International Endodontic Journal

Article	Citations
The global prevalence of apical periodontitis: a systematic review and meta‐analysis	236
PRILE 2021 guidelines for reporting laboratory studies in Endodontology: A consensus‐based development	192
Present status and future directions: Microbiology of endodontic infections	141
Present status and future directions – irrigants and irrigation methods	109
Efficacy of direct pulp capping for management of cariously exposed pulps in permanent teeth: a systematic review and meta‐analysis	106
Present status and future directions—Vital pulp treatment and pulp preservation strategies	99
PRIASE 2021 guidelines for reporting animal studies in Endodontology: a consensus‐based development	66
PRILE 2021 guidelines for reporting laboratory studies in Endodontology: explanation and elaboration	60
Present status and future directions: Hydraulic materials for endodontic use	58
Factors that affect the outcomes of root canal treatment and retreatment—A reframing of the principles	57
The restoration of root filled teeth: a review of the clinical literature	56
Endodontic management of traumatized permanent teeth: a comprehensive review	54
Clinical cell‐based versus cell‐free regenerative endodontics: clarification of concept and term	52
Outcomes of primary root canal therapy: An updated systematic review of longitudinal clinical studies published between 2003 and 2020	50
Present status and future directions: vertical root fractures in root filled teeth	48
A prospective clinical study investigating the effectiveness of partial pulpotomy after relating preoperative symptoms to a new and established classification of pulpitis	48
Present status and future directions: Surgical endodontics	48
Treatment of pulpal and apical disease: The European Society of Endodontology (ESE) S3‐level clinical practice guideline	45
Present status and future directions: Root resorption	42
Design, metallurgical features, mechanical performance and canal preparation of six reciprocating instruments	42
Present status and future directions – Guided endodontics	42
A macroscopic and histological analysis of radiographically well‐defined deep and extremely deep carious lesions: carious lesion characteristics as indicators of the level of bacterial penetration and	42
Present status and future directions: Canal shaping	41
Biological interactions between calcium silicate‐based endodontic biomaterials and periodontal ligament stem cells: A systematic review of in vitro studies	40
Present status and future directions – Minimal endodontic access cavities	39

Outcome of full pulpotomy in mature permanent molars using 3 calcium silicate‐based materials: A parallel, double blind, randomized controlled trial	39
Publication trends in micro‐CT endodontic research: a bibliometric analysis over a 25‐year period	38
Accuracy and efficiency of guided root‐end resection using a dynamic navigation system: a human cadaver study	38
Heating stability, physical and chemical analysis of calcium silicate‐based endodontic sealers	38
Review of guidance for the selection of regenerative endodontics, apexogenesis, apexification, pulpotomy, and other endodontic treatments for immature permanent teeth	36
Prevalence of root canal treatment worldwide: A systematic review and meta‐analysis	36
European Society of Endodontology position statement: The restoration of root filled teeth	36
Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology (ESE) S3 level clinical pract	36
Application of a new system for classifying root and canal anatomy in studies involving micro‐computed tomography and cone beam computed tomography: Explanation and elaboration	35
A critical analysis of research methods and experimental models to study irrigants and irrigation systems	35
Present status and future directions of intracanal medicaments	33
Factors that influence the outcome of pulpotomy in permanent teeth	32
European Society of Endodontology position statement: Surgical extrusion, intentional replantation and tooth autotransplantation	32
Chemical and mechanical influence of root canal irrigation on biofilm removal from lateral morphological features of simulated root canals, dentine discs and dentinal tubules	31
Present status and future directions: The restoration of root filled teeth	31
Cytocompatibility and bioactive potential of AH Plus Bioceramic Sealer: An in vitro study	31
Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology S3‐level clinical practice gu	31
A critical analysis of research methods and experimental models to study the root canal microbiome	31
Dynamic navigation: a laboratory study on the accuracy and potential use of guided root canal treatment	31
A critical analysis of research methods and experimental models to study pulpitis	29
Present status and future directions: Surgical extrusion, intentional replantation and tooth autotransplantation	29
Effects of concentration of sodium hypochlorite as an endodontic irrigant on the mechanical and structural properties of root dentine: A laboratory study	29
A critical analysis of laboratory and clinical research methods to study root and canal anatomy	28
European Society of Endodontology position statement: endodontic management of traumatized permanent teeth	28
Comparative evaluation of complete and partial pulpotomy in mature permanent teeth with symptomatic irreversible pulpitis: A randomized clinical trial	27
Association between concentration of active MMP‐9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis – a preliminary study	27
Impact of systemic health on treatment outcomes in endodontics	27
Antibacterial activity, cytocompatibility and effect of Bio‐C Temp bioceramic intracanal medicament on osteoblast biology	26
Eggshell derived nano‐hydroxyapatite incorporated carboxymethyl chitosan scaffold for dentine regeneration: A laboratory investigation	26
Effectiveness of root canal filling materials and techniques for treatment of apical periodontitis: A systematic review	26
Identification and validation of novel biomarkers and therapeutics for pulpitis using connectivity mapping	26
The association between apical periodontitis and adverse pregnancy outcomes: a systematic review	26
Present status and future directions: Removal of fractured instruments	25
Outcome of partial and full pulpotomy in cariously exposed mature molars with symptoms indicative of irreversible pulpitis: A randomized controlled trial	25
A critical analysis of research methods and experimental models to study dentinal microcracks	25
Calcium hydroxide‐loaded PLGA biodegradable nanoparticles as an intracanal medicament	24
Five decades of the International Endodontic Journal: Bibliometric overview 1967–2020	24
A critical appraisal of research methods and experimental models for studies on root canal preparation	24
A clinical approach strategy for the diagnosis, treatment and evaluation of external cervical resorption	24
Endodontic pulp revitalization in traumatized necrotic immature permanent incisors: Early failures and long‐term outcomes—A longitudinal cohort study	24
Influence of ultraconservative access cavities on instrumentation efficacy with XP‐endo Shaper and Reciproc, filling ability and load capacity of mandibular molars subjected to thermomechanical cyclin	23
A critical analysis of research methods and experimental models to study biocompatibility of endodontic materials	23
A critical analysis of research methods and experimental models to study root canal fillings	23
Biofilm removal from a simulated isthmus and lateral canal during syringe irrigation at various flow rates: a combined experimental and Computational Fluid Dynamics approach	23
Potential application of immunotherapy for modulation of pulp inflammation: opportunities for vital pulp treatment	22
Evaluation of undergraduate Endodontic teaching in dental schools within Spain	21
Investigating the vascularization capacity of a decellularized dental pulp matrix seeded with human dental pulp stem cells: in vitro and preliminary in vivo evaluations	21
PROBE 2023 guidelines for reporting observational studies in Endodontics: A consensus‐based development study	21
Present status and future directions: Imaging techniques for the detection of periapical lesions	21
The Endodontic Complexity Assessment Tool (E‐CAT): A digital form for assessing root canal treatment case difficulty	21

Do orthodontic tooth movements induce pulp necrosis? A systematic review	21
The impact of apical periodontitis, non‐surgical root canal retreatment and periapical surgery on serum inflammatory biomarkers	21
A laboratory study to test the responses of human dental pulp stem cells to extracts from three dental pulp capping biomaterials	20
Postoperative pain after ultrasonically and laser‐activated irrigation during root canal treatment: a randomized clinical trial	20
The effect of different irrigation solutions and activation techniques on the expression of growth factors from dentine of extracted premolar teeth	19
Present status and future directions: Management of curved and calcified root canals	19
Effectiveness of pulpotomy compared with root canal treatment in managing non‐traumatic pulpitis associated with spontaneous pain: A systematic review and meta‐analysis	19
Present status and future directions – Managing discoloured teeth	19
The management of deep caries in UK primary care: A nationwide questionnaire‐based study	19
A critical analysis of research methods and experimental models to study the physical properties of NiTi instruments and their fracture characteristics	19
An investigation into security, self‐confidence and gender differences related to undergraduate education in Endodontics	19
PRIASE 2021 guidelines for reporting animal studies in Endodontology: explanation and elaboration	18
Effectiveness of revitalization in treating apical periodontitis: A systematic review and meta‐analysis	18
Comparison of design, metallurgy, mechanical performance and shaping ability of replica‐like and counterfeit instruments of the ProTaper Next system	18
Influence of variations in the environmental pH on the solubility and water sorption of a calcium silicate‐based root canal sealer	18
Diverse bacterial profile in extraradicular biofilms and periradicular lesions associated with persistent apical periodontitis	18
Endodontic inflammatory disease: A risk indicator for a first myocardial infarction	18
Comparative analysis of the accuracy of periapical radiography and cone‐beam computed tomography for diagnosing complex endodontic pathoses using a gold standard reference – A prospective clinical stu	18
Tooth survival after endodontic treatment	18
Regenerative endodontic procedures for the treatment of necrotic mature teeth: A preliminary randomized clinical trial	18
Impact of different regenerative techniques and materials on the healing outcome of endodontic surgery: a systematic review and meta‐analysis	18
Model system parameters influence the sodium hypochlorite susceptibility of endodontic biofilms	17
Human amniotic membrane extracellular matrix scaffold for dental pulp regeneration in vitro and in vivo	17
How is carious pulp exposure and symptomatic irreversible pulpitis managed in UK primary dental care?	17
The development of European Society of Endodontology S3‐level guidelines for the treatment of pulpal and apical disease	17
Potential relationship between clinical symptoms and the root canal microbiomes of root filled teeth based on the next‐generation sequencing	17
Doxycycline‐functionalized polymeric nanoparticles inhibit Enterococcus faecalis biofilm formation on dentine	17
Effects of melatonin on insulin signaling and inflammatory pathways of rats with apical periodontitis	16
Unveiling the ChatGPT phenomenon: Evaluating the consistency and accuracy of endodontic question answers	16
Biological parameters, discolouration and radiopacity of calcium silicate‐based materials in a simulated model of partial pulpotomy	16
Influence of ethylenediaminetetraacetic acid on regenerative endodontics: A systematic review	16
Association between dental factors and mortality	16
A critical review ofin vitroresearch methodologies used to study mineralization in human dental pulp cell cultures	16
Effectiveness of diagnosing pulpitis: A systematic review	16
Impact of root canal treatment on high‐sensitivity C‐reactive protein levels in systemically healthy adults with apical periodontitis – a preliminary prospective, longitudinal interventional study	16
Bacteria and virulence factors in periapical lesions associated with teeth following primary and secondary root canal treatment	16
Human three‐dimensional dental pulp organoid model for toxicity screening of dental materials on dental pulp cells and tissue	16
Outcomes reporting in systematic reviews on vital pulp treatment: A scoping review for the development of a core outcome set	16
Influence of metal artefact reduction tool on the detection of vertical root fractures involving teeth with intracanal materials in cone beam computed tomography images: A systematic review and meta‐a	16
Influence of occlusal and proximal caries on the outcome of full pulpotomy in permanent mandibular molar teeth with partial irreversible pulpitis: A prospective study	16
The presence of smear layer affects the antimicrobial action of root canal sealers	15
Impact of several NiTi‐thermally treated instrumentation systems on biomechanical preparation of curved root canals in extracted mandibular molars	15
Research that matters: debunking the myth of the “fracture resistance” of root filled teeth	15
A critical analysis of research methods and experimental models to study apical extrusion of debris and irrigants	15
Present status and future directions: Minimally invasive root canal preparation and periradicular surgery	15
Vital pulp treatment for traumatized permanent teeth: A systematic review	15
A bibliometric analysis of the top 100 most‐cited case reports and case series in Endodontic journals	15
Pulpotomy for treatment of complicated crown fractures in permanent teeth: A systematic review	15
ESE position statement on root resorption	15
A critical analysis of research methods and experimental models to study the load capacity and clinical behaviour of the root filled teeth	15
Effectiveness of adjunct therapy for the treatment of apical periodontitis: A systematic review and meta‐analysis	14
Effect of photobiomodulation on post‐operative symptoms in teeth with asymptomatic apical periodontitis treated with foraminal enlargement: A randomized clinical trial	14
NLRP6‐caspase 4 inflammasome activation in response to cariogenic bacterial lipoteichoic acid in human dental pulp inflammation	14
Excessive caffeine intake increases bone resorption associated with periapical periodontitis in rats	14
Influence of rotational speed on torque/force generation and shaping ability during root canal instrumentation of extracted teeth with continuous rotation and optimum torque reverse motion	14
External cervical resorption – Treatment outcomes and determinants: A retrospective cohort study with up to 10 years of follow‐up	14
Inflammatory profile of apical periodontitis associated with liver fibrosis in rats: histological and immunohistochemical analysis	13
Patient satisfaction with root canal treatment and outcomes in the Swedish public dental health service: A prospective cohort study	13
Effectiveness of endodontic tissue engineering in treatment of apical periodontitis: A systematic review	13
Histological evaluation of a novel phosphorylated pullulan‐based pulp capping material: An in vivo study on rat molars	13
A critical analysis of research methods to study clinical molecular biomarkers in Endodontic research	13
Critical analysis of the reporting quality of randomized trials within Endodontics using the Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE) 2020 quality standard checklist	13
Outcome of single‐ versus two‐visit root canal retreatment in teeth with periapical lesions: A randomized clinical trial	13
Comparison of Bio‐C Pulpo and MTA Repair HP with White MTA: effect on liver parameters and evaluation of biocompatibility and bioactivity in rats	13
A prospective cohort study evaluating the outcome of root canal retreatment in symptomatic mandibular first molars with periapical lesions	13
Effect of low‐level laser therapy on postoperative pain after single‐visit root canal retreatment of mandibular molars: A randomized controlled clinical trial	13
Lipoteichoic acid stimulates the proliferation, migration and cytokine production of adult dental pulp stem cells without affecting osteogenic differentiation	13
Effectiveness of root canal irrigation and dressing for the treatment of apical periodontitis: A systematic review and meta‐analysis of clinical trials	13
Survival and prognostic factors of managing cracked teeth with reversible pulpitis: A 1‐ to 4‐year prospective cohort study	13
Factors that influence the outcomes of surgical endodontic treatment	13
Effectiveness of root canal treatment for vital pulps compared with necrotic pulps in the presence or absence of signs of periradicular pathosis: A systematic review and meta‐analysis	13
A critical analysis of research methods and biological experimental models to study pulp regeneration	13
Preserving dentine in minimally invasive access cavities does not strengthen the fracture resistance of restored mandibular molars	12
Apical pressures generated by several canal irrigation methods: A laboratory study in a maxillary central incisor with an open apex	12
Characterization of nano‐hydroxyapatite incorporated carboxymethyl chitosan composite on human dental pulp stem cells	12
Irisin promotes odontogenic differentiation and angiogenic potential in human dental pulp cells	12
Exosomes derived from stem cells from the apical papilla alleviate inflammation in rat pulpitis by upregulating regulatory T cells	12
In vitro efficacy of a non‐instrumentation technique to remove intracanal multispecies biofilm	12
Effect of preoperative oral administration of steroids in comparison to an anti‐inflammatory drug on postoperative pain following single‐visit root canal treatment – a double‐blind, randomized clinica	12
A laboratory study of the accuracy of three electronic apex locators: influence of embedding media and radiographic assessment of the electronic apical limit	12

Effect of XP‐endo Shaper versus conventional rotary files on postoperative pain and bacterial reduction in oval canals with necrotic pulps: a randomized clinical study	12
Celecoxib treatment dampens LPS‐induced periapical bone resorption in a mouse model	12
Present status and future directions: Managing endodontic emergencies	12
Patient‐related outcomes and Oral Health‐Related Quality of Life in endodontics	12
Chronic apical periodontitis exacerbates atherosclerosis in apolipoprotein E‐deficient mice and leads to changes in the diversity of gut microbiota	11
Cemental tear: Literature review, proposed classification and recommendations for treatment	11
Minimally invasive access cavities: does size really matter?	11
Experimental validation of a computational fluid dynamics model using micro‐particle image velocimetry of the irrigation flow in confluent canals	11
Success rate of permanent teeth pulpotomy using bioactive materials: A systematic review and meta‐analysis of randomized clinical trials	11
Effectiveness of D,L‐2‐hydroxyisocaproic acid (HICA) and alpha‐mangostin against endodontopathogenic microorganisms in a multispecies bacterial–fungal biofilm in anex vivotooth model	11
Multimethod analysis of three rotary instruments produced by electric discharge machining technology	11
Enterococcus faecalis sustained infection induces macrophage pro‐resolution polarization	11
Microbiome in paired root apices and periapical lesions and its association with clinical signs in persistent apical periodontitis using next‐generation sequencing	11
The impact of an enhanced infection control protocol on molar root canal treatment outcome – a randomized clinical trial	11
Present status and future directions—Mechanisms and management of local anaesthetic failures	11
Histology‐based profile of inflammatory mediators in experimentally induced pulpitis in a rat model: screening for possible biomarkers	11
Wnt3a promotes odonto/osteogenic differentiation in vitro and tertiary dentin formation in a rat model	10
Multispecies biofilm removal by a multisonic irrigation system in mandibular molars	10
In vitro physicochemical characterization of five root canal sealers and their influence on an ex vivo oral multi‐species biofilm community	10
Micro‐CT assessment of gap‐containing areas along the gutta‐percha‐sealer interface in oval‐shaped canals	10
Trends of endodontic and periapical status in adult Danish populations from 1997 to 2009: A repeated cross‐sectional study	10
Single nucleotide polymorphisms as a predisposing factor for the development of apical periodontitis—An umbrella review	10
Comparing the anaesthetic efficacy of 1.8 mL and 3.6 mL of anaesthetic solution for inferior alveolar nerve blocks for teeth with irreversible pulpitis: a systematic review and meta‐analysis with tria	10
Does MTA provide a more favourable histological response than other materials in the repair of furcal perforations? A systematic review	10
Assessment of the cytotoxic effects and chemical composition of the insoluble precipitate formed from sodium hypochlorite and chlorhexidine gluconate	10
Outcomes reporting in systematic reviews on surgical endodontics: A scoping review for the development of a core outcome set	10
What ultimately matters in root canal treatment success and tooth preservation: A 25‐year cohort study	10
Quantitative assessment of contrast‐enhancement patterns of the healthy dental pulp by magnetic resonance imaging: A prospective in vivo study	10
The influence of apical periodontitis on circulatory inflammatory mediators in peripheral blood: A prospective case–control study	10
Outcomes reporting in systematic reviews on non‐surgical root canal treatment: A scoping review for the development of a core outcome set	10
Preclinical 3D‐printed laboratory simulation of deep caries and the exposed pulp reduced student anxiety and stress, while increasing confidence and knowledge in vital pulp treatment	10
Hsa‐miRNA‐143‐3p regulates the odontogenic differentiation of human stem cells from the apical papilla by targeting NFIC	10
Isthmus morphology influences debridement efficacy of activated irrigation: A laboratory study involving biofilm mimicking hydrogel removal and high‐speed imaging	10
Ultrasound imaging for the differential diagnosis of periapical lesions of endodontic origin in comparison with histopathology – a systematic review and meta‐analysis	10
Inhibition of receptor‐interacting protein kinase‐3 in the necroptosis pathway attenuates inflammatory bone loss in experimental apical periodontitis in Balb/c mice	10
Instrumentation kinematics does not affect bacterial reduction, post‐operative pain, and flare‐ups: A randomized clinical trial	10
Outcome and associated predictors for nonsurgical management of large cyst‐like periapical lesions: A CBCT‐based prospective cohort study	10
A multicentric survey to evaluate preclinical education in Endodontology in German‐speaking countries	10
Validity and reliability of artificial intelligence chatbots as public sources of information on endodontics	10
Effect of red wine or its polyphenols on induced apical periodontitis in rats	10
Effects of heat in the properties of NaOCl alone and mixed with etidronate and alkaline tetrasodium EDTA	10
Reduction of dual‐species biofilm after sonic‐ or ultrasonic‐activated irrigation protocols: A laboratory study	10