Lab Animal

Article	Citations
A review of 28 free animal-tracking software applications: current features and limitations	63
Guideline for the Care and Use of Laboratory Animals in Iran	44
A fish is not a mouse: understanding differences in background genetics is critical for reproducibility	26
Shared and distinctive features of the gut microbiome of C57BL/6 mice from different vendors and production sites, and in response to a new vivarium	22
Nonhuman primate models for SARS-CoV-2 research: Consider alternatives to macaques	21
The chicken embryo as an in vivo experimental model for drug testing: Advantages and limitations	19
Phenotyping spontaneous locomotor activity in inbred and outbred mouse strains by using Digital Ventilated Cages	19
C. elegans: A biosensor for host–microbe interactions	16
Oral application of clozapine-N-oxide using the micropipette-guided drug administration (MDA) method in mouse DREADD systems	15
A practical guide to setting up pig models for cardiovascular catheterization, electrophysiological assessment and heart disease research	14
Annelid genomes: Enchytraeus crypticus, a soil model for the innate (and primed) immune system	14
The genomic landscape of canine diffuse large B-cell lymphoma identifies distinct subtypes with clinical and therapeutic implications	12
Of mice and zebrafish: the impact of the experimenter identity on animal behavior	9
Nonhuman primate models for SARS-CoV-2 research: Infrastructure needs for pandemic preparedness	8
Know Your Model: A brief history of making mutant mouse genetic models	7
Optimized protocols for sperm cryopreservation and in vitro fertilization in the rat	7
A mapping review of refinements to laboratory rat housing and husbandry	6
On the value of zebrafish outbred strains in neurobehavioral research	6
A systematic review of porcine models in translational pain research	6
Animal models to study the neurological manifestations of the post-COVID-19 condition	5
3R measures in facilities for the production of genetically modified rodents	5
Rats on the rise	5
Replacement of surgical vasectomy through the use of wild-type sterile hybrids	5
Crispants take the spotlight	5
In vivo potency assay for the screening of bioactive molecules on cartilage formation	5

New insights into the origin of amyloid plaques	5
Digital pathology in academia: Implementation and impact	4
What does a Culture of Care look like? Lessons learnt from a workshop survey	4
Keeping an eye on the human-animal interface	4
Gut microbiota drives disease variability in the DSS colitis mouse model	4
Constructing and programming a cost-effective murine running wheel with digital revolution counter	4
Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis	4
Using touchscreen-delivered cognitive assessments to address the principles of the 3Rs in behavioral sciences	4
On the road to refinement	4
Use surplus laboratory animals as animal feed	4
Impact of test chamber design on spontaneous behavioral responses of model crustacean zooplankton Artemia franciscana	4
Model matchmaking	3
Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging	3
A new mouse model to study late-onset Alzheimer’s disease	3
Plasma metabolomics supports non-fasted sampling for metabolic profiling across a spectrum of glucose tolerance in the Nile rat model for type 2 diabetes	3
Translational science: a survey of US biomedical researchers’ perspectives and practices	3
Animal models of male subfertility targeted on LanCL1-regulated spermatogenic redox homeostasis	3
Stem cell transplantation improves Parkinson’s disease in monkeys	3
Isolation drives reward-seeking in rats	3
Nonhuman primate models for SARS-CoV-2 Research: Managing demand for specific-pathogen-free (SPF) animals	3
Construction and evaluation of a clinically relevant model of septic arthritis	3
Medetomidine/midazolam/fentanyl narcosis alters cardiac autonomic tone leading to conduction disorders and arrhythmias in mice	3
Animal models, open science, & space-omics	3
On the past, present, and future of in vivo science	3
Battle of the sexes: who is more variable, and does it really matter?	3
Focal brainstem infarction in the adult rat	3
Development and characterization of a new swine model of invasive pneumococcal pneumonia	3
Long-awaited NIH working group report on animal research rigor: ‘a good start’	3
Culture and collaboration between the clinician-scientist and veterinary specialist: An essential interprofessional partnership in the translational sciences	2
Modeling ALS/FTD in mice: Updates on the C9orf72 BAC transgenic mice	2
Using mice from different breeding sites fails to improve replicability of results from single-laboratory studies	2
Mice on the move	2
Shared science’s time to shine	2
Chronic stress and inflammation	2
CSF: a key player in brain’s immunity	2
Early growth response 2 in the mPFC regulates mouse social and cooperative behaviors	2
Turning fifty	2
Investigating trajectories of aging using high-dimensional phenotyping in mice	2
Disproportional cardiovascular depressive effects of isoflurane: Serendipitous findings from a comprehensive re-visit in mice	2
Challenging current scientific practice: how a shift in research methodology could reduce animal use	2
A minimal metadata set (MNMS) to repurpose nonclinical in vivo data for biomedical research	2
Optimizing AAV delivery to the brain	2
New insights into C9ORF72-ALS/FTD using C.elegans	2
More monkey models for studying COVID-19	2
A new mouse model to study miRNA biology	1
Housing and husbandry impact mouse phenotypes	1
The IACUC’s Wild Classification	1
ASO-mediated conversion of glial cells into neurons	1
It’s all about rhythm: how the circadian cycle modulates long-term immunity	1
Considering the non-specific effects of diphtheria toxin in cell-depletion studies	1

Watch and learn: role of hypothalamic neurons in mirroring aggression	1
Targeting the eicosanoid pathway treats COVID-19 in middle-aged mice	1
CRISPR gets crunchy	1
The weights of refinement and flexibility	1
Statistics, statistical thinking, and the IACUC	1
Rapid ammonia build-up in small individually ventilated mouse cages cannot be overcome by adjusting the amount of bedding	1
Don’t forget the bacteriophages	1
New insights into SARS-CoV-2 brain infection and olfactory impairment in the hamster model	1
A multi-omic resource of mouse neutrophils	1
Animal number versus maximum tumour volume: an example of reduction and refinement trade-off in the 3Rs	1
Opportunity for an improved animal care program	1
Genetically Modified Mishaps	1
Stress and feeding behavior in mice	1
A Word from USDA and OLAW	1
Earthquake!	1
Role of mitochondrial fission in stress susceptibility	1
Refinement of the stress-enhanced fear learning model of post-traumatic stress disorder: a behavioral and molecular analysis	1
AAV-induced toxicity in the brain	1
A systematic review of the impact of environmental enrichment in zebrafish	1
Generation of the NeoThy mouse model for human immune system studies	1
Reducing cage effects in mouse microbiome studies	1
Impact of microbiota on CNS macrophages	1
From data deluge to publomics: How AI can transform animal research	1
A new zebrafish model to study the link between TBI and dementia	1
You’ve Been Approved to Wait	1
Inheritance of directed DNA cytosine methylation in mammals	1
In This Issue	1
A genome-wide map of regulatory elements in zebrafish	1
Linking obesity, immune dysfunction and cancer risk	1
A bright fluorescent protein for neuronal imaging	1
MODs in need	1
Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA	1
FELASA2022 – Communication as a driver for better science, transparency, and animal welfare	1
Optimal conditions, experimentation and drug testing	1
Towards more translatable research: Exploring alternatives to gavage as the oral administration route of vaccines in rodents for improved animal welfare and human relevance	1
Fkbp5-humanized mice shed light on female higher vulnerability to stress	1
A Word from OLAW and USDA	1
Nonhuman primate models for SARS-CoV-2 research: Cryopreservation as a means to maintain critical models and enhance the genetic diversity of colonies	1
New insights into the APP family	1
The impact of COVID-19 lockdowns on the genetic integrity of your mouse colonies	1
Role of astroglial glutamine in memory	1
Share your zebrafish	1
Laboratory animals as potential biosensors to predict earthquakes	1
The well-built research question	1
Generation of a C57BL/6J mouse strain expressing the CD45.1 epitope to improve hematopoietic stem cell engraftment and adoptive cell transfer experiments	1
New insights into Rett syndrome	1
Assembly and operation of an easy-to-make portable device for facilitating mouse lateral tail-vein injection	1
An RFID-based tracking system gives mice their say	1
The Full Committee Review plunder	1
Machine learning identifies mitophagy inducers that ameliorate pathology in animal models of Alzheimer’s disease	1
3R centers tap into the human mindset to bolster replacement, reduction and refinement uptake	1
Monocytes regulate wound healing after infection via appetite hormones	1
Check the new Ratlas	0
Gut–lung axis in birds	0
Tracking lipid droplets in zebrafish	0
Brain origins in the octopus	0
Modularity for marmosets	0
Interactions in the sea urchin gut	0
Naked mole rats age epigenetically	0
Fish-derived organoids	0
A new “Periscope” to study the mouse cortex	0
In this issue	0
Delaying the Inevitable: a Justified Means to an End?	0
A Word from OLAW and USDA	0
Mapping gene expression in C.elegans neurons	0
Decreasing magnesium reverses the effects of Western Diet	0
Zebrafish shed light on regeneration research	0
Systemic taurine decline drives aging	0
A troubling designer drug	0
Neuronal areas behind play and laughter in rats	0
Health impact of different fats in rats	0
A more collegial process that facilitates compliance	0
Titan mice: a model for obesity research	0
Group size planning for breedings of gene-modified mice and other organisms following Mendelian inheritance	0
Alternate Rights	0
Male brains are more susceptible to high-fat diet	0
A mouse model of SARS-CoV-2 transmission	0
Compliance Considerations	0
Snakebites-on-a-chip	0
Understanding hybrid incompatibility in mice	0

A Word from OLAW and USDA	0
Phenotype screen identifies osteoporosis-related genes	0
Capturing liver responses to Plasmodium infection	0
In this issue	0
Breaking the barrier to treat Parkinson’s disease	0
A link between cell migration and DNA damage	0
Is a Suspension Without IACUC Vote a Suspension?	0
Buffering from Approval to Implementation	0
The gut-placenta axis	0
In This Issue	0
Ghrelin regulates pancreatic islet size in mice	0
ELVAs: The new ‘super-organelles’ of the oocyte	0
Role of striatum-projecting mPFC neurons in working memory	0
A new construct for CRISPR delivery in chicken	0
Long-term statins worsen diabetic nephropathy	0
Natural models in Oregon	0
Viral persistence in lungs	0
Shedding light on LAMP3	0
Two complementary neurotransmitters mediate decisions in monkeys	0
Mouse multi-organ proteome	0
Low-cost automated tool for 3D pose	0
A catalog of oligodendrocyte activation states in MS and AD	0
The Goal Should Not Be To Find Loopholes In Coverage	0
Orexin neurons regulate impulse behavior	0
Cancer resistance in bats	0
When Assigned but Now Unavailable	0
Individuality outweighs estrous cycle in affecting mouse behavior	0
Who is qualified to conduct the review?	0
Genetic considerations for sourcing research animals	0
Compliance Considerations	0
Octopus sleep phases are similar to mammals	0
In this issue	0
A Word from OLAW and USDA	0
A regulatory atlas of the fly brain	0
On the origins of red fish, blue fish	0
Hunger modulates aging in Drosophila	0
Do. Or Do Not. There is No Suspension	0
Light flicker boosts zebrafish visual recovery after injury	0
Sleep apnea during pregnancy affects brain development	0
Customer Inconvenience for Regulatory Convenience	0
Modeling coma	0
The Pain and Distress of VVC	0
A new mouse model to study the early-life microbiome	0
Bonding networks: fMRI reveals functional connectivity in prairie vole brains	0
Efficacy of mucosal vaccines in nonhuman primates	0
Astrocyte activation induces anxiolytic behavior in mice	0
Magic mushroom and zebrafish: A new recipe?	0
Developmental phenotyping goes on auto with LAMA	0
Pet and lab zebrafish microbes	0
Monitoring SARS-CoV-2 infection with reporter viruses	0
Alzheimer’s disease resilience might lie within the thalamic nucleus reuniens	0
Updates for axolotl	0
When is a House a Home?	0
A Word from OLAW	0
Neuronal vulnerability in social dysfunction	0
A C9orf72 LOF model in zebrafish	0
How sugar and cocaine affect the brain	0
A novel model of cardiovascular–kidney–metabolic syndrome combining unilateral nephrectomy and high-salt–sugar–fat diet in mice	0
Revisiting Reston virus	0
The Risk of Hazards, Hypothetically	0
Shared proteome in mice and humans with psychiatric disorders	0
Estrogen modulates cognitive function in mid-age female mice	0
Key role for oxytocin in emotional contagion	0
“Grey” areas of research in a Zoo setting	0
Renewed Responsibility	0
Once Used, Twice Counted	0
Cell therapy for type 1 diabetes in a nonhuman primate	0
Mapping neurons and cerebrovascular networks in mice	0
Transplanted human organoids for preclinical drug testing	0
Aggregated Mycobacterium tuberculosis exacerbate TB in rabbits	0
Impact of visual enrichment on group-housed zebrafish	0
Effects of volume management on free flap perfusion and metabolism in a large animal model study	0
Exercise improves polyQ disease in flies	0
A Sledgehammer To Crack a Nut?	0
Environmental enrichment improves mice motor performance	0
Distinct neurons control complex movements in Drosophila	0
A new lethal mouse-adapted SARS-CoV-2 for COVID research	0
Lifetime imaging of mouse brain vessels	0
Serotonin regulates sweet and bitter taste in Drosophila	0
New evidence linking serotonin and memory	0
Rewriting the mouse genome	0
In this issue	0
Speeding up screening in smaller zebrafish	0
New miniscope for large-scale in vivo calcium imaging	0
Open-source versatile 3D-print animal conditioning platform design for in vivo preclinical brain imaging in awake mice and anesthetized mice and rats	0
Measuring leukocyte trafficking in NHPs	0
Captive naked mole rats enjoy digging	0
Plan for Change	0
In this issue	0
Microglia gone wild	0
Insights into fungus–Drosophila interaction	0
The pig as an optimal animal model for cardiovascular research	0
Compliance Considerations	0
Enter the FlyBrainLab	0
Screening obesity genes in Drosophila	0