OOIR: Observatory of International Research

Papers

(The TQCC of Brazilian Journal of Medical and Biological Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Cognitive behavioral stress management effectively facilitates neurologic recovery, alleviates mental distress, and elevates health status in acute ischemic stroke patients	65
Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria	25
Early introduction of exercise prevents insulin resistance in postnatal overfed rats	24
Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone	24
Bidirectional genetic selection of behaviors involved in social interaction of Wistar rats	21
Eight-year change in carotid intima-media thickness and associated risk factors in adults with and without psoriasis - the ELSA-Brasil cohort study	17
Telomerase inhibitors TMPyP4 and thymoquinone decreased cell proliferation and induced cell death in the non-small cell lung cancer cell line LC-HK2, modifying the pattern of focal adhesion	16
Volumetric analysis of the damage and response of non-invasive brain stimulation in patients with spatial neglect after stroke: a subgroup analysis of the ELETRON trial	16
Low-intensity pulsed ultrasound inhibits chondrocyte senescence by inhibiting PI3K/AKT/mTOR signaling	15
ACE gene polymorphisms (rs4340) II and DI are more responsive to the ergogenic effect of caffeine than DD on aerobic power, heart rate, and perceived exertion in a homogeneous Brazilian group of adole	14
Erratum notice for: “Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria” [Braz J Med Biol Res 2023: 56, e12894]	13
Nanosized copper particles induced mesangial cell toxicity via the autophagy pathway	13
The dynamic changes in quantitative parameters of diffusion-weighted imaging at different b-values in a prostate cancer mouse model and their correlation with histopathology parameters	13
Anti-inflammatory, procollagen, and wound repair properties of topical insulin gel	12
The duration-dependent and sex-specific effects of neonatal sevoflurane exposure on cognitive function in rats	12
Resveratrol as a cardioprotective adjuvant for 5-fluorouracil in the treatment of gastric cancer cells	11
Prediction of early myocardial damage in obstructive sleep apnea patients using combined logistic regression and QUEST decision tree models	11
Ovarian hormones influence immune response to liver ischemia-reperfusion	11
GSK3B inhibition reduced cervical cancer cell proliferation and migration by modulating the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition	11
Erratum notice for: “Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways” [Braz J Med Biol Res 2020;53(2): e8793]	11
Reference equations of oxygen uptake for the step test in the obese population	10
Effects of N-butanol extract of Amygdalus mongolica on rats with bleomycin‐induced pulmonary fibrosis based on metabolomics	10
Evaluation of cytokine levels in HIV-infected individuals on therapy with tenofovir, lamivudine, and dolutegravir	10
Barriers to patient recruitment in a poststroke neurorehabilitation multicenter trial in Brazil	10
The role and mechanisms of cordycepin in inhibiting cancer cells	9

Is near-infrared spectroscopy a promising predictor for early intracranial hemorrhage diagnosis in the Emergency Department?	9
Factors affecting executive function performance of Brazilian elderly in the Stroop test	9
Didymin protects against polystyrene nanoplastic-induced hepatic damage in male albino rats by modulation of Nrf-2/Keap-1 pathway	9
Validation of the online PREDICT tool in a cohort of early breast cancer in Brazil	8
Neurocognitive effects of proanthocyanidin in Alzheimer's disease: a systematic review of preclinical evidence	8
Nutrition management by a multidisciplinary team for prevention of nutritional deficits and morbidity following esophagectomy	8
Prevalence and risk factors for falls among older Chinese adults in the community: findings from the CLHLS study	8
In vitro effects of lapachol and β-lapachone against Leishmania amazonensis	8
Effects of imposed and self-selected exercise on perceptual and affective responses, muscle function, quality, and functionality of strength training in older women and men: a randomized trial	8
Eugenol inhibits preadipocyte differentiation and lipid accumulation via upregulating ATF3	8
Fatty acid profile and effect of Plukenetia volubilis L. (sacha inchi) oil on lipid metabolism in rats fed a high-fat diet	8
Correlation of common inflammatory cytokines with cognition impairment, anxiety, and depression in acute ischemic stroke patients	8
Mental stress induces endothelial dysfunction by AT1R-mediated redox imbalance in overweight/obese men	8
Quantifying lactulose and mannitol using LC-MS/MS in a clinical study of children with environmental enteric disease	8
Epidemiological and clinical factors of breast cancer in a population of mostly Afro-descendant women	8
ITGBL1 transcriptionally inhibited by JDP2 promotes the development of pancreatic cancer through the TGF-beta/Smad pathway	7
Assessing the reaction to and efficacy of the Screener drug discovery and development board game as a pedagogical tool in postgraduate courses	7
The essential role of adenine nucleotide translocase 4 on male reproductive function in mice	7
Sulfasalazine prevents lung injury due to intra-abdominal sepsis in rats: possible role of Nrf2 and angiopoietin-2	7
Puerarin protects the fatty liver from ischemia-reperfusion injury by regulating the PI3K/AKT signaling pathway	7
CAR-T therapy for gastrointestinal cancers: current status, challenges, and future directions	7
A U-shaped relationship between sleep duration and tinnitus incidence: analysis of 13,871 participants from NHANES	7
Machine learning approaches and genetic determinants that influence the development of type 2 diabetes mellitus: a genetic association study in Brazilian patients	7
Self-reported carbohydrate supercompensation and supplementation strategies adopted by Olympic triathlon athletes	6
Data-driven decision making for the screening of cognitive impairment in primary care: a machine learning approach using data from the ELSA-Brasil study	6
Unveiling immune mechanisms and potential biomarkers in intervertebral disc degeneration through integrated analysis	6
Giant uterine tumor and miscarriage: how to proceed?	6
Diagnostic value of serum inflammatory markers in predicting early refractoriness of transarterial chemoembolization in patients with Barcelona Clinic Liver Cancer Stage 0, A, and B hepatocellular car	6
Genetic polymorphisms and protein levels in vocal fold leukoplakia: a systematic review	6
Effect of different pacing strategies on 4-km cycling time trial performance	6
Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor	6
Effects of endurance exercise training on endoplasmic reticulum stress in pancreatic islets of obese mice	6
Trifolirhizin improves the hyperproliferation and excessive inflammatory response in human HaCaT keratinocytes and ameliorates skin lesions in psoriasis-like mouse models	6
Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells	6
Integrative analyses of genetic characteristics associated with skeletal endothelial cells	6
Effects of an early rehabilitation program for adult cystic fibrosis patients during hospitalization: a randomized clinical trial	6
The body weight-walking distance product as a superior parameter in determining the VO2 on-kinetics in coronary artery disease	6
Effect of high-intensity childhood games on heart rate variability, saliva leptin concentrations, and body composition in children	6
H2S inhibits high glucose-induced osteoblast injury by inhibiting ferroptosis in diabetic osteoporosis in vitro	6
Extraction and characterization of collagen from the skin of Amazonian freshwater fish pirarucu	6
Angiotensin receptor-neprilysin inhibitors and cardiac remodeling	6
Deoxycholic acid aggravates necrotizing enterocolitis through downregulation of mesenchymal-epithelial transition factor expression	6
Synergy between isobavachalcone and doxorubicin suppressed the progression of anaplastic thyroid cancer through ferroptosis activation	6
Quality of life and functional capacity in depressive patients on hemodialysis: a systematic review and meta-analysis	6
Luteolin ameliorates loperamide-induced functional constipation in mice	5
Effect of COVID-19 on cardiorenal axis: known or unknown universe?	5
Kidney health for all: bridging the gap in kidney health education and literacy	5
Systemic effects of oral tolerance improve the healing of several and concomitant wounds on different parts of the body	5
An overview on the current available treatment for COVID-19 and the impact of antibiotic administration during the pandemic	5
Saccharomyces boulardii supplementation does not affect anaerobic power gain induced by short-term sprint interval training in physically active individuals	5

Cortical thickness is related to working memory performance after non-invasive brain stimulation	5
The LDL/HDL ratio predicts long-term risk of coronary revascularization in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: a cohort study	5
FNDC5/Irisin in dementia and cognitive impairment: update and novel perspective	5
Bioinformatic features and immunological response of recombinant antigen CTLA4-IgV-EgG1Y162 against Echinococcus granulosus	5
Upregulation of PGC-1α expression by pioglitazone mediates prevention of sepsis-induced acute lung injury	5
Study of the relationship between regional cerebral saturation and pCO2 changes during mechanical ventilation to evaluate modifications in cerebral perfusion in a newborn piglet model	5
N-glycosylation of ACTRIIB enhances protein stability leading to rapid cell proliferation and strong resistance to docetaxel in nasopharyngeal carcinoma	5
Salvia miltiorrhiza: insights on the protective effect and mechanism of myocardial ischemia-reperfusion injury	5
Investigations on the cytotoxicity and antimicrobial activities of terezine E and 14-hydroxyterezine D	5
Loneliness, spiritual well-being, and death perception, as well as their risk factors in urological cancer patients	5
Evaluation of oxidative stress markers in ethanol users	4
Biochanin A exerts an anti-inflammatory effect on adipose tissue and liver of ovariectomized obese mice	4
Assessing multiple factors affecting the gut microbiome structure of very preterm infants	4
A short review on the features of the non-obese diabetic Goto-Kakizaki rat intestine	4
A model for preservation of thymocyte-depleted thymus	4
Moderate physical exercise and ATP modulate the P2X7 receptor and improve cisplatin-induced gastric emptying delay in rats	4
Role of cyclooxygenases 1 and 2 in the maintenance of colonic mucosal integrity in an experimental colitis model	4
Efficacy of convalescent plasma in hospitalized COVID-19 patients: findings from a controlled trial	4
Aerobic capacity evaluation of Sprague Dawley rats in treadmill running: comparison between protocols	4
Factors associated with non-treatment of hypertension and gender differences at baseline in the ELSA-Brasil cohort	4
Serum levels of IL-12, IL-18, and IL-21 are indicators of viral load in patients chronically infected with HBV	4
Genomic instability in long-term culture of human adipose-derived mesenchymal stromal cells	4
Foxa1 mediates eccrine sweat gland development through transcriptional regulation of Na-K-ATPase expression	4
The role of the PKCζ/JNK signaling pathway in regulating the development of femoral head necrosis	4
Chrysin induces cell death and inhibits migration and invasion in squamous cervical carcinoma using a three-dimensional cell culture model	4
Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line	4
Effects of traction therapy on atlantoaxial joint dislocation-induced cervical vertigo	4
Minimally invasive autopsy as a useful tool for RNA extraction in molecular pathology of lung diseases	4
Toxic effects of Arianor Ebony hair dye on human cells	4
Predictive value of DNA repair gene expression for response to neoadjuvant chemotherapy in breast cancer	4
Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro	4
Acupuncture for generalized anxiety disorder: a study protocol for a randomized controlled trial	4
Impact of targeted nursing care and nutritional support on clinical outcomes in diabetic nephropathy patients undergoing maintenance hemodialysis	4
Association among cardiopulmonary and metabolic rehabilitation, arrhythmias, and myocardial ischemia responses of patients with HFpEF or HFmrEF	4
ZC3H12D upregulation in head and neck squamous cell carcinoma: a potential prognostic biomarker associated with immune infiltration	4
Comparison of exploratory behavior of male and female woodlice (Armadillidium vulgare)	4
The protective effect of melatonin supplementation against taxol-induced testicular cytotoxicity in adult rats	4
Experimental study of local anesthetic and antiarrhythmic activities of fluorinated ethynylpiperidine derivatives	4
Tracking immune dysregulation in COVID-19: lymphocyte dynamics from hospitalization to recovery	4
Features of lumbar spine texture extracted from routine MRI correlate with bone mineral density and can potentially differentiate patients with and without fragility fractures in the spine	4
Circulating JKAP levels may correlate with postpartum anxiety and depression through its interaction with T helper 17 cells	4
Relationship between resting augmentation index and spontaneous cardiac baroreflex sensitivity during handgrip exercise in postmenopausal women	4