Pharmacological Reviews

(The TQCC of Pharmacological Reviews is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies360
Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options358
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels234
Is Oxytocin “Nature’s Medicine”?191
RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges186
Rescuing the Last-Line Polymyxins: Achievements and Challenges167
Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development156
Subcellular Organization of the cAMP Signaling Pathway141
The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway130
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function127
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials108
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms106
Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics97
Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology93
Pharmacological Inhibition of the Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome with MCC95087
Post-Translational Modifications of G Protein–Coupled Receptors Control Cellular Signaling Dynamics in Space and Time85
Sex- and Gender-Based Pharmacological Response to Drugs81
On the Clinical Pharmacology of Reactive Oxygen Species70
Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review68
International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update65
Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?62
Mutations in G Protein–Coupled Receptors: Mechanisms, Pathophysiology and Potential Therapeutic Approaches60
Unlocking G-Quadruplexes as Antiviral Targets60
Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species60
Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review59
Sex Differences in the Epilepsies and Associated Comorbidities: Implications for Use and Development of Pharmacotherapies58
E1 Enzymes as Therapeutic Targets in Cancer58
International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function58
Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications54
Aldo-Keto Reductases and Cancer Drug Resistance52
Strategies to Modulate MicroRNA Functions for the Treatment of Cancer or Organ Injury44
Dopamine, Immunity, and Disease44
Inhaled Medicines: Past, Present, and Future44
Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors41
Nonantimicrobial Actions of Macrolides: Overview and Perspectives for Future Development39
Therapeutics in the Pipeline Targetingα-Synuclein for Parkinson's Disease38
Neurobiological Mechanisms of Nicotine Reward and Aversion37
Aiding and Abetting Anhedonia: Impact of Inflammation on the Brain and Pharmacological Implications37