OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Medicine is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Normal Gut Microbiomes in Diverse Populations: Clinical Implications	570
Approach Toward Early Detection and Prevention of Early-Onset Colorectal Cancer	434
Clinical Phenotypes of Cystic Fibrosis Carriers	290
Carbon Monoxide Poisoning: From Microbes to Therapeutics	278
Whole Inactivated Virus and Protein-Based COVID-19 Vaccines	209
COVID-19 Vaccines: Adenoviral Vectors	165
Treatments for COVID-19	153
New Biological Therapies for Multiple Myeloma	151
Gender-Affirming Care of Transgender and Gender-Diverse Youth: Current Concepts	131
Clonal Expansion of Stem/Progenitor Cells in Cancer, Fibrotic Diseases, and Atherosclerosis, and CD47 Protection of Pathogenic Cells	129
SARS-CoV-2 Vaccination-Induced Thrombotic Thrombocytopenia: A Rare but Serious Immunologic Complication	126
Care Models for Cancer Survivors	123
Muscarinic Acetylcholine Receptor Activators as Transformative Therapeutics for Schizophrenia	119
Club Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics	113
New Therapeutic Approaches to Large-Vessel Vasculitis	102
Multispecific CAR T Cells Deprive Lymphomas of Escape via Antigen Loss	92
Cystic Fibrosis Modulator Therapies	90
Multi-Cancer Early Detection: The New Frontier in Cancer Early Detection	88
Health Effects of Wildfire Smoke Exposure	88
Spontaneous Coronary Artery Dissection: New Insights into This Not-So-Rare Condition	85
Xenotransplantation: Promises and Perils	85
Precision Approaches to Chronic Obstructive Pulmonary Disease Management	84
Exercise in Octogenarians: How Much Is Too Little?	84
Advances in Therapy for Refractory Epilepsy	71
Application and Expectations for Immune Checkpoint Blockade of LAG3 and TIGIT	70

COVID-19 and Kidney Disease	65
MELD 3.0 in Advanced Chronic Liver Disease	64
Phage Therapy for Antibiotic-Resistant Bacterial Infections	61
Clinical Perspectives on IgG4-Related Disease and Its Classification	60
Next-Generation Noninvasive Colorectal Cancer Screening	58
Sleep Health Disparities	57
Myocardial Infarction with Nonobstructive Coronary Arteries	55
Genetics of Dilated Cardiomyopathy	54
Kawasaki Disease Vasculitis: From Diagnosis to New Concepts in Pathophysiology and Therapeutic Approaches	48
	47
The Genetic Basis of Sudden Cardiac Death: From Diagnosis to Emerging Genetic Therapies	47
RASopathies in Cardiac Disease	46
The Hospitalist Movement 25 Years Later	45
Recent Advances in Osteoporosis Therapeutics	44
Update in Adult Transgender Medicine	43
Update on Hepatorenal Syndrome: From Pathophysiology to Treatment	43