OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Therapeutic Potential of Cannabis, Cannabidiol, and Cannabinoid-Based Pharmaceuticals	105
Calcineurin Inhibitor Toxicity in Solid Organ Transplantation	31
LncRNA XIST Contributes to Cisplatin Resistance of Lung Cancer Cells by Promoting Cellular Glycolysis through Sponging miR-101-3p	22
N-Acetylcysteine Attenuates the Anxiety-Like Behavior and Spatial Cognition Impairment Induced by Doxorubicin and Cyclophosphamide Combination Treatment in Rats	20
Animal Models in Pharmacology: A Brief History Awarding the Nobel Prizes for Physiology or Medicine	19
Glioblastoma Multiforme: The Latest Diagnostics and Treatment Techniques	18
Protective Effects and Mechanisms of Flavonoids in Renal Ischemia-Reperfusion Injury	17
Trichostatin A Induces Autophagy in Cervical Cancer Cells by Regulating the PRMT5-STC1-TRPV6-JNK Pathway	17
Remdesivir: A Closer Look at Its Effect in COVID-19 Pandemic	16
Necrostatin-1 Analog DIMO Exerts Cardioprotective Effect against Ischemia Reperfusion Injury by Suppressing Necroptosis via Autophagic Pathway in Rats	15
Astragalus Polysaccharide Regulates miR-182/Bcl-2 Axis to Relieve Metabolic Memory through Suppressing Mitochondrial Damage-Mediated Apoptosis in Retinal Pigment Epithelial Cells	15
Curcumin and Its Analogs as Potential Epigenetic Modulators: Prevention of Diabetes and Its Complications	15
Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice	14
Treatment with Living Drugs: Pharmaceutical Aspects of CAR T Cells	12
Prostaglandins for Postpartum Hemorrhage: Pharmacology, Application, and Current Opinion	12
Quercetin and Osteoarthritis: A Mechanistic Review on the Present Documents	12
Tanshinone IIA Ameliorates Inflammation Response in Osteoarthritis via Inhibition of miR-155/FOXO3 Axis	11
Larotrectinib Response in NTRK3 Fusion-Driven Diffuse High-Grade Glioma	11
Febuxostat Attenuates the Progression of Periodontitis in Rats	10
Possible Therapeutic Potential of Cysteinyl Leukotriene Receptor Antagonist Montelukast in Treatment of SARS-CoV-2-Induced COVID-19	10
Effects of Sodium-Glucose Cotransporter 2 on Amputation Events: A Systematic Review and Meta-Analysis of Randomized-Controlled Trials	10
Research Progress on the Anticancer Molecular Mechanism of Targets Regulating Cell Autophagy	9
Activation of SIRT1 by Resveratrol Alleviates Pressure Overload-Induced Cardiac Hypertrophy via Suppression of TGF-β1 Signaling	9
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons	9
Protective Effects of <b><i>Morus nigra</i></b> and Its Phytochemicals against Hepatotoxicity: A Review of Preclinical Studies	9

Advanced Glycation End Products Induced Mitochondrial Dysfunction of Chondrocytes through Repression of AMPKα-SIRT1-PGC-1α Pathway	8
Luteolin Attenuates Diabetic Myocardial Hypertrophy by Inhibiting Proteasome Activity	8
Daphnetin Preconditioning Decreases Cardiac Injury and Susceptibility to Ventricular Arrhythmia following Ischaemia-Reperfusion through the TLR4/MyD88/NF-Κb Signalling Pathway	8
Treatment of Essential Thrombocythemia with Anagrelide Is Associated with an Increased Risk of Worsened Kidney Function	8
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer	7
Comparative Efficacy and Safety of Janus Kinase Inhibitors and Secukinumab in Patients with Active Ankylosing Spondylitis: A Systematic Review and Meta-Analysis	7
Comparative Efficacy and Safety of Thrombolytic Agents for Pulmonary Embolism: A Bayesian Network Meta-Analysis	7
Sufentanil Disposition and Pharmacokinetic Model-Based Dosage Regimen for Sufentanil in Ventilated Full-Term Neonates	7
Astilbin Protects Against Carbon Tetrachloride-Induced Liver Fibrosis in Rats	7
Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate	7
Utilizing Artificial Intelligence to Manage COVID-19 Scientific Evidence Torrent with Risklick AI: A Critical Tool for Pharmacology and Therapy Development	7
Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver	7
Cholestasis-Associated Pulmonary Inflammation, Oxidative Stress, and Tissue Fibrosis: The Protective Role of the Biogenic Amine Agmatine	7
A New Potential Antidepressant: Dexmedetomidine Alleviates Neuropathic Pain-Induced Depression by Increasing Neurogenesis in the Hippocampus	6
Dexrazoxane Alleviated Doxorubicin-Induced Nephropathy in Rats	6
Apatinib Inhibits Angiogenesis in Intrahepatic Cholangiocarcinoma by Regulating the Vascular Endothelial Growth Factor Receptor-2/Signal Transducer and Activator of Transcription Factor 3/Hypoxia Indu	6
Dexmedetomidine Attenuates Hypoxia/Reoxygenation Injury of H9C2 Myocardial Cells by Upregulating miR-146a Expression via the MAPK Signal Pathway	6
Asperulosidic Acid, a Bioactive Iridoid, Alleviates Placental Oxidative Stress and Inflammatory Responses in Gestational Diabetes Mellitus by Suppressing NF-κB and MAPK Signaling Pathways	6
Trimetazidine Protects from Mercury-Induced Kidney Injury	6
Association between Patients’ Knowledge and Adherence to Anticoagulants, and Its Effect on Coagulation Control	6
Validation of Fenoterol to Study β<sub>2</sub>-Adrenoceptor Function in the Rat Urinary Bladder	6
Curcumin Affects Leptin-Induced Expression of Methionine Adenosyltransferase 2A in Hepatic Stellate Cells by Inhibition of JNK Signaling	5
Beta-Sitosterol Modulates the Migration of Vascular Smooth Muscle Cells via the PPARG/AMPK/mTOR Pathway	5
A Quantitative Systems Pharmacology Framework for Optimal Doxorubicin Granulocyte Colony-Stimulating Factor Regimens in Triple-Negative Breast Cancer	5
Fenretinide Reduces Intestinal Mucin-2-Positive Goblet Cells in Chronic Alcohol Abuse	5
Docosahexaenoic Acid Attenuates the Progression of Nonalcoholic Steatohepatitis by Suppressing the Adipocyte Inflammation via the G Protein-Coupled Receptor 120/Free Fatty Acid Receptor 4 Pathway	5
Comparative Efficacy and Safety of Biological Agents in the Treatment of Lupus Nephritis: A Network Meta-Analysis	5
Cobimetinib Sensitizes Cervical Cancer to Paclitaxel via Suppressing Paclitaxel-Induced ERK Activation	5
Comparing the Effects of Febuxostat and Allopurinol in an Animal Model of Metabolic Syndrome	5
Canagliflozin Improves Liver Function in Rats by Upregulating Asparagine Synthetase	5
Angelica acutiloba Exerts Antihypertensive Effect and Improves Insulin Resistance in Spontaneously Hypertensive Rats Fed with a High-Fat Diet	5
Schisandrin B Protects against Acute Ethanol-Induced Cardiac Injury by Downregulating Autophagy via the NOX4/ROS Pathway	5
Alkaloids in Withania somnifera (L.) Dunal Root Extract Contribute to Its Anti-Inflammatory Activity	5
Physical and Chemical Compatibility of Etomidate and Propofol Injectable Emulsions	5
Quercetin Alleviates Asthma-Induced Airway Inflammation and Remodeling through Downregulating Periostin via Blocking TGF‐β1/Smad Pathway	5
Transporters, <b><i>TBC1D4</i></b>, and <b><i>ARID5B</i></b> Variants to Explain Glycated Hemoglobin Variability in Patients with Type 2 Diabetes	5
Astragaloside IV Alleviates Atorvastatin-Induced Hepatotoxicity via AMPK/SIRT1 Pathway	5
Efficacy of Icotinib, an EGFR Tyrosine Kinase Inhibitor in Non-Small Cell Lung Cancer Patients with Exon 19 Deletion and Exon 21 L858R: A Retrospective Analysis in China	4
Tigecycline-Associated Coagulopathy: A Single-Center Retrospective Analysis	4
The Efficacy and Safety of Botulinum Toxin Type A Injections in Improving Facial Scars: A Systematic Review and Meta-Analysis	4
<b><i>Rauwolfia vomitoria</i></b> Extract Represses Colorectal Cancer Cell Autophagy and Promotes Apoptosis	4
MTX Treatment Does Not Improve Outcome in Mice with AMI	4
Antibody and Cellular-Based Therapies for Pediatric Acute Lymphoblastic Leukemia: Mechanisms and Prospects	4
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway	4
Actein Antagonizes Oral Squamous Cell Carcinoma Proliferation through Activating FoxO1	4
Metformin’s Role in Hyperlactatemia and Lactic Acidosis in ICU Patients: A Systematic Review	4
The Role of Kynurenines Produced by Indolamine-2,3-Dioxygenase 1 in Sepsis	4
Toward Interprofessional Education of Pharmacogenomics: An Interdisciplinary Assessment	4
Population Pharmacokinetic Modeling to Inform Sertraline Dosing Optimization in Patients with Depression	4
Assessment of Drug Interactions with Online Electronic Checkers in Multi-Pathological Patients	4

Osimertinib in the Treatment of EGFR Mutation-Positive Advanced Non-Small Cell Lung Cancer: A Meta-Analysis