OOIR: Observatory of International Research

Papers

(The median citation count of Essays in Biochemistry is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
CRISPR screening in cancer stem cells	145
How viral proteins bind short linear motifs and intrinsically disordered domains	125
Butyrate-producing colonic clostridia: picky glycan utilization specialists	124
Salicylic acid and jasmonic acid crosstalk in plant immunity	84
Phase separation of the microtubule-associated protein tau	62
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	55
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	54
The role of methionine synthases in fungal metabolism and virulence	54
Perspective on pros and cons of microlearning in health education	51
Astrocytes in memory formation and maintenance	51
The dual role of the ubiquitin–proteasome system in photomorphogenesis	46
Malate dehydrogenase: a story of diverse evolutionary radiation	46
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	45
Apoplastic and vascular defences	45
Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	44
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	43
A special issue of Essays in Biochemistry on evolutionary developmental biology	43
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	43
Branched-chain amino acid biosynthesis in fungi	42
Mass spectrometric insights into protein aggregation	42
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	40
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	38
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	37
Functional amyloid in a lipid-like environment: a merry dance of many steps	37
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	36

Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	34
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	34
Hemicellulolytic enzymes in lignocellulose processing	34
Nitrification in acidic and alkaline environments	33
Phase separation and other forms of α-Synuclein self-assemblies	30
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	28
Regulation of R-loops by nucleic acid and protein modifications	27
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	27
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	26
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	26
The molecular basis of cereal grain proteostasis	26
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	23
Plant proteostasis: a proven and promising target for crop improvement	23
UFM1 at the endoplasmic reticulum: linking ER stress, ribosome quality control, and ER-phagy	23
NEDD8, stress granules, and amyotrophic lateral sclerosis: unveiling the therapeutic potential of the NEDP1 protease	23
Astrocyte heterogeneity and interactions with local neural circuits	22
Harnessing neutrophil plasticity for HCC immunotherapy	22
Evolution of resistance (R) gene specificity	21
Crossroads between copper ions and amyloid formation in Parkinson’s disease	21
Oxidative stress – Alzheimer’s disease – DNA methylation: the role of arsenic	21
Evo-devo perspectives on cancer	21
The new age of the phage	20
Epigenetics and chemical exposures	20
Sulfate: a neglected (but potentially highly relevant) anion	20
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	20
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	19
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	19
How phosphorylation impacts intrinsically disordered proteins and their function	19
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	19
WNT signaling and cancer stemness	19
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	19
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	18
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	18
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	18
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	18
Quantification of persulfidation on specific proteins: are we nearly there yet?	17
Using epigenetic clocks in environmental epigenetics: recommendations for estimating biological aging in perinatal and pediatric samples	17
The COP9 signalosome variants CSNCSN7A and CSNCSN7B form complexes with specific CRLs which are targets of autophagy	17
Immunologically relevant effects of radiation therapy on the tumor microenvironment	17
Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling	16
Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy	16
Seeing the complete picture: proteins in top-down mass spectrometry	15
Evolution and functional diversification of yeast sugar transporters	15
Chemical approaches to the sulfation of small molecules: current progress and future directions	15
Astrocytes in the pathophysiology of neuroinfection	15
Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance	15
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases	15
Mass spectrometry of intact membrane proteins: shifting towards a more native-like context	15
Indirect recognition of pathogen effectors by NLRs	15
Molecular plant immunity against biotrophic, hemibiotrophic, and necrotrophic fungi	15

Cytosolic sulfotransferases in endocrine disruption	15
A proteostasis network safeguards the chloroplast proteome	14
Mechanisms of resistance to tyrosine kinase inhibitors in liver cancer stem cells and potential therapeutic approaches	13
Kinetic modelling of glycolytic oscillations	13
Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation	13
Unconventional R proteins in the botanical tribe Triticeae	13
Understanding SUMO-mediated adaptive responses in plants to improve crop productivity	13
DNA double strand break repair: a model of specificity and complexity in SUMO signalling	13
Gut bacterial alginate degrading enzymes	13
Is the TCA cycle malate dehydrogenase-citrate synthase metabolon an illusion?	12
Developments in rapid hydrogen–deuterium exchange methods	12
Small-molecule degron mimetics for targeted protein degradation	12
Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis	12
Oxysterol sulfates in fluids, cells and tissues: how much do we know about their clinical significance, biological relevance and biophysical implications?	12
What’s new in protein kinase/phosphatase signalling in the control of plant immunity?	12
Activation and turnover of the plant immune signaling kinase BIK1: a fine balance	12
Diverse mycotoxin threats to safe food and feed cereals	12
Phage-specific antibodies: are they a hurdle for the success of phage therapy?	12
Targeting protein kinases in cancer stem cells	12
Role of p62 nuclear condensates in regulating ubiquitin-mediated proteasomal degradation	12
NUAK: never underestimate a kinase	12
Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone function	11
AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure	11
Surface-sampling mass spectrometry to study proteins and protein complexes	11
Case Study: CRISPR 101 – a novel online learning course harnessing innovative ways to teach a complex biomolecular technology	11
Ubiquitin ligases at the nexus of plant responses to biotic and abiotic stresses	11
The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer	11
Lytic polysaccharide monooxygenases: enzymes for controlled and site-specific Fenton-like chemistry	11
Different states and the associated fates of biomolecular condensates	11
Physiology of malate dehydrogenase and how dysregulation leads to disease	11
Modelling the evolution of novelty: a review	11
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses	10
Hijacking the Ubl code: bacterial manipulation of ubiquitin-like proteins	10
Sulfation pathways in times of change	10
Translational research priorities for bacteriophage therapeutics	10
Unravelling 3D growth in the moss Physcomitrium patens	10
Engagement with video content in the blended classroom	10
Mucin utilization by gut microbiota: recent advances on characterization of key enzymes	10
Structure and function of microbial α-l-fucosidases: a mini review	10
Computational methods for processing and interpreting mass spectrometry-based metabolomics	10
Immune-regulating extracellular vesicles: a new frontier in autoimmune disease therapy	10
Astrocytes as metabolic suppliers to support neuronal activity and brain functions	10
Volatile uptake, transport, perception, and signaling shape a plant’s nose	9
Mannuronate C-5 epimerases and their use in alginate modification	9
The impact of assessment and feedback practice on the student learning experiences in higher education	9
A comparative guide to expression systems for phage lysin production	9
Evolution of SLiM-mediated hijack functions in intrinsically disordered viral proteins	9
Beyond degradation tags: How FAT10 and ubiquitin shape substrate energy landscapes	9
Does AMPK bind glycogen in skeletal muscle or is the relationship correlative?	9
Cross-linking mass spectrometry for mapping protein complex topologies in situ	8
Epigenetic impact of endocrine-disrupting chemicals on atherosclerosis	8
A special issue of Essays in Biochemistry on current educational developments in molecular bioscience	8
New molecules in plant defence against pathogens	8
Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X7R	8
Catalytic mechanism and kinetics of malate dehydrogenase	8
Interplay between phytohormone signalling pathways in plant defence – other than salicylic acid and jasmonic acid	8
Non-covalent SUMO interactions with (de)conjugation enzymes	8
Mechanisms of bioleaching: iron and sulfur oxidation by acidophilic microorganisms	8
HECT ubiquitin ligases as accessory proteins of the plant proteasome	8
Ubiquitination of the ubiquitin-binding machinery: how early ESCRT components are controlled	8