OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Biochemistry is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators	171
Cullin-RING Ubiquitin Ligase Regulatory Circuits: A Quarter Century Beyond the F-Box Hypothesis	126
The Initiation of Eukaryotic DNA Replication	99
Repair of DNA Double-Strand Breaks by the Nonhomologous End Joining Pathway	83
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation	82
Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair	79
Synonymous but Not Silent: The Codon Usage Code for Gene Expression and Protein Folding	78
Chaperoning SNARE Folding and Assembly	72
The Form and Function of PIEZO2	69
Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis	64
A Natural Product Chemist's Guide to Unlocking Silent Biosynthetic Gene Clusters	63
Better, Faster, Cheaper: Recent Advances in Cryo–Electron Microscopy	57
MAPK-Activated Protein Kinases: Servant or Partner?	56
Tunnels for Protein Export from the Endoplasmic Reticulum	53
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	50
Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory	48
Repair of DNA Breaks by Break-Induced Replication	47
DNA–Protein Crosslinks and Their Resolution	42
Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol	42
Structural Mechanism of Transport of Mitochondrial Carriers	40
mRNA Regulation by RNA Modifications	40
The Proteins of mRNA Modification: Writers, Readers, and Erasers	39
Mitochondrial DNA Release in Innate Immune Signaling	38
Role of the TOM Complex in Protein Import into Mitochondria: Structural Views	37
Structural Insights Accelerate the Discovery of Opioid Alternatives	36