OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Aspects of Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	286
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	253
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	238
Editorial Board	206
DNA melting analysis	183
The double-edged sword: How SARS-CoV-2 might fuel lung cancer: Investigating the potential oncogenic mechanisms of the novel coronavirus in lung carcinogenesis	132
The role of free fatty acid receptors activation in pancreatic disorders	128
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	113
Emerging and Re-emerging viruses as triggers of human endogenous retrovirus activation: Implications for aging and age-related pathologies	109
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	108
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	105
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	102
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	101
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	96
Advancing precision medicine in pancreatic cancer using novel biomarkers and clinical targets	86
Beyond 100 years of vitamin E and related molecules – Milestones and open challenges	70
Interactions between pathological and functional amyloid: A match made in Heaven or Hell?	69
Data structuring may prevent ambiguity and improve personalized medical prognosis	69
The crosstalk of neutrophil extracellular trap-inflammasome and their roles in disease progression	63
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	62
Autophagy signaling mediated by non-coding RNAs: Impact on breast cancer progression and treatment	58
Vav3, a potential diagnostic and prognostic marker of diabetes, regulates glycolipid metabolism	55
The bidirectional link between diabetes and pancreatic cancer: A diagnostic aid, risk factor, and potential target for future therapy	55
Viral pathogens in bone- and bone-marrow derived malignancies: Friends or foes?	53
The thermodynamic hypothesis of protein aggregation	49

Rodent genetically modified models of glaucoma	49
Glucose-derived posttranslational modification in cardiovascular disease	48
Bioactives and human health	48
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis	46
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies	46
Editorial Board	45
Decoding driver and phenotypic genes in cancer: Unveiling the essence behind the phenomenon	45
Emerging technologies in personalized medicine	43
Cross-talk between cancer and diabetes: Exploring shared molecular pathways in cellular metabolism and signaling	43
Invasive fungal infections: An expanding and evolving threat	42
Molecular mechanisms of oxidative stress in asthma	42
Computational methods in glaucoma research: Current status and future outlook	42
Influence of microbiota composition on the pathogenesis of type 2 diabetes: Physiological aspects	41
Cellular and molecular mechanisms of allergic asthma	39
Multidimensional review of viral infectious ocular diseases: Post-Pandemic epidemiology and future directions for control	39
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases	38
Viruses in gastrointestinal cancers: Molecular pathogenesis, oncogenic mechanisms, and translational perspectives	38
Neuroteratogenic mechanisms of Zika virus (ZIKV) infection: Insights into fetal brain development disruption and congenital Zika syndrome: A systematic review	38
The recent blooming of therapeutic aptamers	38
An updated systematic review about various effects of microplastics on cancer: A pharmacological and in-silico based analysis	36
Editorial Board	36
Mitophagy: A key regulator of radiotherapy resistance in the tumor immune microenvironment	36
Editorial Board	34
Editorial Board	34
NRF2-mediated regulation of lipid pathways in viral infection	33
Decoding emerging viral sepsis: Molecular crosstalk, dysregulation, and precision strategies	33
Molecular allergology approach to allergic asthma	33
The ocular immune system and Flaviviruses: A crossroad between defense and disease	32
Antifungal prophylaxis and pre-emptive therapy: When and how?	31
Advances in sperm transcription and translation activities: From traditional views to new discoveries	30
Metabolic reprogramming shapes post-translational modification in macrophages	30
Irreversible post-translational modifications – Emerging cardiovascular risk factors	29
Molecular mechanism involved in sarcopenia and frailty, diagnosis and therapy	29
Extracellular vesicles as personalized medicine	29
The multiorgan crosstalk network of the liver-brain axis: From molecular mechanisms to emerging therapeutic targets	29
Corrigendum to: “Unveiling the P2X7 receptor: Exploring its mechanisms, pathogenic role in ocular diseases, and emerging therapeutic potential” [Mol. Aspect. Med. 105 (2025) 101389 https://doi.org/10.	28
Testicular immunity	28
Diet and exercise in frailty and sarcopenia. Molecular aspects	28
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	27
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	27
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	27
Research advancements on sumoylation in gastrointestinal cancers	27
Serine metabolism in the central nervous system: advances and challenges on a conditionally essential amino acid	26
Frailty and biological age. Which best describes our aging and longevity?	26
Implications of obesity-mediated cellular dysfunction and adipocytokine signaling pathways in the pathogenesis of osteoarthritis	26
Protein and RNA chaperones	25
Systems to model the personalized aspects of microbiome health and gut dysbiosis	25
Post-translational modifications: Bridging viral infections and inflammatory bowel disease	25
Are we getting closer to a successful neoantigen cancer vaccine?	25
Pathological implication of protein post-translational modifications in cancer	24

Caspase mechanisms in the regulation of inflammation	24
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system	23
Ubiquitin proteasome system and glaucoma: A survey of genetics and molecular biology studies supporting a link with pathogenic and therapeutic relevance	23
The folding and misfolding of multidomain proteins	23
Molecular aspects of exposome and metabolic diseases	22
Cardiovascular impact of emerging and Re-emerging Viruses: Pathophysiological mechanisms, diagnosis, and management with a pediatric focus	22
Avenues for post-translational protein modification prevention and therapy	21
Editorial: Honoring Dr. Angelo Azzi's legacy and expanding the horizons of Molecular Aspects of Medicine	20
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics	20
When to suspect and how properly early detect and treat patients with endemic mycoses	20
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases	20
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota	19
Frustration in physiology and molecular medicine	19
Adiponectin: its role in diabetic and pancreatic cancer	18
Modern methods of molecular diagnostics	18
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications	18
Circulating tumor cells as liquid biopsy markers in cancer patients	17
Cancer vaccines: Target antigens, vaccine platforms and preclinical models	17
Impact of type 2 diabetes on malignancies of the female reproductive system	17
The multifunctionality of the caspase family of proteases: A new perspective beyond cell death	17
Nanoformulations for dismantling fungal biofilms: The latest arsenals of antifungal therapy	17
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects	16
Editorial Board	16
Organ Fibrosis: Emerging diagnostic and therapeutic strategies	16
Editorial Board	16
Molecular aspects of optic nerve autophagy in glaucoma	16
Diabetes and male fertility disorders	15
Current and emerging sequencing-based tools for precision cancer medicine	15
Insights into Women's health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers	15
Health and nutrition beyond essential nutrients: The evolution of the bioactives concept for human health	14
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis	14
Hepatitis C virus chronicity and oncogenic potential: Vaccine development progress	14
Vaccination against Helicobacter pylori – An approach for cancer prevention?	14
Advances in understanding glaucoma pathogenesis: A multifaceted molecular approach for clinician scientists	14
Editorial Board	14
Editorial Board	13
Siglecs in health and disease	13
Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies	13
The bone-muscle unit: from mechanical coupling to soluble factors-mediated signaling	13
Diagnostic and therapeutic potential of protease inhibition	13
The role of the microbiota in glaucoma	13
Recent advances in intestinal fibrosis	12
Editorial Board	12
Vaccines for breast cancer prevention: Are we there yet?	12
Molecular aspects of asthma	12
Genetic rodent models of glaucoma in representing disease phenotype and insights into the pathogenesis	11
Pharmacological reprogramming of plitidepsin as a SARS-CoV-2 inhibitor	10
The uniqueness of on-demand male contraception	10
A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics	10
Impact of Siglecs on autoimmune diseases	10
In vitro high-content tissue models to address precision medicine challenges	10
Beyond target cell death – Granzyme serine proteases in health and disease	10
Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies	10
Have safety and efficacy assessments of bioactives come of age?	10
Disentangling the nutrition-microbiota liaison in inflammatory bowel disease	9
Editorial Board	9
Editorial Board	9
Editorial Board	9