OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Medicine is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Normal Gut Microbiomes in Diverse Populations: Clinical Implications	584
Approach Toward Early Detection and Prevention of Early-Onset Colorectal Cancer	444
Whole Inactivated Virus and Protein-Based COVID-19 Vaccines	305
Carbon Monoxide Poisoning: From Microbes to Therapeutics	297
Clinical Phenotypes of Cystic Fibrosis Carriers	211
COVID-19 Vaccines: Adenoviral Vectors	173
SARS-CoV-2 Vaccination-Induced Thrombotic Thrombocytopenia: A Rare but Serious Immunologic Complication	165
Treatments for COVID-19	154
New Biological Therapies for Multiple Myeloma	138
Clonal Expansion of Stem/Progenitor Cells in Cancer, Fibrotic Diseases, and Atherosclerosis, and CD47 Protection of Pathogenic Cells	129
Gender-Affirming Care of Transgender and Gender-Diverse Youth: Current Concepts	129
Muscarinic Acetylcholine Receptor Activators as Transformative Therapeutics for Schizophrenia	128
Care Models for Cancer Survivors	125
New Therapeutic Approaches to Large-Vessel Vasculitis	120
Club Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics	105
Multispecific CAR T Cells Deprive Lymphomas of Escape via Antigen Loss	98
Cystic Fibrosis Modulator Therapies	93
Health Effects of Wildfire Smoke Exposure	92
Xenotransplantation: Promises and Perils	90
Spontaneous Coronary Artery Dissection: New Insights into This Not-So-Rare Condition	89
Multi-Cancer Early Detection: The New Frontier in Cancer Early Detection	87
Exercise in Octogenarians: How Much Is Too Little?	86
Advances in Therapy for Refractory Epilepsy	84
Precision Approaches to Chronic Obstructive Pulmonary Disease Management	73
Application and Expectations for Immune Checkpoint Blockade of LAG3 and TIGIT	71

MELD 3.0 in Advanced Chronic Liver Disease	68
Clinical Perspectives on IgG4-Related Disease and Its Classification	65
Phage Therapy for Antibiotic-Resistant Bacterial Infections	62
COVID-19 and Kidney Disease	61
Genetics of Dilated Cardiomyopathy	60
Next-Generation Noninvasive Colorectal Cancer Screening	60
Myocardial Infarction with Nonobstructive Coronary Arteries	60
Sleep Health Disparities	56
Kawasaki Disease Vasculitis: From Diagnosis to New Concepts in Pathophysiology and Therapeutic Approaches	50
	49
The Genetic Basis of Sudden Cardiac Death: From Diagnosis to Emerging Genetic Therapies	49
SGLT2 Inhibitors: The Sweet Success for Kidneys	48
RASopathies in Cardiac Disease	46
The Hospitalist Movement 25 Years Later	46
Recent Advances in Osteoporosis Therapeutics	45
Update on Hepatorenal Syndrome: From Pathophysiology to Treatment	45
Update in Adult Transgender Medicine	44
SARS-CoV-2 Neutralizing Antibodies for COVID-19 Prevention and Treatment	42
Optimizing KRAS Therapeutics for Non–Small Cell Lung Cancer	41
Update on the Porphyrias	41
Effects on Cancer Prevention from the COVID-19 Pandemic	40
COVID-19 and Diabetes	39
Candida auris: Epidemiology and Antifungal Strategy	38
Approach to Therapy for Chronic Pouchitis	37
Endocrine Disorders and COVID-19	37
Emerging Technologies in Cardiac Pacing	36
Chronic Cough Hypersensitivity as a Neuropathic Disorder: Implications for Management and New Treatments	34
Progress in the Management of Pancreatic Neuroendocrine Tumors	33
Update on HIV Chemoprevention	31
A Rational Approach to the Treatment of Acute Pulmonary Embolism	30
Glucagon-Like Peptide 1 Receptor Agonists and Cardiovascular Disease	28
Advances and Applications of Polygenic Scores for Coronary Artery Disease	28
Peripheral Artery Disease: New Concepts, Treatments, and Disparities	28
A Tale of Two Checkpoints: ATR Inhibition and PD-(L)1 Blockade	27
COVID-19 Thrombotic Complications and Therapeutic Strategies	27
Adverse Impact of Cannabis on Human Health	27
Heart Failure with Preserved Ejection Fraction: Mechanisms and Treatment Strategies	27
	27
Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome	26
COVID-19: Inflammatory Profile	26
Primary Aldosteronism and the Role of Mineralocorticoid Receptor Antagonists for the Heart and Kidneys	26
Interventional Pulmonology: Extending the Breadth of Thoracic Care	26
Clonal Hematopoiesis and Its Impact on Human Health	25
What Has the Undiagnosed Diseases Network Taught Us About the Clinical Applications of Genomic Testing?	25
Wearable Devices: Implications for Precision Medicine and the Future of Health Care	25
COVID-19 Critical Illness: A Data-Driven Review	24
New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics	24
Medical Therapy Alone, Percutaneous Coronary Intervention, or Coronary Artery Bypass Grafting for Treatment of Coronary Artery Disease	23
Maternal Mortality in the United States: Trends and Opportunities for Prevention	22
New Frontiers in the Treatment of Rectal Cancer	22

Subclinical Atrial Fibrillation: A Silent Threat with Uncertain Implications	22
Long-Term Risks of Living Kidney Donation: State of the Evidence and Strategies to Resolve Knowledge Gaps	21
Therapeutic Considerations in Preventing Chronic Kidney Disease	19
Chronic Neuromuscular Respiratory Failure and Home Assisted Ventilation	17
Cytomegalovirus Therapy: Role of Letermovir in Prophylaxis and Treatment in Transplant Recipients	15
Fatty Liver Disease: Diagnosis and Stratification	15
New Oral Selective Estrogen Receptor Degraders Redefine Management of Estrogen Receptor–Positive Breast Cancer	15
Exome/Genome Sequencing in Undiagnosed Syndromes	14