OOIR: Observatory of International Research

Papers

(The H4-Index of Biomaterials is 82. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Editorial Board	269
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models	264
Systemically administered platelet-inspired nanoparticles to reduce inflammation surrounding intracortical microelectrodes	231
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect	225
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation	224
Corrigendum to ‘Optimal electrical stimulation boosts stem cell therapy in nerve regeneration’ [Biomaterials 181 (2018) 18758]	223
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment	213
Gradient-driven deep penetration of self-electrophoretic nanoparticles in acidic tumor microenvironments for enhanced antitumor therapy	191
Selective recognition of bacterial phospholipids by antimicrobial peptides: Employing a host-guest-mediated competitive inhibition strategy	170
Unlocking the therapeutic potential of tumor-derived small extracellular vesicles in cancer immunotherapy: A multifaceted approach	166
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment	146
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters	142
Gut-confined fullerene reprograms lactate metabolism to Rescue hypoxia-induced exercise intolerance	139
Nanoarchitectonics of penetrating peptide and anionic amphiphiles for dental plaque eradication	136
Ultrasound-orchestrated collapse of cancer stem cell niches through synergistic physical barrier disruption and intracellular homeostasis reprogramming	136
An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis	135
Self-sustained biomimetic bioelectronic accelerated metabolic reprogramming of bone regeneration	134
Multifunctional copper-light synergistic prodrug nanosystems for specific reprogramming of tumour immunogenic endoplasmic reticulum stress	131
Mitocytosis-inducing nanoparticles alleviate gemcitabine resistance via dual disruption of pyrimidine synthesis and redox homeostasis in pancreatic ductal adenocarcinoma	128
Hepatic endoplasmic reticulum-derived nanodiscs for broad-spectrum drug detoxification	128
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment	120
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization	120
Target anesthesia and surgery induced senescent cell via composite microsphere hydrogels as nose-to-brain amplifiers of platelet factor 4 delivery for neurocognitive dysfunction repair	120
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model	120
Inhalable DNase I@Au hybrid nanoparticles for radiation sensitization and metastasis inhibition by elimination of neutrophil extracellular traps	118

Biomimetic nanostructural materials based on placental amniotic membrane-derived nanofibers for self-healing and anti-adhesion during cesarean section	117
Micro/nanomotors for biofilm remediation: Nanoarchitectonic breakthroughs with a focus on regulatory and clinical translation challenges	116
FAK modulates immune response and fibroblast activation in biomaterial-induced fibrosis	114
Click-crosslinked nanogels integrated into 3D stem cell spheroids enhance regenerative function for swallowing muscle repair	113
Engineered micro-structured biomimetic material for modelling the outer blood-retinal barrier	113
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX	110
Selenium-albumin corona rinse ameliorates diabetic periodontitis by inhibiting inflammation, anti-bacterial and improving osteogenesis via activating TrxR1/ROS/β-catenin anti-oxidation cascade	110
Nanomaterial-based strategies for anti-aging and regeneration in oral and maxillofacial tissues: Mechanisms and applications	109
Biomimetic cascade “four-in-one” Nanozyme for remodeling the redox tumor microenvironment and disrupting energy homeostasis to enhance ferroptosis against triple-negative breast cancer	109
Short-chain dense brush PEGylation on rigid nanocarriers overcomes anti-PEG antibody recognition for immune-stealth drug delivery	108
Multifunctional hollow manganese silicate nanoparticles for the treatment of acute lung injury and Pseudomonas aeruginosa pulmonary infection	108
Potentiating the effect of immunotherapy in pancreatic cancer using gas-entrapping materials	108
In vivo efficacy of an injectable piezoelectric nanocomposite hydrogel and low-intensity pulsed ultrasound in two preclinical models of osteoarthritis	108
Chiral gold nanoparticle synergizes immunometabolic crosstalk and metabolism remodeling for diabetic wound healing	107
A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces	107
Vacancies-rich Z-scheme VdW heterojunction as H2S-sensitized synergistic therapeutic nanoplatform against refractory biofilm infections	106
An antioxidative injectable chitosan hydrogel based on tannic acid modified dialdehyde polyurethane nano-crosslinker targeting RIPK1 to regulate neuroinflammation for amelioration of Parkinson's disea	105
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy	104
3D perfusable minichannels stented with matrix bound vesicles derived from gingival mesenchymal stem cells ameliorated granuloma-related stenosis and improved survival in a rabbit tracheal replacement	101
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair	101
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine	101
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice	101
Gel@CAT-L hydrogel mediates mitochondrial unfolded protein response to regulate reactive oxygen species and mitochondrial homeostasis in osteoarthritis	100
Investigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery	100
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p	96
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration	96
Tailoring extracellular matrix niches: Impact of glycosaminoglycan content on multiple differentiation of human mesenchymal stem cells	96
A rationally designed polypeptide-based hybrid platform for targeted intranasal brain drug delivery	95
Smearable CQD-entrapped hydrogel with sensitive pH response and photodynamic antibacterial properties for visual intelligent wound monitoring	94
Modulating the oral microbiome with dental biomaterials: A review of challenges, advances, and future perspectives	94
A comparative study assessing neural recording quality and inflammatory tissue response between stiff and flexible microelectrode arrays	93
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer	93
Bio-orthogonal-labeled exosomes reveals specific distribution in vivo and provides potential application in ARDS therapy	93
Fusogenic liposomes encapsulating mitochondria as a promising delivery system for osteoarthritis therapy	92
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain	91
Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy	90
Amplification of cGAS-STING pathway with “single-molecule multitarget” nanoparticles for chemo-immunotherapy of ovarian cancer	90
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model	90
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis	89
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy	89
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia	87
Metal-polyphenol nanocomposite hybrid hydrogel: A multifunctional platform for treating diabetic foot ulcers through metabolic microenvironment reprogramming	86
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors	86
Breast implant silicone exposure induces immunogenic response and autoimmune markers in human periprosthetic tissue	86
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage	85
Editorial Board	84
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor	84
Editorial Board	84
A low-energy emulsification platform based on a Diet Coke–Mentos reaction-derived bubbly flow for formulating various emulsions as drug carriers	84
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain	84

Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses	83
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair	83
Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy	83
Photoactivated in-situ engineered-bacteria as an efficient H2S generator to enhance photodynamic immunotherapy via remodeling the tumor microenvironment	83
Therapeutic potential of urinary extracellular vesicles in delivering functional proteins and modulating gene expression for genetic kidney disease	82
Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells	82
Corrigendum to ‘Bioprinting 3D microfibrous scaffolds for engineering cardiac tissues and heart-on-a-chip’ [Biomaterials Volume 110, (2016) Pages 45–59]	82
Bone marrow adipocytes in cancer: Mechanisms, models, and therapeutic implications	82
Heteroantigen-assembled nanovaccine enhances the polyfunctionality of TILs against tumor growth and metastasis	82