OOIR: Observatory of International Research

Papers

(The median citation count of Physiological Reviews is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Corrigendum for Lutsenko et al., volume 105, 2025, p. 441–491	540
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca²⁺ signaling	486
SIRT7: the seventh key to unlocking the mystery of aging	378
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries	323
Making a good egg: human oocyte health, aging, and in vitro development	313
Central control of gastrointestinal functions in health and disease	310
Hacking the functions of sleep: noninvasive approaches to stimulate sleep neurophysiology	271
Editorial Board	246
Systematic reviews for basic scientists: a different beast	234
Glycerolipid Cycling in Thermogenesis, Energy Homeostasis, Signaling, and Diseases	220
Comparative physiological anthropogeny: exploring molecular underpinnings of distinctly human phenotypes	217
Magnetosensation - the unsolved mystery	199
Metabolic adaptations in cancer progression	190
Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms	187
Sensing molecular carbon dioxide: a translational focus for respiratory disease	186
Programmed cell death and tissue regeneration: a link that should be resolved	186
The physiopathology of brain-derived neurotrophic factor	177
Contribution of adaptive immunity to human COPD and experimental models of emphysema	170
Understanding COVID-19 susceptibility and presentation based on its underlying physiology	167
Molecular systems, human noncoding sequence variants, and blood pressure	164
Immunotherapy for atherosclerosis	160
Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion	155
NETosis creates a link between diabetes and Long COVID	149
Molecular dissection of the role of ACE2 in glucose homeostasis	134
The enteric nervous system	134

Complex physiology and clinical implications of time-restricted eating	126
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives	124
Genome-wide association studies of cardiovascular disease	112
The human placenta and its role in reproductive outcomes revisited	111
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs	111
Angiocrine and pericrine signaling: how endothelial cells and pericytes drive cancer progression and therapy resistance	110
The molecular athlete: exercise physiology from mechanisms to medals	109
Redox signaling in the pancreas in health and disease	107
Determinants, maintenance, and function of organellar pH	105
Is Notch1 a neglected vascular mechanosensor?	101
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes	98
Bioenergetics: the evolutionary basis of progressive kidney disease	98
The anterior chamber of the eye technology and its anatomical, optical, and immunological bases	97
Recent advances in alcohol metabolism: from the gut to the brain	96
Gravity, microgravity, and artificial gravity: physiological effects, implementation, and applications	91
NADPH oxidases: redox regulation of cell homeostasis and disease	90
Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection	87
Community-acquired bacterial coinfections and COVID-19	81
Wonder of wonders, miracle of miracles: the unprecedented speed of COVID-19 science	77
Nanodomain cAMP signaling in cardiac pathophysiology: potential for developing targeted therapeutic interventions	77
AKAP Signaling: physiological and pathophysiological role and opportunities for novel therapeutic concepts	75
Physiologic mechanisms underlying polycystic kidney disease	73
The elusive cephalic phase insulin response: triggers, mechanisms, and functions	73
Mechanisms of SARS-CoV-2-associated anosmia	69
Transforming the concept of connectivity: unveiling tunneling nanotube biology and their roles in brain development and neurodegeneration	69
Pathophysiology of syncope: current concepts and their development	68
Navigating the multifaceted intricacies of the Na⁺-Cl⁻ cotransporter, a highly regulated key effector in the control of hydromineral homeostasis	67
Ca²⁺ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract	65
The physiological functions of human peroxisomes	65
Trained immunity: adaptation within innate immune mechanisms	64
Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology	63
An umbrella review of systematic reviews of the impact of wrist-worn wearables on health outcomes	63
Frontiers in the physiology of male pattern androgenetic alopecia: beyond the androgen horizon	63
Crossroads between autoimmunity and cancer: underlying mechanisms and clinical implications	62
Biomarkers of aging: from molecules and surrogates to physiology and function	62
Modulating vertebrate physiology by genomic fine-tuning of GPCR functions	58
Brain structural networks underlying language	57
Cannabinoid treatments in epilepsy and seizure disorders	57
Phosphodiesterase in heart and vessels: from physiology to diseases	56
Membrane adhesion junctions regulate airway smooth muscle phenotype and function	56
Protease-activated receptors in health and disease	55
The neurobiology of parenting and infant-evoked aggression	51
Salivary gland function, development, and regeneration	48
Human temperature regulation under heat stress in health, disease, and injury	47
Multiscale structure and function of the aortic valve apparatus	45
Deconstructing the GWAS library: next-generation GWAS	45
Hepatic glucagon action: beyond glucose mobilization	44
Mechanisms of myosin II force generation: insights from novel experimental techniques and approaches	43
Cysteine-based redox sensors in the cardiovascular system: from identification to physiology and drug discovery	43
Extracellular vesicles and the lung: from disease pathogenesis to biomarkers and treatments	42

Mesenchymal condensation in tooth development and regeneration: a focus on translational aspects of organogenesis	41
Sympathetic circuits regulating hepatic glucose metabolism: where we stand	41
Vascular mechanotransduction	39
Examining the shared etiology of psychopathology with genome-wide association studies	38
Uterine fibroids	38
Physiological basis for xenotransplantation from genetically modified pigs to humans	37
Impact of gastric emptying and small intestinal carbohydrate absorption on glycemia in health and diabetes: therapeutic implications	37
Glial cells in neuropathic pain	37
The multiple roles of salt-inducible kinases in regulating physiology	35
Windows into stress: a glimpse at emerging roles for CRH^PVN neurons	35
Lymphatic vessels in cancer	34
Mechanisms of Transcranial Magnetic Brain Stimulation	33
Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology	32
Mechanisms and physiological implications of cooperative gating of clustered ion channels	32
Acid-sensing ion channels: structure, function, pharmacology, and clinical significance	31
Corrigendum for Eisner et al., volume 103, 2023, p. 2767–2845	31
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training	31
Neuropathological links between T2DM and LOAD: systematic review and meta-analysis	30
A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise	29
Psychophysiological foundations of human physical activity behavior and motivation: theories, systems, mechanisms, evolution, and genetics	29