OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biochemistry is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	436
Lipid Dynamics at Membrane Contact Sites	322
The Initiation of Eukaryotic DNA Replication	240
Emerging Approaches for Studying Lipid Dynamics, Metabolism, and Interactions in Cells	228
Moonlighting Enzymes at the Interface Between Metabolism and Epigenetics	155
Mitochondrial DNA Release in Innate Immune Signaling	141
DNA Damage and Replication Stress Checkpoints	141
The Purinosome: A Case Study for a Mammalian Metabolon	134
The Structural Dynamics of Translation	121
Mechanisms of General Anesthesia	115
The Inseparable Relationship Between Cholesterol and Hedgehog Signaling	111
Signaling from RAS to RAF: The Molecules and Their Mechanisms	106
Emerging Chemical Diversity and Potential Applications of Enzymes in the DMSO Reductase Superfamily	99
The Human Autophagy Core Complexes	96
From Cancer, Malate–Aspartate Shuttle, RNA Replicase, and mtDNA to Trypanosomes and Back to Cancer Again	93
High-Resolution Single-Molecule Magnetic Tweezers	85
Eukaryotic Ribosome Assembly	85
mRNA Regulation by RNA Modifications	83
DNA–Protein Crosslinks and Their Resolution	80
Endogenous Sources of Abasic Sites and Implications for DNA Replication: Mechanisms of Fork Stalling and Recovery	79
Topoisomerase Regulation of Cancer Gene Expression	74
Validating Small Molecule Chemical Probes for Biological Discovery	72
The Nicotinic Acetylcholine Receptor and Its Pentameric Homologs: Toward an Allosteric Mechanism of Signal Transduction at the Atomic Level	69
Structural Biochemistry of Muscle Contraction	66
Essential Biology of Lipid Droplets	66

	64
Membrane Protein Complexity Revealed Through Native Mass Spectrometry	64
Influence of Nonspecific Interactions on Protein Associations: Implications for Biochemistry In Vivo	62
The Semantics and Mechanisms of Enhancers and Promoters: “What Is True for E. coli Is True for the Elephant, Only More So”	61
Natural and Engineered Guide RNA–Directed Transposition with CRISPR-Associated Tn7-Like Transposons	58
Ribonucleotide Incorporation by Eukaryotic B-Family Replicases and Its Implications for Genome Stability	55
The Story of RNA Unfolded: The Molecular Function of DEAD- and DExH-Box ATPases and Their Complex Relationship with Membraneless Organelles	55
Lipid Quality Control and Ferroptosis: From Concept to Mechanism	54
The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues	52
Inositol Pyrophosphates as Versatile Metabolic Messengers	52
Encapsulins	50
Inhibiting Lipopolysaccharide Biogenesis: The More You Know the Further You Go	43
Mitochondrial Precursor Overaccumulation Stress	42
Soluble Human Lectins at the Host–Microbe Interface	42
Looping the Genome with SMC Complexes	40
Rubisco Function, Evolution, and Engineering	38
Macrocyclization and Backbone Modification in RiPP Biosynthesis	35
	35
Packaging of Single-Stranded RNA in Viruses and Virus-Like Particles	35
Nonlytic Egress and Transmission in the Virus World	34
Structure and Mechanism of the Lipid Flippase MurJ	32
Sensory TRP Channels in Three Dimensions	31
Molecular Structure and Function of Zinc-Dependent Histone Deacetylases	31
MAPK-Activated Protein Kinases: Servant or Partner?	30
Eukaryotic Microproteins	29
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection	28
Triumphs and Challenges of Natural Product Discovery in the Postgenomic Era	27
Kinetic Proofreading	26
Cellular Repair and Removal of Protein-Damage Modifications	26
The Promoter-Proximal Pause: A Decision Point Governing RNA Polymerase II Fate	26
Cotranslational Assembly of Oligomeric Proteins	24
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	24
Molecular Mechanisms of Transcription-Coupled Repair	24
The Great Escape: Protein Trafficking from the Bacterial Cytosol to the Outer Membrane	24