OOIR: Observatory of International Research

Papers

(The TQCC of Immunological Reviews is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Issue Information	270
Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases	235
Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance	134
Imaging dendritic cell functions*	96
Cytotoxicity as a form of immunogenic cell death leading to efficient tumor antigen cross‐priming	88
Cover Image	85
The Structural Biology of T‐Cell Antigen Detection at Close Contacts	83
Superoxide: The enigmatic chemical chameleon in neutrophil biology	79
Immune checkpoint inhibitors in infectious disease	78
Role of inflammasomes and neuroinflammation in epilepsy	74
Metabolic regulation of type I interferon production	72
Human autoantibodies neutralizing type I IFNs: From 1981 to 2023	67
NETosis: Sculpting tumor metastasis and immunotherapy	66
IgE‐Mediated Activation of Mast Cells and Basophils in Health and Disease	65
Issue Information	63
Antigen‐specific and cross‐reactive T cells in protection and disease	63
Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy	61
B‐1 lymphocytes in adipose tissue as innate modulators of inflammation linked to cardiometabolic disease	61
Layered origins of lymphoid tissue inducer cells	59
The immune system in Down Syndrome: Autoimmunity and severe infections	57
The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity	55
Inflammasome Activation by RNA Respiratory Viruses: Mechanisms, Viral Manipulation, and Therapeutic Insights	55
Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation	55
Inflammasome‐mediated pyroptosis in defense against pathogenic bacteria	51
Thymic and extrathymic Aire‐expressing cells in maternal‐fetal tolerance*	48

The importance of IgG glycosylation—What did we learn after analyzing over 100,000 individuals	48
With complements: C3 inhibition in the clinic	44
Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation	44
Allosteric Changes Underlie the Outside‐In Transmission of Activatory Signals in the TCR	44
Cortical Thymic Epithelial Cells: Key Developers of the Code of T‐Cell Selection and TCR Repertoire Diversity	43
Cover Image	42
Functional Insights From Immunoreceptor Structures	42
Maternal influences on offspring food allergy	41
Autoimmunity and the microbiome	41
An introduction to neuroimmunology	40
	38
Issue Information	38
Understanding immunity in a tissue‐centric context: Combining novel imaging methods and mathematics to extract new insights into function and dysfunction*	38
Issue Information	38
Diving into the mechanism of action of tumor immunotherapies with intravital imaging*	38
Common variable immunodeficiency, cross currents, and prevailing winds	38
Activation pathways that drive CD4⁺ T cells to break tolerance in autoimmune diseases*	37
ZAP70, too little, too much can lead to autoimmunity*	37
T1‐T2 Interplay in the Complex Immune Landscape of Severe Asthma	36
Deconstructing the Thymic Microenvironment Through Genesis to Senescence	36
Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy	36
Issue Information	36
	36
Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions	36
Correction to “The Journey Toward Disease Modification in Cow Milk Protein Allergy”	35
Axes of heterogeneity in human tissue‐resident memory T cells	35
Fetal inflammatory response at the fetomaternal interface: A requirement for labor at term and preterm*	34
Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity	34
Glycobiology of IgE	34
Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement	34
Gene regulation in inborn errors of immunity: Implications for gene therapy design and efficacy	34
JAK/STAT defects and immune dysregulation, and guiding therapeutic choices	33
Modulation of immunity by the secreted phospholipase A₂ family	33
MAP Kinase Signaling at the Crossroads of Inflammasome Activation	32
Human neutrophils ≠ murine neutrophils: Does it matter?	32
PANoptosis: Mechanisms, biology, and role in disease	31
	30
Integrative Roles of Pro‐Inflammatory Cytokines on Airway Smooth Muscle Structure and Function in Asthma	30
Ketone body metabolism and the NLRP3 inflammasome in Alzheimer's disease	29
Structural Immunology of SARS‐CoV‐2	29
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond	29
Factor D	29
From Lymphotoxin to Tertiary Lymphoid Structures and Beyond	29
Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic neuroinflammation	29
Cover Image	29
Mechanisms of immune regulation by the placenta: Role of type I interferon and interferon‐stimulated genes signaling during pregnancy*	29
Irritable bowel syndrome: When food is a pain in the gut	29
Cell type‐specific molecular mechanisms and implications of necroptosis in inflammatory respiratory diseases	28
Host immune responses in the central nervous system during fungal infections	28
	27

Development and organization of omental milky spots	27
Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic health	27
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi‐protein cascade of the complement system	27
Gut microbiota as a sensor of autoimmune response and treatment for rheumatoid arthritis	27
Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A	27
Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease	26
Many Achilles’ heels of B and T cell tolerance	26
Issue Information	26
Immunogenicity and efficacy of Ad26.COV2.S: An adenoviral vector–based COVID‐19 vaccine	25
Cover Image	25
No time to die: Epigenetic regulation of natural killer cell survival	25
Tissue immunity to SARS‐CoV‐2: Role in protection and immunopathology*	25
Cover Image	25
Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment	24
Human Atypical B Cells. An Overview	24
Transcriptional and epigenetic regulation in thymic epithelial cells*	24
Low‐molecular weight inhibitors of the alternative complement pathway	24
Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong?	23
Stability and change in epigenetic regulation of immune cells	23
Hemophagocytic lymphohistiocytosis: A disorder of T cell activation, immune regulation, and distinctive immunopathology	22
Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events	22
Innate Immunity and Asthma Exacerbations: Insights From Human Models	22
Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?	22
Neutrophils in aging and aging‐related pathologies	22
Issue Information	21
Contributions of animal models to mechanistic understandings of antibody‐dependent disease and roles of the amplification loop	20
	20
The impact of the human gut microbiome on the treatment of autoimmune disease	20
Visualization and functional characterization of lymphoid organ fibroblasts*	20
Issue Information	20
ILC2 Diversity, Location, and Function in Pulmonary Disease	20
The nervous system during COVID‐19: Caught in the crossfire	20
	19
The evolving landscape of immune‐related adverse events that follow immune checkpoint immunotherapy in cancer patients	19
The impact of neuroinflammation on neuronal integrity	19
Gastrointestinal mucosal toxicities from immune checkpoint inhibitors: Current understanding and future directions	19
Epigenetic regulation of inflammation by CxxC domain‐containing proteins*	19
	19
Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response	18
Understanding the diversity and dynamics of in vivo efferocytosis: Insights from the fly embryo	18
Real‐time imaging of inflammation and its resolution: It’s apparent because it’s transparent*	18
Innate Immune Sensors in Health and Disease	18
Thymflammation: The Role of a Constitutively Active Inflammatory Network and “Ectopic” Cell Types in the Thymus in the Induction of T Cell Tolerance and Beyond	18
Imaging leukocyte migration through afferent lymphatics*	18
Signals that control MAIT cell function in healthy and inflamed human tissues	17
A comprehensive review of sensors of radiation‐induced damage, radiation‐induced proximal events, and cell death	17
Established and emerging roles for mitochondria in neutrophils	17
Issue Information	17
Microbes and the fate of neutrophils	17
G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions	17
	17
	16
Correction to “The anti‐inflammatory and antiviral properties of anionic pulmonary surfactant phospholipids”	16
Additional Cover	16
Chemo‐ and mechanosensing by dendritic cells facilitate antigen surveillance in the spleen*	16
Life‐threatening antibodies: The discovery of anaphylaxis	16
Exploring the roles of prostanoids, leukotriens, and dietary fatty acids in cutaneous inflammatory diseases: Insights from pharmacological and genetic approaches	16
Role of B cells in immune‐related adverse events following checkpoint blockade	16
Regulation of immune responses to food by commensal microbes	16
IgE versus IgG and IgA: Differential roles of allergen‐specific antibodies in sensitization, tolerization, and treatment of allergies	16