OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Reviews is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Do hippocampal pyramidal cells respond to nonspatial stimuli?	452
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries	392
Energy metabolism design of the striated muscle cell	249
Altitude physiology then (1921) and now (2021): Meat on the bones	247
Recent insights into channelopathies	245
Degenerate neuronal and circuit mechanisms important for generating rhythmic motor patterns	238
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives	223
Folding brains: from development to disease modeling	222
The evolution of regulated cell death pathways in animals and their evasion by pathogens	214
SIRT7: the seventh key to unlocking the mystery of aging	205
Heterogeneity of glutamatergic synapses: cellular mechanisms and network consequences	199
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca²⁺ signaling	190
Climate change impacts on respiratory health: exposure, vulnerability, and risk	189
Ceramides are fuel gauges on the drive to cardiometabolic disease	182
Modulating vertebrate physiology by genomic fine-tuning of GPCR functions	172
The choroid plexus: a missing link in our understanding of brain development and function	171
Mitochondria in health, disease, and aging	132
Making a good egg: human oocyte health, aging, and in vitro development	130
Genome-wide association studies of cardiovascular disease	118
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs	118
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training	118
Mechanisms and physiological implications of cooperative gating of clustered ion channels	118
Role ofO-linkedN-acetylglucosamine protein modification in cellular (patho)physiology	113
The FGF/FGFR system in the physiopathology of the prostate gland	110
Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior	109

Mammalian copper homeostasis: physiological roles and molecular mechanisms	102
Understanding coenzyme Q	90
Multisystem physiological perspective of human frailty and its modulation by physical activity	87
Moving immune therapy forward targeting tme	81
Developmental origins of metabolic diseases	80
Evolution of the diagnostic value of “the sugar of the blood”: hitting the sweet spot to identify alterations in glucose dynamics	77
Synaptic memory and CaMKII	77
The TRP Channels Serving as Chemical-to-Electrical Signal Converter	74
Altered islet prohormone processing: a cause or consequence of diabetes?	74
Psycho-physiological foundations of human physical activity behavior and motivation: Theories, systems, mechanisms, evolution, and genetics	69
Cannabinoid treatments in epilepsy and seizure disorders	68
How development sculpts hippocampal circuits and function	67
Leveraging physiology and artificial intelligence to deliver advancements in health care	66
The role of globins in cardiovascular physiology	65
Implications of the NADase CD38 in COVID pathophysiology	65
Lung antimicrobial proteins and peptides: from host defense to therapeutic strategies	64
CD38 in the age of COVID-19: a medical perspective	61
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract	60
Determinants, maintenance, and function of organellar pH	60
The ion channels of endomembranes	59
The role of junctophilin proteins in cellular function	59
Bone metastasis: mechanisms, therapies, and biomarkers	59
Physiological roles of mammalian transmembrane adenylyl cyclase isoforms	59
Mitochondrial quality control in health and in Parkinson’s disease	59