OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Biochemistry is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators	199
Cullin-RING Ubiquitin Ligase Regulatory Circuits: A Quarter Century Beyond the F-Box Hypothesis	139
The Initiation of Eukaryotic DNA Replication	121
Repair of DNA Double-Strand Breaks by the Nonhomologous End Joining Pathway	100
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation	90
Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair	89
Synonymous but Not Silent: The Codon Usage Code for Gene Expression and Protein Folding	89
The Form and Function of PIEZO2	78
Chaperoning SNARE Folding and Assembly	74
Better, Faster, Cheaper: Recent Advances in Cryo–Electron Microscopy	67
A Natural Product Chemist's Guide to Unlocking Silent Biosynthetic Gene Clusters	66
Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis	66
MAPK-Activated Protein Kinases: Servant or Partner?	61
The Proteins of mRNA Modification: Writers, Readers, and Erasers	55
Repair of DNA Breaks by Break-Induced Replication	55
mRNA Regulation by RNA Modifications	54
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	54
Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory	53
Tunnels for Protein Export from the Endoplasmic Reticulum	53
Mitochondrial DNA Release in Innate Immune Signaling	52
Role of the TOM Complex in Protein Import into Mitochondria: Structural Views	51
Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol	49
DNA–Protein Crosslinks and Their Resolution	48
Structural Mechanism of Transport of Mitochondrial Carriers	40
Structural Insights Accelerate the Discovery of Opioid Alternatives	38

Preparing Better Samples for Cryo–Electron Microscopy: Biochemical Challenges Do Not End with Isolation and Purification