Naunyn-Schmiedebergs Archives of Pharmacology

Article	Citations
Pharmacokinetics of chromium-enriched yeast in rats following oral administration	153
Azilsartan as a preventive agent against cyclophosphamide-induced testicular injury in male rats	140
Inhibitory effects of N-methyl-D-aspartate (NMDA) and α1-adrenergic receptor antagonist ifenprodil on human Kv1.5 channel	134
Long noncoding RNA MATN1-AS1 contributes to oxaliplatin resistance of gastric cancer cells through miR-518b/ZNF281 axis	88
Revealing the active ingredients and mechanisms of Xiatianwu against hepatocellular carcinoma: a study based on network pharmacology and bioinformatics	82
PDE5 inhibitors and gastric mucosa: implications for the management of peptic ulcer disease	66
Pirfenidone mitigates demyelination and electrophysiological alterations in multiple sclerosis: Targeting NF-κB, sirt1, and neurotrophic genes	66
Anti-adipogenesis and anti-obesity potential of alliin mediated by modulating glycolipid metabolism via activating PPARγ signaling	61
Inhibition of uterine contractility by guanine-based purines in non-pregnant rats	58
Research dynamics and drug treatment of renal fibrosis from a mitochondrial perspective: a historical text data analysis based on bibliometrics	57
Therapeutic effect of bismuth subsalicylate in a propionic acid–induced autism model	54
The novel piperine derivative MHJ-LN inhibits breast cancer by inducing apoptosis via p53 activation	52
Raddeanin A promotes autophagy-induced apoptosis by inactivating PI3K/AKT/mTOR pathway in lung adenocarcinoma cells	47
Insight into the mechanism of action of ORG27569 at the cannabinoid type one receptor utilising a unified mathematical model	46
Sequential administration of febuxostat and vitamin E protects against testicular ischemia/reperfusion injury via inhibition of sperm DNA damage in Wistar rats	43
Synergistic effects of sequential treatment with doxorubicin and zoledronic acid on anticancer effects in estrogen receptor-negative breast cancer cells	43
The neurotoxic effects of lead acetate and the abrogating actions of 6-gingerol-rich extract of ginger via modulation of antioxidant defence system, pro-inflammatory markers, and apoptotic cascade	39
Unraveling the rationale and conducting a comprehensive assessment of AdipoRon (adiponectin receptor agonist) as a candidate drug for diabetic nephropathy and cardiomyopathy prevention and interventio	39
Senkyunolide I prevent chondrocytes from oxidative stress through Nrf2/HO-1 signaling pathway	38
Assessment of pharmacodynamic interactions of two-drug combinations of five selected cytostatics in an in vitro model of human melanoma: an isobolographic analysis	38
EGFR-targeted tyrosine kinase inhibitors: advancements in cancer therapy	37
Efficacy and safety of different doses of ligelizumab in patients with chronic spontaneous urticaria: a systematic review and meta-analysis of randomized controlled trials with GRADE evaluation	37
Pregnancy outcomes following oral brivudine exposure: two case studies with long-term follow-up	36
Pharmacokinetics and bioequivalence evaluation of two oral formulations of topiramate tablets in healthy Chinese male volunteers under fasting and fed conditions	36
Gymnemagenin-3-O-glucuronide mitigates lipopolysaccharide-induced acute lung inflammation/injury by regulating the NF-κB/MAPK signalling	35

Local administration of curcumin-loaded nanoparticles enhances periodontal repair in vivo	34
[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice	33
Application of GBD 2021 and multiple omics to reveal the association and potential mechanism between glycated hemoglobin and intervertebral disc degeneration	33
Long COVID could become a widespread post-pandemic disease? A debate on the organs most affected	33
Schmiedeberg Medal for Thomas Wieland: an artist of G-protein signaling	32
Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in gastrointestinal cancers	31
Ischemia does not provoke the full immune training repertoire in human cardiac fibroblasts	30
Transglutaminase 3 suppresses proliferation and cisplatin resistance of cervical cancer cells by inactivation of the PI3K/AKT pathway	30
The functions of hydrogen sulfide on the urogenital system of both males and females: from inception to the present	30
Evaluation of the protective effect of losartan in acetaminophen-induced liver and kidney damage in mice	30
Electric field-directed migration of mesenchymal stem cells enhances their therapeutic potential on cisplatin-induced acute nephrotoxicity in rats	30
Potential applications of antofine and its synthetic derivatives in cancer therapy: structural and molecular insights	30
Correction to: Exploring the bioactive ingredients of three traditional Chinese medicine formulas against age-related hearing loss through network pharmacology and experimental validation	30
Real-world safety profile of opicapone: a comprehensive pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database	29
Development and evaluation of methotrexate-loaded nanoemulsion formulation for topical treatment of psoriasis	29
RETRACTED ARTICLE: Barbaloin: an amazing chemical from the ‘wonder plant’ with multidimensional pharmacological attributes	29
Presentation of the obsolete drug reserpine in three German-language pharmacology textbooks	29
Retraction Note: Barbaloin: an amazing chemical from the ‘wonder plant’ with multidimensional pharmacological attributes	29
Regulation of tight junction proteins and cell death by peroxisome proliferator-activated receptor γ agonist in brainstem of hypertensive rats	28
LncRNA TRPM2-AS promotes cell proliferation, migration, and invasion by regulating the miR-195-5p/COP1 axis in bladder cancer	28
Retraction Note: CTLA4-Ig alleviates the allogeneic immune responses against insulin-producing cells in a murine model of cell transplantation	28
Pathological role of RAGE underlying progression of various diseases: its potential as biomarker and therapeutic target	28
Approaches based on natural products and miRNAs in pituitary adenomas: unveiling therapeutic intervention	28
Biological potential and therapeutic effectiveness with diverse signaling pathways of phyto-product chicoric acid: a comprehensive review with computational evidence	27
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis	27
Unwinding circular RNA’s role in inflammatory pulmonary diseases	27
The publish or perish, publish and perish, publish then perish, and now retract and perish cultures in academia	27
Repurposing fluoroquinolones as cancer chemosensitizers: a way to overcome cancer therapeutic bottleneck	27
Inhibition of mitochondrial respiration by general anesthetic drugs	27
Ligand-human serum albumin analysis: the near-UV CD and UV-Vis spectroscopic studies	27
Small-molecule LF3 alleviates angiotensin II-induced cardiac dysfunction via attenuating cardiac fibrosis	27
Multifunctional magnetic nanocapsules for dual delivery of siRNA and chemotherapy to MCF-7 cells (Breast cancer cells)	27
Investigating the efficacy of gliclazide encapsulated hydrogel in the preclinical mice model for atopic dermatitis	27
Examining the contribution of Notch signaling to lung disease development	26
Retraction Note: Chronic stress-mediated dysregulations in inflammatory, immune and oxidative circuitry impairs the therapeutic response of methotrexate in experimental autoimmune disease models	26
Ethyl acetylsalicylate (E-ASA) protects against myocardial ischemia–reperfusion injury	26
Chrysophanol ameliorates ferroptosis in acute kidney injury by promoting SIRT3-mediated NRF2 deacetylation	26
Rosmarinic acid, the active component of Rubi Fructus, induces apoptosis of SGC-7901 and HepG2 cells through mitochondrial pathway and exerts anti-tumor effect	26
A review on hypervirulent and multidrug-resistant Klebsiella pneumoniae: An emerging threat to human health	26
Mechanistic and AI-assisted evaluation of paclitaxel-loaded HSPC liposomes for targeted breast cancer therapy	25
Ginsenoside Rh2 inhibits non-small-cell lung cancer malignant progression through targeting AURKA	25
Pharmacovigilance insights into drug-induced hypercalcemia: evidence from the U.S. FDA Adverse Event Reporting System (FAERS) database	25
Perfluorooctanoic acid exposure and its neurodegenerative consequences in C57BL6/J mice	25
Erbium oxide nanoparticles induce potent cell death, genomic instability and ROS-mitochondrial dysfunction-mediated apoptosis in U937 lymphoma cells	25
The gut–brain axis: role of gut microbiota in neurological disease pathogenesis and pharmacotherapeutics	25
Diosgenin-loaded niosomes ameliorate cadmium-induced neurotoxicity and endocrine disruption in female rats through modulation of oxidative stress, apoptosis, and inflammatory markers	25
Retraction Note: Thymoquinone dose‑dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fib	24
Post-marketing safety evaluation and objective benefit-risk assessment of sublingual immunotherapy tablets in allergic rhinitis	24
Costunolide attenuates LPS-induced inflammation and lung injury through inhibiting IKK/NF-κB signaling	24
Pathophysiology, conventional treatments, and evidence-based herbal remedies of hair loss with a systematic review of controlled clinical trials	24

Integrated ADME, metabolomics, and multi-target docking of Novel methoxy- and thiophene-substituted benzodioxane hydrazones	24
Friedelin: A natural compound exhibited potent antibacterial, anti-inflammatory, and wound healing properties against MRSA-infected wounds	24
Saussurea costus (Falc.) Lipsch.: a comprehensive review of its pharmacology, phytochemicals, ethnobotanical uses, and therapeutic potential	24
Modulation of Lingo-1 and NMDA receptor expression by memantine and vitamin D3 co-therapy attenuates motor and non-motor symptoms in essential tremor	24
Effects of astragaloside IV on the proliferation and osteogenic differentiation of human jaw bone marrow mesenchymal stem cells in vitro	24
The role of TLR4/NF-kB signaling axis in pneumonia: from molecular mechanisms to regulation by phytochemicals	23
THE effect of P2X7 receptor activation on functional responses of human left internal mammary artery	23
Research focus and thematic trends of transient receptor potential vanilloid member 1 research: a bibliometric analysis of the global publications (1990–2023)	23
Gentiopicroside inhibits retinoblastoma cell proliferation, invasion, and tumorigenesis in nude mice by suppressing the PI3K/AKT pathway	23
Clinical trials on curcumin in relation to its bioavailability and effect on malignant diseases: critical analysis	23
Fraxin alleviates oral lichen planus by suppressing OCT3-mediated activation of FGF2/NF-κB pathway	23
Target prediction and potential application of dihydroartemisinin on hepatocarcinoma treatment	23
Dihydroxyflavones as potential therapeutic agents against inflammation and renal injury via p38 MAP kinase inhibition: an in silico and experimental study	23
Sodium diethyldithiocarbamate trihydrate: an effective and selective compound for hematological malignancies	23
Therapeutic potential of Bergenin in the management of neurological-based diseases and disorders	23
Label-free cell phenotypic profiling of sphingosine-1-phosphate receptor 1 and discovery of its agonist from natural products	23
Verification of nucleotide sequence reagent identities in original publications in high impact factor cancer research journals	22
Effect of alpha-lipoic acid and caffeine-loaded chitosan nanoparticles on obesity and its complications in liver and kidney in rats	22
Radiologic and histopathologic effects of favipiravir and hydroxychloroquine on fracture healing in rats	22
Efficacy of oltipraz in preventing acetaminophen-induced liver injury in mice	22
Cantharidin and sodium fluoride attenuate the negative inotropic effects of carbachol in the isolated human atrium	22
Efficacy of umbelliferone-loaded nanostructured lipid carrier in the management of bleomycin-induced idiopathic pulmonary fibrosis: experimental and network pharmacology insight	21
Oroxylin A exerts antiproliferative effects through downregulation of E6 and E7 oncogenes in cervical cancer HeLa cells	21
Efficacy and safety of vunakizumab between super responders and non-super responders of patients with moderate-to-severe plaque psoriasis: a post-hoc exploratory analysis of a phase III trial	21
Lifecycle regulation of narrow therapeutic index drugs: Chinese practices, international benchmarks, and optimization pathways	21
Transcriptomic and multi-layer variant analysis identifies STAT3 and HIF1A as central regulators of regulated cell death pathways in lung squamous cell carcinoma	21
Obituary: Arnold Hasselblatt (1929 - 2024)	21
Astragaloside IV-PESV facilitates pyroptosis by enhancing palmitoylation of GSDMD protein mediated by ZDHHC1	20
Unlocking the biological potential of methyl antcinate A: a new frontier in cancer and inflammation application	20
A quinoline derivative exerts antineoplastic efficacy against solid tumour by inducing apoptosis and anti-angiogenesis both in vitro and in vivo	20
Apoptotic and antimetastatic effect of cucurbitacins in cancer: recent trends and advancement	20
Retraction Note: Chlorantraniliprole (Coragen® 20% SC) exposure induced reproductive toxicity mediated by oxidative stress, apoptosis, and sperm quality deficient in male Wistar rats	20
Can nonsteroidal anti-inflammatory drugs (NSAIDs) be repurposed for fungal infection?	20
Safety, tolerability, pharmacokinetics, and pharmacodynamics of a novel kappa opioid receptor agonist ZYKR1: a randomized double-blind placebo-control phase 1 study in healthy adult human participants	20
Albumin nanoparticles-mediated doxorubicin delivery enhances the anti-tumor efficiency in ovarian cancer cells through controlled release	20
Radioprotective effects of α2-adrenergic receptor agonist dexmedetomidine on X-ray irradiation-induced pancreatic islet cell damage	20
Exploring mechanisms of britannin against colorectal cancer based on experimentally validated network pharmacology	20
Tankyrase: a promising therapeutic target with pleiotropic action	20
Molecular mechanisms underlying methotrexate-induced intestinal injury and protective strategies	19
A bibliometric and critical trend analysis of the anti-cancer potential of Withania somnifera during 2000–2024	19
Network pharmacology analysis of the Huangqi-Gancao herb pair reveals quercetin as a therapeutics for allergic rhinitis via the RELA-regulated IFNG/IRF1 axis response	19
Protective effect of aromadendrin against monoiodoacetate-induced osteoarthritis in rats via modulation of TLR4/MyD88/NF-κB, HO-1/Nrf2, and Bcl-2/Caspase-3 signaling pathways	19
Sexual dysfunction in dichlorvos-exposed male Wistar rat is ameliorated by curcumin and associated with the upregulation of testosterone	19
Resveratrol-mediated disruption of the CD73–adenosine–A2AR/A2BR axis induces antitumor activity in colon cancer cells	19
Exploring the therapeutic potential of natural products in modulating miRNA networks in prostate cancer	19
Regulatory mechanisms of Gentiopicroside on human diseases: a brief review	19
PI3 K/AKT/mTOR pathway and its role in breast cancer stem cells	19
Innovating alopecia treatment: nanostructured lipid carriers as advanced delivery platforms	19
Toxicological and anti-inflammatory activities of doxorubicin loaded onto pH-sensitive poly(β-amino ester) modified mesoporous silica nanoparticles in mice	19
Chemopreventive effects of chitosan nanogel with thiocolchicoside and lauric acid in chemically induced oral carcinogenesis, in a rodent model	19
Association of resveratrol with the suppression of TNF-α/NF-kB/iNOS/HIF-1α axis-mediated fibrosis and systemic hypertension in thioacetamide-induced liver injury	19
Paeonol alleviates ox-LDL-induced endothelial cell injury by targeting the heme oxygenase-1/phosphoinositide 3-kinase/protein kinase B pathway	18
Topical oleic acid reduces nociception and inflammation in a UVB radiation-induced sunburn model in mice	18
The effects of low-dose X-ray pre-irradiation followed by 4-hydroxybenzoic acid and vanillic acid on P-glycoprotein-mediated efflux pirarubicin in multidrug-resistant K562/Dox cells	18
Studies on the mechanism of local and extra-intestinal tissue manifestations in AOM-DSS-induced carcinogenesis in BALB/c mice: role of PARP-1, NLRP3, and autophagy	18
Correction to: Resveratrol inhibits the expression of RYR2 and is a potential treatment for pancreatic cancer	18
Morin: a promising hepatoprotective agent against drug and chemical-induced liver injury	18
Exercise training and vascular heterogeneity in db/db mice: evidence for regional- and duration-dependent effects	18
Synthesizing network pharmacology, bioinformatics, and in vitro experimental verification to screen candidate targets of Salidroside for mitigating Alzheimer’s disease	18
Fritillaria steroidal alkaloids and their multi-target therapeutic mechanisms: insights from network pharmacology	18
Correction: Therapeutic potential of Lawsonia inermis Linn: a comprehensive overview	18
Sodium orthovanadate protects against ulcerative colitis and associated liver damage in mice: insights into modulations of Nrf2/Keap1 and NF-κB pathways	18
Decoding the tumor immune landscape: emerging TIL subsets as prognostic biomarkers and therapeutic targets	18
Development of a 5-HT7 receptor antibody for the rat: the good, the bad, and the ugly	18
AMPA receptor modulation through sequential treatment with perampanel and aniracetam mitigates post-stroke damage in experimental model of ischemic stroke	18
Sotrovimab in the treatment of coronavirus disease-2019 (COVID-19): a systematic review and meta-analysis of randomized clinical trials	18
9th German Pharm-Tox Summit 2024	18
Association of stroke and mortality among patients receiving heart transplantation—a nationwide study	17
Synthesis and antimicrobial evaluation of a new hybrid bis-cyanoacrylamide-based-piperazine containing sulphamethoxazole moiety against rheumatoid arthritis-associated pathogens	17
USP14 increases the sensitivity of retinoblastoma to cisplatin by mediating the ferroptosis	17
Retraction Note: Inhibition of NF-κB signaling and HSP70/HSP90 proteins by newly synthesized hydrazide derivatives in arthritis model	17
Metformin and vitamin D combination therapy ameliorates type 2 diabetes mellitus-induced renal injury in male Wistar rats	17
CAR T cell therapy efficacy and safety in SLE: a systematic review and pooled analysis of 47 patients across 10 studies	17
Drug-associated deep vein thrombosis: a disproportionality analysis of the FDA adverse event reporting system (FAERS) database	17
Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series	17
Toxicity study of silica nanoparticles following 94-day repeated oral administration in Sprague Dawley rats	17
A new opportunity for N-acetylcysteine. An outline of its classic antioxidant effects and its pharmacological potential as an epigenetic modulator in liver diseases treatment	17
Immunologic cell deaths: involvement in the pathogenesis and intervention therapy of periodontitis	17
A randomized, open-label, three-period, cross-over, single intravenous or intramuscular dose, pharmacokinetics and bioequivalence study of vitamin K1 in healthy adults	17
RETRACTED ARTICLE: Ameliorative effect of two structurally divergent hydrazide derivatives against DSS-induced colitis by targeting Nrf2 and NF-κB signaling in mice	17

Investigation of circulating miR-182-3p, miR -382-3p and miR -93, miR -142-3p involved in tamoxifen resistance and sensitivity in luminal-subtype breast cancer patients: a case–control study	17
Oleuropein- and hydroxytyrosol-loaded nanoparticles: a novel strategy against glioblastoma aggressiveness	17
Arbitrariness of bibliometric parameters: a case study on leading scientists in the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT)	17
Trans-sodium crocetinate attenuates acute kidney injury induced by rhabdomyolysis in rats: focusing on PI3K/AKT, apoptosis, and autophagy pathways	17
Anti-diabetic drug pioglitazone reduces Islet amyloid aggregation overload in the Drosophila neuronal cells	17
Empagliflozin demonstrates cytotoxicity and synergy with tamoxifen in ER-positive breast cancer cells: anti-proliferative and anti-survival effects	17
Research advances in polyphenols from Chinese herbal medicine for the prevention and treatment of chronic obstructive pulmonary disease: a review	17
Environmental PET-microplastic exposure and risk of non-alcoholic fatty liver disease: An integrated computational toxicology and multi-omics study	17
Reflections on the 150th anniversary of Naunyn–Schmiedeberg’s Archives of Pharmacology: past, challenges, and future	17
Identifying potential therapeutic targets in periodontitis: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization	17
Ursolic acid acetate and iso-mukaadial acetate bind to Plasmodium falciparum Hsp90, abrogating its chaperone function in vitro	17
Effect of solid lipid nanoparticles loaded with valproate and metformin on pentylenetetrazole-induced epilepsy in rats	17
Distribution of acquired carbapenemase genes among uropathogenic Escherichia coli	16
The beneficial effects of empagliflozin-metformin combination on cardiovascular risk factors in type 2 diabetes mellitus patients	16
Network pharmacology-based strategy to reveal the mechanism of pinocembrin against ovarian cancer	16
An investigation on the cardioprotective potential of lichen compound protocetraric acid by H2O2-induced toxicity in H9c2 rat heart cells through in vitro and in silico analysis	16
CaMKII phosphorylation promotes renal fibrosis in cisplatin induced chronic kidney disease via Smad 2/3 activation	16
Correction: Ethopharmacological evaluation of antidepressant-like effect of serotonergic psychedelics in C57BL/6J male mice	16
Correction: The synergistic effect of resveratrol and curcumin on oncogenic lncRNA MAPT-IT1 and ferroptosis-related genes in breast cancer	16
Comprehensive big data analysis reveals SLC10A3 as a potential biomarker in head and neck cancer	16
Adverse drug reactions to chloroquine/hydroxychloroquine in combination with azithromycin in COVID-19 in-patients: data from intensive pharmacovigilance in Morocco, 2020	16
Natural compounds as regulators of miRNAs: exploring a new avenue for treating brain cancer	16
Eupatilin modulates the Mcl-1 ubiquitination status and PI3K/Akt/Foxo3a pathway to inhibit apoptosis and alleviate sepsis-induced acute myocardial injury	16
Correction: Cardioprotective effect of oleuropein in a cisplatin-induced cardiotoxicity model in rats	16
Gastroprotective and therapeutic effects of emodin on rat model of diclofenac-induced gastric ulceration	16
Genetic diversity and antimicrobial resistance of clinical Acinetobacter baumannii isolates: insights from ERIC typing	16
In silico and in vitro evaluation of the potential genotoxic impurities of vildagliptin	16
The therapeutic potential of brazilin in bladder cancer: inhibition of DNA topoisomerase I and tumor growth suppression	16
Correction: In vitro and in vivo anticancer activity of mebendazole in colon cancer: a promising drug repositioning	16
Antitumor effects of diosmetin in Ehrlich ascites carcinoma mouse model: insights into ROS-mediated mechanisms	16
Determination of beneficial effects of cuminaldehyde on hyperglycemia associated kidney malfunctions	16
GLP-1 mimetics and diabetic ketoacidosis: possible interactions and clinical consequences	15
Beneficial effect of sodium-glucose cotransporter-2 inhibitors on mortality among patients with cancer and diabetes mellitus	15
Biosynthesis and characterisations of silver nanoparticles with filamentous cyanobacterium Lyngbya sp. with in vitro antibacterial properties against MDR pathogenic bacteria	15
Patterns, outcomes, and preventability of clinically manifest drug-drug interactions in older outpatients: a subgroup analysis from a 6-year-long observational study in North India	15
Identification of the active constituents and molecular mechanism of Eulophia nuda extract in the treatment of osteoarthritis by network pharmacology, molecular modelling and experimental assays	15
Retraction Note: Efficient chemosensitizing and antimetastatic combinations of a naturally occurring trans-ferulic acid with different chemotherapies on an in vitro hepatocellular carcinoma model	15
Pharmacological targets and mechanism of baicalein in treating breast cancer: a study based on network pharmacology, molecular docking, and bioinformatics analysis	15
Enhancement of antioxidant and cytotoxicity by nanoliposome formulation of pentagamavunon-6 in breast cancer cells	15
Molecular characterization of metallo-beta-lactamase producers among carbapenem-resistant Pseudomonas aeruginosa from clinical samples in a tertiary care hospital, Lucknow, India	15
Retraction Note: A promise of nose to brain delivery of bevacizumab intranasal sol–gel formulation substantiated in rat C6 glioma model	15
Multidrug resistance, biofilm formation, and genetic determinants in diabetic foot infections from Uttar Pradesh, India: a clinical-microbiological insight from a prospective study	15
Natural products and long noncoding RNA signatures in gallbladder cancer: a review focuses on pathogenesis, diagnosis, and drug resistance	15
Mechanism of Ginkgolide B regulating Th1/Th2 balance to improving airway inflammatory response and hyperresponsiveness in asthma model mice: TLR4/NF-κB pathway	15
Screening of key active ingredients of Fuyuan Shenghua granules for the treatment of medical abortion using ingredient-target interaction and pharmacokinetics	15
Advanced glycosylation end products promote the progression of CKD-MBD in rats, and its natural inhibitor, quercetin, mitigates disease progression	15
The role of hippocampal 5-HT1D and 5-HT1F receptors on learning and memory in rats	15
The role of TLRs (microbe recognition receptor) in gastric cancer: An update	15
A narrative review and new insights into the protective effects of taurine against drug side effects	15
Analysis of clinical studies on clozapine from 2012-2022	15
Functional combination of resveratrol and midostaurin induces cytotoxicity to overcome acquired midostaurin resistance in FLT3-ITD expressing acute myeloid leukemia cells	15
Melatonin for gastric cancer treatment: where do we stand?	15
Effect of verbascoside against acute kidney injury induced by rhabdomyolysis in rats	15
Marine life as a source of anti-prostate cancer agents: an updated overview (2003–2023)	15
Irisin attenuates tubular epithelial ferroptosis in diabetic kidney disease by inhibiting the HMGB1/Nrf2/GPX4 pathway	15
Hemorrhoid risk among people with diabetes mellitus using glucose lowering agents	15
The SOX gene superfamily in oncogenesis: unraveling links to ncRNAs, key pathways, chemoresistance, and gene editing approaches	15
Identification of potential mechanisms of Schisandrin B in the treatment of idiopathic pulmonary fibrosis by integrating network pharmacology and experimental validation	15
The effects of berteroin on inflammatory mediators and antioxidant enzymes expression in human periodontal ligament cells	15
Role of Diabetes and its metabolic pathways in Epilepsy: An insight to various target approaches	15
Ivermectin repurposing for COVID-19: pharmacological and bibliometric analysis	15
Alpha-asarone relieves nasal inflammation, epithelial barrier damage, and mitochondrial damage in allergic rhinitis by inhibiting mitochondrial ROS via the SIRT1/PGC-1α pathway	15
Anticancer potential of oroxylin A: from mechanistic insight to synergistic perspectives	15
Safety and efficacy of levetiracetam and carbamazepine monotherapy in the management of pediatric focal epilepsy: a randomized clinical trial	15
Inhibitory effects characteristics of polysaccharide of Polygonati Rhizome on cytochrome P450 enzymes	15
Beyond inflammation: siRNA strategies for precision targeting in rheumatological disorders	14
Unveiling esophageal cancer treatment mechanisms: network pharmacology and molecular docking of Physcion	14
Integrative bioinformatics–machine learning–experimental validation identifies shared immunomodulatory targets in psoriasis and psoriatic arthritis and deciphers allicin’s therapeutic mechanism	14
The protective effect of rivaroxaban with or without aspirin on inflammation, oxidative stress, and platelet reactivity in isoproterenol-induced cardiac injury in rats	14
UA mitigates cisplatin-induced toxicity suggesting involvement of the KEAP1–NRF2 pathway: insights from histopathological validation, molecular docking, and molecular dynamics	14
The effect of protocatechuic acid on nephrotoxicity induced by gentamicin in rats	14
Study on the mechanism of puerarin against osteoarthritis from ferroptosis based on network pharmacology and bioinformatics	14
Exploring the mechanism of clomiphene citrate to improve ovulation disorder in PCOS rats based on follicular fluid metabolomics	14
Toxicity evaluation of ultra-diluted methotrexate (12c and 30c): an acute and subacute oral toxicity study in animals	14
Evaluating the effects of intravenous magnesium sulfate for prevention of colistin induced acute kidney injury: an open-label, placebo-controlled, block randomized clinical trial	14
Metabolomics in stress-related disorders: a systematic review and bioinformatics analysis	14
Cilostazol pretreatment prevents PTSD-related anxiety behavior through reduction of hippocampal neuroinflammation	14
Ethanol-induced liver injury is alleviated by chrysin via increasing MRP2 transporter expression and enhancing the Nrf2-mediated adaptive response	14
Fabrication of stimuli-responsive chitosan-coated levofloxacin-incorporated zeolite imidazole nanoparticles for nursing care of wound healing	14
Morusin attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis via dual activation of the Nrf2/HO-1 pathway and mTORC1-dependent GPX4 synthesis	14
Molecular mechanisms of resveratrol and its silver nanoparticle conjugate in addressing sepsis-induced lung injury	14
The effect of tamsulosin in postoperative urinary retention: a meta-analysis of randomized controlled trials	14
Network pharmacology and experimental validation to explore the effects and mechanisms of flavonoids luteolin and chrysoeriol against non‑small cell lung cancer	14
Taurine protection attenuates bisphenol-A-induced behavioral, neurochemical, and histopathological alterations in male rats	14
Puerarin raises exosomal miR- 342 - 3p by inhibiting lncRNA NEAT1 in umbilical cord mesenchymal stem cells to alleviate renal tubular epithelial cell pyroptosis in chronic renal failure	14
Cyclophosphamide-induced testicular injury: the role of chrysin in mitigating iron overload and ferroptosis	14
Cetirizine ameliorates cyclophosphamide-induced placental toxicity via modulation of TGF-β/NOX4 signaling pathway in rats	14
Quinic acid alleviates liver toxicity induced by acetaminophen in mice via anti-oxidative and anti-inflammatory effects	14
Emerging new immune checkpoint inhibitors in solid tumor immunotherapy	14
“A new order of poisonous substances”: revisiting Robert M. Glover’s dissertation on the physiological effects of bromine, chlorine, and iodine compounds	14
Combining network pharmacology and RNA sequencing to reveal the mechanism of emodin for the treatment of human neuroblastoma	14
Synergistic antibacterial activity of Phyllanthus emblica fruits and its phytocompounds with ampicillin: a computational and experimental study	14
Morusinol exerts anti-glioma activity by targeting the PI3K/AKT/mTOR signaling pathway	14
Regorafenib modulates glucose metabolism, insulin/GLP-1 signaling, and tau pathology in an STZ-induced model of Alzheimer's disease	13
The effects of ecdysterone and enalapril on nitric oxide synthesis and the markers of oxidative stress in streptozotocin-induced diabetes in rats: a comparative study	13