OOIR: Observatory of International Research

Papers

(The H4-Index of Biomaterials is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Bio-orthogonal-labeled exosomes reveals specific distribution in vivo and provides potential application in ARDS therapy	539
Engineered micro-structured biomimetic material for modelling the outer blood-retinal barrier	253
Editorial Board	245
Editorial Board	241
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models	212
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment	212
Chiral gold nanoparticle synergizes immunometabolic crosstalk and metabolism remodeling for diabetic wound healing	208
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors	207
Nanomaterial-based strategies for anti-aging and regeneration in oral and maxillofacial tissues: Mechanisms and applications	202
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment	196
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain	183
Unlocking the therapeutic potential of tumor-derived small extracellular vesicles in cancer immunotherapy: A multifaceted approach	175
Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment	163
Gradient-driven deep penetration of self-electrophoretic nanoparticles in acidic tumor microenvironments for enhanced antitumor therapy	155
Selective recognition of bacterial phospholipids by antimicrobial peptides: Employing a host-guest-mediated competitive inhibition strategy	153
3D perfusable minichannels stented with matrix bound vesicles derived from gingival mesenchymal stem cells ameliorated granuloma-related stenosis and improved survival in a rabbit tracheal replacement	143
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage	140
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy	138
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis	134
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration	131
Vacancies-rich Z-scheme VdW heterojunction as H2S-sensitized synergistic therapeutic nanoplatform against refractory biofilm infections	129
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice	129
Gel@CAT-L hydrogel mediates mitochondrial unfolded protein response to regulate reactive oxygen species and mitochondrial homeostasis in osteoarthritis	126
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain	124
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps	124

A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces	123
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy	118
Fusogenic liposomes encapsulating mitochondria as a promising delivery system for osteoarthritis therapy	113
Target anesthesia and surgery induced senescent cell via composite microsphere hydrogels as nose-to-brain amplifiers of platelet factor 4 delivery for neurocognitive dysfunction repair	113
Systemically administered platelet-inspired nanoparticles to reduce inflammation surrounding intracortical microelectrodes	112
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect	111
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer	111
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation	110
Selenium-albumin corona rinse ameliorates diabetic periodontitis by inhibiting inflammation, anti-bacterial and improving osteogenesis via activating TrxR1/ROS/β-catenin anti-oxidation cascade	109
Biomimetic nanostructural materials based on placental amniotic membrane-derived nanofibers for self-healing and anti-adhesion during cesarean section	107
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model	106
Inhalable DNase I@Au hybrid nanoparticles for radiation sensitization and metastasis inhibition by elimination of neutrophil extracellular traps	106
Breast implant silicone exposure induces immunogenic response and autoimmune markers in human periprosthetic tissue	105
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment	104
Amplification of cGAS-STING pathway with “single-molecule multitarget” nanoparticles for chemo-immunotherapy of ovarian cancer	102
Corrigendum to ‘Optimal electrical stimulation boosts stem cell therapy in nerve regeneration’ [Biomaterials 181 (2018) 18758]	102
Short-chain dense brush PEGylation on rigid nanocarriers overcomes anti-PEG antibody recognition for immune-stealth drug delivery	101
Multifunctional hollow manganese silicate nanoparticles for the treatment of acute lung injury and Pseudomonas aeruginosa pulmonary infection	101
A comparative study assessing neural recording quality and inflammatory tissue response between stiff and flexible microelectrode arrays	99
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters	98
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX	98
Potentiating the effect of immunotherapy in pancreatic cancer using gas-entrapping materials	97
Investigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery	96
Tailoring extracellular matrix niches: Impact of glycosaminoglycan content on multiple differentiation of human mesenchymal stem cells	95
An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis	95
Self-sustained biomimetic bioelectronic accelerated metabolic reprogramming of bone regeneration	93
Modulating the oral microbiome with dental biomaterials: A review of challenges, advances, and future perspectives	92
Multifunctional copper-light synergistic prodrug nanosystems for specific reprogramming of tumour immunogenic endoplasmic reticulum stress	92
Mitocytosis-inducing nanoparticles alleviate gemcitabine resistance via dual disruption of pyrimidine synthesis and redox homeostasis in pancreatic ductal adenocarcinoma	92
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair	92
An antioxidative injectable chitosan hydrogel based on tannic acid modified dialdehyde polyurethane nano-crosslinker targeting RIPK1 to regulate neuroinflammation for amelioration of Parkinson's disea	92
Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy	91
Hepatic endoplasmic reticulum-derived nanodiscs for broad-spectrum drug detoxification	90
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization	90
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia	90
Smearable CQD-entrapped hydrogel with sensitive pH response and photodynamic antibacterial properties for visual intelligent wound monitoring	90
A rationally designed polypeptide-based hybrid platform for targeted intranasal brain drug delivery	90
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p	89
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model	89
In vivo efficacy of an injectable piezoelectric nanocomposite hydrogel and low-intensity pulsed ultrasound in two preclinical models of osteoarthritis	89
Micro/nanomotors for biofilm remediation: Nanoarchitectonic breakthroughs with a focus on regulatory and clinical translation challenges	89
Ala-Ce@Ce6 Hybrid Supramolecular Nanozyme for Oxygen Self-supplying Hypoxia Photodynamic Therapy	89
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine	88
Metal-polyphenol nanocomposite hybrid hydrogel: A multifunctional platform for treating diabetic foot ulcers through metabolic microenvironment reprogramming	88
Editorial Board	87
Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury	87
Editorial Board	86
Oxygen-vacancy-rich molybdenum carbide MXene nanonetworks for ultrasound-triggered and capturing-enhanced sonocatalytic bacteria eradication	86
Suspension culture of human induced pluripotent stem cell-derived intestinal organoids using natural polysaccharides	86
Nano-enabled photosynthesis in tumours to activate lipid peroxidation for overcoming cancer resistances	86

Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse	85
Evaluation of immobilized microspheres of Clonostachys rosea on Botrytis cinerea and tomato seedlings	85
Mo2C nanozyme targets citrate synthase to treat acute kidney injury through alleviating oxidative stress and dysfunction of energy metabolism	81
A low-energy emulsification platform based on a Diet Coke–Mentos reaction-derived bubbly flow for formulating various emulsions as drug carriers	80
Advanced biomaterial-based strategies for craniofacial bone regeneration	80
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor	80
Engineering adeno-associated viral vectors for CRISPR/Cas based in vivo therapeutic genome editing	80