OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacology Biochemistry and Behavior is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats	116
pMAT: An open-source software suite for the analysis of fiber photometry data	73
Sex differences and the endocannabinoid system in pain	72
Object recognition and Morris water maze to detect cognitive impairment from mild hippocampal damage in rats: A reflection based on the literature and experience	54
Tolerance to alcohol: A critical yet understudied factor in alcohol addiction	39
Sleep and alertness disturbance and substance use disorders: A bi-directional relation	36
A selected review of recent advances in the study of neuronal circuits using fiber photometry	34
The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders	33
The structural reorganization of the prefrontal cortex during adolescence as a framework for vulnerability to the environment	33
Circadian rhythms and substance use disorders: A bidirectional relationship	33
Inflammation and early life stress: An updated review of childhood trauma and inflammatory markers in adulthood	32
Therapeutic potential and safety considerations for the clinical use of synthetic cannabinoids	31
Use and abuse of dissociative and psychedelic drugs in adolescence	30
The involvement of PI3K/Akt/mTOR/GSK3β signaling pathways in the antidepressant-like effect of AZD6765	29
Neural mechanisms underlying incubation of methamphetamine craving: A mini-review	28
Rapid antidepressant-like effect of non-hallucinogenic psychedelic analog lisuride, but not hallucinogenic psychedelic DOI, in lipopolysaccharide-treated mice	26
Early life stress and substance use disorders: The critical role of adolescent substance use	24
Impact of specific serotonin receptor modulation on behavioral flexibility	24
Classic and evolving animal models in Parkinson's disease	24
Divergent profiles of fentanyl withdrawal and associated pain in mice and rats	23
Cannabidiol (CBD) reduces cocaine-environment memory in mice	22
Opioid receptor system contributes to the acute and sustained antidepressant-like effects, but not the hyperactivity motor effects of ketamine in mice	22
Appetitive, antinociceptive, and hypothermic effects of vaped and injected Δ-9-tetrahydrocannabinol (THC) in rats: exposure and dose-effect comparisons by strain and sex	22
Activation of GPR55 attenuates cognitive impairment, oxidative stress, neuroinflammation, and synaptic dysfunction in a streptozotocin-induced Alzheimer's mouse model	22
Transmission of the adverse consequences of childhood maltreatment across generations: Focus on gestational biology	21

Targeting the renin angiotensin system for the treatment of anxiety and depression	20
Fentanyl-related substances elicit antinociception and hyperlocomotion in mice via opioid receptors	20
Progress in opioid reward research: From a canonical two-neuron hypothesis to two neural circuits	20
The importance of child abuse and neglect in adult medicine	19
Association of autism with toxic metals: A systematic review of case-control studies	19
Gut microbiota is involved in the antidepressant-like effect of (S)-norketamine in an inflammation model of depression	19
Female rats self-administer heroin by vapor inhalation	19
Treating cocaine and opioid use disorder with transcranial magnetic stimulation: A path forward	18
Sucrose intake and preference by Wistar Han rats are not influenced by sex or food/water deprivation	18
Clinical investigations of compounds targeting metabotropic glutamate receptors	18
Interaction between cocaine use and sleep behavior: A comprehensive review of cocaine's disrupting influence on sleep behavior and sleep disruptions influence on reward seeking	18
Exercise and fluoxetine treatment during adolescence protect against early life stress-induced behavioral abnormalities in adult rats	18
Combined induction of mTOR-dependent and mTOR-independent pathways of autophagy activation as an experimental therapy for Alzheimer's disease-like pathology in a mouse model	18
Unique effects of nicotine across the lifespan	17
Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine	16
α7nAChR activation protects against oxidative stress, neuroinflammation and central insulin resistance in ICV-STZ induced sporadic Alzheimer's disease	16
Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery	16
Serotonin 6 receptor blockade reduces repetitive behavior in the BTBR mouse model of autism spectrum disorder	16
Long-term effects of prenatal cannabis exposure: Pathways to adolescent and adult outcomes	16
Reinforcing effects of synthetic cathinones in rhesus monkeys: Dose-response and behavioral economic analyses	15
Review of addiction risk potential associated with adolescent opioid use	14
Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine	14
Effect of child abuse and neglect on schizophrenia and other psychotic disorders	14
Confronting the challenge of failed translation in medications development for substance use disorders	14
The effects of caffeinated products on sleep and functioning in the military population: A focused review	13
In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists	13
Going beyond risk factor: Childhood maltreatment and associated modifiable targets to improve life-long outcomes in mood disorders	13
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats	13
Influence of n-acetylcysteine maintenance on the pharmacodynamic effects of oral ethanol	13
Minocycline attenuates oxycodone-induced positive subjective responses in non-dependent, recreational opioid users	12
Taurine-mediated aggression is abolished via 5-HT1A antagonism and serotonin depletion in zebrafish	12
Conditioned place preference following concurrent treatment with 3, 4-methylenedioxypyrovalerone (MDPV) and methamphetamine in male and female Sprague-Dawley rats	12
Sex-related differences in intravenous ketamine effects on dissociative stereotypy and antinociception in male and female rats	12
Intoxication by a synthetic cannabinoid (JWH-018) causes cognitive and psychomotor impairment in recreational cannabis users	12
REM sleep deprivation before extinction or reinstatement alters methamphetamine reward memory via D1-like dopamine receptors	12
Danavorexton, a selective orexin 2 receptor agonist, provides a symptomatic improvement in a narcolepsy mouse model	12
Substance use, microbiome and psychiatric disorders	12
Inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes from adolescence to adulthood	12
Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra	12
Fentanyl analog structure-activity relationships demonstrate determinants of diverging potencies for antinociception and respiratory depression	12
Do greater levels of in-cage waking inactivity in laboratory mice reflect a spontaneous depression-like symptom? A pharmacological investigation	12
Female rats display higher methamphetamine-primed reinstatement and c-Fos immunoreactivity than male rats	12
Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish	11
What was learned from studying the effects of early institutional deprivation	11
Prenatal and adolescent alcohol exposure programs immunity across the lifespan: CNS-mediated regulation	11
Acute caffeine ingestion improves 3-km run performance, cognitive function, and psychological state of young recreational runners	11
Early adversity as the prototype gene × environment interaction in mental disorders?	11
Cannabidiol effects on cognition in individuals with cocaine use disorder: Exploratory results from a randomized controlled trial	11
The G-protein biased kappa opioid agonists, triazole 1.1 and nalfurafine, produce non-uniform behavioral effects in male rhesus monkeys	11
Group III metabotropic glutamate receptors as promising targets for neuroprotective therapy: Particular emphasis on the role of mGlu4 and mGlu7 receptors	11

Reinforcing and discriminative-stimulus effects of two pyrrolidine-containing synthetic cathinone derivatives in rats	11
Translational PET applications for brain circuit mapping with transgenic neuromodulation tools	11
Antidepressant-like actions of the mGlu2/3 receptor antagonist TP0178894 in the chronic social defeat stress model: Comparison with escitalopram	11
Increased alcohol self-administration following repeated Toll-like receptor 3 agonist treatment in male and female rats	11
Adolescent nicotine treatment causes robust locomotor sensitization during adolescence but impedes the spontaneous acquisition of nicotine intake in adult female Wistar rats	11
Sleep, psychiatric and socioeconomic factors associated with substance use in a large population sample: A cross-sectional study	11
The importance of pH: How aquarium water is affecting behavioural responses to drug exposure in larval zebrafish	11
Stress, inflammation, microbiome and depression	10
Untapped endocannabinoid pharmacological targets: Pipe dream or pipeline?	10
Blockade of kappa-opioid receptors amplifies microglia-mediated inflammatory responses	10
Nicotine-free vapor inhalation produces behavioral disruptions and anxiety-like behaviors in mice: Effects of puff duration, session length, sex, and flavor	10
The neurobiology of abstinence-induced reward-seeking in males and females	10
Sex differences in the rodent hippocampal opioid system following stress and oxycodone associated learning processes	10
Magnetic resonance spectroscopy studies of substance use disorders: Current landscape and potential future directions	10
NPY-Y1 receptors in dorsal periaqueductal gray modulate anxiety, alcohol intake, and relapse in Wistar rats	10
Neurobehavioral effects of environmental enrichment and drug abuse vulnerability: An updated review	10
Prophylactic effects of arketamine, but not hallucinogenic psychedelic DOI nor non-hallucinogenic psychedelic analog lisuride, in lipopolysaccharide-treated mice and mice exposed to chronic restrain s	9
Acquisition of remifentanil self-administration: Enhanced in female rats but no effect of adolescent stress exposure	9
The multimodal serotonin compound Vilazodone alone, but not combined with the glutamate antagonist Amantadine, reduces l-DOPA-induced dyskinesia in hemiparkinsonian rats	9
Chronic lithium exposure attenuates ketamine-induced mania-like behavior and c-Fos expression in the forebrain of mice	9
AMPed-up adolescents: The role of age in the abuse of amphetamines and its consequences on cognition and prefrontal cortex development	9
Multiomic biological approaches to the study of child abuse and neglect	9
Swimming exercise reduces the vulnerability to stress and contributes to the AKT/GSK3β/CRMP2 pathway and microtubule dynamics mediated protective effects on neuroplasticity in male C57BL/6 mice	9
Suvorexant maintenance enhances the reinforcing but not subjective and physiological effects of intravenous cocaine in humans	9
Temporary inactivation of the infralimbic cortex impairs while the blockade of its dopamine D2 receptors enhances auditory fear extinction in rats	9
Bupropion monotherapy alters neurotrophic and inflammatory markers in patients of major depressive disorder	9
Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system	9
Voluntary exercise as a treatment for incubated and expanded drug craving leading to relapse to addiction: Animal models	9
Microinjection of the BDNF receptor antagonist ANA-12 into the nucleus accumbens and medial-prefrontal cortex attenuates morphine-induced reward memory, and alterations of BDNF levels and apoptotic ce	9
Deletion of VGLUT2 in midbrain dopamine neurons attenuates dopamine and glutamate responses to methamphetamine in mice	9
Naloxone-induced conditioned place aversion score and extinction period are higher in C57BL/6J morphine-dependent mice than in Swiss: Role of HPA axis	9
mRNA and miRNA profiles in the nucleus accumbens are associated with psychological stress-induced susceptible and resilient mice	8
Sex differences in the impact of pain, morphine administration and morphine withdrawal on quality of life in rats	8
Acute ethanol administration produces larger spatial and nonspatial memory impairments in 29–33 month old rats compared to adult and 18–24 month old rats	8
Environmental enrichment and intranasal oxytocin administration reverse maternal separation-induced impairments of prosocial choice behavior	8
Contrasting effects of d-amphetamine and atomoxetine on measures of impulsive action and choice	8
A systematic review of cannabidiol trials in neurodevelopmental disorders	8
Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of Down syndrome: Effects of pharmacological targeting on behavioral phenotypes	8
Nicotine addiction: Translational insights from circuit neuroscience	8
Modern approaches to the development of synthetic cannabinoid receptor probes	8
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype	8
The non-selective adenosine antagonist theophylline reverses the effects of dopamine antagonism on tremor, motor activity and effort-based decision-making	8
Nicotine and the developing brain: Insights from preclinical models	8
Taurine modulates behavioral effects of intermittent ethanol exposure without changing brain monoamine oxidase activity in zebrafish: Attenuation of shoal- and anxiety-like responses, and abolishment	8
Substance use disorders and social determinants of health from electronic medical records obtained during Kentucky's “triple wave”	8
Synergistic antidepressant effects of citalopram and SB-334867 in the REM sleep-deprived mice: Possible role of BDNF	8
Concurrent measures of impulsive action and choice are partially related and differentially modulated by dopamine D1- and D2-like receptors in a rat model of impulsivity	8
Protein kinases in natural versus drug reward	8
Nicotine chronic tolerance development and withdrawal in the planaria (Schmidtea mediterranea)	7
Role of interaction of mGlu2 and 5-HT2A receptors in antipsychotic effects	7
CXCR2 antagonist SB332235 mitigates deficits in social behavior and dysregulation of Th1/Th22 and T regulatory cell-related transcription factor signaling in male BTBR T+ Itpr3tf/J mouse model of auti	7
Accelerated habitual learning resulting from L-dopa exposure in rats is prevented by N-acetylcysteine	7
Attachment anxiety moderates the effect of oxytocin on negative emotion recognition: Evidence from eye-movement data	7
Male, but not female, Sprague Dawley rats display enhanced fear learning following acute ethanol withdrawal (hangover)	7
Behavioral and pharmacological interventions for the prevention and treatment of psychiatric disorders with children exposed to maltreatment	7
A social contextual review of the effects of alcohol on emotion	7
The importance of examining sex differences in animal models validated to induce an addiction-like phenotype	7
Exercise intervention for preventing risperidone-induced dyslipidemia and gluco-metabolic disorders in female juvenile rats	7
Chronic rapid eye movement sleep restriction during juvenility has long-term effects on anxiety-like behaviour and neurotransmission of male Wistar rats	7
Metabotropic glutamate receptor 3 as a potential therapeutic target for psychiatric and neurological disorders	7
Single cannabidiol administration affects anxiety-, obsessive compulsive-, object memory-, and attention-like behaviors in mice in a sex and concentration dependent manner	7
Enhanced antidepressant-like effects of a delta opioid receptor agonist, SNC80, in rats under inflammatory pain	7
Age-dependent effects of embryonic ethanol exposure on anxiety-like behaviours in young zebrafish: A genotype comparison study	7