic calcium fluxes, ER calcium release, SOCE, and calcium oscillations in cultured astrocytes are interlinked by a small calcium toolkit	12
STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39	12
Specific cytokines of interleukin-6 family interact with S100 proteins	12
Na+/Ca2+ exchanger isoform 1 (NCX1) and canonical transient receptor potential channel 6 (TRPC6) are recruited by STIM1 to mediate Store-Operated Calcium Entry in primary cortical neurons	12
SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer	11
Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7	11
Structural biology of cation channels important for lysosomal calcium release	11

Lysosomal potassium channels	11
Calcium signaling in lysosome-dependent cell death	10
Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7	10
Insulin-like growth factor-1 regulates the mechanosensitivity of chondrocytes by modulating TRPV4	10
Ca2+ signaling in postsynaptic neurons: Neuroplastin-65 regulates the interplay between plasma membrane Ca2+ ATPases and ionotropic glutamate receptors	10
Understanding IP3R channels: From structural underpinnings to ligand-dependent conformational landscape	10
Differential modulation of SK channel subtypes by phosphorylation	10
Sprinkling salt on mitochondria: The metabolic and pathophysiological roles of mitochondrial Na+ signaling mediated by NCLX	10
Potential of targeting host cell calcium dynamics to curtail SARS-CoV-2 infection and COVID-19 pathogenesis	10
Loss of PKD1 and PKD2 share common effects on intracellular Ca2+ signaling	9
Pannexin 1 plays a pro-survival role by attenuating P2X7 receptor-mediated Ca2+ influx	9
Modulators of TRPM7 and its potential as a drug target for brain tumours	9
Multi-scale network imaging in a mouse model of amyloidosis	9
In vivo analysis of the spontaneous firing of cerebellar Purkinje cells in awake transgenic mice that model spinocerebellar ataxia type 2	9
TRPV1: Receptor structure, activation, modulation and role in neuro-immune interactions and pain	9
TRPV3 endogenously expressed in murine colonic epithelial cells is inhibited by the novel TRPV3 blocker 26E01	9
TRPC1 channels regulate the activation of pancreatic stellate cells through ERK1/2 and SMAD2 pathways and perpetuate their pressure-mediated activation	9
Exploring the Li+ transporting mutant of NCX_Mj for assigning ion binding sites of mitochondrial NCLX	9
Differential expression of the three independent CaM genes coding for an identical protein: Potential relevance of distinct mRNA stability by different codon usage	9
CatSper channels in sea urchin sperm	9
Postnatal maturation of calcium signaling in islets of Langerhans from neonatal mice	9
CaMKIV regulates mitochondrial dynamics during sepsis	9
Neurophysiological functions and pharmacological tools of acidic and non-acidic Ca2+ stores	9
TRPC3 governs the spatiotemporal organization of cellular Ca2+ signatures by functional coupling to IP3 receptors	9
Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume	9
The expression of constitutively active CPK3 impairs potassium uptake and transport in Arabidopsis under low K+ stress	9
KRAP is required for diffuse and punctate IP3-mediated Ca2+ liberation and determines the number of functional IP3R channels within clusters	9
Spontaneous and action potential-evoked Ca2+ release from endoplasmic reticulum in neocortical synaptic boutons	8
Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells	8
The dynamic nature of exocytosis from large secretory vesicles. A view from electrochemistry and imaging	8
Vascular Kv7 channels control intracellular Ca2+ dynamics in smooth muscle	8
Relevance of lysosomal Ca2+ signalling machinery in cancer	8
LIPID transfer proteins regulate store-operated calcium entry via control of plasma membrane phosphoinositides	8
VDAC2 as a novel target for heart failure: Ca2+ at the sarcomere, mitochondria and SR	8
Glucose-induced [Ca2+]i oscillations in β cells are composed of trains of spikes within a subplasmalemmal microdomain	8
Mutations and clinical significance of calcium voltage-gated channel subunit alpha 1E (CACNA1E) in non-small cell lung cancer	8
Ryanodine receptor-mediated Ca2+ release and atlastin-2 GTPase activity contribute to IP3-induced dendritic Ca2+ signals in primary hippocampal neurons	8
Too much of a good thing: The case of SOCE in cellular apoptosis	8
Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts	8
Calcium signaling in polycystic kidney disease- cell death and survival	8
The TAM-associated STIM1I484R mutation increases ORAI1 channel function due to a reduced STIM1 inactivation break and an absence of microtubule trapping	8
Full-fusion and kiss-and-run in chromaffin cells controlled by irreversible vesicle size-dependent fusion pore transitions	8
The ins and outs of virus trafficking through acidic Ca2+ stores	8
Isoproterenol-induced hypertrophy of neonatal cardiac myocytes and H9c2 cell is dependent on TRPC3-regulated CaV1.2 expression	8
Injury-induced Erk1/2 signaling tissue-specifically interacts with Ca2+ activity and is necessary for regeneration of spinal cord and skeletal muscle	7
CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer	7
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release	7
Dopamine controls neuronal spontaneous calcium oscillations via astrocytic signal	7
ZnR/GPR39 controls cell migration by orchestrating recruitment of KCC3 into protrusions, re-organization of actin and activation of MMP	7
Role of auditory-somatosensory corticothalamic circuit integration in analgesia	7
Dual function of the choroid plexus: Cerebrospinal fluid production and control of brain ion homeostasis	7
Toll-like receptor 4 activation enhances Orai1-mediated calcium signal promoting cytokine production in spinal astrocytes.	7
Targeted Gq-GPCR activation drives ER-dependent calcium oscillations in chondrocytes	7
p53 alters intracellular Ca2+ signaling through regulation of TRPM4	7
The unfolding and activation of STIM1 in store-operated calcium signal generation	7
The mitochondrial sodium/calcium exchanger NCLX (Slc8b1) in B lymphocytes	7
The role of Ca2+ signalling in the pathology of exocrine pancreas	7
Regulation of the tubulin polymerization-promoting protein by Ca2+/S100 proteins	7
Interplay between calcium and endoplasmic reticulum stress	7
High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors	7
A TRPV6 expression atlas for the mouse	7
JPT2: The missing link between intracellular Ca2+ release channels and NAADP?	7
Channelopathy-causing mutations in the S45A/S45B and HA/HB helices of KCa2.3 and KCa3.1 channels alter their apparent Ca2+ sensitivity	7
Calcium as a master regulator of ferroptosis and other types of regulated necrosis	7
Ca2+ signalling system initiated by endoplasmic reticulum stress stimulates PERK activation	7