OOIR: Observatory of International Research

Papers

(The TQCC of Immunological Reviews is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Issue Information	309
Cover Image	260
The Structural Biology of T‐Cell Antigen Detection at Close Contacts	251
Cytotoxicity as a form of immunogenic cell death leading to efficient tumor antigen cross‐priming	138
Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance	129
Human autoantibodies neutralizing type I IFNs: From 1981 to 2023	125
Bridging pDCs and cDCs : The Identity of Transitional Dendritic Cells	124
NETosis: Sculpting tumor metastasis and immunotherapy	121
Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases	110
Antigen‐specific and cross‐reactive T cells in protection and disease	109
The Thymus Regeneration Paradox: The Search for Stemness in an Involuting Organ	107
In Defense of Homeostasis: Innate Immunity in Cardiac Injury and Repair	94
Reframing Thymic Biology: From AIRE to Mimetics, Thymflammation, Regeneration, and Beyond	92
Immune checkpoint inhibitors in infectious disease	83
Superoxide: The enigmatic chemical chameleon in neutrophil biology	82
IgE‐Mediated Activation of Mast Cells and Basophils in Health and Disease	78
Role of inflammasomes and neuroinflammation in epilepsy	76
Metabolic regulation of type I interferon production	74
Issue Information	73
Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy	69
The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity	69
Layered origins of lymphoid tissue inducer cells	67
B‐1 lymphocytes in adipose tissue as innate modulators of inflammation linked to cardiometabolic disease	64
Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation	60
Inflammasome‐mediated pyroptosis in defense against pathogenic bacteria	59

Mechanisms Promoting Stability of B Cells	59
The immune system in Down Syndrome: Autoimmunity and severe infections	58
The importance of IgG glycosylation—What did we learn after analyzing over 100,000 individuals	57
Inflammasome Activation by RNA Respiratory Viruses: Mechanisms, Viral Manipulation, and Therapeutic Insights	56
Allosteric Changes Underlie the Outside‐In Transmission of Activatory Signals in the TCR	56
Maternal influences on offspring food allergy	55
Cover Image	55
With complements: C3 inhibition in the clinic	55
Functional Insights From Immunoreceptor Structures	54
Issue Information	54
An introduction to neuroimmunology	54
Common variable immunodeficiency, cross currents, and prevailing winds	53
T1‐T2 Interplay in the Complex Immune Landscape of Severe Asthma	52
	49
Issue Information	48
	48
Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation	48
Artery Tertiary Lymphoid Organs Form Neuroimmune Cardiovascular Interfaces in Atherosclerosis	47
Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy	46
Immune Mechanisms of Viral, Autoimmune, and Immune Checkpoint Inhibitor‐Associated Myocarditis	46
Cortical Thymic Epithelial Cells: Key Developers of the Code of T‐Cell Selection and TCR Repertoire Diversity	46
Dendritic Cell Organization and Function in Innate and Adaptive Immune Defense Within Lymph Nodes	45
Autoimmunity and the microbiome	45
Sex Differences in Lung Immunity	45
Sex Differences in Asthma Pathogenesis	45
Issue Information	44
Deconstructing the Thymic Microenvironment Through Genesis to Senescence	43
Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions	43
Correction to “The Journey Toward Disease Modification in Cow Milk Protein Allergy”	43
Gene regulation in inborn errors of immunity: Implications for gene therapy design and efficacy	43
Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity	42
Glycobiology of IgE	42
MAP Kinase Signaling at the Crossroads of Inflammasome Activation	41
Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement	41
Human neutrophils ≠ murine neutrophils: Does it matter?	41
PANoptosis: Mechanisms, biology, and role in disease	41
JAK/STAT defects and immune dysregulation, and guiding therapeutic choices	41
Axes of heterogeneity in human tissue‐resident memory T cells	40
	40
Modulation of immunity by the secreted phospholipase A₂ family	40
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond	39
Cover Image	39
Factor D	38
Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis	38
Integrative Roles of Pro‐Inflammatory Cytokines on Airway Smooth Muscle Structure and Function in Asthma	37
From Lymphotoxin to Tertiary Lymphoid Structures and Beyond	36
Rethinking Immunity in Tissues: The Biology of Tertiary Lymphoid Structures	36
Structural Immunology of SARS‐CoV‐2	36
	36
Ketone body metabolism and the NLRP3 inflammasome in Alzheimer's disease	36

	35
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design	33
Cell type‐specific molecular mechanisms and implications of necroptosis in inflammatory respiratory diseases	33
Host immune responses in the central nervous system during fungal infections	33
Irritable bowel syndrome: When food is a pain in the gut	32
Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A	32
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi‐protein cascade of the complement system	32
Development and organization of omental milky spots	31
Gut microbiota as a sensor of autoimmune response and treatment for rheumatoid arthritis	31
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome	30
Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic health	30
Issue Information	29
Cover Image	29
Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease	29
Cover Image	29
Low‐molecular weight inhibitors of the alternative complement pathway	28
Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?	28
Biology of IgE	28
Tissue immunity to SARS‐CoV‐2: Role in protection and immunopathology*	28
Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong?	28
Hemophagocytic lymphohistiocytosis: A disorder of T cell activation, immune regulation, and distinctive immunopathology	27
Innate Immunity and Asthma Exacerbations: Insights From Human Models	27
Type 2 IgG Memory B Cells and Long‐Lived IgE Plasma Cells in the Persistence of Allergy	27
No time to die: Epigenetic regulation of natural killer cell survival	27
Immunogenicity and efficacy of Ad26.COV2.S: An adenoviral vector–based COVID‐19 vaccine	26
Human Atypical B Cells. An Overview	26
Neutrophils in aging and aging‐related pathologies	26
Metabolic Stress and Immune Activation in Heart Failure With a Preserved Ejection Fraction	26
Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment	26
Issue Information	25
Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity	25
Issue Information	25
	25
Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events	25
Swimming Through Dendritic Cell Biology: Insights From Fish Models	24
The impact of the human gut microbiome on the treatment of autoimmune disease	24
Contributions of animal models to mechanistic understandings of antibody‐dependent disease and roles of the amplification loop	24
The nervous system during COVID‐19: Caught in the crossfire	24
ILC2 Diversity, Location, and Function in Pulmonary Disease	24
Understanding the diversity and dynamics of in vivo efferocytosis: Insights from the fly embryo	23
	23
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation	23
Issue Information	23
The impact of neuroinflammation on neuronal integrity	23
The evolving landscape of immune‐related adverse events that follow immune checkpoint immunotherapy in cancer patients	23
Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response	23
	23
Thymflammation: The Role of a Constitutively Active Inflammatory Network and “Ectopic” Cell Types in the Thymus in the Induction of T Cell Tolerance and Beyond	23
Innate Immune Sensors in Health and Disease	22
G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions	22
A comprehensive review of sensors of radiation‐induced damage, radiation‐induced proximal events, and cell death	22
Signals that control MAIT cell function in healthy and inflamed human tissues	22
Inflammation‐Driven Lymphoid Structures: Organization, Function, and Clinical Impact Across Autoimmunity, Cancer, and Checkpoint Toxicity	22
Established and emerging roles for mitochondria in neutrophils	22
Microbes and the fate of neutrophils	22
Dendritic Cell Heterogeneity Tailored to Their Function	22