OOIR: Observatory of International Research

Papers

(The TQCC of Essays in Biochemistry is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
CRISPR screening in cancer stem cells	134
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	131
Ligands and DNA in the allosteric control of retinoid receptors function	130
How viral proteins bind short linear motifs and intrinsically disordered domains	112
Butyrate-producing colonic clostridia: picky glycan utilization specialists	109
Phase separation of the microtubule-associated protein tau	106
Salicylic acid and jasmonic acid crosstalk in plant immunity	100
Astrocytes in memory formation and maintenance	76
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	69
Apoplastic and vascular defences	57
The role of methionine synthases in fungal metabolism and virulence	57
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	54
Mineralocorticoid receptor actions in cardiovascular development and disease	52
The dual role of the ubiquitin–proteasome system in photomorphogenesis	51
Perspective on pros and cons of microlearning in health education	47
Malate dehydrogenase: a story of diverse evolutionary radiation	46
Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	46
A special issue of Essays in Biochemistry on evolutionary developmental biology	44
Branched-chain amino acid biosynthesis in fungi	42
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	42
Mass spectrometric insights into protein aggregation	41
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	41
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	40
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	40
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	37

Nitrification in acidic and alkaline environments	36
Functional amyloid in a lipid-like environment: a merry dance of many steps	36
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	36
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	35
Hemicellulolytic enzymes in lignocellulose processing	35
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	35
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	34
The molecular basis of cereal grain proteostasis	33
Phase separation and other forms of α-Synuclein self-assemblies	32
RNA-binding protein dysfunction in neurodegeneration	32
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	30
Regulation of R-loops by nucleic acid and protein modifications	30
Vesicular dysfunction and pathways to neurodegeneration	29
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	28
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	28
Estrogen receptors and the aging brain	27
Plant proteostasis: a proven and promising target for crop improvement	27
Nuclear receptor Nur77: its role in chronic inflammatory diseases	26
Membrane lipid raft homeostasis is directly linked to neurodegeneration	25
Oxidative stress – Alzheimer’s disease – DNA methylation: the role of arsenic	25
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	24
Harnessing neutrophil plasticity for HCC immunotherapy	23
UFM1 at the endoplasmic reticulum: linking ER stress, ribosome quality control, and ER-phagy	23
Astrocyte heterogeneity and interactions with local neural circuits	22
Sulfate: a neglected (but potentially highly relevant) anion	22
Evolution of resistance (R) gene specificity	22
Evo-devo perspectives on cancer	21
Crossroads between copper ions and amyloid formation in Parkinson’s disease	21
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	21
The new age of the phage	21
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	20
How phosphorylation impacts intrinsically disordered proteins and their function	20
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	20
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	20
WNT signaling and cancer stemness	20
Using epigenetic clocks in environmental epigenetics: recommendations for estimating biological aging in perinatal and pediatric samples	19
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	19
Quantification of persulfidation on specific proteins: are we nearly there yet?	19
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	19
Immunologically relevant effects of radiation therapy on the tumor microenvironment	19
The COP9 signalosome variants CSNCSN7A and CSNCSN7B form complexes with specific CRLs which are targets of autophagy	19
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	19
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	18
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases	18
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	18