OOIR: Observatory of International Research

Papers

(The TQCC of Memorias do Instituto Oswaldo Cruz is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
PPE59 antibodies in tuberculous patients and potential use for diagnosis when assayed with other rapid biomarkers	60
Genome characterisation of the first isolate of human enterovirus c99 from an acute flaccid paralysis case in Brazil	43
Impact of dengue virus infection on the cytoadherence of Plasmodium vivax-infected erythrocytes	38
Antileishmanial metallodrugs and the elucidation of new drug targets linked to post-translational modifications machinery: pitfalls and progress	32
First concrete documentation for presence of Aedes (Stegomyia) albopictus in Bolivia: dispelling previous anecdotes	32
Sublingual microcirculatory alterations in Chagas disease: an observational study in an endemic rural population	24
Insecticide resistance levels and associated mechanisms in three Aedes aegypti populations from Venezuela	23
Pharmacokinetics of two pharmaceutical presentations of benznidazole in adult Trypanosoma cruzi infected population	19
Genomic surveillance: a potential shortcut for effective Chagas disease management	19
A multicentre comparative study of serological methods for diagnosing Chagas disease in Brazil	19
Revisiting Chagas' disease diagnostic strategies in light of different scenarios of Trypanosoma cruzi infection	18
Memórias do Instituto Oswaldo Cruz celebrates 115 years of scientific publishing: what it needs to keep moving on…	18
Challenges in developing new tuberculosis vaccines	18
Antileishmanial metallodrugs and the elucidation of new drug targets linked to post-translational modifications machinery: pitfalls and progress	18
Improving in vitro screening compounds anti-Trypanosoma cruzi by GFP-expressing parasites	17
Plants of the family Lamiaceae as a source of therapeutic agents against Acanthamoeba infections	16
How people affected by Chagas disease have struggled with their negligence: history, associative movement and World Chagas Disease Day	13
Why do we still have not a vaccine against Chagas disease?	12
Concomitant use of anti-leishmanial therapy and antibacterial prophylaxis reduces plasma LPS levels and improves several aspects of experimental Leishmania infantum infection in golden hamsters	12
The multidimensional comprehension of Chagas disease. Contributions, approaches, challenges and opportunities from and beyond the Information, Education and Communication field	12
Significance of a neglected tropical disease: lessons from a paradigmatic case of ‘success in translation’	11
In vitro activity of Schinus terebinthifolius extract and fractions against Sporothrix brasiliensis	11
Intravenous whole blood transfusion results in faster recovery of vascular integrity and increased survival in experimental cerebral malaria	11
Trypanosoma cruzi and Chagas disease: diversity, progress and challenges	11
Surveillance of land molluscs infected by Angiostrongylus cantonensis (Nematoda) reveals risk areas for zoonotic eosinophilic meningitis in the State of Rio de Janeiro, Brazil	10

Transforming growth factor-ß as a therapeutic target for the cardiac damage of Chagas disease	10
Characterisation of Neisseria meningitidis cc11/ET-15 variant by whole genome sequencing	10
Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes	9
Perillyl alcohol modulates activation, permeability and integrity of human brain endothelial cells induced by Plasmodium falciparum	9
Diphtheria antitoxin treatment: from pioneer to neglected	9
A review of serological tests available in Brazil for intestinal schistosomiasis diagnosis	8
Congenital Zika virus infection in laboratory animals: a comparative review highlights translational studies on the maternal-foetal interface	8
Cross-sectional entomological monitoring combined with professional qualifications in transition areas for yellow fever and autochthonous malaria in the Atlantic Forest in Rio de Janeiro, Brazil	8
Leishmania (Leishmania) infantum DNA detection in Nyssomyia neivai in Vale do Ribeira, Paraná, Brazil	8
Iron and vitamin D intake on a diet are able to modify the in vitro immune response to Mycobacterium leprae	8
Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects	8
125 years of the plague in Brazil: lessons learnt, historical insights and contemporary challenges	7
Natural compounds based chemotherapeutic against Chagas disease and leishmaniasis: mitochondrion as a strategic target	7
Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy	7
Host cholesterol influences the activity of sterol biosynthesis inhibitors in Leishmania amazonensis	7
Evaluation of the influence of genetic variants in Cereblon gene on the response to the treatment of erythema nodosum leprosum with thalidomide	7
First report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil	6
Peeking into the mysterious world of Trypanosoma cruzi and Chagas disease	6
Heavy metal resistance in the Yanomami and Tunapuco microbiome	6
Chagas disease in the context of the 2030 agenda: global warming and vectors	6
Translational research in Chagas disease: perspectives in nutritional therapy emerging from selenium supplementation studies as a complementary treatment	5
First isolation of Mycobacterium brisbanense from humans in the Americas	5
Unique synapomorphies and high diversity in South American Raji-related Epstein-Barr virus genomes	5
Concomitant occurrence of chronic Schistosoma mansoni infection and chronic colitis restore immune imbalance and dysbiosis leading to protection against intestinal colitis and schistosome egg-induced	5
Binding of the extracellular matrix laminin-1 to Clostridioides difficile strains	5
Exploring BCG to deliver avidin fusion antigens from Schistosoma mansoni	5
Investigating the distribution of a rare Colombo-Venezuelan kissing bug, Rhodnius neivai, Lent, 1953, using geographical information system-based analyses	4
Chikungunya virus infection in the southernmost state of Brazil was characterised by self-limited transmission (2017-2019) and a larger 2021 outbreak	4
Pathophysiology and new targets for therapeutic options in Chagas heart disease	4
Cerebrospinal fluid: a target of some fungi and an overview	4
Clinical and epidemiological aspects of Delta and Gamma SARS-CoV-2 variant of concern from the western Brazilian Amazon	4
Aedes aegypti reproductive aspects: constant light significantly affects the embryonic development	4
Increased angiogenesis parallels cardiac tissue remodelling in experimental acute Trypanosoma cruzi infection	4
Reflections on Chagas disease in the Amazon	4
Waiting for a success story in prevention, control and treatment of Chagas disease in non-endemic countries	4
Challenges and perspectives in research and teaching of host pathogen interaction topics: new post-pandemic times to Brazil and other South American countries	4
The impact of probiotic administration in vivo on peritoneal mouse macrophages infected by Leishmania amazonensis ex vivo	4
The risk of vector transmission of Trypanosoma cruzi remains high in the State of Paraná	4
New possibilities for chromoblastomycosis and phaeohyphomycosis treatment: identification of two compounds from the MMV Pathogen Box® that present synergism with itraconazole	4
Different profiles of chemokines, cytokines and cell growth factors in plasma samples from patients with leprosy, leprosy reactions and households contacts	4
Genetic diversity of Trypanosoma cruzi strains isolated from chronic chagasic patients and non-human hosts in the state of São Paulo, Brazil	3
Accuracy of rapid point-of-care serological tests for leprosy diagnosis: a systematic review and meta-analysis	3
Critical analysis of Chagas disease treatment in different countries	3
A short history of innate immunity	3
Chagas disease treatment: a 120-year-old challenge to public health	3
Prognosis of chronic Chagas heart disease and other pending clinical challenges	3
Impact of gut-peripheral nervous system axis on the development of diabetic neuropathy	3
Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells	3
Microbiome and virome on indoor surfaces of an Antarctic research ship	3
Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report	3

The translational challenge in Chagas disease drug development	3
Traditional use of benznidazole with weekly clinical follow-up indicate to be an important approach for the etiologic treatment of Chagas disease	3
Lack of serological and molecular evidences of Zika virus circulation in non-human primates in three states from Brazil	3
Electrochemical immunosensor for detection of Plasmodium vivax lactate dehydrogenase	3
Population size regulation is density-dependent in Rhodnius prolixus (Hemiptera: Reduviidae) through an irritability mechanism	3
A newly bat-borne hantavirus detected in Seba’s short-tailed bats (Carollia perspicillata) in the Brazilian Atlantic Rainforest	3
COVID-19 outbreaks among crew members in non-cruise vessels anchoring in Salvador, Brazil, 2021	3
Chagas disease (American trypanosomiasis) in the context of the 2030 agenda. Insights into global warming and vector control	3
Analysis of a novel class A β-lactamase OKP-B-6 of Klebsiella quasipneumoniae: structural characterisation and interaction with commercially available drugs	3
Beyond the first case of Chagas disease: the Berenice strain as a model for understanding long-term Trypanosoma cruzi infection	3