Cell

Article	Citations
Learning from HBCUs: How to produce Black professionals in STEMM	10084
How to build a crop plant: Defining the cis-regulatory landscape of maize	2764
A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation	1697
Response to: The information theory of aging has not been tested	1241
A metabolic balance of GLP-1 and NMDA receptors in the brain	1059
From periphery to center stage: 50 years of advancements in innate immunity	969
Muscle fusogens go viral for gene delivery to skeletal muscle	876
Prying the lid open: Atomic-level insights on sialoglycan-TMPRSS2 coordination in HKU1 entry	848
Evolution and genetic adaptation of fishes to the deep sea	814
The expanding world of neuroscience	796
Patterning by contraction	787
Keiji Tanaka (1949–2024)	769
Reply to Over-celling fetal microbial exposure	766
Channel synapse mediates neurotransmission of airway protective chemoreflexes	724
Five decades of advances in cancer research	712
Global surveillance and countermeasures for ACE2-using MERS-related coronaviruses with spillover risk	708
In vivo DNA replication dynamics unveil aging-dependent replication stress	646
Evolutionary assembly of cooperating cell types in an animal chemical defense system	644
Structure-based discovery of CFTR potentiators and inhibitors	636
Choroid plexus mast cells drive tumor-associated hydrocephalus	622
Structure and infection dynamics of mycobacteriophage Bxb1	619
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin	604
A deep learning strategy to identify cell types across species from high-density extracellular recordings	559
Ovarian cancer-derived IL-4 promotes immunotherapy resistance	556
Genomic architecture of autism from comprehensive whole-genome sequence annotation	554

Recycling of modified H2A-H2B provides short-term memory of chromatin states	533
Structural basis for Cas9 off-target activity	529
Structures of LRP2 reveal a molecular machine for endocytosis	519
EBV and MS: The evidence is growing stronger	513
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity	482
Biosensors based on peptide exposure show single molecule conformations in live cells	481
In vitro human cell-based models: What can they do and what are their limitations?	469
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite	462
Functional diversification of dietary plant small molecules by the gut microbiome	449
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells	435
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas	432
Synthetic mammalian signaling circuits for robust cell population control	426
Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic	413
OLAH connects fatty acid metabolism to the severity of respiratory viral disease	405
Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants	403
Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias	400
Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses	399
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells	393
Local hyperthermia therapy induces browning of white fat and treats obesity	386
SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms	385
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations	384
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution	380
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility	373
A pan-cancer analysis of the microbiome in metastatic cancer	367
Bound by the love for cholesterol: A transporter meets a GPCR	366
PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development	366
RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly	366
CAR T therapy extends its reach to autoimmune diseases	362
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome	362
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center	356
Deciphering breast cancer: from biology to the clinic	352
Structural specializations of the sperm tail	351
Macrophages at the interface of the co-evolving cancer ecosystem	343
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma	342
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex	341
Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation	339
Cardioids reveal self-organizing principles of human cardiogenesis	336
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs	334
Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease	334
A gut-retching discovery	334
Propofol: Milk of Amnesia	331
Structurally divergent and recurrently mutated regions of primate genomes	331
Structural basis of respiratory complex adaptation to cold temperatures	330
Unrealized potential from smaller institutions: Four strategies for advancing STEM diversity	328
The developmental basis of fingerprint pattern formation and variation	327
Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine	327
Multi-layered computational gene networks by engineered tristate logics	322
SnapShot: Condensates in plant biology	322
Building and supporting identity in peer review	317
To see is to experience: Aggression neurons light up when witnessing a fight	314

Fungal sugars boost vaccine protection	313
Cell surface fluctuations regulate early embryonic lineage sorting	303
Pursuing structural biology in China	300
The information theory of aging has not been tested	298
How do DEI initiatives impact STEMM, and why do we still need them?	296
It took a long, long time: Ras and the race to cure cancer	295
Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding	294
Engineering RNA export for measurement and manipulation of living cells	293
Co-opting templated aggregation to degrade pathogenic tau assemblies and improve motor function	290
Mechanism of IFT-A polymerization into trains for ciliary transport	289
Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration	284
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs	281
Nutrition, longevity and disease: From molecular mechanisms to interventions	275
A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement	274
Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition	274
Influence of autozygosity on common disease risk across the phenotypic spectrum	270
Gut-liver axis calibrates intestinal stem cell fitness	268
Spatial CRISPR genomics identifies regulators of the tumor microenvironment	267
Sleep is required to consolidate odor memory and remodel olfactory synapses	267
An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms	267
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity	267
Infodemics: A new challenge for public health	264
A genetic basis for sex differences in Xp11 translocation renal cell carcinoma	262
Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic	261
The interferon landscape along the respiratory tract impacts the severity of COVID-19	256
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients	256
Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss	256
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification	254
Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy	251
HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity	248
Microglia maintain structural integrity during fetal brain morphogenesis	248
Precision medicine requires understanding how both sex and gender influence health	247
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals	244
TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity	241
The first two blastomeres contribute unequally to the human embryo	239
Central nervous system regeneration	238
Hallmarks of neurodegenerative diseases	237
Parallel and distributed encoding of speech across human auditory cortex	237
A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior	236
Freedom of expression: A synthetic route to metabolites	236
An Arabidopsis single-nucleus atlas decodes leaf senescence and nutrient allocation	235
Before and after farming: The genetic structure of South China and Southeast Asia	235
Evolution of diapause in the African turquoise killifish by remodeling the ancient gene regulatory landscape	231
Pathogen protein modularity enables elaborate mimicry of a host phosphatase	231
Novel integrative elements and genomic plasticity in ocean ecosystems	230
Fine particle air pollution and lung cancer risk: Extending the long list of health risks	229
Ultrafast distant wound response is essential for whole-body regeneration	228
Root microbiota regulates tiller number in rice	226
Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes	225
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease	224
Gut microbiome ecological topology as next-generation biomarkers for cancer immunotherapy	224
From microbial membrane proteins to the mysteries of emotion	224
Intracellular calcium release: A conductor of compartmentalized dendritic plasticity	222
Immune checkpoint blockade provokes resident memory T cells to eliminate head and neck cancer	221
Digital phenotyping from wearables using AI characterizes psychiatric disorders and identifies genetic associations	220
Small-molecule hypoxia therapy in mitochondrial disease	220
Celebrating our origins with cell biology	219
Virome characterization of game animals in China reveals a spectrum of emerging pathogens	218
A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells	217
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution	217
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes	216
Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily	216
Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer	216
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality	214
TGF-β signaling in health and disease	213
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies	211
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin	210
Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network	209
SnapShot: Cell size control	208
Tracing the origin of alveolar stem cells in lung repair and regeneration	206
Open-ST: High-resolution spatial transcriptomics in 3D	203
Engineered cell entry links receptor biology with single-cell genomics	203
Mining metatranscriptomes reveals a vast world of viroid-like circular RNAs	202
An NK-like CAR T cell transition in CAR T cell dysfunction	202
Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs	202
A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation	201
Multimodal charting of molecular and functional cell states via in situ electro-sequencing	201
PIEZO2 in somatosensory neurons controls gastrointestinal transit	200
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation	200
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays	199

Small STEPs toward a big change	198
Induced epigenetic changes memorized across generations in mice	195
ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors	194
Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT	193
Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution	192
Exploring RNA-guided DNA scissors in eukaryotes: Are Fanzors counterparts of CRISPR-Cas12s?	192
Sensational channels	188
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques	188
Paul Berg and the origins of recombinant DNA	188
Mechanism of DNA capture by the MukBEF SMC complex and its inhibition by a viral DNA mimic	187
Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome	187
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic	186
A general chemical principle for creating closure-stabilizing integrin inhibitors	185
The genetic history of Scandinavia from the Roman Iron Age to the present	185
High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients	182
Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin	181
Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance	180
A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance	179
Nothing about us without us: Sharing results with communities that provide genomic data	179
Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion	178
Overcoming drug resistance in cancer	177
A multi-tissue metabolome atlas of primate pregnancy	176
Designing antibodies as therapeutics	176
Emergence of an early SARS-CoV-2 epidemic in the United States	175
Comparative landscape of genetic dependencies in human and chimpanzee stem cells	174
Atlas of the aging mouse brain reveals white matter as vulnerable foci	171
Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates	170
Bispecific dendritic-T cell engager potentiates anti-tumor immunity	170
A neutrophil response linked to tumor control in immunotherapy	169
ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion	168
How to build the virtual cell with artificial intelligence: Priorities and opportunities	168
Human microglial state dynamics in Alzheimer’s disease progression	166
Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation	166
Cancer neuroscience: State of the field, emerging directions	166
Hippocampal neurons construct a map of an abstract value space	166
Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture	164
Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate	164
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway	163
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling	163
The extracellular matrix integrates mitochondrial homeostasis	163
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant	162
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins	161
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions	161
Proteome-scale movements and compartment connectivity during the eukaryotic cell cycle	160
Snapshot: Choroid plexus brain barrier	160
Spatial proteomics in neurons at single-protein resolution	160
Charting human development using a multi-endodermal organ atlas and organoid models	159
Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors	158
Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels	158
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases	157
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans	157
ER stress transforms random olfactory receptor choice into axon targeting precision	155
GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA	155
Chromosome-level organization of the regulatory genome in the Drosophila nervous system	155
Endometriosis: Etiology, pathobiology, and therapeutic prospects	155
Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants	154
A widely distributed gene cluster compensates for uricase loss in hominids	154
Resmetirom for treatment of MASH	153
Phage therapy: From biological mechanisms to future directions	152
Macrophages in health and disease	151
Jumbo phage killer immune system targets early infection of nucleus-forming phages	150
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity	150
Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes	150
A conserved family of immune effectors cleaves cellular ATP upon viral infection	150
Emergency drug use in a pandemic: Harsh lessons from COVID-19	149
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment	149
Lrp1 is a host entry factor for Rift Valley fever virus	149
First come, first served: Mammalian recombination is timed to replication	148
Fe, fi, fo, fum, I smell the diet of a healthy human	147
Before you call the midwife	147
Seven days in the life cycle of Homo sapiens	147
Harnessing social media to challenge scientific misinformation	146
Medication effects on the gut microbiome in allo-HCT	146
Structural studies put phage defense mystery on the RADAR	146
Staphylococcus scratches its itch	145
Learning lessons from lipids to make COVID-19 vaccines	145
Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants	144
Modularity and robustness of frontal cortical networks	143
Opposing GPCR signaling programs protein intake setpoint in Drosophila	143
Cervicovaginal microbiome and natural history of Chlamydia trachomatis in adolescents and young women	143
Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress	143
Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes	142
Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli	142
Problem choice and decision trees in science and engineering	141
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response	141
Microbial colonization programs are structured by breastfeeding and guide healthy respiratory development	141
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development	140
Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer	140
Toward a foundation model of causal cell and tissue biology with a Perturbation Cell and Tissue Atlas	140
Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer	139
Saturation mutagenesis-reinforced functional assays for disease-related genes	138
Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations	137
SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2	136
Transport mechanism and pharmacology of the human GlyT1	136
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire	136