Nature

Article	Citations
Highly accurate protein structure prediction with AlphaFold	20633
Array programming with NumPy	11172
Factors associated with COVID-19-related death using OpenSAFELY	4571
Perovskite solar cells with atomically coherent interlayers on SnO2 electrodes	2294
Pseudo-halide anion engineering for α-FAPbI3 perovskite solar cells	2267
Efficient perovskite solar cells via improved carrier management	2137
Highly accurate protein structure prediction for the human proteome	1895
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7	1705
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls	1693
Longitudinal analyses reveal immunological misfiring in severe COVID-19	1671
SARS-CoV-2 vaccines in development	1650
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization	1584
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses	1494
Expanded encyclopaedias of DNA elements in the human and mouse genomes	1377
Detection of a SARS-CoV-2 variant of concern in South Africa	1377
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies	1356
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies	1331
Evolution of antibody immunity to SARS-CoV-2	1314
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike	1306
Towards complete and error-free genome assemblies of all vertebrate species	1266
Spike mutation D614G alters SARS-CoV-2 fitness	1259
Designing the next generation of proton-exchange membrane fuel cells	1230
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa	1200
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults	1166
Effects of extracellular matrix viscoelasticity on cellular behaviour	1141

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization	1141
Mapping genomic loci implicates genes and synaptic biology in schizophrenia	1131
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness	1123
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants	1115
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program	1093
The changing landscape of atherosclerosis	1073
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19	1037
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2	1002
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion	996
A molecular cell atlas of the human lung from single-cell RNA sequencing	992
A 20-year retrospective review of global aquaculture	987
Mobility network models of COVID-19 explain inequities and inform reopening	984
Correlates of protection against SARS-CoV-2 in rhesus macaques	981
High-dimensional characterization of post-acute sequelae of COVID-19	980
Genetic mechanisms of critical illness in COVID-19	974
Sex differences in immune responses that underlie COVID-19 disease outcomes	964
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England	954
Reproducible brain-wide association studies require thousands of individuals	947
FinnGen provides genetic insights from a well-phenotyped isolated population	946
Potently neutralizing and protective human antibodies against SARS-CoV-2	939
Cells of the adult human heart	912
Structures and distributions of SARS-CoV-2 spike proteins on intact virions	911
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection	906
A comprehensive quantification of global nitrous oxide sources and sinks	904
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization	893
Controlled growth of perovskite layers with volatile alkylammonium chlorides	883
SARS-CoV-2 is associated with changes in brain structure in UK Biobank	869
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer	860
Fibrosis: from mechanisms to medicines	852
Age-specific mortality and immunity patterns of SARS-CoV-2	845
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift	845
Photocatalytic solar hydrogen production from water on a 100-m2 scale	827
Developing fibrillated cellulose as a sustainable technological material	810
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity	803
Parallel convolutional processing using an integrated photonic tensor core	793
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity	791
SARS-CoV-2 evolution during treatment of chronic infection	775
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7	729
ChatGPT: five priorities for research	720
Strong tough hydrogels via the synergy of freeze-casting and salting out	717
Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques	714
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques	713
A large-scale binding and functional map of human RNA-binding proteins	707
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse	705
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion	701
Animal models for COVID-19	695
Exploring tissue architecture using spatial transcriptomics	689
A mobile robotic chemist	687
NASH limits anti-tumour surveillance in immunotherapy-treated HCC	686
How China could be carbon neutral by mid-century	678

Programmable photonic circuits	668
Ultralow contact resistance between semimetal and monolayer semiconductors	658
Brain charts for the human lifespan	652
Accelerated global glacier mass loss in the early twenty-first century	647
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing	642
Pattern-recognition receptors are required for NLR-mediated plant immunity	640
Antibody evasion properties of SARS-CoV-2 Omicron sublineages	639
High and rising economic costs of biological invasions worldwide	638
Promises and prospects of two-dimensional transistors	634
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity	629
Large-area display textiles integrated with functional systems	626
All-perovskite tandem solar cells with improved grain surface passivation	621
Self-powered soft robot in the Mariana Trench	616
Filling metal–organic framework mesopores with TiO2 for CO2 photoreduction	614
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia	611
Mapping the human genetic architecture of COVID-19	608
Mastering Atari, Go, chess and shogi by planning with a learned model	604
Single-particle cryo-EM at atomic resolution	603
SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo	600
SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses	598
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection	596
11 TOPS photonic convolutional accelerator for optical neural networks	593
Mutual potentiation of plant immunity by cell-surface and intracellular receptors	585
Diverse functional autoantibodies in patients with COVID-19	573
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans	573
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies	560
Negative feedback control of neuronal activity by microglia	560
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets	559
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid	559
Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5	557
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma	557
Multiple wheat genomes reveal global variation in modern breeding	555
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis	553
Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin	550
Surface reaction for efficient and stable inverted perovskite solar cells	548
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2	545
Cell-programmed nutrient partitioning in the tumour microenvironment	541
Ligand-engineered bandgap stability in mixed-halide perovskite LEDs	538
Telomere-to-telomere assembly of a complete human X chromosome	528
Lysosome-targeting chimaeras for degradation of extracellular proteins	526
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures	523
Global priority areas for ecosystem restoration	523
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia	522
Lymph protects metastasizing melanoma cells from ferroptosis	521
Cross-tissue organization of the fibroblast lineage	517
Quantum phases of matter on a 256-atom programmable quantum simulator	517
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma	506
Co-designing electronics with microfluidics for more sustainable cooling	504
BNT162b vaccines protect rhesus macaques from SARS-CoV-2	503
Area-based conservation in the twenty-first century	497
Critical advances and future opportunities in upcycling commodity polymers	491
RETRACTED ARTICLE: Room-temperature superconductivity in a carbonaceous sulfur hydride	488
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant	488
In situ Raman spectroscopy reveals the structure and dissociation of interfacial water	487
Atomic-resolution protein structure determination by cryo-EM	486
Zoonotic host diversity increases in human-dominated ecosystems	484
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters	483
Tunable strongly coupled superconductivity in magic-angle twisted trilayer graphene	481
Leading hadronic contribution to the muon magnetic moment from lattice QCD	480
Machine learning-aided engineering of hydrolases for PET depolymerization	480
Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron	477
An integrated space-to-ground quantum communication network over 4,600 kilometres	469
Satellite imaging reveals increased proportion of population exposed to floods	468
Key role of chemistry versus bias in electrocatalytic oxygen evolution	465
High-performance brain-to-text communication via handwriting	459
The coding capacity of SARS-CoV-2	458
Inference in artificial intelligence with deep optics and photonics	456
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV	456
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion	455
Unextractable fossil fuels in a 1.5 °C world	454
Reprogramming to recover youthful epigenetic information and restore vision	453
Structure-based classification of tauopathies	451
T cell responses to SARS-CoV-2 spike cross-recognize Omicron	448
A fast radio burst associated with a Galactic magnetar	442
Decade-long leukaemia remissions with persistence of CD4+ CAR T cells	441
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis	440
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates	439
A bright millisecond-duration radio burst from a Galactic magnetar	439
A molecular single-cell lung atlas of lethal COVID-19	436
High-resolution X-ray luminescence extension imaging	434

Exome sequencing and analysis of 454,787 UK Biobank participants	433
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing	433
Bending the curve of terrestrial biodiversity needs an integrated strategy	433
SARS-CoV-2 spike D614G change enhances replication and transmission	425
A dynamic stability design strategy for lithium metal solid state batteries	425
Efficient and stable blue quantum dot light-emitting diode	424
Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation	424
Swarm Learning for decentralized and confidential clinical machine learning	423
Large language models encode clinical knowledge	420
The future of food from the sea	419
Heavily mutated Omicron variant puts scientists on alert	416
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals	414
Stable room-temperature continuous-wave lasing in quasi-2D perovskite films	413
Comparative cellular analysis of motor cortex in human, marmoset and mouse	411
Climate change increases cross-species viral transmission risk	410
Bayesian reaction optimization as a tool for chemical synthesis	410
Decoding myofibroblast origins in human kidney fibrosis	408
Solar-to-hydrogen efficiency of more than 9% in photocatalytic water splitting	408
Distribution control enables efficient reduced-dimensional perovskite LEDs	408
SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans	407
Dysregulation of brain and choroid plexus cell types in severe COVID-19	407
Tunable spin-polarized correlated states in twisted double bilayer graphene	407
Shifting attention to accuracy can reduce misinformation online	404
An aged immune system drives senescence and ageing of solid organs	404
A perspective on potential antibody-dependent enhancement of SARS-CoV-2	402
Direct observation of chemical short-range order in a medium-entropy alloy	400
The power of genetic diversity in genome-wide association studies of lipids	399
Amazonia as a carbon source linked to deforestation and climate change	398
Inherited causes of clonal haematopoiesis in 97,691 whole genomes	397
The central role of DNA damage in the ageing process	395
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM	395
SARS-CoV-2 infection and persistence in the human body and brain at autopsy	393
Half a century of global decline in oceanic sharks and rays	392
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids	392
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas	391
Closed-loop recycling of polyethylene-like materials	389
Sources of particulate-matter air pollution and its oxidative potential in Europe	389
NINJ1 mediates plasma membrane rupture during lytic cell death	388
ChatGPT listed as author on research papers: many scientists disapprove	386
Ultra-bright, efficient and stable perovskite light-emitting diodes	386
Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis	383
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice	383
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape	382
The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer	381
Rare coding variants in ten genes confer substantial risk for schizophrenia	379
Thermal-expansion offset for high-performance fuel cell cathodes	376
Disease variant prediction with deep generative models of evolutionary data	373
Skilful precipitation nowcasting using deep generative models of radar	373
Quantum computational advantage with a programmable photonic processor	372
Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron	371
Correlative operando microscopy of oxygen evolution electrocatalysts	368
Global human-made mass exceeds all living biomass	368
Exome sequencing and characterization of 49,960 individuals in the UK Biobank	367
Distinct fission signatures predict mitochondrial degradation or biogenesis	364
Genome-wide enhancer maps link risk variants to disease genes	362
Evidence for 28 genetic disorders discovered by combining healthcare and research data	362
A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis	361
Additive manufacturing of silica aerogels	357
Large Chinese land carbon sink estimated from atmospheric carbon dioxide data	357
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2	356
Ageing hallmarks exhibit organ-specific temporal signatures	353
Protecting the global ocean for biodiversity, food and climate	353
A disordered rock salt anode for fast-charging lithium-ion batteries	352
Reconstruction of the full transmission dynamics of COVID-19 in Wuhan	351
‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures	349
A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis	348
Vacancy-enabled N2 activation for ammonia synthesis on an Ni-loaded catalyst	346
Elastomeric electrolytes for high-energy solid-state lithium batteries	346
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation	345
A highly stable and flexible zeolite electrolyte solid-state Li–air battery	344
Host variables confound gut microbiota studies of human disease	343
Microplastics are everywhere — but are they harmful?	342
Gasdermin D pore structure reveals preferential release of mature interleukin-1	341
Systems vaccinology of the BNT162b2 mRNA vaccine in humans	340
Quantum simulation of 2D antiferromagnets with hundreds of Rydberg atoms	340
MicroRNA sequence codes for small extracellular vesicle release and cellular retention	339
Untying the insulating and superconducting orders in magic-angle graphene	339
More than one million barriers fragment Europe’s rivers	338
The WHO estimates of excess mortality associated with the COVID-19 pandemic	336
The barley pan-genome reveals the hidden legacy of mutation breeding	335
Quantum circuits with many photons on a programmable nanophotonic chip	331
A single-cell atlas of human and mouse white adipose tissue	330
Correlated insulating states at fractional fillings of moiré superlattices	330
Discoveries in structure and physiology of mechanically activated ion channels	330
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801	327
A neuroanatomical basis for electroacupuncture to drive the vagal–adrenal axis	324
A multimodal cell census and atlas of the mammalian primary motor cortex	324
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma	324
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk	324
Survey of spiking in the mouse visual system reveals functional hierarchy	321
A stable low-temperature H2-production catalyst by crowding Pt on α-MoC	320
Orthogonal-array dynamic molecular sieving of propylene/propane mixtures	319
Scalable production of high-performing woven lithium-ion fibre batteries	317
Copper-coordinated cellulose ion conductors for solid-state batteries	317
Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron	317