Pflugers Archiv-European Journal of Physiology

Article	Citations
Perfluorocarbon-based oxygen carriers: from physics to physiology	115
Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research	52
Long non-coding RNAs: novel regulators of cellular physiology and function	44
Resting-state networks in the course of aging—differential insights from studies across the lifespan vs. amongst the old	42
Vascular and haemodynamic issues of brain ageing	36
Kidney metabolism and acid–base control: back to the basics	33
The role of cGMP-signalling and calcium-signalling in photoreceptor cell death: perspectives for therapy development	32
Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway	31
The regulation of FGF23 under physiological and pathophysiological conditions	30
Common and discrete mechanisms underlying chronic pain and itch: peripheral and central sensitization	29
Nobel Prize 2020 in Chemistry honors CRISPR: a tool for rewriting the code of life	29
Potassium homeostasis: sensors, mediators, and targets	29
The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium	28
Structure and dynamics of photoreceptor sensory cilia	27
Transmission at rod and cone ribbon synapses in the retina	27
Renal blood flow and oxygenation	27
Biochemistry and physiology of zebrafish photoreceptors	27
Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy	26
Cardiac small-conductance calcium-activated potassium channels in health and disease	25
A detailed characterization of the hyperpolarization-activated “funny” current (If) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity	24
Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology	22
Changes in sleep EEG with aging in humans and rodents	22
Atrial fibrillation rhythm is associated with marked changes in metabolic and myofibrillar protein expression in left atrial appendage	21
Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection	21
Interplay between bioenergetics and oxidative stress at normal brain aging. Aging as a result of increasing disbalance in the system oxidative stress–energy provision	21

Phosphate intake, hyperphosphatemia, and kidney function	21
CNG channel structure, function, and gating: a tale of conformational flexibility	21
Regulation of mitochondrial temperature in health and disease	19
Voltage-dependent CaV3.2 and CaV2.2 channels in nociceptive pathways	19
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice	19
Keeping the ageing brain wired: a role for purine signalling in regulating cellular metabolism in oligodendrocyte progenitors	19
The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation	19
Nobel somatosensations and pain	18
Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones	18
Breathing modulates gamma synchronization across species	17
Physiological relevance of proton-activated GPCRs	17
Is carbonyl/AGE/RAGE stress a hallmark of the brain aging?	17
Olfactory impairment in men and mice related to aging and amyloid-induced pathology	16
Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells	16
Tissue chaperoning—the expanded functions of fetuin-A beyond inhibition of systemic calcification	16
Ca2+ mishandling and mitochondrial dysfunction: a converging road to prediabetic and diabetic cardiomyopathy	16
Role of vitamins in the metabolic syndrome and cardiovascular disease	16
TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei	15
Regulation of retinal membrane guanylyl cyclase (RetGC) by negative calcium feedback and RD3 protein	15
Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells	15
Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine	15
Oligodendrocyte precursor cells: the multitaskers in the brain	14
Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and KCa3.1 ion channels, but involves phosphoinositide 3-kinase	14
Upregulation of transient receptor potential melastatin 4 (TRPM4) in ventricular fibroblasts from heart failure patients	14
The role of calcium homeostasis remodeling in inherited cardiac arrhythmia syndromes	14
Light responses of mammalian cones	13
Sex difference in kidney electrolyte transport III: Impact of low K intake on thiazide-sensitive cation excretion in male and female mice	13
Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC	13
Cav1.4 dysfunction and congenital stationary night blindness type 2	13
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking	13
Mechanisms underlying pathological Ca2+ handling in diseases of the heart	13
Functional subgroups of rat and human sensory neurons: a systematic review of electrophysiological properties	13
Lipid metabolic reprogramming by hypoxia-inducible factor-1 in the hypoxic tumour microenvironment	13
Respiratory influence on brain dynamics: the preponderant role of the nasal pathway and deep slow regime	12
E-cigarette effects on vascular function in animals and humans	12
MiRNA-190 exerts neuroprotective effects against ischemic stroke through Rho/Rho-kinase pathway	12
Presynaptic GABAB receptor–mediated network excitation in the medial prefrontal cortex of Tsc2+/- mice	12
UMOD and the architecture of kidney disease	12
Decreased KLHL3 expression is involved in the activation of WNK-OSR1/SPAK-NCC cascade in type 1 diabetic mice	11
Fount, fate, features, and function of renal erythropoietin-producing cells	11
Excitation-contraction coupling and calcium release in atrial muscle	11
Peripheral receptors and neuromediators involved in the antihyperalgesic effects of acupuncture: a state-of-the-art review	11
Mineralocorticoid receptor-antagonism prevents COVID-19-dependent glycocalyx damage	11
Soluble αKlotho downregulates Orai1-mediated store-operated Ca2+ entry via PI3K-dependent signaling	11
Single nephron glomerular filtration rate measured by linescan multiphoton microscopy compared to conventional micropuncture	10
The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule	10
Regulation of endothelial function by cigarette smoke and next-generation tobacco and nicotine products	10
( −)-Epicatechin and cardiometabolic risk factors: a focus on potential mechanisms of action	10
14–3-3 protein regulation of excitation–contraction coupling	10
Increasing whole-body energetic stress does not augment fasting-induced changes in human skeletal muscle	10

The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise	10
Controlling neuronal assemblies: a fundamental function of respiration-related brain oscillations in neuronal networks	10
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity	10
Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis	10
Functional compartmentalization of photoreceptor neurons	10
Cardiac adaptation and cardioprotection against arrhythmias and ischemia-reperfusion injury in mammalian hibernators	10
Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation	10
Ventrolateral periaqueductal gray matter integrative system of defense and antinociception	10
Flexible and multifaceted: the plasticity of renin-expressing cells	10
Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels	9
Respiratory entrainment of units in the mouse parietal cortex depends on vigilance state	9
Comparative study of the effects of cigarette smoke versus next-generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes	9
Metabolic mechanisms of acute proximal tubular injury	9
Myostatin regulates the production of fibroblast growth factor 23 (FGF23) in UMR106 osteoblast–like cells	9
Structural aspects of rod opsin and their implication in genetic diseases	9
Cereblon: promise and challenges for combating human diseases	9
Importance of evaluating protein glycosylation in pluripotent stem cell-derived cardiomyocytes for research and clinical applications	9
Vascularisation of pluripotent stem cell–derived myocardium: biomechanical insights for physiological relevance in cardiac tissue engineering	9
SOCE in the cardiomyocyte: the secret is in the chambers	9
Renal water transport in health and disease	9
The importance of kidney calcium handling in the homeostasis of extracellular fluid calcium	9
Eccentric muscle contractions: from single muscle fibre to whole muscle mechanics	8
Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system	8
Comparative lipid profiling of murine and human atherosclerotic plaques using high-resolution MALDI MSI	8
(H)IF applicable: promotion of neurogenesis by induced HIF-2 signalling after ischaemia	8
Lithium enhances exercise-induced glycogen breakdown and insulin-induced AKT activation to facilitate glucose uptake in rodent skeletal muscle	8
Electrophysiological characterization of ectopic spontaneous discharge in axotomized and intact fibers upon nerve transection: a role in spontaneous pain?	8
Electroacupuncture decreases inflammatory pain through a pro-resolving mechanism involving the peripheral annexin A1-formyl peptide receptor 2/ALX-opioid receptor pathway	8
Beyond Ca2+ signalling: the role of TRPV3 in the transport of NH4+	8
β-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia	8
Slow recovery from the inactivation of voltage-gated sodium channel Nav1.3 in mouse taste receptor cells	8
Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling	8
Protection of kidney function and tissue integrity by pharmacologic use of natriuretic peptides and neprilysin inhibitors	8
Regulation of CaV3.2 channels by the receptor for activated C kinase 1 (Rack-1)	8
Mechanisms of ion transport regulation by HNF1β in the kidney: beyond transcriptional regulation of channels and transporters	7
Carbonic anhydrase IX and hypoxia-inducible factor 1 attenuate cardiac dysfunction after myocardial infarction	7
TRIC-A regulates intracellular Ca2+ homeostasis in cardiomyocytes	7
AFM-based nanoindentation indicates an impaired cortical stiffness in the AAV-PCSK9DY atherosclerosis mouse model	7
Functional expression of mitochondrial KCa3.1 channels in non-small cell lung cancer cells	7
Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain	7
The anion exchanger PAT-1 (Slc26a6) does not participate in oxalate or chloride transport by mouse large intestine	7
Interphotoreceptor coupling: an evolutionary perspective	7
Tuft cell integration of luminal states and interaction modules in tissues	7
Cell surface markers for immunophenotyping human pluripotent stem cell-derived cardiomyocytes	7
Metabolic instability vs fibre recruitment contribution to the $${\dot{V}O_2}$$ slow component in different exercise intensity domains	7
Influence of layer separation on the determination of stomach smooth muscle properties	7
The bile acid-sensitive ion channel (BASIC) mediates bile acid-dependent currents in bile duct epithelial cells	7
The role of adrenergic and muscarinic receptors in stress-induced cardiac injury	7
The regulation of the small-conductance calcium-activated potassium current and the mechanisms of sex dimorphism in J wave syndrome	7
One hundred years from Otto Loewi experiment, a dream that revolutionized our view of neurotransmission	7
Promotion of aging heart function and its redox balance following hind-limb blood flow restriction plus endurance exercise training in rats: klotho and PGC1-α as involving candidate molecules	7
The role of acrolein for E-cigarette vapour condensate mediated activation of NADPH oxidase in cultured endothelial cells and macrophages	6
Alterations of housekeeping proteins in human aged and diseased hearts	6
MicroRNA-1246 regulates proliferation, invasion, and differentiation in human vascular smooth muscle cells by targeting cystic fibrosis transmembrane conductance regulator (CFTR)	6
Potentiation of force by extracellular potassium and posttetanic potentiation are additive in mouse fast-twitch muscle in vitro	6
Pathological mechanisms of cigarette smoking, dietary, and sedentary lifestyle risks in vascular dysfunction: mitochondria as a common target of risk factors	6
Connexin mRNA distribution in adult mouse kidneys	6
Pain quality patterns in delayed onset muscle soreness of the lower back suggest sensitization of fascia rather than muscle afferents: a secondary analysis study	6
A5 noradrenergic neurons and breathing control in neonate rats	6
Piezo1, the new actor in cell volume regulation	6
Left ventricular depression and pulmonary edema in rats after short-term normobaric hypoxia: effects of adrenergic blockade and reduced fluid load	6
Tobacco smoking and vascular biology and function: evidence from human studies	6
L-cysteine modulates visceral nociception mediated by the CaV2.3 R-type calcium channels	6
MiR-10b-3p alleviates cerebral ischemia/reperfusion injury by targeting Krüppel-like factor 5 (KLF5)	6
Endurance-dependent urinary extracellular vesicle signature: shape, metabolic miRNAs, and purine content distinguish triathletes from inactive people	6
Supramolecular organization of rhodopsin in rod photoreceptor cell membranes	6
Proteolytic ENaC activation in health and disease—a complicated puzzle	6
Dynamics of neocortical networks: connectivity beyond the canonical microcircuit	6
Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES	6
Ion channel long non-coding RNAs in neuropathic pain	6
Apolipoprotein L1 (APOL1) cation current in HEK-293 cells and in human podocytes	6
Exercise and vascular function in sedentary lifestyles in humans	6
The medial prefrontal cortex and the cardiac baroreflex activity: physiological and pathological implications	6
Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys	6
Loss of the large conductance calcium-activated potassium channel causes an increase in mitochondrial reactive oxygen species in glioblastoma cells	5
Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations	5
Simulating cardiac Ca2+ release units: effects of RyR cluster size and Ca2+ buffers on diastolic Ca2+ leak	5
Impact of the glutamatergic neurotransmission within the A5 region on the cardiorespiratory response evoked from the midbrain dlPAG	5
Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart	5
Linking mitochondrial dynamics and fertility: promoting fertility by phoenixin through modulation of ovarian expression of GnRH receptor and mitochondrial dynamics proteins DRP-1 and Mfn-2	5

Two firing modes and well-resolved Na+, K+, and Ca2+ currents at the cell-microelectrode junction of spontaneously active rat chromaffin cell on MEAs	5
Oxygen-dependent regulation of ion channels: acute responses, post-translational modification, and response to chronic hypoxia	5
Ginkgolide B caused the activation of the Akt/eNOS pathway through the antioxidant effect of SOD1 in the diabetic aorta	5
The role of voltage-gated ion channels in visual function and disease in mammalian photoreceptors	5
Mechanisms underlying spontaneous phasic contractions and sympathetic control of smooth muscle in the rat caudal epididymis	5
Electrophysiological characterization of a CaV3.1 calcium channel mutation linked to trigeminal neuralgia	5
Towards bridging the translational gap by improved modeling of human nociception in health and disease	5
Is there a molecular basis for solvent drag in the renal proximal tubule?	5
Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?	5
Human pluripotent stem cell–based cardiovascular disease modeling and drug discovery	5
Role of natriuretic peptides in the cardiovascular-adipose communication: a tale of two organs	5
Where vision begins	5
Human platelet mitochondria improve the mitochondrial and cardiac function of donor heart	5
Discordant Ca2+ release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation	4
Sexually dimorphic effects of prenatal diazepam exposure on respiratory control and the monoaminergic system of neonate and young rats	4
The context-dependent role of the Na+/Ca2+-exchanger (NCX) in pancreatic stellate cell migration	4
Investigation into the difference in mitochondrial-cytosolic calcium coupling between adult cardiomyocyte and hiPSC-CM using a novel multifunctional genetic probe	4
Role of glucocorticoid receptor mutations in hypertension and adrenal gland hyperplasia	4
SNAT2 is responsible for hyperosmotic induced sarcosine and glycine uptake in human prostate PC-3 cells	4
Dopamine receptor D4 (DRD4) negatively regulates UCP1- and ATP-dependent thermogenesis in 3T3-L1 adipocytes and C2C12 muscle cells	4
Myocardial angiogenesis induced by concurrent vitamin D supplementation and aerobic-resistance training is mediated by inhibiting miRNA-15a, and miRNA-146a and upregulating VEGF/PI3K/eNOS signaling pa	4
Water intake releases serotonin from enterochromaffin cells in rat jejunal villi	4
Dietary acid load in health and disease	4
Enhancement of airway ciliary beating mediated via voltage-gated Ca2+ channels/α7-nicotinic receptors in mice	4
Endothelin receptors in renal interstitial cells do not contribute to the development of fibrosis during experimental kidney disease	4
Clues and new evidences in arterial hypertension: unmasking the role of the chloride anion	4
Relevance of mitochondrial dysfunction in heart disease associated with insulin resistance conditions	4
The renin angiotensin aldosterone system	4
AMPK facilitates the hypoxic ventilatory response through non-adrenergic mechanisms at the brainstem	4
AMPK in the gut-liver-brain axis and its influence on OP rats in an HSHF intake and WTD rat model	4
Indoxyl sulfate enhances endothelin-1-induced contraction via impairment of NO/cGMP signaling in rat aorta	4
Clenbuterol-sensitive delayed outward potassium currents in a cell model of spinal and bulbar muscular atrophy	4
Understanding normal brain aging	4
Acid-sensing ion channels and downstream signalling in cancer cells: is there a mechanistic link?	4
Editing of the myosin phosphatase regulatory subunit suppresses angiotensin II induced hypertension via sensitization to nitric oxide mediated vasodilation	4
Skeletal muscle proteins involved in fatty acid transport influence fatty acid oxidation rates observed during exercise	4
Inconclusive evidence that breathing shapes pupil dynamics in humans: a systematic review	4
A novel mutation in KCNH2 yields loss-of-function of hERG potassium channel in long QT syndrome 2	4
Modulation of inspiratory burst duration and frequency by bombesin in vitro	4
The updated view on induced pluripotent stem cells for cardiovascular precision medicine	4
Expression of phosphate and calcium transporters and their regulators in parotid glands of mice	4
New functions and roles of the Na+-H+-exchanger NHE3	4
Responsiveness of afferent renal nerve units in renovascular hypertension in rats	4
The role of acid-sensing ion channels in monosodium urate-induced gouty pain in mice	3
Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke	3
Further evidence against the role renal medullary perfusion in short-term control of arterial pressure in normotensive and mildly or overtly hypertensive rats	3
Strengthening the basics: acids and bases influence vascular structure and function, tissue perfusion, blood pressure, and human cardiovascular disease	3
Peripheral arterial tone during active standing	3
Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract	3
Role of PTHrP in attenuating transient pressure rises and associated afferent nerve activity of the rat bladder	3
Recent advances and current limitations of available technology to optically manipulate and observe cardiac electrophysiology	3
Function follows form: how the structure of neurons determines cortical network activity	3
Exercise regulates shelterin genes and microRNAs implicated in ageing in Thoroughbred horses	3
Aminophylline at clinically relevant concentrations affects inward rectifier potassium current in a dual way	3
Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular innervation	3
Alcohol and the vasculature: a love-hate relationship?	3
High-fat diet-induced mitochondrial dysfunction is associated with loss of protection from ischemic preconditioning in renal ischemia reperfusion	3
Effects of reversible SERCA inhibition on catecholamine exocytosis and intracellular [Ca2+] signaling in chromaffin cells from normotensive Wistar Kyoto rats and spontaneously hypertensive rats	3
The role of HCO3– in propionate-induced anion secretion across rat caecal epithelium	3
Inhibition of late sodium current via PI3K/Akt signaling prevents cellular remodeling in tachypacing-induced HL-1 atrial myocytes	3
Differential regulation of medium spiny and cholinergic neurons in the nucleus accumbens core by the insular and medial prefrontal cortices in the rat	3
Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle	3
Colonic expression of calcium transporter TRPV6 is regulated by dietary sodium butyrate	3
Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk	3
Cuprizone feeding induces swollen astrocyte endfeet	3
Ventromedial prefrontal cortex CRF1 receptors modulate the tachycardic activity of baroreflex	3
Determinants of hypokalemia following hypertonic sodium bicarbonate infusion	3
Hypotension in hereditary cardiomyopathy	3
Cigarette smoke extract induces foam cell formation by impairing machinery involved in lipid droplet degradation	3
Development of the hypersecretory phenotype in the population of adrenal chromaffin cells from prehypertensive SHRs	3
Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat	3
Multimodal cortical neuronal cell type classification	3
Two adjacent phosphorylation sites in the C-terminus of the channel’s α-subunit have opposing effects on epithelial sodium channel (ENaC) activity	3
A novel beneficial role of humanin on intestinal apoptosis and dysmotility in a rat model of ischemia reperfusion injury	3
Body and mind: how somatic feedback signals shape brain activity and cognition	3
Could respiration-driven blood oxygen changes modulate neural activity?	3
A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects	2
Higher expression of KCNK10 (TREK-2) K+ channels and their functional upregulation by lipopolysaccharide treatment in mouse peritoneal B1a cells	2
Optogenetically mediated large volume suppression and synchronized excitation of human ventricular cardiomyocytes	2
Giant Y79 retinoblastoma cells contain functionally active T-type calcium channels	2
MALDI MSI for a fresh view on atherosclerotic plaque lipids	2
Temporal and spatial summation of laser heat stimuli in cultured nociceptive neurons of the rat	2
Neurogenic substance P—influences on action potential production in afferent neurons of the kidney?	2
Interleukin 17A infusion has no acute or long-term hypertensive action in conscious unrestrained male mice	2
Combining different ion-selective channelrhodopsins to control water flux by light	2
Transcriptional factors in calcium mishandling and atrial fibrillation development	2
Inhibition of Ca2+-dependent protein kinase C rescues high calcium–induced pro-arrhythmogenic cardiac alternans in rabbit hearts	2
Effects of butyrate− on ruminal Ca2+ transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels	2
Advances in understanding the state of titin truncation variants in dilated cardiomyopathy	2
The impact of progredient vessel and tissue stiffening for the development of metabolic syndrome	2
Metabolic acidosis in chronic kidney disease: mere consequence or also culprit?	2
Resting membrane state as an interplay of electrogenic transporters with various pumps	2
Forty years of the adrenal chromaffin cell through ISCCB meetings around the world	2
Secretin: a hormone for HCO3− homeostasis	2
HIF-2: an important player in neuronal response to ischemia	2