Placenta

Article	Citations
A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection	166
SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19	101
Trophoblast invasion: Lessons from abnormally invasive placenta (placenta accreta)	66
Placental lesions and SARS-Cov-2 infection: Diffuse placenta damage associated to poor fetal outcome	54
Syncytins expressed in human placental trophoblast	50
Review: Histotrophic nutrition and the placental-endometrial dialogue during human early pregnancy	50
Ferroptosis, trophoblast lipotoxic damage, and adverse pregnancy outcome	46
Review of MRI imaging for placenta accreta spectrum: Pathophysiologic insights, imaging signs, and recent developments	44
Trophoblast lineage-specific differentiation and associated alterations in preeclampsia and fetal growth restriction	44
Meta-analysis on COVID-19-pregnancy-related placental pathologies shows no specific pattern	43
Upregulation of METTL3 expression and m6A RNA methylation in placental trophoblasts in preeclampsia	41
PGE2 vs PGF2α in human parturition	40
Human implantation: The complex interplay between endometrial receptivity, inflammation, and the microbiome	40
Maternal stress, placental 11β-hydroxysteroid dehydrogenase type 2, and infant HPA axis development in humans: Psychosocial and physiological pathways	39
Placental macrophages: Origin, heterogeneity, function and role in pregnancy-associated infections	39
Placental pathology in COVID-19 affected pregnant women: A prospective case-control study	36
First trimester biomarkers for prediction of gestational diabetes mellitus	33
The role of obesity and gestational diabetes on placental size and fetal oxygenation	33
Placental structural abnormalities in gestational diabetes and when they develop: A scoping review	33
Update review on five top clinical applications of human amniotic membrane in regenerative medicine	33
Abnormalities of placental development and function are associated with the different fetal growth patterns of hypoplastic left heart syndrome and transposition of the great arteries	31
A crossroad between placental and tumor biology: What have we learnt?	31
Research on nanoparticles in human perfused placenta: State of the art and perspectives	30
Placental miRNAs in feto-maternal communication mediated by extracellular vesicles	30
PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis	29

Novel approaches to combat preeclampsia: from new drugs to innovative delivery	29
Placental small extracellular vesicles: Current questions and investigative opportunities	29
Maternal interventions to prevent adverse fetal programming outcomes due to maternal malnutrition: Evidence in animal models	29
Decreased maternal serum adiponectin and increased insulin-like growth factor-1 levels along with increased placental glucose transporter-1 expression in gestational diabetes mellitus: Possible role i	28
Potential SARS-CoV-2 interactions with proteins involved in trophoblast functions – An in-silico study	27
Fetal exposure to environmental chemicals; insights from placental perfusion studies	27
Placental mitochondrial function in response to gestational exposures	26
CircSFXN1 regulates the behaviour of trophoblasts and likely mediates preeclampsia	25
Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studies	25
Molecular characteristics of established trophoblast-derived cell lines	25
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network	24
Paradigms for investigating invasive trophoblast cell development and contributions to uterine spiral artery remodeling	24
MiR-124–3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor	24
Placental deficiency during maternal SARS-CoV-2 infection	23
T2* placental MRI in pregnancies complicated with fetal congenital heart disease	23
CircLRRK1 targets miR-223-3p to inhibit the proliferation, migration and invasion of trophoblast cells by regulating the PI3K/AKT signaling pathway	22
Umbilical cord plasma-derived exosomes from preeclamptic women induce vascular dysfunction by targeting HMGCS1 in endothelial cells	22
Investigating the risk of maternal-fetal transmission of SARS-CoV-2 in early pregnancy	21
Derivation of endometrial gland organoids from term placenta	21
Quercetin improved histological structure and upregulated adiponectin and adiponectin receptors in the placenta of rats with gestational diabetes mellitus	21
SIRT1 regulates trophoblast senescence in premature placental aging in preeclampsia	21
PFKFB3 regulates lipopolysaccharide-induced excessive inflammation and cellular dysfunction in HTR-8/Svneo cells: Implications for the role of PFKFB3 in preeclampsia	21
Oxidative stress biomarkers in fetal growth restriction with and without preeclampsia	20
3-Dimensional JEG-3 choriocarcinoma cell organoids as a model for trophoblast expansion and differentiation	20
The role of β-HCG and VEGF-MEK/ERK signaling pathway in villi angiogenesis in patients with missed abortion	20
Placental weight centiles adjusted for age, parity and fetal sex	20
The risk factors associated with placenta previa: An umbrella review	20
Structural changes to the brood pouch of male pregnant seahorses (Hippocampus abdominalis) facilitate exchange between father and embryos	20
Cyclosporin A alleviates trophoblast apoptosis and senescence by promoting autophagy in preeclampsia	20
The placental pathology in Coronavirus disease 2019 infected mothers and its impact on pregnancy outcome	19
miR-15b-5p promotes expression of proinflammatory cytokines in human placenta by inhibiting Apelin signaling pathway	19
ELABELA alleviates syncytiotrophoblast hypoxia/reoxygenation injury and preeclampsia-like symptoms in mice by reducing apoptosis	19
Placental magnetic resonance imaging in chronic hypertension: A case-control study	18
The role of maternal–foetal interface inflammation mediated by NLRP3 inflammasome in the pathogenesis of recurrent spontaneous abortion	18
Syncytiotrophoblast stress in early onset preeclampsia: The issues perpetuating the syndrome	18
Air pollution and pre-eclampsia; associations and potential mechanisms	18
Multiscale three-dimensional imaging of the placenta	18
Maternal altitude and risk of low birthweight: A systematic review and meta-analyses	18
Placenta morphology and biomarkers in pregnancies with congenital heart disease – A systematic review	18
Pandemic stress and SARS-CoV-2 infection are associated with pathological changes at the maternal-fetal interface	18
Differentially expressed circular RNAs and the competing endogenous RNA network associated with preeclampsia	18
Clinical factors associated with a placenta accreta spectrum	17
Placental blood flow sensing and regulation in fetal growth restriction	17
High altitude regulates the expression of AMPK pathways in human placenta	17
Serum miRNA biomarker discovery for placenta accreta spectrum	17
Gestational trophoblastic neoplasia: Novelties and challenges	16
Second trimester uterine arteries pulsatility index is a function of placental pathology and provides insights on stillbirth aetiology: A multicenter matched case-control study	16
Endocytosis in the placenta: An undervalued mediator of placental transfer	16
Hypoxic effects on the mitochondrial content and functions of the placenta in fetal growth restriction	16
Transgenic expression of human C19MC miRNAs impacts placental morphogenesis	16

Transient loss of endothelial cells in human spiral artery remodelling during early pregnancy: Challenging the dogma	16
Isolation and characterization human chorion membrane trophoblast and mesenchymal cells	16
From stem cells to spiral arteries: A journey through early placental development	15
Placental hypoxia: What have we learnt from small animal models?	15
Preeclampsia: inflammatory signature of decidual cells in early manifestation of disease	15
Paternal low protein diet and the supplementation of methyl-donors impact fetal growth and placental development in mice	15
The effects of exercise during pregnancy on placental composition: A systematic review and meta-analysis	15
microRNA-210/ Long non-coding RNA MEG3 axis inhibits trophoblast cell migration and invasion by suppressing EMT process	15
MiR-193b inhibits autophagy and apoptosis by targeting IGFBP5 in high glucose-induced trophoblasts	15
Maternal, fetal and placental regulation of placental iron trafficking	15
Low-level SARS-CoV-2 viremia coincident with COVID placentitis and stillbirth	15
Diminished trophoblast differentiation in early onset preeclampsia	15
Iodothyronine deiodinase 2 (DiO2) regulates trophoblast cell line cycle, invasion and apoptosis; and its downregulation is associated with early recurrent miscarriage	15
Pericytes on placental capillaries in terminal villi preferentially cover endothelial junctions in regions furthest away from the trophoblast	15
Third trimester stillbirth during the first wave of the SARS-CoV-2 pandemic: Similar rates with increase in placental vasculopathic pathology	15
Know the game: Insights to help early career researchers successfully navigate academia	15
Extracellular vesicles and their role in gestational diabetes mellitus	15
Maternal obesity increases the risk of fetal cardiac dysfunction via visceral adipose tissue derived exosomes	14
Understanding the uterine artery Doppler waveform and its relationship to spiral artery remodelling	14
Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition	14
Sulforaphane improves vascular reactivity in mouse and human arteries after “preeclamptic-like” injury	14
Diagnostic capacity of sFlt-1/PlGF ratio in fetal growth restriction: A systematic review and meta-analysis	14
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway	14
Neutrophils in preterm birth: Friend or foe?	14
Maternal, placental, and fetal distribution of titanium after repeated titanium dioxide nanoparticle inhalation through pregnancy	14
The clinical impact of maternal COVID-19 on mothers, their infants, and placentas with an analysis of vertical transfer of maternal SARS-CoV-2-specific IgG antibodies	14
Circ-AK2 is associated with preeclampsia and regulates biological behaviors of trophoblast cells through miR-454–3p/THBS2	14
Lactobacillus crispatus promotes invasion of the HTR-8/SVneo trophoblast cell line	14
Placental apoptotic markers are associated with placental morphometry	14
Identification and validation of DNA methylation changes in pre-eclampsia	14
SIRT3 deficiency affects the migration, invasion, tube formation and necroptosis of trophoblast and is implicated in the pathogenesis of preeclampsia	13
Molar pregnancy in the last 50 years: A bibliometric analysis of global research output	13
Brood pouch evolution in pipefish and seahorse based on histological observation	13
Aberrantly up-regulated miR-142-3p inhibited the proliferation and invasion of trophoblast cells by regulating FOXM1	13
Evaluation of vertical transmission of SARS-CoV-2 in utero: Nine pregnant women and their newborns	13
Platelet alloimmunization is associated with low grade chronic histiocytic intervillositis - A new link to a rare placental lesion?	13
The metabolic landscape of decidua in recurrent pregnancy loss using a global metabolomics approach	13
MRI based morphological examination of the placenta	13
Perfusion fraction derived from IVIM analysis of diffusion-weighted MRI in the assessment of placental vascular malperfusion antenatally	13
O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes	13
Polymorphisms of hypertension susceptibility genes as a risk factors of preeclampsia in the Caucasian population of central Russia	13
Doppler studies of placental function	13
Upregulation of METTL14 contributes to trophoblast dysfunction by elevating FOXO3a expression in an m6A-dependent manner	13
Dysregulated miRNAs contribute to altered placental glucose metabolism in patients with gestational diabetes via targeting GLUT1 and HK2	13
Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth	13
First trimester serum PIGF is associated with placenta accreta	13
Suppression of human trophoblast syncytialization by human cytomegalovirus infection	12
Chronic villitis of unknown etiology: Investigations into viral pathogenesis	12
Current understanding of autophagy in intrahepatic cholestasis of pregnancy	12
Evaluation of oxidative stress markers in subtypes of preeclampsia: A systematic review and meta-analysis	12
The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue	12
Massive perivillous fibrin deposition of the placenta and pregnancy outcome: A retrospective observational study	12
Prediction of hypertension in pregnancy in high risk women using maternal factors and serial placental profile in second and third trimester	12
Maternal platelets at the first trimester maternal-placental interface – Small players with great impact on placenta development	12
miR-486-5p inhibits invasion and migration of HTR8/SVneo trophoblast cells by down-regulating ARHGAP5	12
Magnetic resonance imaging of placentome development in the pregnant Ewe	12
Placental dysfunction: The core mechanism for poor neurodevelopmental outcomes in the offspring of preeclampsia pregnancies	12
The road (not) taken – Placental transfer and interspecies differences	12
Seroprevalence of SARS-CoV-2 immunoglobulins in pregnant women and neonatal cord blood from a highly impacted region	11
Trimethylamine N-Oxide increases soluble fms-like tyrosine Kinase-1 in human placenta via NADPH oxidase dependent ROS accumulation	11
Regulation of trophoblast cell invasion by Pyruvate Kinase isozyme M2 (PKM2)	11
Circ_0015382 is associated with preeclampsia and regulates biological behaviors of trophoblast cells through miR-149-5p/TFPI2 axis	11
Folding of the syncytiotrophoblast basal plasma membrane increases the surface area available for exchange in human placenta	11
Prenatal interventions for fetal growth restriction in animal models: A systematic review	11
Amniotic fluid stem cells as a novel strategy for the treatment of fetal and neonatal neurological diseases	11
Impact of location on placentation in live tubal and cesarean scar ectopic pregnancies	11
First-trimester utero-placental (vascular) development and embryonic and fetal growth: The Rotterdam periconception cohort	11
Comparative study of placental T2* and intravoxel incoherent motion in the prediction of fetal growth restriction	11
Placentation and embryo death in the plains viscacha (Lagostomus maximus)	11
Chronic villitis: Refining the risk ratio of recurrence using a large placental pathology sample	11
The abnormal expression of Tim-3 is involved in the regulation of myeloid-derived suppressor cells and its correlation with preeclampsia	11
FGF15/FGF19 alleviates insulin resistance and upregulates placental IRS1/GLUT expression in pregnant mice fed a high-fat diet	11
Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK/ERK 1/2 pathway	11
Placental MRI: Development of an MRI compatible ex vivo system for whole placenta dual perfusion	11
Extracellular vesicles- crucial players in human pregnancy	11
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia	11
T2* weighted fetal MRI and the correlation with placental dysfunction	11
T2* weighted placental MRI in relation to placental histology and birth weight	11
The m6A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression	10
A simple method to isolate term trophoblasts and maintain them in extended culture	10

Association between maternal hemoglobin concentration and placental weight to birthweight ratio: The Japan Environment and Children's Study (JECS)	10
Influence of culture media on the derivation and phenotype of fetal-derived placental mesenchymal stem/stromal cells across gestation	10
Global DNA methylation in placental tissues from pregnant with preeclampsia: A systematic review and pathway analysis	10
Dynamic contrast enhanced magnetic resonance imaging: A review of its application in the assessment of placental function	10
Increased placental expression of angiotensin-converting enzyme 2, the receptor of SARS-CoV-2, associated with hypoxia in twin anemia-polycythemia sequence (TAPS)	10
Predictors of adverse neonatal outcome in pregnancies complicated by placenta previa	10
Recurrence risk of villitis of unknown etiology: Analysis of a large retrospective cohort study, systematic review and meta-analysis	10
Elevated placental histone H3K4 methylation via upregulated histone methyltransferases SETD1A and SMYD3 in preeclampsia and its possible involvement in hypoxia-induced pathophysiological process	10
Salivary cytokines levels, maternal periodontitis and infants' weight at birth: A cohort study in pregnant women with obesity	10
The association between first trimester placental biomarkers and placental lesions of maternal vascular malperfusion	10
Coronavirus disease 2019 and the placenta: A literature review	10
Krüppel-like factor 6 (KLF6) requires its amino terminal domain to promote villous trophoblast cell fusion	10
Connecting the dots on vertical transmission of SARS-CoV-2 using protein-protein interaction network analysis – Potential roles of placental ACE2 and ENDOU	10
The singular case of multiple chorangioma syndrome in an IVF pregnancy. Analysis of the case and review of literature	10
Isolated fetal neural tube defects associate with increased risk of placental pathology: Evidence from the Collaborative Perinatal Project	10
The association between vein-to-vein anastomoses and birth weight discordance in relation to placental sharing in monochorionic twin placentas	10
Maternal thyroid profile in first and second trimester of pregnancy is correlated with gestational diabetes mellitus through machine learning	10
Integrated analysis of multiple microarray studies to identify novel gene signatures in preeclampsia	10
STAT3 signaling pathway is involved in the pathogenesis of miscarriage	10
The impact of advanced maternal age on pregnancy and offspring health: A mechanistic role for placental angiogenic growth mediators	10
Uterine damage induces placenta accreta and immune imbalance at the maternal-fetal interface in the mouse	10
Associations between AGT, MTHFR, and VEGF gene polymorphisms and preeclampsia in the Chinese population	10
Cannabinoids and the placenta: Receptors, signaling and outcomes	10
Structure of the paraplacenta and the yolk sac placenta of the viviparous Australian sharpnose shark, Rhizoprionodon taylori	9
The effects of COVID-19 on placental morphology	9
Downregulation of miR-33a/b and miR-181a contributes to recurrent pregnancy loss by upregulating S1PR1 and repressing regulatory T cell differentiation	9
Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy	9
Epidemiology of placenta accreta spectrum disorders in Chinese pregnant women: A multicenter hospital-based study	9
Analysis of mitochondrial regulatory transcripts in publicly available datasets with validation in placentae from pre-term, post-term and fetal growth restriction pregnancies	9
Interventions for placental insufficiency and fetal growth restriction	9
The diagnostic value of two-dimensional shear wave elastography in gestational diabetes mellitus	9
Cleavage of the soluble (pro)renin receptor (sATP6AP2) in the placenta	9
Beyond fusion: A novel role for ERVW-1 in trophoblast proliferation and type I interferon receptor expression	9
Cytogenomics of six human trophoblastic cell lines	9
Pulsatility effects of flow on vascular tone in the fetoplacental circulation	9
Diagnostic accuracy of fetal growth charts for placenta-related fetal growth restriction	9
Role of osteopontin (OPN) in uterine spiral artery remodeling	9
A disintegrin and metalloproteinase 12 (ADAM12) is reduced at 36 weeks’ gestation in pregnancies destined to deliver small for gestational age infants	9
The polarized localization of lipoprotein receptors and cholesterol transporters in the syncytiotrophoblast of the placenta is reproducible in a monolayer of primary human trophoblasts	9
Three-dimensional visualisation of the feto-placental vasculature in humans and rodents	9
Fatty acids in the placenta of appropiate- versus small-for-gestational-age infants at term birth	9
Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability	9
Exploring the impact of HIV infection and antiretroviral therapy on placenta morphology	9
The predictive value of pre-delivery laboratory test results for the severity of placental abruption and pregnancy outcome	9
Umbilical cord compromise versus other clinical conditions predisposing to placental fetal vascular malperfusion	9
Gardnerella vaginalis infection in pregnancy: Effects on placental development and neonatal outcomes	9
TAM and TIM receptors mRNA expression in Zika virus infected placentas	9
Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies	9
Retinopathy of prematurity in infants without fetal growth restriction is decreased with the progression of acute histologic chorioamnionitis: New observation as a protective factor against retinopath	9
Relationship between placental elastography, maternal pre-pregnancy body mass index and gestational weight gain	9
CircHIPK3 contributes to human villous trophoblast growth, migration and invasion via modulating the pathway of miR-346/KCMF1	9
AOPPs induce HTR-8/SVneo cell apoptosis by downregulating the Nrf-2/ARE/HO-1 anti-oxidative pathway: Potential implications for preeclampsia	9
Effect of metformin on biomarkers of placental- mediated disease: A systematic review and meta-analysis	9
Use of intravoxel incoherent motion MRI to assess placental perfusion in normal and Fetal Growth Restricted pregnancies on their third trimester	9
Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia	8
Placental pathology in cancer during pregnancy and after cancer treatment exposure	8
miR-2115-3p inhibits ferroptosis by downregulating the expression of glutamic-oxaloacetic transaminase in preeclampsia	8
Severe early-onset PE with or without FGR in Chinese women	8
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling	8
Current knowledge on genetic variants shaping placental transcriptome and their link to gestational and postnatal health	8
Vitamin D alleviates hypoxia/reoxygenation-induced injury of human trophoblast HTR-8 cells by activating autophagy	8
On the use of multicompartment models of diffusion and relaxation for placental imaging	8
Placental chemical elements concentration in small fetuses and its relationship with Doppler markers of placental function	8
SKAP2 is downregulated in the villous tissues of patients with missed abortion and regulates growth and migration in trophoblasts through the WAVE2-ARP2/3 signaling pathway	8
Placental transport of parabens studied using an ex-vivo human perfusion model	8
Analysis of cell-free fetal DNA in 16,843 pregnant women from a single center in China using targeted sequencing approach	8
A re-examination of the origins of placental bed giant cells	8
Addressing microchimerism in pregnancy by ex vivo human placenta perfusion	8
G-CSF: A vehicle for communication between trophoblasts and macrophages which may cause problems in recurrent spontaneous abortion	8
Endothelial nitric oxide deficiency results in abnormal placental metabolism	8
Shared developmental pathways of the placenta and fetal heart	8
Placental pathologic features in thyroid autoimmunity	8
Decreased tight junction protein intensity in the placenta of porcine reproductive and respiratory syndrome virus-2 infected fetuses	8
Identification of placental androgen receptor isoforms in a sheep model of maternal allergic asthma	8
Periconceptional maternal and paternal homocysteine levels and early utero-placental (vascular) growth trajectories: The Rotterdam periconception cohort	8
Dynamic measurement of amnion thickness during loading by speckle pattern interferometry	7
Role of adipose tissue in regulating fetal growth in gestational diabetes mellitus	7
Maternal hemodynamics for the identification of early fetal growth restriction in normotensive pregnancies	7
Placenta pathology in recipient versus donor oocyte derivation for in vitro fertilization in a setting of hypertensive disorders of pregnancy and IUGR	7
Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats	7
Maternal circulating SPINT1 is reduced in small-for-gestational age pregnancies at 26 weeks: Growing up in Singapore towards health outcomes (GUSTO) cohort study	7
Differential expression of serum proteins before 20 weeks gestation in women with hypertensive disorders of pregnancy: A potential role for SH3BGRL3	7
TREM-1 amplifies trophoblastic inflammation via activating NF-κB pathway during preeclampsia	7
Evaluation of placental oxygenation in fetal growth restriction using blood oxygen level-dependent magnetic resonance imaging	7
Exploration of fetal growth restriction induced by vitamin D deficiency in rats via Hippo-YAP signaling pathway	7
CD15 immunostaining improves placental diagnosis of fetal hypoxia	7
Characterization of the temporal, cell-specific and interferon-inducible patterns of indoleamine 2,3 dioxygenase 1 (IDO1) expression in the human placenta across gestation	7
The effects of high-density lipoprotein and oxidized high-density lipoprotein on forskolin-induced syncytialization of BeWo cells	7
Percentiles of intrauterine placental volume and placental volume relative to fetal volume: A prospective magnetic resonance imaging study	7
Placental Changes in the serotonin transporter (Slc6a4) knockout mouse suggest a role for serotonin in controlling nutrient acquisition	7
Changes in placental elastography in the third trimester - Analysis using a linear mixed effect model	7
Lateral placentation and adverse perinatal outcomes	7
Placental pathology in women with HIV	7
Comprehensive analyses of DNA methylation of the TIMP3 promoter in placentas from early-onset and late-onset preeclampsia	7
Multiscale and multimodal imaging of utero-placental anatomy and function in pregnancy	7