OOIR: Observatory of International Research

Papers

(The H4-Index of Toxicology and Applied Pharmacology is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Assessing the effects of silver nanoparticles on ARPE-19 cells via high-throughput phenotypic profiling with the Cell Painting assay	138
Editorial Board	79
Exploring the mechanism of baicalein on breast cancer based on network pharmacology, molecular docking and in vivo experiments	58
Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice	57
Mitochondrial iron deficiency mediated inhibition of ecdysone synthesis underlies lead (Pb) induced developmental toxicity in Drosophila melanogaster	56
Epigenetic modifications control CYP1A1 Inducibility in human and rat keratinocytes	48
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF	48
Azoospermia and multi-organ damage in juvenile rats exposed to α-Terpineol from weaning to sexual maturity	47
Clarithromycin attenuates severe steroid hyporesponsive asthma by regulating type 2/type 17 inflammation balance and inhibiting mast cell activation	47
Lonicerin protects pancreatic acinar cells from caerulein-induced apoptosis, inflammation, and ferroptosis by activating the SIRT1/GPX4 signaling pathway	45
Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses	43
Infection and disruption of placental multidrug resistance (MDR) transporters: Implications for fetal drug exposure	42
Ferritinophagy-derived iron causes protein nitration and mitochondrial dysfunction in acetaminophen-induced liver injury	41
Apigenin alleviates cancer drug Sorafenib induced multiple toxic effects in Swiss albino mice via anti-oxidative stress	38
Mitochondrial dysfunction-associated cellular senescence is partially involved in bleomycin-induced pulmonary fibrosis in mice	38
Editorial Board	37
Neuregulin 1 improved gastric motility and reduced gastric inflammation by activating the α7nAChR through the cholinergic anti-inflammatory pathway in diabetic rats	37
Cardiac toxicity from bisphenol A: Are electrophysiology and calcium handling perturbations dose-dependent?	36
Role of microbial microbes in arsenic bioaccumulation and biotransformation in mice	35
Integrated analysis of microRNA expression profiles and function network in mice testes after low dose lead exposure from early puberty	35
The therapeutic effect of hesperetin on doxorubicin-induced testicular toxicity: Potential roles of the mechanistic target of rapamycin kinase (mTOR) and dynamin-related protein 1 (DRP1)	34
Establishment of baseline profiles of 50 bile acids in preclinical toxicity species: A comprehensive assessment of translational differences and study design considerations for biomarker development	34
Liposomal methemoglobin as a potent antidote for hydrogen sulfide poisoning	32
Raddeanin A synergistically enhances the anti-tumor effect of MAP30 in multiple ways, more than promoting endosomal escape	31
The role of microRNAs in regulating cadmium-induced apoptosis by targeting Bcl-2 in IEC-6 cells	30

Integrative analysis of metabolomics and proteomics reveals mechanism of berberrubine-induced nephrotoxicity	29
Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments	28
Berberine alleviated contrast-induced acute kidney injury by mitophagy-mediated NLRP3 inflammasome inactivation in a mice model	28
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET	28