Biomaterials

Article	Citations
Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy	525
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds	475
Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment	281
Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization	279
Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties	249
A physicochemical double cross-linked multifunctional hydrogel for dynamic burn wound healing: shape adaptability, injectable self-healing property and enhanced adhesion	240
M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages	230
A novel “hot spring”-mimetic hydrogel with excellent angiogenic properties for chronic wound healing	223
Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration	213
Extracellular vesicles: A bright star of nanomedicine	209
Microfluidic formulation of nanoparticles for biomedical applications	196
4D-bioprinted silk hydrogels for tissue engineering	186
Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer immunotherapy	185
The regulation of cartilage extracellular matrix homeostasis in joint cartilage degeneration and regeneration	174
Injectable Mussel‐Inspired highly adhesive hydrogel with exosomes for endogenous cell recruitment and cartilage defect regeneration	172
Rapid printing of bio-inspired 3D tissue constructs for skin regeneration	172
Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy	169
Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy	161
Enhanced cancer therapy by hypoxia-responsive copper metal-organic frameworks nanosystem	161
Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors	160
Injectable redox and light responsive MnO2 hybrid hydrogel for simultaneous melanoma therapy and multidrug-resistant bacteria-infected wound healing	159
NIR-II bioimaging of small organic molecule	156
Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice	150
Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy	150
Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy	148

3D bioprinted neural tissue constructs for spinal cord injury repair	148
‘Green’ nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases	139
A versatile nanocomposite based on nanoceria for antibacterial enhancement and protection from aPDT-aggravated inflammation via modulation of macrophage polarization	139
Bioinspired stratified electrowritten fiber-reinforced hydrogel constructs with layer-specific induction capacity for functional osteochondral regeneration	137
Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy	133
Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages	133
Infection microenvironment-related antibacterial nanotherapeutic strategies	130
Exosomes-loaded thermosensitive hydrogels for corneal epithelium and stroma regeneration	128
Hyaluronic acid and chondroitin sulfate (meth)acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation	128
Resolution of inflammation in bone regeneration: From understandings to therapeutic applications	128
Optimized BMSC-derived osteoinductive exosomes immobilized in hierarchical scaffold via lyophilization for bone repair through Bmpr2/Acvr2b competitive receptor-activated Smad pathway	124
Functionalized 3D-printed silk-hydroxyapatite scaffolds for enhanced bone regeneration with innervation and vascularization	123
Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand	123
Intelligent MoS2–CuO heterostructures with multiplexed imaging and remarkably enhanced antitumor efficacy via synergetic photothermal therapy/ chemodynamic therapy/ immunotherapy	123
Infection microenvironment-activated nanoparticles for NIR-II photoacoustic imaging-guided photothermal/chemodynamic synergistic anti-infective therapy	121
Microenvironment-driven sequential ferroptosis, photodynamic therapy, and chemotherapy for targeted breast cancer therapy by a cancer-cell-membrane-coated nanoscale metal-organic framework	119
Cryogel/hydrogel biomaterials and acupuncture combined to promote diabetic skin wound healing through immunomodulation	118
Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges	118
How microbes read the map: Effects of implant topography on bacterial adhesion and biofilm formation	117
NIR-II emissive multifunctional AIEgen with single laser-activated synergistic photodynamic/photothermal therapy of cancers and pathogens	113
Free radicals for cancer theranostics	113
Biomimetic glycopeptide hydrogel coated PCL/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo-immunomodulation	113
Polymeric nanoparticle vaccines to combat emerging and pandemic threats	110
Immunopolarization-regulated 3D printed-electrospun fibrous scaffolds for bone regeneration	106
High-quality milk exosomes as oral drug delivery system	106
Near-infrared-II activated inorganic photothermal nanomedicines	106
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood–brain barrier and attenuates their targeting ability to brain tumor	106
Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration	106
A micro/nano-biomimetic coating on titanium orchestrates osteo/angio-genesis and osteoimmunomodulation for advanced osseointegration	105
Chitosan hydrogel/3D-printed poly(ε‐caprolactone) hybrid scaffold containing synovial mesenchymal stem cells for cartilage regeneration based on tetrahedral framework nucleic acid recruitment	105
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine	104
Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models	103
Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm	102
MSC spheroids-loaded collagen hydrogels simultaneously promote neuronal differentiation and suppress inflammatory reaction through PI3K-Akt signaling pathway	102
Nanobiomaterial-based vaccination immunotherapy of cancer	101
Heparanase-driven sequential released nanoparticles for ferroptosis and tumor microenvironment modulations synergism in breast cancer therapy	101
Skin-inspired gelatin-based flexible bio-electronic hydrogel for wound healing promotion and motion sensing	101
Understanding the role of tissue-specific decellularized spinal cord matrix hydrogel for neural stem/progenitor cell microenvironment reconstruction and spinal cord injury	100
Flexible patch with printable and antibacterial conductive hydrogel electrodes for accelerated wound healing	99
Near-infrared light II - assisted rapid biofilm elimination platform for bone implants at mild temperature	98
3D-printable plant protein-enriched scaffolds for cultivated meat development	98
A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair	97
3D-bioprinted BMSC-laden biomimetic multiphasic scaffolds for efficient repair of osteochondral defects in an osteoarthritic rat model	97
Clodronate-loaded liposomal and fibroblast-derived exosomal hybrid system for enhanced drug delivery to pulmonary fibrosis	97
AIEgens for microbial detection and antimicrobial therapy	95
Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity	95
3D cell-printing of biocompatible and functional meniscus constructs using meniscus‐derived bioink	95
Recent development of metal-organic framework nanocomposites for biomedical applications	95
Cell migration regulated by RGD nanospacing and enhanced under moderate cell adhesion on biomaterials	95
Small molecules combined with collagen hydrogel direct neurogenesis and migration of neural stem cells after spinal cord injury	95

Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity	94
Cancer cell membrane camouflaged iridium complexes functionalized black-titanium nanoparticles for hierarchical-targeted synergistic NIR-II photothermal and sonodynamic therapy	93
A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury	92
Virus-like nanoparticle as a co-delivery system to enhance efficacy of CRISPR/Cas9-based cancer immunotherapy	92
Tough magnesium phosphate-based 3D-printed implants induce bone regeneration in an equine defect model	92
Phenolic immunogenic cell death nanoinducer for sensitizing tumor to PD-1 checkpoint blockade immunotherapy	91
Noninvasively immunogenic sonodynamic therapy with manganese protoporphyrin liposomes against triple-negative breast cancer	91
Injectable immunomodulation-based porous chitosan microspheres/HPCH hydrogel composites as a controlled drug delivery system for osteochondral regeneration	90
Cationization to boost both type I and type II ROS generation for photodynamic therapy	90
Engineering oxygen-deficient ZrO2-x nanoplatform as therapy-activated “immunogenic cell death (ICD)” inducer to synergize photothermal-augmented sonodynamic tumor elimination in NIR-II biological wind	89
A redox-triggered C-centered free radicals nanogenerator for self-enhanced magnetic resonance imaging and chemodynamic therapy	89
Red-light-triggered self-destructive mesoporous silica nanoparticles for cascade-amplifying chemo-photodynamic therapy favoring antitumor immune responses	89
Nanoengineered shear-thinning and bioprintable hydrogel as a versatile platform for biomedical applications	89
Tumor-derived exosomes co-delivering aggregation-induced emission luminogens and proton pump inhibitors for tumor glutamine starvation therapy and enhanced type-I photodynamic therapy	88
Covalent grafting of hyperbranched poly-L-lysine on Ti-based implants achieves dual functions of antibacteria and promoted osteointegration in vivo	88
Injectable hydrogels with high drug loading through B–N coordination and ROS-triggered drug release for efficient treatment of chronic periodontitis in diabetic rats	88
Versatile hollow COF nanospheres via manipulating transferrin corona for precise glioma-targeted drug delivery	88
Aseptic and septic prosthetic joint loosening: Impact of biomaterial wear on immune cell function, inflammation, and infection	87
Injectable ferrimagnetic silk fibroin hydrogel for magnetic hyperthermia ablation of deep tumor	87
Rationally designed rapamycin-encapsulated ZIF-8 nanosystem for overcoming chemotherapy resistance	86
Designer exosomes enabling tumor targeted efficient chemo/gene/photothermal therapy	86
Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants	86
Multifunctional liquid metal-based nanoparticles with glycolysis and mitochondrial metabolism inhibition for tumor photothermal therapy	86
In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury	85
Photo-activated chemo-immunotherapy for metastatic cancer using a synergistic graphene nanosystem	85
Nanofibrous composite aerogel with multi-bioactive and fluid gating characteristics for promoting diabetic wound healing	84
Bioadhesive injectable hydrogel with phenolic carbon quantum dot supported Pd single atom nanozymes as a localized immunomodulation niche for cancer catalytic immunotherapy	84
Tumor microenvironment responsive hollow mesoporous Co9S8@MnO2-ICG/DOX intelligent nanoplatform for synergistically enhanced tumor multimodal therapy	84
Precise magnetic resonance imaging-guided sonodynamic therapy for drug-resistant bacterial deep infection	83
Injectable hydrogel for postoperative synergistic photothermal-chemodynamic tumor and anti-infection therapy	83
High-strength, porous additively manufactured implants with optimized mechanical osseointegration	83
D-arginine-loaded metal-organic frameworks nanoparticles sensitize osteosarcoma to radiotherapy	83
Multi-enzyme mimetic ultrasmall iridium nanozymes as reactive oxygen/nitrogen species scavengers for acute kidney injury management	83
Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration	83
In Vivo-assembled phthalocyanine/albumin supramolecular complexes combined with a hypoxia-activated prodrug for enhanced photodynamic immunotherapy of cancer	82
Large-scale cultured meat production: Trends, challenges and promising biomanufacturing technologies	82
Progress and perspective of microneedle system for anti-cancer drug delivery	81
3D culture of HepaRG cells in GelMa and its application to bioprinting of a multicellular hepatic model	81
Three-dimensional bio-printing of primary human hepatocellular carcinoma for personalized medicine	81
Mononuclear phagocyte system blockade using extracellular vesicles modified with CD47 on membrane surface for myocardial infarction reperfusion injury treatment	80
NIR-II fluorescence imaging guided tumor-specific NIR-II photothermal therapy enhanced by starvation mediated thermal sensitization strategy	80
Intelligent micro-/nanorobots as drug and cell carrier devices for biomedical therapeutic advancement: Promising development opportunities and translational challenges	80
Corn-like Au/Ag nanorod-mediated NIR-II photothermal/photodynamic therapy potentiates immune checkpoint antibody efficacy by reprogramming the cold tumor microenvironment	80
Silk sericin-based materials for biomedical applications	79
Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes	79
Cancer immunogenic cell death via photo-pyroptosis with light-sensitive Indoleamine 2,3-dioxygenase inhibitor conjugate	79
Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration	78
Dual enzyme-mimic nanozyme based on single-atom construction strategy for photothermal-augmented nanocatalytic therapy in the second near-infrared biowindow	78
Dual actions of osteoclastic-inhibition and osteogenic-stimulation through strontium-releasing bioactive nanoscale cement imply biomaterial-enabled osteoporosis therapy	78
Engineered nanomaterials for synergistic photo-immunotherapy	77
3D porous scaffolds from wheat glutenin for cultured meat applications	77
Cerium oxide nanoparticles with antioxidative neurorestoration for ischemic stroke	77
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease	76
CaCO3 nanoparticles incorporated with KAE to enable amplified calcium overload cancer therapy	76
Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia	76
Photocrosslinkable nanocomposite ink for printing strong, biodegradable and bioactive bone graft	76
Leveraging disulfiram to treat cancer: Mechanisms of action, delivery strategies, and treatment regimens	75
Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids	75
Wearable and implantable devices for drug delivery: Applications and challenges	75
A tailored extracellular matrix (ECM) - Mimetic coating for cardiovascular stents by stepwise assembly of hyaluronic acid and recombinant human type III collagen	75
The effect of hypoxia-mimicking responses on improving the regeneration of artificial vascular grafts	74
Biomimetic nanoreactor for targeted cancer starvation therapy and cascade amplificated chemotherapy	74
Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promotes anti-inflammatory polarization of macrophages and bone repair via MAPK/JNK inhibition and OXPHOS activation	74
Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy	74
ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1	74
Multifunctional magnesium incorporated scaffolds by 3D-Printing for comprehensive postsurgical management of osteosarcoma	73
Smart transformable nanomedicines for cancer therapy	73
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling	73
Enhanced chemo-photodynamic therapy of an enzyme-responsive prodrug in bladder cancer patient-derived xenograft models	73
A low-temperature-printed hierarchical porous sponge-like scaffold that promotes cell-material interaction and modulates paracrine activity of MSCs for vascularized bone regeneration	73
A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy	72
Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy	72
Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems	72
Conditioned medium of human bone marrow-derived stem cells promotes tendon-bone healing of the rotator cuff in a rat model	72
Self-assembled hyaluronic acid nanoparticles for osteoarthritis treatment	71
Delivery of manganese carbonyl to the tumor microenvironment using Tumor-Derived exosomes for cancer gas therapy and low dose radiotherapy	71
Nanomedicine progress in thrombolytic therapy	71
Highly dispersed nano-enzyme triggered intracellular catalytic reaction toward cancer specific therapy	70
Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles	70
Injectable biodegradation-visual self-healing citrate hydrogel with high tissue penetration for microenvironment-responsive degradation and local tumor therapy	70

One-for-all phototheranostics: Single component AIE dots as multi-modality theranostic agent for fluorescence-photoacoustic imaging-guided synergistic cancer therapy	70
Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease	70
Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release	70
Multi-functional wound dressings based on silicate bioactive materials	69
Bacterial-based cancer therapy: An emerging toolbox for targeted drug/gene delivery	69
Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods	69
miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype	69
Precision targeting of bacterial pathogen via bi-functional nanozyme activated by biofilm microenvironment	69
Nano-herb medicine and PDT induced synergistic immunotherapy for colon cancer treatment	69
Ruthenium(II) complexes coordinated to graphitic carbon nitride: Oxygen self-sufficient photosensitizers which produce multiple ROS for photodynamic therapy in hypoxia	69
Engineering bioluminescent bacteria to boost photodynamic therapy and systemic anti-tumor immunity for synergistic cancer treatment	68
Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration	68
Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate	68
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia	68
Perfluorocarbon loaded fluorinated covalent organic polymers with effective sonosensitization and tumor hypoxia relief enable synergistic sonodynamic-immunotherapy	68
Targeting and clearance of senescent foamy macrophages and senescent endothelial cells by antibody-functionalized mesoporous silica nanoparticles for alleviating aorta atherosclerosis	68
Active biomaterials for mechanobiology	68
In situ activation of STING pathway with polymeric SN38 for cancer chemoimmunotherapy	67
Tailoring the properties of double-crosslinked emulsion gels using structural design principles: Physical characteristics, stability, and delivery of lycopene	67
Rational collaborative ablation of bacterial biofilms ignited by physical cavitation and concurrent deep antibiotic release	67
Bacteria-derived membrane vesicles to advance targeted photothermal tumor ablation	67
Indoleamine 2,3-dioxygenase (Ido) inhibitors and their nanomedicines for cancer immunotherapy	67
Cell-adaptable dynamic hydrogel reinforced with stem cells improves the functional repair of spinal cord injury by alleviating neuroinflammation	66
Photothermally triggered nitric oxide nanogenerator targeting type IV pili for precise therapy of bacterial infections	66
All-in-one bioactive properties of photothermal nanofibers for accelerating diabetic wound healing	66
Synchronously boosting type-I photodynamic and photothermal efficacies via molecular manipulation for pancreatic cancer theranostics in the NIR-II window	66
Exosomes based strategies for brain drug delivery	66
Dissecting the effects of preconditioning with inflammatory cytokines and hypoxia on the angiogenic potential of mesenchymal stromal cell (MSC)-derived soluble proteins and extracellular vesicles (EVs	65
Chemotherapy-enabled/augmented cascade catalytic tumor-oxidative nanotherapy	65
Co-delivery of dihydroartemisinin and pyropheophorbide-iron elicits ferroptosis to potentiate cancer immunotherapy	65
Construction and performance evaluation of Hep/silk-PLCL composite nanofiber small-caliber artificial blood vessel graft	64
Palmitic acid-modified bovine serum albumin nanoparticles target scavenger receptor-A on activated macrophages to treat rheumatoid arthritis	64
Driving Hierarchical Collagen Fiber Formation for Functional Tendon, Ligament, and Meniscus Replacement	64
Blue light-triggered Fe2+-release from monodispersed ferrihydrite nanoparticles for cancer iron therapy	64
Tumor hypoxia-activated combinatorial nanomedicine triggers systemic antitumor immunity to effectively eradicate advanced breast cancer	63
Liquid exfoliation of ultrasmall zirconium carbide nanodots as a noninflammatory photothermal agent in the treatment of glioma	63
Cancer-specific drug-drug nanoparticles of pro-apoptotic and cathepsin B-cleavable peptide-conjugated doxorubicin for drug-resistant cancer therapy	63
A bionic cellulose nanofiber-based nanocage wound dressing for NIR-triggered multiple synergistic therapy of tumors and infected wounds	63
Conductive polypyrrole-encapsulated silk fibroin fibers for cardiac tissue engineering	63
High-efficient engineering of osteo-callus organoids for rapid bone regeneration within one month	63
Steering cell behavior through mechanobiology in 3D: A regenerative medicine perspective	63
Extracellular matrix scaffold crosslinked with vancomycin for multifunctional antibacterial bone infection therapy	63
Nano-oxygenated hydrogels for locally and permeably hypoxia relieving to heal chronic wounds	63
Oral nanotherapeutics based on Antheraea pernyi silk fibroin for synergistic treatment of ulcerative colitis	62
Engineering of diseased human skin equivalent using 3D cell printing for representing pathophysiological hallmarks of type 2 diabetes in vitro	62
Convergence of 3D printed biomimetic wound dressings and adult stem cell therapy	62
Targeted immunomodulation therapy for cardiac repair by platelet membrane engineering extracellular vesicles via hitching peripheral monocytes	62
Photo-enhanced upcycling H2O2 into hydroxyl radicals by IR780-embedded Fe3O4@MIL-100 for intense nanocatalytic tumor therapy	62
A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@CuS: Photothermal/photodynamic and targeted drug delivery tri-combined therapy for rheumatoid arthritis	62
Polymeric hydrogels as a vitreous replacement strategy in the eye	62
Mutual-reinforcing sonodynamic therapy against Rheumatoid Arthritis based on sparfloxacin sonosensitizer doped concave-cubic rhodium nanozyme	61
Glycogen-based pH and redox sensitive nanoparticles with ginsenoside Rh2 for effective treatment of ulcerative colitis	61
A general in-situ reduction method to prepare core-shell liquid-metal / metal nanoparticles for photothermally enhanced catalytic cancer therapy	61
Controllable assembly/disassembly of polyphenol-DNA nanocomplex for cascade-responsive drug release in cancer cells	61
Rationally designed protein cross-linked hydrogel for bone regeneration via synergistic release of magnesium and zinc ions	61
Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis	61
Tailoring metal-organic frameworks-based nanozymes for bacterial theranostics	61
Implantable multifunctional black phosphorus nanoformulation-deposited biodegradable scaffold for combinational photothermal/ chemotherapy and wound healing	61
TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis	61
Advanced techniques for performing photodynamic therapy in deep-seated tissues	60
Ag2S nanoparticle-mediated multiple ablations reinvigorates the immune response for enhanced cancer photo-immunotherapy	60
An injectable peptide hydrogel with excellent self-healing ability to continuously release salvianolic acid B for myocardial infarction	60
Smart J-aggregate of cyanine photosensitizer with the ability to target tumor and enhance photodynamic therapy efficacy	60
Furin-instructed aggregated gold nanoparticles for re-educating tumor associated macrophages and overcoming breast cancer chemoresistance	60
Enhanced bone regeneration via spatiotemporal and controlled delivery of a genetically engineered BMP-2 in a composite Hydrogel	59
Diabetes immunity-modulated multifunctional hydrogel with cascade enzyme catalytic activity for bacterial wound treatment	59
Self-delivery oxidative stress amplifier for chemotherapy sensitized immunotherapy	59
Self-assembled AIEgen nanoparticles for multiscale NIR-II vascular imaging	59
Strategies to improve meat-like properties of meat analogs meeting consumers’ expectations	59
Immunomodulatory strategies for bone regeneration: A review from the perspective of disease types	58
A multifunctional hydrogel coating to direct fibroblast activation and infected wound healing via simultaneously controllable photobiomodulation and photodynamic therapies	58
Versatile metal-phenolic network nanoparticles for multitargeted combination therapy and magnetic resonance tracing in glioblastoma	58
Biomimetic co-assembled nanodrug of doxorubicin and berberine suppresses chemotherapy-exacerbated breast cancer metastasis	58
Hydrogel mechanics are a key driver of bone formation by mesenchymal stromal cell spheroids	58
In-silico investigation of umami peptides with receptor T1R1/T1R3 for the discovering potential targets: A combined modeling approach	58
Multistage-responsive clustered nanosystem to improve tumor accumulation and penetration for photothermal/enhanced radiation synergistic therapy	58
An orthobiologics-free strategy for synergistic photocatalytic antibacterial and osseointegration	57
Enzymatical biomineralization of DNA nanoflowers mediated by manganese ions for tumor site activated magnetic resonance imaging	57
AIEgen-loaded nanofibrous membrane as photodynamic/photothermal antimicrobial surface for sunlight-triggered bioprotection	57
Organ-on-a-chip model of vascularized human bone marrow niches	56
Snail-inspired AFG/GelMA hydrogel accelerates diabetic wound healing via inflammatory cytokines suppression and macrophage polarization	56
A host-coupling bio-nanogenerator for electrically stimulated osteogenesis	56
Carbon dots nanophotosensitizers with tunable reactive oxygen species generation for mitochondrion-targeted type I/II photodynamic therapy	56
Structure remodeling of soy protein-derived amyloid fibrils mediated by epigallocatechin-3-gallate	56
Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy	56
IL-12 nanochaperone-engineered CAR T cell for robust tumor-immunotherapy	56
Carbon fiber reinforced polymers for implantable medical devices	55
In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift	55
Fusion peptide engineered “statically-versatile” titanium implant simultaneously enhancing anti-infection, vascularization and osseointegration	55
Mussel patterned with 4D biodegrading elastomer durably recruits regenerative macrophages to promote regeneration of craniofacial bone	55
Controllable ligand spacing stimulates cellular mechanotransduction and promotes stem cell osteogenic differentiation on soft hydrogels	54
Shedding light on 3D printing: Printing photo-crosslinkable constructs for tissue engineering	54
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis	54
Zn0.8Li0.1Sr—a biodegradable metal with high mechanical strength comparable to pure Ti for the treatment of osteoporotic bone fractures: In vitro and in vivo studies	54
Self-assembling multidomain peptide hydrogels accelerate peripheral nerve regeneration after crush injury	54