Cell

Article	Citations
Response to: The information theory of aging has not been tested	3369
Global surveillance and countermeasures for ACE2-using MERS-related coronaviruses with spillover risk	1942
Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain	1155
The expanding world of neuroscience	1087
Patterning by contraction	975
Keiji Tanaka (1949–2024)	891
OLAH connects fatty acid metabolism to the severity of respiratory viral disease	869
A metabolic balance of GLP-1 and NMDA receptors in the brain	865
CAR T therapy extends its reach to autoimmune diseases	859
Functional diversification of dietary plant small molecules by the gut microbiome	787
Prying the lid open: Atomic-level insights on sialoglycan-TMPRSS2 coordination in HKU1 entry	762
Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses	760
Evolutionary assembly of cooperating cell types in an animal chemical defense system	750
Biosensors based on peptide exposure show single molecule conformations in live cells	679
Evolution and genetic adaptation of fishes to the deep sea	676
Muscle fusogens go viral for gene delivery to skeletal muscle	661
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite	656
A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation	625
Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias	622
Bound by the love for cholesterol: A transporter meets a GPCR	621
Learning from HBCUs: How to produce Black professionals in STEMM	586
Mesoscopic mapping of the brain: From rodents to primates	575
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations	573
Genomic architecture of autism from comprehensive whole-genome sequence annotation	572
Structure and infection dynamics of mycobacteriophage Bxb1	539

Structures of LRP2 reveal a molecular machine for endocytosis	510
Reply to Over-celling fetal microbial exposure	454
Channel synapse mediates neurotransmission of airway protective chemoreflexes	451
De novo assembly of nuclear stress bodies rearranges and enhances NFIL3 to restrain acute inflammatory responses	446
RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly	445
In vivo DNA replication dynamics unveil aging-dependent replication stress	444
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution	443
Structure-based discovery of CFTR potentiators and inhibitors	439
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center	439
Recycling of modified H2A-H2B provides short-term memory of chromatin states	428
EBV and MS: The evidence is growing stronger	427
In vitro human cell-based models: What can they do and what are their limitations?	426
Structural basis for Cas9 off-target activity	421
Local hyperthermia therapy induces browning of white fat and treats obesity	419
Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin	408
A deep learning strategy to identify cell types across species from high-density extracellular recordings	408
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells	405
Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants	401
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas	400
Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome	399
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma	396
Synthetic mammalian signaling circuits for robust cell population control	396
Structural specializations of the sperm tail	387
Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation	383
Ovarian cancer-derived IL-4 promotes immunotherapy resistance	380
A pan-cancer analysis of the microbiome in metastatic cancer	378
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility	377
Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic	366
Senescence-resistant human mesenchymal progenitor cells counter aging in primates	366
From periphery to center stage: 50 years of advancements in innate immunity	364
Macrophages at the interface of the co-evolving cancer ecosystem	363
Five decades of advances in cancer research	359
Choroid plexus mast cells drive tumor-associated hydrocephalus	356
Procr+ chondroprogenitors sense mechanical stimuli to govern articular cartilage maintenance and regeneration	353
Deciphering breast cancer: from biology to the clinic	352
PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development	341
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex	333
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells	325
A gut-retching discovery	325
How do DEI initiatives impact STEMM, and why do we still need them?	324
Precision medicine requires understanding how both sex and gender influence health	321
Influence of autozygosity on common disease risk across the phenotypic spectrum	319
Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration	318
Engineering RNA export for measurement and manipulation of living cells	317
SnapShot: Condensates in plant biology	311
To see is to experience: Aggression neurons light up when witnessing a fight	309
Fungal sugars boost vaccine protection	303
Cell surface fluctuations regulate early embryonic lineage sorting	300
Pursuing structural biology in China	299
The information theory of aging has not been tested	298

Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition	295
Building and supporting identity in peer review	293
Unrealized potential from smaller institutions: Four strategies for advancing STEM diversity	292
An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms	290
Structurally divergent and recurrently mutated regions of primate genomes	284
The developmental basis of fingerprint pattern formation and variation	281
Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding	280
Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease	277
Sleep is required to consolidate odor memory and remodel olfactory synapses	277
A genetic basis for sex differences in Xp11 translocation renal cell carcinoma	272
The first two blastomeres contribute unequally to the human embryo	269
Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity	269
The interferon landscape along the respiratory tract impacts the severity of COVID-19	269
Propofol: Milk of Amnesia	268
Gut-liver axis calibrates intestinal stem cell fitness	268
Infodemics: A new challenge for public health	267
Structural basis of respiratory complex adaptation to cold temperatures	267
Nutrition, longevity and disease: From molecular mechanisms to interventions	265
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs	261
Mechanism of IFT-A polymerization into trains for ciliary transport	260
Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy	252
A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement	251
Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1	250
A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior	249
Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic	247
Microglia maintain structural integrity during fetal brain morphogenesis	247
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals	246
HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity	245
It took a long, long time: Ras and the race to cure cancer	245
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification	243
Co-opting templated aggregation to degrade pathogenic tau assemblies and improve motor function	242
Central nervous system regeneration	241
Spatial CRISPR genomics identifies regulators of the tumor microenvironment	241
Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine	240
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients	239
Parallel and distributed encoding of speech across human auditory cortex	239
Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss	239
A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis	236
Ancient hybridization underlies tuberization and radiation of the potato lineage	236
Multi-layered computational gene networks by engineered tristate logics	235
Hallmarks of neurodegenerative diseases	234
Freedom of expression: A synthetic route to metabolites	233
Intracellular calcium release: A conductor of compartmentalized dendritic plasticity	231
Gut microbiome ecological topology as next-generation biomarkers for cancer immunotherapy	228
Celebrating our origins with cell biology	228
Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network	227
Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes	227
Fine particle air pollution and lung cancer risk: Extending the long list of health risks	225
SnapShot: Cell size control	225
Immune checkpoint blockade provokes resident memory T cells to eliminate head and neck cancer	224
Unraveling Mendel’s final mysteries: A genomic retelling of pea genetics	223
ExSPECKt the unexpected: NLRP3-caspase-8-dependent cell death in RBCs	223
Small-molecule hypoxia therapy in mitochondrial disease	223
Root microbiota regulates tiller number in rice	221
An Arabidopsis single-nucleus atlas decodes leaf senescence and nutrient allocation	221
Small RNAs are modified with N-glycans and displayed on the surface of living cells	220
Digital phenotyping from wearables using AI characterizes psychiatric disorders and identifies genetic associations	217
From microbial membrane proteins to the mysteries of emotion	215
Evolution of diapause in the African turquoise killifish by remodeling the ancient gene regulatory landscape	214
PIEZO2 in somatosensory neurons controls gastrointestinal transit	213
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation	210
Pathogen protein modularity enables elaborate mimicry of a host phosphatase	210
Multimodal charting of molecular and functional cell states via in situ electro-sequencing	208
An NK-like CAR T cell transition in CAR T cell dysfunction	208
Open-ST: High-resolution spatial transcriptomics in 3D	207
Tracing the origin of alveolar stem cells in lung repair and regeneration	202
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution	202
Engineered cell entry links receptor biology with single-cell genomics	201
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin	200
Mining metatranscriptomes reveals a vast world of viroid-like circular RNAs	199
Virome characterization of game animals in China reveals a spectrum of emerging pathogens	196
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease	196
Novel integrative elements and genomic plasticity in ocean ecosystems	194
Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer	193
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays	192
Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs	191
Ultrafast distant wound response is essential for whole-body regeneration	191
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes	188
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality	187
Small STEPs toward a big change	186

TGF-β signaling in health and disease	186
Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT	184
Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors	183
Sensational channels	183
Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture	182
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice	181
Jumbo phage killer immune system targets early infection of nucleus-forming phages	180
Comparative landscape of genetic dependencies in human and chimpanzee stem cells	180
Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance	179
Emergence of an early SARS-CoV-2 epidemic in the United States	179
Unraveling mitochondrial influence on mammalian pluripotency via enforced mitophagy	178
Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome	177
Induced epigenetic changes memorized across generations in mice	177
A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance	176
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic	175
ATG8-Binding UIM Proteins Define a New Class of Autophagy Adaptors and Receptors	174
Paul Berg and the origins of recombinant DNA	173
Overcoming drug resistance in cancer	172
Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin	172
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques	172
Snapshot: Choroid plexus brain barrier	171
Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution	170
Chromosome-level organization of the regulatory genome in the Drosophila nervous system	170
Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation	169
The extracellular matrix integrates mitochondrial homeostasis	169
A neutrophil response linked to tumor control in immunotherapy	168
The human proteome with direct physical access to DNA	168
ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion	168
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling	168
Structural insights into auxin influx mediated by the Arabidopsis AUX1	167
Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate	167
Bispecific dendritic-T cell engager potentiates anti-tumor immunity	167
Nothing about us without us: Sharing results with communities that provide genomic data	166
A widely distributed gene cluster compensates for uricase loss in hominids	165
Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion	163
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans	163
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway	162
Mechanism of DNA capture by the MukBEF SMC complex and its inhibition by a viral DNA mimic	160
Designing antibodies as therapeutics	158
Hippocampal neurons construct a map of an abstract value space	158
Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes	157
A general chemical principle for creating closure-stabilizing integrin inhibitors	156
Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants	156
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity	156
Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates	155
Spatial proteomics in neurons at single-protein resolution	154
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant	153
GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA	153
High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients	153
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins	152
Exploring RNA-guided DNA scissors in eukaryotes: Are Fanzors counterparts of CRISPR-Cas12s?	152
The genetic history of Scandinavia from the Roman Iron Age to the present	152
A conserved family of immune effectors cleaves cellular ATP upon viral infection	152
Human microglial state dynamics in Alzheimer’s disease progression	150
Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels	149
ER stress transforms random olfactory receptor choice into axon targeting precision	149
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases	149
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions	149
Macrophages in health and disease	148
Phage therapy: From biological mechanisms to future directions	148
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures	147
How to build the virtual cell with artificial intelligence: Priorities and opportunities	146
A multi-tissue metabolome atlas of primate pregnancy	146
Lrp1 is a host entry factor for Rift Valley fever virus	146
Resmetirom for treatment of MASH	144
Proteome-scale movements and compartment connectivity during the eukaryotic cell cycle	143
Cancer neuroscience: State of the field, emerging directions	142
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment	142
Atlas of the aging mouse brain reveals white matter as vulnerable foci	142
Before you call the midwife	141
Structural studies put phage defense mystery on the RADAR	141
First come, first served: Mammalian recombination is timed to replication	141
Harnessing social media to challenge scientific misinformation	141
How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot	139
Cervicovaginal microbiome and natural history of Chlamydia trachomatis in adolescents and young women	139
Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress	139
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability	139
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response	138
Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer	137
Integrative spatial analysis reveals a multi-layered organization of glioblastoma	137
Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer	136
TDP-43 condensation properties specify its RNA-binding and regulatory repertoire	136
Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease	135
Global identification of SWI/SNF targets reveals compensation by EP400	135
Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations	135
Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants	134
A percolation phase transition controls complement protein coating of surfaces	134
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling	133
Learning lessons from lipids to make COVID-19 vaccines	133
Problem choice and decision trees in science and engineering	133
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development	132
Transport mechanism and pharmacology of the human GlyT1	132
A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors	132
Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes	132
Seven days in the life cycle of Homo sapiens	132