OOIR: Observatory of International Research

Papers

(The TQCC of Pflugers Archiv-European Journal of Physiology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Transcriptional factors in calcium mishandling and atrial fibrillation development	54
Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke	50
Combining different ion-selective channelrhodopsins to control water flux by light	42
Development of autonomic heart rate modulations during childhood and adolescence	39
Zebrafish cardiac repolarization does not functionally depend on the expression of the hERG1b-like transcript	39
Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation	35
Decoding influences of indoor temperature and light on neural activity: entropy analysis of electroencephalographic signals	32
Evaluation of the relationship between intercostal muscle oxygenation measured by near-infrared spectroscopy and exercise capacity in group E COPD patients	32
Causality and scientific explanation of artificial intelligence systems in biomedicine	31
Impact of aldosterone deficiency on the development of diuretic resistance in mice	28
Resting membrane state as an interplay of electrogenic transporters with various pumps	28
Metabolic instability vs fibre recruitment contribution to the $${\dot{V}O_2}$$ slow component in different exercise intensity domains	27
Piezo1, the new actor in cell volume regulation	27
Linking mitochondrial dynamics and fertility: promoting fertility by phoenixin through modulation of ovarian expression of GnRH receptor and mitochondrial dynamics proteins DRP-1 and Mfn-2	26
One hundred years from Otto Loewi experiment, a dream that revolutionized our view of neurotransmission	26
Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells	25
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity	24
Commentary on: Bassetti, D., Luhmann, H.J., Kirischuk, S. Presynaptic GABAB receptor-mediated network excitation in the medial prefrontal cortex of Tsc2 + / − mice	24
Lipid metabolic reprogramming by hypoxia-inducible factor-1 in the hypoxic tumour microenvironment	22
FGF-23 protects cell function and viability in murine pancreatic islets challenged by glucolipotoxicity	21
AFM-based nanoindentation indicates an impaired cortical stiffness in the AAV-PCSK9DY atherosclerosis mouse model	21
Is XPR1 mediating phosphate efflux?	20
Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling	20
Blood transcriptomics mirror regulatory mechanisms during hibernation—a comparative analysis of the Djungarian hamster with other mammalian species	20
Measured GFR in murine animal models: review on methods, techniques, and procedures	20

XPR1: a regulator of cellular phosphate homeostasis rather than a Pi exporter	19
Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection	19
Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys	18
A role for plasma membrane Ca2+ ATPases in regulation of cellular Ca2+ homeostasis by sphingosine kinase-1	18
Nobel Prize for physiology or medicine in 2024 for the discovery of microRNAs: small RNAs with fundamental roles in development and disease	17
Regulation of endothelial function by cigarette smoke and next-generation tobacco and nicotine products	16
Comprehensive overview of artificial intelligence in surgery: a systematic review and perspectives	16
News in caecal signalling: the role of propionate in microbial-epithelial crosstalk	16
Neuroprotective actions of norepinephrine in neurological diseases	16
Identification of Dp140 and α1-syntrophin as novel molecular interactors of the neuronal CaV2.1 channel	16
Sphingosine kinase 1 inhibition aggravates vascular smooth muscle cell calcification	16
Effects of butyrate− on ruminal Ca2+ transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels	16
Novel functions of the anion exchanger AE4 (SLC4A9)	15
The extracellular matrix protein fibronectin promotes metanephric kidney development	14
Correction to: Nobel somatosensations and pain	14
Mechanisms underlying spontaneous phasic contractions and sympathetic control of smooth muscle in the rat caudal epididymis	14
Correction to: Indoxyl sulfate enhances endothelin-1-induced contraction via impairment of NO/cGMP signaling in rat aorta	14
Controlled dietary phosphate loading in healthy young men elevates plasma phosphate and FGF23 levels	13
Evaluation of skeletal muscle function in male rats with doxorubicin-induced myopathy following various exercise techniques: the significant role of glucose transporter 4	13
Immune mediators in heart–lung communication	13
Functional characterization of acid-sensing ion channels in the cerebellum-originating medulloblastoma cell line DAOY and in cerebellar granule neurons	13
Obituary for Prof. Stephen (Ben) Walsh, Professor of Nephrology at University College London	12
BK channels promote action potential repolarization in skeletal muscle but contribute little to myotonia	12
Voltage-dependent CaV3.2 and CaV2.2 channels in nociceptive pathways	12
What can we learn about acid-base transporters in cancer from studying somatic mutations in their genes?	12
Interphotoreceptor coupling: an evolutionary perspective	12
Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?	11
AMPK facilitates the hypoxic ventilatory response through non-adrenergic mechanisms at the brainstem	11
Obituary Peter H. Deetjen (1932–2024): Editor-in-Chief of Pflügers Archiv from 1970 to 1998	11
Colonic expression of calcium transporter TRPV6 is regulated by dietary sodium butyrate	11
Basal release of 6-cyanodopamine from rat isolated vas deferens and its role on the tissue contractility	11
Emerging connections between Piezo1 and BK channels in vascular smooth muscle cells	11
Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats	11
Effects of tDCS on glutamatergic pathways in epilepsy: neuroprotective and therapeutic potential	11
Cell surface ATP synthase-released H+ and ATP play key roles in cocoa butter intake-mediated regulation of gut immunity through releases of cytokines in rat	11
Alteration of Piezo1 signaling in type 2 diabetic mice: focus on endothelium and BKCa channel	11
The role of Na+-coupled bicarbonate transporters (NCBT) in health and disease	11
Commentary on “Failer et al. (2022) Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation” J Clin Invest 2022 (https://doi.org/10.1172/JCI	10
The lateral habenula regulates stress-related respiratory responses via the monoaminergic system	10
Effects of aconitine on the respiratory activity of brainstem-spinal cord preparations isolated from newborn rats	10
Strength and muscle mass development after a resistance-training period at terrestrial and normobaric intermittent hypoxia	10
Peripheral arterial tone during active standing	10
GPD1L-A306del modifies sodium current in a family carrying the dysfunctional SCN5A-G1661R mutation associated with Brugada syndrome	10
A role for TRPC5 in cold sensing, finally	10
Renal water transport in health and disease	9
Strengthening the basics: acids and bases influence vascular structure and function, tissue perfusion, blood pressure, and human cardiovascular disease	9
Inconclusive evidence that breathing shapes pupil dynamics in humans: a systematic review	9
Recent advances in acid sensing by G protein coupled receptors	9
Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations	9
Correction to: Differential frequency-dependent reflex summation of the aortic baroreceptor afferent input	9

Optimization of an autaptic culture system for studying cholinergic synapses in sympathetic ganglia	9
Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain	9
The role of non-coding RNAs in neuropathic pain	9
Correction to: Effect of salivary gland removal on taste preference in mice	9
Intermittent hypoxia training effectively protects against cognitive decline caused by acute hypoxia exposure	9
Potential regulatory role of PGC-1α within the skeletal muscle during metabolic adaptations in response to high-fat diet feeding in animal models	9
“The great mixing machine”: multisensory integration and brain-breath coupling in the cerebral cortex	8
The context-dependent role of the Na+/Ca2+-exchanger (NCX) in pancreatic stellate cell migration	8
14–3-3 protein regulation of excitation–contraction coupling	8
Two firing modes and well-resolved Na+, K+, and Ca2+ currents at the cell-microelectrode junction of spontaneously active rat chromaffin cell on MEAs	8
Skeletal muscle proteins involved in fatty acid transport influence fatty acid oxidation rates observed during exercise	8
Insights into permeability control of the fenestrated endothelium of the jejunal microvasculature	8
Oligodendrocyte precursor cells: the multitaskers in the brain	8
CFTR—a (novel) target in ARDS	8
Biophysical mechanisms of myocardium sodium channelopathies	8
Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging‐induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats	8
Unlocking the potential: unveiling tyrphostins with Michael-reactive cyanoacrylate motif as promising inhibitors of human 5-lipoxygenase	7
Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis	7
Responsiveness of afferent renal nerve units in renovascular hypertension in rats	7
Intracellular pH regulates the strength of the intrinsic inward rectification of Kir4.1/Kir5.1 channels	7
Hypoxia-inducible factor-driven glycolytic adaptations in host-microbe interactions	7
Correction to: Dynamic expression of homeostatic ion channels in differentiated cortical astrocytes in vitro	7
Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice	7
High-fat diet-induced mitochondrial dysfunction is associated with loss of protection from ischemic preconditioning in renal ischemia reperfusion	7
Proteolytic ENaC activation in health and disease—a complicated puzzle	7
Exposure to normobaric hypoxia shapes the acute inflammatory response in human whole blood cells in vivo	7
Determinants of hypokalemia following hypertonic sodium bicarbonate infusion	7
PKC regulates αKlotho gene expression in MDCK and NRK-52E cells	7
Uncovering the neural control of laryngeal activity and subglottic pressure in anaesthetized rats: insights from mesencephalic regions	7
Phosphate intake, hyperphosphatemia, and kidney function	7
Indoxyl sulfate enhances endothelin-1-induced contraction via impairment of NO/cGMP signaling in rat aorta	7
Special issue on recent progress with hPSC-derived cardiovascular cells for organoids, engineered myocardium, drug discovery, disease models, and therapy	7
Correction to: Persistent sodium currents in neurons: potential mechanisms and pharmacological blockers	7
Interleukin 17A infusion has no acute or long-term hypertensive action in conscious unrestrained male mice	7
Extended spectrum of Cav1.3 channelopathies	6
Intra- and inter-session reliability of electrical detection and pain thresholds of cutaneous and muscle primary afferents in the lower back of healthy individuals	6
The ex vivo perfused mouse adrenal gland—a new model to study aldosterone secretion	6
Dopamine receptor D4 (DRD4) negatively regulates UCP1- and ATP-dependent thermogenesis in 3T3-L1 adipocytes and C2C12 muscle cells	6
Clenbuterol-sensitive delayed outward potassium currents in a cell model of spinal and bulbar muscular atrophy	6
Tuft cell integration of luminal states and interaction modules in tissues	6
Presynaptic GABAB receptor–mediated network excitation in the medial prefrontal cortex of Tsc2+/- mice	6
The role of GABA in modulation of taste signaling within the taste bud	6
Acid-sensing ion channels and downstream signalling in cancer cells: is there a mechanistic link?	6
The crucial decade that ion channels were proven to exist	6
Identification of a novel redox switch between metabolism and cardiac function using HyPer power	6
Lessons from a model: early glucagon dysfunction in type 2 diabetes	6
Cargo-specific effects of hypoxia on clathrin-mediated trafficking	6
Role of natriuretic peptides in the cardiovascular-adipose communication: a tale of two organs	6
Diet-induced impairment of skeletal muscle and adipose tissue metabolic homeostasis and its prevention by probiotic administration	6
Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and KCa3.1 ion channels, but involves phosphoinositide 3-kinase	6
Correction to: Two adjacent phosphorylation sites in the C-terminus of the channel’s α-subunit have opposing effects on epithelial sodium channel (ENaC) activity	6
Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes	6
Structure and dynamics of photoreceptor sensory cilia	6
Cobalt chloride postconditioning as myoprotective therapy in cardiac ischemia–reperfusion	6
E-cigarette effects on vascular function in animals and humans	5
Role of glucocorticoid receptor mutations in hypertension and adrenal gland hyperplasia	5
Correction to: SGLT2 and cancer	5
hPSC gene editing for cardiac disease therapy	5
Microbiota, mitochondria, and epigenetics in health and disease: converging pathways to solve the puzzle	5
25-Hydroxycholesterol modulates synaptic vesicle endocytosis at the mouse neuromuscular junction	5
No single place for space: neuronal representation of location beyond the hippocampus	5
Connexin mRNA distribution in adult mouse kidneys	5
Recent advances and current limitations of available technology to optically manipulate and observe cardiac electrophysiology	5
Does the composition of urinary extracellular vesicles reflect the abundance of renal Na+/phosphate transporters?	5
Tissue chaperoning—the expanded functions of fetuin-A beyond inhibition of systemic calcification	5
Angiotensin receptors and α1B-adrenergic receptors regulate native IK(ACh) and phosphorylation-deficient GIRK4 (S418A) channels through different PKC isoforms	5
New insights about non-neurogenic excitability revealed by MEA recordings from rat adrenal chromaffin cells	5
MiR-10b-3p alleviates cerebral ischemia/reperfusion injury by targeting Krüppel-like factor 5 (KLF5)	5
Galectin-3 protects distal convoluted tubules in rhabdomyolysis-induced kidney injury	5
Characterization and functional role of rapid- and slow-activating delayed rectifier K+ currents in atrioventricular node cells of guinea pigs	5
Excitation-secretion coupling in chromaffin cells of the adrenal gland: Where does calcium come from?	5
Intracellular cAMP signaling-induced Ca2+ influx mediated by calcium homeostasis modulator 1 (CALHM1) in human odontoblasts	5