OOIR: Observatory of International Research

Papers

(The TQCC of Immunological Reviews is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)

Article	Citations
Issue Information	268
The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity	137
B‐1 lymphocytes in adipose tissue as innate modulators of inflammation linked to cardiometabolic disease	130
Layered origins of lymphoid tissue inducer cells	130
Mechanisms Promoting Stability of B Cells	129
Allosteric Changes Underlie the Outside‐In Transmission of Activatory Signals in the TCR	117
Inflammasome Activation by RNA Respiratory Viruses: Mechanisms, Viral Manipulation, and Therapeutic Insights	117
Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy	114
Inflammasome‐mediated pyroptosis in defense against pathogenic bacteria	97
The importance of IgG glycosylation—What did we learn after analyzing over 100,000 individuals	96
The immune system in Down Syndrome: Autoimmunity and severe infections	92
With complements: C3 inhibition in the clinic	84
Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation	83
Cover Image	80
Issue Information	77
Functional Insights From Immunoreceptor Structures	76
	73
	68
Issue Information	67
Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation	61
Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy	61
Sex Differences in Asthma Pathogenesis	60
Cortical Thymic Epithelial Cells: Key Developers of the Code of T‐Cell Selection and TCR Repertoire Diversity	60
Sex Differences in Lung Immunity	60
Common variable immunodeficiency, cross currents, and prevailing winds	58

Autoimmunity and the microbiome	57
Maternal influences on offspring food allergy	57
Immune Mechanisms of Viral, Autoimmune, and Immune Checkpoint Inhibitor‐Associated Myocarditis	56
Dendritic Cell Organization and Function in Innate and Adaptive Immune Defense Within Lymph Nodes	56
Artery Tertiary Lymphoid Organs Form Neuroimmune Cardiovascular Interfaces in Atherosclerosis	56
An introduction to neuroimmunology	55
T1‐T2 Interplay in the Complex Immune Landscape of Severe Asthma	51
Correction to “The Journey Toward Disease Modification in Cow Milk Protein Allergy”	50
Issue Information	50
Gene regulation in inborn errors of immunity: Implications for gene therapy design and efficacy	50
Glycobiology of IgE	49
JAK/STAT defects and immune dysregulation, and guiding therapeutic choices	49
Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity	48
Axes of heterogeneity in human tissue‐resident memory T cells	48
Human neutrophils ≠ murine neutrophils: Does it matter?	48
Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions	48
MAP Kinase Signaling at the Crossroads of Inflammasome Activation	47
Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement	47
Modulation of immunity by the secreted phospholipase A₂ family	47
Deconstructing the Thymic Microenvironment Through Genesis to Senescence	47
	46
PANoptosis: Mechanisms, biology, and role in disease	46
Rethinking Immunity in Tissues: The Biology of Tertiary Lymphoid Structures	46
Cover Image	46
	46
Ketone body metabolism and the NLRP3 inflammasome in Alzheimer's disease	45
Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis	45
Factor D	44
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond	43
From Lymphotoxin to Tertiary Lymphoid Structures and Beyond	43
Integrative Roles of Pro‐Inflammatory Cytokines on Airway Smooth Muscle Structure and Function in Asthma	42
Structural Immunology of SARS‐CoV‐2	42
	41
Cell type‐specific molecular mechanisms and implications of necroptosis in inflammatory respiratory diseases	40
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design	39
Gut microbiota as a sensor of autoimmune response and treatment for rheumatoid arthritis	38
Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic health	38
Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A	38
Development and organization of omental milky spots	36
Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease	35
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi‐protein cascade of the complement system	34
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome	33
Cover Image	32
Irritable bowel syndrome: When food is a pain in the gut	32
Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?	31
Cover Image	31
Innate Immunity and Asthma Exacerbations: Insights From Human Models	30
Type 2 IgG Memory B Cells and Long‐Lived IgE Plasma Cells in the Persistence of Allergy	30
Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong?	30
Biology of IgE	30

Metabolic Stress and Immune Activation in Heart Failure With a Preserved Ejection Fraction	30
Low‐molecular weight inhibitors of the alternative complement pathway	29
Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment	29
No time to die: Epigenetic regulation of natural killer cell survival	29
Issue Information	28
Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events	28
Neutrophils in aging and aging‐related pathologies	28
Human Atypical B Cells. An Overview	28
Hemophagocytic lymphohistiocytosis: A disorder of T cell activation, immune regulation, and distinctive immunopathology	28
Issue Information	27
Contributions of animal models to mechanistic understandings of antibody‐dependent disease and roles of the amplification loop	27
	27
Swimming Through Dendritic Cell Biology: Insights From Fish Models	27
Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity	26
The impact of neuroinflammation on neuronal integrity	26
The impact of the human gut microbiome on the treatment of autoimmune disease	26
ILC2 Diversity, Location, and Function in Pulmonary Disease	26
	25
The evolving landscape of immune‐related adverse events that follow immune checkpoint immunotherapy in cancer patients	25
Issue Information	25
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation	25
	25
Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response	25
Thymflammation: The Role of a Constitutively Active Inflammatory Network and “Ectopic” Cell Types in the Thymus in the Induction of T Cell Tolerance and Beyond	25
G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions	24
Dendritic Cell Heterogeneity Tailored to Their Function	24
Established and emerging roles for mitochondria in neutrophils	24
Microbes and the fate of neutrophils	24
Gastrointestinal mucosal toxicities from immune checkpoint inhibitors: Current understanding and future directions	24
Thymic Dendritic Cells Revisited	24
Signals that control MAIT cell function in healthy and inflamed human tissues	24
Inflammation‐Driven Lymphoid Structures: Organization, Function, and Clinical Impact Across Autoimmunity, Cancer, and Checkpoint Toxicity	24
	23
A comprehensive review of sensors of radiation‐induced damage, radiation‐induced proximal events, and cell death	23
Life‐threatening antibodies: The discovery of anaphylaxis	23
Understanding the diversity and dynamics of in vivo efferocytosis: Insights from the fly embryo	23
	23
Innate Immune Sensors in Health and Disease	23