Progress in Biophysics & Molecular Biology

Article	Citations
Ferroptosis as an emerging target in inflammatory diseases	108
Recent treatment progress of triple negative breast cancer	78
Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies	67
In-silico human electro-mechanical ventricular modelling and simulation for drug-induced pro-arrhythmia and inotropic risk assessment	53
Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease	43
Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes	40
Cytochrome bd in Mycobacterium tuberculosis: A respiratory chain protein involved in the defense against antibacterials	38
Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors	36
Bioelectrical approaches to cancer as a problem of the scaling of the cellular self	34
ROS-induced cell cycle arrest as a mechanism of resistance in polyaneuploid cancer cells (PACCs)	34
Supervised and unsupervised algorithms for bioinformatics and data science	33
Human coronavirus spike protein-host receptor recognition	31
Compressed sensing in fluorescence microscopy	30
Localized reconstruction in Scipion expedites the analysis of symmetry mismatches in cryo-EM data	30
Targeting the cytochrome oxidases for drug development in mycobacteria	29
Forecasting the timeframe of 2019-nCoV and human cells interaction with reverse engineering	29
A free energy principle for generic quantum systems	27
Towards high-throughput in situ structural biology using electron cryotomography	27
Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation	27
Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system	26
Intrinsic disorder in proteins: Relevance to protein assemblies, drug design and host-pathogen interactions	26
The multiple biological roles of the cholinesterases	26
Removing striping artifacts in light-sheet fluorescence microscopy: a review	26
Mesoscale microscopy and image analysis tools for understanding the brain	25
Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness	25

Beyond the modern synthesis: A framework for a more inclusive biological synthesis	25
Curcumin and cancer; are long non-coding RNAs missing link?	24
Two-phased evolution: Genome chaos-mediated information creation and maintenance	23
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents	23
The murburn precepts for aerobic respiration and redox homeostasis	23
Unique structural and mechanistic properties of mycobacterial F-ATP synthases: Implications for drug design	22
Ih from synapses to networks: HCN channel functions and modulation in neurons	22
A specific role of magnetic isotopes in biological and ecological systems. Physics and biophysics beyond	22
What prevents mainstream evolutionists teaching the whole truth about how genomes evolve?	21
Cardiac pacing using transmural multi-LED probes in channelrhodopsin-expressing mouse hearts	21
Towards a clearer view of sympathetic innervation of cardiac and skeletal muscles	19
The role of stochasticity in biological communication processes	18
The resolution revolution in X-ray diffraction, Cryo-EM and other Technologies	18
Living systems approached from physical principles	18
Cellular senomic measurements in Cognition-Based Evolution	17
Beyond pacemaking: HCN channels in sinoatrial node function	17
Quantum information theoretic approach to the mind–brain problem	17
Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response	17
The gene: An appraisal	17
Computational models of cardiac hypertrophy	17
Transfer RNA: The molecular demiurge in the origin of biological systems	17
Fanconi anemia-independent DNA inter-strand crosslink repair in eukaryotes	16
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease	15
A systematic review on machine learning and deep learning techniques in cancer survival prediction	15
New role of TRPM4 channel in the cardiac excitation-contraction coupling in response to physiological and pathological hypertrophy in mouse	15
Introduction: Novel insights into TB research and drug discovery	14
Cellular Darwinism: Regulatory networks, stochasticity, and selection in cancer development	14
An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines	14
Recent progress in optical voltage-sensor technology and applications to cardiac research: from single cells to whole hearts	14
Mathematical modelling of the mechano-electric coupling in the human cardiomyocyte electrically connected with fibroblasts	14
Roles of ATM and ATR in DNA double strand breaks and replication stress	14
Non-canonical roles of connexins	14
Biophysical analysis of an HCN1 epilepsy variant suggests a critical role for S5 helix Met-305 in voltage sensor to pore domain coupling	14
Treasuring the computational approach in medicinal plant research	14
Targeted protein degradation in antibacterial drug discovery?	14
Life is a mobius strip	13
In vitro cell stretching technology (IsoStretcher) as an approach to unravel Piezo1-mediated cardiac mechanotransduction	13
Unique structural features of the Mycobacterium ribosome	13
Tools for visualizing and analyzing Fourier space sampling in Cryo-EM	13
The living state: How cellular excitability is controlled by the thermodynamic state of the membrane	13
Reverting to single-cell biology: The predictions of the atavism theory of cancer	12
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation	12
What can evolutionary biology learn from cancer biology?	12
Ca2+ currents in cardiomyocytes: How to improve interpretation of patch clamp data?	12
Action potential alterations induced by single F11 neuronal cell loading	12
DNA replication stress and emerging prospects for PARG inhibitors in ovarian cancer therapy	12
Inosine and its methyl derivatives: Occurrence, biogenesis, and function in RNA	11
Different methods, techniques and their limitations in protein structure prediction: A review	11
The HCN channel as a pharmacological target: Why, where, and how to block it	11
Editorial: Charles Darwin, Jean-Baptiste Lamarck, and 21st century arguments on the fundamentals of biology	11

Biology transcends the limits of computation	11
Further insights into the molecular complexity of the human sinus node – The role of ‘novel’ transcription factors and microRNAs	11
The important consequences of the reversible heat production in nerves and the adiabaticity of the action potential	11
T cell receptors, mechanosensors, catch bonds and immunotherapy	11
HCN4 current during human sinoatrial node-like action potentials	11
No light without the dark: Perspectives and hindrances for translation of cardiac optogenetics	11
State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps	11
The ATPases of the mycobacterial type VII secretion system: Structural and mechanistic insights into secretion	11
The funny current: Even funnier than 40 years ago. Uncanonical expression and roles of HCN/f channels all over the body	11
Structural interpretation of cryo-EM image reconstructions	10
Clustering polymorphs of tau and IAPP fibrils with the CHEP algorithm	10
From leaves to roots: Biophysical models of transport of substances in plants	10
The biological effects of radiation-induced liver damage and its natural protective medicine	10
Computational techniques for the automated detection of mycobacterium tuberculosis from digitized sputum smear microscopic images: A systematic review	10
Efficient metadata mining of web-accessible neural morphologies	10
Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM	10
Biophysical mechanisms underlying the effects of static magnetic fields on biological systems	10
Optical clearing in cardiac imaging: A comparative study	10
The role of mechanosensitive Piezo1 channel in diseases	10
Do the functional properties of HCN1 mutants correlate with the clinical features in epileptic patients?	10
Neo-Darwinism must Mutate to survive	9
High resolution single particle Cryo-EM refinement using JSPR	9
The somatic molecular evolution of cancer: Mutation, selection, and epistasis	9
Do plants pay attention? A possible phenomenological-empirical approach	9
DNA glycosylase NEIL2 functions in multiple cellular processes	9
Re-visiting the Frank-Starling nexus	9
Xanthohumol: An underestimated, while potent and promising chemotherapeutic agent in cancer treatment	9
The surprising heart revisited: an early history of the funny current with modern lessons	9
Diverse roles of mtDNA in schizophrenia: Implications in its pathophysiology and as biomarker for cognitive impairment	9
Tuberculosis control in crisis-causes and solutions	9
Targeting cell-matrix interface mechanobiology by integrating AFM with fluorescence microscopy	8
The thermodynamic soliton theory of the nervous impulse and possible medical implications	8
Sound pulses in lipid membranes and their potential function in biology	8
The cancer puzzle: Welcome to organicism	8
Exosomes in bone remodeling and breast cancer bone metastasis	8
Roles of ATM and ATR in DNA double strand breaks and replication stress	8
Advances in the understanding of protein misfolding and aggregation through molecular dynamics simulation	8
Autonomic modulation of sinoatrial node: Role of pacemaker current and calcium sensitive adenylyl cyclase isoforms	8
Consciousness, embodied Quantum Entanglement	8
The role of non-coding genome in the behavior of infiltrated myeloid-derived suppressor cells in tumor microenvironment; a perspective and state-of-the-art in cancer targeted therapy	8
Atomic force microscopy (AFM) and its applications to bone-related research	8
Projective mechanisms subtending real world phenomena wipe away cause effect relationships	8
Ionic channels in nerve membranes, 50 years on	8
Integration of mechanics and biology in computer simulation of bone remodeling	8
Structural basis of the (in)activity of the apical DNA damage response kinases ATM, ATR and DNA-PKcs	8
The role of viscoelasticity in long time cell rearrangement	8
TRPV2 channel-based therapies in the cardiovascular field. Molecular underpinnings of clinically relevant therapies	7
Coronavirus disease 2019 (COVID-19): Biophysical and biochemical aspects of SARS-CoV-2 and general characteristics	7
Two-photon excitation of FluoVolt allows improved interrogation of transmural electrophysiological function in the intact mouse heart	7
Evidence for DNA resonance signaling via longitudinal hydrogen bonds	7
The role of DNA demethylation in induction of stem cells	7
The impact of low intensity ultrasound on cells: Underlying mechanisms and current status	7
Cellular and organismal agency – Not based on genes: A comment on Baverstock	7
Cellular metabolism and colloids: Realistically linking physiology and biological physical chemistry	7
A revised central dogma for the 21st century: All biology is cognitive information processing	7
The epigenetic basis of evolution	7
Stages, scaffolds and strings in the spatial organisation of non-homologous end joining: Insights from X-ray diffraction and Cryo-EM	7
The funny current in genetically modified mice	7
Optical studies of membrane state during action potential propagation	7
Cellular evolution of language	6
Proteostasis impairment and ALS	6
Making use of noise in biological systems	6
Non-coding RNAs regulate autophagy process via influencing the expression of associated protein	6
Exploring the human cerebral cortex using confocal microscopy	6
Cyclic nucleotide signaling and pacemaker activity	6
Studying β and β adrenergic receptor signals in cardiac cells using FRET-based sensors	6
It's clearly the heart! Optical transparency, cardiac tissue imaging, and computer modelling	6
Distribution of data in cellular electrophysiology: Is it always normal?	6
Intercellular communication through extracellular vesicles in cancer and evolutionary biology	6
A survey on gene expression data analysis using deep learning methods for cancer diagnosis	6
HCN1 channels: A versatile tool for signal processing by primary sensory neurons	6
Current density as routine parameter for description of ionic membrane current: is it always the best option?	6
The Importance of Henry H. Heng's Genome Architecture Theory	5
A survey of pathways for mechano-electric coupling in the atria	5
Arrhythmia susceptibility in a rat model of acute atrial dilation	5
Cancer as a form of life: Musings of the cancer and evolution symposium	5
An overview of the intracellular localization of high-Z nanoradiosensitizers	5
A review of regulated self-organizing approaches for tissue regeneration	5
Expansion light sheet fluorescence microscopy of extended biological samples: Applications and perspectives	5
The evolution of evolutionary processes in organismal and cancer evolution	5

Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca2+ entry after pressure-overload induced cardiac remodelling	5
Evidence of the static magnetic field effects on bone-related diseases and bone cells	5
Innovations in ex vivo Light Sheet Fluorescence Microscopy	5
Glycometabolism reprogramming: Implications for cardiovascular diseases	5
Temporal irregularity quantification and mapping of optical action potentials using wave morphology similarity	5
Biological effects of rotating magnetic field: A review from 1969 to 2021	5
Time delay during the proton tunneling in the base pairs of the DNA double helix	5
Abiotic stress elements in in vitro potato (Solanum tuberosum L.) exposed to air-based and liquid-based ultrasound: A comparative transcriptomic assessment	5
Identification and diagnosis of long COVID-19: A scoping review	5
Cryo-EM reveals infection steps of single-stranded RNA bacteriophages	5
Insulin fibrillation: Strategies for inhibition	5
Decrypting the mechanistic basis of CRISPR/Cas9 protein	5
Genes and knowledge: Response to Baverstock, K. the gene an appraisal. https://doi.org/10.1016/j.pbiomolbio.2021.04.005	5
The problem of accuracy in single-channel open probability measurements	5
MicroRNAs: New contributors to mechano-electric coupling and atrial fibrillation	5
Machine learning approaches in diagnosing tuberculosis through biomarkers - A systematic review	5
Possible traces of resonance signaling in the genome	4
A systematic review of artificial intelligence-based COVID-19 modeling on multimodal genetic information	4
An overview of the biological effects of extremely low frequency electromagnetic fields combined with ionizing radiation	4
FTIR based approach to study EnaC mechanosensory functions	4
The genetic control paradigm in biology: What we say, and what we are entitled to mean	4
TUDCA receptors and their role on pancreatic beta cells	4
In-situ optical assessment of rat epicardial kinematic parameters reveals frequency-dependent mechanic heterogeneity related to gender	4
A special role for the genotype? Some comments on Keith Baverstock: “The gene: An appraisal”	4
The value of treating cancer as an evolutionary disease	4
The significance of bioelectricity on all levels of organization of an organism. Part 1: From the subcellular level to cells	4
Pacemaker activity and ion channels in the sinoatrial node cells: MicroRNAs and arrhythmia	4
From traditional medicine to modern oncology: Scutellarin, a promising natural compound in cancer treatment	4
Colon cancer transcriptome	4
Implication of frequency-dependent protocols in antiarrhythmic and proarrhythmic drug testing	4
The dynamic nature of the Mre11-Rad50 DNA break repair complex	4
Infrared neural stimulation at different wavelengths and pulse shapes	4
FOXI1 inhibits gastric cancer cell proliferation by activating miR-590/ATF3 axis via integrating ChIP-seq and RNA-seq data	4
The effect of magnetic fields on tumor occurrence and progression: Recent advances	4
Biological autoluminescence as a perturbance-free method for monitoring oxidation in biosystems	4
Further illusions: On key evolutionary mechanisms that could never fit with Modern Synthesis	4