Physiological Reviews

Papers
(The TQCC of Physiological Reviews is 76. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling535
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries461
SIRT7: the seventh key to unlocking the mystery of aging320
Making a good egg: human oocyte health, aging, and in vitro development304
Implications of the NADase CD38 in COVID pathophysiology287
A comprehensive review of the neuroscience of ingestion: the physiological control of eating: signals, neurons, and networks282
Systematic reviews for basic scientists: a different beast275
Comparative physiological anthropogeny: exploring molecular underpinnings of distinctly human phenotypes259
Regulation and metabolic functions of mTORC1 and mTORC2254
Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation236
Sodium channelopathies of skeletal muscle and brain229
Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms210
Contribution of adaptive immunity to human COPD and experimental models of emphysema201
Rho GTPase signaling in cancer progression and dissemination185
The complexity of Alzheimer’s disease: an evolving puzzle161
Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion160
Understanding COVID-19 susceptibility and presentation based on its underlying physiology160
Brain mechanisms of insomnia: new perspectives on causes and consequences157
Mitochondrial calcium exchange in physiology and disease151
A primer on obesity-related cardiomyopathy150
NETosis creates a link between diabetes and Long COVID145
Complex physiology and clinical implications of time-restricted eating143
Calcium-release channels: structure and function of IP3 receptors and ryanodine receptors133
The physiological control of eating: signals, neurons, and networks127
The enteric nervous system116
Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior115
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives111
Genome-wide association studies of cardiovascular disease107
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs106
The molecular athlete: exercise physiology from mechanisms to medals106
How development sculpts hippocampal circuits and function95
Redox signaling in the pancreas in health and disease92
Determinants, maintenance, and function of organellar pH91
Physiological roles of mammalian transmembrane adenylyl cyclase isoforms91
Bone metastasis: mechanisms, therapies, and biomarkers89
Is Notch1 a neglected vascular mechanosensor?87
The anterior chamber of the eye technology and its anatomical, optical, and immunological bases87
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes85
Bioenergetics: the evolutionary basis of progressive kidney disease85
Principles of odor coding in vertebrates and artificial chemosensory systems83
G protein-coupled receptor-G protein interactions: a single-molecule perspective81
In celebration of the 100th anniversary of Physiological Reviews80
Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection78
Community-acquired bacterial coinfections and COVID-1977
The elusive cephalic phase insulin response: triggers, mechanisms, and functions76
Development of antifibrotic therapy for stricturing Crohn’s disease: lessons from randomized trials in other fibrotic diseases76
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