OOIR: Observatory of International Research

Papers

(The H4-Index of New England Journal of Medicine is 232. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Screening for Prostate Cancer	4448
SENIOR-RITA — Is It All about Angiography?	2885
Cerebral Embolic Protection during TAVI	2362
Audio Interview: Dissecting the Host Response to SARS-CoV-2	2313
Listening and Responding to Community Voices — The Community Wellness HUB	2283
Automated Insulin Pump in Type 2 Diabetes	2257
Haloperidol for the Treatment of Delirium in ICU Patients	2112
How to Save a Life	1814
Monoclonal Antibodies in the Pathogenesis of Heparin-Induced Thrombocytopenia	1532
Minocycline-Induced Hyperpigmentation	1452
Left Atrial Appendage Closure — Another Overused Method in Cardiology?	1391
More Options for Gene Editing in Hemoglobinopathies	1356
Use of Wastewater for Mpox Outbreak Surveillance in California	1286
Bismuth Subsalicylate Poisoning	1004
Permethrin-Treated Baby Wraps for the Prevention of Malaria	991
Selective Digestive Decontamination — Finding the Way Forward	977
Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure	953
Debating Race and the Diagnosis of Anemia — How Medicine Moved Away from Race-Based Standards	926
Case 18-2025: A 63-Year-Old Woman with Dyspnea on Exertion	913
Turning CMS into a Health Technology Assessment Organization	891
A Modern Therapy for an Ancient Disease	888
Hiding in Plain Sight	871
Nonketotic Hyperglycemic Hemichorea	850
A Trial of Trimethoprim–Sulfamethoxazole in Pregnancy to Improve Birth Outcomes	846
Empagliflozin in Heart Failure with a Preserved Ejection Fraction	842

Rethinking Shadowing for Aspiring Physicians	828
Redefining Lung Cancer Therapy — A Long-Awaited Shift in Strategy	797
Ten Years of Incidental, Secondary, and Actionable Findings	792
Paget’s Disease of the Breast	788
A Swell Diagnosis	785
Postacute Sequelae of SARS-CoV-2 Infection in Several Eras	776
Race-Based Diagnosis, Part 1 — ITT Episode 33	763
Investigating Injustices in the Journal ’s History, Part 2	758
Hemotympanum with a Basilar Skull Fracture	752
Secondary Hypertrophic Osteoarthropathy	745
Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors	716
Psychosocial Functioning in Transgender Youth after 2 Years of Hormones	712
Testing for Arginine Vasopressin Deficiency	704
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort	687
The Muffin Question	682
Bilothorax	680
Audio Interview: Assessing Bivalent Vaccines against Covid-19	664
Nationwide, Couple-Based Genetic Carrier Screening	663
Poet as Patient	662
Navigating and Communicating about Serious Illness and End of Life	659
Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism	658
Adrenal Involvement in Disseminated Histoplasmosis	646
Multicentric Reticulohistiocytosis	635
Black Dot Tinea Capitis	633
Timing Is Everything — Evidence for When to Perform Complete Revascularization in STEMI	633
Convalescent Rash of Dengue	628
Bumps in the Road	624
Foreign-Body Aspiration in a Child	620
Prolonging Cellular Life after Hypoxic Death	618
Middle Meningeal Artery Embolization for Subdural Hematoma	617
Cholelithiasis, Cholecystitis, and Choledocholithiasis	605
Breaking the Sacred Promise	596
Gazing into a Crystal Ball	596
Designing Cures 2.0 — From Corridors to Cornerstones	593
Pistachio Ice Cream	590
Catching Up on REMs	589
Exclusion of Elective Care from Hospital Financial Assistance Policies — Arresting a Troubling Development	581
Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial	581
Overcoming Resistance — Omission of Radiotherapy for Low-Risk Breast Cancer	579
Tenecteplase for Stroke — Opening the Window?	577
Perioperative Durvalumab in Bladder Cancer	568
Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs	568
Malnutrition in Adults	567
A Case of Cervical Ectopic Pregnancy after the Dobbs Decision	567
Smallpox at the Siege of Boston, November 1775–March 1776	538
Optical Coherence Tomography and Eye Care	527
From the Eyeball Test to the Algorithm — Quality of Life, Disability Status, and Clinical Decision Making in Surgery	521
Preparing for the Next Pandemic — Expanding and Coordinating Global Regulatory Capacity	511
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid	510
Ménétrier’s Disease	502

Genetic Variation in Clinical Cohorts	494
Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam	492
Targeting CSF1R in Chronic GVHD — Lessons in Translation	488
Asciminib in Newly Diagnosed Chronic Myeloid Leukemia	485
Modifiable Risk Factors and Cardiovascular Outcomes	483
Spontaneous Intracranial Hypotension	479
Early Active Mobilization during Mechanical Ventilation in the ICU	476
Virotherapy for Brain Tumors — Defining the Path to Success	474
Gantenerumab in Early Alzheimer’s Disease	467
Mucosal IgA against SARS-CoV-2 Omicron Infection	463
U.S. Law and Discrimination in Health Care	459
Childhood Risk Factors and Adult Cardiovascular Events	441
Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections	440
Hypothermia or Machine Perfusion in Kidney Donors	436
Threatening the Future of Global Health — NIH Policy Changes on International Research Collaborations	436
Nutritional Support for Moderate-to-Late–Preterm Infants — A Randomized Trial	435
Number Needed to Treat	431
BCMA-Targeted T-Cell Engager for Autoimmune Hemolytic Anemia after CD19 CAR T-Cell Therapy	431
Sacituzumab Govitecan in Untreated, Advanced Triple-Negative Breast Cancer	430
Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype	428
Transformative Research in Cystic Fibrosis	428
Evidence-Based Work Design — Bridging the Divide	421
Teclistamab plus Daratumumab in Relapsed or Refractory Multiple Myeloma	418
HFpEF Explained — Prevalence, New Advances, and How to Diagnose	417
Reteplase versus Alteplase for Acute Ischemic Stroke	414
Zilebesiran for Hypertension	411
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer	410
Monoclonal Antibodies for Malaria	409
Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD	409
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes	409
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts	407
Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B	406
Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk	405
Navigating and Communicating about Serious Illness and End of Life	402
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer	400
Measurable Residual Disease–Guided Therapy for Chronic Lymphocytic Leukemia	398
First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia	395
Bronchiectasis — A Clinical Review	394
A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA	390
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction	387
Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma	387
Understanding How Aspirin Prevents Metastasis	384
Periprosthetic Joint Infection	380
A Tale of Two Diseases	379
Hospital Problems	378
Criminalizing Homelessness — The Grants Pass, Oregon, Supreme Court Case	377
NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction	375
Autoantibodies Targeting Nephrin in Podocytopathies	372
Transforming Management of Opioid Use Disorder with Universal Treatment	368
The Death of an Unlikable Man	367
The Increasing Incidence of Early-Onset Colorectal Cancer	366
Water-Based and Waterless Surgical Scrub Techniques	365
Ondansetron after ED Visits in Children with Gastroenteritis	362
Guidance on Energy and Macronutrients across the Life Span	360
Early Outpatient Treatment for Covid-19 with Convalescent Plasma	357
Immune Checkpoint Inhibitors — The Need for Innovation	357
Academic Freedom in America — In Support of Institutional Voices	357
Neurovascular Complications of Iatrogenic Fusarium solani Meningitis	356
A Preview of the Dangerous Future of Abortion Bans — Texas Senate Bill 8	356
Targeting Lipoprotein(a) — the Next Frontier in Cardiovascular Disease	355
“Putting America First” — Undermining Health for Populations at Home and Abroad	355
Cholesterol Pericarditis	354
Case 38-2024: A 22-Year-Old Woman with Headache, Fever, and Respiratory Failure	352
Crinecerfont in Adult Congenital Adrenal Hyperplasia	351
Case 5-2023: A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias	349
Personality Disorders	349
HIV Prevention and the 340B Drug Pricing Program	348
Audio Interview: Rolling Out New Covid-19 Vaccines	348
Japanese Spotted Fever	344
Medication for Gastroesophageal Reflux Disease in Infants	341
Broken Both Ways	340
Convalescent Plasma for Covid-19–Induced ARDS	330
What We Don’t Know about School Shooter Drills	329
Case 21-2023: A 61-Year-Old Man with Eyelid Swelling	327
Felzartamab in Antibody-Mediated Rejection	326
Intravenous Amino Acids and Kidney Protection	326
Routine Removal of Inferior Vena Cava Filters	325
Diagnostic Aspirations	322
Case 26-2022: A 48-Year-Old Woman with Cystic Lung Disease	322
Guilty	320

End of a Declared Public Health Emergency — Implications for U.S. Emergency Use Authorizations	320
Audio Interview: Ending the Covid-19 Public Health Emergency	320
PD-1 and PD-L1 Blockade plus Chemotherapy in Endometrial Cancer	319
Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes	319
Expect With Me — Group Prenatal Care to Reduce Disparities	318
Laryngeal Candidiasis	309
In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6	305
Postherpetic Abdominal Pseudohernia	304
Can AI Solve Primary Care?	303
Dengue Suppression by Male Wolbachia-Infected Mosquitoes	301
Pegylated Interferon Lambda for Covid-19	299
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation	298
Mycoplasma-Induced Rash and Mucositis	298
Integration of Tobacco-Cessation Interventions into Tuberculosis and HIV Care	294
Genital Herpes Zoster	294
Making Long-Term Oxygen Therapy Less Burdensome	294
Disappearing Data at the U.S. Federal Government	293
Transfusion Strategy in Myocardial Infarction and Anemia	293
Occupational Health and Safety on the Chopping Block — What’s at Stake?	292
Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas	292
Trials for Managing Acute Pain — A Clinically Meaningful Small Effect Size?	292
Medication-Associated Diethylene Glycol Mass Poisoning — A Preventable Cause of Illness and Death	291
Closing the Evidence Gap for Drugs in Children — Measures to Strengthen the Pediatric Research Equity Act	290
Cardiac Implantable Electronic Devices	290
Moving the Needle on Alzheimer’s Disease with an Anti-Oligomer Antibody	289
Invasive Strategy for Older Patients with MI	288
Amivantamab–Lazertinib in EGFR -Mutated Advanced NSCLC	288
Covid-19 Surveillance Testing in Nursing Homes	287
Vocal-Cord Polyp Causing Airway Obstruction	284
Behçet’s Syndrome	283
Elective Cesarean Section for Maternal Preference	281
Focused Cardiac Ultrasonography for Right Ventricular Size and Systolic Function	280
Fulminant Viral Myocarditis Associated with Thogotovirus	280
Increasing Firearm-Related Deaths among U.S. Black Rural Youths	275
Necrolytic Migratory Erythema	274
Trends in Youth-Onset Type 2 Diabetes, 2013–2024	274
Leveraging School Systems as Data Partners to Advance Health Equity	274
Immunogenicity and Safety of vYF, a Yellow Fever Vaccine — A Phase 2 Trial	272
Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial	271
Emodepside for Trichuris trichiura and Hookworm Infection	268
Compared with What? Measuring AI against the Health Care We Have	267
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes	267
Tuberculous Meningitis — New Approaches Needed	266
Functional Dyspepsia	264
Chylothorax	263
FINEARTS-HF — The Latest Masterpiece for MRAs in Heart Failure	262
Small Step or Giant Leap? Expanding the Acute Stroke Thrombolysis Window to 24 Hours	261
Gastric Syphilis	261
Public Health’s Role in a Post- Dobbs World — The New York City Abortion Access Hub	260
Gustatory Hyperhidrosis after Parotid Surgery	260
Pretomanid in the Treatment of Patients with Tuberculosis in the United States	260
Audio Interview: Ending the Covid-19 Emergency	259
The Risks of Normalizing Parental Vaccine Hesitancy	259
Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases	256
Association between Covid-19 Vaccination and Influenza Vaccination Rates	255
Atrial Fibrillation — What Is It and How Is It Treated?	253
SGLT2 Inhibitors and False Positive Toxicology Tests	252
A Dual-Chamber Leadless Pacemaker	251
Monkeypox	250
Ultraprocessed Food on an Ultrafast Track	250
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension	249
Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis	247
Helicobacter pylori , Homologous-Recombination Genes, and Gastric Cancer	245
Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation	242
Chronic Traumatic Encephalopathy in the Brains of Military Personnel	242
Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer	242
Phase 1–2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B	242
Safety and Efficacy of Denosumab for Fibrous Dysplasia of Bone	241
Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial	241
Advanced HIV as a Neglected Disease	240
Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction	239
Artificial Intelligence in Medicine	238
New Perioperative Strategy in Gastric Cancer	238
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity	236
A Physician Attack on the FDA — Will the Supreme Court Reduce Access to Mifepristone?	236
Bivalent Covid-19 Vaccines — A Cautionary Tale	235
Autoantibodies Targeting Nephrin in Podocytopathies	235
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation	232
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy	232
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis	232
Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction	232