OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology Letters is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Surfactants: physicochemical interactions with biological macromolecules	88
Superoxide dismutase as multipotent therapeutic antioxidant enzyme: Role in human diseases	49
Biosynthesis of magnetic iron oxide nanoparticles: a review	38
Soil amendment in plastic greenhouse using modified biochar: soil bacterial diversity responses and microbial biomass carbon and nitrogen	29
Co-delivery of miRNA-15a and miRNA-16–1 using cationic PEGylated niosomes downregulates Bcl-2 and induces apoptosis in prostate cancer cells	29
Current trends in biopharmaceuticals production in Escherichia coli	28
Microbial fuel cell biosensor for the determination of biochemical oxygen demand of wastewater samples containing readily and slowly biodegradable organics	27
Kinetic characterization of purified laccase from Trametes hirsuta: a study on laccase catalyzed biotransformation of 1,4-dioxane	26
Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applications	25
Low-quality animal by-product streams for the production of PHA-biopolymers: fats, fat/protein-emulsions and materials with high ash content as low-cost feedstocks	23
Autophagy induced by Schwann cell-derived exosomes promotes recovery after spinal cord injury in rats	23
Terpenoid indole alkaloid biosynthesis in Catharanthus roseus: effects and prospects of environmental factors in metabolic engineering	22
Bacillus subtilis CtpxS2-1 induces systemic resistance against anthracnose in Andean lupin by lipopeptide production	21
Biological synthesis of nicotinamide mononucleotide	21
Plant-derived VLP: a worthy platform to produce vaccine against SARS-CoV-2	21
Kinetic models of biological hydrogen production by Enterobacter aerogenes	20
Circ_0114876 promoted IL-1β-induced chondrocyte injury by targeting miR-671/TRAF2 axis	19
Improved AP-3 production through combined ARTP mutagenesis, fermentation optimization, and subsequent genome shuffling	18
Transcriptome expression profiles reveal response mechanisms to drought and drought-stress mitigation mechanisms by exogenous glycine betaine in maize	18
Multiple gene integration to promote erythritol production on glycerol in Yarrowia lipolytica	18
Valorization of sugar beet pulp through biotechnological approaches: recent developments	17
Antifungal action of chitosan in combination with fungicides in vitro and chitosan conjugate with gallic acid on tomatoes against Botrytis cinerea	17
Biosynthetic process and strain improvement approaches for industrial penicillin production	17
Bacterial type VI secretion system (T6SS): an evolved molecular weapon with diverse functionality	16
Influence of 16S rRNA reference databases in amplicon-based environmental microbiome research	16

One-step purification and immobilization of recombinant proteins using SpyTag/SpyCatcher chemistry	16
Identification of the PP2C gene family in paper mulberry (Broussonetia papyrifera) and its roles in the regulation mechanism of the response to cold stress	16
Optimization of activated charcoal detoxification and concentration of chestnut shell hydrolysate for xylitol production	15
Response surface statistical optimization of fermentation parameters for resveratrol production by the endophytic fungus Arcopilus aureus and its tyrosinase inhibitory activity	15
Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors	14
Antifungal effects of lycorine on Botrytis cinerea and possible mechanisms	14
Three-dimensional tissue fabrication system by co-culture of microalgae and animal cells for production of thicker and healthy cultured food	14
Circ_0001247 functions as a miR-1270 sponge to accelerate cervical cancer progression by up-regulating ZEB2 expression level	14
RETRACTED ARTICLE: Characterization of a new bacteriocin-like inhibitory peptide produced by Lactobacillus sakei B-RKM 0559	13
In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes	13
Simultaneous saccharification and lactic acid fermentation of the cellulosic fraction of municipal solid waste using Bacillus smithii	13
Evaluation of hepatic drug-metabolism for glioblastoma using liver-brain chip	13
Improvement of tacrolimus production in Streptomyces tsukubaensis by mutagenesis and optimization of fermentation medium using Plackett–Burman design combined with response surface methodology	13
Preparation, purification, and characterization of low-molecular-weight hyaluronic acid	13
Combination of atmospheric and room temperature plasma (ARTP) mutagenesis, genome shuffling and dimethyl sulfoxide (DMSO) feeding to improve FK506 production in Streptomyces tsukubaensis	13
Tea polyphenols-loaded nanocarriers: preparation technology and biological function	12
The carbon partitioning of glucose and DIC in mixotrophic, heterotrophic and photoautotrophic cultures of Tetraselmis suecica	12
Characterization and comparative genomic analysis of gamma-aminobutyric acid (GABA)-producing lactic acid bacteria from Thai fermented foods	12
Evolution and expression analysis of CDPK genes under drought stress in two varieties of potato	12
Larvicidal activity against Aedes aegypti and molecular docking studies of compounds extracted from the endophytic fungus Aspergillus sp. isolated from Bertholletia excelsa Humn. & Bonpl	12
Bone marrow mesenchymal stem cell-derived exosomes loaded with miR-26a through the novel immunomodulatory peptide DP7-C can promote osteogenesis	12
Establishment and optimization of a high-throughput mimic perfusion model in ambr® 15	12
Enhancement of cordycepin production from Cordyceps militaris culture by epigenetic modification	12
Furfural biotransformation in Acinetobacter baylyi ADP1 and Acinetobacter schindleri ACE	11
Transferosomes stabilized hydrogel incorporated rhodomyrtone-rich extract from Rhodomyrtus tomentosa leaf fortified with phosphatidylcholine for the management of skin and soft-tissue infections	11
In vivo delivery of a multiepitope peptide and Nef protein using novel cell-penetrating peptides for development of HIV-1 vaccine candidate	11
Surface charge engineering of Thermomyces lanuginosus lipase improves enzymatic activity and biodiesel synthesis	11
MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway	11
Lipopeptide production by Bacillus atrophaeus strain B44 and its biocontrol efficacy against cotton rhizoctoniosis	11
3D reconstruction and morphological analysis of electrostimulated hyperthermophile biofilms of Thermotoga neapolitana	11
Bluemomycin, a new naphthoquinone derivative from Streptomyces sp. with antimicrobial and cytotoxic properties	11
Evaluation of hypoglycemic therapeutics and nutritional supplementation for type 2 diabetes mellitus management: An insight on molecular approaches	10
Organic materials with high C/N ratio: more beneficial to soil improvement and soil health	10
Nitrate modulation of Bacillus sp. biofilm components: a proposed model for sustainable bioremediation	10
Detection of homologous recombination events in SARS-CoV-2	10
Obtaining hemicellulosic hydrolysate from sugarcane bagasse for microbial oil production by Lipomyces starkeyi	10
Bufalin inhibits the malignant development of non-small cell lung cancer by mediating the circ_0046264/miR-522-3p axis	10
Production of sesquiterpene patchoulol in mitochondrion-engineered Saccharomyces cerevisiae	10
Characterization and inhibition of four fungi producing citrinin in various culture media	9
Food-grade γ-aminobutyric acid production by immobilized glutamate decarboxylase from Lactobacillus plantarum in rice vinegar and monosodium glutamate system	9
De novo biosynthesis of 2′-fucosyllactose in engineered Pichia pastoris	9
The potential of extracellular biopolymer production by Mesorhizobium sp. from monosaccharide constituents of lignocellulosic biomass	9
Characterization of a thermostable and solvent-tolerant laccase produced by Streptomyces sp. LAO	9
Characterization and engineering of two new GH9 and GH48 cellulases from a Bacillus pumilus isolated from Lake Bogoria	9
Carbohydrate analysis of Mortierella alpina by colorimetry and HPLC–ELSD to reveal accumulation differences of sugar and lipid	9
Knock out of sHSP genes determines some modifications in the probiotic attitude of Lactiplantibacillus plantarum	8
Promoter engineering for high ectoine production in a lower saline medium by Halomonas hydrothermalis Y2	8
Uncoupling glucose sensing from GAL metabolism for heterologous lactose fermentation in Saccharomyces cerevisiae	8
Fusarium solani G6, a novel vitexin-producing endophytic fungus: characterization, yield improvement and osteoblastic proliferation activity	8
Production of 1,3-propanediol and lactic acid from crude glycerol by a microbial consortium from intertidal sludge	8

Simultaneous accumulation of astaxanthin and β-carotene in Chlamydomonas reinhardtii by the introduction of foreign β-carotene hydroxylase gene in response to high light stress	8
Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells	8
Production and characterization of a novel, thermotolerant fungal phytase from agro-industrial byproducts for cattle feed	8
Prospects of antimicrobial peptides as an alternative to chemical preservatives for food safety	8
Application of exogenous melatonin in vitro and in planta: a review of its effects and mechanisms of action	8
A gold nanoparticles-based lateral flow assay utilizing baculovirus expressed recombinant nucleocapsid and receptor binding domain proteins for serodetection of IgG and IgM against SARS-CoV-2	7
Anti-inflammatory potential of baicalein combined with silk fibroin protein in a zebrafish model (Danio rerio)	7
Synthesis of novel nicotinamide susbstituted phthalocyanine and photodynamic antomicrobial chemotherapy evaluation potentiated by potassium iodide against the gram positive S. aureus and gram negative	7
Synthesis of nano hydroxyapatite from Hypopthalmichthys molitrix (silver carp) bone waste by two different methods: a comparative biophysical and in vitro evaluation on osteoblast MG63 cell lines	7
The construction of a dual-functional strain that produces both polysaccharides and sulfotransferases	7
Continuous production of fructooligosaccharides by recycling of the thermal-stable β-fructofuranosidase produced by Aspergillus niger	7
Polymeric nanoparticles for DNA vaccine-based cancer immunotherapy: a review	7
Current advances and future prospects in production of recombinant insulin and other proteins to treat diabetes mellitus	7
Role of the mitochondrial citrate-oxoglutarate carrier in lipid accumulation in the oleaginous fungus Mortierella alpina	7
Characterization of Lactobacillus reuteri WQ-Y1 with the ciprofloxacin degradation ability	7
Stem cells or their exosomes: which is preferred in COVID-19 treatment?	7
Candida rugosa lipase immobilized on hydrophobic support Accurel MP 1000 in the synthesis of emollient esters	7
Archaeal and bacterial community structures of rural household biogas digesters with different raw materials in Qinghai Plateau	7
Eustigmatophyte strains with potential interest in cancer prevention and treatment: partial chemical characterization and evaluation of cytotoxic and antioxidant activity	7
Enhanced β-carotene production by overexpressing the DID2 gene, a subunit of ESCRT complex, in engineered Yarrowia lipolytica	7
Three-dimensional cell culture (3DCC) improves secretion of signaling molecules of mesenchymal stem cells (MSCs)	7
Immobilization of Baeyer–Villiger monooxygenase from acetone grown Fusarium sp.	7
Biochemical characterization of xylanase GH11 isolated from Aspergillus niger BCC14405 (XylB) and its application in xylooligosaccharide production	7
Engineering a heterologous synthetic pathway in Escherichia coli for efficient production of biotin	7
High-cell-density fed-batch cultivations of Vibrio natriegens	6
Designed protein multimerization and polymerization for functionalization of proteins	6
Exploring potential bacterial populations for enhanced anthraquinone dyes biodegradation: a critical review	6
Citrus essential oil: would it be feasible as antimicrobial in the bioethanol industry?	6
Heterologous expression and biochemical characterization of a cold-active lipase from Rhizopus microsporus suitable for oleate synthesis and bread making	6
Circular RNA 0081146 facilitates the progression of gastric cancer by sponging miR-144 and up-regulating HMGB1	6
Suspension state regulates epithelial-to-mesenchymal transition and stemness of breast tumor cells	6
Effect of lactic acid bacteria on the structure and potential function of the microbial community of Nongxiangxing Daqu	6
Antigenic and conserved peptides from diverse Helicobacter pylori antigens	6
The dilution effect of media culture on mixing time, Kla O2, and hyaluronic acid production in S. zooepidemicus fed-batch culture	6
Comparative transcriptome analysis of the fungus Gibberella zeae transforming lithocholic acid into ursodeoxycholic acid	6
Box–Behnken design optimisation of a green novel nanobio-based reagent for rapid visualisation of latent fingerprints on wet, non-porous substrates	6
Infected insect gut reveals differentially expressed proteins for cellular redox, metal resistance and secretion system in Yersinia enterocolitica-Helicoverpa armigera pathogenic model	6
Overexpression of uracil permease and nucleoside transporter from Bacillus amyloliquefaciens improves cytidine production in Escherichia coli	6
Growth of Leucoagaricus gongylophorus Möller (Singer) and production of key enzymes in submerged and solid-state cultures with lignocellulosic substrates	6
Roles of PKAc1 and CRE1 in cellulose degradation, conidiation, and yellow pigment synthesis in Trichoderma reesei QM6a	6
Mesenchymal stem cells for the treatment of cognitive impairment caused by neurological diseases	6
Production of flavonol and flavone 6-C-glucosides by bioconversion in Escherichia coli expressing a C-glucosyltransferase from wasabi (Eutrema japonicum)	6
Construction of actinomycetes complex flora in degrading corn straw and an evaluation of their degradative effects	6
Comparative transcriptome analysis reveals the regulation network for fiber strength in cotton	6
Enhancement of riboflavin production in Bacillus subtilis via in vitro and in vivo metabolic engineering of pentose phosphate pathway	5
Perspectives of nervonic acid production by Yarrowia lipolytica	5
Application of the modified cytosine base-editing in the cultured cells of bama minipig	5
Efficient production of l-menthyl α-glucopyranoside from l-menthol via whole-cell biotransformation using recombinant Escherichia coli	5
Enhanced soluble expression of active recombinant human interleukin-29 using champion pET SUMO system	5
Quantitative proteomics implicates YggT in streptomycin resistance in Salmonella enterica serovar Enteritidis	5
Expression of recombinant protease MarP from Mycobacterium tuberculosis in Pichia pastoris and its effect on human monocytes	5
Microbial bioconversion of feathers into antioxidant peptides and pigments and their liposome encapsulation	5
Engineering synthetic microbial consortium for cadaverine biosynthesis from glycerol	5
Recent advances and current challenges in CAR-T cell therapy	5
A novel recombinant protein vaccine containing the different E7 proteins of the HPV16, 18, 6, 11 E7 linked to the HIV-1 Tat (47–57) improve cytotoxic immune responses	5
Oligo replication advantage driven by GC content and Gibbs free energy	5
Improving the specific activity and stability of alkaline pectinase PEL3 through SpyTag/SpyCatcher cyclization	5
High efficiency sorting and outgrowth for single-cell cloning of mammalian cell lines	5
In vitro facilitating role of polygonatum sibiricum polysaccharide in osteogenic differentiation of bone marrow mesenchymal stem cells from patients with multiple myeloma	5
Expression of l-phosphinothricin synthesis enzymes in Pichia pastoris for synthesis of l-phosphinothricin	5
Invigorating chronic wound healing by nanocomposites composed with bioactive materials: a comprehensive review	5
A brief period of darkness induces changes in fatty acid biosynthesis towards accumulation of saturated fatty acids in Chlorella vulgaris UMT-M1 at stationary growth phase	5
Efficient immobilization behavior and mechanism investigation of Pb(II) by Aspergillus tubingensis	5
Strategy to reduce acetic acid in sugarcane bagasse hemicellulose hydrolysate concomitantly with xylitol production by the promising yeast Cyberlindnera xylosilytica in a bioreactor	5
miR-19a mitigates hypoxia/reoxygenation-induced injury by depressing CCL20 and inactivating MAPK pathway in human embryonic cardiomyocytes	5
CD44 mediates hyaluronan to promote the differentiation of human amniotic mesenchymal stem cells into chondrocytes	5
Statistical optimization of thermostable alkaline protease from Bacillus cereus KM 05 using response surface methodology	5
5-Aminolevulinic acid level and dye-decolorizing peroxidase expression regulate heme synthesis in Escherichia coli	5
Toxicity and preventive approaches of Fusarium derived mycotoxins using lactic acid bacteria: state of the art	5
Biogenesis and characterization of proficient silver nanoparticles employing marine procured fungi Hamigera pallida and assessment of their antioxidative, antimicrobial and anticancer potency	5
Serum-derived exosomes accelerate scald wound healing in mice by optimizing cellular functions and promoting Akt phosphorylation	5
Modification of an engineered Escherichia coli by a combinatorial strategy to improve 3,4-dihydroxybutyric acid production	5
Novel CRISPR/Cas9-mediated knockout of LIG4 increases efficiency of site-specific integration in Chinese hamster ovary cell line	5
A temperature-induced chitosanase bacterial cell-surface display system for the efficient production of chitooligosaccharides	5
Combining analytical approaches for better lignocellulosic biomass degradation: a way of improving fungal enzymatic cocktails?	5
Taguchi array optimization of the reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for sensitive and rapid detection of dengue virus serotype 2	5