OOIR: Observatory of International Research

Papers

(The TQCC of Brazilian Journal of Medical and Biological Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria	20
Eight-year change in carotid intima-media thickness and associated risk factors in adults with and without psoriasis - the ELSA-Brasil cohort study	20
Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone	20
Erratum notice for: “Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria” [Braz J Med Biol Res 2023: 56, e12894]	18
The dynamic changes in quantitative parameters of diffusion-weighted imaging at different b-values in a prostate cancer mouse model and their correlation with histopathology parameters	17
ACE gene polymorphisms (rs4340) II and DI are more responsive to the ergogenic effect of caffeine than DD on aerobic power, heart rate, and perceived exertion in a homogeneous Brazilian group of adole	16
Volumetric analysis of the damage and response of non-invasive brain stimulation in patients with spatial neglect after stroke: a subgroup analysis of the ELETRON trial	16
The role of ferroptosis in vascular endothelial cells and its role in the pathogenesis of cervical spondylosis of vertebral artery type: a comprehensive review	15
Telomerase inhibitors TMPyP4 and thymoquinone decreased cell proliferation and induced cell death in the non-small cell lung cancer cell line LC-HK2, modifying the pattern of focal adhesion	14
Cognitive behavioral stress management effectively facilitates neurologic recovery, alleviates mental distress, and elevates health status in acute ischemic stroke patients	13
Anti-inflammatory, procollagen, and wound repair properties of topical insulin gel	13
Low-intensity pulsed ultrasound inhibits chondrocyte senescence by inhibiting PI3K/AKT/mTOR signaling	13
Ovarian hormones influence immune response to liver ischemia-reperfusion	12
Prediction of early myocardial damage in obstructive sleep apnea patients using combined logistic regression and QUEST decision tree models	11
Chemical stability and compatibility of acetaminophen injection with six common opioid drugs: implications for clinical use	11
Resveratrol as a cardioprotective adjuvant for 5-fluorouracil in the treatment of gastric cancer cells	10
Erratum notice for: “Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways” [Braz J Med Biol Res 2020;53(2): e8793]	10
Is near-infrared spectroscopy a promising predictor for early intracranial hemorrhage diagnosis in the Emergency Department?	10
In vitro effects of lapachol and β-lapachone against Leishmania amazonensis	10
Brief results of heterotopic xenotransplantation of meningioma into the peritoneum of Wistar rats: an experimental study	10
Evaluation of cytokine levels in HIV-infected individuals on therapy with tenofovir, lamivudine, and dolutegravir	10
Effects of N-butanol extract of Amygdalus mongolica on rats with bleomycin‐induced pulmonary fibrosis based on metabolomics	10
Nutrition management by a multidisciplinary team for prevention of nutritional deficits and morbidity following esophagectomy	9
GSK3B inhibition reduced cervical cancer cell proliferation and migration by modulating the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition	9
Epidemiological and clinical factors of breast cancer in a population of mostly Afro-descendant women	9

Eugenol inhibits preadipocyte differentiation and lipid accumulation via upregulating ATF3	9
Effects of imposed and self-selected exercise on perceptual and affective responses, muscle function, quality, and functionality of strength training in older women and men: a randomized trial	9
Sorting nexin 10 knockdown: new strategies for alleviating sepsis-associated acute lung injury	9
The role and mechanisms of cordycepin in inhibiting cancer cells	9
Barriers to patient recruitment in a poststroke neurorehabilitation multicenter trial in Brazil	9
Quantifying lactulose and mannitol using LC-MS/MS in a clinical study of children with environmental enteric disease	9
Electroacupuncture alleviates Parkinson's disease-related pain by inhibiting microglial NLRP3-ASC inflammasome in the amygdala	9
The duration-dependent and sex-specific effects of neonatal sevoflurane exposure on cognitive function in rats	9
Didymin protects against polystyrene nanoplastic-induced hepatic damage in male albino rats by modulation of Nrf-2/Keap-1 pathway	9
Sulfasalazine prevents lung injury due to intra-abdominal sepsis in rats: possible role of Nrf2 and angiopoietin-2	9
Mental stress induces endothelial dysfunction by AT1R-mediated redox imbalance in overweight/obese men	9
Prevalence and risk factors for falls among older Chinese adults in the community: findings from the CLHLS study	8
CAR-T therapy for gastrointestinal cancers: current status, challenges, and future directions	8
A U-shaped relationship between sleep duration and tinnitus incidence: analysis of 13,871 participants from NHANES	8
Machine learning approaches and genetic determinants that influence the development of type 2 diabetes mellitus: a genetic association study in Brazilian patients	8
Neurocognitive effects of proanthocyanidin in Alzheimer's disease: a systematic review of preclinical evidence	8
The essential role of adenine nucleotide translocase 4 on male reproductive function in mice	8
Fatty acid profile and effect of Plukenetia volubilis L. (sacha inchi) oil on lipid metabolism in rats fed a high-fat diet	8
Diagnostic value of serum inflammatory markers in predicting early refractoriness of transarterial chemoembolization in patients with Barcelona Clinic Liver Cancer Stage 0, A, and B hepatocellular car	7
Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells	7
1H-NMR-based metabolomics reveals that prior exercise modulates metabolic changes in the cerebral cortex and hippocampus in sleep-deprived mice	7
Assessing the reaction to and efficacy of the Screener drug discovery and development board game as a pedagogical tool in postgraduate courses	7
Unveiling immune mechanisms and potential biomarkers in intervertebral disc degeneration through integrated analysis	7
Trifolirhizin improves the hyperproliferation and excessive inflammatory response in human HaCaT keratinocytes and ameliorates skin lesions in psoriasis-like mouse models	7
Giant uterine tumor and miscarriage: how to proceed?	7
H2S inhibits high glucose-induced osteoblast injury by inhibiting ferroptosis in diabetic osteoporosis in vitro	7
Puerarin protects the fatty liver from ischemia-reperfusion injury by regulating the PI3K/AKT signaling pathway	7
Effects of endurance exercise training on endoplasmic reticulum stress in pancreatic islets of obese mice	6
Self-reported carbohydrate supercompensation and supplementation strategies adopted by Olympic triathlon athletes	6
Synergy between isobavachalcone and doxorubicin suppressed the progression of anaplastic thyroid cancer through ferroptosis activation	6
Effect of high-intensity childhood games on heart rate variability, saliva leptin concentrations, and body composition in children	6
Interplay between volemic balance and the intestinal tract: insights on biomarkers and diagnostic tests used to assess intestinal morphofunctional barrier	6
Angiotensin receptor-neprilysin inhibitors and cardiac remodeling	6
Data-driven decision making for the screening of cognitive impairment in primary care: a machine learning approach using data from the ELSA-Brasil study	6
The body weight-walking distance product as a superior parameter in determining the VO2 on-kinetics in coronary artery disease	6
Deoxycholic acid aggravates necrotizing enterocolitis through downregulation of mesenchymal-epithelial transition factor expression	6
Extraction and characterization of collagen from the skin of Amazonian freshwater fish pirarucu	6
Integrative analyses of genetic characteristics associated with skeletal endothelial cells	6
Effects of an early rehabilitation program for adult cystic fibrosis patients during hospitalization: a randomized clinical trial	6
Upregulation of PGC-1α expression by pioglitazone mediates prevention of sepsis-induced acute lung injury	6
Luteolin ameliorates loperamide-induced functional constipation in mice	6
N-glycosylation of ACTRIIB enhances protein stability leading to rapid cell proliferation and strong resistance to docetaxel in nasopharyngeal carcinoma	5
ZC3H12D upregulation in head and neck squamous cell carcinoma: a potential prognostic biomarker associated with immune infiltration	5
Disulfidptosis modification patterns are involved in the immune microenvironment regulation of septic acute respiratory distress syndrome	5
MMP9 regulates osteogenesis and MMP2 expression through the TGF-β1/SMAD2/3 signaling pathway in lipopolysaccharide-induced osteoblasts	5
Salvia miltiorrhiza: insights on the protective effect and mechanism of myocardial ischemia-reperfusion injury	5
Precision application of target-controlled infusion of esketamine combined with sufentanil in anesthesia for thoracoscopic surgery and its effect on hemodynamics, postoperative pain, and safety	5
FNDC5/Irisin in dementia and cognitive impairment: update and novel perspective	5
Cortical thickness is related to working memory performance after non-invasive brain stimulation	5
Quality of life and functional capacity in depressive patients on hemodialysis: a systematic review and meta-analysis	5

Saccharomyces boulardii supplementation does not affect anaerobic power gain induced by short-term sprint interval training in physically active individuals	5
Systemic effects of oral tolerance improve the healing of several and concomitant wounds on different parts of the body	5
Biomarker-based prediction of radial artery occlusion after cardiac catheterization	5
Impact of targeted nursing care and nutritional support on clinical outcomes in diabetic nephropathy patients undergoing maintenance hemodialysis	5
Loneliness, spiritual well-being, and death perception, as well as their risk factors in urological cancer patients	5
Bioinformatic features and immunological response of recombinant antigen CTLA4-IgV-EgG1Y162 against Echinococcus granulosus	5
Investigations on the cytotoxicity and antimicrobial activities of terezine E and 14-hydroxyterezine D	5
Toxic effects of Arianor Ebony hair dye on human cells	4
Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line	4
Relationship between resting augmentation index and spontaneous cardiac baroreflex sensitivity during handgrip exercise in postmenopausal women	4
Osteogenic mechanism of deciduous teeth periodontal ligament stem cells in inflammatory environment	4
Assessing multiple factors affecting the gut microbiome structure of very preterm infants	4
Efficacy of convalescent plasma in hospitalized COVID-19 patients: findings from a controlled trial	4
Association among cardiopulmonary and metabolic rehabilitation, arrhythmias, and myocardial ischemia responses of patients with HFpEF or HFmrEF	4
Comparison of exploratory behavior of male and female woodlice (Armadillidium vulgare)	4
CETP gene polymorphisms and haplotypes are explanatory variables for HDL cholesterol level in sickle cell disease	4
Knockout of Mucin 1 inhibits the proliferation, migration, and invasion of human MDA-MB-231 cells by blocking autophagy flow	4
Role of cyclooxygenases 1 and 2 in the maintenance of colonic mucosal integrity in an experimental colitis model	4
Acupuncture for generalized anxiety disorder: a study protocol for a randomized controlled trial	4
Circulating JKAP levels may correlate with postpartum anxiety and depression through its interaction with T helper 17 cells	4
Minimally invasive autopsy as a useful tool for RNA extraction in molecular pathology of lung diseases	4
Chrysin induces cell death and inhibits migration and invasion in squamous cervical carcinoma using a three-dimensional cell culture model	4
Tracking immune dysregulation in COVID-19: lymphocyte dynamics from hospitalization to recovery	4
A model for preservation of thymocyte-depleted thymus	4
Aerobic capacity evaluation of Sprague Dawley rats in treadmill running: comparison between protocols	4
Brazilian science through the looking glass: a scientometric perspective from within and beyond	4
Effect of mind map-guided nursing on pain control after transurethral resection of the prostate	4
Experimental study of local anesthetic and antiarrhythmic activities of fluorinated ethynylpiperidine derivatives	4
Evaluation of oxidative stress markers in ethanol users	4
Metformin attenuates fructose-induced pulmonary fibrosis, possibly through the involvement of the TRPC6 channel	4
Moderate physical exercise and ATP modulate the P2X7 receptor and improve cisplatin-induced gastric emptying delay in rats	4
Features of lumbar spine texture extracted from routine MRI correlate with bone mineral density and can potentially differentiate patients with and without fragility fractures in the spine	4
Biochanin A exerts an anti-inflammatory effect on adipose tissue and liver of ovariectomized obese mice	4
Factors associated with non-treatment of hypertension and gender differences at baseline in the ELSA-Brasil cohort	4
Genomic instability in long-term culture of human adipose-derived mesenchymal stromal cells	4
The role of the PKCζ/JNK signaling pathway in regulating the development of femoral head necrosis	4
Effects of long-term metformin administration associated with high-intensity interval training on physical performance, glycogen concentration, GLUT-4 content, and NMR-based metabolomics in healthy ra	4