OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Aspects of Medicine is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Editorial Board	247
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	204
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	192
The role of free fatty acid receptors activation in pancreatic disorders	178
The double-edged sword: How SARS-CoV-2 might fuel lung cancer: Investigating the potential oncogenic mechanisms of the novel coronavirus in lung carcinogenesis	150
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	116
Emerging and Re-emerging viruses as triggers of human endogenous retrovirus activation: Implications for aging and age-related pathologies	105
DNA melting analysis	100
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	96
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	85
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	79
Data structuring may prevent ambiguity and improve personalized medical prognosis	76
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	76
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	71
Interactions between pathological and functional amyloid: A match made in Heaven or Hell?	70
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	69
The crosstalk of neutrophil extracellular trap-inflammasome and their roles in disease progression	63
Bioactives and human health	58
Autophagy signaling mediated by non-coding RNAs: Impact on breast cancer progression and treatment	54
Viral pathogens in bone- and bone-marrow derived malignancies: Friends or foes?	48
Rodent genetically modified models of glaucoma	47
The bidirectional link between diabetes and pancreatic cancer: A diagnostic aid, risk factor, and potential target for future therapy	46
Glucose-derived posttranslational modification in cardiovascular disease	45
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies	43
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis	43

The thermodynamic hypothesis of protein aggregation	43
Editorial Board	42
Decoding driver and phenotypic genes in cancer: Unveiling the essence behind the phenomenon	41
Cross-talk between cancer and diabetes: Exploring shared molecular pathways in cellular metabolism and signaling	41
Molecular mechanisms of oxidative stress in asthma	40
Emerging technologies in personalized medicine	40
Strategies to deliver RNA by nanoparticles for therapeutic potential	38
Invasive fungal infections: An expanding and evolving threat	38
Influence of microbiota composition on the pathogenesis of type 2 diabetes: Physiological aspects	38
Computational methods in glaucoma research: Current status and future outlook	36
An updated systematic review about various effects of microplastics on cancer: A pharmacological and in-silico based analysis	35
Cellular and molecular mechanisms of allergic asthma	35
Viruses in gastrointestinal cancers: Molecular pathogenesis, oncogenic mechanisms, and translational perspectives	34
Neuroteratogenic mechanisms of Zika virus (ZIKV) infection: Insights into fetal brain development disruption and congenital Zika syndrome: A systematic review	34
The recent blooming of therapeutic aptamers	33
Multidimensional review of viral infectious ocular diseases: Post-Pandemic epidemiology and future directions for control	33
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases	33
Kinetic mechanisms for O2 binding to myoglobins and hemoglobins	33
Editorial Board	32
Editorial Board	32
Editorial Board	32
Mitophagy: A key regulator of radiotherapy resistance in the tumor immune microenvironment	32
Metabolic reprogramming shapes post-translational modification in macrophages	31
Molecular allergology approach to allergic asthma	30
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine	30
NRF2-mediated regulation of lipid pathways in viral infection	30
Irreversible post-translational modifications – Emerging cardiovascular risk factors	30
Antifungal prophylaxis and pre-emptive therapy: When and how?	30
The ocular immune system and Flaviviruses: A crossroad between defense and disease	30
Molecular mechanism involved in sarcopenia and frailty, diagnosis and therapy	29
Diet and exercise in frailty and sarcopenia. Molecular aspects	28
Testicular immunity	28
Role of hemoglobin structural-functional relationships in oxygen transport	28
Research advancements on sumoylation in gastrointestinal cancers	27
Frailty and biological age. Which best describes our aging and longevity?	27
Extracellular vesicles as personalized medicine	27
Corrigendum to: “Unveiling the P2X7 receptor: Exploring its mechanisms, pathogenic role in ocular diseases, and emerging therapeutic potential” [Mol. Aspect. Med. 105 (2025) 101389 https://doi.org/10.	27
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	26
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	26
Implications of obesity-mediated cellular dysfunction and adipocytokine signaling pathways in the pathogenesis of osteoarthritis	24
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	24
Hemoglobin allostery and pharmacology	24
From hemoglobin allostery to hemoglobin-based oxygen carriers	24
Are we getting closer to a successful neoantigen cancer vaccine?	24