Allergy

Papers
(The TQCC of Allergy is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Issue Information378
Issue Information326
Type 2 memory B cells: The repository of allergic memory?310
Issue Information191
Correspondence to “Basophil activation test as predictor of severity and threshold of allergic reactions to egg”190
Airway epithelial cell cilia transcriptomic dysregulation is associated with the inflammatory phenotype in asthma189
Ficolin‐A Protects Against Allergic Asthma via Suppressing ILC2‐Drived Type 2 Inflammation188
Dupilumab in Children Under 6 Years With Moderate‐to‐Severe Atopic Dermatitis: A 16‐Week Real‐World Prospective Study on Efficacy, Safety, and Local‐Systemic Immune Responses136
One‐strength dose escalation of house dust mite depot product for subcutaneous immunotherapy is safe and tolerable129
Clinical applicability of the urticaria control test in patients with chronic urticaria: Further evidence from 622 adult and pediatric patients with different disease subtypes119
Adherence to Mediterranean Diet During Pregnancy, Breastfeeding, and Development of Food Allergy in the Offspring: Results From the MEDALLION Cohort Study119
Atopic Dermatitis ( AD ) Related Cord Blood DNA Methylation Patterns Are Linked to Maternal 119
Impact of climate change on atopic dermatitis: A review by the International Eczema Council118
Transplacental Antimicrobial Antibodies and Childhood Asthma: Maternal Nativity as an Upstream Factor118
Next generation health guidelines: The role of real‐life data in evidence‐based medicine112
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25‐hydroxyvitamin D and risk of atopic diseases and infections in early childhood108
In Memory of Dr. Izabela Kuprys‐Lipinska: A Pioneering Clinician, Scientist, and Beloved Friend102
In memoriam: Lawrence M. Lichtenstein (1934–2022)101
Prospective (e‐diary) vs retrospective (ARIA) measures of severity in allergic rhinoconjunctivitis: An observational compatibility study101
Impact of COVID‐19 on care‐seeking patterns for hay fever in Japan: A retrospective claims database cohort study97
Correspondence to “Allergic bronchopulmonary aspergillosis with atopic, nonatopic, and sans asthma—Factor analysis”95
Cryopreservation Between Sample Processing and Analysis in Streamlined Basophil Activation Test92
Preclinical Development of GR2002, a Novel Anti‐TSLP Bispecific Antibody With Potent TSLP Inhibitory Effects92
TOP10SCAR : A Global Pharmacovigilance Study on Medications Most Frequently Related to Severe Cutaneous Adverse Rea91
Vaccine based on folded receptor binding domain‐PreS fusion protein with potential to induce sterilizing immunity to SARS‐CoV‐2 variants89
The second COVID‐19 mRNA vaccine dose enhances the capacity of Spike‐specific memory B cells to bind Omicron BA.288
IgG Removal Enhances the Sensitivity of Amoxicillin‐Specific IgE Detection in ImmunoCAP83
Algorithms in allergy: An algorithm for alpha‐Gal syndrome diagnosis and treatment, 2024 update82
Long‐term safety and efficacy of garadacimab for preventing hereditary angioedema attacks: Phase 3 open‐label extension study80
Longitudinal analyses of development of the immune system during the first five years of life in relation to lifestyle77
The Presence and Pathogenic Roles of M(IL‐33 + IL‐2) Macrophages in Allergic Airway Inflammation75
A Systematic Review and Meta‐Analysis on the Induction of Confirmed Eosinophilic Esophagitis as a Side Effect of Allergen Immunotherapy: An EAACI Tas74
Shotgun metagenomic sequencing on skin microbiome indicates dysbiosis exists prior to the onset of atopic dermatitis73
Immunoglobulin E response in health and disease beyond allergic disorders70
Hot topics in allergen immunotherapy, 2023: Current status and future perspective69
Oral and Gut Microbial Hubs Associated With Reaction Threshold Interact With Circulating Immune Factors in Peanut Allergy67
The Role of IgE in Crohn's Disease by Impairing the Capacity of Plasmacytoid Dendritic Cells to Generate FOXP3+ Tregs67
Pre‐existing inflammation reduces the response to contact allergens in Tmem79‐deficient mice66
An algorithm for the diagnosis and management of IgE‐mediated food allergy, 2024 update65
Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA60
Autoantibodies in COVID‐19 correlate with antiviral humoral responses and distinct immune signatures58
The impact of exposure to tobacco smoke and e‐cigarettes on asthma‐related outcomes: Systematic review informing the EAACI guidelines on environmental science for allergic diseases and asthma58
Angiomotin and angiostatin as asthma biomarkers: Implications for the regulation of airway remodeling and inflammation58
Core Outcome Set for IgE‐mediated food allergy clinical trials and observational studies of interventions: International Delphi consensus study ‘COMFA58
In vivo and ex vivo inflammatory responses of the esophageal mucosa to food challenge in adults with eosinophilic esophagitis58
Efficacy and safety of intranasal medications for allergic rhinitis: Network meta‐analysis57
Dupilumab improves health related quality of life: Results from the phase 3 SINUS studies57
Intranasal administration of a virus like particles‐based vaccine induces neutralizing antibodies against SARS‐CoV‐2 and variants of concern56
MUC1 deficiency induces the nasal epithelial barrier dysfunction via RBFOX3 shortage augment ubiquitin–proteasomal degradation in allergic rhinitis pathogenesis56
Issue Information55
Issue Information ‐ TOC55
Issue Information55
Oral abstracts (OAS)54
Reply to “Aspergillus fumigatus and personalized medicine: Toward a clinically reliable algorithm”52
Nutritional and environmental exposures in athletes: Implications on the epithelial barrier function52
Issue Information50
Sputum transcriptome analysis of co‐regulated genes related to arachidonic acid metabolism in N‐ERD50
Discrepancies in Beta‐Lactam Antibiotics Cross‐Reactivity: Implications for Clinical Practice49
Reply to correspondence: “The effectiveness of pollen allergen immunotherapy on allergic rhinitis over 18 years: A national cohort study in Denmark”49
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Epidemiological Study of Common Allergens Sensitizing Hay Fever Patients in Different Regions of Mainland China48
Childhood infections, asthma and allergy trajectories, and chronic rhinosinusitis in middle age: A prospective cohort study across six decades48
Childhood Asthma and Allergy Are Related to Accelerated Epigenetic Aging48
Anatomical Distribution and Quantification of IgE Secretion in Mouse Models of House Dust Mite Allergy47
The Molecular Allergology User's Guide version 2.0 is freely available!46
Type 2 IgG Memory B Cells as Precursors of IgE Plasma Cells46
Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps46
Genistein Reduced Eosinophilic Inflammation and Remodeling by Downregulating PAI‐1 and TSLP45
Forever Chemicals: An Exploratory, Population‐Based Analysis of Per‐ and Polyfluoroalkyl Substances Exposure and Effects on Sinonasal Health45
Evidence of epithelial remodelling but not epithelial–mesenchymal transition by transcriptome profiling in vernal keratoconjunctivitis44
Early expansion of allergen‐responsive LAP+ B regulatory cells in allergic rhinitis but not in allergic asthma subjects during allergen immunotherapy44
Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG143
Gastrointestinal Barrier Disruption in Post‐COVID Syndrome Fatigue Patients43
Immunotherapeutic effects of specific and nonspecific mRNA‐lipid nanoparticles in a mouse model of HDM‐induced airway inflammation43
Severe and refractory anaphylaxis in pediatric intensive care unit43
A Streamlined Miniaturized and Multi‐Allergen Basophil Activation Test Platform Amenable to Population‐Based Study42
Network analysis reveals age‐ and virus‐specific circuits in nasal epithelial cells of extremely premature infants42
Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice41
Tissue‐specific contribution of mucosal‐associated invariant T cells to allergic airway inflammation41
EAACI guidelines on environmental science in allergic diseases and asthma – Leveraging artificial intelligence and machine learning to develop a causality model in exposomics41
Natural course of pollen‐induced allergic rhinitis from childhood to adulthood: A 20‐year follow up41
Efficacy and safety of topical Streptococcus postbiotic emollient in adolescents and adults with mild‐to‐moderate atopic dermatitis: A randomized, double‐blind, vehicle‐controlled trial41
Differential presentation of hypersensitivity reactions to carboplatin and oxaliplatin: Phenotypes, endotypes, and management with desensitization40
CTP39 Compared With Reference Omalizumab in Chronic Spontaneous Urticaria: Results From a Double‐Blind, Randomized, Active‐Controlled, Phase 3 Study40
Non‐immediate hypersensitivity reactions to iomeprol: Diagnostic value of skin tests and cross‐reactivity with other iodinated contrast media40
TFEB signaling attenuates NLRP3‐driven inflammatory responses in severe asthma40
IL‐13: An essential cDC2s partner to maintain skin homeostasis39
Skin Lipid–Microbe Interplay Links Staphylococcus hominis to Barrier Control in Adult Atopic Dermatitis39
Issue Information39
Efficacy and Safety Profile of Animal Dander Immunotherapy: A Multicentre UK Study39
Vulnerability to Pollen‐Related Asthma Hospital Admissions in the UK Biobank: A Case‐Crossover Study39
Multi‐Omic Analysis of Scylla serrata Reveals the Allergen Landscape of Mud Crabs and Decapoda Species39
Glatiramer acetate induces mast cell degranulation via MRGPRX2, implications for local and systemic adverse reactions39
SARS‐CoV‐2 infection in severe asthma is associated with worsening of COVID‐19 through respiratory NLRP3 inflammasome activation38
Addressing the Growing Role of Junior Members in EAACI38
Molecular Signatures and Functional Pathways of Human Monocytes and Macrophages in Allergy: An EAACI AllergoOncology Scoping Review37
Age‐Related Increase in Anaphylaxis Severity Is Associated With Enhanced Sensitivity to Allergic Mediators37
Targeting interleukin‐5 with benralizumab: A novel treatment for drug rash with eosinophilia and systemic symptoms37
A vaccine targeting human IL‐4 and IL‐13 protects against asthma in humanized mice36
Optimal dose of adrenaline auto‐injector for children and young people at risk of anaphylaxis: A phase IV randomized controlled crossover study36
Development of the Cold Urticaria Activity Score36
Combining avidin with CD63 improves basophil activation test accuracy in classifying peanut allergy35
Legends of allergy and immunology: Otto Scheiner35
Cost‐effectiveness analysis of house dust mite allergen immunotherapy in children with allergic asthma35
Issue Information35
Quantitative analysis of urinary cytokines in food‐allergic and healthy individuals35
Intralymphatic Administration of Naked mRNA Induces Allergen‐Specific IgG , Promotes Th1 Responses35
Harnessing mass spectrometric methods for exquisite allergen product characterization35
Narrowband Ultraviolet B Induces Peripheral Regulatory T Cells to Exert Antigen‐Specific Immune Suppression35
Allergen‐Specific B Cell Responses Following Desensitisation and Natural Tolerance to Cow's Milk Allergy35
Prevalence of hypersensitivity reactions in various forms of mastocytosis: A pilot study of 2485 adult patients with mastocytosis collected in the ECNM registry34
Cashew oral immunotherapy for desensitizing cashew‐pistachio allergy (NUT CRACKER study)34
Effect of venom immunotherapy and sting challenge on health‐related quality of life measured by venom‐allergy quality of life questionnaire (VQLQ) in Jack jumper ant allergic patients34
Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions34
Indirect case‐matched comparison of anti‐IL4Rα versus anti‐IL5Rα on airway hyperresponsiveness34
Antibiotics for Acute Wheezing and Asthma Exacerbations: An EAACI Position Paper and Systematic Review34
Characteristics of Adolescents With Uncontrolled Severe Asthma Starting Dupilumab: The PEDIASTHMA Registry34
Impact of Residential Greeness Exposure on the Development of Allergic Diseases and Asthma and on Asthma Control—A Systematic Review for the EAACI Gu33
Serological testing for SARS‐CoV‐2 antibodies in clinical practice: A comparative diagnostic accuracy study33
Patient‐reported outcome measures in birch pollen allergic patients treated with sublingual immunotherapy reflect real life33
Salivary Metabolomic Signatures in Pediatric Eosinophilic Esophagitis33
Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial33
Incidence of healthcare utilization for allergic and respiratory infectious diseases in children with asthma before and during the COVID‐19 pandemic32
Exiting the Anthropocene: Achieving personal and planetary health in the 21st century32
Deciphering the Connection Between Atopic Dermatitis and Cardiovascular Diseases: Analysis of Clinical Associations and Cardiometabolic Proteins32
Food Allergy Genetics and Epigenetics: A Review of Genome‐Wide Association Studies32
SEB‐induced IL‐13 production in CLA+ memory T cells defines Th2 high and Th2 low responders in atopic dermatitis32
Anti‐KIT Barzolvolimab for Chronic Spontaneous Urticaria31
Impact of a drug allergy education course for non‐specialists: Findings from ADAPT—A randomized crossover trial31
Issue Information31
Oncostatin‐M Is Produced by Human Eosinophils and Expression Is Increased in Uncontrolled Severe Asthma31
Sex hormones and asthma: The role of estrogen in asthma development and severity31
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Issue Information30
Efficacy of eHealth monitoring in pediatric asthma30
Oral immunotherapy in alpha‐gal red meat allergy: Could specific IgE be a potential biomarker in monitoring management?30
The Uneven Risks of Childhood Asthma Under Extreme Temperatures and Its Interactions With Environmental Factors30
Author Index30
Safety of COVID‐19 vaccine challenge in patients with immediate adverse reactions to prior doses: A multi‐centre cohort study29
Gut microbiota and Lactobacillus species maintain the small intestine stem cell niche and ameliorate the severity of necrotizing enterocolitis29
Interferon‐γ‐inducible protein 10 augments atopic dermatitis via amplifying Th2 immune response29
Long‐term follow‐up of neutrophil activation after severe‐to‐critical SARS‐CoV‐2 infection: A longitudinal study28
Is there a direct link between skin barrier dysfunction and asthma?28
Legends of Allergy and Immunology: Gianni Marone28
Particulate Matter 2.5 Aggravates Airway Inflammation by Neutrophil‐Mediated Inflammasome Activation28
Mapping the way to strengthening epithelial barriers: Neuronal circuits in mucus regulation28
On a Rainy Day, Placebo Is the Ideal Treatment for Your Hay Fever28
Can polyamine metabolism in T helper cell lineage commitment be a new target in allergy research?27
Premastication—Review of an Infant Feeding Practice and Its Potential Impact on Allergy and Microbiome Development27
Thrombin cleaves IL‐33 and modulates IL‐33‐activated allergic lung inflammation27
Different mechanisms distinguishing childhood allergic diseases including allergic march27
Anaphylaxis Induced by Goat's and Sheep's Milk—A Rare Entity in Europe27
Secretion of Peanut Protein With IgE Crosslinking Capacity in Human Milk27
Asthma Remission in Adults: Role of Age at Asthma Onset, Smoking, Obesity, and Allergic Rhinitis26
Epidemiological variations in global burden of atopic dermatitis: An analysis of trends from 1990 to 201926
The impact of dupilumab treatment on SARS‐CoV‐2 T cell responses in atopic dermatitis patients26
Type 1/17 CD103+CD4+ nasal‐resident memory T cells in non‐eosinophilic chronic rhinosinusitis with nasal polyps26
Allergen‐specific B cell responses in oral immunotherapy‐induced desensitization, remission, and natural outgrowth in cow's milk allergy26
Two‐Year Data of Tapered Dupilumab Shows High Effectiveness in Chronic Rhinosinusitis with Nasal Polyps With Nonsteroidal Anti‐inflammatory Drug‐Exacerbated Respiratory Disease26
Pre‐Analytical Stability of Diagnostic Biomarkers in Primary Blood Tubes for Supporting Remote Allergy Care26
An Anti‐IL‐13 Vaccine Reduces Atopic Dermatitis in Humanized Mice and Induces Neutralizing Antibodies in Nonhuman Primates25
Distinct Tryptase Gene Copy Number Variations Correlate With Tryptase Levels in a Population‐Based Cohort25
The Bronchodilator and Anti‐Inflammatory Effect of Long‐Acting Muscarinic Antagonists in Asthma: An EAACI Position Paper25
Neonatal Bacillus Calmette‐Guérin Vaccination Decreases Eczema Incidence at 5 years: The MIS BAIR Randomised Controlled Trial25
Poultry exposure and environmental protection against asthma in rural children25
Effects of the immunoglobulin/histamine complex in chronic spontaneous urticaria focusing on remission induction25
IgE glycosylation is essential for the function of omalizumab25
A Novel Questionnaire and Algorithm for Work‐Related Asthma Screening and Surveillance: An EAACI Task Force Report25
Recombinant Hypoallergenic Cat Allergy Vaccines25
Fecal microbiota transplantation against moderate‐to‐severe atopic dermatitis: A randomized, double‐blind controlled explorer trial24
Effect‐modifying impact of age on sex‐based differences during oral immunotherapy24
IL‐13, periostin and dipeptidyl‐peptidase‐4 reveal endotype‐phenotype associations in atopic dermatitis24
Flow‐based basophil activation test in immediate drug hypersensitivity. An EAACI task force position paper24
The stimulation of TH2 cells results in increased IL‐5 and IL‐13 production via the H4 receptor24
CLA+ memory T cells in atopic dermatitis24
Dupilumab reduces symptom burden in allergic rhinitis and suppresses allergen‐specific IgE production24
Basal Serum Tryptase Outperforms Hereditary Alpha Tryptasemia as a Biomarker of Food Allergy Severity24
Predicting dupilumab treatment outcome in patients with primary diffuse type 2 chronic rhinosinusitis24
In this issue: Graphical abstract24
Suppressed IgG4 class switching in dupilumab‐ and TNF inhibitor‐treated patients after 24
Differentiation of bronchial epithelial spheroids in the presence of IL‐13 recapitulates characteristic features of asthmatic airway epithelia24
Issue Information23
Incidence of adverse events prompting switching between biologics among adults with asthma: A retrospective cohort study23
Obituary: Professor Marcus Maurer, Berlin, Germany23
Downregulation of Tight Junction Protein MAGI1 by Interferon‐γ Contributes to Barrier Dysfunction in Chronic Rhinosinusitis With Nasal Polyps23
Global burden of vaccine‐associated angioedema and their related vaccines, 1967–2023: Findings from the global pharmacovigilance database23
Issue Information23
Effect of indoor air pollution on atopic dermatitis in dogs23
An algorithm for the management of radiocontrast media hypersensitivity, 2024 update23
Gut Microbiota‐Derived Secondary Bile Acids Regulate Allergic Diseases23
The association between allergic rhinitis and the risk of coronavirus disease 2019 (COVID‐19): A national survey in China23
Correction to “Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge”23
Anaphylaxis Induced by Goat's and Sheep's Milk: An Allergen That We Should Keep Under Surveillance23
AI ‐Assisted Statistical Review: Could It Have Averted Retractions? A Case‐Based Perspective From Immunology23
Bulk T‐cell receptor sequencing confirms clonality in pediatric eosinophilic esophagitis and identifies a food‐specific repertoire23
Different inflammatory features of asthma according to gut microbiome enterotype22
Healthcare Professional Survey on Complementary Feeding and Allergy Prevention in High‐ Versus Low‐Risk Infants: An EAACI Task Force Report22
Eosinophilic allergic rhinitis is strongly associated with the CD45RBlo subset of CD161+ Th2 cells that secretes IL‐2, IL‐3, IL22
Reply to correspondence: Emollients in infancy to prevent atopic dermatitis: A systematic review and meta‐analysis22
Corrigendum to “Immune Regulation by Intralymphatic Immunotherapy With Modular Allergen Translocation MAT Vaccine”22
Reply to Correspondence: ‘Challenging the Frontier: Bridging Systemic Biomarkers and Small Airway Dynamics in Severe Asthma Management’22
Tissue levels of Alternaria allergen Alt a 1 reflect recurrence of refractory airway diseases22
Helminths' therapeutic potential to treat intestinal barrier dysfunction22
Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis22
Dietary fiber and fermented food consumption and its link to allergic responses22
Human Milk Microbiome Is Associated With Allergic Diseases in Early Childhood21
Tralokinumab therapy for moderate‐to‐severe atopic dermatitis: Clinical outcomes with targeted IL‐13 inhibition21
Lipidomic Analysis of Esophageal Epithelia Reveals a Distinctive Sphingolipid Profile in Eosinophilic Esophagitis21
How type‐2 dendritic cells induce Th2 differentiation: Instruction, repression, or fostering T cell‐T cell communication?21
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Allergen‐Specific IgE is a Stronger Predictor of Remission Following Peanut Oral Immunotherapy Than Age in Children Aged 1–10 Years21
Physical exercise, immune response, and susceptibility to infections—current knowledge and growing research areas21
Sesame eliciting and safe doses in a large sesame allergic population21
Allergen immunotherapy for asthma prevention: A systematic review and meta‐analysis of randomized and non‐randomized controlled studies21
Systematic review of the association between short‐chain fatty acids and allergic diseases21
Dupilumab and Blood Eosinophilia: A Disease‐Specific Phenomenon?21
Long‐term changes in milk component immunoglobulins reflect milk oral immunotherapy outcomes in Finnish children21
Infantile colic is associated with development of later constipation and atopic disorders21
Allergenic potency of various foods of mammalian origin in patients with α‐Gal syndrome21
Spatial transcriptomics combined with single‐cell RNA‐sequencing unravels the complex inflammatory cell network in atopic dermatitis21
Patient‐centered dupilumab dosing regimen leads to successful dose reduction in persistently controlled atopic dermatitis21
Issue Information ‐ TOC20
Issue Information ‐ TOC20
Efficacy of Omalizumab, Dupilumab, and Remibrutinib in Chronic Spontaneous Urticaria: Phase Data and Placebo Response20
Patients With Atopic Dermatitis Show Increased Clonal Hematopoiesis and Risk of Hematological Cancer20
Exhaled Nitric Oxide and Sputum Eosinophils Are Complementary Tools for Diagnosing Occupational Asthma20
Corrigendum: Role of yes‐associated protein in interleukin‐13 induced nasal remodeling of chronic rhinosinusitis with nasal polyps20
Issue information ‐ Cover and Editorial Board20
Issue Information20
Anaphylaxis and desensitization differently activate and induce IL‐8 release by mast cells in a human peanut allergy in vitro model20
Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic Airway Inflammation20
Issue Information20
Legends of allergy and immunology: Alberto Mantovani, a visionary scientist unraveling the complexity of innate immunity in cancer and inflammation20
Graphical abstracts and highlights20
Algorithm for the Management of Primary Diffuse Chronic Rhinosinusitis20
Occupational Mite Allergy and Asthma: An EAACI Task Force Report20
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Induction of immunosuppressive CD39 but not the trafficking C‐C chemokine receptor 4 on Treg during LAR in mite allergic asthma19
Trait profiles in difficult‐to‐treat asthma: Clinical impact and response to systematic assessment19
Fungal exposome, human health, and unmet needs: A 2022 update with special focus on allergy19
Asthma endotypes in elite athletes: A cross‐sectional study of European athletes participating in the Olympic Games19
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Migration and allergic diseases: Findings from a population‐based study in adults in Amsterdam, the Netherlands19
The SCF/KIT axis in human mast cells: Capicua acts as potent KIT repressor and ERK predominates PI3K19
The developing immune system in preterm born infants: From contributor to potential solution for respiratory tract infections and wheezing19
CMTM4 as a new partner for IL‐17 receptor: Adding a piece in the puzzle of IL17‐driven diseases19
Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction19
Molecular reactivity profiling upon immunotherapy with a 300 IR sublingual house dust mite tablet reveals marked humoral changes towards major allergens19
Delta or Omicron BA.1/2‐neutralizing antibody levels and T‐cell reactivity after triple‐vaccination or infection19
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