OOIR: Observatory of International Research

Papers

(The H4-Index of Toxicology and Applied Pharmacology is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	179
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET	71
Clarithromycin attenuates severe steroid hyporesponsive asthma by regulating type 2/type 17 inflammation balance and inhibiting mast cell activation	63
Curcumin induces apoptosis via downregulation of SKP2 and induction of GADD45A/CDKN1A expression through generation of ROS in cutaneous T-cell lymphoma cells	57
Azoospermia and multi-organ damage in juvenile rats exposed to α-Terpineol from weaning to sexual maturity	55
Towards translating in vitro measures of thyroid hormone system disruption to in vivo responses in the pregnant rat via a biologically based dose response (BBDR) model	55
Assessing the effects of silver nanoparticles on ARPE-19 cells via high-throughput phenotypic profiling with the Cell Painting assay	53
Editorial Board	50
Apigenin alleviates cancer drug Sorafenib induced multiple toxic effects in Swiss albino mice via anti-oxidative stress	50
Integrative analysis of metabolomics and proteomics reveals mechanism of berberrubine-induced nephrotoxicity	46
Neuregulin 1 improved gastric motility and reduced gastric inflammation by activating the α7nAChR through the cholinergic anti-inflammatory pathway in diabetic rats	43
circSHOC1-SLC25A3 promotes 2-naphthylamine-induced DNA damage in bronchial epithelial cells via activation of oxidative stress	43
Lonicerin protects pancreatic acinar cells from caerulein-induced apoptosis, inflammation, and ferroptosis by activating the SIRT1/GPX4 signaling pathway	43
Editorial Board	41
Liposomal methemoglobin as a potent antidote for hydrogen sulfide poisoning	41
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF	39
Anti-NOTCH1 therapy with OMP-52 M51 inhibits salivary adenoid cystic carcinoma by depressing epithelial-mesenchymal transition (EMT) process and inducing ferroptosis	39
Integrated analysis of microRNA expression profiles and function network in mice testes after low dose lead exposure from early puberty	38
Epigenetic modifications control CYP1A1 Inducibility in human and rat keratinocytes	38
Serum levels of IL-6/IL-10/GLDH may be early recognition markers of anti-tuberculosis drugs (ATB) -induced liver injury	35
Cardiorespiratory failure and sudden death induced by carfentanil exposure: Involvement of central mu1 opioid receptors	35
Mitochondrial iron deficiency mediated inhibition of ecdysone synthesis underlies lead (Pb) induced developmental toxicity in Drosophila melanogaster	33
Palmitic acid and lipopolysaccharide induce macrophage TNFα secretion, suppressing browning regulators and mitochondrial respiration in adipocytes	32
Ferritinophagy-derived iron causes protein nitration and mitochondrial dysfunction in acetaminophen-induced liver injury	31
Berberine alleviated contrast-induced acute kidney injury by mitophagy-mediated NLRP3 inflammasome inactivation in a mice model	30

Raddeanin A synergistically enhances the anti-tumor effect of MAP30 in multiple ways, more than promoting endosomal escape	30
Acute exercise activates hepatic Nrf2 signaling by ROS, AMPK and epinephrine to protect against acute liver injuries	30
Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice	29
Exploring the mechanism of baicalein on breast cancer based on network pharmacology, molecular docking and in vivo experiments	29
Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments	29