OOIR: Observatory of International Research

Papers

(The TQCC of Tohoku Journal of Experimental Medicine is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Sjögren’s Syndrome Presenting with Temporary Hemiplegia Mimicking Transient Ischemic Attack	46
Postreperfusion Syndrome Presenting as Posttransplant Portal Hypertension due to Prolonged Elevation of Pulmonary Vascular Resistance and the Role of Nitroglycerin in Diagnosis and Treatment: A Case R	38
Exploratory Study on the Relationship between Head and Neck Cancer and Japanese Cedar Pollinosis	34
Poor Environmental Conditions Created the Acute Health Deteriorations in Evacuation Shelters after the 2016 Kumamoto Earthquake	28
Long Noncoding RNA Solute Carrier Family 25 Member 21 Antisense RNA 1 Inhibits Cell Malignant Behaviors and Enhances Radiosensitivity of Gastric Cancer Cells by Upregulating Synuclein Gamma Expression	20
COVID-19-Related Symptoms during the SARS-CoV-2 Omicron (B.1.1.529) Variant Surge in Japan	16
The Prognosis and Immunotherapy Prediction Model of Ovarian Serous Cystadenocarcinoma Patient was Constructed Based on Cuproptosis-Related LncRNA	16
The ZIC2-Claudin-18.2 Axis Stimulates Pancreatic Cancer Progression and Metastasis via Activation of the ERK1/2 Signaling Pathway	16
AXIN1/MYC Axis Mediated the Osimertinib Resistance in EGFR Mutant Non-Small Cell Lung Cancer Cells	16
Families’ Health after the Great East Japan Earthquake: Findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study	16
Association between Maternal LDL Level during Pregnancy and Offspring LDL Level at Age 8	16
Exploratory Study of Serum Lactoferrin and Anti-Lactoferrin Antibody Concentrations in Patients with Endometriosis	14
Tweets about War, Medicine and Humanity: Do You Hear the People Tweet in Ukraine?	14
Rhamnazin Inhibits Hepatocellular Carcinoma Cell Aggressiveness in Vitro via Glutathione Peroxidase 4-Dependent Ferroptosis	14
Long-Term and Short-Interval Assessment of Self-Reported Urinary and Sexual Functions after Nerve-Sparing Radical Hysterectomy: A Prospective Cohort Study	13
Bacillus Licheniformis Capsules 1 (Live) Modulates Gut Microbiota and Enhances Immune Function in Chemotherapy Patients with Non-Small Cell Lung Cancer	12
Fondaparinux Results in Similar Pregnancy Outcomes with Lower Adverse Reaction Rates Compared to Low Molecular Weight Heparin in Chinese Recurrent Miscarriage Women	12
Efficacy of Triple and Talonavicular Arthrodesis for the Treatment of III-V Müller-Weiss Disease	12
Medical-Dental Collaboration and Interprofessional Training for Maxillofacial Diseases at Tohoku University Hospital	12
Review of Mental Health Consequences of the Great East Japan Earthquake through Long-Term Epidemiological Studies: The Shichigahama Health Promotion Project	12
MALT1 Positively Relates to T Helper 1 and T Helper 17 cells, and Serves as a Potential Biomarker for Predicting 30-Day Mortality in Stanford Type A Aortic Dissection Patients	12
An Infant Case of <i>Streptococcus Pneumoniae</i>-Associated Thrombotic Microangiopathy with Heterozygous <i>CFI</i> Mutation and <i>CFHR3-CFHR1</i> Deletion	11
Videofluoroscopic Dysphagia Scale as an Additional Indicator of Gastrostomy in Patients with Amyotrophic Lateral Sclerosis with Dysphagia	11
Effects of Liraglutide on Leptin Promoter Methylation in Ovarian Granulosa Cells of Obese Polycystic Ovary Syndrome Patients	11
Preservation of Inner Ear Function in a Case of Vestibular Fistula Caused by Cholesteatoma Using the Underwater Technique	11

Chronic Glucocorticoid Use is a Potential Risk Factor for Delayed Pancreatic Fistula after Laparoscopic Distal Pancreatectomy: A Retrospective Analysis	10
FGF21 Activates Autophagy to Ameliorate Lipid Accumulation in NAFLD	10
Yangfei Tongluo Decoction Alleviated Fibrosis and Inflammation in Post-Infectious Bronchiolitis Obliterans via Hedgehog Pathway	10
Age-Related Differences in Transient Receptor Potential Vanilloid 1 and 2 Expression Patterns in the Trigeminal Ganglion Neurons Contribute to Changes in the Palatal Mucosal Heat Pain Sensitivity	10
Efficacy and Safety of Third-Line Apatinib plus Chemotherapy in Metastatic Triple-Negative Breast Cancer Patients: A Multicenter, Retrospective, Cohort Study	9
New Dihydropyridine Derivative Attenuates NF-<i>κ</i>B Activation via Suppression of Calcium Influx in a Mouse BV-2 Microglial Cell Line	9
Effects of Low-Dose Tadalafil in a Patient with Biventricular Heart Failure: A Case Report	9
Effectiveness of Influenza Vaccination among Children in Satellite Cities of a Metropolitan Area in Tokyo, Japan during the 2014/2015-2018/2019 Season	8
Pathological Study on the Expression of Vasohibins in Peripheral Artery Disease	8
Gender Differences in Premenstrual Syndrome and Premenstrual Dysphoric Disorder Diagnosis and Treatment among Japanese Obstetricians and Gynecologists: A Cross-Sectional Study	8
Anamorelin Induced Acute Hyperglycemia in a Patient with Advanced Pancreatic Cancer and Diabetes: A Case Report	8
X-linked Alport Syndrome with Type IV Collagen <i>α</i>5 Chain Staining Revealing Normal Expression in the Glomerular Basement Membrane and Negative on Bowman’s Capsule and Distal Tubular	7
Up-Regulated MiR-20b-5p Mitigates Cell Inflammation and Apoptosis in Allergic Rhinitis via STAT3	7
Analysis of the Correlation between SLC6A4 rs1042173 Gene Polymorphisms and the Effect of Sufentanil Epidural Labor Analgesia in Pregnant Women	7
Cyanoacrylate is still an Effective Surgical strategy for Homeostasis: A Rodent Model of Liver Trauma and Evaluation of Early Wound Healing	7
Reminiscence Therapy-Engaged Care Exhibits a Pleasing Effect on Attenuating Psychological Burden and Bolstering Quality of Life in Elderly Postoperative Cervical Cancer Patients with Anxiety or Depres	7
Worsening Right Ventricular Function during Cardiac Surgery Is a Strong Predictor of Postoperative Acute Kidney Injury: A Prospective Observational Study	7
Characteristics of Human Leukocyte Antigen Class II Genes in Japanese Patients with Type 1 Diabetes and Autoimmune Thyroid Disease	7
Warming Yang Promoting Blood Circulation and Diuresis Alleviates Myocardial Damage by Inhibiting Collagen Fiber and Myocardial Fibrosis and Attenuating Mitochondria Signaling Pathway Mediated Apoptosi	7
Perinatal Care Preparedness in Kochi Prefecture for When a Nankai Trough Earthquake Occurs: Action Plans and Disaster Liaisons for Pediatrics and Perinatal Medicine	7
Three Autopsy Cases of Non-Meningococcal Waterhouse-Friderichsen Syndrome with Hypoplastic Spleen or Post-Splenectomy Status	7
Assessment of Clinicopathological Characteristics and Clinical Outcomes of Patients Who Developed Non-Muscle-Invasive Bladder Cancer After Radiotherapy for Prostate Cancer: A Retrospective Multicenter	7
Contribution of Inherited Variants to Hereditary Cancer Syndrome Predisposition	6
TRPV1 Protect against Hyperglycemia and Hyperlipidemia Induced Liver Injury via OPA1 in Diabetes	6
Prognostic Value and Oncogenic Effects of Ubiquitin-Specific Protease 43 in Lung Squamous Cell Carcinoma	6
At-Home Deaths and Regional Factors in Japan	6
Differential Expressions of ADAM28 and ADAMTSL3 in Gingival Tissue of Patients with Periodontitis	6
Prediction and Risk Factors of Lower Extremity Deep Vein Thrombosis after Total Joint Arthroplasty	6
Bipolar Radiofrequency Ablation of the Adrenal Gland: <i>In Vivo</i> and <i>Ex Vivo</i> Experiments	6
Neuromyelitis Optica Spectrum Disorder with Interstitial Pneumonia and Marked HyperCKemia as an Initial Presentation: A Case Report and Literature Review	6
Strategy of Pancreatectomies for Pancreatic Ductal Adenocarcinoma in Patients with a History of Gastrectomy	6
Association between NLRP3 Inflammasome and Tumor-Node-Metastasis Staging in Prostate Cancer: Immunohistochemical Studies of Prostate Needle Biopsy and Radical Prostatectomy Specimens	6
MiR-423-5p Inhibition Exerts Protective Effects on Angiotensin II-Induced Cardiomyocyte Hypertrophy	5
Prognostic Significance of Home and Ambulatory Blood Pressure: Summary of Longitudinal Evidence from the Ohasama Study	5
Effectiveness of Information-Motivation-Behavioral Skills Model of Hypothyroidism Self-Management Integrated into Prenatal Care in Pregnant Women with Newly Diagnosed Hypothyroidism	5
Clinical and Laboratory Differences between Delta and UK Variants of SARS-CoV-2: B.1.617.2 and B.1.1.7	5
Pediatric Intravenous Anesthesia in Japan—Where Are Anesthesiologists?	5
Expression of Periostin in Benign Salivary Gland Tumors	5
Characteristics and Death Circumstances on Emergency Admission of Older Patients Receiving Medical and Long-term Care at Home or Nursing Home: Analysis of a Nationwide Administrative Database in Japan	5
Shenqi Qiangjing Granules Ameliorate Asthenozoospermia in Mice by Regulating Ferroptosis through the METTL3/GPX4 Signaling Axis	5
Association Between the Number of Deliveries and Cognitive Impairment Considering the Presence of Subclinical Cerebrovascular Diseases: The Ohasama Study	5
Serum Extracellular Vesicles Attenuate Cardiomyocyte Injury Induced by Hypoxic/Reoxygenation by Regulating miR-1229-5p	5
Successful Total Callosotomy in a Patient with Lennox-Gastaut Syndrome and Cardio-Facio-Cutaneous Syndrome	5
Analysis of Abnormal Expression of MiR-320b in Serum of Patients with Hypertension and its Clinical Value	5
Outcomes of Chemotherapy for Advanced Esophageal Squamous Cell Carcinoma: A Study Using Real-World Data	5
Phenotypic Variability in a Family with Carney Complex Accompanied by a Novel Mutation Involving <i>PRKAR1A</i>	5
Systemic Immune-Inflammation Index Predicts Tumor Recurrence after Radical Resection for Colorectal Cancer	5
LncRNA-CR848007.6 Affects Insulin Secretion by Regulating Cell Apoptosis and DNA Damage in Cadmium-Exposed Pancreatic β Cells and is a Novel Biomarker in Patients with Diabetes	5
Predictive Value of LncRNA TUG1 for Complications after Caesarean Section with Scarred Uterus	5
Eosinophilic Duodenal Ulcer Exacerbation after <i>Helicobacter pylori</i> Eradication in a 14-Year-Old Boy	5

Lenvatinib plus Pembrolizumab Combination Therapy for Advanced or Recurrent Endometrial Cancer: A Single-Center, Retrospective Analysis	4
Comparison of Image Quality and Safety Profile between Ethiodol and Ioversol Contrast Medium for Hysterosalpingography: A Meta-Analysis	4
Pulmonary Alveolar Proteinosis-Like Pathological Changes Mimicking Lung Adenocarcinoma in Situ	4
Web-Based Post-Bereavement Survey System in Specialized Palliative Care: A Feasibility Pilot Study	4
Influence of Respiratory Gas Density on Tidal Volume during Mechanical Ventilation: A Laboratory Investigation and Observational Study in Children	4
Anteriorly Tilted Coronal CT of Paranasal Sinuses for Endoscopic Sinus Surgery	4
1,25(OH)2D3 is Involved in the Regulation of Caspase-3/GSDME Pathway-Mediated Cellular Pyroptosis on Kidneys of Rats with Diabetic Nephropathy	4
Evaluation and Comparison of Intervertebral Disc Degeneration Models Induced by Cervical Instability in Rats	4
Serum Exosomal MicroRNA-186-5p Positively Correlates with Lipid Indexes, Coronary Stenosis Degree, and Major Adverse Cardiovascular Events in Coronary Heart Disease	4
COVID-19 in a Hairy Cell Leukemia Patient: A Rare Case Report	4
Upregulation of Long Noncoding RNA MAGOH-DT Mediates TNF-<i><b>α</b></i> and High Glucose-Induced Endothelial-Mesenchymal Transition in Arteriosclerosis Obliterans	4
CircRNA CircABCB1 Diminishes the Sensitivity of Breast Cancer Cells to Docetaxel by Sponging MiR-153-3p	4
Clinical Significance of LncRNA NNT-AS1 in the Diagnosis, Deterioration and Prognosis of Sepsis	4
The Effect of CDT-Based Rehabilitation Nursing on Breast Cancer-Related Lymphedema	4
The Association of High Mobility Group Box-1 with Sepsis Susceptibility and Mortality Risk: A Meta-Analysis	4
Dexmedetomidine Possesses Neuroprotective Effects during Ischemic Stroke by Activating the AKT/mTOR Pathway	4
Isoastragaloside I Inhibits Production of Inflammatory Mediators and Matrix Metalloproteinases via the NF-κB and MAPK Pathways in IL-1β-Treated Chondrocyte	4
HSPA1B Regulates the Expression of Blood Pressure Related Genes in Human Umbilical Vein Endothelial Cells (HUVEC) and Its Mechanism	4
Comparison of Cancer Worries for Gastric Cancer by <i>Helicobacter Pylori</i> Infection Status at Health Check-Up Setting in Japan	4
Clinical Characteristics of the Controlled-Release Dinoprostone Vaginal Delivery System (PROPESS)	4
Recently Added Frameshift Mutation in Human Monkeypox Virus (hMPXV) <i>OPG191 </i>Gene	4
Diagnosing Drowning in Postmortem CT Images Using Artificial Intelligence	4
The Mental Health of Long-Term Evacuees outside Fukushima Prefecture after the Great East Japan Earthquake	4
Association of Familial Fanconi Syndrome with a Novel <i>GATM</i> Variant	4
Association of <i>hTERT</i> Gene Polymorphism and Colorectal Cancer (CRC) Risk in the Chinese Han Population	4
Study on Cellular Mechanism of Improving Inflammatory Effect of Gastrodin	4
Circulating miR-505-5p as a Diagnostic Marker for Acute Cerebral Infarction and Its Predictive Value for Clinical Outcomes After Endovascular Mechanical Thrombectomy	4
TM5614, an Inhibitor of Plasminogen Activator Inhibitor-1, Exerts an Antitumor Effect on Chronic Myeloid Leukemia	4
The Effect of Fanshi Tongfeng Fang on Hyperuricemia-Induced Apoptosis and Inflammation	4
SPARCL1 Regulates Proliferation and Angiogenesis of HUVECs Through the DLL4/NOTCH1 Pathway in Preeclampsia	4
Successful Combination of Fresh Frozen Plasma and Albumin 5% in Plasma Exchange for a Patient with Concurrent Thyroid Storm and Guillain-Barré Syndrome: A Rare Case Report	3
Long Noncoding LINC00115 Facilitates Cell Growth and Inhibits Apoptosis by Regulating the miR-4701-5p/P4HB Axis in Bladder Cancer	3
Real-Time Prediction of Medical Demand and Mental Health Status in Ukraine under Russian Invasion Using Tweet Analysis	3
Association between Low Back Pain and Neck Pain: A 3-Year Longitudinal Study Using the Data of the People after the Great East Japan Earthquake	3
Effect of Serum MiR-106a-5p on Vascular Calcification in Dialysis Patients	3
A New Method for Programmable RNA Editing Using CRISPR Effector Cas13X.1	3
The Importance of Tumor Necrosis Factor-<i>α</i>-Induced Protein-8 Like-2 in the Pathogenesis of Cervical Cancer and Preeclampsia via Regulation of Cell Invasion	3
Anti-TNF-α Treatment Improves the Live Birth Rate and Reduces the Risk of Premature Delivery in Patients with Recurrent Spontaneous Abortion	3
Handelin Reduces Ultraviolet A-Induced Photoaging by Inhibiting Reactive Oxygen Species Generation and Enhancing Autophagy	3
Inhibition of Regulator of G Protein Signaling 20 Reduces Cell Proliferation, Invasion and Migration by Activating the Hippo Pathway in Cutaneous Melanoma	3
Predictors for the Development of Hypoxia or Prolonged Acute Symptoms among Non-Hospitalized Mild-to-Moderate Patients with Coronavirus Disease 2019	3
Assessing Healthy Community Members’ Understanding of Prehabilitation	3
Diagnostic Accuracy of Liver Damage Based on Postmortem Computed Tomography Findings in High-Energy Trauma	3
Etiological Characteristics and Risk Factors of Chronic Obstructive Pulmonary Disease Combined with Infection	3
Plasma miR-21-5p and miRNA-93-5p Levels as Early Assessment Tools for In-Stent Restenosis Following Endovascular Stenting Treatment in Patients with Lower Extremity Atherosclerotic Disease	3
Therapeutic Drug Monitoring of Blood Sirolimus and Tacrolimus Concentrations for Polypharmacy Management in a Lymphangioleiomyomatosis Patient Taking Two Cytochrome P450 3A Inhibitors	3
Functional Mechanism and Clinical Implications of MiR-378a-3p in Femoral Shaft Fracture Healing Processes	3
Bilateral Upper-Extremity Hybrid Assistive Limb Treatment for GNE Myopathy	3
Enhanced Recovery after Surgery (ERAS) in Postoperative Lung Cancer Patients: A Novel Perioperative Strategy for Preventing Venous Thromboembolism and Improving Quality of Life	3
Fructus Gardenia Extract Improves Cerebral Ischemia-Reperfusion Injury via RIPK1-RIPK3-MLKL Axis	3
Childhood Tuberculosis in Mongolia: Trends and Estimates, 2010-2030	3
The Effects of Presurgical Infant Orthopedic Treatment on the Maxillary Arch, Craniofacial Form, and Lip Morphology of Patients with Unilateral Cleft Lip and Palate, Aged up to 5 Years	3
KLF5 Alleviates Excessive Autophagy-Induced Podocyte Injury by Enhancing ITCH-Mediated Ubiquitination of ACTR2	3
Disaster Pharmacists’ Support and Challenges Faced by Hospital Pharmacy Departments in the Disaster Response for the 2024 Noto Peninsula Earthquake	3
Severe Inflammatory Idiopathic Multicentric Castleman’s Disease Coexisting with Advanced Renal Cancer: A Case Report	3
Appropriate Health Management Considering the Vulnerability of Women during Disasters	3
Predictors of Treatment Response and Long-Term Outcomes in Young Children with Steroid-Dependent Nephrotic Syndrome Treated with High-Dose Mizoribine as First-Line Steroid-Sparing Agent	3
MiR-126-3p Inhibits the Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Targeting SLC7A5	3
Diagnosis of COVID-19 in Patients with Acute Pulmonary Embolism	3
Acute Adverse Events at a Mass Vaccination Site after the Third and Fourth COVID-19 Vaccinations in Japan	3
Effects of Phosphodiesterase-3 Inhibitor in the Management of Left Heart Failure in Extremely Low-Birth-Weight Infants with Simple Aortic Coarctation	3
Retraction: Clinical Value of MiR-636 in Postmenopausal Osteoporosis and Its Role in the Progression of Osteoporosis	3
Immunohistopathological Analysis of Extramedullary Hematopoiesis and Angiogenesis of Spleen in a Case of Primary Myelofibrosis with Huge Splenomegaly	3
Evolution of Pleural Solitary Fibrous Tumors Causing Severe Hypoglycemia after Exceptionally Long Asymptomatic Periods: Report of Two Surgical Cases	3
The Effects of Low-Dose Dexamethasone on Cell Kinetics, Cytokine Productivity and Natural Killer Cell Cytotoxicity in Murine Lymphoid Organs <i>in Vivo</i>	3
Sex-Difference in Olfactory Interhemispheric Malformation Caused by <i>Pax6</i> Haploinsufficiency	3
Gender Differences in the Association between Psychological Distress and Sociability among Older Adult Survivors: Cross-Sectional Survey Four Years after the 2016 Kumamoto Earthquake in Japan	3