Cell

Article	Citations
Keiji Tanaka (1949–2024)	4153
Muscle fusogens go viral for gene delivery to skeletal muscle	2232
A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation	1262
Learning from HBCUs: How to produce Black professionals in STEMM	1208
CAR T therapy extends its reach to autoimmune diseases	920
In vitro human cell-based models: What can they do and what are their limitations?	907
Patterning by contraction	892
Mesoscopic mapping of the brain: From rodents to primates	883
Shaping pit structure in vessel walls sustains xylem hydraulics and grain yield	856
Prying the lid open: Atomic-level insights on sialoglycan-TMPRSS2 coordination in HKU1 entry	822
A metabolic balance of GLP-1 and NMDA receptors in the brain	799
Evolutionary assembly of cooperating cell types in an animal chemical defense system	798
From periphery to center stage: 50 years of advancements in innate immunity	767
Bound by the love for cholesterol: A transporter meets a GPCR	751
Recycling of modified H2A-H2B provides short-term memory of chromatin states	734
Structure and infection dynamics of mycobacteriophage Bxb1	727
Synthetic mammalian signaling circuits for robust cell population control	726
Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses	723
A deep learning strategy to identify cell types across species from high-density extracellular recordings	670
OLAH connects fatty acid metabolism to the severity of respiratory viral disease	610
Response to: The information theory of aging has not been tested	596
De novo assembly of nuclear stress bodies rearranges and enhances NFIL3 to restrain acute inflammatory responses	570
Five decades of advances in cancer research	569
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center	562
Global surveillance and countermeasures for ACE2-using MERS-related coronaviruses with spillover risk	520

Procr+ chondroprogenitors sense mechanical stimuli to govern articular cartilage maintenance and regeneration	514
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome	502
Genomic architecture of autism from comprehensive whole-genome sequence annotation	498
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite	489
Channel synapse mediates neurotransmission of airway protective chemoreflexes	487
Structures of LRP2 reveal a molecular machine for endocytosis	485
Interferons in health and disease	483
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin	481
Structure-based discovery of CFTR potentiators and inhibitors	481
Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants	474
Local hyperthermia therapy induces browning of white fat and treats obesity	466
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells	464
EBV and MS: The evidence is growing stronger	462
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma	451
Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias	448
RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly	437
PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development	429
Structural basis for Cas9 off-target activity	429
Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic	422
Evolution and genetic adaptation of fishes to the deep sea	418
Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation	409
Structural specializations of the sperm tail	401
Senescence-resistant human mesenchymal progenitor cells counter aging in primates	401
Functional diversification of dietary plant small molecules by the gut microbiome	398
Choroid plexus mast cells drive tumor-associated hydrocephalus	388
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution	387
Macrophages at the interface of the co-evolving cancer ecosystem	371
Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain	363
A pan-cancer analysis of the microbiome in metastatic cancer	362
In vivo DNA replication dynamics unveil aging-dependent replication stress	354
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility	353
Ovarian cancer-derived IL-4 promotes immunotherapy resistance	347
Deciphering breast cancer: from biology to the clinic	340
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex	334
The expanding world of neuroscience	325
Pursuing structural biology in China	324
Mechanism of IFT-A polymerization into trains for ciliary transport	318
A genetic basis for sex differences in Xp11 translocation renal cell carcinoma	318
HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity	318
Fungal sugars boost vaccine protection	315
To see is to experience: Aggression neurons light up when witnessing a fight	314
A gut-retching discovery	310
Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition	307
How do DEI initiatives impact STEMM, and why do we still need them?	307
Precision medicine requires understanding how both sex and gender influence health	305
Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1	303
The information theory of aging has not been tested	296
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs	294
A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis	294
A mechano-resistance mechanism in skin adapts to terrestrial locomotion	289

Cell surface fluctuations regulate early embryonic lineage sorting	287
Structural basis of respiratory complex adaptation to cold temperatures	286
Ancient hybridization underlies tuberization and radiation of the potato lineage	284
Gut-liver axis calibrates intestinal stem cell fitness	282
It took a long, long time: Ras and the race to cure cancer	281
Multi-layered computational gene networks by engineered tristate logics	278
A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior	277
Influence of autozygosity on common disease risk across the phenotypic spectrum	277
An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms	276
SnapShot: Condensates in plant biology	275
Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration	274
Structurally divergent and recurrently mutated regions of primate genomes	273
Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease	272
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity	271
Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding	269
Engineering RNA export for measurement and manipulation of living cells	264
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification	264
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients	262
Propofol: Milk of Amnesia	260
Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine	259
Infodemics: A new challenge for public health	258
Microglia maintain structural integrity during fetal brain morphogenesis	258
A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement	257
Co-opting templated aggregation to degrade pathogenic tau assemblies and improve motor function	250
Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss	249
The first two blastomeres contribute unequally to the human embryo	248
Spatial CRISPR genomics identifies regulators of the tumor microenvironment	247
Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy	246
Sleep is required to consolidate odor memory and remodel olfactory synapses	243
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals	243
Central nervous system regeneration	236
Nutrition, longevity and disease: From molecular mechanisms to interventions	233
The developmental basis of fingerprint pattern formation and variation	232
Hallmarks of neurodegenerative diseases	229
Small-molecule hypoxia therapy in mitochondrial disease	227
SnapShot: Cell size control	225
Gut microbiome ecological topology as next-generation biomarkers for cancer immunotherapy	224
Celebrating our origins with cell biology	223
ExSPECKt the unexpected: NLRP3-caspase-8-dependent cell death in RBCs	222
Intracellular calcium release: A conductor of compartmentalized dendritic plasticity	221
Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming	220
Immune checkpoint blockade provokes resident memory T cells to eliminate head and neck cancer	218
The genetic history of the Southern Caucasus from the Bronze Age to the Early Middle Ages: 5,000 years of genetic continuity despite high mobility	217
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia	217
Novel integrative elements and genomic plasticity in ocean ecosystems	214
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation	214
Pathogen protein modularity enables elaborate mimicry of a host phosphatase	214
Evolution of diapause in the African turquoise killifish by remodeling the ancient gene regulatory landscape	214
A generative deep learning approach to de novo antibiotic design	213
Engineered cell entry links receptor biology with single-cell genomics	212
An NK-like CAR T cell transition in CAR T cell dysfunction	212
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes	211
Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network	210
Unraveling Mendel’s final mysteries: A genomic retelling of pea genetics	209
Ultrafast distant wound response is essential for whole-body regeneration	206
Digital phenotyping from wearables using AI characterizes psychiatric disorders and identifies genetic associations	206
Virome characterization of game animals in China reveals a spectrum of emerging pathogens	202
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease	198
Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes	196
Multimodal charting of molecular and functional cell states via in situ electro-sequencing	194
Stereo-seq V2: Spatial mapping of total RNA on FFPE sections with high resolution	194
Mining metatranscriptomes reveals a vast world of viroid-like circular RNAs	194
Fine particle air pollution and lung cancer risk: Extending the long list of health risks	189
Small RNAs are modified with N-glycans and displayed on the surface of living cells	187
Freedom of expression: A synthetic route to metabolites	187
PIEZO2 in somatosensory neurons controls gastrointestinal transit	186
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution	185
Root microbiota regulates tiller number in rice	185
Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs	184
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays	184
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin	183
TGF-β signaling in health and disease	183
Tracing the origin of alveolar stem cells in lung repair and regeneration	182
Open-ST: High-resolution spatial transcriptomics in 3D	181
An Arabidopsis single-nucleus atlas decodes leaf senescence and nutrient allocation	179
Paul Berg and the origins of recombinant DNA	179
ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion	178
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques	177
Resmetirom for treatment of MASH	175
Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors	174

Nothing about us without us: Sharing results with communities that provide genomic data	174
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans	172
A multi-tissue metabolome atlas of primate pregnancy	172
Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants	172
Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity	172
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway	171
ER stress transforms random olfactory receptor choice into axon targeting precision	170
High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients	169
Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection	169
The genetic history of Scandinavia from the Roman Iron Age to the present	169
Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration	168
Intrinsic heterogeneity of primary cilia revealed through spatial proteomics	168
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling	167
Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation	167
A general chemical principle for creating closure-stabilizing integrin inhibitors	166
A neutrophil response linked to tumor control in immunotherapy	166
Atlas of the aging mouse brain reveals white matter as vulnerable foci	165
Comparative landscape of genetic dependencies in human and chimpanzee stem cells	165
Systematic profiling reveals betaine as an exercise mimetic for geroprotection	165
Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin	164
Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate	163
Induced epigenetic changes memorized across generations in mice	161
GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA	161
Exploring RNA-guided DNA scissors in eukaryotes: Are Fanzors counterparts of CRISPR-Cas12s?	160
Small STEPs toward a big change	160
Sensational channels	160
ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors	159
Unraveling mitochondrial influence on mammalian pluripotency via enforced mitophagy	159
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic	157
A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance	156
The human proteome with direct physical access to DNA	156
Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT	155
Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance	155
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice	154
Structural insights into auxin influx mediated by the Arabidopsis AUX1	154
Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution	152
Proteome-scale movements and compartment connectivity during the eukaryotic cell cycle	152
Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture	152
Ancient host-associated microbes obtained from mammoth remains	152
A widely distributed gene cluster compensates for uricase loss in hominids	152
Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates	151
Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels	151
Jumbo phage killer immune system targets early infection of nucleus-forming phages	151
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions	150
Spatial proteomics in neurons at single-protein resolution	150
A conserved family of immune effectors cleaves cellular ATP upon viral infection	149
Bispecific dendritic-T cell engager potentiates anti-tumor immunity	149
Mechanism of DNA capture by the MukBEF SMC complex and its inhibition by a viral DNA mimic	148
The extracellular matrix integrates mitochondrial homeostasis	148
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant	148
Overcoming drug resistance in cancer	148
Snapshot: Choroid plexus brain barrier	147
Cancer neuroscience: State of the field, emerging directions	147
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases	145
Macrophages in health and disease	145
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins	144
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures	144
Designing antibodies as therapeutics	143
Phage therapy: From biological mechanisms to future directions	143
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity	142
Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome	142
Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes	142
How to build the virtual cell with artificial intelligence: Priorities and opportunities	141
Chromosome-level organization of the regulatory genome in the Drosophila nervous system	141
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment	141
Human microglial state dynamics in Alzheimer’s disease progression	141
Problem choice and decision trees in science and engineering	140
Seven days in the life cycle of Homo sapiens	139
Opposing GPCR signaling programs protein intake setpoint in Drosophila	139
Structural studies put phage defense mystery on the RADAR	139
Cervicovaginal microbiome and natural history of Chlamydia trachomatis in adolescents and young women	139
Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes	139
Harnessing social media to challenge scientific misinformation	138
Staphylococcus scratches its itch	138
Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program	137
Learning lessons from lipids to make COVID-19 vaccines	137
Mast cells regulate the brain-dura interface and CSF dynamics	137
Global identification of SWI/SNF targets reveals compensation by EP400	136
Saturation mutagenesis-reinforced functional assays for disease-related genes	136
A percolation phase transition controls complement protein coating of surfaces	135
Medication effects on the gut microbiome in allo-HCT	134
Human monoclonal antibodies targeting A35 protect from death caused by mpox	133
Transport mechanism and pharmacology of the human GlyT1	133
Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer	132
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development	131
Before you call the midwife	130
How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot	130
Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants	130
Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease	130
Integrative spatial analysis reveals a multi-layered organization of glioblastoma	130
Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration	129
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer	128
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability	128
Bone marrow hematopoiesis drives multiple sclerosis progression	128
Microbial colonization programs are structured by breastfeeding and guide healthy respiratory development	128