OOIR: Observatory of International Research

Papers

(The TQCC of Essays in Biochemistry is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
CRISPR screening in cancer stem cells	178
How viral proteins bind short linear motifs and intrinsically disordered domains	146
Inter-species horizontal transfer of biosynthetic gene clusters: an evolutionary driver for chemical diversity in bacterial communities	142
Salicylic acid and jasmonic acid crosstalk in plant immunity	101
Butyrate-producing colonic clostridia: picky glycan utilization specialists	71
Phase separation of the microtubule-associated protein tau	68
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	66
The role of methionine synthases in fungal metabolism and virulence	63
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	61
Astrocytes in memory formation and maintenance	61
Malate dehydrogenase: a story of diverse evolutionary radiation	60
Versatile roles of inositol hexakisphosphate in the ubiquitin-proteasome system	59
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	55
Apoplastic and vascular defences	53
The dual role of the ubiquitin–proteasome system in photomorphogenesis	51
Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	50
A special issue of Essays in Biochemistry on evolutionary developmental biology	49
Mass spectrometric insights into protein aggregation	48
Branched-chain amino acid biosynthesis in fungi	47
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	47
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	46
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	46
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	46
Functional amyloid in a lipid-like environment: a merry dance of many steps	45
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	40

Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	39
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	39
Nitrification in acidic and alkaline environments	38
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	38
Hemicellulolytic enzymes in lignocellulose processing	38
Phase separation and other forms of α-Synuclein self-assemblies	35
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	32
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	32
Regulation of R-loops by nucleic acid and protein modifications	32
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	29
The molecular basis of cereal grain proteostasis	29
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	29
Plant proteostasis: a proven and promising target for crop improvement	28
NEDD8, stress granules, and amyotrophic lateral sclerosis: unveiling the therapeutic potential of the NEDP1 protease	28
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	28
Evolution of resistance (R) gene specificity	26
UFM1 at the endoplasmic reticulum: linking ER stress, ribosome quality control, and ER-phagy	26
Harnessing neutrophil plasticity for HCC immunotherapy	25
Astrocyte heterogeneity and interactions with local neural circuits	25
Oxidative stress – Alzheimer’s disease – DNA methylation: the role of arsenic	25
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	24
Sulfate: a neglected (but potentially highly relevant) anion	23
The new age of the phage	23
Epigenetics and chemical exposures	23
WNT signaling and cancer stemness	22
Evo-devo perspectives on cancer	22
Crossroads between copper ions and amyloid formation in Parkinson’s disease	22
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	21
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	21
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	21
When, where, and why specialised metabolites are produced: inferring function from expression control	21
How phosphorylation impacts intrinsically disordered proteins and their function	21
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	21
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	20
Immunologically relevant effects of radiation therapy on the tumor microenvironment	20
Quantification of persulfidation on specific proteins: are we nearly there yet?	19
The COP9 signalosome variants CSNCSN7A and CSNCSN7B form complexes with specific CRLs which are targets of autophagy	19
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	19
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	18
Molecular plant immunity against biotrophic, hemibiotrophic, and necrotrophic fungi	18
Using epigenetic clocks in environmental epigenetics: recommendations for estimating biological aging in perinatal and pediatric samples	18
Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy	18
Ubiquitin signatures on aggregating proteins in neurodegeneration	18
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	18
Evolution and functional diversification of yeast sugar transporters	18