Nature

Papers
(The TQCC of Nature is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Highly accurate protein structure prediction with AlphaFold16013
A pneumonia outbreak associated with a new coronavirus of probable bat origin15147
Array programming with NumPy9243
A new coronavirus associated with human respiratory disease in China8498
The mutational constraint spectrum quantified from variation in 141,456 humans5577
Virological assessment of hospitalized patients with COVID-20195353
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor4573
Factors associated with COVID-19-related death using OpenSAFELY4324
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing3183
Structural basis of receptor recognition by SARS-CoV-22939
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors2860
Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe2312
Pseudo-halide anion engineering for α-FAPbI3 perovskite solar cells2010
Perovskite solar cells with atomically coherent interlayers on SnO2 electrodes1951
The repertoire of mutational signatures in human cancer1947
Efficient perovskite solar cells via improved carrier management1900
Pan-cancer analysis of whole genomes1816
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.71650
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls1627
Highly accurate protein structure prediction for the human proteome1624
Convergent antibody responses to SARS-CoV-2 in convalescent individuals1602
Longitudinal analyses reveal immunological misfiring in severe COVID-191596
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody1591
SARS-CoV-2 vaccines in development1573
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization1516
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses1420
Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals1344
Detection of a SARS-CoV-2 variant of concern in South Africa1323
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies1270
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike1260
Evolution of antibody immunity to SARS-CoV-21237
Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins1217
Spike mutation D614G alters SARS-CoV-2 fitness1209
Human neutralizing antibodies elicited by SARS-CoV-2 infection1202
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies1199
Photocatalytic water splitting with a quantum efficiency of almost unity1159
Expanded encyclopaedias of DNA elements in the human and mouse genomes1154
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-21148
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults1117
Pathogenesis and transmission of SARS-CoV-2 in golden hamsters1106
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa1087
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants1075
Design of robust superhydrophobic surfaces1063
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization1053
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness1034
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-191011
The effect of large-scale anti-contagion policies on the COVID-19 pandemic985
Effects of extracellular matrix viscoelasticity on cellular behaviour978
Towards complete and error-free genome assemblies of all vertebrate species942
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion941
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program933
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2930
Correlates of protection against SARS-CoV-2 in rhesus macaques927
Sex differences in immune responses that underlie COVID-19 disease outcomes918
Designing the next generation of proton-exchange membrane fuel cells917
Genetic mechanisms of critical illness in COVID-19903
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England898
Mobility network models of COVID-19 explain inequities and inform reopening898
Potently neutralizing and protective human antibodies against SARS-CoV-2897
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice878
High-dimensional characterization of post-acute sequelae of COVID-19874
A molecular cell atlas of the human lung from single-cell RNA sequencing858
Structures and distributions of SARS-CoV-2 spike proteins on intact virions847
Gasdermin E suppresses tumour growth by activating anti-tumour immunity842
An engineered PET depolymerase to break down and recycle plastic bottles840
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization840
A droplet-based electricity generator with high instantaneous power density839
The changing landscape of atherosclerosis824
Mapping genomic loci implicates genes and synaptic biology in schizophrenia811
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift797
A 20-year retrospective review of global aquaculture794
Age-specific mortality and immunity patterns of SARS-CoV-2789
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection786
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets783
Effect of non-pharmaceutical interventions to contain COVID-19 in China780
Cells of the adult human heart769
Accelerated discovery of CO2 electrocatalysts using active machine learning763
A comprehensive quantification of global nitrous oxide sources and sinks753
Reproducible brain-wide association studies require thousands of individuals742
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity737
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’736
SARS-CoV-2 evolution during treatment of chronic infection720
SARS-CoV-2 is associated with changes in brain structure in UK Biobank709
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity701
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7699
Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques692
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques688
Photocatalytic solar hydrogen production from water on a 100-m2 scale682
A reference map of the human binary protein interactome676
Viral and host factors related to the clinical outcome of COVID-19675
Fibrosis: from mechanisms to medicines669
Animal models for COVID-19662
Parallel convolutional processing using an integrated photonic tensor core658
Developing fibrillated cellulose as a sustainable technological material657
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion656
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline652
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer651
Construction of a human cell landscape at single-cell level644
The evolutionary history of 2,658 cancers644
Short-range order and its impact on the CrCoNi medium-entropy alloy640
Microbiome analyses of blood and tissues suggest cancer diagnostic approach621
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing620
A large-scale binding and functional map of human RNA-binding proteins612
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse610
A mobile robotic chemist597
How China could be carbon neutral by mid-century591
Structure of replicating SARS-CoV-2 polymerase588
Antibody evasion properties of SARS-CoV-2 Omicron sublineages587
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity586
NASH limits anti-tumour surveillance in immunotherapy-treated HCC582
Strong tough hydrogels via the synergy of freeze-casting and salting out577
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I575
A structural variation reference for medical and population genetics569
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection565
The promise and challenge of therapeutic genome editing561
Population flow drives spatio-temporal distribution of COVID-19 in China558
Variability in the analysis of a single neuroimaging dataset by many teams555
Programmable photonic circuits550
Mapping the human genetic architecture of COVID-19548
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies547
A bioorthogonal system reveals antitumour immune function of pyroptosis545
Respiratory disease in rhesus macaques inoculated with SARS-CoV-2544
SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses541
Exploring tissue architecture using spatial transcriptomics540
Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli537
High and rising economic costs of biological invasions worldwide535
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans534
Pattern-recognition receptors are required for NLR-mediated plant immunity532
Ultralow contact resistance between semimetal and monolayer semiconductors530
SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo530
Accelerated global glacier mass loss in the early twenty-first century529
Infection of dogs with SARS-CoV-2529
Single-particle cryo-EM at atomic resolution528
Filling metal–organic framework mesopores with TiO2 for CO2 photoreduction524
Patterns of somatic structural variation in human cancer genomes521
Mastering Atari, Go, chess and shogi by planning with a learned model515
Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins513
Diverse functional autoantibodies in patients with COVID-19512
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis512
Self-powered soft robot in the Mariana Trench511
Rebuilding marine life510
Ultrafast machine vision with 2D material neural network image sensors510
Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin508
Promises and prospects of two-dimensional transistors507
Large-area display textiles integrated with functional systems506
Controlled growth of perovskite layers with volatile alkylammonium chlorides505
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2504
Mott and generalized Wigner crystal states in WSe2/WS2 moiré superlattices501
Mutual potentiation of plant immunity by cell-surface and intracellular receptors493
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma493
Telomere-to-telomere assembly of a complete human X chromosome492
11 TOPS photonic convolutional accelerator for optical neural networks492
Multiple wheat genomes reveal global variation in modern breeding491
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets490
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia490
All-perovskite tandem solar cells with improved grain surface passivation489
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2489
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures489
Negative feedback control of neuronal activity by microglia486
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma485
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia484
Simulation of Hubbard model physics in WSe2/WS2 moiré superlattices482
Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5479
ChatGPT: five priorities for research475
RETRACTED ARTICLE: Room-temperature superconductivity in a carbonaceous sulfur hydride469
Enhanced ferroelectricity in ultrathin films grown directly on silicon462
Massively multiplexed nucleic acid detection with Cas13458
BNT162b vaccines protect rhesus macaques from SARS-CoV-2456
Brain charts for the human lifespan456
Lymph protects metastasizing melanoma cells from ferroptosis455
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid453
Lysosome-targeting chimaeras for degradation of extracellular proteins448
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25446
A conserved dendritic-cell regulatory program limits antitumour immunity443
Global priority areas for ecosystem restoration443
Closed-loop optimization of fast-charging protocols for batteries with machine learning443
FinnGen provides genetic insights from a well-phenotyped isolated population441
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy440
Senolytic CAR T cells reverse senescence-associated pathologies439
Ligand-engineered bandgap stability in mixed-halide perovskite LEDs439
Cell-programmed nutrient partitioning in the tumour microenvironment437
Zoonotic host diversity increases in human-dominated ecosystems434
Leading hadronic contribution to the muon magnetic moment from lattice QCD427
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters426
Cross-tissue organization of the fibroblast lineage426
The coding capacity of SARS-CoV-2423
Tunable strongly coupled superconductivity in magic-angle twisted trilayer graphene421
Structures of α-synuclein filaments from multiple system atrophy421
Quantum phases of matter on a 256-atom programmable quantum simulator421
Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron420
Atomic-resolution protein structure determination by cryo-EM415
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant412
Area-based conservation in the twenty-first century412
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells412
Tunable correlated states and spin-polarized phases in twisted bilayer–bilayer graphene410
Co-designing electronics with microfluidics for more sustainable cooling409
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV408
Peripheral T cell expansion predicts tumour infiltration and clinical response404
Tunable correlated Chern insulator and ferromagnetism in a moiré superlattice402
SARS-CoV-2 spike D614G change enhances replication and transmission401
T cell responses to SARS-CoV-2 spike cross-recognize Omicron399
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes395
Composition-dependent thermodynamics of intracellular phase separation394
Wafer-scale single-crystal hexagonal boron nitride monolayers on Cu (111)393
Asynchronous carbon sink saturation in African and Amazonian tropical forests390
A fast radio burst associated with a Galactic magnetar390
A bright millisecond-duration radio burst from a Galactic magnetar390
A perspective on potential antibody-dependent enhancement of SARS-CoV-2388
SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans388
Reprogramming to recover youthful epigenetic information and restore vision388
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals388
Heavily mutated Omicron variant puts scientists on alert386
An integrated space-to-ground quantum communication network over 4,600 kilometres385
Topological polaritons and photonic magic angles in twisted α-MoO3 bilayers385
Inference in artificial intelligence with deep optics and photonics384
Key role of chemistry versus bias in electrocatalytic oxygen evolution384
Surface reaction for efficient and stable inverted perovskite solar cells384
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion380
Pathway paradigms revealed from the genetics of inflammatory bowel disease380
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing380
Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation378
A molecular single-cell lung atlas of lethal COVID-19377
High-performance brain-to-text communication via handwriting376
The online competition between pro- and anti-vaccination views376
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates375
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis375
Tunable spin-polarized correlated states in twisted double bilayer graphene374
General synthesis of two-dimensional van der Waals heterostructure arrays373
Power generation from ambient humidity using protein nanowires372
A biomimetic eye with a hemispherical perovskite nanowire array retina371
Bending the curve of terrestrial biodiversity needs an integrated strategy370
Structure-based classification of tauopathies369
Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis367
Satellite imaging reveals increased proportion of population exposed to floods364
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids363
Stable room-temperature continuous-wave lasing in quasi-2D perovskite films362
Unextractable fossil fuels in a 1.5 °C world361
Efficient and stable blue quantum dot light-emitting diode360
The future of food from the sea356
Video-based AI for beat-to-beat assessment of cardiac function356
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice355
Dysregulation of brain and choroid plexus cell types in severe COVID-19354
Inherited causes of clonal haematopoiesis in 97,691 whole genomes353
Novel tau filament fold in corticobasal degeneration353
Mechanisms and therapeutic implications of hypermutation in gliomas352
The projected timing of abrupt ecological disruption from climate change350
Critical advances and future opportunities in upcycling commodity polymers349
High-resolution X-ray luminescence extension imaging348
Decoding myofibroblast origins in human kidney fibrosis348
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape348
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