OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biochemistry is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	446
Emerging Approaches for Studying Lipid Dynamics, Metabolism, and Interactions in Cells	345
The Initiation of Eukaryotic DNA Replication	255
Lipid Dynamics at Membrane Contact Sites	230
The Purinosome: A Case Study for a Mammalian Metabolon	156
Moonlighting Enzymes at the Interface Between Metabolism and Epigenetics	145
DNA Damage and Replication Stress Checkpoints	143
The Structural Dynamics of Translation	135
Mitochondrial DNA Release in Innate Immune Signaling	128
Mechanisms of General Anesthesia	118
Signaling from RAS to RAF: The Molecules and Their Mechanisms	112
The Inseparable Relationship Between Cholesterol and Hedgehog Signaling	107
Emerging Chemical Diversity and Potential Applications of Enzymes in the DMSO Reductase Superfamily	102
The Human Autophagy Core Complexes	98
From Cancer, Malate–Aspartate Shuttle, RNA Replicase, and mtDNA to Trypanosomes and Back to Cancer Again	96
High-Resolution Single-Molecule Magnetic Tweezers	92
mRNA Regulation by RNA Modifications	86
Eukaryotic Ribosome Assembly	85
Endogenous Sources of Abasic Sites and Implications for DNA Replication: Mechanisms of Fork Stalling and Recovery	82
DNA–Protein Crosslinks and Their Resolution	81
Topoisomerase Regulation of Cancer Gene Expression	76
Structural Biochemistry of Muscle Contraction	73
Validating Small Molecule Chemical Probes for Biological Discovery	70
The Nicotinic Acetylcholine Receptor and Its Pentameric Homologs: Toward an Allosteric Mechanism of Signal Transduction at the Atomic Level	69
Essential Biology of Lipid Droplets	69

Membrane Protein Complexity Revealed Through Native Mass Spectrometry	68
	67
Influence of Nonspecific Interactions on Protein Associations: Implications for Biochemistry In Vivo	65
The Semantics and Mechanisms of Enhancers and Promoters: “What Is True for E. coli Is True for the Elephant, Only More So”	63
Encapsulins	59
Natural and Engineered Guide RNA–Directed Transposition with CRISPR-Associated Tn7-Like Transposons	59
Ribonucleotide Incorporation by Eukaryotic B-Family Replicases and Its Implications for Genome Stability	56
Inositol Pyrophosphates as Versatile Metabolic Messengers	56
The Story of RNA Unfolded: The Molecular Function of DEAD- and DExH-Box ATPases and Their Complex Relationship with Membraneless Organelles	56
The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues	52
Lipid Quality Control and Ferroptosis: From Concept to Mechanism	50
Mitochondrial Precursor Overaccumulation Stress	45
Looping the Genome with SMC Complexes	43
Rubisco Function, Evolution, and Engineering	42
Soluble Human Lectins at the Host–Microbe Interface	42
Inhibiting Lipopolysaccharide Biogenesis: The More You Know the Further You Go	39
Structure and Mechanism of the Lipid Flippase MurJ	37
	37
Packaging of Single-Stranded RNA in Viruses and Virus-Like Particles	35
Macrocyclization and Backbone Modification in RiPP Biosynthesis	35
Molecular Structure and Function of Zinc-Dependent Histone Deacetylases	34
Nonlytic Egress and Transmission in the Virus World	33
Sensory TRP Channels in Three Dimensions	33
MAPK-Activated Protein Kinases: Servant or Partner?	32
Eukaryotic Microproteins	31
Triumphs and Challenges of Natural Product Discovery in the Postgenomic Era	29
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection	28
Kinetic Proofreading	28
The Promoter-Proximal Pause: A Decision Point Governing RNA Polymerase II Fate	28
Cotranslational Assembly of Oligomeric Proteins	27
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	26
Cellular Repair and Removal of Protein-Damage Modifications	26
Molecular Mechanisms of Transcription-Coupled Repair	26
The Great Escape: Protein Trafficking from the Bacterial Cytosol to the Outer Membrane	25