Physiological Reviews

Papers
(The TQCC of Physiological Reviews is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries609
SIRT7: the seventh key to unlocking the mystery of aging382
Making a good egg: human oocyte health, aging, and in vitro development350
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling339
Implications of the NADase CD38 in COVID pathophysiology335
A comprehensive review of the neuroscience of ingestion: the physiological control of eating: signals, neurons, and networks273
Comparative physiological anthropogeny: exploring molecular underpinnings of distinctly human phenotypes261
Systematic reviews for basic scientists: a different beast241
Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation205
The physiopathology of brain-derived neurotrophic factor201
Metabolic adaptations in cancer progression201
Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms184
Sodium channelopathies of skeletal muscle and brain175
Rho GTPase signaling in cancer progression and dissemination172
Contribution of adaptive immunity to human COPD and experimental models of emphysema171
Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion168
Immunotherapy for atherosclerosis160
Understanding COVID-19 susceptibility and presentation based on its underlying physiology141
Mitochondrial calcium exchange in physiology and disease135
NETosis creates a link between diabetes and Long COVID128
Molecular dissection of the role of ACE2 in glucose homeostasis122
A primer on obesity-related cardiomyopathy122
The enteric nervous system117
Calcium-release channels: structure and function of IP3 receptors and ryanodine receptors116
The physiological control of eating: signals, neurons, and networks116
Complex physiology and clinical implications of time-restricted eating115
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives112
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs111
Genome-wide association studies of cardiovascular disease108
Angiocrine and Pericrine Signaling: How Endothelial Cells and Pericytes Drive Cancer Progression and Therapy Resistance105
Determinants, maintenance, and function of organellar pH101
The molecular athlete: exercise physiology from mechanisms to medals98
How development sculpts hippocampal circuits and function98
Physiological roles of mammalian transmembrane adenylyl cyclase isoforms96
Redox signaling in the pancreas in health and disease94
Bioenergetics: the evolutionary basis of progressive kidney disease93
The anterior chamber of the eye technology and its anatomical, optical, and immunological bases93
Is Notch1 a neglected vascular mechanosensor?84
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes84
Principles of odor coding in vertebrates and artificial chemosensory systems83
NADPH oxidases: redox regulation of cell homeostasis and disease82
In celebration of the 100th anniversary of Physiological Reviews78
Transforming the concept of connectivity: unveiling tunneling nanotube biology and their roles in brain development and neurodegeneration77
Wonder of wonders, miracle of miracles: the unprecedented speed of COVID-19 science76
Community-acquired bacterial coinfections and COVID-1974
Development of antifibrotic therapy for stricturing Crohn’s disease: lessons from randomized trials in other fibrotic diseases72
Physiologic mechanisms underlying polycystic kidney disease72
The elusive cephalic phase insulin response: triggers, mechanisms, and functions69
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