OOIR: Observatory of International Research

Papers

(The median citation count of Human Pathology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Table of Contents	68
Table of Contents	68
Editorial board	58
Inside front cover - Masthead	50
A real-world study on the expression and clinical application of IMP3 immunohistochemistry in bone tumors	44
Interdisciplinary analysis of cues to triage gastric lymphoid proliferations: Role of the surgical pathologist revisited	43
ARID1A, BRG1, and INI1 deficiency in undifferentiated and dedifferentiated endometrial carcinoma: a clinicopathologic, immunohistochemical, and next-generation sequencing analysis of a case series fro	39
Gradual and synergistic correlation of tumor thickness and histological grade in penile invasive carcinomas	38
Editorial board	35
High-grade B-cell lymphoma with concurrent MYC rearrangement and 11q aberrations: clinicopathologic, cytogenetic, and molecular characterization of 4 cases	31
Editorial board	29
Information for Authors	29
Genetic validation of a TSC2 immunohistochemistry assay in TSC/mTOR-pathway altered renal tumors	27
Molecular alterations in primary and metastatic PEComa: insights from the AACR project GENIE data set	26
Tumour budding and tumour-stroma ratio in hepatocellular carcinoma	25
Inside front cover - Masthead	24
Idiopathic hyalinizing fibrosclerosis: A systemic steroid-resistant condition distinct from IgG4-related disease	24
Cutaneous vascular tumors: an updated review	23
Alpha-methylacyl-CoA racemase (AMACR) protein is upregulated in early proliferative lesions of the breast irrespective of apocrine differentiation	23
Editorial board	22
Morphologic spectrum of treatment-related changes in prostate tissue and prostate cancer: an updated review	22
Polymorphic central nervous system (CNS) immune deficiency/dysregulation-associated lymphoproliferative disorders show a uniquely aggressive clinicopathologic profile compared to their extra-CNS count	22
Three pathologic criteria for reproducible diagnosis of colonic sessile serrated lesion versus hyperplastic polyp	22
Histopathology of autoimmune bullous dermatoses: what's new?	21
The sensitivity and specificity of Claudin18.2 and MUC6 in the differential diagnosis of endocervical gastric-type glandular lesions	21

Ancillary tests for hepatobiliary neoplasms: what we know and what we need to know	21
Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: a clinicopathological and molecular study of four cases	21
Information for Authors	20
Lymphoplasmacytic lymphoma and Waldenström macroglobulinemia, a decade after the discovery of MYD88L265P	20
Mucinous tubular and spindle cell carcinoma with papillae: A report of 5 cases and comparison with 18 cases of papillary renal cell carcinoma	19
Information for Authors	19
Feasibility of two-step approach for screening NTRK fusion in two major subtypes of non-small cell lung cancer within a large cohort	19
Information for Authors	19
Inside front cover - Masthead	18
Information for Authors	18
Inside front cover - Masthead	18
Clinical and histopathologic characterization of SETD2-mutated colorectal cancer	18
Information for Authors	18
Female reproductive tract inflammatory myofibroblastic tumor (IMT): A comprehensive analysis of clinicopathological and genomic features in a case series, including the identification of SERPINE1-ALK	17
Heterogeneity or change in cell of origin in diffuse large B-cell lymphomas determined using hans algorithm	17
Reprint of: The Diagnostic and Prognostic Utility of Incorporating DAXX, ATRX, and Alternative Lengthening of Telomeres (ALT) to the Evaluation of Pancreatic Neuroendocrine Tumors (PanNETs)	17
Fluorescence in-situ hybridization assessment of spindle cell-rich testicular sex cord stromal tumors demonstrates multiple chromosomal gains across histologic subtypes	17
Cyclin D1-negative mantle cell lymphoma	17
Clinicopathological and genomic copy number variation analysis in nodular hidradenoma and hidradenocarcinoma with focus on prognostically important features	16
Severe eosinophilic gastritis is associated with peripheral eosinophilia and multi-organ involvement	16
Somatic yolk sac tumors in the urinary tract: A form of rare divergent differentiation	16
The many faces and pathologic diagnostic challenges of autoimmune hepatitis	16
Table of Contents	16
The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer	15
Editorial board	15
SALL4 expression is very rare in endometrial endometrioid and serous carcinoma	15
Cellular myofibromas with SRF fusions: clinicopathological and molecular study of 3 cases of a rare entity and a potential mimic of sarcoma	15
DDR2 expression in breast cancer is associated with blood vessel invasion, basal-like tumors, tumor associated macrophages, regulatory T cells, detection mode and prognosis	15
VHL-mutated papillary cystadenoma of the mesosalpinx with omental tumor deposits and immunophenotypic overlap with mesothelioma	15
Table of Contents	15
Epstein-Barr virus–positive small cell neuroendocrine carcinoma of the nasopharynx: A clinicopathologic study of 7 cases and literature review	15
Exploring the molecular features and genetic prognostic factors of pulmonary high-grade neuroendocrine carcinomas	15
Information for Authors	15
Drug-induced digestive tract injury: decoding some invisible offenders	15
Table of Contents	15
Different clinico-pathological and prognostic features of vulvar, vaginal, and cervical melanomas	14
HPV-related multiphenotypic sinonasal carcinoma: Clinicopathologic and immunohistochemical characterization of 3 cases with comprehensive literature review and emphasis on differential diagnosis	14
Artificial intelligence in anatomical pathology: building a strong foundation for precision medicine	14
Reprint of: Updates in 2022 on the staging of testicular germ cell tumors	14
Plasmacytoid urothelial carcinoma of the urinary bladder: A single institution experience with focus on next-generation sequencing (NGS) and PD-L1 immunohistochemistry	14
CSF3R mutated myeloid neoplasms: Beyond chronic neutrophilic leukemia	14
Prevalence and detection methodology for preliminary exploration of NTRK fusion in gastric cancer from a single-center retrospective cohort	14
Pulmonary gangliocytic paraganglioma: An under-recognized mimic of carcinoid tumor	14
Biliary pseudo tumor associated with hepatic atrophy	14
Large-scale human tissue analysis identifies Uroplakin 1b as a putative diagnostic marker in surgical pathology	14
Rhabdomyosarcoma: Updates on classification and the necessity of molecular testing beyond immunohistochemistry	13
Spectrum of histopathologic findings in risk-reducing bilateral prophylactic mastectomy in patients with and without BRCA mutations	13
Long term evaluation of optimized Gleason grading in a large cohort of men with prostate cancer in Canada	13
The molecular profile of ovarian struma ovarii	13
Editorial board	13

Molecular characterization of large cell calcifying sertoli cell tumors: A multi-institutional study of 6 benign and 2 malignant tumors	13
Editorial board	12
Smooth muscle actin-negative juxtaglomerular cell tumor: A potential diagnostic pitfall	12
Morphologic alterations post trimodal therapy in muscle-invasive urothelial carcinoma: understanding the impact of post-treatment changes on the pathological interpretation and their potential clinica	12
The effect of human immunodeficiency virus and human papillomavirus strain diversity on the progression of anal squamous intraepithelial lesions	12
Inside front cover - Masthead	12
Information for Authors	12
New insights into the adverse prognostic role of squamous differentiation in intrahepatic cholangiocarcinoma: A comprehensive analysis	12
WT1 as a myoepithelial marker: a comparative study of breast, cutaneous, and salivary gland lesions	12
Inside front cover - Masthead	12
Low-grade fibromyxoid sarcoma of the breast: genetic characterization and immunohistochemical comparison to morphologic mimics	12
Diagnostic accuracy of TRIM63 RNA-ISH in MiTF-rearranged renal cell carcinomas: Results from a 331-tumor validation cohort	11
Conventional FLCN-mutated tumor: a retrospective study of 5 cases with emphasis on diagnostic challenges	11
Histologic features of allograft livers in patients treated for rejection before biopsy	11
Clinicopathologic features and proposed grossing protocol of orchiectomy specimens performed for gender affirmation surgery	11
The expanding role of BAP1 in clear cell renal cell carcinoma	11
Adaptive immune response and PD-1/ PD-L1 status in chemotherapy treated high grade serous carcinoma is dependent on chemotherapy response score	11
TFE3-rearranged ossifying fibromyxoid tumors are uniquely negative for glycoprotein non-metastatic melanoma protein B: A study of 13 TFE3-rearranged mesenchymal tumors	11
High-grade endometrioid carcinomas with pilomatrix-like features lacking CTNNB1 Mutations: Clinicopathologic characteristics and novel molecular events	11
Pancreatic acinar metaplasia at the gastroesophageal junction is associated with protective effect against intestinal metaplasia in patients with gastroesophageal reflux disease	11
Approach for reclassification of collecting duct carcinoma and comparative histopathological analysis with SMARCB1/INI1-deficient renal cell carcinoma and fumarate hydratase-deficient renal cell carci	11
Comparative study of intra- and inter-observer variability in manual scoring of HER2 immunohistochemical stains on glass slides versus paired digital images with emphasis on the low end of the express	11
Circulating tumour DNA as a prognostic tool for surgically treated pancreatic ductal adenocarcinoma	11
Table of Contents	10
Gene expression signatures of shortened-telomere-associated fibrotic interstitial lung disease	10
Neoplastic ductal plate malformation pattern rather than von Meyenburg complexes may be an early neoplastic lesion of small duct-type intrahepatic cholangiocarcinoma	10
TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma	10
Inside front cover - Masthead	10
Clinicopathologic characterization of hormone-receptor positive, human epidermal growth factor receptor 2 Null, Ultralow, and Low breast carcinoma in the metastatic setting	10
Intestinal and liver involvement by endometrial stromal sarcoma: Expanding the differential diagnosis of mesenchymal tumors involving the GI tract	10
Inside front cover - Masthead	10
PRAME expression by immunohistochemistry and reverse transcription quantitative PCR in conjunctival melanocytic lesions—a comprehensive clinicopathologic study of 202 cases and correlation of cytogene	10
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in the adolescent and young adult population: A pediatric center experience	10
CD47 expression in classic follicular lymphoma is associated with event-free survival	10
Editorial board	10
Steatohepatitic hepatocellular Carcinoma:A new approach to classifying morphological subtypes of hepatocellular carcinoma	10
Inside front cover - Masthead	10
Prostatic adenocarcinoma identified on transurethral resection of bladder tumor: A clinicopathologic series of a diagnostically relevant potential pitfall	10
Editorial board	10
BRAF V600E gene mutation is present in primary intraosseous Rosai-Dorfman disease	10
Classic Hodgkin lymphoma: An illustrative review of select diagnostic limitations and immunomorphological challenges	10
Extra-appendiceal mucinous neoplasms: A tumour with clinicopathologic similarities to low- and high-grade appendiceal counterpart	10
IgG4-related disease of the tubular gastrointestinal tract: A rare cause of lymphoplasmacytosis, eosinophilia, and mass-forming lesions	10
Oncocytic type has distinct immunohistochemical and recurrence-free survival than other histologic types of the intraductal papillary neoplasm of the bile duct	9
TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases	9
Metastatic thyroid-like follicular renal cell carcinoma with EWSR1::PATZ1 fusion: A case report and review of the literature	9
The role of hair follicle counts and ratios in the histopathological assessment of androgenic alopecia, alopecia areata and telogen effluvium: does counting ‘count’?	9
Evaluation of nuclear pseudoinclusions, GATA3, 34βE12, and GPNMB performances in CK7 diffuse positive clear cell renal cell neoplasms	9
Editorial board	9
Investigation of NPM1 mutation frequency in cutaneous blastic plasmacytoid dendritic cell neoplasms	9
Plasmacytoid variant in Lynch syndrome-associated urothelial carcinoma	9
Exploring the spectrum of serrated epithelium encountered in inflammatory bowel disease	9
Editorial board	9
Editorial board	9
Editorial board	9
Comedonecrosis within conventional prostatic adenocarcinoma vs. intraductal carcinoma of the prostate: their clinical significance is not comparable	9
TROP2 is highly expressed in cutaneous squamous cell carcinomas and a subset of adnexal carcinomas: A potential therapeutic target with TROP2-directed antibody drug conjugates	9
Select updates in the pathology of kidney, testis, and penile cancer for 2026: Including FLCN-mutated (kidney) tumors, paratesticular mesothelial tumors, and TP53/HPV status in penile squamous cell ca	9
Hydroa vacciniforme lymphoproliferative disorder, a clinicopathologic and genetic analysis	9
Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases	9
Inside front cover - Masthead	9
Morphologic and immunohistochemical study of HPV-related cervical adenosquamous carcinoma: Reappraisal of a poorly defined entity	9
Prognostic impact of histological subtyping in triple-negative breast cancer	9
Primary pulmonary Langerhans cell histiocytosis: comprehensive clinicopathologic and molecular genetic analysis of 13 cases	8
Cathepsin protease expression in infiltrative soft tissue sarcomas: cathepsin-K correlates with infiltrative tumor growth and clinical outcomes	8
Inside front cover - Masthead	8
Elevated PSPC1 and KDM5C expression indicates poor prognosis in prostate cancer	8
Papillary renal neoplasm with reverse polarity—a comparative study with CCPRCC, OPRCC, and PRCC1	8
Information for Authors	8
Ovarian epithelioid tumor with FUS::CREM fusion and multilineage protein expression: Report of a case in the EWSR1/FUS-CREB tumor spectrum	8
Primary adenocarcinoma of the urinary tract and its precursors: Diagnostic criteria and classification	8
Panviral metagenomic sequencing provides further evidence for human papillomavirus 42 association with digital papillary adenocarcinoma	8
Mast cell neoplasm: a challenging pathological diagnosis	8
Table of Contents	8
Complex immunophenotypes: renal cell carcinoma with concurrent loss of SDHB/INI1 and FH/INI1	8
Myeloid nuclear differentiation antigen: an aid in differentiating lymphoplasmacytic lymphoma and splenic marginal zone lymphoma in bone marrow biopsies at presentation	8
Somatic-type malignancies in testicular germ cell tumors	8
Margin status in ductal carcinoma in situ of the breast: radiological-pathological correlation in slice radiographs and histological large-format slides of breast conserving surgery specimens	8
Hyalinizing trabecular tumor of the thyroid: Interest of GLIS3 immunohistochemical study to detect PAX8::GLIS3 rearrangement	8
Molecular profile of micropapillary urothelial carcinoma of the urinary bladder: An analysis of 99 cases by next-generation sequencing	8

Information for Authors	8
Corrigendum to Clinicopathological features and prognostic analysis of 247 small cell lung cancer with limited-stage after surgery [Hum Pathol 108 (2021) 84–92]	8
Leukemic phase of MYC/BCL2 double-hit high-grade B-cell lymphoma: A report of 35 cases	8
Clinicopathological, cytogenetic, and molecular profiles of primary cutaneous diffuse large B-cell lymphomas	8
PAX5 as a diagnostic tool in unconventional acute leukemia: Establishing immunohistochemical evidence of B-cell lineage	8
Beta-2-microglobulin positive tumor cells and CD8 positive lymphocytes are associated with outcome in post-neoadjuvant colorectal cancer resections	8
Nonspecific interstitial pneumonia pattern is a frequent finding in patients with post-acute COVID-19 syndrome treated with bilateral orthotopic lung transplantation: current best evidence	7
Melanocytic neoplasm with novel EPS15:BRAF fusion and congenital features	7
Practical and challenging issue in thyroid cytopathology	7
Malignant rhabdoid tumors of the vulva versus epithelioid sarcomas: a clinicopathologic, immunohistochemical, and molecular genetics study	7
Inside front cover - Masthead	7
The value of SOX2 in the differential diagnosis of SMARCA4 (BRG1)-deficient uterine neoplasms	7
Reprint of: morphologic spectrum of treatment-related changes in prostate tissue and prostate cancer: an updated review	7
Signet-ring cell sinus histiocytosis: report of the clinicopathologic characteristics of 4 cases with emphasis on the differential diagnosis of signet-ring cell lesions	7
Inside front cover - Masthead	7
Epstein-Barr virus associated gastric carcinoma: A clinicopathologic study with recognition of a distinctive reticular histologic pattern	7
Enteroblastic cholangiocarcinoma: An uncommon, underrecognized subtype of bile duct cancer	7
Reproducibility and prognostic ability of chronicity parameters in kidney biopsy – Comprehensive evaluation comparing microscopy and artificial intelligence in digital pathology	7
Clinicopathological and molecular genetic insights into EBV-positive inflammatory follicular dendritic cell sarcoma	7
Table of Contents	7
Information for Authors	7
Analysis of discordance between mismatch repair and microsatellite instability testing in endometrial cancer	7
Table of Contents	7
Inside front cover - Masthead	7
SUOX and GLUT1 are biomarkers for the prognosis in large duct type intrahepatic cholangiocarcinoma	7
Mesenchymal neoplasms of the tongue: A clinicopathologic study of 93 cases	7
Desmin immunostaining is effective for improving interobserver variability in the depth assessment of the submucosal invasion of colorectal cancers	7
Update on immunohistochemistry in bone and soft tissue tumors: Cost-effectively replacing molecular testing with immunohistochemistry	7
Paneth cell-like differentiation in a neuroendocrine tumor (NET) of the appendix. A unique case report	7
Biological and clinical perspectives of TERT promoter mutation detection on bladder cancer diagnosis and management	7
Genomic aberration detection by fluorescence in situ hybridization	7
A Comparative Evaluation of TRPS1 and GATA3 in adenoid cystic, secretory, and acinic cell carcinomas of the breast and salivary gland	7
Editorial board	7
Global vs. individual scoring when prostate needle cores from a single systematic biopsy site show Gleason score heterogeneity	7
Mixed-grade papillary urothelial carcinoma with a minor high-grade component shows a significantly worse clinical outcome than low-grade papillary urothelial carcinoma	6
Biliary adenofibroma and cholangiocarcinoma: neighbors or relatives? A systematic and critical review	6
Clinicopathological features and molecular genetic changes in 17 cases of uterine tumor resembling ovarian sex cord tumor	6
Primary cutaneous T-cell lymphoma: a review of the most common entities with focus on recent updates	6
Merkel cell carcinoma: an update	6
Prognostic significance of trophoblastic cell surface antigen 2 expression and pathologic parameters in patients with ampullary adenocarcinoma	6
Significance of mucin-suspended tumor bud-like structures in colorectal cancer	6
Inside front cover - Masthead	6
Survivin, sonic hedgehog, krüppel-like factors, and p53 pathway in serous ovarian cancer: an immunohistochemical study	6
Clinicopathologic findings in native liver biopsies after heart transplantation and total artificial heart implantation	6
Editorial board	6
Digitally assessed lymphocyte infiltration in rectal cancer biopsies is associated with pathological response to neoadjuvant therapy	6
Impact of neoadjuvant chemotherapy on PD-L1 expression in oral squamous cell carcinoma: A matched biopsy-resection study	6
Table of Contents	6
GATA3 expression in primary lung carcinomas: correlation with histopathologic features and TTF-1, napsin A, and p40 expression	6
Inside front cover - Masthead	6
Table of Contents	6
Editorial board	6
Actual encounters of the kidney kind: Exploring 48 cases of renal collision tumors through the lens of literature	6
Molecular subtype expression and genomic profiling differ between surgically resected pure and combined small cell lung carcinoma	6
Deep exploration of immune function in EGFR wild-type and mutated lung adenocarcinomas by gene expression profiling: role of TRAIL-R2 (TNFRSF10B) in patient treatment and outcome	6
Undifferentiated embryonal sarcoma of the liver: A clinicopathological and genomic study of 10 cases from a single institution	6
Inside front cover - Masthead	6
Gastrointestinal amyloidosis: an often unexpected finding with systemic implications	6
Porto-sinusoidal vascular disorder (PSVD): Survey-based analysis of the usage and drawbacks of this newly proposed terminology	6
Intracranial low-grade tumors with ALK rearrangement: diverse tumor types with shared molecular alterations	6
Estrogen receptor expression in human tumors: A tissue microarray study evaluating more than 18,000 tumors from 149 different entities	6
Loss of dystrophin is common in uterine leiomyosarcoma: a potential biomarker for clinical application	6
Selected updates in thyroid, parathyroid, and adrenal gland pathology	6
Comparison of genomic profiling of patient-matched primary colorectal and surgical resected distant metastatic (stage IV) colorectal carcinoma for drug actionability	6
Genetic alteration analysis of non-pediatric diffuse midline glioma, H3 K27-altered	6
Molecular and clinicopathological characteristics of invasive breast cancers with HER2-ultralow expression	6
Intramuscular hemangioma capillary type with HRAS mutation: Expanding the molecular genetic spectrum with an emphasis on overlap with arteriovenous malformations and distinct from infantile hemangioma	6
The emerging role of NF2 alterations in new and established subtypes of renal cell carcinoma	6
Information for Authors	6
Chromosomal aberrations, visualized using UroVysion® fluorescence in-situ hybridization assay, can predict poor prognosis in formalin-fixed paraffin-embedded tissues of cholangiocarcinoma patients	6
Dedifferentiation in bone and soft tissue sarcomas: How do we define it? What is prognostically relevant?	5
Eosinophils in metastatic melanoma	5
Table of Contents	5
Vulvar and vaginal leiomyosarcomas: Immunohistochemical, molecular genetic and MDM2 fluorescence in situ hybridization analysis of three cases	5
Genetic landscapes of breast tumors by next-generation sequencing with focus on less common types and genotype-phenotype correlations	5
Table of Contents	5
Does the presence of capsule influence prognosis in poorly differentiated thyroid carcinoma?	5
EPM2AIP1 immunohistochemistry is inadequate as a surrogate marker for MLH1 promoter hypermethylation testing in colorectal cancer	5
Centrosome dysfunction and autophagy dysregulation in renal cell carcinoma: Implications for tumor progression and therapy	5
Application of flow cytometry immunophenotypic analysis for the diagnosis of mature B-cell lymphomas/leukemias	5
Editorial board	5
Assessment of trophoblast cell-surface antigen 2 (TROP2) and nectin-4 expression in choriocarcinoma	5
Liver pathology in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: vasculopathic disease beyond nodular regenerative hyperplasia	5
EWSR1-and FUS-rearranged acute leukemias: Clinicopathological and genomic characterization	5
Clinicopathologic characterization of hepatocellular adenomas in men: a multicenter experience	5
Critical aspects of microsatellite instability testing in endometrial cancer: a comparison study	5
Application and pitfalls of immunophenotyping in challenging plasma cell neoplasms: A case series	5
Mass spectrometry–based assessment of prostate cancer–associated crystalloids reveals enrichment for growth and differentiation factor 15	5
LncRNA UCA1/miR-182-5p/MGMT axis modulates glioma cell sensitivity to temozolomide through MGMT-related DNA damage pathways	5
Risk of malignancy in PTEN-altered thyroid nodules detected on preoperative FNA molecular testing: a systematic review and meta-analysis	5
Diagnostic clues of BCL2-negative, faint, or controversial follicular lymphomas: a study of 103 cases	5
Cytomorphology, immunoprofile, and clinicopathologic correlation of metastatic prostatic carcinoma	5
Targeted RNA sequencing enhances the integrated diagnosis of bone and soft tissue tumors	5
Prognostic value of baseline peritoneal fluid cytology in 224 patients with unresectable peritoneal metastasis treated with Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)	5
SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma: Clinicopathologic and immunohistochemical study	5