OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Aspects of Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Editorial Board	239
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	179
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	178
ILC in chronic inflammation, cancer and targeting with biologicals	133
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	122
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	120
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	91
DNA melting analysis	87
Diseases related to Notch glycosylation	80
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	76
Data structuring may prevent ambiguity and improve personalized medical prognosis	71
Role of autophagy in muscle disease	66
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	66
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	65
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	65
Bioactives and human health	57
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies	57
Rodent genetically modified models of glaucoma	56
Antiviral therapeutics directed against RNA dependent RNA polymerases from positive-sense viruses	55
Glucose-derived posttranslational modification in cardiovascular disease	50
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis	49
Editorial Board	48
Emerging technologies in personalized medicine	47
Molecular mechanisms of oxidative stress in asthma	43
Computational methods in glaucoma research: Current status and future outlook	39

Strategies to deliver RNA by nanoparticles for therapeutic potential	39
Invasive fungal infections: An expanding and evolving threat	37
Cellular and molecular mechanisms of allergic asthma	36
An updated systematic review about various effects of microplastics on cancer: A pharmacological and in-silico based analysis	36
Kinetic mechanisms for O2 binding to myoglobins and hemoglobins	35
The recent blooming of therapeutic aptamers	35
Editorial Board	35
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases	35
Metabolic reprogramming shapes post-translational modification in macrophages	34
Innate lymphoid cells (ILC) in SARS-CoV-2 infection	34
Molecular allergology approach to allergic asthma	33
Antifungal prophylaxis and pre-emptive therapy: When and how?	33
NRF2-mediated regulation of lipid pathways in viral infection	33
Circadian rhythms in the tissue-specificity from metabolism to immunity: insights from omics studies	31
Testicular immunity	30
Diet and exercise in frailty and sarcopenia. Molecular aspects	30
Role of hemoglobin structural-functional relationships in oxygen transport	29
Irreversible post-translational modifications – Emerging cardiovascular risk factors	29
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine	27
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	27
Extracellular vesicles as personalized medicine	27
From hemoglobin allostery to hemoglobin-based oxygen carriers	26
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	26
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	26
Hemoglobin allostery and pharmacology	25
Frailty and biological age. Which best describes our aging and longevity?	25
Systems to model the personalized aspects of microbiome health and gut dysbiosis	25
Are we getting closer to a successful neoantigen cancer vaccine?	24
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system	24
Nicotinic receptors: From protein allostery to computational neuropharmacology	24
Inhibitory axes impacting on the activity and fate of Innate Lymphoid Cells	24
The folding and misfolding of multidomain proteins	23
NK cells and ILCs in tumor immunotherapy	23
Caspase mechanisms in the regulation of inflammation	23
Pathological implication of protein post-translational modifications in cancer	22
Ubiquitin proteasome system and glaucoma: A survey of genetics and molecular biology studies supporting a link with pathogenic and therapeutic relevance	22
When to suspect and how properly early detect and treat patients with endemic mycoses	22
Autophagy in liver diseases: A review	22
Molecular aspects of exposome and metabolic diseases	22
Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes	21
Nanoformulations for dismantling fungal biofilms: The latest arsenals of antifungal therapy	21
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota	21
Avenues for post-translational protein modification prevention and therapy	21
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics	21
Modern methods of molecular diagnostics	21
Galectins in allergic inflammatory diseases	20
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects	20
Hemoglobin: Multiple molecular interactions and multiple functions. An example of energy optimization and global molecular organization	20
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications	20
Circulating tumor cells as liquid biopsy markers in cancer patients	20

Non-canonical functions of autophagy proteins in immunity and infection	20
Controlled release nanoplatforms for three commonly used chemotherapeutics	19
Editorial Board	19
Cancer vaccines: Target antigens, vaccine platforms and preclinical models	19
Organ Fibrosis: Emerging diagnostic and therapeutic strategies	19
The functional role of the hemoglobin-water interface	18
Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders	18
Diabetes and male fertility disorders	18
Insights into Women's health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers	18
Molecular aspects of optic nerve autophagy in glaucoma	17
NK cell surveillance of hematological malignancies. Therapeutic implications and regulation by chemokine receptors	17
Current and emerging sequencing-based tools for precision cancer medicine	16
Vaccination against Helicobacter pylori – An approach for cancer prevention?	16
Health and nutrition beyond essential nutrients: The evolution of the bioactives concept for human health	15
Advances in understanding glaucoma pathogenesis: A multifaceted molecular approach for clinician scientists	15
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis	15
Hepatitis C virus chronicity and oncogenic potential: Vaccine development progress	15
Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies	15
Editorial-innate lymphoid cells, a new key component of the immune system	15
Diagnostic and therapeutic potential of protease inhibition	15
Editorial Board	15
Altitude acclimatization, hemoglobin-oxygen affinity, and circulatory oxygen transport in hypoxia	14
Molecular aspects of asthma	14
Editorial Board	14
Structural and functional diversity of neutrophil glycosylation in innate immunity and related disorders	14
The role of the microbiota in glaucoma	14
The uniqueness of on-demand male contraception	14
Siglecs in health and disease	14
Editorial Board	14
Vaccines for breast cancer prevention: Are we there yet?	14
Recent advances in intestinal fibrosis	13
Genetic rodent models of glaucoma in representing disease phenotype and insights into the pathogenesis	13
Impact of Siglecs on autoimmune diseases	13
Editorial Board	13
In vitro high-content tissue models to address precision medicine challenges	12
Have safety and efficacy assessments of bioactives come of age?	12
Editorial Board	12
Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies	12
Beyond target cell death – Granzyme serine proteases in health and disease	12
Editorial Board	12
Disentangling the nutrition-microbiota liaison in inflammatory bowel disease	12
A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics	12
Editorial Board	11
Editorial Board	11
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies	10
Molecular determinants of peaceful coexistence versus invasiveness of non-Typhoidal Salmonella: Implications in long-term side-effects	10
NK cell and ILC heterogeneity in colorectal cancer. New perspectives from high dimensional data	10
Revealing macropinocytosis using nanoparticles	10
Therapeutic strategies for glaucoma and optic neuropathies	10
Editorial on proteases in health and disease	9
Signalling pathways and cell death mechanisms in glaucoma: Insights into the molecular pathophysiology	9
Targeting O-GlcNAcylation to develop novel therapeutics	9
Kidney fibrosis: Emerging diagnostic and therapeutic strategies	9
Physiological and pathological aspects of epididymal sperm maturation	9
Editorial Board	9