Cell

Article	Citations
Polyamine: A metabolic compass for T helper cell fate direction	9743
Autism-related dietary preferences mediate autism-gut microbiome associations	2598
A programmable reaction-diffusion system for spatiotemporal cell signaling circuit design	1611
A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion	1200
Bioactive metabolites: The double-edged sword in your food	1123
Reduction hits the sweet spot: A revised biosynthesis of dolichol	1031
Rings of death: How NINJ1 executes plasma membrane rupture	945
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy	907
Response to: The information theory of aging has not been tested	869
A microbial future	864
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center	841
Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice	821
Evolution and genetic adaptation of fishes to the deep sea	798
Microbial ecosystems and ecological driving forces in the deepest ocean sediments	766
Rational multienzyme architecture design with iMARS	761
MEER: Extraordinary flourishing ecosystem in the deepest ocean	745
Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization	743
Functional diversification of dietary plant small molecules by the gut microbiome	714
Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale	698
Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography	690
RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly	629
Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries	619
Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation	617
High fat intake sustains sorbitol intolerance after antibiotic-mediated Clostridia depletion from the gut microbiota	613
The chromosome folding problem and how cells solve it	609

Tracking self-performance in the prefrontal cortex: It’s layered	592
Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex	592
Transforming lives through genetics	578
Estrogen receptor gets a grip on RNA	539
CAR T therapy extends its reach to autoimmune diseases	535
Central-cell-produced attractants control fertilization recovery	518
Christine Guthrie (1945–2022)	518
Cell Line: 2014–2024	518
It’s the water! The open and shut case of drug-induced integrin activation	508
SnapShot: Mediator complex structure	493
Is genetic ancestry a tool to combat health disparities?	479
The power of parent scientists	464
The AD odyssey 2023: Tales of single cell	459
Et tu, Vibrio cholerae? Kin-cannibalism and a bacterial secretion system	456
Roll out the barrel! Outer membrane tension resolves an unexpected folding intermediate	452
Unlocking the single-cell mysteries of a reef-building coral	445
Awakening: Losing then finding myself in STEMM	428
Persistent progress	425
Generating and using real-world data: A worthwhile uphill battle	421
Immunology is for everyone	413
A call from patient-researchers to advance research on long COVID	397
Assessing gender disparity among Cell authors	393
The brain remembers where and how inflammation struck	392
When boundaries benefit science and society	389
How to build a crop plant: Defining the cis-regulatory landscape of maize	388
Creating collaboration by breaking down scientific barriers	388
Recycling of modified H2A-H2B provides short-term memory of chromatin states	369
The neuroscience of mental illness: Building toward the future	367
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever	363
Regulation of human interferon signaling by transposon exonization	362
Biosensors based on peptide exposure show single molecule conformations in live cells	361
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex	358
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite	357
The innovation menagerie: New institutional structures are expanding horizons for early-stage research	353
Bridging worlds: A STEM journey from Nigeria to the US and back	353
The next decade of protein structure	352
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity	347
Underrepresentation of Asian awardees of United States biomedical research prizes	346
Keiji Tanaka (1949–2024)	340
Enough with “the shakes”: Fighting Parkinson’s as a Black researcher and a community organizer	337
A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression	336
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision	334
Choroid plexus mast cells drive tumor-associated hydrocephalus	334
Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake	332
Evolutionary assembly of cooperating cell types in an animal chemical defense system	332
DNA-based ForceChrono probes for deciphering single-molecule force dynamics in living cells	332
Spin glasses, error correcting codes, and synchronization of human stem cell organoids	328
The cost of competency?	326
The coyote in the mirror: Embracing intersectionality to improve human-wildlife interactions	324
Science bridges political barriers	323

Enhancing translation of science into non-English languages	321
What does Juneteenth mean in STEMM?	320
A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation	318
Prying the lid open: Atomic-level insights on sialoglycan-TMPRSS2 coordination in HKU1 entry	318
Patterning by contraction	317
Using virtual interviewing to create a more accessible hybrid academic job market	313
Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide	313
Getting to the heart of cannabis health risks	310
TIR domains as two-tiered enzymes to activate plant immunity	310
Centromeres organize (epi)genome architecture	308
De novo deletions and duplications at recombination hotspots in mouse germlines	307
Quorum-sensing- and type VI secretion-mediated spatiotemporal cell death drives genetic diversity in Vibrio cholerae	306
By their powers combined, global initiative joins forces for genomic research	297
Magnetic soft robotics to manipulate the extracellular matrix in vitro	291
Controlling the crowd with a WNK	291
Mechanobiology: How pathogens use mechanics to modulate host interactions	290
EBV and MS: The evidence is growing stronger	289
Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus	288
Cryo-EM-based discovery of a pathogenic parvovirus causing epidemic mortality by black wasting disease in farmed beetles	286
Founder cells shape brain evolution	284
Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair	282
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope	280
A PICture is worth a thousand words (and ten references)	279
Memory B cell fitness and anergy has significant links to cancer lethality	277
Unveiling of a messenger: Gut microbes make a neuroactive signal	276
Automated profiling of gene function during embryonic development	272
Africa in the era of pathogen genomics: Unlocking data barriers	271
Structural insights into the diversity and DNA cleavage mechanism of Fanzor	270
Lung-resident alveolar macrophages regulate the timing of breast cancer metastasis	270
Laws of thought in living cells	270
Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens	270
Private information leakage from single-cell count matrices	265
Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8	263
Through the looking glass: An adventure into the metastable world of the bacterial cytoplasm	260
The need to diversify genomic studies: Insights from Andean highlanders and Amazonians	257
The power of storytelling in STEM	254
Wave-like dopamine dynamics as a mechanism for spatiotemporal credit assignment	251
Extremely potent human monoclonal antibodies from COVID-19 convalescent patients	251
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies	250
The expanding world of neuroscience	250
Future views on neuroscience and AI	248
Convergent evolution in the supercoiling of prokaryotic flagellar filaments	247
Muscle fusogens go viral for gene delivery to skeletal muscle	247
Self-demixing of mRNA copies buffers mRNA:mRNA and mRNA:regulator stoichiometries	247
Learning from HBCUs: How to produce Black professionals in STEMM	247
Continuous germinal center invasion contributes to the diversity of the immune response	244
Insular cortex neurons encode and retrieve specific immune responses	241
A metabolic balance of GLP-1 and NMDA receptors in the brain	239
From periphery to center stage: 50 years of advancements in innate immunity	238
Optical Mapping of cAMP Signaling at the Nanometer Scale	237
SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53	235
Hypothalamic neurons that mirror aggression	234
Closing the scissor-shaped curve: Strategies to promote gender equality in academia	233
Judith Campisi (1948–2024)	231
A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation	230
Design of CoQ10 crops based on evolutionary history	230
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease	229
Microbial transformation of dietary xenobiotics shapes gut microbiome composition	229
Interdisciplinary approaches are fundamental to decode the biology of adversity	229
Parallel neural pathways control sodium consumption and taste valence	227
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival	226
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system	224
Structures of LRP2 reveal a molecular machine for endocytosis	222
SON-light activation of glucose regulation	222
Inflammatory adaptation in barrier tissues	222
Spatially confined sub-tumor microenvironments in pancreatic cancer	222
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation	221
Parental genome unification is highly error-prone in mammalian embryos	219
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape	218
Structural analysis of the full-length human LRRK2	215
Mechanoreceptor synapses in the brainstem shape the central representation of touch	214
Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders	214
Mapping transcriptomic vector fields of single cells	214
Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice	214
A disordered region controls cBAF activity via condensation and partner recruitment	213
Identification, structure, and agonist design of an androgen membrane receptor	213
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome	212
Bound by the love for cholesterol: A transporter meets a GPCR	211
Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome	210
A deep learning strategy to identify cell types across species from high-density extracellular recordings	209

Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus	209
Patterning and folding of intestinal villi by active mesenchymal dewetting	206
Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample	206
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin	204
Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony	204
ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat	203
Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas	202
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells	201
Capturing totipotency in human cells through spliceosomal repression	201
In vitro human cell-based models: What can they do and what are their limitations?	200
Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies	199
Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung	198
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas	198
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations	197
Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity	197
Synthetic mammalian signaling circuits for robust cell population control	196
Clonal replacement sustains long-lived germinal centers primed by respiratory viruses	195
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology	195
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility	195
Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation	195
Innovation, conservation, and repurposing of gene function in root cell type development	194
Structural basis of membrane skeleton organization in red blood cells	194
Fluorescence imaging of large-scale neural ensemble dynamics	193
Representational geometry of perceptual decisions in the monkey parietal cortex	193
Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis	192
The proteomic landscape of genome-wide genetic perturbations	192
Direct visualization of electric-field-stimulated ion conduction in a potassium channel	191
Functional partitioning of transcriptional regulators by patterned charge blocks	191
In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-ET	190
Brain-body physiology: Local, reflex, and central communication	188
Ovarian cancer-derived IL-4 promotes immunotherapy resistance	186
An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes	185
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry	184
Embryonic origins of adult pluripotent stem cells	184
Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth	183
Lineage-specific 3D genome organization is assembled at multiple scales by IKAROS	183
Global organelle profiling reveals subcellular localization and remodeling at proteome scale	183
Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses	181
Generating parallel representations of position and identity in the olfactory system	181
Cancer immunotherapy: T cells and neutrophils working together to attack cancers	179
The ribosome comes to life	178
OLAH connects fatty acid metabolism to the severity of respiratory viral disease	178
Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes	178
Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals	176
Bacterial NLR-related proteins protect against phage	175
RNA promotes the formation of spatial compartments in the nucleus	174
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution	171
Reply to Over-celling fetal microbial exposure	171
Impaired neural replay of inferred relationships in schizophrenia	171
Functional diversity for body actions in the mesencephalic locomotor region	170
A developmental constraint model of cancer cell states and tumor heterogeneity	168
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex	166
Mining human microbiomes reveals an untapped source of peptide antibiotics	166
Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes	166
XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells	166
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies	165
Systemic immune profiling of Omicron-infected subjects inoculated with different doses of inactivated virus vaccine	165
A thalamic-primary auditory cortex circuit mediates resilience to stress	165
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling	163
Structure-based discovery of CFTR potentiators and inhibitors	163
The deep population history of northern East Asia from the Late Pleistocene to the Holocene	162
Type-I-interferon-responsive microglia shape cortical development and behavior	162
Menopause—Biology, consequences, supportive care, and therapeutic options	161
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells	161
Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels	161
PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development	160
RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation	160
Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition	159
In vivo DNA replication dynamics unveil aging-dependent replication stress	158
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread	157
Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants	156
Vision-dependent specification of cell types and function in the developing cortex	156
Population immunity predicts evolutionary trajectories of SARS-CoV-2	155
SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms	154
Genomic architecture of autism from comprehensive whole-genome sequence annotation	154
Circular RNAs: Characterization, cellular roles, and applications	154
SnapShot: Eukaryotic ribosome biogenesis II	154
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity	153
TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons	152
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes	152
An early cell shape transition drives evolutionary expansion of the human forebrain	152
Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5	151
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation	151
Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine	150
Cell death	150
Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states	149
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations	148
Neutrophil profiling illuminates anti-tumor antigen-presenting potency	148
An in vitro system to silence mitochondrial gene expression	148
A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation	148
Short-distance vesicle transport via phase separation	147
Scientists’ call to action: Microbes, planetary health, and the Sustainable Development Goals	147
Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic	147
Brain-wide representations of behavior spanning multiple timescales and states in C. elegans	146
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs	145