Kidney International

Article	Citations
Challenges in the development of novel methodologies for measuring glomerular filtration rate	1919
In This Issue	785
Table of Contents	415
Subscription Information	260
Taking the A(llorecognition) train: connecting passenger T cells to DSA	223
in this issue	215
Thirsty encounters of the third kind	213
Misuse of the Cox proportional hazards model and alternative approaches in kidney outcome research	199
Identification of the gut microbial enzyme turning the urine yellow	167
Monoclonal immunoglobulin crystalline nephropathies	159
A pig kidney supporting human physiology	151
Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner	145
New advances in endocrine hypertension: from genes to biomarkers	143
Function follows form: the quest for the best prognostic imaging biomarker in ADPKD	136
Gene editing: a near future for the treatment of genetic kidney diseases	132
Endothelial but not systemic ferroptosis inhibition protects from antineutrophil cytoplasmic antibody–induced crescentic glomerulonephritis	126
On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome	121
Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study	115
Title Page	111
Blood pressure adaptation in vertebrates: comparative biology	110
Proximal-tubule molecular relay from early Protein diaphanous homolog 1 to late Rho-associated protein kinase 1 regulates kidney function in obesity-induced kidney damage	90
Editorial Board	88
Editorial Board	87
Journal Club	87
Glomerular-tubular crosstalk via cold shock Y-box binding protein-1 in the kidney	86

Including APOL1 alleles and ancestry adjustments improve a genome-wide polygenic CKD score	85
Subscription Information	85
A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease	84
Editorial Board	84
In this issue	84
Should we consider calcimimetics as a therapeutic option for nephrotic syndrome?	83
Kidney supportive care: every nephrologist’s business	82
Unexpected metabolic effects of sodium-glucose cotransporter 2 inhibitors	80
Enhancing kidney organoid maturity with inducible vascularization: another step forward for in vitro modeling	78
Seeing through the density of dense deposit disease	78
Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality	77
Epigenetic alterations and memory: key players in the development/progression of chronic kidney disease promoted by acute kidney injury and diabetes	76
Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes	75
Improving frozen section evaluation of procurement donor kidney biopsies and reducing the discard rate: a promising role for artificial intelligence	74
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function	73
The single-cell landscape of the human vein after arteriovenous fistula creation and implications for maturation failure	73
Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury	71
Rationale and design of the Nephrotic Syndrome Study Network (NEPTUNE) Match in glomerular diseases: designing the right trial for the right patient, today	70
Kidney protective mechanisms of SGLT2 inhibitors: evidence for a hemodynamic effect	69
Women and kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference	67
Antibody and T-cell response to a third dose of SARS-CoV-2 mRNA BNT162b2 vaccine in kidney transplant recipients	67
Unlocking the full potential of human pluripotent stem cell–derived kidney organoids through bioengineering	66
Identifying strategies for disseminating research to patients with chronic kidney disease and caregivers: a workshop report	65
Sexual dimorphism of age and nephron segment specific gene expression in mouse kidneys: insights from multi-omic and spatial analysis	65
Expanding the perspective: addressing additional limitations in cardiovascular risk assessment of immunosuppressive therapies	64
Corrigendum to “Effects of dialysate potassium concentration of 3.0 mmol/l with sodium zirconium cyclosilicate on dialysis-free days versus dialysate potassium concentration of 2.0 mmol/l alone on rat	62
Kidney transplantation and hyperbaric oxygen treatment for calciphylaxis	60
Corrigendum to “Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Management of ANCA–Associated Vasculitis.” Kidney International 2024;105(3):447–449	59
To do or not to do—genetic testing for autosomal dominant polycystic kidney disease in children and adolescents	59
The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis	57
Editorial Board	57
Mitochondrial ROS connects P2X7-mediated Ca2+ influx with IL-1α release by monocytes upon chronic tissue damage	57
Protein kinase ROCK1 activates mitochondrial fission linking to oxidative stress and muscle atrophy	57
Erdheim-Chester disease: hairy kidney and coated aorta	56
Improving the management of chronic kidney disease in primary care by enhancing laboratory reports with additional information and follow-up procedures	55
Acknowledgment of reviewers	54
Renal Pathology Society/International Kidney and Monoclonal Gammopathy Research Group consensus on pathologic definitions and terminology of monoclonal gammopathy–associated kidney lesions	54
Renal artery microaneurysms in antineutrophil cytoplasmic antibody–associated vasculitis	54
Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model	53
Caution in interpreting anti-nephrin antibodies as causal in nephrotic syndrome	53
Optimizing symptom management in people with kidney failure	53
The transcription factor ATF4 mediates endoplasmic reticulum stress-related podocyte injury and slit diaphragm defects	53
The authors reply:	53
The T-cell environment: may the regulatory force be with you	52
Kidney-resident macrophages limit toxin-induced inflammation through their hallmark functions	52
Kidney traits on repeat—the role of MUC1 VNTR	51
Letter to the Editor	51
Urine: from waste to fertilizer	51
Crystal-induced colitis	50
in this issue	50

Editorial Board	49
In This Issue	49
Immunoaging within the kidney via injury-associated tertiary lymphoid tissue	48
RORing toward immunoregulation in glomerulonephritis?	47
Editorial Board	47
A genomic deep field view of hypertension	46
Subscription Information	46
Response to the commentary “Modeling pulse wave velocity trajectories—challenges, opportunities, and pitfalls”	46
Erratum to Kudose S, Lipton M, Jain NG, D’Agati VD. “Valproic acid–associated proximal tubulopathy.” Kidney Int. 2022;101:653	46
The authors reply	46
Tumor-induced osteomalacia	45
Impact of study design on vaccine effectiveness estimates of 2 mRNA COVID-19 vaccine doses in patients with stage 5 chronic kidney disease	44
journal club	44
Unexpected cause of vemurafenib-induced nephrotoxicity: ferrochelatase	44
Subscription Information	44
The Case | A patient with skin rash, monoclonal gammopathy, and proteinuria	43
The Case | Is this hemolytic uremic syndrome?	43
The Case | A patient with autosomal dominant polycystic kidney disease with an atypical kidney magnetic resonance image	42
Hypoxia hits APOL1 in the kidney	42
The authors reply	42
The Case | Neonatal seizures and tubular dysfunction in childhood: joining the dots!	42
The prevention and management of chronic kidney disease among patients with metabolic syndrome	42
Cinacalcet in focal segmental glomerular sclerosis: a case report	42
Felzartamab: a magic bullet to treat microvascular rejection?	42
Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma	42
Complement activation and effector pathways in membranous nephropathy	41
Dynamically visualizing profibrotic maladaptive repair after acute kidney injury by fibroblast activation protein imaging	41
Machine learning does not outperform traditional statistical modelling for kidney allograft failure prediction	41
Title Page	40
Repression of peroxisome proliferation-activated receptor γ coactivator-1α by p53 after kidney injury promotes mitochondrial damage and maladaptive kidney repair	40
First do no harm: systemic glucocorticoids should not be used for the treatment of progressive IgA nephropathy	40
Age and memory B cells at baseline are associated with risk of relapse and memory B-cell reappearance following anti-CD20 treatment in pediatric frequently-relapsing/steroid-dependent nephrotic syndro	40
Discrepancies between transcutaneous and estimated glomerular filtration rates in rats	39
The authors reply	38
Cardiovascular disease as a risk factor for frailty in dialysis patients	38
Editorial Board	38
Cutaneous histoplasmosis in a patient with a kidney transplant	37
journal club	37
High-dimensional mass cytometry identified circulating natural killer T-cell subsets associated with protection from cytomegalovirus infection in kidney transplant recipients	37
Risk stratification of metabolic disorder–associated kidney disease	37
The Case | Acute kidney injury and a facial lesion	36
Subscription Information	36
Do macrophages inhibit or promote atheroma plaque calcification and stability?	36
Modeling pulse wave velocity trajectories—challenges, opportunities, and pitfalls	36
The authors reply:	36
Expression of concern from the KI Editors: “Apolipoprotein-1 risk variants and associated kidney phenotypes in an adult HIV cohort in Nigeria” [Kidney International, July 2021, Pages 146–154] and “APO	36
Fragmented futures: ROCK1 drives mitochondrial fission and muscle loss in CKD	36
in this issue	36
Table of Contents	36
Initiation of maintenance dialysis: back to the future	35
A pragmatic, open-label, randomized controlled trial of Plasma-Lyte-148 versus standard intravenous fluids in children receiving kidney transplants (PLUTO)	35
The relationship between imaging features of diffusion-weighted imaging and prognosis of chronic kidney disease	35
Editorial Board	35
Molecular profiling of kidney compartments from serial biopsies differentiate treatment responders from non-responders in lupus nephritis	34
Integrating basic science with translational research: the 13th International Podocyte Conference 2021	34
A paired-kidney allocation study found superior survival with HLA-DR compatible kidney transplants in the Eurotransplant Senior Program	34
Estimating glomerular filtration rate from serum creatinine concentration in children with augmented renal clearance: all formulas are equivocal, but some are more equivocal than others	34
Table of Contents	33
Kidney biopsy in acute kidney injury: increase insight or preserve the status quo?	33
Deciphering missense coding variants with AlphaMissense	33
Subscription Information	33
Dried blood spot testing versus standard i.v. sampling for GFR measurement with iohexol or 99mTc-DTPA	33
Findings from 4C-T Study demonstrate an increased cardiovascular burden in girls with end stage kidney disease and kidney transplantation	32
Contactin-1–associated membranous nephropathy: complete immunologic and clinical remission with rituximab	32
Anti-nephrin autoantibodies: novel predictors of post-transplant recurrence of focal segmental glomerular sclerosis	32
Subscription Information	32
Editorial Board	31
Strategies for the development of sodium-glucose cotransporter-2 inhibitors for kidney protection in pediatric chronic kidney disease: proceedings of a workshop meeting in July 2023	31
Table of Contents	31
Good and evil, more reasons to study UPR	31
Advancing proteomics in nephrology: unraveling causal pathways and therapeutic targets	30
Lineage tracing analysis defines erythropoietin-producing cells as a distinct subpopulation of resident fibroblasts with unique behaviors	30
Effective management of chyluria with retrograde thoracic duct catheterization and embolization	30
Female sex hormones inversely regulate acute kidney disease susceptibility throughout life	30
Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression	30
The authors reply	30
Peripheral blood smear as a diagnostic clue to type I cryoglobulinemia	30
Enhancer and super-enhancer landscape in polycystic kidney disease	29
Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events	29
The nucleotide-sensing Toll-Like Receptor 9/Toll-Like Receptor 7 system is a potential therapeutic target for IgA nephropathy	29

The lupus nephritis management renaissance	29
Critical Role of histone deacetylase 3 in the regulation of kidney inflammation and fibrosis	29
Apixaban for stroke prevention in hemodialysis patients with nonvalvular atrial fibrillation	29
Insulin-like growth factor binding protein 7 promotes acute kidney injury by alleviating poly ADP ribose polymerase 1 degradation	29
Role of proteinuria in the anemia of chronic kidney disease	29
The authors reply	28
Endemic rise in cases of acute kidney injury in children in Indonesia and Gambia: what is the likely culprit and why?	28
In this Issue	28
A national registry study evaluated the landscape of kidney transplantation among presumed unauthorized immigrants in the United States	28
Subscription Information	28
New-onset class III lupus nephritis with multi-organ involvement after COVID-19 vaccination	28
Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease: known knowns and known unknowns	28
National and international kidney failure registries: characteristics, commonalities, and contrasts	28
Table of Contents	28
Has APOL1 kidney disease treatment been hiding in plain sight?	28
Loss of proximal tubular transcription factor Krüppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation	28
ER stress and slit diaphragms: is there a connection?	28
Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2	28
Anti-nephrin antibodies guide living donor kidney transplantation in a pediatric patient with primary focal segmental glomerular sclerosis	28
in this issue	27
Asymptomatic migration of a peritoneal dialysis catheter	27
The authors reply	27
Using prediction models to improve care and communicate risk: updated modeling for children with IgA nephropathy	27
Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children	27
Progress, challenges, and pragmatic concessions in predicting relative risk of kidney survival in ARPKD	27
An introduction to realist evaluation and synthesis for kidney research	27
In remembrance of Gary Striker, MD (1934–2024)	27
The Case | Acute neck swelling in a patient undergoing dialysis	26
The authors reply:	26
Protective mechanisms harnessing against injurious heme and preventing kidney damage in STEC-HUS: toward new therapies?	26
Table of Contents	26
Subscription Information	26
Editorial Board	26
Reevaluating principal component analysis: advocating for nonlinear and nonparametric methods in multi-omics data analysis	26
A novel model of nephrotic syndrome results from a point mutation in Lama5 and is modified by genetic background	26
journal club	26
Is bone histomorphometry required for assessment of renal osteodystrophy in clinical practice?	25
Antioxidant nanozymes for prevention of diseased kidney from failure	25
The Case | Dark dialysate after colonoscopy	25
The Case | An unusual cause of proteinuria in a kidney transplant recipient	25
Acquired cutis laxa from heavy chain deposition disease	25
Valproic acid–associated proximal tubulopathy	25
in this issue	25
The authors reply	25
Subscription Information	25
Unfolding the potential—chemical chaperones in Alport syndrome	24
Kidney targeting of formoterol containing polymeric nanoparticles improves recovery from ischemia reperfusion-induced acute kidney injury in mice	24
Myeloid-derived growth factor deficiency exacerbates mitotic catastrophe of podocytes in glomerular disease	24
Uremia-associated fibrinous pericarditis	24
Mendelian randomization for nephrologists	24
A multiomic resource to interpret genetic associations with kidney function	24
A genetically inducible endothelial niche enables vascularization of human kidney organoids with multilineage maturation and emergence of renin expressing cells	24
Series introduction: drug repurposing for kidney diseases	24
Leukocyte immunoglobulin like receptor B3 (LILRB3) and allograft survival: can precision medicine target health disparities?	24
Glomerular filtration rate estimation in transgender and gender-diverse adults using gender-affirming hormone therapy: an exploratory cross-sectional study	24
Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis	24
The authors reply:	24
Conservative kidney management and kidney supportive care: core components of integrated care for people with kidney failure	24
Are your kidneys Ok? Detect early to protect kidney health	24
A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease	24
How cyclosporine reduces mycophenolic acid exposure by 40% while other calcineurin inhibitors do not	23
Kidney toxicity of phosphate: is that crystal clear yet?	23
Preventing MMP23-mediated cleavage of podocyte RARRES1: a novel strategy to halt chronic kidney disease progression?	23
KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary	23
Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis	23
Title Page	23
in this issue	23
Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier	23
Table of Contents	23
In memoriam: George L. Bakris, MD, 1952–2024	23
A multiple 24-hour urine collection study indicates that kidney function decline is related to urinary sodium and potassium excretion in patients with chronic kidney disease	22
Nephronophthisis-associated ciliopathy with brachydactyly, medullary cysts, and chronic kidney disease	22
Editorial Board	22
Bile cast nephropathy after sinusoidal obstruction syndrome	22
Windswept deformity of lower limbs in a patient with end-stage renal disease and rickets	22
journal club	22
Corrigendum to Cai J, Liu Z, Huang X, et al. The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking β-catenin target gene expression Kidney Int. 2020;97:106–118	22
Advanced optical imaging reveals preferred spatial orientation of podocyte processes along the axis of glomerular capillaries	22
Breakthrough omicron COVID-19 infections in patients receiving the REGEN-Cov antibody combination	22
IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury	22
Editorial Board	21
Doxorubicin-associated red-colored dialysate	21
Subscription Information	21
Preclinical evaluation of antigen-specific B-cell depletion for phospholipase A2 receptor membranous nephropathy with chimeric autoantibody receptor T-cells.	21
Multi-stain deep learning prediction model of treatment response in lupus nephritis based on renal histopathology	21
Recognizing the true face of noninfectious cryoglobulinemic glomerulonephritis	21
Avoiding arrythmias by personalizing the dialysate concentration: a case for precision medicine in patients on dialysis	21
Phospholipase A2 receptor-positive membranous nephropathy detected by laser microdissection and mass spectrometry in patients negative by immunofluorescence for phospholipase A2 receptor on kidney bio	21
Suppression of aldehyde dehydrogenase 2 in kidney proximal tubules contributes to kidney fibrosis through Transforming Growth Factor-β signaling	21
A Mendelian randomization study found causal linkage between telomere attrition and chronic kidney disease	21
Subscription Information	21
The Case | A rare donor-derived cause of delayed graft function	21
Melanocortin 5 receptor signaling protects against podocyte injury in proteinuric glomerulopathies	21
Hemolysis is associated with altered heparan sulfate of the endothelial glycocalyx and with local complement activation in thrombotic microangiopathies	21
Renal AA amyloidosis: presentation, diagnosis, and current therapeutic options: a review	21