OOIR: Observatory of International Research

Papers

(The TQCC of Progress in Biophysics & Molecular Biology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies	72
In-silico human electro-mechanical ventricular modelling and simulation for drug-induced pro-arrhythmia and inotropic risk assessment	57
Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease	50
Bioelectrical approaches to cancer as a problem of the scaling of the cellular self	42
Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors	41
Compressed sensing in fluorescence microscopy	41
ROS-induced cell cycle arrest as a mechanism of resistance in polyaneuploid cancer cells (PACCs)	39
Removing striping artifacts in light-sheet fluorescence microscopy: a review	39
A free energy principle for generic quantum systems	38
Localized reconstruction in Scipion expedites the analysis of symmetry mismatches in cryo-EM data	35
Ih from synapses to networks: HCN channel functions and modulation in neurons	35
The multiple biological roles of the cholinesterases	33
Human coronavirus spike protein-host receptor recognition	32
Towards high-throughput in situ structural biology using electron cryotomography	32
Two-phased evolution: Genome chaos-mediated information creation and maintenance	29
An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines	29
Mesoscale microscopy and image analysis tools for understanding the brain	27
Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system	27
The role of stochasticity in biological communication processes	25
Curcumin and cancer; are long non-coding RNAs missing link?	25
A systematic review on machine learning and deep learning techniques in cancer survival prediction	23
What prevents mainstream evolutionists teaching the whole truth about how genomes evolve?	23
The murburn precepts for aerobic respiration and redox homeostasis	23
Roles of ATM and ATR in DNA double strand breaks and replication stress	21
Computational models of cardiac hypertrophy	21

Treasuring the computational approach in medicinal plant research	21
Tools for visualizing and analyzing Fourier space sampling in Cryo-EM	20
Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response	20
Beyond pacemaking: HCN channels in sinoatrial node function	20
Quantum information theoretic approach to the mind–brain problem	20
Xanthohumol: An underestimated, while potent and promising chemotherapeutic agent in cancer treatment	20
The gene: An appraisal	20
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease	20
Living systems approached from physical principles	19
The resolution revolution in X-ray diffraction, Cryo-EM and other Technologies	19
Biophysical analysis of an HCN1 epilepsy variant suggests a critical role for S5 helix Met-305 in voltage sensor to pore domain coupling	19
Advances in the understanding of protein misfolding and aggregation through molecular dynamics simulation	19
DNA replication stress and emerging prospects for PARG inhibitors in ovarian cancer therapy	18
Fanconi anemia-independent DNA inter-strand crosslink repair in eukaryotes	18
Cellular Darwinism: Regulatory networks, stochasticity, and selection in cancer development	17
In vitro cell stretching technology (IsoStretcher) as an approach to unravel Piezo1-mediated cardiac mechanotransduction	17
Identification and diagnosis of long COVID-19: A scoping review	17
The role of mechanosensitive Piezo1 channel in diseases	17
Biophysical mechanisms underlying the effects of static magnetic fields on biological systems	16
Further insights into the molecular complexity of the human sinus node – The role of ‘novel’ transcription factors and microRNAs	16
Different methods, techniques and their limitations in protein structure prediction: A review	16
Mathematical modelling of the mechano-electric coupling in the human cardiomyocyte electrically connected with fibroblasts	16
Inosine and its methyl derivatives: Occurrence, biogenesis, and function in RNA	16
New role of TRPM4 channel in the cardiac excitation-contraction coupling in response to physiological and pathological hypertrophy in mouse	16
Ca2+ currents in cardiomyocytes: How to improve interpretation of patch clamp data?	16
From leaves to roots: Biophysical models of transport of substances in plants	15
The HCN channel as a pharmacological target: Why, where, and how to block it	15
Computational approaches for modeling and structural design of biological systems: A comprehensive review	14
A survey on gene expression data analysis using deep learning methods for cancer diagnosis	14
Action potential alterations induced by single F11 neuronal cell loading	14
Life is a mobius strip	14
The funny current: Even funnier than 40 years ago. Uncanonical expression and roles of HCN/f channels all over the body	14
Reverting to single-cell biology: The predictions of the atavism theory of cancer	14
Making use of noise in biological systems	14
Do plants pay attention? A possible phenomenological-empirical approach	13
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation	13
A revised central dogma for the 21st century: All biology is cognitive information processing	13
Structural interpretation of cryo-EM image reconstructions	13
Re-visiting the Frank-Starling nexus	13
What can evolutionary biology learn from cancer biology?	13
Computational techniques for the automated detection of mycobacterium tuberculosis from digitized sputum smear microscopic images: A systematic review	13
The somatic molecular evolution of cancer: Mutation, selection, and epistasis	12
Atomic force microscopy (AFM) and its applications to bone-related research	12
The biological effects of radiation-induced liver damage and its natural protective medicine	12
The significance of bioelectricity on all levels of organization of an organism. Part 1: From the subcellular level to cells	12
Biology transcends the limits of computation	12
Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM	12
The role of viscoelasticity in long time cell rearrangement	12
Cellular and organismal agency – Not based on genes: A comment on Baverstock	12
An overview of the biological effects of extremely low frequency electromagnetic fields combined with ionizing radiation	12

Insulin fibrillation: Strategies for inhibition	12
The living state: How cellular excitability is controlled by the thermodynamic state of the membrane	12
Do the functional properties of HCN1 mutants correlate with the clinical features in epileptic patients?	12
State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps	12
HCN4 current during human sinoatrial node-like action potentials	11
The thermodynamic soliton theory of the nervous impulse and possible medical implications	11
Evidence of the static magnetic field effects on bone-related diseases and bone cells	11
Exosomes in bone remodeling and breast cancer bone metastasis	11
Biological effects of rotating magnetic field: A review from 1969 to 2021	11
Autonomic modulation of sinoatrial node: Role of pacemaker current and calcium sensitive adenylyl cyclase isoforms	11
Efficient metadata mining of web-accessible neural morphologies	11
High resolution single particle Cryo-EM refinement using JSPR	11
Roles of ATM and ATR in DNA double strand breaks and replication stress	11
Integration of mechanics and biology in computer simulation of bone remodeling	11
The important consequences of the reversible heat production in nerves and the adiabaticity of the action potential	11
Optical clearing in cardiac imaging: A comparative study	11
Glycometabolism reprogramming: Implications for cardiovascular diseases	11