European Journal of Clinical Pharmacology

Article	Citations
Therapeutic drug monitoring of oral targeted antineoplastic drugs	125
Global prevalence and types of complementary and alternative medicines use amongst adults with diabetes: systematic review and meta-analysis	52
Proton pump inhibitor use: systematic review of global trends and practices	42
A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9	37
Ivy leaf (Hedera helix) for acute upper respiratory tract infections: an updated systematic review	31
Pharmacotherapy of Alzheimer’s disease: an overview of systematic reviews	30
Predisposing factors for the development of diabetic ketoacidosis with lower than anticipated glucose levels in type 2 diabetes patients on SGLT2-inhibitors: a review	30
Safety and efficacy of tolcapone in Parkinson’s disease: systematic review	29
A real or apparent decrease in glomerular filtration rate in patients using olaparib?	26
Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19	25
Prevalence, contributory factors and severity of medication errors associated with direct-acting oral anticoagulants in adult patients: a systematic review and meta-analysis	23
Selective serotonin reuptake inhibitors in the treatment of depression, anxiety, and post-traumatic stress disorder in substance use disorders: a Bayesian meta-analysis	22
The effect of tocilizumab on mortality in hospitalized patients with COVID-19: a meta-analysis of randomized controlled trials	21
Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies	21
Improving medication adherence and effective prescribing through a patient-centered prescription model in patients with multimorbidity	20
Trends in the use of oral anticoagulants, antiplatelets and statins in four European countries: a population-based study	20
Effect of SAcubitril/Valsartan on left vEntricular ejection fraction and on the potential indication for Implantable Cardioverter Defibrillator in primary prevention: the SAVE-ICD study	19
Second-generation antipsychotic use during pregnancy and risk of congenital malformations	19
Use of ketamine and esketamine for depression: an overview of systematic reviews with meta-analyses	19
Medication-related adverse events in health care—what have we learned? A narrative overview of the current knowledge	19
The safety of systemic Janus kinase inhibitors in atopic dermatitis: a systematic review and network meta-analysis	18
Pharmacoepidemiological methods for computing the duration of pharmacological prescriptions using secondary data sources	17
REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors (REMEDI[e]S): French implicit and explicit criteria	17
Sertraline concentrations in pregnant women are steady and the drug transfer to their infants is low	16
Loncastuximab tesirine: an effective therapy for relapsed or refractory diffuse large B-cell lymphoma	15

Hospitalizations and deaths related to adverse drug events worldwide: Systematic review of studies with national coverage	15
Does aspirin have an effect on risk of death in patients with COVID-19? A meta-analysis	15
Safety profile of COVID-19 drugs in a real clinical setting	15
Who gets prescriptions for proton pump inhibitors and why? A drug-utilization study with claims data in Bavaria, Germany, 2010–2018	14
Drug utilisation in neonatal units in England and Wales: a national cohort study	14
Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies	14
Association between newly initiated thiazide diuretics and hospitalization due to hyponatremia	14
Influence of N-acetyltransferase 2 (NAT2) genotype/single nucleotide polymorphisms on clearance of isoniazid in tuberculosis patients: a systematic review of population pharmacokinetic models	14
JAK inhibitors and risk of major cardiovascular events or venous thromboembolism: a self-controlled case series study	14
Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review	13
An open-label, positron emission tomography study of the striatal D2/D3 receptor occupancy and pharmacokinetics of single-dose oral brexpiprazole in healthy participants	13
Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis	13
The effect of concomitant use of proton pump inhibitors with CDK 4/6 inhibitors on survival in metastatic breast cancer	13
Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial	13
Why hospital-based healthcare professionals do not report adverse drug reactions: a mixed methods study using the Theoretical Domains Framework	13
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed	13
Incremental net benefit of lipid-lowering therapy with PCSK9 inhibitors: a systematic review and meta-analysis of cost-utility studies	12
The effects of trazodone on human cognition: a systematic review	12
Effectiveness of palonosetron versus granisetron in preventing chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis	12
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range	12
Plasma levels of direct oral anticoagulants in atrial fibrillation patients at the time of embolic stroke: a pilot prospective multicenter study	12
Low- vs high-dose ARNI effects on clinical status, exercise performance and cardiac function in real-life HFrEF patients	12
External evaluation of published population pharmacokinetic models of polymyxin B	12
Serum concentrations of antidepressants, antipsychotics, and antiepileptics over the bariatric surgery procedure	12
Aspirin in people with dementia, long-term benefits, and harms: a systematic review	12
Direct oral anticoagulant safety during breastfeeding: a narrative review	12
Evaluation of drug-drug interactions of pemigatinib in healthy participants	11
Effect of a proton-pump inhibitor on intestinal microbiota in patients taking low-dose aspirin	11
Prevalence and clinical predictors of inappropriate direct oral anticoagulant dosage in octagenarians with atrial fibrillation	11
Intravenous lidocaine vs. NSAIDs for migraine attack in the ED: a prospective, randomized, double-blind study	11
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis	11
Association between glucagon-like peptide-1 receptor gene polymorphism and treatment response to GLP1R agonists in Chinese patients with type 2 diabetes: a prospective cohort study	11
Daridorexant for the treatment of insomnia disorder: findings and implications	11
Loss of function polymorphisms in SLCO1B1 (c.521T>C, rs4149056) and ABCG2 (c.421C>A, rs2231142) genes are associated with adverse events of rosuvastatin: a case–control study	11
Adverse drug reaction management in hospital settings: review on practice variations, quality indicators and education focus	11
Hypertension and Covid-19 vaccines: are there any differences between the different vaccines? A safety signal	10
Uptake of biosimilar trastuzumab in Denmark compared with other European countries: a comparative study and discussion of factors influencing implementation and uptake of biosimilars	10
Incidence, preventability, and causality of adverse drug reactions at a university hospital emergency department	10
Trends in use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) in Australia in the era of increased evidence of their cardiovascular benef	10
Influence of formulation and route of administration on ketamine’s safety and tolerability: systematic review	10
Hydrochlorothiazide use is associated with the risk of cutaneous and lip squamous cell carcinoma: A systematic review and meta-analysis	10
Silymarin as a preventive or therapeutic measure for chemotherapy and radiotherapy-induced adverse reactions: a comprehensive review of preclinical and clinical data	10
Trends and patterns in EU(7)-PIM prescribing to elderly patients in Germany	10
Strategies to prevent drug incompatibility during simultaneous multi-drug infusion in intensive care units: a literature review	10
Implementation and management outcomes of pharmacogenetic CYP2C19 testing for clopidogrel therapy in clinical practice	10
Selective serotonin reuptake inhibitor (SSRI) antidepressants reduce COVID-19 infection: prospects for use	10
Potentially inappropriate medication in acute hospitalized elderly patients with polypharmacy: an observational study comparing PRISCUS, STOPP, and Beers criteria	9
Effectiveness and safety of vonoprazan-based regimens compared with those of proton pump inhibitor (PPI)–based regimens as first-line agents for Helicobacter pylori: a meta-analysis of randomized clin	9
ChatGPT for generating multiple-choice questions: Evidence on the use of artificial intelligence in automatic item generation for a rational pharmacotherapy exam	9
Linezolid-associated serotonin toxicity: a systematic review	9

Non-steroidal anti-inflammatory drug-associated acute kidney injury: does short-term NSAID use pose a risk in hospitalized patients?	9
Dasiglucagon: an effective medicine for severe hypoglycemia	9
Potentially inappropriate prescribing in older hospitalized Dutch patients according to the STOPP/START criteria v2: a longitudinal study	9
Evaluating the safety and efficacy of daprodustat for anemia of chronic kidney disease: a meta-analysis of randomized clinical trials	9
Correlation between single-nucleotide polymorphisms and statin-induced myopathy: a mixed-effects model meta-analysis	9
Maternal non-steroidal anti-inflammatory drug exposure during pregnancy and risk of miscarriage: a systematic review and meta-analysis	9
Incidence risk of PD-1/PD-L1–related pneumonia and diarrhea in non-small cell lung cancer (NSCLC) patients: a systematic review and meta-analysis of randomized controlled trials	9
A case series of the rifampin-warfarin drug interaction: focus on practical warfarin management	9
Case series of chronic spontaneous urticaria following COVID-19 vaccines: an unusual skin manifestation	9
Impact of changes in controlled drugs legislation on benzodiazepine receptor agonist prescribing in Ireland: a repeated cross-sectional study	9
Population pharmacokinetics of unbound valproic acid in pediatric epilepsy patients in China: a protein binding model	9
Investigation of pharmacokinetic and clinical outcomes of various meropenem regimens in patients with ventilator-associated pneumonia and augmented renal clearance	8
Evaluation of pharmacological interventions in the management of adenomyosis: a systematic review	8
Adjuvant use of melatonin for pain management in dysmenorrhea — a randomized double-blinded, placebo-controlled trial	8
Effects of antidepressant drug therapy with or without physical exercise on inflammatory biomarkers in major depressive disorder: a systematic review and meta-analysis of randomized controlled trials	8
Colorectal cancer chemotherapy: can sex-specific disparities impact on drug toxicities?	8
Potentially inappropriate medication use and the hospitalization rate among Thai elderly patients: a retrospective cohort study	8
External evaluation of population pharmacokinetic models for voriconazole in Chinese adult patients with hematological malignancy	8
Successful deprescribing of proton pump inhibitors with a patient-centered process: the DESPIBP Project	8
Comparing the clinical outcomes across different sodium/glucose cotransporter 2 (SGLT2) inhibitors in heart failure patients: a systematic review and network meta-analysis of randomized controlled tri	8
Pharmacokinetics of cannabichromene in a medical cannabis product also containing cannabidiol and Δ9-tetrahydrocannabinol: a pilot study	8
Safety profile of chimeric antigen receptor T-cell immunotherapies (CAR-T) in clinical practice	8
Population pharmacokinetics of valproic acid in adult Chinese patients with bipolar disorder	8
The comparative impact among different intensive statins and combination therapies with niacin/ezetimibe on carotid intima-media thickness: a systematic review, traditional meta-analysis, and network	8
Coadministration of tizanidine and ciprofloxacin: a retrospective analysis of the WHO pharmacovigilance database	8
Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review	8
Effect of GLP-1R rs2254336 and rs3765467 polymorphisms on gastrointestinal adverse reactions in type 2 diabetes patients treated with liraglutide	8
Waivers of informed consent in research with competent participants and the Declaration of Helsinki	8
Feasibility study and evaluation of expert opinion on the semi-automated meta-analysis and the conventional meta-analysis	8
Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-control	8
Pharmacogenetics of tamoxifen therapy in Asian populations: from genetic polymorphism to clinical outcomes	8
Efficacy of high-dose atorvastatin or rosuvastatin loading in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a meta-analysis of randomized controlled trials with	8
DRESS characteristics according to the causative medication	8
Linezolid pharmacokinetics: a systematic review for the best clinical practice	8
Paracetamol overdose in the newborn and infant: a life-threatening event	7
Clinical non-effectiveness of clopidogrel use for peripheral artery disease in patients with CYP2C19 polymorphisms: a systematic review	7
Physiologically based pharmacokinetic combined BTK occupancy modeling for optimal dosing regimen prediction of acalabrutinib in patients alone, with different CYP3A4 variants, co-administered with CYP	7
Direct oral anticoagulants versus warfarin in nonvalvular atrial fibrillation patients with prior gastrointestinal bleeding: a network meta-analysis of real-world data	7
EurOP2E – the European Open Platform for Prescribing Education, a consensus study among clinical pharmacology and therapeutics teachers	7
Remdesivir treatment and clinical outcome in non-severe hospitalized COVID-19 patients: a propensity score matching multicenter Italian hospital experience	7
Antimicrobial stewardship: can we add pharmacovigilance networks to the toolbox?	7
Real-world comparison of fidaxomicin versus vancomycin or metronidazole in the treatment of Clostridium difficile infection: a systematic review and meta-analysis	7
Comparison of statins for primary prevention of cardiovascular disease and persistent physical disability in older adults	7
Effects of pirenzepine on vonoprazan-induced gastric acid inhibition and hypergastrinemia	7
Safety of COVID-19 vaccines in pregnancy: a VAERS based analysis	7
CYP3A5 and PPARA genetic variants are associated with low trough concentration to dose ratio of tacrolimus in kidney transplant recipients	7
Drug-related deaths among inpatients: a meta-analysis	7
Evaluation of Global trigger tool as a medication safety tool for adverse drug event detection—a cross-sectional study in a tertiary hospital	7
The European Prescribing Exam: assessing whether European medical students can prescribe rationally and safely	7
Applying pharmacokinetic/pharmacodynamic measurements for linezolid in critically ill patients: optimizing efficacy and reducing resistance occurrence	7
Cardiovascular safety of long-term anti-obesity drugs in subjects with overweight or obesity: a systematic review and meta-analysis	7
Arrhythmias related to antipsychotics and antidepressants: an analysis of the summaries of product characteristics of original products approved in Germany	7
Impact of age and gender on paliperidone exposure in patients after administration of long-acting injectable formulations—an observational study using blood samples from 1223 patients	6
Costs associated with adverse drug reactions in an older population admitted to hospital: a prospective cohort study	6
Aspirin for the prevention of hepatocellular carcinoma: an updated meta-analysis with particular focus on patients with chronic liver disease	6
Feasibility and usability of a mobile health tool on anticoagulation management for patients with atrial fibrillation: a pilot study	6
Will artificial intelligence chatbots replace clinical pharmacologists? An exploratory study in clinical practice	6
The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose–corrected trough concentration in the early period after liver transplantation	6
Clinical relevance of potentially inappropriate medications and potential prescribing omissions according to explicit criteria—a validation study	6
Effects of ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of abemaciclib	6
Serum 4β-hydroxycholesterol increases during fluconazole treatment	6
Effect of metformin as an adjuvant therapy to letrozole on estradiol and other biomarkers involved in the pathogenesis of breast cancer in overweight and obese postmenopausal women: a pilot study	6
Antiplatelet therapy for secondary prevention of lacunar stroke: a systematic review and network meta-analysis	6
Safety and efficacy of new oral anticoagulants compared to those of warfarin in AF patients with cancer: a meta-analysis of randomized clinical trials and observational studies	6
A patient-centred web-based adverse drug reaction reporting system identifies not yet labelled potential safety issues	6
Physiologically based pharmacokinetic model predictions of natural product-drug interactions between goldenseal, berberine, imatinib and bosutinib	6
The role of anti-diabetic drugs in NAFLD. Have we found the Holy Grail? A narrative review	6
Dapagliflozin reduces risk of heart failure rehospitalization in diabetic acute myocardial infarction patients: a propensity score-matched analysis	6
Application of physiologically based pharmacokinetic modeling to predict the pharmacokinetics of telavancin in obesity with renal impairment	6
Safety evaluation of oral calcitonin-gene–related peptide receptor antagonists in patients with acute migraine: a systematic review and meta-analysis	6
Patient involvement in pharmacovigilance: determinants and evolution of reporting from 2011 to 2020 in France	6
Once-daily 1 g ceftriaxone optimizes exposure in patients with septic shock and hypoalbuminemia receiving continuous veno-venous hemodiafiltration	6
Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype	6
Effectiveness of hypoxia-induced factor prolyl hydroxylase inhibitor for managing anemia in chronic kidney disease: a systematic review and meta-analysis	6
Impacts of cachexia progression in addition to serum IgG and blood lymphocytes on serum nivolumab in advanced cancer patients	6
The scientific basis of rational prescribing. A guide to precision clinical pharmacology based on the WHO 6-step method	6
Application of machine learning to predict tacrolimus exposure in liver and kidney transplant patients given the MeltDose formulation	6
Exploring heterogeneities of cardiovascular efficacy and effectiveness of SGLT2 inhibitors in patients with type 2 diabetes: an umbrella review of evidence from randomized clinical trials versus real-	6
CYP450 polymorphisms and clinical pharmacogenetics of ibuprofen after lower third molar extraction	6
The potential of training specialist oncology nurses in real-life reporting of adverse drug reactions	5

Evaluation of serum levels of asprosin and other metabolic profiles in patients with idiopathic tonic–clonic generalized epilepsy on treatment with valproic acid	5
Role of ADME gene polymorphisms on imatinib disposition: results from a population pharmacokinetic study in chronic myeloid leukaemia	5
Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients	5
Attitudes and beliefs of older adults and caregivers towards deprescribing in French-speaking countries: a multicenter cross-sectional study	5
Repositioning HIV protease inhibitors and nucleos(t)ide RNA polymerase inhibitors for the treatment of SARS-CoV-2 infection and COVID-19	5
Lack of association between proton pump inhibitor use and brain aging: a cross-sectional study	5
The motivations, barriers, and sociodemographic characteristics of healthy Chinese volunteers in phase I research	5
A standard dose of linezolid puts patients with hepatic impairment at risk of overexposure	5
The pharmacokinetic interaction between nasally administered naloxone and the opioid remifentanil in human volunteers	5
Anticholinergic load and delirium in end-of-life patients	5
Proton pump inhibitors and osteoporosis risk: exploring the role of TRPM7 channel	5
Effects of sacubitril/valsartan on exercise capacity: a prognostic improvement that starts during uptitration	5
The impact of omega-3 polyunsaturated fatty acids on primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials	5
Impact of tofogliflozin on hepatic outcomes: a systematic review	5
Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability	5
Teicoplanin physiologically based pharmacokinetic modeling offers a quantitative assessment of a theoretical influence of serum albumin and renal function on its disposition	5
Predicting the presence and mechanism of busulfan drug-drug interactions in hematopoietic stem cell transplantation using pharmacokinetic interaction network–based molecular structure similarity and n	5
The association between the availability of over the counter codeine and the prevalence of non-medical use	5
Drug-drug interactions and inappropriate medicines impact on glycemic control and kidney function in older adults with diabetes-attending specialty care institution	5
Self-reported medication adherence and pharmacy refill adherence among persons with ischemic stroke: a cross-sectional study	5
Sex differences in serious adverse drug reactions in patients receiving immunotherapy, targeted therapy, or chemotherapy: a disproportionality analysis of the VigiBase®	5
Medication incident recovery and prevention utilising an Australian community pharmacy incident reporting system: the QUMwatch study	5
Medication adherence among persons with coronary heart disease and associations with blood pressure and low-density-lipoprotein-cholesterol	5
Psychotropic drug use among older people with major neurocognitive disorder: a cross-sectional study based on Swedish national registries	5
Pharmacokinetics of benapenem for injection in subjects with mild to moderate renal impairment	5
Does aspirin reduce the incidence, recurrence, and mortality of hepatocellular carcinoma? A GRADE-assessed systematic review and dose–response meta-analysis	5
Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study	5
Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass in adult patients undergoing cardiac surgery	5
Impact of suspected adverse drug reactions on mortality and length of hospital stay in the hospitalised patients: a meta-analysis	5
Hospitalisations related to benzodiazepine, Z-drug, and opioid treatment in Italy: a claim on the risks associated with inappropriate use	5
A review of an investigational drug retatrutide, a novel triple agonist agent for the treatment of obesity	5
Metabolic diversity as a reason for unsuccessful detoxification from benzodiazepines: the rationale for serum BZD concentration monitoring	5
Population pharmacokinetics of cefotaxime in intensive care patients	5
Evaluation of the safety and tolerability of spironolactone in patients with heart failure and chronic kidney disease	5
In silico comparison of pharmacokinetic properties of three extended half-life factor IX concentrates	5
Trends and variation in benzodiazepine use in nursing homes in the USA	5
Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study	5
Perception of clinical research among patients and healthy volunteers of clinical trials	5
Evidence-based medication adherence among seniors in the first year after heart failure hospitalisation and subsequent long-term outcomes: a restricted cubic spline analysis of adherence-outcome relat	5
Clinical comparative study assessing the effect of ivabradine on neopterin and NT-Pro BNP against standard treatment in chronic heart failure patients	5
Fatal adverse events of rivaroxaban combined with aspirin: an analysis using data from VigiBase	5
Post-market utilization patterns of Alzheimer’s disease treatments in South Korea: comparison with countries with universal health coverage	5
Immune-mediated necrotizing myopathy with pembrolizumab: a specific neuromuscular entity	5
Does ramadan fasting affect the therapeutic and clinical outcomes of warfarin? a systematic review and meta-analysis	5
Coenzyme Q10 as a potential add-on treatment for patients suffering from painful diabetic neuropathy: results of a placebo-controlled randomized trial	5
The impact of health literacy on beliefs about medication in a Dutch medication-using population	5
Dipeptidyl-peptidase-4 inhibitors have anti-inflammatory effects in patients with type 2 diabetes	5