OOIR: Observatory of International Research

Papers

(The H4-Index of Biomaterials is 87. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment	724
Editorial Board	363
Editorial Board	311
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer	307
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters	249
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain	226
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models	221
Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy	203
A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces	185
Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy	184
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model	182
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps	176
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy	173
Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia	170
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy	159
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors	156
Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance	154
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization	147
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX	146
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain	142
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment	138
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect	137
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment	134
Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment	133
Engineered micro-structured biomimetic material for modelling the outer blood-retinal barrier	133

The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model	129
Two-dimensional nanomaterials-added dynamism in 3D printing and bioprinting of biomedical platforms: Unique opportunities and challenges	129
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy	128
Fusogenic liposomes encapsulating mitochondria as a promising delivery system for osteoarthritis therapy	127
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease	127
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage	126
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration	125
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice	124
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p	121
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation	120
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia	120
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine	119
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis	119
Mitochondria-targeting materials and therapies for regenerative engineering	118
Insensitivity of dental pulp stem cells migration to substrate stiffness	117
Cr(V)–Cr(III) in-situ transition promotes ROS generation to achieve efficient cancer therapy	115
Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist	114
Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration	113
Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy	110
Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases	108
Both non-coated and polyelectrolytically-coated intraocular collagen-alginate composite gels enhanced photoreceptor survival in retinal degeneration	105
Effect of carbon nanomaterial dimension on the functional activity and degeneration of neurons	105
Biomaterial based implants caused remote liver fatty deposition through activated blood-derived macrophages	105
Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury	104
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor	104
Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells	104
Editorial Board	103
Polymeric nanoparticle gel for intracellular mRNA delivery and immunological reprogramming of tumors	103
Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses	102
Cryogel vaccines effectively induce immune responses independent of proximity to the draining lymph nodes	102
Suspension culture of human induced pluripotent stem cell-derived intestinal organoids using natural polysaccharides	101
Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells	101
Engineering a 3D collective cancer invasion model with control over collagen fiber alignment	100
Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse	99
Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells	99
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy	99
Shape memory micro-anchors with magnetic guidance for precision micro-vascular deployment	97
Heteroantigen-assembled nanovaccine enhances the polyfunctionality of TILs against tumor growth and metastasis	97
Retraction notice to “Phototherapy together with it triggered immunological response for Anti-HPV treatment of oropharyngeal cancer: Removing tumor and pathogenic virus simultaneously” [Biomaterials (	97
Editorial Board	95
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis	95
Editorial Board	94
Nano-enabled photosynthesis in tumours to activate lipid peroxidation for overcoming cancer resistances	94
A low-energy emulsification platform based on a Diet Coke–Mentos reaction-derived bubbly flow for formulating various emulsions as drug carriers	93
Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections	93
Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma	93
Activation of the cGAS-STING pathway combined with CRISPR-Cas9 gene editing triggering long-term immunotherapy	93
Self-preparation system using glucose oxidase-inspired nitroreductase amplification for cascade-responsive drug release and multidrug resistance reversion	92
“One-stitch” bioorthogonal prodrug activation based on cross-linked lipoic acid nanocapsules	92
Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood	91

Rationally integrating peptide-induced targeting and multimodal therapies in a dual-shell theranostic platform for orthotopic metastatic spinal tumors	91
Inhalable pH-responsive DNA tetrahedron nanoplatform for boosting anti-tumor immune responses against metastatic lung cancer	90
Evaluation of immobilized microspheres of Clonostachys rosea on Botrytis cinerea and tomato seedlings	90
Remodeling liver microenvironment by L-arginine loaded hollow polydopamine nanoparticles for liver cirrhosis treatment	90
Wake biofilm up to enhance suicidal uptake of gallium for chronic lung infection treatment	89
Oxygen-vacancy-rich molybdenum carbide MXene nanonetworks for ultrasound-triggered and capturing-enhanced sonocatalytic bacteria eradication	89
Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states	88
Injectable and photocurable CAR-T cell formulation enhances the anti-tumor activity to melanoma in mice	88
Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices	88
Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome	87
Graphene oxide-functionalized nanocomposites promote osteogenesis of human mesenchymal stem cells via enhancement of BMP-SMAD1/5 signaling pathway	87
A physicochemical double cross-linked multifunctional hydrogel for dynamic burn wound healing: shape adaptability, injectable self-healing property and enhanced adhesion	87
AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery	87