OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Biochemistry is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Preparing Better Samples for Cryo–Electron Microscopy: Biochemical Challenges Do Not End with Isolation and Purification	296
Repair of DNA Breaks by Break-Induced Replication	182
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	170
Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis	128
Emerging Approaches for Studying Lipid Dynamics, Metabolism, and Interactions in Cells	123
Lipid Dynamics at Membrane Contact Sites	114
Chaperoning SNARE Folding and Assembly	108
The Initiation of Eukaryotic DNA Replication	101
The Purinosome: A Case Study for a Mammalian Metabolon	97
Synonymous but Not Silent: The Codon Usage Code for Gene Expression and Protein Folding	94
Moonlighting Enzymes at the Interface Between Metabolism and Epigenetics	89
The Structural Dynamics of Translation	87
Mitochondrial DNA Release in Innate Immune Signaling	87
Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol	86
Mechanisms of General Anesthesia	84
The Inseparable Relationship Between Cholesterol and Hedgehog Signaling	84
Membrane Exporters of Fluoride Ion	83
Signaling from RAS to RAF: The Molecules and Their Mechanisms	75
Emerging Chemical Diversity and Potential Applications of Enzymes in the DMSO Reductase Superfamily	69
The Form and Function of PIEZO2	69
From Bioorganic Models to Cells	66
Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair	66
Short- and Long-Term Adaptation to Altered Levels of Glucose: Fifty Years of Scientific Adventure	64
High-Resolution Single-Molecule Magnetic Tweezers	61
mRNA Regulation by RNA Modifications	57

Eukaryotic Ribosome Assembly	56
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation	54
DNA–Protein Crosslinks and Their Resolution	52
Topoisomerase Regulation of Cancer Gene Expression	52
Validating Small Molecule Chemical Probes for Biological Discovery	51
Essential Biology of Lipid Droplets	48