(The H4-Index of Cell is 217. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-09-01 to 2023-09-01.)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor14101
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein5571
Integrated analysis of multimodal single-cell data3839
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus3175
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-193135
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals2599
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE21953
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues1676
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE21624
Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding1508
The Architecture of SARS-CoV-2 Transcriptome1507
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies1357
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-191348
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity1307
The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity1225
Cellular Senescence: Defining a Path Forward1225
Adaptive immunity to SARS-CoV-2 and COVID-191149
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism1141
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract1075
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells1030
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology1011
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera968
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment967
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity960
Toll-like Receptors and the Control of Immunity858
Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera847
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant814
SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies776
The Role of Non-coding RNAs in Oncology771
A Deep Learning Approach to Antibiotic Discovery768
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders751
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2741
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity727
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes722
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant703
The Global Phosphorylation Landscape of SARS-CoV-2 Infection702
Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma692
Molecular Architecture of the SARS-CoV-2 Virus650
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses644
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2643
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies642
Organization of Chromatin by Intrinsic and Regulated Phase Separation613
Microglia Biology: One Century of Evolving Concepts608
Single-Cell Transcriptome Atlas of Murine Endothelial Cells602
The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic601
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase598
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19590
A Genomic Perspective on the Origin and Emergence of SARS-CoV-2574
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19572
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules558
Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer558
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers551
Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2548
Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer537
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum533
Mechanisms and disease consequences of nonalcoholic fatty liver disease528
Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19508
COVID-19-neutralizing antibodies predict disease severity and survival501
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19499
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy495
Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography486
Quantitative Proteomics of the Cancer Cell Line Encyclopedia485
Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery480
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity472
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization466
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation466
SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron463
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin459
Antibody evasion by the P.1 strain of SARS-CoV-2457
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein454
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells450
COVID-19 and the human innate immune system446
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity445
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2445
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies444
Effects of COVID-19 on the Nervous System429
Plant Immunity: Danger Perception and Signaling415
Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera412
Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy412
Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies411
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma411
Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum410
Multiple early factors anticipate post-acute COVID-19 sequelae408
A Thermostable mRNA Vaccine against COVID-19407
The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas404
Pan-Genome of Wild and Cultivated Soybeans401
Hallmarks of response, resistance, and toxicity to immune checkpoint blockade398
A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart398
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease394
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells393
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells387
Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19384
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition383
A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2383
Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato379
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas376
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice375
Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)371
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications370
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses368
β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway359
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2357
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma355
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment354
A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA352
Gut-microbiota-targeted diets modulate human immune status349
A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS349
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant348
Targeting Strategies for Tissue-Specific Drug Delivery347
Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer344
Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans344
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients343
Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19341
Emerging Pandemic Diseases: How We Got to COVID-19341
Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations337
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome336
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS334
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection334
Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes331
Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection324
Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma323
Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front321
High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue321
Hallmarks of aging: An expanding universe320
A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation318
R Loops: From Physiological to Pathological Roles317
A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors316
Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells313
Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex312
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma311
Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear307
The Science of Antibiotic Discovery305
Genome engineering for crop improvement and future agriculture300
Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza299
Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis298
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape298
Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism298
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity296
The Polygenic and Monogenic Basis of Blood Traits and Diseases295
The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease294
Conversion of Escherichia coli to Generate All Biomass Carbon from CO2292
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations287
Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution285
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart283
Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2282
Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain282
Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage280
Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing279
A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer279
Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States278
The origins of SARS-CoV-2: A critical review277
Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents277
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity277
Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma276
The antigenic anatomy of SARS-CoV-2 receptor binding domain275
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether269
RNA-Mediated Feedback Control of Transcriptional Condensates269
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model269
The Self-Organizing Genome: Principles of Genome Architecture and Function269
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity268
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution266
Genomes of Subaerial Zygnematophyceae Provide Insights into Land Plant Evolution265
Massive expansion of human gut bacteriophage diversity264
Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease263
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection263
Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses259
A Genetic Map of the Response to DNA Damage in Human Cells257
Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin256
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice255
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein255
The basic immunology of asthma255
Antidepressant drugs act by directly binding to TRKB neurotrophin receptors255
Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients252
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks252
Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron251
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection250
Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma247
The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling247
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer247
B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer246
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy246
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains245
CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors245
Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program244
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing243
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays242
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells239
Functional characterization of the dural sinuses as a neuroimmune interface238
Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner238
Tackling COVID-19 with neutralizing monoclonal antibodies235
Molecular topography of an entire nervous system235
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly234
The Human and Mouse Enteric Nervous System at Single-Cell Resolution234
Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis233
Proteogenomic Characterization of Endometrial Carcinoma233
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes233
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis231
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches231
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema231
Phase Separation of Zonula Occludens Proteins Drives Formation of Tight Junctions229
Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality229
Single-Cell Transcriptomic Atlas of Primate Ovarian Aging229
Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants228
Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States227
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction226
UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma224
Global Trends in Marine Plankton Diversity across Kingdoms of Life224
Genetic Identification of Vagal Sensory Neurons That Control Feeding223
Fibroblasts: Origins, definitions, and functions in health and disease222
Bifidobacteria-mediated immune system imprinting early in life222
Maturation and persistence of the anti-SARS-CoV-2 memory B cell response221
Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine219
Multi-organ proteomic landscape of COVID-19 autopsies218
The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway218
Gene Expression Changes and Community Turnover Differentially Shape the Global Ocean Metatranscriptome218
Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies218
Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy217