OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacology Biochemistry and Behavior is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Effect of alcohol use on the adolescent brain and behavior	163
Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats	99
A review of psychosocial factors linked to adolescent substance use	83
Unique, long-term effects of nicotine on adolescent brain	73
Sex differences and the endocannabinoid system in pain	62
pMAT: An open-source software suite for the analysis of fiber photometry data	61
Differential impact of stress and environmental enrichment on corticolimbic circuits	42
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression	39
Object recognition and Morris water maze to detect cognitive impairment from mild hippocampal damage in rats: A reflection based on the literature and experience	39
Circadian rhythms and substance use disorders: A bidirectional relationship	31
Sleep and alertness disturbance and substance use disorders: A bi-directional relation	29
Tolerance to alcohol: A critical yet understudied factor in alcohol addiction	29
A selected review of recent advances in the study of neuronal circuits using fiber photometry	28
The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders	27
Therapeutic potential and safety considerations for the clinical use of synthetic cannabinoids	27
Long-term maternal separation potentiates depressive-like behaviours and neuroinflammation in adult male C57/BL6J mice	26
Use and abuse of dissociative and psychedelic drugs in adolescence	26
The involvement of PI3K/Akt/mTOR/GSK3β signaling pathways in the antidepressant-like effect of AZD6765	25
Neural mechanisms underlying incubation of methamphetamine craving: A mini-review	25
The structural reorganization of the prefrontal cortex during adolescence as a framework for vulnerability to the environment	24
Inflammation and early life stress: An updated review of childhood trauma and inflammatory markers in adulthood	24
Prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor associated-genes in the prefronta	24
Neuronal brain injury after cerebral ischemic stroke is ameliorated after subsequent administration of (R)-ketamine, but not (S)-ketamine	22
Environmental enrichment and its influence on rodent offspring and maternal behaviours, a scoping style review of indices of depression and anxiety	21
Cortical and raphe GABAA, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine	21

Appetitive, antinociceptive, and hypothermic effects of vaped and injected Δ-9-tetrahydrocannabinol (THC) in rats: exposure and dose-effect comparisons by strain and sex	20
Opioid receptor system contributes to the acute and sustained antidepressant-like effects, but not the hyperactivity motor effects of ketamine in mice	19
Rapid antidepressant-like effect of non-hallucinogenic psychedelic analog lisuride, but not hallucinogenic psychedelic DOI, in lipopolysaccharide-treated mice	18
Gut microbiota is involved in the antidepressant-like effect of (S)-norketamine in an inflammation model of depression	18
Female rats self-administer heroin by vapor inhalation	18
Evaluation of the potential use of cannabidiol in the treatment of cocaine use disorder: A systematic review	18
Classic and evolving animal models in Parkinson's disease	18
Cholecalciferol abolishes depressive-like behavior and hippocampal glucocorticoid receptor impairment induced by chronic corticosterone administration in mice	18
Clopidogrel combats neuroinflammation and enhances learning behavior and memory in a rat model of Alzheimer's disease	18
Cannabidiol (CBD) reduces cocaine-environment memory in mice	18
Impact of specific serotonin receptor modulation on behavioral flexibility	17
Fentanyl-related substances elicit antinociception and hyperlocomotion in mice via opioid receptors	17
Acute and residual mood and cognitive performance of young adults following smoked cannabis	17
Transmission of the adverse consequences of childhood maltreatment across generations: Focus on gestational biology	17
The importance of child abuse and neglect in adult medicine	17
Early life stress and substance use disorders: The critical role of adolescent substance use	16
Serotonin 6 receptor blockade reduces repetitive behavior in the BTBR mouse model of autism spectrum disorder	16
Targeting the renin angiotensin system for the treatment of anxiety and depression	16
Exercise and fluoxetine treatment during adolescence protect against early life stress-induced behavioral abnormalities in adult rats	16
Non-pharmacological and pharmacological approaches for psychiatric disorders: Re-appraisal and insights from zebrafish models	16
Interaction between cocaine use and sleep behavior: A comprehensive review of cocaine's disrupting influence on sleep behavior and sleep disruptions influence on reward seeking	15
Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity	15
Divergent profiles of fentanyl withdrawal and associated pain in mice and rats	15
Unique effects of nicotine across the lifespan	15
Treating cocaine and opioid use disorder with transcranial magnetic stimulation: A path forward	15
Association of autism with toxic metals: A systematic review of case-control studies	15
Progress in opioid reward research: From a canonical two-neuron hypothesis to two neural circuits	15
Reinforcing effects of synthetic cathinones in rhesus monkeys: Dose-response and behavioral economic analyses	14
Orexins role in neurodegenerative diseases: From pathogenesis to treatment	14
Sucrose intake and preference by Wistar Han rats are not influenced by sex or food/water deprivation	14
Neuroinflammation in psychiatric disorders: An introductory primer	14
α7nAChR activation protects against oxidative stress, neuroinflammation and central insulin resistance in ICV-STZ induced sporadic Alzheimer's disease	14
Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery	14
Effect of child abuse and neglect on schizophrenia and other psychotic disorders	13
Exposure to smoke from high- but not low-nicotine cigarettes leads to signs of dependence in male rats and potentiates the effects of nicotine in female rats	13
Behavioral plasticity and gene regulation in the brain during an intermittent ethanol exposure in adult zebrafish population	13
The α2,3-selective potentiators of GABAA receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without tolerance development	13
Ketamine metabolite (2R,6R)-hydroxynorketamine reverses behavioral despair produced by adolescent trauma	13
Chronic aerobic exercise: Autoradiographic assessment of GABA(a) and mu-opioid receptor binding in adult rats	13
Influence of n-acetylcysteine maintenance on the pharmacodynamic effects of oral ethanol	13
Novel fatty acid-binding protein 3 ligand inhibits dopaminergic neuronal death and improves motor and cognitive impairments in Parkinson's disease model mice	13
Clinical investigations of compounds targeting metabotropic glutamate receptors	12
R-(−)-ketamine modifies behavioral effects of morphine predicting efficacy as a novel therapy for opioid use disorder1	12
Analgesic treatment with buprenorphine should be adapted to the mouse strain	12
Activation of GPR55 attenuates cognitive impairment, oxidative stress, neuroinflammation, and synaptic dysfunction in a streptozotocin-induced Alzheimer's mouse model	12
Review of addiction risk potential associated with adolescent opioid use	12
Confronting the challenge of failed translation in medications development for substance use disorders	12
Adolescent-onset vs. adult-onset cocaine use: Impact on cognitive functioning in animal models and opportunities for translation	11
Going beyond risk factor: Childhood maltreatment and associated modifiable targets to improve life-long outcomes in mood disorders	11
Dopamine D1 or D3 receptor modulators prevent morphine tolerance and reduce opioid withdrawal symptoms	11

Scaffold hopping of agomelatine leads to enhanced antidepressant effects by modulation of gut microbiota and host immune responses	11
Early life stress induced by maternal separation during lactation alters the eating behavior and serotonin system in middle-aged rat female offspring	11
Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine	11
Conditioned place preference following concurrent treatment with 3, 4-methylenedioxypyrovalerone (MDPV) and methamphetamine in male and female Sprague-Dawley rats	11
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats	11
The effects of caffeinated products on sleep and functioning in the military population: A focused review	11
Agmatine reverses memory deficits induced by Aβ1–42 peptide in mice: A key role of imidazoline receptors	11
Inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes from adolescence to adulthood	11
Reinforcing and discriminative-stimulus effects of two pyrrolidine-containing synthetic cathinone derivatives in rats	11
Intoxication by a synthetic cannabinoid (JWH-018) causes cognitive and psychomotor impairment in recreational cannabis users	11
Chronic cannabidiol (CBD) treatment did not exhibit beneficial effects in 4-month-old male TAU58/2 transgenic mice	11
Long-term effects of prenatal cannabis exposure: Pathways to adolescent and adult outcomes	11
Early adversity as the prototype gene × environment interaction in mental disorders?	11
Environmental enrichment modulates affiliative and aggressive social behaviour in the neuroligin-3 R451C mouse model of autism spectrum disorder	11
Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine	11
Adolescent nicotine treatment causes robust locomotor sensitization during adolescence but impedes the spontaneous acquisition of nicotine intake in adult female Wistar rats	11
Combined induction of mTOR-dependent and mTOR-independent pathways of autophagy activation as an experimental therapy for Alzheimer's disease-like pathology in a mouse model	11
Translational PET applications for brain circuit mapping with transgenic neuromodulation tools	11
Female rats display higher methamphetamine-primed reinstatement and c-Fos immunoreactivity than male rats	10
Nicotine-free vapor inhalation produces behavioral disruptions and anxiety-like behaviors in mice: Effects of puff duration, session length, sex, and flavor	10
Magnetic resonance spectroscopy studies of substance use disorders: Current landscape and potential future directions	10
Danavorexton, a selective orexin 2 receptor agonist, provides a symptomatic improvement in a narcolepsy mouse model	10
Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish	10
Sex-related differences in intravenous ketamine effects on dissociative stereotypy and antinociception in male and female rats	10
In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018	10
In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists	10
The importance of pH: How aquarium water is affecting behavioural responses to drug exposure in larval zebrafish	10
HDAC inhibitors reverse mania-like behavior and modulate epigenetic regulatory enzymes in an animal model of mania induced by Ouabain	10
Distinct cognitive and discriminative stimulus effects of ketamine enantiomers in rats	10
Prenatal and adolescent alcohol exposure programs immunity across the lifespan: CNS-mediated regulation	10
NPY-Y1 receptors in dorsal periaqueductal gray modulate anxiety, alcohol intake, and relapse in Wistar rats	10
Long-term exposure to constant light induces dementia, oxidative stress and promotes aggregation of sub-pathological Aβ42 in Wistar rats	10
Multiomic biological approaches to the study of child abuse and neglect	9
Minocycline attenuates oxycodone-induced positive subjective responses in non-dependent, recreational opioid users	9
Alpha 7 nicotinic receptor agonist and positive allosteric modulators improved social and molecular deficits of MK-801 model of schizophrenia in rats	9
Taurine-mediated aggression is abolished via 5-HT1A antagonism and serotonin depletion in zebrafish	9
REM sleep deprivation before extinction or reinstatement alters methamphetamine reward memory via D1-like dopamine receptors	9
Antidepressant-like actions of the mGlu2/3 receptor antagonist TP0178894 in the chronic social defeat stress model: Comparison with escitalopram	9
Antihyperalgesic effects of intrathecal perospirone in a rat model of neuropathic pain	9
Sleep, psychiatric and socioeconomic factors associated with substance use in a large population sample: A cross-sectional study	9
Acute caffeine ingestion improves 3-km run performance, cognitive function, and psychological state of young recreational runners	9
Untapped endocannabinoid pharmacological targets: Pipe dream or pipeline?	9
High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone	9
Swimming exercise reduces the vulnerability to stress and contributes to the AKT/GSK3β/CRMP2 pathway and microtubule dynamics mediated protective effects on neuroplasticity in male C57BL/6 mice	9
The neurobiology of abstinence-induced reward-seeking in males and females	9
Chronic lithium exposure attenuates ketamine-induced mania-like behavior and c-Fos expression in the forebrain of mice	9
Do greater levels of in-cage waking inactivity in laboratory mice reflect a spontaneous depression-like symptom? A pharmacological investigation	9
Nicotine and the developing brain: Insights from preclinical models	8
Taurine modulates behavioral effects of intermittent ethanol exposure without changing brain monoamine oxidase activity in zebrafish: Attenuation of shoal- and anxiety-like responses, and abolishment	8
The multimodal serotonin compound Vilazodone alone, but not combined with the glutamate antagonist Amantadine, reduces l-DOPA-induced dyskinesia in hemiparkinsonian rats	8
Temporary inactivation of the infralimbic cortex impairs while the blockade of its dopamine D2 receptors enhances auditory fear extinction in rats	8
Blockade of kappa-opioid receptors amplifies microglia-mediated inflammatory responses	8
Arachidonyl-2′-chloroethylamide (ACEA), a synthetic agonist of cannabinoid receptor, increases CB1R gene expression and reduces dyskinesias in a rat model of Parkinson's disease	8
Increased alcohol self-administration following repeated Toll-like receptor 3 agonist treatment in male and female rats	8
Modern approaches to the development of synthetic cannabinoid receptor probes	8
The non-selective adenosine antagonist theophylline reverses the effects of dopamine antagonism on tremor, motor activity and effort-based decision-making	8
Differential effects of modafinil on performance of low-performing and high-performing individuals during total sleep deprivation	8
Sex differences in the rodent hippocampal opioid system following stress and oxycodone associated learning processes	8
Deletion of VGLUT2 in midbrain dopamine neurons attenuates dopamine and glutamate responses to methamphetamine in mice	8
The blockade of D1- and D2-like dopamine receptors within the dentate gyrus attenuates food deprivation stress-induced reinstatement of morphine-extinguished conditioned place preference in rats	8
AMPed-up adolescents: The role of age in the abuse of amphetamines and its consequences on cognition and prefrontal cortex development	8