Pflugers Archiv-European Journal of Physiology

Article	Citations
Glucose transporters in brain in health and disease	239
Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease	216
The molecular mechanisms of copper metabolism and its roles in human diseases	163
Glucose transporters in the small intestine in health and disease	126
Structure, function and regulation of mammalian glucose transporters of the SLC2 family	100
Perfluorocarbon-based oxygen carriers: from physics to physiology	97
Transporters of glucose and other carbohydrates in bacteria	75
Taste transduction and channel synapses in taste buds	67
GDF15, an update of the physiological and pathological roles it plays: a review	64
Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain	64
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction	61
Glucose transporters in pancreatic islets	58
Cardiac and neuronal HCN channelopathies	55
Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application	52
Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research	42
Neuronal Cav3 channelopathies: recent progress and perspectives	38
De novo CACAN1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism	35
Resting-state networks in the course of aging—differential insights from studies across the lifespan vs. amongst the old	34
Glucose transporters in cardiovascular system in health and disease	33
Long non-coding RNAs: novel regulators of cellular physiology and function	30
SGLT2 and cancer	30
Vascular and haemodynamic issues of brain ageing	29
Skeletal muscle ClC-1 chloride channels in health and diseases	29
The role of cGMP-signalling and calcium-signalling in photoreceptor cell death: perspectives for therapy development	29
Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway	27

Nobel Prize 2020 in Chemistry honors CRISPR: a tool for rewriting the code of life	27
Metabolic implications of circadian disruption	26
It takes more than two to tango: mechanosignaling of the endothelial surface	26
Neuronal α2δ proteins and brain disorders	25
Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels	24
The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium	24
Transmission at rod and cone ribbon synapses in the retina	24
Common and discrete mechanisms underlying chronic pain and itch: peripheral and central sensitization	24
Bioenergetics of the VO2 slow component between exercise intensity domains	24
Channelopathies of voltage-gated L-type Cav1.3/α1D and T-type Cav3.1/α1G Ca2+ channels in dysfunction of heart automaticity	23
Structure and dynamics of photoreceptor sensory cilia	23
Potassium homeostasis: sensors, mediators, and targets	22
The regulation of FGF23 under physiological and pathophysiological conditions	22
Cav1.2 channelopathies causing autism: new hallmarks on Timothy syndrome	22
Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy	22
Renal blood flow and oxygenation	22
Cardiac small-conductance calcium-activated potassium channels in health and disease	21
Biochemistry and physiology of zebrafish photoreceptors	20
Interplay between bioenergetics and oxidative stress at normal brain aging. Aging as a result of increasing disbalance in the system oxidative stress–energy provision	19
Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection	19
Changes in sleep EEG with aging in humans and rodents	19
CNG channel structure, function, and gating: a tale of conformational flexibility	19
Rare CACNA1A mutations leading to congenital ataxia	18
A detailed characterization of the hyperpolarization-activated “funny” current (If) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity	18
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice	18
Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology	18
Glucose transport in lymphocytes	17
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption	17
The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation	17
Keeping the ageing brain wired: a role for purine signalling in regulating cellular metabolism in oligodendrocyte progenitors	17
Kidney metabolism and acid–base control: back to the basics	17
Plant glucose transporter structure and function	16
Intracellular Cl− dysregulation causing and caused by pathogenic neuronal activity	16
Physiological relevance of proton-activated GPCRs	16
Sirtuin 1 and endothelial glycocalyx	16
Phosphate intake, hyperphosphatemia, and kidney function	16
Atrial fibrillation rhythm is associated with marked changes in metabolic and myofibrillar protein expression in left atrial appendage	16
Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones	16
MiR-155 inhibition alleviates suppression of osteoblastic differentiation by high glucose and free fatty acids in human bone marrow stromal cells by upregulating SIRT1	16
Upregulation of transient receptor potential melastatin 4 (TRPM4) in ventricular fibroblasts from heart failure patients	14
Erythroid glucose transport in health and disease	14
TRPA1 gene variants hurting our feelings	14
Benzophenanthridine alkaloids suppress lung adenocarcinoma by blocking TMEM16A Ca2+-activated Cl− channels	14
Voltage-dependent CaV3.2 and CaV2.2 channels in nociceptive pathways	14
TRPM4 non-selective cation channel in human atrial fibroblast growth	14
The role of calcium homeostasis remodeling in inherited cardiac arrhythmia syndromes	14
TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei	14
Nobel somatosensations and pain	13
Regulation of cardiovascular calcium channel activity by post-translational modifications or interacting proteins	13
Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells	13

Ca2+ mishandling and mitochondrial dysfunction: a converging road to prediabetic and diabetic cardiomyopathy	13
Regulation of retinal membrane guanylyl cyclase (RetGC) by negative calcium feedback and RD3 protein	13
Defective autophagy in vascular smooth muscle cells increases passive stiffness of the mouse aortic vessel wall	13
SLC9A4 in the organum vasculosum of the lamina terminalis is a [Na+] sensor for the control of water intake	13
Tissue chaperoning—the expanded functions of fetuin-A beyond inhibition of systemic calcification	13
Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells	13
Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine	12
Sex difference in kidney electrolyte transport III: Impact of low K intake on thiazide-sensitive cation excretion in male and female mice	12
Mechanisms underlying pathological Ca2+ handling in diseases of the heart	12
Direct monitoring of ER Ca2+ dynamics reveals that Ca2+ entry induces ER-Ca2+ release in astrocytes	12
Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC	12
Cav1.4 dysfunction and congenital stationary night blindness type 2	12
Is carbonyl/AGE/RAGE stress a hallmark of the brain aging?	12
MiR-221-3p regulates the microvascular dysfunction in diabetic retinopathy by targeting TIMP3	12
Olfactory impairment in men and mice related to aging and amyloid-induced pathology	12
Cav2.3 R-type calcium channels: from its discovery to pathogenic de novo CACNA1E variants: a historical perspective	12
Spontaneous recovery, time course, and circadian influence on habituation of the cardiovascular responses to repeated restraint stress in rats	12
Towards the clinical translation of optogenetic skeletal muscle stimulation	11
TASK channels: channelopathies, trafficking, and receptor-mediated inhibition	11
Role of vitamins in the metabolic syndrome and cardiovascular disease	11
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking	11
MiRNA-190 exerts neuroprotective effects against ischemic stroke through Rho/Rho-kinase pathway	11
Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway	11
Functional subgroups of rat and human sensory neurons: a systematic review of electrophysiological properties	11
Presynaptic GABAB receptor–mediated network excitation in the medial prefrontal cortex of Tsc2+/- mice	11
UMOD and the architecture of kidney disease	11
The TRPV3 channel of the bovine rumen: localization and functional characterization of a protein relevant for ruminal ammonia transport	11
Soluble αKlotho downregulates Orai1-mediated store-operated Ca2+ entry via PI3K-dependent signaling	11
Cellular and systemic mechanisms for glucose sensing and homeostasis	11
Regulation of mitochondrial temperature in health and disease	10
Single nephron glomerular filtration rate measured by linescan multiphoton microscopy compared to conventional micropuncture	10
DCLK1 inhibition attenuates tumorigenesis and improves chemosensitivity in esophageal squamous cell carcinoma by inhibiting β-catenin/c-Myc signaling	10
Olfactory signals from the main olfactory bulb converge with taste information from the chorda tympani nerve in the agranular insular cortex of rats	10
Cardiac adaptation and cardioprotection against arrhythmias and ischemia-reperfusion injury in mammalian hibernators	10
Peripheral receptors and neuromediators involved in the antihyperalgesic effects of acupuncture: a state-of-the-art review	10
The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise	10
Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation	10
14–3-3 protein regulation of excitation–contraction coupling	10
Excitation-contraction coupling and calcium release in atrial muscle	9
Light responses of mammalian cones	9
Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and KCa3.1 ion channels, but involves phosphoinositide 3-kinase	9
Elevated ROS depress mitochondrial oxygen utilization efficiency in cardiomyocytes during acute hypoxia	9
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability	9
Acute intracerebroventricular injection of chemerin-9 increases systemic blood pressure through activating sympathetic nerves via CMKLR1 in brain	9
Fount, fate, features, and function of renal erythropoietin-producing cells	9
Respiratory influence on brain dynamics: the preponderant role of the nasal pathway and deep slow regime	9
Increasing whole-body energetic stress does not augment fasting-induced changes in human skeletal muscle	9
Functional compartmentalization of photoreceptor neurons	9
Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels	9
Lipid metabolic reprogramming by hypoxia-inducible factor-1 in the hypoxic tumour microenvironment	9
Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex	8
Importance of evaluating protein glycosylation in pluripotent stem cell-derived cardiomyocytes for research and clinical applications	8
Adaptive response of the murine collecting duct to alkali loading	8
Bicarbonate permeation through anion channels: its role in health and disease	8
Characterisation of the static offset in the travelling wave in the cochlear basal turn	8
Protection of kidney function and tissue integrity by pharmacologic use of natriuretic peptides and neprilysin inhibitors	8
The importance of kidney calcium handling in the homeostasis of extracellular fluid calcium	8
Structural aspects of rod opsin and their implication in genetic diseases	8
Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis	8
( −)-Epicatechin and cardiometabolic risk factors: a focus on potential mechanisms of action	8
Controlling neuronal assemblies: a fundamental function of respiration-related brain oscillations in neuronal networks	8
Decreased KLHL3 expression is involved in the activation of WNK-OSR1/SPAK-NCC cascade in type 1 diabetic mice	8
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity	8
Respiratory entrainment of units in the mouse parietal cortex depends on vigilance state	8
Electrophysiological characterization of ectopic spontaneous discharge in axotomized and intact fibers upon nerve transection: a role in spontaneous pain?	7
Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling	7
An alternative pathway for sweet sensation: possible mechanisms and physiological relevance	7
Neurogenic tachykinin mechanisms in experimental nephritis of rats	7
The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule	7
Impact of intracellular hemin on N-type inactivation of voltage-gated K+ channels	7
Carbonic anhydrase IX and hypoxia-inducible factor 1 attenuate cardiac dysfunction after myocardial infarction	7
Tuft cell integration of luminal states and interaction modules in tissues	7
Slow recovery from the inactivation of voltage-gated sodium channel Nav1.3 in mouse taste receptor cells	7
Propagation of spontaneous electrical activity in the ex vivo human uterus	7
A special issue on glucose transporters in health and disease	7
The bile acid-sensitive ion channel (BASIC) mediates bile acid-dependent currents in bile duct epithelial cells	7
β-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia	7
E-cigarette effects on vascular function in animals and humans	7
Roles of glutamate and GABA of the Kölliker-Fuse nucleus in generating the cardiovascular chemoreflex	7
Breathing modulates gamma synchronization across species	7

Ventrolateral periaqueductal gray matter integrative system of defense and antinociception	7
Flexible and multifaceted: the plasticity of renin-expressing cells	7
SOCE in the cardiomyocyte: the secret is in the chambers	7
Metabolic mechanisms of acute proximal tubular injury	7
The anion exchanger PAT-1 (Slc26a6) does not participate in oxalate or chloride transport by mouse large intestine	7
Regulation of CaV3.2 channels by the receptor for activated C kinase 1 (Rack-1)	7
Stimulation of ORAI1 expression, store-operated Ca2+ entry, and osteogenic signaling by high glucose exposure of human aortic smooth muscle cells	7
Ion channelopathies to bridge molecular lesions, channel function, and clinical therapies	6
Vascularisation of pluripotent stem cell–derived myocardium: biomechanical insights for physiological relevance in cardiac tissue engineering	6
Proteolytic ENaC activation in health and disease—a complicated puzzle	6
Promotion of aging heart function and its redox balance following hind-limb blood flow restriction plus endurance exercise training in rats: klotho and PGC1-α as involving candidate molecules	6
Comparative lipid profiling of murine and human atherosclerotic plaques using high-resolution MALDI MSI	6
Activation of farnesoid X receptor (FXR) induces crystallin zeta expression in mouse medullary collecting duct cells	6
Expression of serotonin receptor HTR4 in glucagon-like peptide-1-positive enteroendocrine cells of the murine intestine	6
Chamber-specific regulation of atrial natriuretic peptide secretion in cardiac hypertrophy: atrial wall dynamics in the ANP secretion	6
TRPV4 and TRPM8 as putative targets for chronic low back pain alleviation	6
A5 noradrenergic neurons and breathing control in neonate rats	6
Cell surface markers for immunophenotyping human pluripotent stem cell-derived cardiomyocytes	6
Cereblon: promise and challenges for combating human diseases	6
Functional expression of mitochondrial KCa3.1 channels in non-small cell lung cancer cells	6
Influence of layer separation on the determination of stomach smooth muscle properties	6
Mineralocorticoid receptor-antagonism prevents COVID-19-dependent glycocalyx damage	6
Lithium enhances exercise-induced glycogen breakdown and insulin-induced AKT activation to facilitate glucose uptake in rodent skeletal muscle	6
The medial prefrontal cortex and the cardiac baroreflex activity: physiological and pathological implications	6
Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system	6
Metabolic instability vs fibre recruitment contribution to the $${\dot{V}O_2}$$ slow component in different exercise intensity domains	6
Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain	6
Alterations of housekeeping proteins in human aged and diseased hearts	6
Improved adaptation to physical stress in mice overexpressing SUR2A is associated with changes in the pattern of Q-T interval	6
Renal water transport in health and disease	6
Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart	5
Dynamics of neocortical networks: connectivity beyond the canonical microcircuit	5
Primary culture of the rat spinal dorsal horn: a tool to investigate the effects of inflammatory stimulation on the afferent somatosensory system	5
MicroRNA-1246 regulates proliferation, invasion, and differentiation in human vascular smooth muscle cells by targeting cystic fibrosis transmembrane conductance regulator (CFTR)	5
TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity	5
Fetuin-B regulates vascular plaque rupture via TGF-β receptor-mediated Smad pathway in vascular smooth muscle cells	5
Oxygen-dependent regulation of ion channels: acute responses, post-translational modification, and response to chronic hypoxia	5
Mechanisms of ion transport regulation by HNF1β in the kidney: beyond transcriptional regulation of channels and transporters	5
tDCS effects on brain network properties during physiological aging	5
Interphotoreceptor coupling: an evolutionary perspective	5
The role of adrenergic and muscarinic receptors in stress-induced cardiac injury	5
The regulation of the small-conductance calcium-activated potassium current and the mechanisms of sex dimorphism in J wave syndrome	5
Alcohol metabolite acetic acid activates BK channels in a pH-dependent manner and decreases calcium oscillations and exocytosis of secretory granules in rat pituitary GH3 cells	5
Where vision begins	5
Potentiation of force by extracellular potassium and posttetanic potentiation are additive in mouse fast-twitch muscle in vitro	5
Beyond Ca2+ signalling: the role of TRPV3 in the transport of NH4+	5
(H)IF applicable: promotion of neurogenesis by induced HIF-2 signalling after ischaemia	5
Human pluripotent stem cell–based cardiovascular disease modeling and drug discovery	5
Simulating cardiac Ca2+ release units: effects of RyR cluster size and Ca2+ buffers on diastolic Ca2+ leak	5
Regulation of endothelial function by cigarette smoke and next-generation tobacco and nicotine products	5
Myostatin regulates the production of fibroblast growth factor 23 (FGF23) in UMR106 osteoblast–like cells	5
AFM-based nanoindentation indicates an impaired cortical stiffness in the AAV-PCSK9DY atherosclerosis mouse model	5
Left ventricular depression and pulmonary edema in rats after short-term normobaric hypoxia: effects of adrenergic blockade and reduced fluid load	5
Electroacupuncture decreases inflammatory pain through a pro-resolving mechanism involving the peripheral annexin A1-formyl peptide receptor 2/ALX-opioid receptor pathway	5
Towards bridging the translational gap by improved modeling of human nociception in health and disease	5
Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia	5
L-cysteine modulates visceral nociception mediated by the CaV2.3 R-type calcium channels	5
Connexin mRNA distribution in adult mouse kidneys	5
MiR-10b-3p alleviates cerebral ischemia/reperfusion injury by targeting Krüppel-like factor 5 (KLF5)	5
TRIC-A regulates intracellular Ca2+ homeostasis in cardiomyocytes	5
Low voltage-activated channels in rat pulmonary vein cardiomyocytes: coexistence of a non-selective cationic channel and of T-type Ca channels	4
Modulation of inspiratory burst duration and frequency by bombesin in vitro	4
The role of acrolein for E-cigarette vapour condensate mediated activation of NADPH oxidase in cultured endothelial cells and macrophages	4
One hundred years from Otto Loewi experiment, a dream that revolutionized our view of neurotransmission	4
Two firing modes and well-resolved Na+, K+, and Ca2+ currents at the cell-microelectrode junction of spontaneously active rat chromaffin cell on MEAs	4
Comparative study of the effects of cigarette smoke versus next-generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes	4
Is curvature of the force-velocity relationship affected by oxygen availability? Evidence from studies in ex vivo and in situ rat muscles	4
Multisite phosphorylation of the cardiac ryanodine receptor: a random or coordinated event?	4
A novel mutation in KCNH2 yields loss-of-function of hERG potassium channel in long QT syndrome 2	4
Acute reversible SERCA blockade facilitates or blocks exocytosis, respectively in mouse or bovine chromaffin cells	4
Preclinical pharmacological in vitro investigations on low chloride conductance myotonia: effects of potassium regulation	4
Supramolecular organization of rhodopsin in rod photoreceptor cell membranes	4
Role of natriuretic peptides in the cardiovascular-adipose communication: a tale of two organs	4
Platinum accumulation in the brain and alteration in the central regulation of cardiovascular and respiratory functions in oxaliplatin-treated rats	4
Editing of the myosin phosphatase regulatory subunit suppresses angiotensin II induced hypertension via sensitization to nitric oxide mediated vasodilation	4
Endothelin receptors in renal interstitial cells do not contribute to the development of fibrosis during experimental kidney disease	4
Investigation into the difference in mitochondrial-cytosolic calcium coupling between adult cardiomyocyte and hiPSC-CM using a novel multifunctional genetic probe	4
Relevance of mitochondrial dysfunction in heart disease associated with insulin resistance conditions	4
Impact of the glutamatergic neurotransmission within the A5 region on the cardiorespiratory response evoked from the midbrain dlPAG	4
Exercise and vascular function in sedentary lifestyles in humans	4
Dopamine D4 receptor subtype activation reduces the rat cardiac parasympathetic discharge	4
Enhancement of airway ciliary beating mediated via voltage-gated Ca2+ channels/α7-nicotinic receptors in mice	4
Impaired thermoregulation in spontaneously hypertensive rats during physical exercise is related to reduced hypothalamic neuronal activation	4
Electrophysiological characterization of a CaV3.1 calcium channel mutation linked to trigeminal neuralgia	4
Ion channel long non-coding RNAs in neuropathic pain	4
Sexually dimorphic effects of prenatal diazepam exposure on respiratory control and the monoaminergic system of neonate and young rats	4
Differential modulation of active expiration during hypercapnia by the medullary raphe in unanesthetized rats	4
Inhibition of big-conductance Ca2+-activated K+ channels in cerebral artery (vascular) smooth muscle cells is a major novel mechanism for tacrolimus-induced hypertension	4
Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?	4
Expression of phosphate and calcium transporters and their regulators in parotid glands of mice	3
Water intake releases serotonin from enterochromaffin cells in rat jejunal villi	3
High-fat diet-induced mitochondrial dysfunction is associated with loss of protection from ischemic preconditioning in renal ischemia reperfusion	3
Ventromedial prefrontal cortex CRF1 receptors modulate the tachycardic activity of baroreflex	3
Further evidence against the role renal medullary perfusion in short-term control of arterial pressure in normotensive and mildly or overtly hypertensive rats	3
Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker	3