OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacological Reviews is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies	360
Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options	358
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels	234
Is Oxytocin “Nature’s Medicine”?	191
RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges	186
Rescuing the Last-Line Polymyxins: Achievements and Challenges	167
Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development	156
Subcellular Organization of the cAMP Signaling Pathway	141
The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway	130
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function	127
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials	108
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms	106
Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics	97
Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology	93
Pharmacological Inhibition of the Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome with MCC950	87
Post-Translational Modifications of G Protein–Coupled Receptors Control Cellular Signaling Dynamics in Space and Time	85
Sex- and Gender-Based Pharmacological Response to Drugs	81
On the Clinical Pharmacology of Reactive Oxygen Species	70
Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review	68
International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update	65
Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?	62
Mutations in G Protein–Coupled Receptors: Mechanisms, Pathophysiology and Potential Therapeutic Approaches	60
Unlocking G-Quadruplexes as Antiviral Targets	60
Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species	60
Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review	59

Sex Differences in the Epilepsies and Associated Comorbidities: Implications for Use and Development of Pharmacotherapies	58
E1 Enzymes as Therapeutic Targets in Cancer	58
International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function	58
Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications	54
Aldo-Keto Reductases and Cancer Drug Resistance	52
Strategies to Modulate MicroRNA Functions for the Treatment of Cancer or Organ Injury	44
Dopamine, Immunity, and Disease	44
Inhaled Medicines: Past, Present, and Future	44
Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors	41
Nonantimicrobial Actions of Macrolides: Overview and Perspectives for Future Development	39
Therapeutics in the Pipeline Targetingα-Synuclein for Parkinson's Disease	38
Neurobiological Mechanisms of Nicotine Reward and Aversion	37
Aiding and Abetting Anhedonia: Impact of Inflammation on the Brain and Pharmacological Implications	37