Pediatric Research

Article	Citations
The role of integrins in inflammation and angiogenesis	142
Coronavirus disease 2019 (COVID-19) in children and/or adolescents: a meta-analysis	136
The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling	103
Pulmonary hypertension in bronchopulmonary dysplasia	94
COVID-19 impact on research, lessons learned from COVID-19 research, implications for pediatric research	84
Challenges in developing a consensus definition of neonatal sepsis	77
Tackling healthcare access barriers for individuals with autism from diagnosis to adulthood	72
COVID-19 in children and altered inflammatory responses	70
Defining necrotizing enterocolitis: current difficulties and future opportunities	69
Things must not fall apart: the ripple effects of the COVID-19 pandemic on children in sub-Saharan Africa	65
Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome	59
Social determinants of health and outcomes for children and adults with congenital heart disease: a systematic review	57
Neonatal sepsis: need for consensus definition, collaboration and core outcomes	57
COVID-19 PICU guidelines: for high- and limited-resource settings	55
Prevention of iron deficiency anemia in infants and toddlers	52
International comparison of guidelines for managing neonates at the early phase of the SARS-CoV-2 pandemic	50
Neonates and COVID-19: state of the art	50
Diagnosis of neonatal sepsis: the past, present and future	50
Social determinants of health and child maltreatment: a systematic review	48
The influence of social determinants of health on the genetic diagnostic odyssey: who remains undiagnosed, why, and to what effect?	47
The social ecology of childhood and early life adversity	46
Chorioamnionitis and neonatal outcomes	45
Preterm white matter injury: ultrasound diagnosis and classification	44
State-of-the-art neonatal cerebral ultrasound: technique and reporting	40
Racial and socioeconomic disparities in breast milk feedings in US neonatal intensive care units	39

Role of zinc in neonatal growth and brain growth: review and scoping review	39
The NIH ECHO Program: investigating how early environmental influences affect child health	38
Defining pediatric asthma: phenotypes to endotypes and beyond	38
Possible causes for decreased susceptibility of children to coronavirus	37
A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children	37
Prenatal opioid exposure is associated with smaller brain volumes in multiple regions	36
Screen media exposure in the first 2 years of life and preschool cognitive development: a longitudinal study	34
Predicting the outcomes of preterm neonates beyond the neonatal intensive care unit: What are we missing?	33
Antibiotics at birth and later antibiotic courses: effects on gut microbiota	33
The Sarnat score for neonatal encephalopathy: looking back and moving forward	32
Antenatal corticosteroids: a reappraisal of the drug formulation and dose	32
Evidence for maternal diet-mediated effects on the offspring microbiome and immunity: implications for public health initiatives	32
No infectious SARS-CoV-2 in breast milk from a cohort of 110 lactating women	32
Physical activity modification in youth with congenital heart disease: a comprehensive narrative review	31
Human breast milk-derived exosomes may help maintain intestinal epithelial barrier integrity	30
Oropharyngeal colostrum therapy reduces the incidence of ventilator-associated pneumonia in very low birth weight infants: a systematic review and meta-analysis	30
Challenges in diagnosing necrotizing enterocolitis	30
Trends in clinical presentation of children with COVID-19: a systematic review of individual participant data	29
Growth and changes in the pediatric medical subspecialty workforce pipeline	29
Early probiotic supplementation with B. infantis in breastfed infants leads to persistent colonization at 1 year	29
Neonatal sepsis definitions from randomised clinical trials	29
Psychological risks to mother–infant bonding during the COVID-19 pandemic	29
Neonatal multidrug-resistant gram-negative infection: epidemiology, mechanisms of resistance, and management	28
Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management	28
Influence of race/ethnicity and income on the link between adverse childhood experiences and child flourishing	28
Shoring up the safety net for children in the COVID-19 pandemic	27
Severe acute kidney injury in neonates with necrotizing enterocolitis: risk factors and outcomes	27
SPR perspectives: Environmental influences on Child Health Outcomes (ECHO) Program: overcoming challenges to generate engaged, multidisciplinary science	27
Cannabis use and measurement of cannabinoids in plasma and breast milk of breastfeeding mothers	26
Risk profiles of severe illness in children with COVID-19: a meta-analysis of individual patients	25
Systemic inflammatory syndrome in COVID-19–SISCoV study: systematic review and meta-analysis	25
Continuous glucose monitoring profile during therapeutic hypothermia in encephalopathic infants with unfavorable outcome	25
Placental programming, perinatal inflammation, and neurodevelopment impairment among those born extremely preterm	24
Diagnostic and predictive value of Doppler ultrasound for evaluation of the brain circulation in preterm infants: a systematic review	23
Close Collaboration with Parents intervention improves family-centered care in different neonatal unit contexts: a pre–post study	23
Family integrated care in single family rooms for preterm infants and late-onset sepsis: a retrospective study and mediation analysis	23
Human milk oligosaccharides, infant growth, and adiposity over the first 4 months of lactation	22
Human milk feeding and cognitive outcome in preterm infants: the role of infection and NEC reduction	22
Noninvasive optical measurement of microvascular cerebral hemodynamics and autoregulation in the neonatal ECMO patient	22
Vital signs as physiomarkers of neonatal sepsis	22
The difference of the inflammatory milieu in MIS-C and severe COVID-19	22
Neuroplacentology in congenital heart disease: placental connections to neurodevelopmental outcomes	22
Screen time and developmental and behavioral outcomes for preschool children	22
Exposure to Δ9-tetrahydrocannabinol during rat pregnancy leads to impaired cardiac dysfunction in postnatal life	22
SARS-CoV-2 vaccine testing and trials in the pediatric population: biologic, ethical, research, and implementation challenges	21
Unintended consequences of restrictive visitation policies during the COVID-19 pandemic: implications for hospitalized children	21
SARS-CoV-2 infection in children and implications for vaccination	21
The impact of COVID-19 on paediatric emergency department visits. A one-year retrospective study	21
Brain injury in preterm infants with surgical necrotizing enterocolitis: clinical and bowel pathological correlates	21
Pediatric inflammatory bowel disease and the effect of COVID-19 pandemic on treatment adherence and patients’ behavior	21

Nanomedicine and graphene-based materials: advanced technologies for potential treatments of diseases in the developing nervous system	20
Maternal diabetes alters microRNA expression in fetal exosomes, human umbilical vein endothelial cells and placenta	20
Pediatric subspecialty telemedicine use from the patient and provider perspective	20
Diagnostic methods for neonatal hyperbilirubinemia: benefits, limitations, requirements, and novel developments	20
Incidence rates and characteristics of pediatric onset psychogenic nonepileptic seizures	20
The development and validation of a cerebral ultrasound scoring system for infants with hypoxic-ischaemic encephalopathy	20
Near-infrared spectroscopy as a diagnostic tool for necrotizing enterocolitis in preterm infants	20
Caffeine treatment started before injury reduces hypoxic–ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization	20
Metabolic-endocrine disruption due to preterm birth impacts growth, body composition, and neonatal outcome	19
“Racism as a public health issue” APS racism series: at the intersection of equity, science, and social justice	19
Vitamin A deficiency increases the risk of gastrointestinal comorbidity and exacerbates core symptoms in children with autism spectrum disorder	19
Effects of physical activity interventions on cognitive performance of overweight or obese children and adolescents: a systematic review and meta-analysis	19
Impact of integrated clinical decision support systems in the management of pediatric acute kidney injury: a pilot study	19
Exhaled volatile organic compounds analysis in clinical pediatrics: a systematic review	19
Spontaneous preterm delivery is reflected in both early neonatal and maternal gut microbiota	19
Neonates in the COVID-19 pandemic	19
Artificial intelligence-based clinical decision support in pediatrics	19
Peripheral immune cells and perinatal brain injury: a double-edged sword?	19
Human milk immunomodulatory proteins are related to development of infant body composition during the first year of lactation	19
Access to pediatric subspecialty care for children and youth: possible shortages and potential solutions	19
Acute-on-chronic stress in the time of COVID-19: assessment considerations for vulnerable youth populations	18
Multiomics, artificial intelligence, and precision medicine in perinatology	18
Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis	18
Transfusions and neurodevelopmental outcomes in extremely low gestation neonates enrolled in the PENUT Trial: a randomized clinical trial	18
Early oxygen levels contribute to brain injury in extremely preterm infants	18
The prevalence of ankyloglossia in children aged <1 year: a systematic review and meta-analysis	18
Surgery requiring general anesthesia in preterm infants is associated with altered brain volumes at term equivalent age and neurodevelopmental impairment	18
Safety and efficacy of probiotic administration to preterm infants: ten common questions	18
The relationship between dog ownership, dog play, family dog walking, and pre-schooler social–emotional development: findings from the PLAYCE observational study	18
Altered microbiomes in thirdhand smoke-exposed children and their home environments	18
Incidence of diabetic ketoacidosis during COVID-19 pandemic: a meta-analysis of 124,597 children with diabetes	18
Association of blood pressure, obesity and physical activity with arterial stiffness in children: a systematic review and meta-analysis	18
Idiopathic nephrotic syndrome in children: role of regulatory T cells and gut microbiota	18
Parents’ ratings of post-discharge healthcare for their children born very preterm and their suggestions for improvement: a European cohort study	18
Hidden etiology of cerebral palsy: genetic and clinical heterogeneity and efficient diagnosis by next-generation sequencing	18
Neuroprotective therapies in the NICU in term infants: present and future	18
Sex-specific relationships of the infant microbiome and early-childhood behavioral outcomes	17
TLR4 regulates ROS and autophagy to control neutrophil extracellular traps formation against Streptococcus pneumoniae in acute otitis media	17
Rapid exome sequencing in PICU patients with new-onset metabolic or neurological disorders	17
The sixth revolution in pediatric vaccinology: immunoengineering and delivery systems	17
Altered brain metabolism contributes to executive function deficits in school-aged children born very preterm	17
Effects of physical therapy on lung function in children with asthma: a systematic review and meta-analysis	17
Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children	17
Hemodynamic dysfunction in neonatal sepsis	17
Associations of media use and early childhood development: cross-sectional findings from the LIFE Child study	17
Neonatal blood culture inoculant volume: feasibility and challenges	17
Screening methods for neonatal hyperbilirubinemia: benefits, limitations, requirements, and novel developments	17
Early development of sleep and brain functional connectivity in term-born and preterm infants	17
Compassion fatigue, burnout, and compassion satisfaction in pediatric subspecialists during the SARS-CoV-2 pandemic	16
Pediatric sepsis screening in US hospitals	16
Early pediatric chronic kidney disease is associated with brain volumetric gray matter abnormalities	16
The importance of trustworthiness: lessons from the COVID-19 pandemic	16
Predictors of non-alcoholic fatty liver disease in children	16
Aminophylline for renal protection in neonatal hypoxic–ischemic encephalopathy in the era of therapeutic hypothermia	16
D3-creatine dilution for the noninvasive measurement of skeletal muscle mass in premature infants	16
Cerebral oxygen saturation and autoregulation during hypotension in extremely preterm infants	16
Invasive fungal infections in neonates: a review	16
Circulating high-sensitivity troponin T and microRNAs as markers of myocardial damage during childhood leukaemia treatment	16
Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade	16
Respiratory muscle function in the newborn: a narrative review	16
Cerebral near-infrared spectroscopy monitoring (NIRS) in children and adults: a systematic review with meta-analysis	16
Comparison of IVIG resistance predictive models in Kawasaki disease	16
Cause of preterm birth and late-onset sepsis in very preterm infants: the EPIPAGE-2 cohort study	16
Repeatability of transient elastography in children	16
SPR Perspectives: scientific opportunities in the Environmental influences on Child Health Outcomes Program	15
Incomplete resection of necrotic bowel may increase mortality in infants with necrotizing enterocolitis	15
Plasma vasopressin levels are closely associated with fetal hypotension and neuronal injury after hypoxia-ischemia in near-term fetal sheep	15
Clinical phenotypes of acute kidney injury are associated with unique outcomes in critically ill septic children	15
Dramatic changes in blood protein levels during the first week of life in extremely preterm infants	15
Autonomic development in preterm infants is associated with morbidity of prematurity	15
Towards personalized medicine in maternal and child health: integrating biologic and social determinants	15
Using machine learning to impact on long-term clinical care: principles, challenges, and practicalities	15
Gestational age-dependent development of the neonatal metabolome	15
Determinants of neurological outcome in neonates with congenital heart disease following heart surgery	15
Validation of the pediatric stroke outcome measure for classifying overall neurological deficit	15
Do preterm girls need different nutrition to preterm boys? Sex-specific nutrition for the preterm infant	15
Established severe BPD: is there a way out? Change of ventilatory paradigms	15
Persistent organic pollutants in pregnant women potentially affect child development and thyroid hormone status	15
A critical evaluation of current definitions of necrotizing enterocolitis	14
Role of platelets in neonatal necrotizing enterocolitis	14

Rho/SMAD/mTOR triple inhibition enables long-term expansion of human neonatal tracheal aspirate-derived airway basal cell-like cells	14
Social epidemiology of early adolescent problematic screen use in the United States	14
Perspectives from the Society for Pediatric Research. Neonatal encephalopathy clinical trials: developing the future	14
Respiratory, growth, and survival outcomes of infants with tracheostomy and ventilator dependence	14
Risk factors for recurrent respiratory tract infection in preschool-aged children	14
Dairy product intake decreases bone resorption following a 12-week diet and exercise intervention in overweight and obese adolescent girls	14
Lung function between 8 and 15 years of age in very preterm infants with fetal growth restriction	14
Retrospective analysis of epidemic thunderstorm asthma in children in Yulin, northwest China	14
Analgesia for fetal pain during prenatal surgery: 10 years of progress	14
Antenatal N-acetylcysteine to improve outcomes of premature infants with intra-amniotic infection and inflammation (Triple I): randomized clinical trial	14
Placental origins of neonatal diseases: toward a precision medicine approach	14
The use of machine learning and artificial intelligence within pediatric critical care	14
Racial and ethnic disparities in adult COVID-19 and the future impact on child health	14
Multichannel EEG abnormalities during the first 6 hours in infants with mild hypoxic–ischaemic encephalopathy	14
T-piece resuscitator or self-inflating bag during neonatal resuscitation: a scoping review	14
Iron transport across the human placenta is regulated by hepcidin	14
The effect of gestational age on major neurodevelopmental disorders in preterm infants	14
The newborn metabolome: associations with gestational diabetes, sex, gestation, birth mode, and birth weight	13
Pediatric sepsis biomarkers for prognostic and predictive enrichment	13
High incidence of stroke and mortality in pediatric critical care patients with COVID-19 in Peru	13
Inflammation in children with cystic fibrosis: contribution of bacterial production of long-chain fatty acids	13
What COVID-19 means for non-neurotypical children and their families	13
Pandemic beyond the virus: maternal COVID-related postnatal stress is associated with infant temperament	13
Carbon dioxide levels in neonates: what are safe parameters?	13
Fluid status in the first 10 days of life and death/bronchopulmonary dysplasia among preterm infants	13
European consensus recommendations for neonatal and paediatric retrievals of positive or suspected COVID-19 patients	13
Sex-specific cytokine responses and neurocognitive outcome after blood transfusions in preterm infants	13
Body composition of extremely preterm infants fed protein-enriched, fortified milk: a randomized trial	13
Gene signature of children with severe respiratory syncytial virus infection	13
Short exposure to hyperoxia causes cultured lung epithelial cell mitochondrial dysregulation and alveolar simplification in mice	13
Autism spectrum disorder and severe social impairment associated with elevated plasma interleukin-8	13
Neonatal acute kidney injury risk stratification score: STARZ study	13
Patent ductus arteriosus, tracheal ventilation, and the risk of bronchopulmonary dysplasia	13
Where to make a difference: research and the social determinants in pediatrics and child health in the COVID-19 era	13
The hidden consequence of intraventricular hemorrhage: persistent cerebral desaturation after IVH in preterm infants	13
Epigenetic regulation of pediatric and neonatal immune responses	13
Hydrogen and therapeutic gases for neonatal hypoxic–ischemic encephalopathy: potential neuroprotective adjuncts in translational research	13
Early development of the skin microbiome: therapeutic opportunities	13
Mechanisms and modulation of sepsis-induced immune dysfunction in children	13
Heart rate variability spectrum characteristics in children with sleep apnea	13
Racial/ethnic disparities and human milk use in necrotizing enterocolitis	13
Should less invasive surfactant administration (LISA) become routine practice in US neonatal units?	13
Continuous chest compressions with asynchronous ventilations increase carotid blood flow in the perinatal asphyxiated lamb model	13
Infants exposed to antibiotics after birth have altered recognition memory responses at one month of age	12
Hirschsprung’s disease: key microRNAs and target genes	12
Gut priming with bovine colostrum and T regulatory cells in preterm neonates: a randomized controlled trial	12
Mild hypoxic-ischemic encephalopathy (HIE): timing and pattern of MRI brain injury	12
Ultrasound of acquired posterior fossa abnormalities in the newborn	12
Multi-parametric MRI of kidney disease progression for autosomal recessive polycystic kidney disease: mouse model and initial patient results	12
Cerebellar injury in term neonates with hypoxic–ischemic encephalopathy is underestimated	12
Gut microbiome and attention deficit/hyperactivity disorder: a systematic review	12
Bronchopulmonary dysplasia precursors influence risk of white matter injury and adverse neurodevelopmental outcome in preterm infants	12
Thromboembolism in children with multisystem inflammatory syndrome: a literature review	12
Associations between neurofilament light-chain protein, brain structure, and chronic kidney disease	12
Long-term, low-dose macrolide antibiotic treatment in pediatric chronic airway diseases	12
Predicting polysomnographic severity thresholds in children using machine learning	12
Pediatric central venous access devices: practice, performance, and costs	12
Neonatal hyperbilirubinemia and bilirubin neurotoxicity in hospitalized neonates: analysis of the US Database	12
Nitric oxide and the brain. Part 1: Mechanisms of regulation, transport and effects on the developing brain	12
Regional splanchnic oxygen saturation for preterm infants in the first week after birth: reference values	12
Utility of volatile organic compounds as a diagnostic tool in preterm infants	12
Electrocardiogram for heart rate evaluation during preterm resuscitation at birth: a randomized trial	12
Vitamin therapy in sepsis	12
Early prediction of neurodevelopmental outcomes at 12 years in children born extremely preterm	12
Sensory-based interventions in the NICU: systematic review of effects on preterm brain development	12
Treatment of severe Kaposiform lymphangiomatosis positive for NRAS mutation by MEK inhibition	12
PROMPT intervention for children with severe speech motor delay: a randomized control trial	12
Blood protein profiles related to preterm birth and retinopathy of prematurity	12
Visual attention during pediatric resuscitation with feedback devices: a randomized simulation study	12
Post-hemorrhagic ventricular dilatation: inter-observer reliability of ventricular size measurements in extremely preterm infants	12
Effects of vitamin D supplementation on circulating concentrations of growth factors and immune-mediators in healthy women during pregnancy	11
Brain inflammation and injury at 48 h is not altered by human amnion epithelial cells in ventilated preterm lambs	11
Controversy: The evolving science of fluoride: when new evidence doesn’t conform with existing beliefs	11
Surfactant lung delivery with LISA and InSurE in adult rabbits with respiratory distress	11
Uric acid reference values: report on 1750 healthy Brazilian children and adolescents	11
Circ-ITCH overexpression promoted cell proliferation and migration in Hirschsprung disease through miR-146b-5p/RET axis	11
Background media use is negatively related to language and literacy skills: indirect effects of self-regulation	11
Sleep-disordered breathing and sleep macro- and micro-architecture in children with Down syndrome	11
Neonatal outcomes during the COVID-19 pandemic in New York City	11
Odor identification performance in children aged 3–6 years	11
Paediatric and neonatal sepsis and inflammation	11
Isolated diastolic high blood pressure: a distinct clinical phenotype in US children	11
A new era: improving use of sociodemographic constructs in the analysis of pediatric cohort study data	11
Congenital chloride diarrhea clinical features and management: a systematic review	11
Serum cytokine profiles in infants with infantile hemangiomas on oral propranolol treatment: VEGF and bFGF, potential biomarkers predicting clinical outcomes	11
Congenital heart disease in school-aged children: Cognition, education, and participation in leisure activities	11
Cardiovascular management following hypoxic–ischemic encephalopathy in North America: need for physiologic consideration	11
The unmet clinical needs of children with developmental coordination disorder	11
Lactoferrin for iron-deficiency anemia in children with inflammatory bowel disease: a clinical trial	11
Early brain and abdominal oxygenation in extremely low birth weight infants	11
ADHD symptoms and diagnosis in adult preterms: systematic review, IPD meta-analysis, and register-linkage study	11
Impact of pertussis-specific IgA, IgM, and IgG antibodies in mother’s own breast milk and donor breast milk during preterm infant digestion	11
Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency	10
Genome-wide association study identifies a novel maternal gene × stress interaction associated with spontaneous preterm birth	10
Childhood obesity and adverse cardiometabolic risk in large for gestational age infants and potential early preventive strategies: a narrative review	10