Kidney International

Article	Citations
In This Issue	4025
Table of Contents	1134
Subscription Information	615
Taking the A(llorecognition) train: connecting passenger T cells to DSA	425
in this issue	359
Thirsty encounters of the third kind	338
Misuse of the Cox proportional hazards model and alternative approaches in kidney outcome research	324
Title Page	289
Editorial Board	253
Editorial Board	207
Including APOL1 alleles and ancestry adjustments improve a genome-wide polygenic CKD score	195
Function follows form: the quest for the best prognostic imaging biomarker in ADPKD	185
Unexpected metabolic effects of sodium-glucose cotransporter 2 inhibitors	146
Seeing through the density of dense deposit disease	144
Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner	133
Improving frozen section evaluation of procurement donor kidney biopsies and reducing the discard rate: a promising role for artificial intelligence	131
Gene editing: a near future for the treatment of genetic kidney diseases	127
Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality	127
Identification of the gut microbial enzyme turning the urine yellow	122
Challenges in the development of novel methodologies for measuring glomerular filtration rate	120
Proximal-tubule molecular relay from early Protein diaphanous homolog 1 to late Rho-associated protein kinase 1 regulates kidney function in obesity-induced kidney damage	119
Autoimmunoglobulin-triggered extracellular vesicles as new players in membranous nephropathy: friends or foes?	116
A pig kidney supporting human physiology	114
Enhancing kidney organoid maturity with inducible vascularization: another step forward for in vitro modeling	112
Giving monocytes their due: how CD47–SIRP-α reframes allograft rejection	111

The authors reply:	110
Editorial Board	109
The Case | Progressive submandibular mass and nephrotic syndrome in a young man	104
Podocyte-derived endothelin-1 and endothelial cell endothelin A receptors are essential for glomerular injury in mouse models of focal segmental glomerulosclerosis	95
Unlocking the full potential of human pluripotent stem cell–derived kidney organoids through bioengineering	94
Rationale and design of the Nephrotic Syndrome Study Network (NEPTUNE) Match in glomerular diseases: designing the right trial for the right patient, today	90
A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease	89
New advances in endocrine hypertension: from genes to biomarkers	88
Endothelial but not systemic ferroptosis inhibition protects from antineutrophil cytoplasmic antibody–induced crescentic glomerulonephritis	88
IL-33 as a component of neutrophil extracellular traps mediates contrast-induced acute kidney injury by promoting ferroptosis in tubular epithelial cells	85
On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome	84
Kidney supportive care: every nephrologist’s business	84
Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury	80
Executive Summary of the KDIGO 2026 Clinical Practice Guideline for the Management of Anemia in Chronic Kidney Disease (CKD)	79
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function	79
Glomerular-tubular crosstalk via cold shock Y-box binding protein-1 in the kidney	77
Women and kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference	76
Monoclonal immunoglobulin crystalline nephropathies	72
Epigenetic alterations and memory: key players in the development/progression of chronic kidney disease promoted by acute kidney injury and diabetes	70
Kidney protective mechanisms of SGLT2 inhibitors: evidence for a hemodynamic effect	69
The single-cell landscape of the human vein after arteriovenous fistula creation and implications for maturation failure	68
Role of Erythroid Fibroblast Growth Factor 23 in regulating erythropoiesis	68
Blood pressure adaptation in vertebrates: comparative biology	67
Kidney transplantation and hyperbaric oxygen treatment for calciphylaxis	65
Felzartamab: a magic bullet to treat microvascular rejection?	65
Expanding the perspective: addressing additional limitations in cardiovascular risk assessment of immunosuppressive therapies	65
Editorial Board	64
Improving the management of chronic kidney disease in primary care by enhancing laboratory reports with additional information and follow-up procedures	63
Erdheim-Chester disease: hairy kidney and coated aorta	63
The T-cell environment: may the regulatory force be with you	62
Impact of study design on vaccine effectiveness estimates of 2 mRNA COVID-19 vaccine doses in patients with stage 5 chronic kidney disease	61
RORing toward immunoregulation in glomerulonephritis?	61
Response to the commentary “Modeling pulse wave velocity trajectories—challenges, opportunities, and pitfalls”	61
Letter to the Editor	61
Editorial Board	61
Subscription Information	58
journal club	58
The Case | Is this hemolytic uremic syndrome?	58
The Case | A patient with skin rash, monoclonal gammopathy, and proteinuria	57
Acknowledgment of reviewers	57
The authors reply	57
Renal artery microaneurysms in antineutrophil cytoplasmic antibody–associated vasculitis	56
The authors reply:	55
First do no harm: systemic glucocorticoids should not be used for the treatment of progressive IgA nephropathy	54
Kidney health without borders: a multilingual kidney education platform	54
Techniques to predict survival outcomes in nephrology: basics and traditional methods	54
Seeing the light (chains): a paradigm shift in PGNMID	54
Urine: from waste to fertilizer	53
Cinacalcet in focal segmental glomerular sclerosis: a case report	52
Corrigendum to “Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Management of ANCA–Associated Vasculitis.” Kidney International 2024;105(3):447–449	52

in this issue	52
Corrigendum to “Effects of dialysate potassium concentration of 3.0 mmol/l with sodium zirconium cyclosilicate on dialysis-free days versus dialysate potassium concentration of 2.0 mmol/l alone on rat	52
Table of Contents	51
Caution in interpreting anti-nephrin antibodies as causal in nephrotic syndrome	51
The Case | A patient with autosomal dominant polycystic kidney disease with an atypical kidney magnetic resonance image	51
The Case | Neonatal seizures and tubular dysfunction in childhood: joining the dots!	50
Sexual dimorphism of age and nephron segment specific gene expression in mouse kidneys: insights from multi-omic and spatial analysis	49
Mitochondrial ROS connects P2X7-mediated Ca2+ influx with IL-1α release by monocytes upon chronic tissue damage	49
A genomic deep field view of hypertension	49
Identifying strategies for disseminating research to patients with chronic kidney disease and caregivers: a workshop report	49
The transcription factor ATF4 mediates endoplasmic reticulum stress-related podocyte injury and slit diaphragm defects	48
Protein kinase ROCK1 activates mitochondrial fission linking to oxidative stress and muscle atrophy	48
To do or not to do—genetic testing for autosomal dominant polycystic kidney disease in children and adolescents	47
Bilateral renal fungal balls in a premature infant	47
The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis	46
Cadherin-11 mediates kidney injury through altered renal fibroblast mechanobiology	46
Repression of peroxisome proliferation-activated receptor γ coactivator-1α by p53 after kidney injury promotes mitochondrial damage and maladaptive kidney repair	46
Tumor-induced osteomalacia	46
Optimizing symptom management in people with kidney failure	46
Machine learning does not outperform traditional statistical modelling for kidney allograft failure prediction	45
Kidney-resident macrophages limit toxin-induced inflammation through their hallmark functions	45
Age and memory B cells at baseline are associated with risk of relapse and memory B-cell reappearance following anti-CD20 treatment in pediatric frequently-relapsing/steroid-dependent nephrotic syndro	44
Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model	44
Hypoxia hits APOL1 in the kidney	44
Dynamically visualizing profibrotic maladaptive repair after acute kidney injury by fibroblast activation protein imaging	43
Phenotype first: a data-driven approach to genetic penetrance	43
Complement activation and effector pathways in membranous nephropathy	43
journal club	42
Renal Pathology Society/International Kidney and Monoclonal Gammopathy Research Group consensus on pathologic definitions and terminology of monoclonal gammopathy–associated kidney lesions	42
The authors reply	42
The prevention and management of chronic kidney disease among patients with metabolic syndrome	42
Subscription Information	42
Editorial Board	42
Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma	42
Title Page	42
Deciphering missense coding variants with AlphaMissense	41
Cutaneous histoplasmosis in a patient with a kidney transplant	41
Molecular profiling of kidney compartments from serial biopsies differentiate treatment responders from non-responders in lupus nephritis	41
The nucleotide-sensing Toll-Like Receptor 9/Toll-Like Receptor 7 system is a potential therapeutic target for IgA nephropathy	41
in this issue	40
Subscription Information	40
Do macrophages inhibit or promote atheroma plaque calcification and stability?	40
Subscription Information	40
Subscription Information	40
Discrepancies between transcutaneous and estimated glomerular filtration rates in rats	40
Table of Contents	40
Fragmented futures: ROCK1 drives mitochondrial fission and muscle loss in CKD	39
Peripheral blood smear as a diagnostic clue to type I cryoglobulinemia	38
The Case | Acute kidney injury and a facial lesion	38
Integrating basic science with translational research: the 13th International Podocyte Conference 2021	38
Table of Contents	38
Editorial Board	37
High-dimensional mass cytometry identified circulating natural killer T-cell subsets associated with protection from cytomegalovirus infection in kidney transplant recipients	36
Kidney biopsy in acute kidney injury: increase insight or preserve the status quo?	36
Effective management of chyluria with retrograde thoracic duct catheterization and embolization	36
Advancing proteomics in nephrology: unraveling causal pathways and therapeutic targets	36
Good and evil, more reasons to study UPR	36
The authors reply	36
Anti-nephrin autoantibodies: novel predictors of post-transplant recurrence of focal segmental glomerular sclerosis	36
Lineage tracing analysis defines erythropoietin-producing cells as a distinct subpopulation of resident fibroblasts with unique behaviors	36
Berger disease redux	35
Enhancer and super-enhancer landscape in polycystic kidney disease	35
Strategies for the development of sodium-glucose cotransporter-2 inhibitors for kidney protection in pediatric chronic kidney disease: proceedings of a workshop meeting in July 2023	35
Cardiovascular disease as a risk factor for frailty in dialysis patients	35
When YAP is hyperactivated in podocytes, it persistently “yaps,” disrupting the quiescence of neighboring glomerular cells	35
Dried blood spot testing versus standard i.v. sampling for GFR measurement with iohexol or 99mTc-DTPA	35
Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events	35
A paired-kidney allocation study found superior survival with HLA-DR compatible kidney transplants in the Eurotransplant Senior Program	34
Risk stratification of metabolic disorder–associated kidney disease	34
Apixaban for stroke prevention in hemodialysis patients with nonvalvular atrial fibrillation	34
Kidney cancer screening: novel concepts beyond population-level screening	34
Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis	34
Female sex hormones inversely regulate acute kidney disease susceptibility throughout life	34
Endothelial prolyl hydroxylase 3 mitigates maladaptive inflammation to promote post-ischemic kidney repair	34
Endemic rise in cases of acute kidney injury in children in Indonesia and Gambia: what is the likely culprit and why?	33
Sex-specific shifts in CKD classification using European Kidney Function Consortium (EKFC) as compared to CKD Epidemiology (CKD-EPI) eGFR equations	33
in this issue	33
Insulin-like growth factor binding protein 7 promotes acute kidney injury by alleviating poly ADP ribose polymerase 1 degradation	33
Implementing the commitments of the WHO kidney health resolution: initial steps in 3 diverse settings	33
Empagliflozin-associated Armanni-Ebstein lesions in IgA nephropathy	33

The Case | Podocyte vacuolization and myelin figures in a young male with proteinuria	33
From the field to the assembly hall: the history of the kidney health resolution	33
Critical Role of histone deacetylase 3 in the regulation of kidney inflammation and fibrosis	32
Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression	32
Estimating glomerular filtration rate from serum creatinine concentration in children with augmented renal clearance: all formulas are equivocal, but some are more equivocal than others	32
Role of the kidney in glucose homeostasis: the basis for pharmacotherapy and prevention of cardiorenal complications in diabetes	32
A pragmatic, open-label, randomized controlled trial of Plasma-Lyte-148 versus standard intravenous fluids in children receiving kidney transplants (PLUTO)	32
The authors reply	31
Asymptomatic migration of a peritoneal dialysis catheter	31
Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease: known knowns and known unknowns	31
In this Issue	31
Table of Contents	31
ER stress and slit diaphragms: is there a connection?	31
in this issue	31
Subscription Information	31
Editorial Board	30
Table of Contents	30
Subscription Information	30
The Case | Acute neck swelling in a patient undergoing dialysis	30
in this issue	30
journal club	30
Series introduction: drug repurposing for kidney diseases	30
The authors reply	29
Acquired cutis laxa from heavy chain deposition disease	29
Leukocyte immunoglobulin like receptor B3 (LILRB3) and allograft survival: can precision medicine target health disparities?	29
Is bone histomorphometry required for assessment of renal osteodystrophy in clinical practice?	29
The authors reply	29
Has APOL1 kidney disease treatment been hiding in plain sight?	29
The Case | An unusual cause of proteinuria in a kidney transplant recipient	29
Antioxidant nanozymes for prevention of diseased kidney from failure	29
Myeloid-derived growth factor deficiency exacerbates mitotic catastrophe of podocytes in glomerular disease	28
Unfolding the potential—chemical chaperones in Alport syndrome	28
RNA methylation in acute kidney injury: opening up new therapeutic avenues	28
An introduction to realist evaluation and synthesis for kidney research	28
Uremia-associated fibrinous pericarditis	28
Using prediction models to improve care and communicate risk: updated modeling for children with IgA nephropathy	28
CCL2 as a microvascular “tone breaker”: inflammatory signaling and the failure of kidney autoregulation in salt-sensitive hypertension	27
Table of Contents	27
Reevaluating principal component analysis: advocating for nonlinear and nonparametric methods in multi-omics data analysis	27
In remembrance of Gary Striker, MD (1934–2024)	27
Kidney targeting of formoterol containing polymeric nanoparticles improves recovery from ischemia reperfusion-induced acute kidney injury in mice	27
A genetically inducible endothelial niche enables vascularization of human kidney organoids with multilineage maturation and emergence of renin expressing cells	27
Mendelian randomization for nephrologists	27
A multiomic resource to interpret genetic associations with kidney function	27
The authors reply:	27
Glomerular filtration rate estimation in transgender and gender-diverse adults using gender-affirming hormone therapy: an exploratory cross-sectional study	27
in this issue	27
Equity in evidence: overcoming barriers to kidney trials in low-resource settings	27
The Case | Dark dialysate after colonoscopy	27
Progress, challenges, and pragmatic concessions in predicting relative risk of kidney survival in ARPKD	27
Table of Contents	27
A national registry study evaluated the landscape of kidney transplantation among presumed unauthorized immigrants in the United States	26
Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis	26
Conservative kidney management and kidney supportive care: core components of integrated care for people with kidney failure	26
Table of Contents	26
A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease	26
Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2	26
The authors reply:	26
in this issue	26
Anti-nephrin antibodies guide living donor kidney transplantation in a pediatric patient with primary focal segmental glomerular sclerosis	26
Are your kidneys Ok? Detect early to protect kidney health	26
Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children	26
KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary	26
In memoriam: George L. Bakris, MD, 1952–2024	25
Unique problems for the design of the first trials of transplanting porcine kidneys into humans	25
Avoiding arrythmias by personalizing the dialysate concentration: a case for precision medicine in patients on dialysis	25
Bile cast nephropathy after sinusoidal obstruction syndrome	25
Subscription Information	25
Probing the surrogate validity of proteinuria thresholds in C3 glomerulopathy/immune-complex membranoproliferative glomerulonephritis: unresolved biases and mechanistic gaps	25
Title Page	25
Preventing MMP23-mediated cleavage of podocyte RARRES1: a novel strategy to halt chronic kidney disease progression?	25
Editorial Board	25
IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury	24
Editorial Board	24
Insights from ADPedKD, ERKReg and RaDaR registries provide a multi-national perspective on the presentation of childhood autosomal dominant polycystic kidney disease in high- and middle-income countri	24
The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis	24
in this issue	24
journal club	24
in this issue	24
Results of the EPISODE trial plead for reasonable practice-based serum phosphate lowering in patients on dialysis	24
Targeting angiopoietin-2 as a novel treatment option for kidney fibrosis	24
Subscription Information	24
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy	23
Paraspeckle protein NONO attenuates vascular calcification by inhibiting bone morphogenetic protein 2 transcription	23
Multi-stain deep learning prediction model of treatment response in lupus nephritis based on renal histopathology	23
Myeloperoxidase-ANCA IgG induces different forms of small vessel vasculitis based on type of synergistic immune stimuli	23
Nephronophthisis-associated ciliopathy with brachydactyly, medullary cysts, and chronic kidney disease	23
Cilastatin, a new therapeutic promise for acute kidney injury	23
Melanocortin 5 receptor signaling protects against podocyte injury in proteinuric glomerulopathies	23
A reliable clinical test for detection of membranous nephropathy antigens using laser microdissection and mass spectrometry	23
In memoriam: Lise Bankir (1942–2026)	23
E-prostanoid 3 receptor deficiency on myeloid cells protects against ischemic acute kidney injury via breaking the auto-amplification loop of necroinflammation	23
Phospholipase A2 receptor-positive membranous nephropathy detected by laser microdissection and mass spectrometry in patients negative by immunofluorescence for phospholipase A2 receptor on kidney bio	23
METTL3-targeted intervention on nuclear factors RORA/RORγt suppresses pathogenic T helper 17 cell differentiation and alleviates kidney damage in lupus nephritis	23
Stronger together: the power of cross-organ data sets for improved allograft study outcomes	23