Molecular Aspects of Medicine

Papers
(The median citation count of Molecular Aspects of Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
The NLRP3 inflammasome: Mechanism of action, role in disease and therapies202
Iron in infection and immunity186
An overview of the non-canonical inflammasome160
Autophagy in liver diseases: A review140
NK cells and ILCs in tumor immunotherapy135
Basics and principles of cellular and systemic iron homeostasis108
The Atlas of Inflammation Resolution (AIR)107
Molecular mechanisms of oxidative stress in asthma101
Iron: The cancer connection89
Cellular and molecular mechanisms of allergic asthma79
Immunometabolic control of trained immunity72
NLRP12 in innate immunity and inflammation72
Oral iron supplementation in iron-deficient women: How much and how often?64
Haptoglobin: From hemoglobin scavenging to human health62
The role of O-glycosylation in human disease55
Targeting O-GlcNAcylation to develop novel therapeutics53
The NAIP/NLRC4 inflammasome in infection and pathology51
Pathological implication of protein post-translational modifications in cancer50
Pathobiology of Japanese encephalitis virus infection49
Neuronal autophagy and mitophagy in Parkinson's disease49
NLRP6 inflammasome49
Immunobiology and structural biology of AIM2 inflammasome49
Intravenous iron supplementation therapy43
Ageing – Oxidative stress, PTMs and disease42
Polysialylation and disease41
Identification and characterization of post-translational modifications: Clinical implications37
Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential35
Lipid metabolism in colon cancer: Role of Liver X Receptor (LXR) and Stearoyl-CoA Desaturase 1 (SCD1)33
The changing landscape of iron deficiency32
N-glycans as functional effectors of genetic and epigenetic disease risk32
Genetic iron overload disorders30
Macroautophagy and aging: The impact of cellular recycling on health and longevity30
Dysregulation of host cell calcium signaling during viral infections: Emerging paradigm with high clinical relevance29
Structural and functional diversity of neutrophil glycosylation in innate immunity and related disorders28
Biological mechanisms and therapeutic relevance of the gasdermin family28
Nuclear receptors in the kidney during health and disease28
Siglec receptors as new immune checkpoints in cancer27
True significance of N-acetylglucosaminyltransferases GnT-III, V and α1,6 fucosyltransferase in epithelial-mesenchymal transition and cancer27
Revealing macropinocytosis using nanoparticles27
The roles of iron and HFE genotype in neurological diseases26
Iron overload and its impact on outcome of patients with hematological diseases26
PPARδ and its ligand erucic acid may act anti-tumoral, neuroprotective, and myelin protective in neuroblastoma, glioblastoma, and Parkinson's disease26
Mitochondria orchestrate macrophage effector functions in atherosclerosis25
To protect or adversely affect? The dichotomous role of the NLRP1 inflammasome in human disease25
Iron at the host-microbe interface25
The human inflammasomes25
Role of autophagy in muscle disease25
Extracellular vesicles as personalized medicine24
Moments in autophagy and disease: Past and present23
Diseases related to Notch glycosylation23
The need for precision nutrition, genetic variation and resolution in Covid-19 patients22
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies22
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota21
Molecular and structural facets of c-di-GMP signalling associated with biofilm formation in Pseudomonas aeruginosa21
Unlocking the bacterial membrane as a therapeutic target for next-generation antimicrobial amphiphiles21
Nuclear receptors: Key regulators of somatic cell functions in the ovulatory process21
Fetoplacental vasculature as a model to study human cardiovascular endocrine disruption21
New insights into the role of autophagy in retinal and eye diseases20
Thalassemias: from gene to therapy20
Viral proteases as therapeutic targets19
Altitude acclimatization, hemoglobin-oxygen affinity, and circulatory oxygen transport in hypoxia19
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming18
Corticosteroid resistance in asthma: Cellular and molecular mechanisms18
From hemoglobin allostery to hemoglobin-based oxygen carriers18
Role of hemoglobin structural-functional relationships in oxygen transport18
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system17
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe17
The dual function of ILC2: From host protection to pathogenic players in type 2 asthma17
Immunometabolic control of hematopoiesis17
Smoking for two- effects of tobacco consumption on placenta16
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics16
Neutrophils at the crossroads of acute viral infections and severity16
Cathepsin V: Molecular characteristics and significance in health and disease16
The peroxidatic activities of Myoglobin and Hemoglobin, their pathological consequences and possible medical interventions16
Functional consequences of lead and mercury exposomes in the heart15
Nuclear receptors, the aryl hydrocarbon receptor, and macrophage function15
Regulation of iron homeostasis: Lessons from mouse models15
Iron in health and disease14
Metabolomics in asthma: A platform for discovery14
Nanodelivery of STING agonists against cancer and infectious diseases14
Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus14
Interplay between hypoxia and inflammation contributes to the progression and severity of respiratory viral diseases13
Neuroglobin, clues to function and mechanism13
From bench side to clinic: Potential and challenges of RNA vaccines and therapeutics in infectious diseases13
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications13
Estrogen Receptor on the move: Cistromic plasticity and its implications in breast cancer13
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis13
Discovery, classification, evolution and diversity of Siglecs12
Hemoglobin: Multiple molecular interactions and multiple functions. An example of energy optimization and global molecular organization12
Circadian rhythms in the tissue-specificity from metabolism to immunity: insights from omics studies12
Cysteine cathepsins: A long and winding road towards clinics12
Nicotinic receptors: From protein allostery to computational neuropharmacology12
Exploiting pilus-mediated bacteria-host interactions for health benefits12
Asthma COPD overlap: Insights into cellular and molecular mechanisms12
ILC in chronic inflammation, cancer and targeting with biologicals12
Programming of weight and obesity across the lifecourse by the maternal metabolic exposome: A systematic review12
The influence of the dietary exposome on oxidative stress in pregnancy complications12
Human colonic catabolism of dietary flavan-3-ol bioactives12
Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering12
The placental exposome, placental epigenetic adaptations and lifelong cardio-metabolic health12
Chaperone-mediated autophagy and disease: Implications for cancer and neurodegeneration12
Kinetic mechanisms for O2 binding to myoglobins and hemoglobins11
Controlled release nanoplatforms for three commonly used chemotherapeutics11
Caspase mechanisms in the regulation of inflammation11
Recent advances, status, and opportunities of magneto-electric nanocarriers for biomedical applications11
Iron deficiency and supplementation in heart failure and chronic kidney disease11
Anthocyanin actions at the gastrointestinal tract: Relevance to their health benefits10
Metabolic regulation of T lymphocyte motility and migration10
Extracellular vesicles in the glioblastoma microenvironment: A diagnostic and therapeutic perspective10
Impact of Siglecs on autoimmune diseases10
Proteostasis in aging-associated ocular disease10
New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology10
Impact of hemoglobin biophysical studies on molecular pathogenesis and drug therapy for sickle cell disease10
Hemoglobin allostery and pharmacology10
Immunometabolism of regulatory T cells in cancer10
Molecular allergology approach to allergic asthma10
Beyond target cell death – Granzyme serine proteases in health and disease9
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine9
Metabolic adaptations of cells at the vascular-immune interface during atherosclerosis9
Innate lymphoid cells (ILC) in SARS-CoV-2 infection9
Diagnostic and therapeutic potential of protease inhibition9
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases8
Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders8
Chapter 5 – “Parkinson's disease – A role of non-enzymatic posttranslational modifications in disease onset and progression?”8
Protein synthesis in Mycobacterium tuberculosis as a potential target for therapeutic interventions8
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics8
The evolving regulatory landscape in regenerative medicine8
Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes8
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