OOIR: Observatory of International Research

Papers

(The TQCC of Essays in Biochemistry is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
CRISPR screening in cancer stem cells	447
Ligands and DNA in the allosteric control of retinoid receptors function	126
Phase separation of the microtubule-associated protein tau	120
Butyrate-producing colonic clostridia: picky glycan utilization specialists	117
How viral proteins bind short linear motifs and intrinsically disordered domains	98
Use of electroconductive biomaterials for engineering tissues by 3D printing and 3D bioprinting	91
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	90
3D Bioprinting for fabrication of tissue models of COVID-19 infection	85
Salicylic acid and jasmonic acid crosstalk in plant immunity	72
Plant long non-coding RNAs in the regulation of transcription	65
Malate dehydrogenase: a story of diverse evolutionary radiation	57
Perspective on pros and cons of microlearning in health education	52
Mineralocorticoid receptor actions in cardiovascular development and disease	51
The role of methionine synthases in fungal metabolism and virulence	49
Astrocytes in memory formation and maintenance	47
Comparative genomics in the search for conserved long noncoding RNAs	44
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	43
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	43
Apoplastic and vascular defences	42
Mass spectrometric insights into protein aggregation	40
A special issue of Essays in Biochemistry on evolutionary developmental biology	40
Branched-chain amino acid biosynthesis in fungi	40
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	37
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	36
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	36

Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	36
SINEUPs: a novel toolbox for RNA therapeutics	34
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	33
Nitrification in acidic and alkaline environments	32
Functional amyloid in a lipid-like environment: a merry dance of many steps	32
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	32
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	32
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	30
Hemicellulolytic enzymes in lignocellulose processing	29
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	29
Phase separation and other forms of α-Synuclein self-assemblies	28
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	28
RNA-binding protein dysfunction in neurodegeneration	28
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	28
The molecular basis of cereal grain proteostasis	27
Vesicular dysfunction and pathways to neurodegeneration	27
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	25
Strategies for inclusion of growth factors into 3D printed bone grafts	25
Membrane lipid raft homeostasis is directly linked to neurodegeneration	25
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	25
Plant proteostasis: a proven and promising target for crop improvement	25
Nuclear receptor Nur77: its role in chronic inflammatory diseases	24
Estrogen receptors and the aging brain	24
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	22
Long non-coding RNAs associated with infection and vaccine-induced immunity	22
Oxidative stress – Alzheimer’s disease – DNA methylation: the role of arsenic	22
Laser-based bioprinting for multilayer cell patterning in tissue engineering and cancer research	22
Evolution of resistance (R) gene specificity	22
Long non-coding RNAs and splicing	21
Sulfate: a neglected (but potentially highly relevant) anion	21
Functional annotation of lncRNA in high-throughput screening	21
Harnessing neutrophil plasticity for HCC immunotherapy	21
Astrocyte heterogeneity and interactions with local neural circuits	21
Evo-devo perspectives on cancer	20
The non-coding genome in genetic brain disorders: new targets for therapy?	20
Crossroads between copper ions and amyloid formation in Parkinson’s disease	19
The new age of the phage	19
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	19
WNT signaling and cancer stemness	18
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	18
Quantification of persulfidation on specific proteins: are we nearly there yet?	18
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	18
How phosphorylation impacts intrinsically disordered proteins and their function	18
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	18
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	18
Immunologically relevant effects of radiation therapy on the tumor microenvironment	17
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	17
Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling	17
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	17
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases	17

Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	17
3D cell aggregate printing technology and its applications	17
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	17