Molecular Aspects of Medicine

Papers
(The median citation count of Molecular Aspects of Medicine is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The NLRP3 inflammasome: Mechanism of action, role in disease and therapies242
Autophagy in liver diseases: A review177
An overview of the non-canonical inflammasome175
NK cells and ILCs in tumor immunotherapy154
Molecular mechanisms of oxidative stress in asthma128
Cellular and molecular mechanisms of allergic asthma98
Immunometabolic control of trained immunity81
NLRP12 in innate immunity and inflammation81
Pathological implication of protein post-translational modifications in cancer70
The role of O-glycosylation in human disease68
Pathobiology of Japanese encephalitis virus infection63
Targeting O-GlcNAcylation to develop novel therapeutics62
Neuronal autophagy and mitophagy in Parkinson's disease60
Immunobiology and structural biology of AIM2 inflammasome58
The NAIP/NLRC4 inflammasome in infection and pathology57
NLRP6 inflammasome53
Ageing – Oxidative stress, PTMs and disease52
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming50
Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential49
Identification and characterization of post-translational modifications: Clinical implications49
Polysialylation and disease46
Lipid metabolism in colon cancer: Role of Liver X Receptor (LXR) and Stearoyl-CoA Desaturase 1 (SCD1)41
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies39
Macroautophagy and aging: The impact of cellular recycling on health and longevity38
Siglec receptors as new immune checkpoints in cancer36
Revealing macropinocytosis using nanoparticles36
Extracellular vesicles as personalized medicine35
Dysregulation of host cell calcium signaling during viral infections: Emerging paradigm with high clinical relevance34
N-glycans as functional effectors of genetic and epigenetic disease risk33
Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering33
The human inflammasomes32
Biological mechanisms and therapeutic relevance of the gasdermin family31
Nuclear receptors in the kidney during health and disease31
Structural and functional diversity of neutrophil glycosylation in innate immunity and related disorders31
Role of autophagy in muscle disease30
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota30
Mitochondria orchestrate macrophage effector functions in atherosclerosis30
Diseases related to Notch glycosylation28
To protect or adversely affect? The dichotomous role of the NLRP1 inflammasome in human disease28
True significance of N-acetylglucosaminyltransferases GnT-III, V and α1,6 fucosyltransferase in epithelial-mesenchymal transition and cancer28
PPARδ and its ligand erucic acid may act anti-tumoral, neuroprotective, and myelin protective in neuroblastoma, glioblastoma, and Parkinson's disease26
Thalassemias: from gene to therapy26
New insights into the role of autophagy in retinal and eye diseases25
Nuclear receptors: Key regulators of somatic cell functions in the ovulatory process24
Unlocking the bacterial membrane as a therapeutic target for next-generation antimicrobial amphiphiles24
Moments in autophagy and disease: Past and present24
Corticosteroid resistance in asthma: Cellular and molecular mechanisms23
Altitude acclimatization, hemoglobin-oxygen affinity, and circulatory oxygen transport in hypoxia23
Fetoplacental vasculature as a model to study human cardiovascular endocrine disruption22
The need for precision nutrition, genetic variation and resolution in Covid-19 patients22
Cathepsin V: Molecular characteristics and significance in health and disease22
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis22
The peroxidatic activities of Myoglobin and Hemoglobin, their pathological consequences and possible medical interventions22
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe22
Viral proteases as therapeutic targets22
Molecular and structural facets of c-di-GMP signalling associated with biofilm formation in Pseudomonas aeruginosa22
From hemoglobin allostery to hemoglobin-based oxygen carriers22
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics21
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies21
Smoking for two- effects of tobacco consumption on placenta20
Role of hemoglobin structural-functional relationships in oxygen transport20
Functional consequences of lead and mercury exposomes in the heart19
Nuclear receptors, the aryl hydrocarbon receptor, and macrophage function19
Neutrophils at the crossroads of acute viral infections and severity19
Immunometabolic control of hematopoiesis19
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system19
Extracellular vesicles in the glioblastoma microenvironment: A diagnostic and therapeutic perspective19
Anthocyanin actions at the gastrointestinal tract: Relevance to their health benefits18
The dual function of ILC2: From host protection to pathogenic players in type 2 asthma18
Discovery, classification, evolution and diversity of Siglecs18
Cysteine cathepsins: A long and winding road towards clinics18
Metabolomics in asthma: A platform for discovery18
Hemoglobin: Multiple molecular interactions and multiple functions. An example of energy optimization and global molecular organization17
Human colonic catabolism of dietary flavan-3-ol bioactives17
Neuroglobin, clues to function and mechanism17
The changing epidemiology of fungal infections16
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications16
Proteostasis in aging-associated ocular disease16
Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus16
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases15
Nanodelivery of STING agonists against cancer and infectious diseases15
Nicotinic receptors: From protein allostery to computational neuropharmacology15
Controlled release nanoplatforms for three commonly used chemotherapeutics15
Estrogen Receptor on the move: Cistromic plasticity and its implications in breast cancer15
Chaperone-mediated autophagy and disease: Implications for cancer and neurodegeneration15
Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies15
Recent advances, status, and opportunities of magneto-electric nanocarriers for biomedical applications15
The influence of the dietary exposome on oxidative stress in pregnancy complications15
From bench side to clinic: Potential and challenges of RNA vaccines and therapeutics in infectious diseases15
Circadian rhythms in the tissue-specificity from metabolism to immunity: insights from omics studies15
Interplay between hypoxia and inflammation contributes to the progression and severity of respiratory viral diseases14
Hemoglobin allostery and pharmacology14
The placental exposome, placental epigenetic adaptations and lifelong cardio-metabolic health14
Exploiting pilus-mediated bacteria-host interactions for health benefits14
Metabolic adaptations of cells at the vascular-immune interface during atherosclerosis13
Asthma COPD overlap: Insights into cellular and molecular mechanisms13
Kinetic mechanisms for O2 binding to myoglobins and hemoglobins13
Caspase mechanisms in the regulation of inflammation13
Programming of weight and obesity across the lifecourse by the maternal metabolic exposome: A systematic review12
Beyond target cell death – Granzyme serine proteases in health and disease12
The evolving regulatory landscape in regenerative medicine12
Impact of Siglecs on autoimmune diseases12
ILC in chronic inflammation, cancer and targeting with biologicals12
Impact of hemoglobin biophysical studies on molecular pathogenesis and drug therapy for sickle cell disease11
Diagnostic and therapeutic potential of protease inhibition11
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine11
New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology11
Measuring the intake of dietary bioactives: Pitfalls and how to avoid them11
Metabolic regulation of T lymphocyte motility and migration11
Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes11
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics11
Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies11
Kidney fibrosis: Emerging diagnostic and therapeutic strategies11
Molecular allergology approach to allergic asthma11
Chapter 5 – “Parkinson's disease – A role of non-enzymatic posttranslational modifications in disease onset and progression?”10
Immunometabolism of regulatory T cells in cancer10
The role of oxidized phospholipids in the development of disease10
Antifungal prophylaxis and pre-emptive therapy: When and how?10
Vaccines for HPV-associated diseases10
The role of the microbiota in glaucoma9
Irreversible post-translational modifications – Emerging cardiovascular risk factors9
Human sialoglycan ligands for immune inhibitory Siglecs9
Siglecs in allergy and asthma9
The subversion of toll-like receptor signaling by bacterial and viral proteases during the development of infectious diseases9
Vaccination against Helicobacter pylori – An approach for cancer prevention?9
Innate lymphoid cells (ILC) in SARS-CoV-2 infection9
Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders8
Roles of Siglecs in neurodegenerative diseases8
Truncated (2/2) hemoglobin: Unconventional structures and functional roles in vivo and in human pathogenesis8
Interplay between orphan nuclear receptors and androgen receptor-dependent or-independent growth signalings in prostate cancer7
Galectins in allergic inflammatory diseases7
Non-canonical functions of autophagy proteins in immunity and infection7
Non-canonical roles of Siglecs: Beyond sialic acid-binding and immune cell modulation7
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis7
Systems to model the personalized aspects of microbiome health and gut dysbiosis7
Mechanistic insights into dietary (poly)phenols and vascular dysfunction-related diseases using multi-omics and integrative approaches: Machine learning as a next challenge in nutrition research7
NK cell and ILC heterogeneity in colorectal cancer. New perspectives from high dimensional data7
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