OOIR: Observatory of International Research

Papers

(The H4-Index of Bioorganic Chemistry is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Water-soluble pillar[5]arene sulfo-derivatives self-assemble into biocompatible nanosystems to stabilize therapeutic proteins	218
(±)-Caryopterisines A and B, dimeric monoterpene alkaloids with unprecedented 6/5/5/5/6 pentacyclic rings scaffold from Caryopteris glutinosa	157
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma	93
Recent advancements in the quest of benzazoles as anti-Mycobacterium tuberculosis agents	90
Design, synthesis, and biological evaluation of novel thiourea derivatives as small molecule inhibitors for prostate specific membrane antigen	86
Exploration of triazole derivatives, SAR profiles, and clinical pipeline against Mycobacterium tuberculosis	84
Design, synthesis, and biological evaluation of novel FGFR1 PROTACs	84
Synthesis and biological evaluation of 4-((3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)quinoline derivatives as novel potential transforming growth factor-β type 1 receptor inhibitors for hepatoc	82
Heterologous expression of calcium-independent mesophilic α-amylase from Priestia megaterium: Immobilization on genipin-modified multi-walled carbon nanotubes and silica supports to enhance thermostab	75
Triazole derivatives inhibit the VOR complex-mediated nuclear transport of extracellular particles: Potential application in cancer and HIV-1 infection	71
Development and therapeutic potential of DNA-dependent protein kinase inhibitors	70
Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition	66
Impact of sulfur substitution on biotin binding affinity to streptavidin	66
Development of new chiral 1,2,4-triazole-3-thiones and 1,3,4-thiadiazoles with promising in vivo anticonvulsant activity targeting GABAergic system and voltage-gated sodium channels (VGSCs)	65
Aromatase inhibitors for the treatment of breast cancer: An overview (2019–2023)	63
Design and synthesis of new 2-oxoquinoxalinyl-1,2,4-triazoles as antitumor VEGFR-2 inhibitors	61
Mahanimbine isolated from Murraya koenigii inhibits P-glycoprotein involved in lung cancer chemoresistance	61
Synthesis of indole-based-thiadiazole derivatives as a potent inhibitor of α-glucosidase enzyme along with in silico study	60
Structural characteristics of a low molecular weight velvet antler protein and the anti-tumor activity on S180 tumor-bearing mice	60
Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-κB signaling pathway	60
SAR study of oxidative DIMs analogs targeting the Nur77-mediated apoptotic pathway of cancer cells	59
Multi-component forms of the 2nd generation H1 receptor antagonist drug, Bilastine and its enhanced physicochemical characteristics	59
Advancements in folate receptor targeting for anti-cancer therapy: A small molecule-drug conjugate approach	57
Recent developments of P-glycoprotein inhibitors and its structure–activity relationship (SAR) studies	57
Cholinesterase inhibitors assessment of aporphine alkaloids from Annona crassiflora and molecular docking studies	56

Novel heptafluoroisopropyl N-phenylpyrazole aryl amides containing cyanoalkyl groups: Design, synthesis, insecticidal activity, docking studies and theoretical calculations	55
Discovery of new small molecule inhibitors of the BPTF bromodomain	54
Nematocidal alkaloids from the roots of Stemona mairei (H.Lév.)K.Krause and identification of their pharmacophoric moiety	54
Editorial Board	52
Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells	52
Inhibition of staphylococcal nuclease by benzimidazole-based Ligand: Implications in DNA-Mediated entrapment and uptake of MRSA by Macrophage-like cells	52
Inhibitors of bacterial RNA polymerase transcription complex	52
Discovery of novel selective phosphodiesterase‑1 inhibitors for the treatment of acute myelogenous leukemia	52
Monoamine oxidase A and B inhibitory activities of 3,5-diphenyl-1,2,4-triazole substituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives	52
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94	51
Hybridization of amantadine with gardenamide A enhances NMDA antagonism and in vivo anti-PD effects	51
N-(3-cyano-1H-indol-5-yl)isonicotinamide and N-(3-cyano-1H-indol-5-yl)-1H-benzo[d]imidazole-5-carboxamide derivatives: Novel amide-based xanthine oxidase inhibitors	50
Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents	49
Discovery of N-arylcinnamamides as novel erythroblast enucleation inducers	49
Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy	48
Design, synthesis and biological evaluation of alkynyl-containing maleimide derivatives for the treatment of drug-resistant tuberculosis	48
Light and hydrogen peroxide dual-responsive DNA interstrand crosslink precursors with potent cytotoxicity	48
Synthesis of N-methylpyridine-chlorofuranformamide analogs as novel OPG up-regulators and inhibitors of RANKL-induced osteoclastogenesis	48
Receptor mapping using methoxy phenyl piperazine derivative: Preclinical PET imaging	47
Advanced high-affinity glycoconjugate ligands of galectins	47
Isolation and target identification of anti-renal fibrosis compounds from Cordyceps militaris	47
6-C-Linked trehalose glycolipids signal through Mincle and exhibit potent adjuvant activity	46
Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient	46
Thioether-based novel transition metal complexes: Synthesis, DNA interaction, in vitro biological assay, DFT calculations, and molecular docking studies	46