OOIR: Observatory of International Research

Papers

(The TQCC of Essays in Biochemistry is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
CRISPR screening in cancer stem cells	183
How viral proteins bind short linear motifs and intrinsically disordered domains	149
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	147
Phase separation of the microtubule-associated protein tau	104
Butyrate-producing colonic clostridia: picky glycan utilization specialists	78
Inter-species horizontal transfer of biosynthetic gene clusters: an evolutionary driver for chemical diversity in bacterial communities	70
Salicylic acid and jasmonic acid crosstalk in plant immunity	68
Apoplastic and vascular defences	65
Heterologous expression of NRPS and PKS pathways in Escherichia coli : from bottlenecks to biosynthetic platforms	65
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	62
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	61
Versatile roles of inositol hexakisphosphate in the ubiquitin-proteasome system	60
The dual role of the ubiquitin–proteasome system in photomorphogenesis	56
The role of methionine synthases in fungal metabolism and virulence	54
Astrocytes in memory formation and maintenance	53
Malate dehydrogenase: a story of diverse evolutionary radiation	52
A special issue of Essays in Biochemistry on evolutionary developmental biology	50
Expanding perspectives on specialized metabolism in Streptomyces bacteria	50
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	49
Mass spectrometric insights into protein aggregation	48
Branched-chain amino acid biosynthesis in fungi	48
Colony politics to chemical warfare: phenotypic plasticity in Streptomyces	47
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	46
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	45
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	42

Functional amyloid in a lipid-like environment: a merry dance of many steps	41
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	40
Hemicellulolytic enzymes in lignocellulose processing	39
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	38
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	38
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	36
Nitrification in acidic and alkaline environments	35
Imaging of biofilms using cryo-scanning electron microscopy	35
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	32
Phase separation and other forms of α-Synuclein self-assemblies	32
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	29
Regulation of R-loops by nucleic acid and protein modifications	29
Mesolens imaging in microbiology	29
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	29
The molecular basis of cereal grain proteostasis	29
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	28
Plant proteostasis: a proven and promising target for crop improvement	27
Developing physical seed priming as a practical tool for stress-resilient crop production	27
Astrocyte heterogeneity and interactions with local neural circuits	26
NEDD8, stress granules, and amyotrophic lateral sclerosis: unveiling the therapeutic potential of the NEDP1 protease	26
Oxidative stress – Alzheimer’s disease – DNA methylation: the role of arsenic	25
Harnessing neutrophil plasticity for HCC immunotherapy	23
Evolution of resistance (R) gene specificity	23
Epigenetics and chemical exposures	23
UFM1 at the endoplasmic reticulum: linking ER stress, ribosome quality control, and ER-phagy	23
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	23
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	23
Reactive oxygen species and oxidative signalling in plants	23
Crossroads between copper ions and amyloid formation in Parkinson’s disease	22
The new age of the phage	22
Evo-devo perspectives on cancer	21
How phosphorylation impacts intrinsically disordered proteins and their function	21
Sulfate: a neglected (but potentially highly relevant) anion	21
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	20
WNT signaling and cancer stemness	20
When, where, and why specialised metabolites are produced: inferring function from expression control	20
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	20
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	20
Quantification of persulfidation on specific proteins: are we nearly there yet?	19
Using epigenetic clocks in environmental epigenetics: recommendations for estimating biological aging in perinatal and pediatric samples	19
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	19
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	19
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	18
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	18
The COP9 signalosome variants CSNCSN7A and CSNCSN7B form complexes with specific CRLs which are targets of autophagy	18
Immunologically relevant effects of radiation therapy on the tumor microenvironment	18
A guide to Direct Pathway Cloning (DiPaC) for natural product discovery	18
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	18
Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy	18