OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biochemistry is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators	199
Cullin-RING Ubiquitin Ligase Regulatory Circuits: A Quarter Century Beyond the F-Box Hypothesis	139
The Initiation of Eukaryotic DNA Replication	121
Repair of DNA Double-Strand Breaks by the Nonhomologous End Joining Pathway	100
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation	90
Synonymous but Not Silent: The Codon Usage Code for Gene Expression and Protein Folding	89
Mechanisms of Vertebrate DNA Interstrand Cross-Link Repair	89
The Form and Function of PIEZO2	78
Chaperoning SNARE Folding and Assembly	74
Better, Faster, Cheaper: Recent Advances in Cryo–Electron Microscopy	67
A Natural Product Chemist's Guide to Unlocking Silent Biosynthetic Gene Clusters	66
Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis	66
MAPK-Activated Protein Kinases: Servant or Partner?	61
The Proteins of mRNA Modification: Writers, Readers, and Erasers	55
Repair of DNA Breaks by Break-Induced Replication	55
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	54
mRNA Regulation by RNA Modifications	54
Tunnels for Protein Export from the Endoplasmic Reticulum	53
Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory	53
Mitochondrial DNA Release in Innate Immune Signaling	52
Role of the TOM Complex in Protein Import into Mitochondria: Structural Views	51
Posttranslational Regulation of HMG CoA Reductase, the Rate-Limiting Enzyme in Synthesis of Cholesterol	49
DNA–Protein Crosslinks and Their Resolution	48
Structural Mechanism of Transport of Mitochondrial Carriers	40
Structural Insights Accelerate the Discovery of Opioid Alternatives	38

Preparing Better Samples for Cryo–Electron Microscopy: Biochemical Challenges Do Not End with Isolation and Purification	38
Molecules from the Microbiome	37
Encapsulins	37
Structural Mechanisms for Replicating DNA in Eukaryotes	37
Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond	36
The Function, Structure, and Origins of the ER Membrane Protein Complex	35
Membrane Exporters of Fluoride Ion	34
Rubisco Function, Evolution, and Engineering	33
Transcription-Coupled Nucleotide Excision Repair and the Transcriptional Response to UV-Induced DNA Damage	32
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	31
Optobiochemistry: Genetically Encoded Control of Protein Activity by Light	31
Sensory TRP Channels in Three Dimensions	30
The Purinosome: A Case Study for a Mammalian Metabolon	29
Influence of Nonspecific Interactions on Protein Associations: Implications for Biochemistry In Vivo	29
Molecular Mechanisms of Transcription-Coupled Repair	28
Influenza Virus RNA-Dependent RNA Polymerase and the Host Transcriptional Apparatus	28
Looping the Genome with SMC Complexes	28
The Roots of Genetic Coding in Aminoacyl-tRNA Synthetase Duality	27
High-Resolution Single-Molecule Magnetic Tweezers	26
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection	26
Evolutionary Dynamics and Molecular Mechanisms of HORMA Domain Protein Signaling	26
Macrocyclization and Backbone Modification in RiPP Biosynthesis	25
PI(4,5)P₂ Clustering and Its Impact on Biological Functions	25
The Structural Dynamics of Translation	25
In Vitro Genetic Code Reprogramming for the Expansion of Usable Noncanonical Amino Acids	24
3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression	22
Metalloproteomics for Biomedical Research: Methodology and Applications	21