Cell

Papers
(The median citation count of Cell is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor15049
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein5908
Integrated analysis of multimodal single-cell data5826
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus3351
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-193351
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals2776
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE22090
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues1778
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE21721
Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding1654
The Architecture of SARS-CoV-2 Transcriptome1640
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-191442
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity1429
Adaptive immunity to SARS-CoV-2 and COVID-191308
The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity1301
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract1197
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology1132
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells1084
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment1081
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera1079
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity1035
Hallmarks of aging: An expanding universe915
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes895
Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera888
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant869
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2827
SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies816
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant795
The Global Phosphorylation Landscape of SARS-CoV-2 Infection789
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity773
Molecular Architecture of the SARS-CoV-2 Virus765
Mechanisms and disease consequences of nonalcoholic fatty liver disease753
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications748
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses741
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2719
Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer712
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules699
The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic687
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies683
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers665
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19644
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19637
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase633
Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer598
A Genomic Perspective on the Origin and Emergence of SARS-CoV-2597
Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2593
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy591
Multiple early factors anticipate post-acute COVID-19 sequelae591
Hallmarks of response, resistance, and toxicity to immune checkpoint blockade591
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin578
SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron568
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum568
Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery561
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells556
COVID-19-neutralizing antibodies predict disease severity and survival554
Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19553
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation552
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells550
Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography547
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization539
The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas537
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19532
Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum520
Plant Immunity: Danger Perception and Signaling518
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein509
COVID-19 and the human innate immune system509
Pan-Genome of Wild and Cultivated Soybeans505
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity499
Antibody evasion by the P.1 strain of SARS-CoV-2489
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2481
Gut-microbiota-targeted diets modulate human immune status477
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease476
Targeting Strategies for Tissue-Specific Drug Delivery475
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition473
A Thermostable mRNA Vaccine against COVID-19470
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas469
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies467
Effects of COVID-19 on the Nervous System464
A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation460
Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato457
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice452
Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants450
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome450
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma449
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells448
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS447
Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies444
Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19436
A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA436
A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2435
Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera433
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses431
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays430
Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front424
β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway420
Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer420
High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue415
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2409
Genome engineering for crop improvement and future agriculture406
Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)404
The Science of Antibiotic Discovery400
A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS399
Emerging Pandemic Diseases: How We Got to COVID-19398
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma395
Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19394
Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes383
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients382
Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma381
The Polygenic and Monogenic Basis of Blood Traits and Diseases378
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant378
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection377
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment375
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart359
Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2353
The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease351
Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing351
Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex350
Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution350
Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease349
The basic immunology of asthma348
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations348
Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection348
Antidepressant drugs act by directly binding to TRKB neurotrophin receptors344
A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer342
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches341
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity340
The Self-Organizing Genome: Principles of Genome Architecture and Function338
Fibroblasts: Origins, definitions, and functions in health and disease337
Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage332
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes331
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity331
Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza330
Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma328
The origins of SARS-CoV-2: A critical review323
Massive expansion of human gut bacteriophage diversity323
Molecular topography of an entire nervous system322
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution320
RNA-Mediated Feedback Control of Transcriptional Condensates319
Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear319
The antigenic anatomy of SARS-CoV-2 receptor binding domain318
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape315
A Genetic Map of the Response to DNA Damage in Human Cells315
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis312
Atherosclerosis: Recent developments310
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing310
Bifidobacteria-mediated immune system imprinting early in life309
The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling307
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy307
Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron305
Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin303
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection299
Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses298
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer298
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice296
Functional characterization of the dural sinuses as a neuroimmune interface295
Circular RNAs: Characterization, cellular roles, and applications294
Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States290
Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer288
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells286
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model286
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks286
CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors284
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein284
The Human and Mouse Enteric Nervous System at Single-Cell Resolution284
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection283
Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells280
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction280
Integrative Proteomic Characterization of Human Lung Adenocarcinoma279
Tackling COVID-19 with neutralizing monoclonal antibodies275
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis275
The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway272
Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients271
How Machine Learning Will Transform Biomedicine271
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy271
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor269
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity268
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema267
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly267
Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies266
Humoral and cellular immune memory to four COVID-19 vaccines266
Multi-organ proteomic landscape of COVID-19 autopsies264
Spatiotemporal analysis of human intestinal development at single-cell resolution264
Generation of Functional Human 3D Cortico-Motor Assembloids262
High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios261
Endometriosis: Etiology, pathobiology, and therapeutic prospects261
Small RNAs are modified with N-glycans and displayed on the surface of living cells261
Molecular Choreography of Acute Exercise260
Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate257
A route to de novo domestication of wild allotetraploid rice256
Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy256
Adipose-tissue plasticity in health and disease254
Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality254
Spatially organized multicellular immune hubs in human colorectal cancer254
The Rise of Molecular Glues253
Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy253
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression252
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes251
Maturation and persistence of the anti-SARS-CoV-2 memory B cell response251
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins248
Telomeres: history, health, and hallmarks of aging247
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense246
Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States245
The Emerging Landscape of Immune Cell Therapies245
Co-option of Neutrophil Fates by Tissue Environments245
Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb244
The Tolman-Eichenbaum Machine: Unifying Space and Relational Memory through Generalization in the Hippocampal Formation243
Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination242
Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine242
Mitochondrial Diseases: Hope for the Future236
Hallmarks of Health236
A Quantitative Proteome Map of the Human Body233
Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike233
Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut233
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations232
Hallmarks of neurodegenerative diseases230
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output230
Microscopic examination of spatial transcriptome using Seq-Scope229
Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses228
SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2228
Proteogenomic characterization of pancreatic ductal adenocarcinoma228
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients228
Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment226
Impact of GPCR Structures on Drug Discovery226
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation226
Personalized Mapping of Drug Metabolism by the Human Gut Microbiome222
Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy220
Cardioids reveal self-organizing principles of human cardiogenesis219
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies219
Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development216
Genomic Epidemiology of SARS-CoV-2 in Guangdong Province, China216
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system213
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution208
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis208
Bacterial Retrons Function In Anti-Phage Defense207
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans207
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer206
Circular RNA vaccines against SARS-CoV-2 and emerging variants206
Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome202
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway201
A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance201
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer200
Metabolic modeling of single Th17 cells reveals regulators of autoimmunity200
Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition199
The Geometry of Abstraction in the Hippocampus and Prefrontal Cortex198
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis194
A single-cell atlas of chromatin accessibility in the human genome193
Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species192
Nitric oxide signaling in health and disease192
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19189
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells189
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