OOIR: Observatory of International Research

Papers

(The H4-Index of Mechanisms of Ageing and Development is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Phenolic acid metabolites of polyphenols act as inductors for hormesis in C. elegans	141
Insights into targeting cellular senescence with senolytic therapy: The journey from preclinical trials to clinical practice	99
Characterization of a natural model of adult mice with different rate of aging	91
Polypharmacy is differentially associated with 20-year mortality among community-dwelling elderly women and men: The Israel Glucose Intolerance, Obesity and Hypertension cohort study	90
The role of cytokines/chemokines in an aging skin immune microenvironment	86
REDD1 knockdown ameliorates endothelial cell senescence through repressing TXNIP-mediated oxidative stress	77
Impact of age and gender on glioblastoma onset, progression, and management	70
Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular basis to therapy	68
Strategies for late phase preclinical and early clinical trials of senolytics	67
Effects of exosomal miRNAs in the diagnosis and treatment of Alzheimer’s disease	66
Brain aging mechanisms with mechanical manifestations	62
Coenzyme Q10 supplementation – In ageing and disease	60
Mitochondrial microRNAs (mitomiRs) in human ageing and diseases	55
Characteristics of geriatric rehabilitation inpatients based on their frailty severity and change in frailty severity during admission: RESORT	55
Editorial Board	51
The role of mitochondria in cytokine and chemokine signalling during ageing	51
Age-related alterations and senescence of mesenchymal stromal cells: Implications for regenerative treatments of bones and joints	50
Sex differences in neuroimmunoendocrine communication. Involvement on longevity	50
Mosaic loss of Y chromosome and the association to mortality in Danish men aged 56–100 years	49
In reviewing the emerging biomarkers of human inflammatory bowel disease (IBD): Endothelial progenitor cells (EPC) and their vesicles as potential biomarkers of cardiovascular manifestations and targe	48
Molecular mechanisms and potential interventions during aging-associated sarcopenia	42
Senescence of skeletal stem cells and their contribution to age-related bone loss	37
B cells from old mice induce the generation of inflammatory T cells through metabolic pathways	37
Effect of a lifestyle intervention on telomere length: A systematic review and meta-analysis	37
Recent advances in the discovery of senolytics	36

Vascular participation in bone healing: Implications related to advancing age and morbidity	36
Piezo1 transforms mechanical stress into pro senescence signals and promotes osteoarthritis severity	36
Klotho ameliorates angiotension-II-induced endothelial senescence via restoration of autophagy by inhibiting Wnt3a/GSK-3β/mTOR signaling: A potential mechanism involved in prognostic performance of Kl	36
Editorial Board	35
Living in endemic area for infectious diseases accelerates epigenetic age	34
Artesunate delays the dysfunction of age-related intestinal epithelial barrier by mitigating endoplasmic reticulum stress/unfolded protein response	34
Decreased oxidative stress response and oxidant detoxification of skin during aging	31