OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic Chemistry is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Editorial Board	140
Biocatalytic conversion of the natural compound bergamottin into novel bioactive epoxy-derivatives using engineered cytochrome P450 BM3	119
Targeted isolation and antipyretic mechanisms of 5,7,4′-trimethoxyflavone and p-hydroxybenzoic acid from Mimosa pudica root via cell membrane-coated magnetic carbon spheres integrated with thermal shi	93
Dihydroartemisinin suppresses metastatic potential and induces apoptosis in gastric adenocarcinoma: An integrative experimental and computational analysis revealing inhibition of MMP14 and promotion o	90
Functional characterization and regioselectivity manipulation of two Benzylisoquinoline alkaloids O-methyltransferases from Stephania yunnanensis	88
Discovery of neuroprotective Agents: Potent, brain Penetrating, lipoic acid derivatives for the potential treatment of ischemic stroke by regulating oxidative stress and inflammation - a Preliminary s	83
Corrigendum to “Synthesis and broad-spectrum biocidal effect of novel gemini quaternary ammonium compounds” [Bioorg Chem. 151 (2024) 107646]	76
Development and evaluation of chitosan conjugated Isatin-linked Pyrazole derivative to target anti-inflammatory and anti-fibrotic in ethanol induced liver fibrosis using an in-vivo zebra fish model	73
Peptide inhibitors of angiotensin-I converting enzyme based on angiotensin (1–7) with selectivity for the C-terminal domain	71
2-Trifluoromethyl-2H-chromene ethers: The dual triumph of anti-inflammation and analgesia with minimal ulcer threat	70
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis	69
Synthesis and biological evaluation of novel naproxen–phenacetin triazole hybrids as promising anti-inflammatory agents with enhanced gastrointestinal tolerability	68
Mechanism-guided discovery of chromene-chalcone hybrids targeting PKM2 and microtubules for breast cancer therapy	65
Design and synthesis of novel quinoline-chalcone derivatives as dual inhibitors of tubulin polymerization and P-glycoprotein to overcome cisplatin resistance in cervical cancer	65
Ultra-fast responses NIR fluorescence chemosensor for monitoring HSO3−/SO2 and viscosity as well as its applications in real food samples and living biosystem	64
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis	62
THP as a sensor for the electrochemical detection of H2O2	61
6-C-Linked trehalose glycolipids signal through Mincle and exhibit potent adjuvant activity	59
Recent advances in nitrogen-containing heterocyclic compounds as receptor tyrosine kinase inhibitors for the treatment of cancer: Biological activity and structural activity relationship	58
2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response	58
Biocatalytic one pot three component approach: Facile synthesis, characterization, molecular modelling and hypoglycemic studies of new thiazolidinedione festooned quinoline analogues catalyzed by alka	58
Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition	57
Casuattimines A–N, fourteen new Lycopodium alkaloids from Lycopodiastrum casuarinoides with Cav3.1 channel inhibitory activity	56
Rosmarinic acid turned α-syn oligomers into non-toxic species preserving microtubules in Raw 264.7 cells	56
Novel natural scaffold as hURAT1 inhibitor identified by 3D-shape-based, docking-based virtual screening approach and biological evaluation	56

Synthesis of indomethacin thiadiazole urea derivatives and determination of GSTA4 inhibition and cytotoxic activity against colorectal carcinoma	55
Terpenoids from of Euphorbia helioscopia L. with anti-Zika virus activity	54
Construction of an AND logic gate fluorescent probe for highly efficient detection of formaldehyde and Pim-1 kinase	54
Renewable resource of sucrose with clusteroluminescence mechanism and applications	53
Discovery of oleanolic acid derivatives that inhibit tau protein phosphorylation and neuroinflammation induced by Aβ25–35 in vitro and in vivo	52
Editorial Board	52
Design, synthesis and cytotoxic evaluation of new thieno[2,3-d]pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers	52
Dihydro-β-agarofuran sesquiterpenoids from the root bark of Tripterygium wilfordii and their anti-neuroinflammatory activities	52
Mn-doped bimetallic synergistic catalysis boosts for enzymatic phosphorylation of N-Acetylglucosamine/ N-Acetylgalactosamine and their derivatives	50
Biotransformations of anthranilic acid and phthalimide to potent antihyperlipidemic alkaloids by the marine-derived fungus Scedosporium apiospermum F41-1	49
Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity against antibiotic-resi	49
seco-Sesquiterpenes and acorane-type sesquiterpenes with antiviral activity from the twigs and leaves of Illicium henryi Diels	48
Design, expression and biological evaluation of DX-88mut as a novel selective factor XIa inhibitor for antithrombosis	48
Synthesis and biological evaluation of new nicotinic acid derivatives as potential anti-inflammatory agents with enhanced gastric safety profile	47
Discovery of novel TLR4/MD-2 inhibitors: Receptor structure-based virtual screening studies and anti-inflammatory evaluation	46
Synthesis, structure and acetylcholinesterase inhibition activity of new diarylpyrazoles	46
Structural optimization and biological evaluation of ML364 based derivatives as USP2a inhibitors	46
Ethyl-4-(aryl)-6-methyl-2-(oxo/thio)-3,4-dihydro-1H-pyrimidine-5-carboxylates: Silica supported bismuth(III)triflate catalyzed synthesis and antioxidant activity	46
Efficient synthesis of artificial pharmaceutical solid-phase modules for constructing aptamer-drug conjugates	45
Rational design of new quinoline-benzimidazole scaffold bearing piperazine acetamide derivatives as antidiabetic agents	45
Engineering an (R)-selective transaminase for asymmetric synthesis of (R)-3-aminobutanol	45