Placenta

Article	Citations
A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection	163
Consistent localization of SARS-CoV-2 spike glycoprotein and ACE2 over TMPRSS2 predominance in placental villi of 15 COVID-19 positive maternal-fetal dyads	107
The placenta in fetal growth restriction: What is going wrong?	106
SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19	97
Placental barrier against COVID-19	69
Trophoblast invasion: Lessons from abnormally invasive placenta (placenta accreta)	62
Placental lesions and SARS-Cov-2 infection: Diffuse placenta damage associated to poor fetal outcome	52
Review: Histotrophic nutrition and the placental-endometrial dialogue during human early pregnancy	47
Syncytins expressed in human placental trophoblast	43
Review of MRI imaging for placenta accreta spectrum: Pathophysiologic insights, imaging signs, and recent developments	43
Meta-analysis on COVID-19-pregnancy-related placental pathologies shows no specific pattern	42
Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome	42
Trophoblast lineage-specific differentiation and associated alterations in preeclampsia and fetal growth restriction	41
Maternal stress, placental 11β-hydroxysteroid dehydrogenase type 2, and infant HPA axis development in humans: Psychosocial and physiological pathways	39
Upregulation of METTL3 expression and m6A RNA methylation in placental trophoblasts in preeclampsia	38
Placental macrophages: Origin, heterogeneity, function and role in pregnancy-associated infections	36
Exploring the causes and consequences of maternal metabolic maladaptations during pregnancy: Lessons from animal models	34
PGE2 vs PGF2α in human parturition	34
Placental pathology in COVID-19 affected pregnant women: A prospective case-control study	33
Update review on five top clinical applications of human amniotic membrane in regenerative medicine	32
Placental structural abnormalities in gestational diabetes and when they develop: A scoping review	31
Human implantation: The complex interplay between endometrial receptivity, inflammation, and the microbiome	31
The role of obesity and gestational diabetes on placental size and fetal oxygenation	30
A crossroad between placental and tumor biology: What have we learnt?	30
Abnormalities of placental development and function are associated with the different fetal growth patterns of hypoplastic left heart syndrome and transposition of the great arteries	29

Novel approaches to combat preeclampsia: from new drugs to innovative delivery	29
First trimester biomarkers for prediction of gestational diabetes mellitus	29
Factors preventing materno-fetal transmission of SARS-CoV-2	28
Placental miRNAs in feto-maternal communication mediated by extracellular vesicles	28
Potential SARS-CoV-2 interactions with proteins involved in trophoblast functions – An in-silico study	27
Placental small extracellular vesicles: Current questions and investigative opportunities	27
Differences in cytochrome p450 enzyme expression and activity in fetal and adult tissues	27
Research on nanoparticles in human perfused placenta: State of the art and perspectives	27
Decreased maternal serum adiponectin and increased insulin-like growth factor-1 levels along with increased placental glucose transporter-1 expression in gestational diabetes mellitus: Possible role i	26
PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis	26
Maternal interventions to prevent adverse fetal programming outcomes due to maternal malnutrition: Evidence in animal models	26
Molecular characteristics of established trophoblast-derived cell lines	25
Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studies	25
Ultrasound-histopathologic features of the utero-placental interface in placenta accreta spectrum	24
CircSFXN1 regulates the behaviour of trophoblasts and likely mediates preeclampsia	24
Placental mitochondrial function in response to gestational exposures	24
MiR-124–3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor	23
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network	23
Fetal exposure to environmental chemicals; insights from placental perfusion studies	22
Extracellular vesicles as critical mediators of maternal-fetal communication during pregnancy and their potential role in maternal metabolism	22
Umbilical cord plasma-derived exosomes from preeclamptic women induce vascular dysfunction by targeting HMGCS1 in endothelial cells	22
Placental syncytiotrophoblast extracellular vesicles enter primary endothelial cells through clathrin-mediated endocytosis	22
Derivation of endometrial gland organoids from term placenta	21
Investigating the risk of maternal-fetal transmission of SARS-CoV-2 in early pregnancy	21
CircLRRK1 targets miR-223-3p to inhibit the proliferation, migration and invasion of trophoblast cells by regulating the PI3K/AKT signaling pathway	21
Anti-inflammatory effects of phenolic acids punicalagin and curcumin in human placenta and adipose tissue	21
The use of elastography in placental research – A literature review	21
Paradigms for investigating invasive trophoblast cell development and contributions to uterine spiral artery remodeling	20
Commentary on a combined approach to the problem of developing biomarkers for the prediction of spontaneous preterm labor that leads to preterm birth	20
SIRT1 regulates trophoblast senescence in premature placental aging in preeclampsia	20
T2* placental MRI in pregnancies complicated with fetal congenital heart disease	20
Structural changes to the brood pouch of male pregnant seahorses (Hippocampus abdominalis) facilitate exchange between father and embryos	19
PFKFB3 regulates lipopolysaccharide-induced excessive inflammation and cellular dysfunction in HTR-8/Svneo cells: Implications for the role of PFKFB3 in preeclampsia	19
3-Dimensional JEG-3 choriocarcinoma cell organoids as a model for trophoblast expansion and differentiation	19
Stretch, scratch, and stress: Suppressors and supporters of senescence in human fetal membranes	19
Circ_0085296 suppresses trophoblast cell proliferation, invasion, and migration via modulating miR-144/E-cadherin axis	18
Pandemic stress and SARS-CoV-2 infection are associated with pathological changes at the maternal-fetal interface	18
New endometrial immune cell-based score (EI-score) for the prediction of implantation success for patients undergoing IVF/ICSI	18
The role of β-HCG and VEGF-MEK/ERK signaling pathway in villi angiogenesis in patients with missed abortion	18
Quercetin improved histological structure and upregulated adiponectin and adiponectin receptors in the placenta of rats with gestational diabetes mellitus	18
Heme oxygenase-1 gene modified human placental mesenchymal stem cells promote placental angiogenesis and spiral artery remodeling by improving the balance of angiogenic factors in vitro	18
Adaptive responses to maternal nutrient restriction alter placental transport in ewes	18
miR-15b-5p promotes expression of proinflammatory cytokines in human placenta by inhibiting Apelin signaling pathway	18
The risk factors associated with placenta previa: An umbrella review	17
Differentially expressed circular RNAs and the competing endogenous RNA network associated with preeclampsia	17
Placental deficiency during maternal SARS-CoV-2 infection	17
Oxidative stress biomarkers in fetal growth restriction with and without preeclampsia	17
Air pollution and pre-eclampsia; associations and potential mechanisms	17
ELABELA alleviates syncytiotrophoblast hypoxia/reoxygenation injury and preeclampsia-like symptoms in mice by reducing apoptosis	17
Multiscale three-dimensional imaging of the placenta	17

Maternal stress in relation to sex-specific expression of placental genes involved in nutrient transport, oxygen tension, immune response, and the glucocorticoid barrier	17
Maternal risk factors associated with persistent placenta previa	16
Placental weight centiles adjusted for age, parity and fetal sex	16
Endocytosis in the placenta: An undervalued mediator of placental transfer	16
Cyclosporin A alleviates trophoblast apoptosis and senescence by promoting autophagy in preeclampsia	16
Maternal oxycodone treatment causes pathophysiological changes in the mouse placenta	16
The role of maternal–foetal interface inflammation mediated by NLRP3 inflammasome in the pathogenesis of recurrent spontaneous abortion	16
Maternal altitude and risk of low birthweight: A systematic review and meta-analyses	16
Serum miRNA biomarker discovery for placenta accreta spectrum	16
Transient loss of endothelial cells in human spiral artery remodelling during early pregnancy: Challenging the dogma	16
The placental pathology in Coronavirus disease 2019 infected mothers and its impact on pregnancy outcome	16
Placental hypoxia: What have we learnt from small animal models?	15
Placental magnetic resonance imaging in chronic hypertension: A case-control study	15
Second trimester uterine arteries pulsatility index is a function of placental pathology and provides insights on stillbirth aetiology: A multicenter matched case-control study	15
Clinical factors associated with a placenta accreta spectrum	15
microRNA-210/ Long non-coding RNA MEG3 axis inhibits trophoblast cell migration and invasion by suppressing EMT process	15
MiR-193b inhibits autophagy and apoptosis by targeting IGFBP5 in high glucose-induced trophoblasts	15
Placental blood flow sensing and regulation in fetal growth restriction	15
Transgenic expression of human C19MC miRNAs impacts placental morphogenesis	15
Third trimester stillbirth during the first wave of the SARS-CoV-2 pandemic: Similar rates with increase in placental vasculopathic pathology	15
Brain and placental transcriptional responses as a readout of maternal and paternal preconception stress are fetal sex specific	14
Preeclampsia: inflammatory signature of decidual cells in early manifestation of disease	14
High altitude regulates the expression of AMPK pathways in human placenta	14
The clinical impact of maternal COVID-19 on mothers, their infants, and placentas with an analysis of vertical transfer of maternal SARS-CoV-2-specific IgG antibodies	14
Histomorphological changes of the placenta and umbilical cord in pregnancies complicated by gestational diabetes mellitus	14
Syncytiotrophoblast stress in early onset preeclampsia: The issues perpetuating the syndrome	14
Maternal, fetal and placental regulation of placental iron trafficking	14
Oxidative stress markers in preeclamptic placentas: A systematic review with meta-analysis	14
Low-level SARS-CoV-2 viremia coincident with COVID placentitis and stillbirth	14
Sulforaphane improves vascular reactivity in mouse and human arteries after “preeclamptic-like” injury	14
Isolation and characterization human chorion membrane trophoblast and mesenchymal cells	14
MiR-135a-5p promotes the migration and invasion of trophoblast cells in preeclampsia by targeting β-TrCP	14
Pericytes on placental capillaries in terminal villi preferentially cover endothelial junctions in regions furthest away from the trophoblast	14
Gestational trophoblastic neoplasia: Novelties and challenges	14
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway	14
Understanding the uterine artery Doppler waveform and its relationship to spiral artery remodelling	14
Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition	14
Iodothyronine deiodinase 2 (DiO2) regulates trophoblast cell line cycle, invasion and apoptosis; and its downregulation is associated with early recurrent miscarriage	14
Telomere erosion as a placental clock: From placental pathologies to adverse pregnancy outcomes	14
Identification and validation of DNA methylation changes in pre-eclampsia	13
Circ-AK2 is associated with preeclampsia and regulates biological behaviors of trophoblast cells through miR-454–3p/THBS2	13
Hypoxic effects on the mitochondrial content and functions of the placenta in fetal growth restriction	13
Neutrophils in preterm birth: Friend or foe?	13
Lactobacillus crispatus promotes invasion of the HTR-8/SVneo trophoblast cell line	13
The metabolic landscape of decidua in recurrent pregnancy loss using a global metabolomics approach	13
Maternal obesity increases the risk of fetal cardiac dysfunction via visceral adipose tissue derived exosomes	13
Aberrantly up-regulated miR-142-3p inhibited the proliferation and invasion of trophoblast cells by regulating FOXM1	13
The placental programming hypothesis: Placental endocrine insufficiency and the co-occurrence of low birth weight and maternal mood disorders	13
Evaluation of vertical transmission of SARS-CoV-2 in utero: Nine pregnant women and their newborns	13
Impact of World War 1 on placenta weight, birth weight and other anthropometric parameters of neonatal health	13
Upregulation of METTL14 contributes to trophoblast dysfunction by elevating FOXO3a expression in an m6A-dependent manner	13
Dysregulated miRNAs contribute to altered placental glucose metabolism in patients with gestational diabetes via targeting GLUT1 and HK2	13
Sex matters: XIST and DDX3Y gene expression as a tool to determine fetal sex in human first trimester placenta	13
Sulforaphane improves syncytiotrophoblast mitochondrial function after in vitro hypoxic and superoxide injury	13
Extracellular vesicles and their role in gestational diabetes mellitus	13
The effects of exercise during pregnancy on placental composition: A systematic review and meta-analysis	13
Know the game: Insights to help early career researchers successfully navigate academia	12
Placental apoptotic markers are associated with placental morphometry	12
Diminished trophoblast differentiation in early onset preeclampsia	12
Polymorphisms of hypertension susceptibility genes as a risk factors of preeclampsia in the Caucasian population of central Russia	12
Current understanding of autophagy in intrahepatic cholestasis of pregnancy	12
The road (not) taken – Placental transfer and interspecies differences	12
Perfusion fraction derived from IVIM analysis of diffusion-weighted MRI in the assessment of placental vascular malperfusion antenatally	12
Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth	12
Maternal, placental, and fetal distribution of titanium after repeated titanium dioxide nanoparticle inhalation through pregnancy	12
Paternal low protein diet and the supplementation of methyl-donors impact fetal growth and placental development in mice	12
SIRT3 deficiency affects the migration, invasion, tube formation and necroptosis of trophoblast and is implicated in the pathogenesis of preeclampsia	12
The challenge of using nanotherapy during pregnancy: Technological aspects and biomedical implications	12
Placenta morphology and biomarkers in pregnancies with congenital heart disease – A systematic review	12
Chronic villitis of unknown etiology: Investigations into viral pathogenesis	12
Placental dysfunction: The core mechanism for poor neurodevelopmental outcomes in the offspring of preeclampsia pregnancies	12
Understanding decidual vasculopathy and the link to preeclampsia: A review	12
Doppler studies of placental function	12
Diagnostic capacity of sFlt-1/PlGF ratio in fetal growth restriction: A systematic review and meta-analysis	12
Prenatal interventions for fetal growth restriction in animal models: A systematic review	11
FGF15/FGF19 alleviates insulin resistance and upregulates placental IRS1/GLUT expression in pregnant mice fed a high-fat diet	11
Amniotic fluid stem cells as a novel strategy for the treatment of fetal and neonatal neurological diseases	11
Placental distribution of endogenous and exogenous substances: A pilot study utilizing cryo-sampled specimen off delivery room	11
Molar pregnancy in the last 50 years: A bibliometric analysis of global research output	11
Effect and mechanism of prophylactic use of tadalafil during pregnancy on l-NAME-induced preeclampsia-like rats	11

Brood pouch evolution in pipefish and seahorse based on histological observation	11
Magnetic resonance imaging of placentome development in the pregnant Ewe	11
Prediction of hypertension in pregnancy in high risk women using maternal factors and serial placental profile in second and third trimester	11
Placental MRI: Development of an MRI compatible ex vivo system for whole placenta dual perfusion	11
First trimester serum PIGF is associated with placenta accreta	11
Platelet alloimmunization is associated with low grade chronic histiocytic intervillositis - A new link to a rare placental lesion?	11
Chronic Intervillositis of Unknown Etiology (CIUE): Prevalence, patterns and reproductive outcomes at a tertiary referral institution	11
MRI based morphological examination of the placenta	11
Visualizing ultrastructural details of placental tissue with super-resolution structured illumination microscopy	11
Impact of location on placentation in live tubal and cesarean scar ectopic pregnancies	11
Trimethylamine N-Oxide increases soluble fms-like tyrosine Kinase-1 in human placenta via NADPH oxidase dependent ROS accumulation	11
Comparative study of placental T2* and intravoxel incoherent motion in the prediction of fetal growth restriction	11
Extracellular vesicles- crucial players in human pregnancy	11
Stomatin-like protein 2 (SLP2) regulates the proliferation and invasion of trophoblast cells by modulating mitochondrial functions	11
Integrated analysis of multiple microarray studies to identify novel gene signatures in preeclampsia	10
Associations between AGT, MTHFR, and VEGF gene polymorphisms and preeclampsia in the Chinese population	10
The singular case of multiple chorangioma syndrome in an IVF pregnancy. Analysis of the case and review of literature	10
Maternal platelets at the first trimester maternal-placental interface – Small players with great impact on placenta development	10
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia	10
miR-486-5p inhibits invasion and migration of HTR8/SVneo trophoblast cells by down-regulating ARHGAP5	10
The abnormal expression of Tim-3 is involved in the regulation of myeloid-derived suppressor cells and its correlation with preeclampsia	10
Influence of culture media on the derivation and phenotype of fetal-derived placental mesenchymal stem/stromal cells across gestation	10
O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes	10
Regulation of trophoblast cell invasion by Pyruvate Kinase isozyme M2 (PKM2)	10
Prevention of preterm birth: Proactive and reactive clinical practice-are we on the right track?	10
Chronic villitis: Refining the risk ratio of recurrence using a large placental pathology sample	10
Folding of the syncytiotrophoblast basal plasma membrane increases the surface area available for exchange in human placenta	10
Massive perivillous fibrin deposition of the placenta and pregnancy outcome: A retrospective observational study	10
Coronavirus disease 2019 and the placenta: A literature review	10
Antiviral properties of placental growth factors: A novel therapeutic approach for COVID-19 treatment	10
From stem cells to spiral arteries: A journey through early placental development	10
Circ_0015382 is associated with preeclampsia and regulates biological behaviors of trophoblast cells through miR-149-5p/TFPI2 axis	10
Placentation and embryo death in the plains viscacha (Lagostomus maximus)	10
The vascular equator in monochorionic twin placentas	10
Elevated placental histone H3K4 methylation via upregulated histone methyltransferases SETD1A and SMYD3 in preeclampsia and its possible involvement in hypoxia-induced pathophysiological process	10
A mouse model of placenta accreta spectrum	10
Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability	9
Seroprevalence of SARS-CoV-2 immunoglobulins in pregnant women and neonatal cord blood from a highly impacted region	9
AOPPs induce HTR-8/SVneo cell apoptosis by downregulating the Nrf-2/ARE/HO-1 anti-oxidative pathway: Potential implications for preeclampsia	9
Connecting the dots on vertical transmission of SARS-CoV-2 using protein-protein interaction network analysis – Potential roles of placental ACE2 and ENDOU	9
TAM and TIM receptors mRNA expression in Zika virus infected placentas	9
A disintegrin and metalloproteinase 12 (ADAM12) is reduced at 36 weeks’ gestation in pregnancies destined to deliver small for gestational age infants	9
The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue	9
The polarized localization of lipoprotein receptors and cholesterol transporters in the syncytiotrophoblast of the placenta is reproducible in a monolayer of primary human trophoblasts	9
The association between vein-to-vein anastomoses and birth weight discordance in relation to placental sharing in monochorionic twin placentas	9
Suppression of human trophoblast syncytialization by human cytomegalovirus infection	9
The (pro)renin receptor (ATP6AP2) does not play a role in syncytialisation of term human primary trophoblast cells	9
Addressing microchimerism in pregnancy by ex vivo human placenta perfusion	9
STAT3 signaling pathway is involved in the pathogenesis of miscarriage	9
Cytogenomics of six human trophoblastic cell lines	9
First-trimester utero-placental (vascular) development and embryonic and fetal growth: The Rotterdam periconception cohort	9
Predictors of adverse neonatal outcome in pregnancies complicated by placenta previa	9
Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies	9
Dynamic contrast enhanced magnetic resonance imaging: A review of its application in the assessment of placental function	9
Epidemiology of placenta accreta spectrum disorders in Chinese pregnant women: A multicenter hospital-based study	9
CircHIPK3 contributes to human villous trophoblast growth, migration and invasion via modulating the pathway of miR-346/KCMF1	9
T2* weighted placental MRI in relation to placental histology and birth weight	9
The m6A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression	9
The association between first trimester placental biomarkers and placental lesions of maternal vascular malperfusion	9
Association between maternal hemoglobin concentration and placental weight to birthweight ratio: The Japan Environment and Children's Study (JECS)	9
Umbilical cord compromise versus other clinical conditions predisposing to placental fetal vascular malperfusion	9
Diagnostic accuracy of fetal growth charts for placenta-related fetal growth restriction	9
Evaluation of oxidative stress markers in subtypes of preeclampsia: A systematic review and meta-analysis	9
Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy	9
Isolated fetal neural tube defects associate with increased risk of placental pathology: Evidence from the Collaborative Perinatal Project	9
Three-dimensional visualisation of the feto-placental vasculature in humans and rodents	9
The diagnostic value of two-dimensional shear wave elastography in gestational diabetes mellitus	9
Maternal thyroid profile in first and second trimester of pregnancy is correlated with gestational diabetes mellitus through machine learning	9
Fatty acids in the placenta of appropiate- versus small-for-gestational-age infants at term birth	8
Global DNA methylation in placental tissues from pregnant with preeclampsia: A systematic review and pathway analysis	8
Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK/ERK 1/2 pathway	8
Severe early-onset PE with or without FGR in Chinese women	8
Placental transport of parabens studied using an ex-vivo human perfusion model	8
Gardnerella vaginalis infection in pregnancy: Effects on placental development and neonatal outcomes	8
Analysis of mitochondrial regulatory transcripts in publicly available datasets with validation in placentae from pre-term, post-term and fetal growth restriction pregnancies	8
Relationship between placental elastography, maternal pre-pregnancy body mass index and gestational weight gain	8
G-CSF: A vehicle for communication between trophoblasts and macrophages which may cause problems in recurrent spontaneous abortion	8
Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia	8
Cleavage of the soluble (pro)renin receptor (sATP6AP2) in the placenta	8
The predictive value of pre-delivery laboratory test results for the severity of placental abruption and pregnancy outcome	8
Establishment and characterization of a new human first trimester Trophoblast cell line, AL07	8
Pulsatility effects of flow on vascular tone in the fetoplacental circulation	8
Recurrence risk of villitis of unknown etiology: Analysis of a large retrospective cohort study, systematic review and meta-analysis	8
Placental vascular tree characterization based on ex-vivo MRI with a potential application for placental insufficiency assessment	8
Challenges in preterm birth research: Ghanaian perspective	8
A simple method to isolate term trophoblasts and maintain them in extended culture	8
Salivary cytokines levels, maternal periodontitis and infants' weight at birth: A cohort study in pregnant women with obesity	8
Exploring the impact of HIV infection and antiretroviral therapy on placenta morphology	8
Uterine damage induces placenta accreta and immune imbalance at the maternal-fetal interface in the mouse	8
Increased placental expression of angiotensin-converting enzyme 2, the receptor of SARS-CoV-2, associated with hypoxia in twin anemia-polycythemia sequence (TAPS)	8
Viviparity in the longest-living vertebrate, the Greenland shark (Somniosus microcephalus)	8
Preeclampsia serum increases CAV1 expression and cell permeability of human renal glomerular endothelial cells via down-regulating miR-199a-5p, miR-199b-5p, miR-204	8
Periconceptional maternal and paternal homocysteine levels and early utero-placental (vascular) growth trajectories: The Rotterdam periconception cohort	8
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy	8
On the use of multicompartment models of diffusion and relaxation for placental imaging	8