OOIR: Observatory of International Research

Papers

(The TQCC of Panminerva Medica is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Study on the cleaning effect of heavily polluted instrument cleaners on energy instruments in the manual brush-free cleaning process	30
Efficacy of hypofractionated radiotherapy combined with docetaxel in middle and advanced non-small cell lung cancer and its effects on serum MMP-9 and VEGF expressions	29
Effects of MiR-34a on the proliferation and apoptosis of osteoarthritis chondrocytes via the ERK1/2 pathway	27
Thymosin α1 alleviates lung injury in sepsis rats via Notch signaling pathway	25
Can selective serotonin reuptake inhibitors/serotonin and norepinephrine reuptake inhibitor antidepressants decrease the "cytokine storm" in the course of COVID-19 pneumonia?	22
Analysis of prenatal value of ultrasonography in diagnosis of fetal malformation in early pregnancy	22
Exploration on the recovery of lung function by fast track surgery in patients with radical resection of lung cancer	22
The effects of nutritional support on cellular immunity of the patient with multiple myeloma undergoing chemotherapy	21
Left atrial appendage closure: a new strategy for cardioembolic events despite oral anticoagulation	21
The intergated approach to the management of arterial hypertension: The Campania Salute Network	18
Metabolically healthy obesity and chronic kidney disease risk: exploring the dynamics	16
An update on the pathophysiology of acute and recurrent pericarditis	15
The operation of carotid endarterectomy: is it an effective method of treatment of arterial hypertension?	15
The effect and mechanism of CDK11 in promoting breast cancer cell proliferation, migration, and doxorubicin resistance by regulating EGFR	15
MiR-379 relieves myocardial injury after acute myocardial infarction by regulating tumor necrosis factor-α-induced protein 8	15
Helicobacter pylori eradication in elderly patients: can we assume that a bismuth-based therapy is effective as in young people?	14
Comparative study of efficacy of breast-conserving surgery and modified radical mastectomy in treating early breast cancer	14
Effect of high-quality nursing intervention in obstetrics and gynecology nursing	14
Application effect of humanized nursing in the treatment of ovarian cancer with paclitaxel and cisplatin	12
Ethical issues surrounding appropriate care for older persons in the Intensive Care Unit	12
Analysis of incidence and influencing factors of hyperuricemia in elderly patients with hypertension	12
Correlations of inflammation, oxidative stress and prognosis with expression of lncRNA H19 in rats with sepsis-evoked lung injury	11
Chronic venous insufficiency and microangiopathy: supplementation with Pycnogenol® reduces the progression of venous disease in women	11
Analysis of the clinical effect of posterior focus debridement and interbody bone grafting in the treatment of spinal tuberculosis	11
MiR-21 accelerates tibial fracture healing in rats by regulating TGF-β1/Smad signaling pathway	11

Newer therapeutic approaches towards the management of diabetes mellitus: an update	10
The art of ART: an editorial	10
The vaccine journey for COVID-19: a comprehensive systematic review of current clinical trials in humans	10
Poorly differentiated thyroid carcinoma: molecular, clinico-pathological hallmarks and therapeutic perspectives	10
Microbiota treatment: the future target to prevent cardiovascular disease?	10
The URRAH study	9
Correlation between blood glucose changes and sleep quality in type 2 diabetes patients with sleep disorders	9
The evaluation of meticulous and humanized nursing management mode on patient's physiology, psychology and comfort level as well as the incidence of adverse events in operating room	9
Correlation of MRI findings, pathological differentiation with GPC3, CD34, CK19, CK7 expression and prognosis in patients with hepatocellular carcinomas	9
Pharmacologic treatment of acute and recurrent pericarditis: a systematic review and meta-analysis of controlled clinical trials	9
Effect of simvastatin on fracture healing of type 2 diabetic rats	9
LncRNA CASC7 inhibits myocardial apoptosis in myocardial ischemia-reperfusion rats by regulating MiR-21 expression	8
Impact of anabolic androgenic steroids on male sexual and reproductive function: a systematic review	8
Thymic stromal lymphopoietin alleviates fibrosis after myocardial infarction through regulating STAT3	8
Application value of Doppler ultrasound in renal hemodynamic monitoring in patients with septic shock	8
Implantation of one, two or multiple MitraClip™ for transcatheter mitral valve repair: insights from a 1824-patient multicenter study	8
Study of febuxoat and allopurinol placebo in patients with high uric acid excretion and calcium stones	8
A nutrigenetic tool for precision dietary management of non-alcoholic fatty liver disease deeming insulin resistance markers	8
Corrected and republished from: Metabolic associated liver disease	8
Troxerutin attenuates isoproterenol-induced cardiac hypertrophy via the LKB1/AMPK/mTOR pathway	8
Microbiota restoration for recurrent Clostridioides difficile infection	8
Study on the cleaning effect of medical protective positive pressure air supply respirator during COVID-19	8
One-year of pulmonologist-based teleconsultation between hospital and general practitioners: an Italian exploratory investigation	7
Long non-coding RNA MALAT1 promotes cell proliferation, migration and invasion in cervical cancer by targeting miR-625-5p and AKT2	7
The PAMELA research project: a 25-year long journey	7
MiR-29c-3p inhibits proliferation and migration in rat primary cardiac fibroblasts via interacting with STAT3	7
A report on the Gubbio Study thirty-eight years after its inception	7
Rosuvastatin reduces expression of tissue factor through inhibiting RhoA/ROCK pathway to ameliorate atherosclerosis	7
LncRNA CYTOR and MIR4435-2HG in ovarian cancer and its relationship with clinicopathological features	7
The effect and exploration of continuous positive pressure ventilation combined with upper limb robot training on upper limb function in stroke patients with OSAHS	7
Exploring the relationship between the oral microbiota and fasting blood glucose level based on the analysis of NHANES data	7
Analysis of changes in cardiac function parameters before and after surgery in OSAS patients	6
Vitamin D and non-Hodgkin lymphomas, trends from an Italian monocentric study	6
Clinical study of early intervention of brain-derived nerve growth factor on reducing the degree of brain injury in newborns with severe asphyxia	6
Prevalence of airflow obstruction in an apparently healthy population sample: a preliminary Italian study	6
MiR-30d inhibits cardiomyocytes autophagy promoting ferroptosis after myocardial infarction	6
Observation on the effect of modified adhesive retained posterior implant denture on the tissue around the implant	6
Clinical effect of urinary kallindinogenase in the treatment of acute cerebral infarction of different TOAST types	6
Effect and mechanism of mir-574-5p regulating mpegs on drug resistance of pC9/h1993 cells	6
Effect observation and satisfaction analysis of rehabilitation nursing intervention in rheumatoid arthritis nursing	6
Effect of interferon-α-2b and interleukin-2 combined with chemotherapy in metastatic melanoma	6
Application of comprehensive nursing intervention in nursing of patients with bronchial asthma and allergic rhinitis	6
Acute leukemia diagnosis during the COVID-19 pandemic	6
Effect of baicalin combined with adipose stem cells on promoting angiogenesis and improving wound healing in diabetes	6
Preoperative management of medications for psychiatric disorders	6
Arthroscopic treatment for popliteal cysts	6
Exercise for slowing the progression of atherosclerotic process: effects on inflammatory markers	6
A recombinant adenovirus fiber knob protein sensitizes gastric cancer cells to trastuzumab	6
Difficulty encountered in the early radiological diagnosis of atypical pancreatic duct stones compared to the typical type in Chinese patients	5
Correlation analysis between ADRB1 gene polymorphism and eclampsia	5

MiR-21-5p reduces apoptosis and inflammation in rats with spinal cord injury through PI3K/AKT pathway	5
The value of oral contrast-enhanced ultrasonography in the diagnosis of gastric tumors in the elderly	5
Novel insights on lymphoma and lymphomagenesis in primary Sjögren's Syndrome	5
Clinical features and risk factors in patients with acute myocardial infarction in different age groups	5
Meta-analysis of women's reproductive tract infection survey	5
Clinical efficacy analysis of rehabilitation therapy for patients with neurological dysfunction caused by cerebrovascular disease	5
Moving towards core antigen for the management of patients with overt and occult HBV infection	5
CA-074Me inhibits cathepsin-B and alleviates fibrosis after myocardial infarction	5
Effect of N6 adenylate methylation on myocardial hypertrophy through METTL14 regulation	5
Efficacy and safety of long-term warfarin anticoagulation in elderly non-valvular atrial fibrillation patients	4
LncRNA GHET1 promotes osteoblast proliferation and differentiation by inhibiting PTEN	4
Hydrogen sulfide inhibits inflammation and improves chronic renal failure through NF-κB signaling pathway	4
Effectiveness of tocilizumab in hospitalized moderate-to-severe COVID-19 patients: a real-life study	4
LncRNA CCAT2 promotes the proliferation and invasion of renal cell cancer by sponging miR-320a	4
miR-30c inhibited cell migration and invasion via LGI1 in clear cell renal cell carcinoma	4
Effect analysis of recombinant human growth hormone therapy in short stature children	4
Pranoprofen inhibits endoplasmic reticulum stress-mediated apoptosis of chondrocytes	4
Rapid calcification after large area cerebral infarction	4
Recurrent pericarditis: an update on diagnosis and management	4
Therapeutic effects of 595-nm pulsed dye laser on children's nevus flammeus and incidence of adverse reactions	4
Correlation of MMP-2 gene polymorphism with neonatal hypoxic-ischemic encephalopathy	4
The Vobarno Study	4
Correlations of MMP-3 and MMP-9 gene polymorphisms with diabetic retinopathy	4
LncRNA PVT1 participates in the development of oral squamous cell carcinomas through accelerating EMT and serves as a diagnostic biomarker	4
Efficacy analysis of continuous blood purification therapy for patients with severe acute pancreatitis and acute kidney injury	4
Alcohol dehydrogenase 2/aldehyde dehydrogenase 2 genetic polymorphisms in obstructive sleep apnea syndrome	4
Protein kinase TBK1/IKKε inhibitor Amlexanox improves cardiac function after acute myocardial infarction in rats	4
Acquired hemophilia A induced by clopidogrel	4
miR-495 inhibits fibroblast-like synoviocyte proliferation and inflammation in rheumatoid arthritis rats via Wnt signaling pathway	4
Keep on tailoring CMV management in lung transplantation: 24 versus 12-month CMV hyperimmune globulins regimen effects in combined universal prophylaxis	4
MiR-181a reduces radiosensitivity of non-small-cell lung cancer via inhibiting PTEN	4
Paroxysmal nocturnal hemoglobinuria-like phenotype and thrombotic risk in several clinical disorders	4
Effect of cognitive dysfunction on the outcome of coronary artery bypass grafting in patients	4
lncRNA-Gm4419 alleviates renal damage in rats with diabetic nephropathy through NF-κB pathway	3
Complete versus culprit-only coronary revascularization in patients with myocardial infarction and multivessel disease undergoing percutaneous coronary intervention: an updated meta-analysis	3
Analysis of the effect of multimedia-assisted psychological nursing in perioperative period of cardiac surgery with cardiopulmonary bypass	3
The HARVEST: looking for optimal management of young people with stage 1 hypertension	3
tudy on the effect of heart-shaped tension-reducing cosmetic suture on reducing the formation of abdominal scar in cesarean section	3
MiR-132 represses sepsis-induced myocardial injury in rats by regulating SIRT1 expression	3
Long-term physical activity modulates adipsin and ANGPTL4 serum levels, a potential link to exercise-induced metabolic changes	3
The expression of Nrf2-ARE signaling pathway combined with plasma platelet activating factor in elderly patients with respiratory failure and its correlation with lung function	3
ICSI for non-male factor infertility: time to reappraise IVF?	3
Study on the efficacy and safety of fallopian tube interventional recanalization in the treatment of tubal obstructive infertility	3
Effects of edaravone on cerebral ischemia-reperfusion in mice through the TLR4/NF-κB/TNF-α pathway	3
Protective effect of anthocyanin B2 on traumatic optic nerve injury in rats	3
HMGA1 promotes the development of esophageal squamous cell carcinoma by mediating miR-671-5p/lncRNA DLEU1	3
Tricuspid regurgitation: a contemporary review	3
The expression of CT quantitative indicators in patients with chronic obstructive pulmonary disease and their correlation with lung function	3
A novel algorithm for the computation of the diastolic pressure ratio in the invasive assessment of the functional significance of coronary artery disease	3
ChatGPT: unlocking the potential of Artifical Intelligence in COVID-19 monitoring and prediction	3
Efficacy of the combination Pycnogenol® and Centellicum® on preventing the progression of atherosclerotic plaques: a morphological study	3
MicroRNA-326 inhibits cell proliferation and invasion in esophageal squamous cell carcinoma through targeting LIM and SH3 protein 1	3
Effect of repetitive transcranial magnetic stimulation on quality of life and cortical excitability in patients with cerebral infarction	3
The Progetto Ipertensione Umbria Monitoraggio Ambulatoriale (PIUMA) Study	3
Experience summary of a COVID-19 designated community hospital and its operation model	3
Comparative observation on the effect of laparoscopic sleeve gastrectomy and routine weight loss in the treatment of obesity and the improvement of blood pressure	3
Metabolic syndrome and andrological diseases	3
Dizziness, psychological disorders and cognitive decline	3
Clinical decisions for appropriate management of patients with atrial fibrillation	3
Thromboembolism in COVID-19: the unsolved problem	3
Restless legs syndrome: prevention with Pycnogenol® and improvement of the venoarteriolar response	3
Diet as a possible influencing factor in thyroid cancer incidence: the point of view of the nutritionist	3
Long non-coding RNA LINC00299 knockdown inhibits ox-LDL-induced T/G HA-VSMC injury by regulating miR-135a-5p/XBP1 axis in atherosclerosis	3
Wernicke encephalopathy, myasthenia gravis, or both?	3
Analysis of the predictive value of real-time shear wave elastography in detecting the elastic hardness of liver and spleen in patients with portal hypertension of hepatitis B cirrhosis	3
Analysis of diagnostic efficacy and curative effect assessment value of computed tomography and magnetic resonance imaging for atherosclerosis	3