Cell

Article	Citations
Polyamine: A metabolic compass for T helper cell fate direction	8642
Getting to the heart of cannabis health risks	2075
Closing the scissor-shaped curve: Strategies to promote gender equality in academia	1452
Using artificial intelligence to document the hidden RNA virosphere	1336
RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation	1096
Through the looking glass: An adventure into the metastable world of the bacterial cytoplasm	1072
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread	924
Autism-related dietary preferences mediate autism-gut microbiome associations	904
A programmable reaction-diffusion system for spatiotemporal cell signaling circuit design	849
Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus	848
Rings of death: How NINJ1 executes plasma membrane rupture	819
Cell Line: 2014–2024	800
A gut commensal protozoan determines respiratory disease outcomes by shaping pulmonary immunity	793
Rational multienzyme architecture design with iMARS	754
Direct visualization of electric-field-stimulated ion conduction in a potassium channel	753
Bioactive metabolites: The double-edged sword in your food	727
Reduction hits the sweet spot: A revised biosynthesis of dolichol	678
Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography	670
A microbial future	668
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center	618
Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice	612
Parental genome unification is highly error-prone in mammalian embryos	600
Proteogenomic characterization of pancreatic ductal adenocarcinoma	598
Inflammatory adaptation in barrier tissues	583
Founder cells shape brain evolution	569

DNA-based ForceChrono probes for deciphering single-molecule force dynamics in living cells	560
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility	551
Structure-based discovery of CFTR potentiators and inhibitors	537
Tracking self-performance in the prefrontal cortex: It’s layered	525
Transforming lives through genetics	518
A PICture is worth a thousand words (and ten references)	517
Estrogen receptor gets a grip on RNA	511
SnapShot: Mediator complex structure	508
Patterning by contraction	504
By their powers combined, global initiative joins forces for genomic research	500
Is genetic ancestry a tool to combat health disparities?	462
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation	459
Scientific misinformation: A perfect storm, missteps, and moving forward	455
Judith Campisi (1948–2024)	444
De novo deletions and duplications at recombination hotspots in mouse germlines	443
Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses	433
CAR T therapy extends its reach to autoimmune diseases	428
Patterning and folding of intestinal villi by active mesenchymal dewetting	426
A neuropeptide making memories	416
Central-cell-produced attractants control fertilization recovery	416
The power of parent scientists	414
Quorum-sensing- and type VI secretion-mediated spatiotemporal cell death drives genetic diversity in Vibrio cholerae	406
Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5	404
EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion	396
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry	393
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis	385
The AD odyssey 2023: Tales of single cell	383
Unlocking the single-cell mysteries of a reef-building coral	373
Reply to Over-celling fetal microbial exposure	355
Awakening: Losing then finding myself in STEMM	355
Persistent progress	345
Controlling the crowd with a WNK	344
Using virtual interviewing to create a more accessible hybrid academic job market	344
Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8	339
Generating and using real-world data: A worthwhile uphill battle	338
Immunology is for everyone	329
A glycolytic metabolite bypasses “two-hit” tumor suppression by BRCA2	327
Time-series reconstruction of the molecular architecture of human centriole assembly	326
Deep discovery informs difficult deployment in plant microbiome science	324
Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony	324
Five decades of advances in cancer research	324
RNA damage compartmentalization by DHX9 stress granules	323
Recycling of modified H2A-H2B provides short-term memory of chromatin states	320
Brain-body physiology: Local, reflex, and central communication	319
Memory B cell fitness and anergy has significant links to cancer lethality	317
A call from patient-researchers to advance research on long COVID	314
Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake	314
The modified RNA base acp3U is an attachment site for N-glycans in glycoRNA	311
Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels	309
Flying under the radar: TMEM106B(120–254) fibrils break out in diverse neurodegenerative disorders	303

Assessing gender disparity among Cell authors	301
High fat intake sustains sorbitol intolerance after antibiotic-mediated Clostridia depletion from the gut microbiota	301
A replication fork determinant for the establishment of sister chromatid cohesion	293
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever	291
The brain remembers where and how inflammation struck	285
Mechanoreceptor synapses in the brainstem shape the central representation of touch	282
When boundaries benefit science and society	282
How to build a crop plant: Defining the cis-regulatory landscape of maize	280
Centromeres organize (epi)genome architecture	280
Creating collaboration by breaking down scientific barriers	279
Christine Guthrie (1945–2022)	278
It’s the water! The open and shut case of drug-induced integrin activation	278
TIR domains as two-tiered enzymes to activate plant immunity	277
A cis-regulatory atlas in maize at single-cell resolution	277
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape	275
Et tu, Vibrio cholerae? Kin-cannibalism and a bacterial secretion system	269
Roll out the barrel! Outer membrane tension resolves an unexpected folding intermediate	265
Response to: The information theory of aging has not been tested	263
The next decade of protein structure	262
Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice	260
“Iron”ing out hemophagocytosis through PIEZO1	258
Underrepresentation of Asian awardees of United States biomedical research prizes	258
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity	258
Interdisciplinary approaches are fundamental to decode the biology of adversity	257
Keiji Tanaka (1949–2024)	257
A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression	256
Enough with “the shakes”: Fighting Parkinson’s as a Black researcher and a community organizer	256
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion	255
Choroid plexus mast cells drive tumor-associated hydrocephalus	254
EBV and MS: The evidence is growing stronger	253
Parallel neural pathways control sodium consumption and taste valence	252
Regulation of human interferon signaling by transposon exonization	249
Ovarian cancer-derived IL-4 promotes immunotherapy resistance	248
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision	248
A plant immune protein enables broad antitumor response by rescuing microRNA deficiency	240
Circular RNAs: Characterization, cellular roles, and applications	240
Mapping transcriptomic vector fields of single cells	238
Integrated analysis of multimodal single-cell data	236
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity	234
Circular RNA vaccines against SARS-CoV-2 and emerging variants	233
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations	232
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies	229
Mouse totipotent stem cells captured and maintained through spliceosomal repression	229
Massive expansion of human gut bacteriophage diversity	227
Changes in genome architecture and transcriptional dynamics progress independently of sensory experience during post-natal brain development	225
OLAH connects fatty acid metabolism to the severity of respiratory viral disease	224
ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat	224
Spin glasses, error correcting codes, and synchronization of human stem cell organoids	222
The cost of competency?	222
The coyote in the mirror: Embracing intersectionality to improve human-wildlife interactions	220
Enhancing translation of science into non-English languages	219
Science bridges political barriers	219
Unveiling of a messenger: Gut microbes make a neuroactive signal	217
Automated profiling of gene function during embryonic development	217
Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus	217
What does Juneteenth mean in STEMM?	217
RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly	215
Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation	215
Prying the lid open: Atomic-level insights on sialoglycan-TMPRSS2 coordination in HKU1 entry	215
A tissue injury sensing and repair pathway distinct from host pathogen defense	213
Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide	213
A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation	212
Capturing totipotency in human cells through spliceosomal repression	211
Functional diversity for body actions in the mesencephalic locomotor region	211
Dynamic mapping of proteome trafficking within and between living cells by TransitID	210
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine	209
Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung	208
Menopause—Biology, consequences, supportive care, and therapeutic options	208
Biosensors based on peptide exposure show single molecule conformations in live cells	208
Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex	207
An in vitro system to silence mitochondrial gene expression	202
Training the metaorganism: the microbial counterpart	202
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite	202
Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis	201
In vitro human cell-based models: What can they do and what are their limitations?	201
In vivo DNA replication dynamics unveil aging-dependent replication stress	196
Scientists’ call to action: Microbes, planetary health, and the Sustainable Development Goals	195
Microbial transformation of dietary xenobiotics shapes gut microbiome composition	195
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival	194
Cryo-EM-based discovery of a pathogenic parvovirus causing epidemic mortality by black wasting disease in farmed beetles	194

Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens	194
The neuroscience of mental illness: Building toward the future	193
Decoding the brain: From neural representations to mechanistic models	191
Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy	191
Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic	190
Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome	190
Magnetic soft robotics to manipulate the extracellular matrix in vitro	189
Divergent sensory pathways of sneezing and coughing	188
The need to diversify genomic studies: Insights from Andean highlanders and Amazonians	188
Africa in the era of pathogen genomics: Unlocking data barriers	188
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease	187
The power of storytelling in STEM	185
Laws of thought in living cells	185
Mechanobiology: How pathogens use mechanics to modulate host interactions	183
TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons	182
SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms	182
An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes	182
MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels	181
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies	181
TERT activation targets DNA methylation and multiple aging hallmarks	181
The expanding world of neuroscience	181
Future views on neuroscience and AI	180
Type-I-interferon-responsive microglia shape cortical development and behavior	179
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation	178
Systemic immune profiling of Omicron-infected subjects inoculated with different doses of inactivated virus vaccine	178
Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair	178
Structures of the entire human opioid receptor family	177
Establishing a conceptual framework for holistic cell states and state transitions	177
Representational geometry of perceptual decisions in the monkey parietal cortex	177
XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells	176
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion	176
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations	175
The long-term genetic stability and individual specificity of the human gut microbiome	175
Fluorescence imaging of large-scale neural ensemble dynamics	174
Neural mechanism underlying depressive-like state associated with social status loss	173
RNA aggregates harness the danger response for potent cancer immunotherapy	173
Cell death	173
Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas	172
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin	171
Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis	170
Mining human microbiomes reveals an untapped source of peptide antibiotics	169
A pan-cancer analysis of the microbiome in metastatic cancer	169
The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins	169
Embryonic origins of adult pluripotent stem cells	168
Allogeneic CD19-targeted CAR-T therapy in patients with severe myositis and systemic sclerosis	168
Clonal replacement sustains long-lived germinal centers primed by respiratory viruses	166
Influences of rare copy-number variation on human complex traits	165
Structural basis for Cas9 off-target activity	165
Multiphase coalescence mediates Hippo pathway activation	164
What is a cell type and how to define it?	163
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex	162
Macrophages at the interface of the co-evolving cancer ecosystem	162
Pancreatic cancer: Advances and challenges	161
A disordered region controls cBAF activity via condensation and partner recruitment	161
T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants	161
Bacterial NLR-related proteins protect against phage	160
Circadian clocks are modulated by compartmentalized oscillating translation	159
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma	158
Structural specializations of the sperm tail	158
Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition	157
The innovation menagerie: New institutional structures are expanding horizons for early-stage research	157
Magnesium sensing via LFA-1 regulates CD8+ T cell effector function	156
Global organelle profiling reveals subcellular localization and remodeling at proteome scale	156
Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis	154
De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking	154
Neutrophil profiling illuminates anti-tumor antigen-presenting potency	153
Snapshot of the cannabinoid receptor 1-arrestin complex unravels the biased signaling mechanism	153
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope	152
Cancer immunotherapy: T cells and neutrophils working together to attack cancers	151
Muscle fusogens go viral for gene delivery to skeletal muscle	149
Synthetic mammalian signaling circuits for robust cell population control	149
Vision-dependent specification of cell types and function in the developing cortex	149
A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation	149
Brain-wide representations of behavior spanning multiple timescales and states in C. elegans	148
Strength in numbers: predicting response to checkpoint inhibitors from large clinical datasets	147
Generating parallel representations of position and identity in the olfactory system	146
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome	146
A thalamic-primary auditory cortex circuit mediates resilience to stress	144
Immune cell interactions in tuberculosis	144
Structures of LRP2 reveal a molecular machine for endocytosis	144
Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale	144
A developmental constraint model of cancer cell states and tumor heterogeneity	143
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex	143
Learning from HBCUs: How to produce Black professionals in STEMM	142
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis	141
SnapShot: Eukaryotic ribosome biogenesis II	141
Incomplete lineage sorting and phenotypic evolution in marsupials	141
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells	141
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology	140
Cardioids reveal self-organizing principles of human cardiogenesis	140
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions	140
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution	140
From rare disorders of immunity to common determinants of infection: Following the mechanistic thread	140
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling	139
Local hyperthermia therapy induces browning of white fat and treats obesity	139