OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacological Reviews is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Seventy-Five Years of Interactions: The Department of Physiology and Pharmacology at Karolinska Institutet and Pharmacological Reviews	667
Table of Contents	446
Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review	268
INNOVATIVE THERAPEUTICS FOR RENOPROTECTION: WHERE WE ARE	232
Neurobiological Mechanisms of Nicotine Reward and Aversion	151
The Role of G Protein–Coupled Receptors and Receptor Kinases in Pancreatic β-Cell Function and Diabetes	118
The Myc Family and the Metastasis Suppressor NDRG1: Targeting Key Molecular Interactions with Innovative Therapeutics	105
L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence	101
The Nitrogen Mustards	97
Editorial Board	93
Review of Natural Language Processing in Pharmacology	90
Therapeutic advantage of combinatorial chimeric antigen receptor T cell and chemotherapies	89
Table of Contents	88
Table of Contents	87
Carbonic anhydrase inhibitors: “Old” drugs with new potential in unexpected areas	86
Table of Contents	81
Optical Approaches for Investigating Neuromodulation and G Protein–Coupled Receptor Signaling	80
Innovation in cancer pharmacotherapy through integrative consideration of germline and tumor genomes	76
Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins	74
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023	72
Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review	70
Pharmacological Modulation of the Crosstalk between Aberrant Janus Kinase Signaling and Epigenetic Modifiers of the Histone Deacetylase Family to Treat Cancer	63
The Hippo pathway: Organ size control and beyond	62
Table of Contents	61
Carbon Monoxide Signaling: Examining Its Engagement with Various Molecular Targets in the Context of Binding Affinity, Concentration, and Biologic Response	59

G Protein-Coupled Receptor Pharmacology—Insights from Mass Spectrometry	59
Asthma Therapeutics: Past, Present, and Future	59
Therapeutic Potential of Targeting Prokineticin Receptors in Diseases	59
Roles of Individual Human Cytochrome P450 Enzymes in Drug Metabolism	56
Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications	55
Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease	53
Nonhormonal Male Contraceptive Development—Strategies for Progress	52
Sulfotransferase 2B1b, Sterol Sulfonation, and Disease	51
Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?	47
Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood	47
Corrigendum to “International Union of Basic and Clinical Pharmacology. CXIX. Fundamental insights and clinical relevance regarding the carnitine palmitoyltransferase family of enzymes” [Pharmacologic	46
Opportunities for Nitric Oxide in Potentiating Cancer Immunotherapy	44
Neurobiology of the incubation of drug craving: An update	44
Dopamine, Immunity, and Disease	42
Editorial Board	41
Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease	40
Pharmacological Reviews’ 75th Year Anniversary: Past and Future—Editorial	39
Extracellular Vesicle Heterogeneity and Its Impact for Regenerative Medicine Applications	39
Analgesic Potential of Terpenes Derived from Cannabis sativa	39
Heme-thiolate monooxygenase cytochrome P450 1B1, an old dog with many new tricks	37
Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting	36
Post-Traumatic Epilepsy and Comorbidities: Advanced Models, Molecular Mechanisms, Biomarkers, and Novel Therapeutic Interventions	35
Conotoxins Targeting Voltage-Gated Sodium Ion Channels	34
Effects of Medications on Heat Loss Capacity in Chronic Disease Patients: Health Implications Amidst Global Warming	33
Vitamin D and its analogs in immune system regulation	33
Animal Behavior in Psychedelic Research	32
Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines	32
The Development of Cannabinoids as Therapeutic Agents in the United States	30
Pharmacological strategies to bridge the gap between cancer and cardiovascular therapeutics	29
Table of Contents	28
Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity	26
Editorial Board	26
International Union of Basic and Clinical Pharmacology. CXVIII. Update on the nomenclature for atypical chemokine receptors, including ACKR5	24
Potassium Channels in Parkinson’s Disease: Potential Roles in Its Pathogenesis and Innovative Molecular Targets for Treatment	23
Drugging dancing protein clouds: A close look at disorder-based drug design	23