OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Aspects of Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Editorial Board	276
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	243
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	231
The double-edged sword: How SARS-CoV-2 might fuel lung cancer: Investigating the potential oncogenic mechanisms of the novel coronavirus in lung carcinogenesis	202
Emerging and Re-emerging viruses as triggers of human endogenous retrovirus activation: Implications for aging and age-related pathologies	172
Editorial Board	129
DNA melting analysis	124
The role of free fatty acid receptors activation in pancreatic disorders	110
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	106
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	102
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	100
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	96
The crosstalk of neutrophil extracellular trap-inflammasome and their roles in disease progression	96
Interactions between pathological and functional amyloid: A match made in Heaven or Hell?	95
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	83
Data structuring may prevent ambiguity and improve personalized medical prognosis	69
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	66
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	65
Bioactives and human health	62
Glucose-derived posttranslational modification in cardiovascular disease	60
Autophagy signaling mediated by non-coding RNAs: Impact on breast cancer progression and treatment	55
Vav3, a potential diagnostic and prognostic marker of diabetes, regulates glycolipid metabolism	52
The bidirectional link between diabetes and pancreatic cancer: A diagnostic aid, risk factor, and potential target for future therapy	52
The thermodynamic hypothesis of protein aggregation	50
Viral pathogens in bone- and bone-marrow derived malignancies: Friends or foes?	46

Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis	45
Rodent genetically modified models of glaucoma	45
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies	45
Editorial Board	43
Cross-talk between cancer and diabetes: Exploring shared molecular pathways in cellular metabolism and signaling	43
Decoding driver and phenotypic genes in cancer: Unveiling the essence behind the phenomenon	42
Emerging technologies in personalized medicine	42
Invasive fungal infections: An expanding and evolving threat	41
Molecular mechanisms of oxidative stress in asthma	41
Computational methods in glaucoma research: Current status and future outlook	41
Cellular and molecular mechanisms of allergic asthma	40
Influence of microbiota composition on the pathogenesis of type 2 diabetes: Physiological aspects	40
An updated systematic review about various effects of microplastics on cancer: A pharmacological and in-silico based analysis	38
Multidimensional review of viral infectious ocular diseases: Post-Pandemic epidemiology and future directions for control	38
Neuroteratogenic mechanisms of Zika virus (ZIKV) infection: Insights into fetal brain development disruption and congenital Zika syndrome: A systematic review	37
Mitophagy: A key regulator of radiotherapy resistance in the tumor immune microenvironment	37
Viruses in gastrointestinal cancers: Molecular pathogenesis, oncogenic mechanisms, and translational perspectives	37
The recent blooming of therapeutic aptamers	36
Editorial Board	36
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases	36
Editorial Board	34
Decoding emerging viral sepsis: Molecular crosstalk, dysregulation, and precision strategies	33
Editorial Board	33
Advances in sperm transcription and translation activities: From traditional views to new discoveries	33
The ocular immune system and Flaviviruses: A crossroad between defense and disease	32
NRF2-mediated regulation of lipid pathways in viral infection	32
Molecular allergology approach to allergic asthma	32
Metabolic reprogramming shapes post-translational modification in macrophages	32
Molecular mechanism involved in sarcopenia and frailty, diagnosis and therapy	29
Antifungal prophylaxis and pre-emptive therapy: When and how?	29
The multiorgan crosstalk network of the liver-brain axis: From molecular mechanisms to emerging therapeutic targets	28
Diet and exercise in frailty and sarcopenia. Molecular aspects	28
Testicular immunity	28
Extracellular vesicles as personalized medicine	28
Irreversible post-translational modifications – Emerging cardiovascular risk factors	28
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	27
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	27
Corrigendum to: “Unveiling the P2X7 receptor: Exploring its mechanisms, pathogenic role in ocular diseases, and emerging therapeutic potential” [Mol. Aspect. Med. 105 (2025) 101389 https://doi.org/10.	27
Implications of obesity-mediated cellular dysfunction and adipocytokine signaling pathways in the pathogenesis of osteoarthritis	27
Serine metabolism in the central nervous system: advances and challenges on a conditionally essential amino acid	27
Research advancements on sumoylation in gastrointestinal cancers	26
Systems to model the personalized aspects of microbiome health and gut dysbiosis	26
Frailty and biological age. Which best describes our aging and longevity?	26
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	26
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system	25
The folding and misfolding of multidomain proteins	25
Are we getting closer to a successful neoantigen cancer vaccine?	25
Post-translational modifications: Bridging viral infections and inflammatory bowel disease	24
Caspase mechanisms in the regulation of inflammation	24
Protein and RNA chaperones	23

Cardiovascular impact of emerging and Re-emerging Viruses: Pathophysiological mechanisms, diagnosis, and management with a pediatric focus	23
Pathological implication of protein post-translational modifications in cancer	23
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics	22
Frustration in physiology and molecular medicine	22
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota	22
Molecular aspects of exposome and metabolic diseases	21
Ubiquitin proteasome system and glaucoma: A survey of genetics and molecular biology studies supporting a link with pathogenic and therapeutic relevance	20
Avenues for post-translational protein modification prevention and therapy	20
Editorial: Honoring Dr. Angelo Azzi's legacy and expanding the horizons of Molecular Aspects of Medicine	20
The multifunctionality of the caspase family of proteases: A new perspective beyond cell death	19
When to suspect and how properly early detect and treat patients with endemic mycoses	19
Modern methods of molecular diagnostics	19
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases	19
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects	18
Adiponectin: its role in diabetic and pancreatic cancer	18
Impact of type 2 diabetes on malignancies of the female reproductive system	17
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications	17
Cancer vaccines: Target antigens, vaccine platforms and preclinical models	17
Nanoformulations for dismantling fungal biofilms: The latest arsenals of antifungal therapy	17
Editorial Board	16
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis	16
Circulating tumor cells as liquid biopsy markers in cancer patients	16
Editorial Board	16
Current and emerging sequencing-based tools for precision cancer medicine	16
Organ Fibrosis: Emerging diagnostic and therapeutic strategies	16
Molecular aspects of optic nerve autophagy in glaucoma	16
Diabetes and male fertility disorders	15
Vaccination against Helicobacter pylori – An approach for cancer prevention?	15
Insights into Women's health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers	15
Editorial Board	14
Hepatitis C virus chronicity and oncogenic potential: Vaccine development progress	14
Diagnostic and therapeutic potential of protease inhibition	14
Advances in understanding glaucoma pathogenesis: A multifaceted molecular approach for clinician scientists	13
Health and nutrition beyond essential nutrients: The evolution of the bioactives concept for human health	13
Editorial Board	13
Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies	13
The role of the microbiota in glaucoma	12
Siglecs in health and disease	12
Editorial Board	12
The bone-muscle unit: from mechanical coupling to soluble factors-mediated signaling	12
Molecular aspects of asthma	11
Impact of Siglecs on autoimmune diseases	11
Vaccines for breast cancer prevention: Are we there yet?	11
Disentangling the nutrition-microbiota liaison in inflammatory bowel disease	10
The uniqueness of on-demand male contraception	10
Recent advances in intestinal fibrosis	10
Beyond target cell death – Granzyme serine proteases in health and disease	10
Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies	10
In vitro high-content tissue models to address precision medicine challenges	10
A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics	10
Pharmacological reprogramming of plitidepsin as a SARS-CoV-2 inhibitor	10
Genetic rodent models of glaucoma in representing disease phenotype and insights into the pathogenesis	10
Editorial Board	9
Editorial Board	9
Have safety and efficacy assessments of bioactives come of age?	9