Carcinogenesis

Article	Citations
Editor-In-Chief’s Editorial 2023	69
miR-1304 targets KLK11 to regulate gastric cancer cell proliferation through the mTOR signaling pathway	50
LINC02418 upregulates EPHA2 by competitively sponging miR-372-3p to promote 5-Fu/DDP chemoresistance in colorectal cancer	38
Regulatory mechanisms of PFKFB2 in glycolysis and tumor metabolism: implications for cancer therapy	35
Longitudinal single-cell RNA model aids prediction of EGFR-TKI resistance	29
Cancer-testis non-coding RNA LEF1-AS1 regulates the nuclear translocation of PDCD5 and suppresses its interaction with p53 signaling: a novel target for immunotherapy in esophageal squamous cell carci	29
Identification of HCAR1 as a ferroptosis-related biomarker of gastric cancer based on a novel ferroptosis-related prognostic model and in vitro experiments	29
O-GlcNAcylation of RAB10 promotes hepatocellular carcinoma progression	29
Correction to: Triple-negative breast cancer molecular subtypes and potential detection targets for biological therapy indications	26
Redefining pancreatic cancer management with tumor-agnostic precision medicine	26
The environmental carcinogen benzo[a]pyrene regulates epigenetic reprogramming and metabolic rewiring in a two-stage mouse skin carcinogenesis model	25
Expression of Concern: The promoting effects of hsa_circ_0050102 in pancreatic cancer and the molecular mechanism by targeting miR-1182/NPSR1	23
miR-22 promotes immunosuppression via activating JAK/STAT3 signaling in cutaneous squamous cell carcinoma	22
Prognostic value of circulating tumor DNA in different cancer types detected by ultra-low-pass whole-genome sequencing: a systematic review and patient-level survival data meta-analysis	21
Editor-in-Chief’s Note—Thank you to Reviewers	20
miR-3154 promotes hepatocellular carcinoma progression via suppressing HNF4α	19
Intratumoral vitamin D signaling and lethal prostate cancer	19
Association between new plasma inflammatory markers and risk of colorectal neoplasms in individuals over 50 years old	19
Ehm2 transcript variant 1 inhibits breast cancer progression and increases E-cadherin stability	18
LMO3 is a suppressor of the basal-like/squamous subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism	18
Solamargine enhanced gefitinib antitumor effect via regulating MALAT1/miR-141-3p/Sp1/IGFBP1 signaling pathway in non-small cell lung cancer	18
Long non-coding RNA NRAV in the 12q24.31 risk locus drives gastric cancer development through glucose metabolism reprogramming	17
α5-nAChR/STAT3/CD47 axis contributed to nicotine-related lung adenocarcinoma progression and immune escape	17
The tumour microenvironment in paediatric rhabdomyosarcomas: a systematic review	17
SRSF3 knockdown-induced cellular senescence as a possible therapeutic strategy for non-small cell lung cancer	16

Machine learning based on biological context facilitates the identification of microvascular invasion in intrahepatic cholangiocarcinoma	16
Long noncoding RNA XIST: a novel independent prognostic biomarker for patients with ABC-DLBCL receiving R-CHOP treatment	16
Copine 1 predicts poor clinical outcomes by promoting M2 macrophage activation in ovarian cancer	16
SIAH1/CTR9 axis promotes the epithelial–mesenchymal transition of hepatocellular carcinoma	16
DUT enhances drug resistance to proteasome inhibitors via promoting mitochondrial function in multiple myeloma	15
Prognostic value of exosomal noncoding RNA in hepatocellular carcinoma: a meta-analysis	15
Establishing a new-onset diabetes-related metabolism signature for predicting the prognosis and immune landscape in pancreatic cancer	15
ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation	14
Endometrial hyperplasia with loss of APC in a novel population of Lyz2-expressing mouse endometrial epithelial cells	14
Antibody–drug conjugates in breast cancer	14
The impact of reproductive factors on breast tumor and normal-adjacent tissue immune profile from menarche to menopause	14
SLC38A6, regulated by EP300-mediated modifications of H3K27ac, promotes cell proliferation, glutamine metabolism and mitochondrial respiration in hepatocellular carcinoma	14
Immune-related genes for the prediction of response to imatinib therapy in chronic myeloid leukemia	14
MPZL1 upregulation promotes tumor metastasis and correlates with unfavorable prognosis in non-small cell lung cancer	14
PPM1G promotes the progression of lung adenocarcinoma by inhibiting p38 activation via dephosphorylation of MEK6	14
Urinary glyphosate levels and association with mortality in the 2013–16 National Health and Nutrition Examination Survey	14
MALAT1 regulates network of microRNA-15a/16–VEGFA to promote tumorigenesis and angiogenesis in multiple myeloma	13
BRAF V600E-induced distinct DNA damage response defines the therapeutic potential of p53 activation for TP53 wild-type colorectal cancer	13
Outcome of clinical experience of introducing a patient with secondary systemic AL-amyloidosis associated with multiple myeloma	13
CYR61 confers chemoresistance by upregulating survivin expression in triple-negative breast cancer	13
Genetic variants in glycosylation pathways are associated with colorectal cancer risk	13
Genomic and transcriptomic characterization of gamma ray- and heavy-ion-induced precursor B-cell lymphomas in B6C3F1 mice: radiation-type-dependent interstitial chromosomal deletions at tumor-suppress	13
Germline alteration analysis reveals EPHB4R91H mutation as a key player in multiple primary lung tumors	13
AKT/GSK-3beta/VEGF signaling is involved in P2RY2 activation-induced the proliferation and metastasis of gastric cancer	12
Actinomycin D synergizes with Doxorubicin in triple-negative breast cancer by inducing P53-dependent cell apoptosis	12
LncRNA-encoded peptide LRRC75A-AS1-ORF3 suppresses anti-tumor immunity in colorectal cancer through mitophagy-mediated attenuation of cGAS-STING signaling	12
SMARCA4/BRG1 deficiency induces a targetable dependence on oxidative phosphorylation in clear cell renal cell carcinoma	12
SSH1 promotes progression of intrahepatic cholangiocarcinoma via p38 MAPK-CXCL8 axis	12
Sevoflurane inhibits lung cancer development by promoting FUS1 transcription via downregulating IRF6	12
From precursor to cancer: decoding the intrinsic and extrinsic pathways of pancreatic intraepithelial neoplasia progression	12
LncRNA CCAT1 participates in pancreatic ductal adenocarcinoma progression by forming a positive feedback loop with c-Myc	11
Elevated expression of the membrane-anchored serine protease TMPRSS11E in NSCLC progression	11
E3 ubiquitin ligase RNF148 functions as an oncogene in colorectal cancer by ubiquitination-mediated degradation of CHAC2	11
Somatic p53 mutations that are markedly overrepresented in lung cancer confer resistance to reactive oxygen species-induced cell death	11
CacyBP promotes the development of lung adenocarcinoma by regulating OTUD5	11
Tumor-associated astrocytes inhibit tumor cell apoptosis through TNF-α–TNF receptor 2–NF-κB pathway in lung cancer brain metastasis	11
Correction to: p62/SQSTM1 interacts with vimentin to enhance breast cancer metastasis	11
MAPK3 modulates enhancer–promoter interactions of SKAP2 in acute myeloid leukemia	11
Comparison of radiation-related cancer risks from the atomic bomb survivors with studies of pediatric medical radiation exposure	11
A polymorphic variant in telomere maintenance is associated with worrisome features and high-risk stigmata development in IPMNs	11
ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment	10
Pan-cancer analysis of G6PD carcinogenesis in human tumors	10
m6A-modified circASXL1 promotes proliferation and migration of ovarian cancer through the miR-320d/RACGAP1 axis	10
Dietary phytoestrogen intake and ovarian cancer risk: a prospective study in the prostate, lung, colorectal and ovarian (PLCO) cohort	10
Cancer-associated fibroblasts promote cancer stemness by inducing expression of the chromatin-modifying protein CBX4 in squamous cell carcinoma	10
NamiRNA-enhancer network of miR-492 activates the NR2C1-TGF-β/Smad3 pathway to promote epithelial-mesenchymal transition of pancreatic cancer	9
LncRNAs act as modulators of macrophages within the tumor microenvironment	9
Stem cells, Notch-1 signaling, and oxidative stress: a hellish trio in cancer development and progression within the airways. Is there a role for natural compounds?	9
Copper in colorectal cancer patients: a systematic review and meta-analysis	9
Olfactomedin 4 promotes gastric cancer cell G2/M progression and serves as a therapeutic target in gastric adenocarcinoma	9

Macrophage migration inhibitory factor as a prognostic biomarker in multiple myeloma: clinical significance and in vitro effects	9
Expression profile of Claudins 3, 4, and 7 in breast tumors and its correlation with clinicopathological features	9
Associations of prediagnostic serum liver enzyme levels with lung cancer risk in predominantly low-income African and European Americans	8
Adverse events and recent advances in CAR-T-cell therapy	8
CRL4DCAF4 E3 ligase-mediated degradation of MEN1 transcriptionally reactivates hTERT to sustain immortalization in colorectal cancer cells	8
Integrative analysis of enrichment and prognostic value of ferroptosis-related genes and pathways in multiple myeloma	8
Bipolar high-frequency electric welding in radical resection of frontal sinus tumors	8
Targeted sequencing and functional interrogation identified novel variant at 12q14.2 associated with risk of ovarian cancer in Han Chinese women	8
Triple-negative breast cancer molecular subtypes and potential detection targets for biological therapy indications	8
Symposium report—ethical and social considerations regarding return of secondary findings in atomic bomb survivors	8
Role of P450 enzymes of the Cyp2abfgs gene subfamilies in tobacco smoke-induced lung tumorigenesis in mice	8
BRINP3 promotes lung adenocarcinoma by enhancing CLOCK-mediated transcriptional regulation of CRYZL1 and activating the AKT pathway	8
Overview and future studies of potential hereditary effects of parental exposure to atomic bomb radiation on their offspring	8
CCL18 promotes migration and invasion of multiple myeloma cells and is associated with poor prognosis	8
Thymoquinone inhibits lung cancer stem cell properties via triggering YAP degradation	8
LncRNA UCA1 promotes vasculogenic mimicry by targeting miR-1-3p in gastric cancer	7
TMEM16A inhibits autophagy and promotes the invasion of hypopharyngeal squamous cell carcinoma through mTOR pathway	7
CDK12 is a promising therapeutic target for the transcription cycle and DNA damage response in metastatic osteosarcoma	7
Call for Applications	7
The influence of homologous recombination repair on temozolomide chemosensitivity in gliomas	7
Dual activation of autophagy and mTOR by TFE3 fusions promotes tumorigenesis in rearranged renal cell carcinoma	7
Mechanisms of tumor-associated macrophages promoting tumor immune escape	7
HOXA10 promote pancreatic cancer progression via directly activating canonical NF-κB signaling pathway	7
Efficacy of depatuxizumab mafodotin (ABT-414) in preclinical models of head and neck cancer	7
HS-10296 (almonertinib) enhances radiosensitivity in EGFR-mutant nonsmall cell lung cancer (including T790M) through inhibition of EGFR downstream signaling and DNA damage repair	7
Plasma thioredoxin reductase: a potential diagnostic biomarker for gastric cancer	7
Morphology dynamics in intestinal crypt during postnatal development affect age-dependent susceptibility to radiation-induced intestinal tumorigenesis in Apc Min/+ mice	7
miR-21-5p/Tiam1-mediated glycolysis reprogramming drives breast cancer progression via enhancing PFKL stabilization	7
SNCA inhibits epithelial–mesenchymal transition and correlates to favorable prognosis of breast cancer	7
Asbestos burden in lungs of mesothelioma patients with pleural plaques, lung fibrosis and/or ferruginous bodies at histology: a postmortem SEM-EDS study	6
Retraction of: Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion	6
Recent evolution of risk analyses in atomic bomb survivor studies: new methods and applications	6
Utilizing the Life Span Study data in NASA astronaut cancer risk assessment	6
Identification and prioritization of tumour-associated antigens for immunotherapeutic and diagnostic capacity in epithelial ovarian cancer: a systematic literature review	6
Targeting cyclin-dependent kinase 7—association between CDK7 and pMED1 expression in prostate cancer tissue	6
The ubiquitin E3 ligase MDM2 induces chemoresistance in colorectal cancer by degradation of ING3	6
A watercress drink increases detoxification of common environmental carcinogens such as acrolein and benzene: results of a randomized clinical trial	6
miR-424-3p promotes metastasis of hepatocellular carcinoma via targeting the SRF-STAT1/2 axis	6
Integrative functional screen of genomic loci uncovers CCND2 and its genetic regulatory mechanism in colorectal cancer development	6
The anaphase-promoting complex/cyclosome co-activator, Cdh1, is a novel target of human papillomavirus 16 E7 oncoprotein in cervical oncogenesis	6
Prognostic microRNA signature for estimating survival in patients with hepatocellular carcinoma	6
Emerging evidence on the role of breast microbiota on the development of breast cancer in high-risk patients	6
Smoking, alcohol, and colon cancer survival are modified by immune biomarkers: a population-representative study	6
Genome-wide identification of aberrant alternative splicing and RNA-binding protein regulators in acute myeloid leukaemia which may contribute to immune microenvironment remodelling	6
Long non-coding RNA KB-1460A1.5 promotes ferroptosis by inhibiting mTOR/SREBP-1/SCD1-mediated polyunsaturated fatty acid desaturation in glioma	6
Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring	6
Construction and testing of a risk prediction classifier for cardia carcinoma	6
CircCDK17 promotes the proliferation and metastasis of ovarian cancer cells by sponging miR-22-3p to regulate CD147 expression	5
Genomic and transcriptomic significance of multiple primary lung cancers detected by next-generation sequencing in clinical settings	5
Retraction and replacement of: microRNA involvement in human cancer	5
The HPV16 E6, E7/miR-23b-3p/ICAT signaling axis promotes proliferation, migration, invasion and EMT of cervical cancer cells	5
ETS1 deficiency in macrophages suppresses colorectal cancer progression by reducing the F4/80+TIM4+ macrophage population	5
Reactions of [13C]-labelled tobacco smoke with DNA to generate selected adducts formed without metabolic activation	5
Human papillomavirus (HPV) DNA methylation changes in HPV-associated head and neck cancer	5
Aqueous extracts of Ocimum gratissimum mitigate colitis and protect against AOM/DSS-induced colorectal cancer in mice	5
The evolving role for surgery in pancreatic cancer	5
Inhibition of phospholipase D1 reduces pancreatic carcinogenesis in mice partly through a FAK-dependent mechanism	5
GPS2 confers l-asparaginase resistance in acute lymphoblastic leukemia cells through ATF4/ASNS axis	5
Cancer-associated fibroblasts-derived exosome-mediated transfer of miR-345-5p promotes the progression of colorectal cancer by targeting CDKN1A	5
Role of colorectal cancer-derived exosomes in modulating macrophage phenotype during tumor development	5
Colorectal cancer cells with high metastatic potential drive metastasis by transmitting exosomal miR-20a-3p through modulating NF1/MAPK pathway	5
MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK–ERK and AP-1 pathways	5
Plasma proteomic profiling identified prognostic indicators with therapeutic potential for colorectal cancer	5
An update on the formation in tobacco, toxicity and carcinogenicity of Nʹ-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone	5
Transposable elements alter gene expression and may impact response to cisplatin therapy in ovarian cancer	5
Mutational signatures and increased retrotransposon insertions in xeroderma pigmentosum variant skin tumors	5
Intratumoral microbiota: new frontiers in tumor immunity	5
LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome-dependent degradation	5
Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer patients	5
miR-4461 inhibits liver cancer stem cells expansion and chemoresistance via regulating SIRT1	5
FZD6 promotes 5-fluorouracil resistance through inhibiting pyroptosis in colorectal cancer	4
Retraction of: Pro-angiogenesis action of arsenic and its reversal by selenium-derived compounds	4
Transgelin: a tumor suppressor candidate in neuroblastoma	4
CD133-containing microvesicles promote cancer progression by inducing M2-like tumor-associated macrophage polarization in the tumor microenvironment of colorectal cancer	4
Editor-in-Chief’s Note—Thank you to Reviewers	4
Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression	4
Inhibition of lysosomal acid β-glucosidase induces cell apoptosis via impairing mitochondrial clearance in pancreatic cancer	4
ACSL4: a double-edged sword target in multiple myeloma, promotes cell proliferation and sensitizes cell to ferroptosis	4
Ginseng mediates its anticancer activity by inhibiting the expression of DNMTs and reactivating methylation-silenced genes in colorectal cancer	4
Understanding the role of dopamine in cancer: past, present and future	4

Editor-in-Chief’s Note—Thank you to Reviewers	4
Pathological point of view on the atomic bomb-related solid cancers	4
Retraction of: Genetic and clinical characteristics of BRCA-associated hereditary breast cancer in the West region of Kazakhstan	4
A dual approach to glioblastoma treatment with epigenetic reprogramming and neurogenetic modulation	4
Advanced glycation end products promote the progression of endometrial cancer via activating the RAGE/CHKA/PI3K/AKT signaling pathway	4
The role of interleukin 17 in cancer: a systematic review	4
Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels	4
tRF-29-79 regulates lung adenocarcinoma progression through mediating glutamine transporter SLC1A5	3
Dehydroabietylamine exerts antitumor effects by affecting nucleotide metabolism in gastric cancer	3
Sitravatinib combined with PD-1 blockade enhances cytotoxic T-cell infiltration by M2 to M1 tumor macrophage repolarization in esophageal adenocarcinoma	3
Polo-like kinase 4 (PLK4) as a therapeutic target in breast cancer	3
Correction to: Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer	3
The BET inhibitor GNE-987 effectively induces anti-cancer effects in T-cell acute lymphoblastic leukemia by targeting enhancer regulated genes	3
TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway	3
Splicing transcriptome-wide association study to identify splicing events for pancreatic cancer risk	3
ARID1Amutations in cancer development: mechanism and therapy	3
Detection of DNA adducts derived from the tobacco carcinogens, benzo[a]pyrene and dibenzo[def,p]chrysene in human oral buccal cells	3
Risk of clonal hematopoiesis in families exposed to radiation following the Chornobyl accident	3
Amlodipine, an L-type Ca2+ channel inhibitor, regulates release of extracellular vesicles from tumor cells	3
Enhancing carboplatin sensitivity in ovarian cancer cells by blocking the mercapturic acid pathway transporter	3
Constitutive epidermal expression of osteopontin in osteopontin-null mice restores ultraviolet B-induced cutaneous squamous cell carcinomas to wild-type levels	3
Correction to: Epigenetic silencing of O6 -methylguanine DNA methyltransferase gene in NiS-transformed cells	3
TERT and BRAF V600E mutations in thyroid cancer of World Trade Center Responders	3
Andrew Zloza, MD, PhD (1978–2024)	3
LncRNA CARD8-AS1 suppresses lung adenocarcinoma progression by enhancing TRIM25-mediated ubiquitination of TXNRD1	3
Age-related macrophage alterations are associated with carcinogenesis of colorectal cancer	3
The ubiquitin ligase STUB1 suppresses tumorigenesis of renal cell carcinomas through regulating YTHDF1 stability	3
Triterpenoid ursolic acid regulates the environmental carcinogen benzo[a]pyrene-driven epigenetic and metabolic alterations in SKH-1 hairless mice for skin cancer interception	3
Co-targeting KRASG12D and the HER family is efficacious in colorectal cancer	3
Effect of vitamin E δ-tocotrienol and aspirin on Wnt signaling in human colon cancer stem cells and in adenoma development in APCmin/+ mice	3
LncRNA MEG3 suppresses prostate cancer progression by mediating macrophage polarization via the miR-148a-3p/ARRDC3 signaling axis	3
Retraction of: selective killing of human breast cancer cells by the styryl lactone (R)-goniothalamin is mediated by glutathione conjugation, induction of oxidative stress and marked reactivation of t	3
Eighty years of cancer research after the atomic bombings of Hiroshima and Nagasaki	3