OOIR: Observatory of International Research

Papers

(The median citation count of Memorias do Instituto Oswaldo Cruz is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease	30
Do the new triatomine species pose new challenges or strategies for monitoring Chagas disease? An overview from 1979-2021	27
The translational challenge in Chagas disease drug development	23
Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy	22
Morphology and morphogenesis of SARS-CoV-2 in Vero-E6 cells	22
Chagas disease control-surveillance in the Americas: the multinational initiatives and the practical impossibility of interrupting vector-borne Trypanosoma cruzi transmission	20
Parasitological, serological and molecular diagnosis of acute and chronic Chagas disease: from field to laboratory	17
The multidimensional comprehension of Chagas disease. Contributions, approaches, challenges and opportunities from and beyond the Information, Education and Communication field	14
Emerging and reemerging forms of Trypanosoma cruzi transmission	14
Family Herpesviridae and neuroinfections: current status and research in progress	14
Medicines for Malaria Venture COVID Box: a source for repurposing drugs with antifungal activity against human pathogenic fungi	12
Prognosis of chronic Chagas heart disease and other pending clinical challenges	12
Systematic review on the biology, ecology, genetic diversity and parasite transmission potential of Panstrongylus geniculatus (Latreille 1811) in Latin America	12
Why do we still have not a vaccine against Chagas disease?	12
Perspectives for a new drug candidate for Chagas disease therapy	11
Chagas disease in the context of the 2030 agenda: global warming and vectors	11
Urban infestation by Triatoma infestans (Hemiptera: Reduviidae), an overlooked phenomena for Chagas disease in Argentina	11
Genomics and functional genomics in Leishmania and Trypanosoma cruzi: statuses, challenges and perspectives	10
Accuracy of rapid point-of-care serological tests for leprosy diagnosis: a systematic review and meta-analysis	10
Fast surveillance response reveals the introduction of a new yellow fever virus sub-lineage in 2021, in Minas Gerais, Brazil	10
Computational approaches towards the discovery and optimisation of cruzain inhibitors	9
Evaluation of LAMP for the diagnosis of Loa loa infection in dried blood spots compared to PCR-based assays and microscopy	9
Natural compounds based chemotherapeutic against Chagas disease and leishmaniasis: mitochondrion as a strategic target	9
Comparison of viral load between saliva and nasopharyngeal swabs for SARS-CoV2: the role of days of symptoms onset on diagnosis	9
A short history of innate immunity	9

Population movements, borders, and Chagas disease	9
Validation of ELISA with recombinant antigens in serological diagnosis of canine Leishmania infantum infection	8
Transmission-blocking compound candidates against Plasmodium vivax using P. berghei as an initial screening	7
Is the mitochondrion a promising drug target in trypanosomatids?	7
Multi-therapeutic strategy targeting parasite and inflammation-related alterations to improve prognosis of chronic Chagas cardiomyopathy: a hypothesis-based approach*	7
Mycolicibacterium fortuitum genomic epidemiology, resistome and virulome	7
Mechanism of action of glycyrrhizin against Plasmodium falciparum	6
An emerging paradigm for the origin and evolution of shelled amoebae, integrating advances from molecular phylogenetics, morphology and paleontology	6
Gene expression of Paracoccidioides virulence factors after interaction with macrophages and fibroblasts	6
A history of over 40 years of potentially pathogenic free-living amoeba studies in Brazil - a systematic review	6
Molecular detection of omicron SARS-CoV-2 variant is achieved by RT-LAMP despite genomic mutations	6
Transforming growth factor-ß as a therapeutic target for the cardiac damage of Chagas disease	6
Flight tone characterisation of the South American malaria vector Anopheles darlingi (Diptera: Culicidae)	6
Transmission cluster of COVID-19 cases from Uruguay: emergence and spreading of a novel SARS-CoV-2 ORF6 deletion	5
Detection of non-tuberculosus mycobacteria (NTMs) in lung samples using 16S rRNA	5
Evaluation of cytochrome b sequence to identify Leishmania species and variants: the case of Panama	5
Chagas disease affects the human placental barrier’s turnover dynamics during pregnancy	5
Sand fly behavior: much more than weak-flying	5
Differential expression profiles of miRNAs and their putative targets in Schistosoma mansoni during its life cycle	5
Critical analysis of Chagas disease treatment in different countries	5
Multidisciplinary approach detects speciation within the kissing bug Panstrongylus rufotuberculatus populations (Hemiptera, Heteroptera, Reduviidae)	5
Article-processing charges as a barrier for science in low-to-medium income regions	5
First report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil	5
Epidemiology of paracoccidioidomycosis in Venezuela: a retrospective study from 1954 to 2019	5
Antigenicity and adhesiveness of a Plasmodium vivax VIR-E protein from Brazilian isolates	5
How people affected by Chagas disease have struggled with their negligence: history, associative movement and World Chagas Disease Day	5
First report of putative Leishmania RNA virus 2 (LRV2) in Leishmania infantum strains from canine and human visceral leishmaniasis cases in the southeast of Brazil	5
Giardiasis in urban and rural Amazonas, Brazil is driven by zoonotic and cosmopolitan A and B assemblages	4
Molecular aspects of Chikungunya virus infections in cancer patients	4
Should COVID-19 be branded to viral thrombotic fever?	4
Anxiety, depression, and memory loss in Chagas disease: a puzzle far beyond neuroinflammation to be unpicked and solved*	4
Cerebrospinal fluid: a target of some fungi and an overview	4
Clinical and epidemiological aspects of Delta and Gamma SARS-CoV-2 variant of concern from the western Brazilian Amazon	4
Enterovirus infection and its relationship with neurodegenerative diseases	4
Molecular epidemiology of Mycobacterium tuberculosis in Brazil before the whole genome sequencing era: a literature review	4
SARS-CoV-2 variant N.9 identified in Rio de Janeiro, Brazil	4
Inhibition of nitric oxide production of activated mice peritoneal macrophages is independent of the Toxoplasma gondii strain	4
The adaptation of SARS-CoV-2 to humans	4
Chagas disease treatment: a 120-year-old challenge to public health	4
Toxoplasma gondii in the faeces of wild felids from the Atlantic Forest, Brazil	4
Geographical origin of chronic Chagas disease patients in Brazil impacts the performance of commercial tests for anti-T. cruzi IgG	3
COVID-19 diagnosis by RT-qPCR in alternative specimens	3
First report and genome sequencing of SARS-CoV-2 in a cat (Felis catus) in Colombia	3
Prevalence and force of Plasmodium vivax blood-stage infection and associated clinical malaria burden in the Brazilian Amazon	3
Electrochemical immunosensor for detection of Plasmodium vivax lactate dehydrogenase	3
Translational research in Chagas disease: perspectives in nutritional therapy emerging from selenium supplementation studies as a complementary treatment	3
Suitability of methods for Plasmodium falciparum cultivation in atmospheric air	3
A new Trypanosoma cruzi genotyping method enables high resolution evolutionary analyses	3
Significance of a neglected tropical disease: lessons from a paradigmatic case of ‘success in translation’	3
First report of Leishmania (Mundinia) martiniquensis in South American territory and confirmation of Leishbunyavirus infecting this parasite in a mare	3

Design of a specific peptide against phenolic glycolipid-1 from Mycobacterium leprae and its implications in leprosy bacilli entry	3
Mitochondrial dysfunction on Leishmania (Leishmania) amazonensis induced by ketoconazole: insights into drug mode of action	3
Transcriptome comparison of dengue-susceptible and -resistant field derived strains of Colombian Aedes aegypti using RNA-sequencing	3
Host cholesterol influences the activity of sterol biosynthesis inhibitors in Leishmania amazonensis	3
Callitrichine gammaherpesvirus 3 and Human alphaherpesvirus 1 in New World Primate negative for yellow fever virus in Rio de Janeiro, Brazil	3
New possibilities for chromoblastomycosis and phaeohyphomycosis treatment: identification of two compounds from the MMV Pathogen Box® that present synergism with itraconazole	3
Reemergence of human malaria in Atlantic Forest of Rio Grande do Sul, Brazil	3
Lipid droplets of protozoan parasites: survival and pathogenicity	3
Clinically silent Plasmodium vivax infections in native Amazonians of northwestern Brazil: acquired immunity or low parasite virulence?	2
Revisiting Chagas' disease diagnostic strategies in light of different scenarios of Trypanosoma cruzi infection	2
The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil	2
Identification and characterisation of SARS-CoV-2 and Human alphaherpesvirus 1 from a productive coinfection in a fatal COVID-19 case	2
Impact of gut-peripheral nervous system axis on the development of diabetic neuropathy	2
Revisiting trypanosomatid nucleoside diphosphate kinases	2
Benznidazole treatment decreases IL-6 levels in Trypanosoma cruzi-infected human adipocytes differentiated from adipose tissue-derived stem cells	2
A review of serological tests available in Brazil for intestinal schistosomiasis diagnosis	2
The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil	2
Increased angiogenesis parallels cardiac tissue remodelling in experimental acute Trypanosoma cruzi infection	2
Expansion of T regulatory lymphocytes by murine bone marrow dendritic cells previously stimulated with Anisakis simplex larval antigens	2
Genetic diversity of Trypanosoma cruzi strains isolated from chronic chagasic patients and non-human hosts in the state of São Paulo, Brazil	2
Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon	2
Past and future of trypanosomatids high-throughput phenotypic screening	2
Different profiles and epidemiological scenarios: past, present and future	2
How is global change affecting Chagas disease landscapes?	2
The history of Chagas disease: reflections on science in action	2
The scientific publication of the Memórias do Instituto Oswaldo Cruz (1909-2020): a history of contribution to the biomedical sciences	2
Characterising four Sarconesiopsis magellanica (Diptera: Calliphoridae) larval fat body-derived antimicrobial peptides	2
Giardia lamblia-infected preschoolers present growth delays independent of the assemblage A, B or E	2
Insecticide resistance levels and associated mechanisms in three Aedes aegypti populations from Venezuela	2
Presence of trypanosomatids, with emphasis on Leishmania, in Rodentia and Didelphimorphia mammals of a rural settlement in the central Amazon region	2
HIV/Aids and COVID-19 in Brazil: in four decades, two antithetical approaches to face serious pandemics	2
Stronger control-surveillance systems for vector-borne Chagas disease	2
In vitro activity of Schinus terebinthifolius extract and fractions against Sporothrix brasiliensis	2
Open-source real-time quantitative RT-PCR-based on a RNA standard for the assessment of SARS-CoV-2 viral load	1
Leptospira interrogans insoluble fraction as a potential antigen source for lateral flow immunochromatography	1
Relevance of national, regional and global virome projects on pandemics prediction, prevention, and control: a social network analysis of GVP-citing articles	1
Heterogeneous persistence of Mycobacterium leprae in oral and nasal mucosa of multibacillary patients during multidrug therapy	1
The challenge of risk assessment in the riddle of Chagas heart disease	1
Histone deacetylase (HDAC) inhibitors- based drugs are effective to control Mycobacterium tuberculosis infection and promote the sensibility for rifampicin in MDR strain	1
Evaluation of the influence of genetic variants in Cereblon gene on the response to the treatment of erythema nodosum leprosum with thalidomide	1
Vitellogenin genes are transcribed in Culex quinquefasciatus ovary	1
Molecular diversity of genes related to biological rhythms (period and timeless) and insecticide resistance (Na V and ace-1) in Anopheles darlingi	1
Lack of serological and molecular evidences of Zika virus circulation in non-human primates in three states from Brazil	1
Perillyl alcohol modulates activation, permeability and integrity of human brain endothelial cells induced by Plasmodium falciparum	1
Binding of the extracellular matrix laminin-1 to Clostridioides difficile strains	1
Intravenous whole blood transfusion results in faster recovery of vascular integrity and increased survival in experimental cerebral malaria	1
Comment on “The translational challenge in Chagas disease drug development” by Kratz et al.	1
Pathophysiology and new targets for therapeutic options in Chagas heart disease	1
Air in the tires: towards an achievable, efficacious and timely diagnosis for Chagas disease	1
Homozygotes NAT2*5B slow acetylators are highly associated with hepatotoxicity induced by anti-tuberculosis drugs	1
Antileishmanial metallodrugs and the elucidation of new drug targets linked to post-translational modifications machinery: pitfalls and progress	1
In vitro immunogenic profile of recombinant SARS-CoV2 S1-RBD peptide in murine macrophage and microglial cells	1
Molecular mechanisms of action of trypanocidal and leishmanicidal drugs with focus on novel chemotherapeutic strategies: creation of a Brazilian multicentre working group	1
Immunoanalysis of different antigenic preparations of Angiostrongylus cantonensis for neuroangiostrongyliasis diagnosis improvement	1
Leishmania enriettii visceralises in the trachea, lungs, and spleen of Cavia porcellus	1
Zoonotic Giardia duodenalis assemblage A in northern sloth from Brazilian Amazon	1
Matrix-assisted laser desorption/ionisation-time of flight mass spectrometry azole susceptibility assessment in Candida and Aspergillus species	1
Primary infection of BALB/c mice with a dengue virus type 4 strain leads to kidney injury	1
Unique synapomorphies and high diversity in South American Raji-related Epstein-Barr virus genomes	1
Proteolytic inhibitors as alternative medicines to treat trypanosomatid-caused diseases: experience with calpain inhibitors	1
Characterisation of Neisseria meningitidis cc11/ET-15 variant by whole genome sequencing	1
In vitro susceptibility of eighteen clinical isolates of human monkeypox virus to tecovirimat	1
Animal models and SARS-CoV-2-induced pulmonary and neurological injuries	1
Unveiling the genome of a high-risk pandrug-resistant Klebsiella pneumoniae emerging in the Brazilian Amazon Region, 2022	1
Exploring the performance of Escherichia coli outer membrane vesicles as a tool for vaccine development against Chagas disease	1
Heavy metal resistance in the Yanomami and Tunapuco microbiome	1
A straightforward one-step strategy for SARS-CoV-2 diagnosis and screening of variants of concern: a multicentre study	1
Chagas disease (American trypanosomiasis) in the context of the 2030 agenda. Insights into global warming and vector control	1
Tracing the relationship among HIV-1 sub-subtype F1 strains: a phylodynamic perspective	1
Worldwide distribution, symptoms and diagnosis of the coinfections between malaria and arboviral diseases: a systematic review	1
The challenges for targeting Chagas disease for elimination as a public health problem	1
Simple and promising paper-based electrochemical platform for serological detection of American tegumentary leishmaniasis	1
Brazilian science: towards extinction?	1
Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes	1
An updated gene regulatory network reconstruction of multidrug-resistant Pseudomonas aeruginosa CCBH4851	1
Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease	1
Trypanosoma cruzi and Chagas disease: diversity, progress and challenges	1
Mapping Yellow fever epidemics as a potential indicator of the historical range of Aedes aegypti in the United States	1
Reflections on Chagas disease in the Amazon	1