(The TQCC of
Nature is
27. The table below lists those papers that are above that threshold based on
CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
| Article | Citations |
|---|
| Ghrelin is a growth-hormone-releasing acylated peptide from stomach | 5971 |
| Virological assessment of hospitalized patients with COVID-2019 | 4931 |
| Quantum supremacy using a programmable superconducting processor | 2840 |
| A role for ghrelin in the central regulation of feeding | 2476 |
| Evolution of Asian monsoons and phased uplift of the Himalaya–Tibetan plateau since Late Miocene times | 1945 |
| Search-and-replace genome editing without double-strand breaks or donor DNA | 1863 |
| Efficient, stable and scalable perovskite solar cells using poly(3-hexylthiophene) | 1570 |
| The single-cell transcriptional landscape of mammalian organogenesis | 1501 |
| Next-generation characterization of the Cancer Cell Line Encyclopedia | 1495 |
| Scientists rise up against statistical significance | 1450 |
| Deep learning and process understanding for data-driven Earth system science | 1387 |
| Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases | 1151 |
| Single-cell transcriptomic analysis of Alzheimer’s disease | 1069 |
| The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis | 1036 |
| Recycling lithium-ion batteries from electric vehicles | 1030 |
| The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity | 998 |
| FSP1 is a glutathione-independent ferroptosis suppressor | 996 |
| Interannual extremes in the rate of rise of atmospheric carbon dioxide since 1980 | 984 |
| CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy | 968 |
| Grandmaster level in StarCraft II using multi-agent reinforcement learning | 911 |
| A view on drug resistance in cancer | 869 |
| Mapping the world’s free-flowing rivers | 865 |
| Conserved cell types with divergent features in human versus mouse cortex | 849 |
| Planar perovskite solar cells with long-term stability using ionic liquid additives | 841 |
| One thousand plant transcriptomes and the phylogenomics of green plants | 830 |
| Climate tipping points — too risky to bet against | 811 |
| A rigorous electrochemical ammonia synthesis protocol with quantitative isotope measurements | 768 |
| Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+ | 751 |
| Superconductors, orbital magnets and correlated states in magic-angle bilayer graphene | 746 |
| Metabolic regulation of gene expression by histone lactylation | 736 |
| Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial | 728 |
| The technological and economic prospects for CO2 utilization and removal | 708 |
| Adjustment to climate change is constrained by arrival date in a long-distance migrant bird | 706 |
| Evidence for moiré excitons in van der Waals heterostructures | 699 |
| Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens | 689 |
| Van der Waals integration before and beyond two-dimensional materials | 672 |
| Superconductivity at 250 K in lanthanum hydride under high pressures | 662 |
| TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion | 659 |
| Graphene and two-dimensional materials for silicon technology | 642 |
| Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution | 635 |
| Signatures of moiré-trapped valley excitons in MoSe2/WSe2 heterobilayers | 631 |
| PdMo bimetallene for oxygen reduction catalysis | 628 |
| Quantifying inactive lithium in lithium metal batteries | 609 |
| A new genomic blueprint of the human gut microbiota | 606 |
| Genetic compensation triggered by mutant mRNA degradation | 597 |
| All-optical spiking neurosynaptic networks with self-learning capabilities | 591 |
| Resolving the fibrotic niche of human liver cirrhosis at single-cell level | 590 |
| Supervised learning with quantum-enhanced feature spaces | 588 |
| Observation of moiré excitons in WSe2/WS2 heterostructure superlattices | 588 |
| Tuning element distribution, structure and properties by composition in high-entropy alloys | 586 |
| Advances in epigenetics link genetics to the environment and disease | 581 |
| Highly efficient and stable InP/ZnSe/ZnS quantum dot light-emitting diodes | 580 |
| Importance and vulnerability of the world’s water towers | 576 |
| A complete catalogue of high-quality topological materials | 568 |
| Neutrophils escort circulating tumour cells to enable cell cycle progression | 564 |
| The Integrative Human Microbiome Project | 558 |
| A human liver cell atlas reveals heterogeneity and epithelial progenitors | 551 |
| A defined commensal consortium elicits CD8 T cells and anti-cancer immunity | 544 |
| NLRP3 inflammasome activation drives tau pathology | 542 |
| Coral record of increased sediment flux to the inner Great Barrier Reef since European settlement | 535 |
| Prediction and observation of an antiferromagnetic topological insulator | 521 |
| Warming of the Antarctic ice-sheet surface since the 1957 International Geophysical Year | 519 |
| Towards spike-based machine intelligence with neuromorphic computing | 519 |
| Dry double-sided tape for adhesion of wet tissues and devices | 518 |
| Genetic strategies for improving crop yields | 515 |
| Arthropod decline in grasslands and forests is associated with landscape-level drivers | 502 |
| TOX is a critical regulator of tumour-specific T cell differentiation | 498 |
| CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy | 497 |
| Maximized electron interactions at the magic angle in twisted bilayer graphene | 496 |
| Actively personalized vaccination trial for newly diagnosed glioblastoma | 495 |
| Mapping human microbiome drug metabolism by gut bacteria and their genes | 493 |
| Catalogue of topological electronic materials | 492 |
| Genome-wide cell-free DNA fragmentation in patients with cancer | 492 |
| Individual brain organoids reproducibly form cell diversity of the human cerebral cortex | 491 |
| L1 drives IFN in senescent cells and promotes age-associated inflammation | 491 |
| From discoveries in ageing research to therapeutics for healthy ageing | 489 |
| Learning the signatures of the human grasp using a scalable tactile glove | 487 |
| Widespread global increase in intense lake phytoplankton blooms since the 1980s | 486 |
| Neoantigen-directed immune escape in lung cancer evolution | 480 |
| Resonantly hybridized excitons in moiré superlattices in van der Waals heterostructures | 478 |
| Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells | 476 |
| A single-cell molecular map of mouse gastrulation and early organogenesis | 475 |
| A clinically applicable approach to continuous prediction of future acute kidney injury | 475 |
| Pan-cancer whole-genome analyses of metastatic solid tumours | 474 |
| Electrical and synaptic integration of glioma into neural circuits | 473 |
| Aqueous Li-ion battery enabled by halogen conversion–intercalation chemistry in graphite | 470 |
| Voxelated soft matter via multimaterial multinozzle 3D printing | 466 |
| Autophagy induction via STING trafficking is a primordial function of the cGAS pathway | 463 |
| Global glacier mass changes and their contributions to sea-level rise from 1961 to 2016 | 463 |
| The bone marrow microenvironment at single-cell resolution | 459 |
| Genetic analyses of diverse populations improves discovery for complex traits | 458 |
| Superconductivity in an infinite-layer nickelate | 455 |
| Domino electroreduction of CO2 to methanol on a molecular catalyst | 454 |
| Changing climate both increases and decreases European river floods | 452 |
| Bile acid metabolites control TH17 and Treg cell differentiation | 447 |
| Molecular tuning of CO2-to-ethylene conversion | 444 |
| Visualization and targeting of LGR5+ human colon cancer stem cells | 443 |
| Unsupervised word embeddings capture latent knowledge from materials science literature | 438 |
| Managing nitrogen to restore water quality in China | 438 |
| Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth | 435 |
| TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection | 427 |
| Soil nematode abundance and functional group composition at a global scale | 418 |
| Glutamatergic synaptic input to glioma cells drives brain tumour progression | 417 |
| Skin-integrated wireless haptic interfaces for virtual and augmented reality | 417 |
| Comprehensive search for topological materials using symmetry indicators | 416 |
| The integrative biology of type 2 diabetes | 414 |
| Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules | 413 |
| Ultra-large library docking for discovering new chemotypes | 412 |
| A national experiment reveals where a growth mindset improves achievement | 410 |
| E-cadherin is required for metastasis in multiple models of breast cancer | 407 |
| Distinct fibroblast subsets drive inflammation and damage in arthritis | 404 |
| Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma | 404 |
| Earliest date for milk use in the Near East and southeastern Europe linked to cattle herding | 403 |
| MHC-II neoantigens shape tumour immunity and response to immunotherapy | 403 |
| New insights from uncultivated genomes of the global human gut microbiome | 402 |
| Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling | 392 |
| Changes in oceanic and terrestrial carbon uptake since 1982 | 391 |
| Additive manufacturing of ultrafine-grained high-strength titanium alloys | 389 |
| Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis | 389 |
| Human placenta has no microbiome but can contain potential pathogens | 388 |
| Mapping the human genetic architecture of COVID-19 | 387 |
| Altered human oligodendrocyte heterogeneity in multiple sclerosis | 386 |
| Van der Waals contacts between three-dimensional metals and two-dimensional semiconductors | 386 |
| The global distribution and trajectory of tidal flats | 385 |
| Charge order and broken rotational symmetry in magic-angle twisted bilayer graphene | 384 |
| Whole-animal connectomes of both Caenorhabditis elegans sexes | 380 |
| Drift of the major continental blocks since the Devonian | 378 |
| Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis | 372 |
| Complete biosynthesis of cannabinoids and their unnatural analogues in yeast | 369 |
| Speech synthesis from neural decoding of spoken sentences | 368 |
| Human blood vessel organoids as a model of diabetic vasculopathy | 368 |
| Machine behaviour | 368 |
| Age-related remodelling of oesophageal epithelia by mutated cancer drivers | 368 |
| NR4A transcription factors limit CAR T cell function in solid tumours | 367 |
| Scalable energy-efficient magnetoelectric spin–orbit logic | 364 |
| Restoring natural forests is the best way to remove atmospheric carbon | 355 |
| Spectroscopic signatures of many-body correlations in magic-angle twisted bilayer graphene | 355 |
| Signatures of tunable superconductivity in a trilayer graphene moiré superlattice | 353 |
| Organoid single-cell genomic atlas uncovers human-specific features of brain development | 353 |
| The landscape of somatic mutation in normal colorectal epithelial cells | 353 |
| Error mitigation extends the computational reach of a noisy quantum processor | 352 |
| Genomic characterization of metastatic breast cancers | 352 |
| Nitrosative stress drives heart failure with preserved ejection fraction | 351 |
| Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease | 351 |
| Harnessing innate immunity in cancer therapy | 350 |
| Modern microprocessor built from complementary carbon nanotube transistors | 350 |
| Rising rural body-mass index is the main driver of the global obesity epidemic in adults | 347 |
| Structural basis of STING binding with and phosphorylation by TBK1 | 345 |
| Broadband electro-optic frequency comb generation in a lithium niobate microring resonator | 343 |
| Photoredox catalysis using infrared light via triplet fusion upconversion | 341 |
| Dissociable dopamine dynamics for learning and motivation | 341 |
| Magnitude of urban heat islands largely explained by climate and population | 340 |
| Heterochromatin drives compartmentalization of inverted and conventional nuclei | 340 |
| HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation | 340 |
| Gene expression across mammalian organ development | 340 |
| Pol II phosphorylation regulates a switch between transcriptional and splicing condensates | 338 |
| An intra-tumoral niche maintains and differentiates stem-like CD8 T cells | 338 |
| Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors | 337 |
| c-Jun overexpression in CAR T cells induces exhaustion resistance | 336 |
| Deep learning for multi-year ENSO forecasts | 332 |
| Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome | 332 |
| Towards artificial general intelligence with hybrid Tianjic chip architecture | 332 |
| A quantitative approach for measuring the reservoir of latent HIV-1 proviruses | 332 |
| m6A enhances the phase separation potential of mRNA | 330 |
| Colonic epithelial cell diversity in health and inflammatory bowel disease | 330 |
| Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery | 329 |
| Atomically dispersed iron hydroxide anchored on Pt for preferential oxidation of CO in H2 | 329 |
| Normal faulting in central Tibet since at least 13.5 Myr ago | 324 |
| Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally | 324 |
| The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL | 321 |
| Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade | 321 |
| Potential roles of gut microbiome and metabolites in modulating ALS in mice | 320 |
| Incompatible and sterile insect techniques combined eliminate mosquitoes | 313 |
| Epitaxial growth of a 100-square-centimetre single-crystal hexagonal boron nitride monolayer on copper | 310 |
| A new antibiotic selectively kills Gram-negative pathogens | 309 |
| Committed emissions from existing energy infrastructure jeopardize 1.5 °C climate target | 308 |
| Superstructure control of first-cycle voltage hysteresis in oxygen-redox cathodes | 307 |
| Genomic encoding of transcriptional burst kinetics | 306 |
| Commonality despite exceptional diversity in the baseline human antibody repertoire | 303 |
| Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration | 303 |
| Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid | 300 |
| Highly structured slow solar wind emerging from an equatorial coronal hole | 299 |
| Self-verifying variational quantum simulation of lattice models | 297 |
| Fatty acid transport protein 2 reprograms neutrophils in cancer | 297 |
| Observation of room-temperature polar skyrmions | 297 |
| GABAA receptor signalling mechanisms revealed by structural pharmacology | 296 |
| Dietary methionine influences therapy in mouse cancer models and alters human metabolism | 295 |
| Organization and regulation of gene transcription | 294 |
| Multi-faceted particle pumps drive carbon sequestration in the ocean | 294 |
| Greater vulnerability to warming of marine versus terrestrial ectotherms | 292 |
| Mass balance of the Greenland Ice Sheet from 1992 to 2018 | 292 |
| The unexpected surface of asteroid (101955) Bennu | 292 |
| Millennial-scale trends in west Pacific warm pool hydrology since the Last Glacial Maximum | 291 |
| Large teams develop and small teams disrupt science and technology | 290 |
| Visualizing vibrational normal modes of a single molecule with atomically confined light | 290 |
| Decoding human fetal liver haematopoiesis | 290 |
| Damage-tolerant architected materials inspired by crystal microstructure | 288 |
| Controlled flight of a microrobot powered by soft artificial muscles | 286 |
| Distributed coding of choice, action and engagement across the mouse brain | 285 |
| Longitudinal multi-omics of host–microbe dynamics in prediabetes | 285 |
| 45.5-tesla direct-current magnetic field generated with a high-temperature superconducting magnet | 284 |
| An acute immune response underlies the benefit of cardiac stem cell therapy | 281 |
| Global warming impairs stock–recruitment dynamics of corals | 278 |
| Data-driven design of metal–organic frameworks for wet flue gas CO2 capture | 278 |
| Targeting cardiac fibrosis with engineered T cells | 275 |
| Charting cellular identity during human in vitro β-cell differentiation | 274 |
| Harnessing global fisheries to tackle micronutrient deficiencies | 273 |
| CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape | 272 |
| PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components | 271 |
| De novo design of potent and selective mimics of IL-2 and IL-15 | 270 |
| The human body at cellular resolution: the NIH Human Biomolecular Atlas Program | 270 |
| Large influence of soil moisture on long-term terrestrial carbon uptake | 269 |
| Hierarchical organization of cortical and thalamic connectivity | 269 |
| Climatic controls of decomposition drive the global biogeography of forest-tree symbioses | 268 |
| HP1 reshapes nucleosome core to promote phase separation of heterochromatin | 267 |
| Self-organization and symmetry breaking in intestinal organoid development | 267 |
| A wireless closed-loop system for optogenetic peripheral neuromodulation | 267 |
| Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid | 267 |
| Freestanding crystalline oxide perovskites down to the monolayer limit | 266 |
| Decrease in anthropogenic lead, cadmium and zinc in Greenland snows since the late 1960s | 265 |
| Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP | 265 |
| Transcription factors and 3D genome conformation in cell-fate decisions | 264 |
| High-dimensional geometry of population responses in visual cortex | 264 |
| Specialized coding of sensory, motor and cognitive variables in VTA dopamine neurons | 263 |
| Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis | 263 |
| Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice | 263 |
| CasX enzymes comprise a distinct family of RNA-guided genome editors | 263 |
| Asia’s shrinking glaciers protect large populations from drought stress | 261 |
| Site-selective and versatile aromatic C−H functionalization by thianthrenation | 261 |
| MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs | 260 |
| A distance to the Large Magellanic Cloud that is precise to one per cent | 260 |
| Total synthesis of Escherichia coli with a recoded genome | 259 |
| Neuronal vulnerability and multilineage diversity in multiple sclerosis | 258 |
| Locally renewing resident synovial macrophages provide a protective barrier for the joint | 257 |
| Observation of the nonlinear Hall effect under time-reversal-symmetric conditions | 256 |
| Mitochondrial complex III is essential for suppressive function of regulatory T cells | 255 |
| Cyclic GMP–AMP signalling protects bacteria against viral infection | 250 |
| Visualizing DNA folding and RNA in embryos at single-cell resolution | 247 |
| Plant cell-surface GIPC sphingolipids sense salt to trigger Ca2+ influx | 247 |
| Controlled modelling of human epiblast and amnion development using stem cells | 246 |
| The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape | 246 |
| Single-cell analysis reveals T cell infiltration in old neurogenic niches | 245 |
| Molybdenum-catalysed ammonia production with samarium diiodide and alcohols or water | 244 |
| Environmental flow limits to global groundwater pumping | 244 |
| Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell | 240 |
| Sex and gender analysis improves science and engineering | 239 |
| Evidence of high-temperature exciton condensation in two-dimensional atomic double layers | 239 |
| Alfvénic velocity spikes and rotational flows in the near-Sun solar wind | 239 |
| Unveiling the double-well energy landscape in a ferroelectric layer | 237 |
| Mineral protection regulates long-term global preservation of natural organic carbon | 237 |
| BCAA catabolism in brown fat controls energy homeostasis through SLC25A44 | 236 |
| Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017 | 234 |
| Giant nonreciprocal second-harmonic generation from antiferromagnetic bilayer CrI3 | 233 |
| Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity | 233 |
| Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy | 232 |
| GDF15 mediates the effects of metformin on body weight and energy balance | 231 |
| A second source of repeating fast radio bursts | 230 |
| Developmental origin, functional maintenance and genetic rescue of osteoclasts | 230 |
| Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis | 229 |
| Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis | 227 |
| A calmodulin-gated calcium channel links pathogen patterns to plant immunity | 227 |
| Synaptic proximity enables NMDAR signalling to promote brain metastasis | 227 |
| Untethered flight of an insect-sized flapping-wing microscale aerial vehicle | 226 |
| Frequency of extreme Sahelian storms tripled since 1982 in satellite observations | 225 |
| Multi-omics profiling of mouse gastrulation at single-cell resolution | 224 |
| Topologically enabled ultrahigh-Q guided resonances robust to out-of-plane scattering | 223 |
| An ultrafast symmetry switch in a Weyl semimetal | 223 |
| Tumour lineage shapes BRCA-mediated phenotypes | 223 |
| Climate–land-use interactions shape tropical mountain biodiversity and ecosystem functions | 223 |
| Discovery of a big void in Khufu’s Pyramid by observation of cosmic-ray muons | 221 |
| National food production stabilized by crop diversity | 221 |
| Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer | 221 |
| Quantum Kibble–Zurek mechanism and critical dynamics on a programmable Rydberg simulator | 221 |
| Circular ecDNA promotes accessible chromatin and high oncogene expression | 221 |
| Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction | 220 |
| Childhood cerebellar tumours mirror conserved fetal transcriptional programs | 220 |
| Niche stiffness underlies the ageing of central nervous system progenitor cells | 219 |
| Fidelity benchmarks for two-qubit gates in silicon | 217 |
| Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts | 217 |
| Predatory journals: no definition, no defence | 217 |
| A new scenario logic for the Paris Agreement long-term temperature goal | 215 |
| High frequency of shared clonotypes in human B cell receptor repertoires | 215 |
| Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 | 215 |
| Metabolic heterogeneity confers differences in melanoma metastatic potential | 215 |
| Longitudinal molecular trajectories of diffuse glioma in adults | 215 |
| Adopt a moratorium on heritable genome editing | 214 |
| Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity | 214 |
| The microbiota regulate neuronal function and fear extinction learning | 213 |
| Increasing wildfires threaten historic carbon sink of boreal forest soils | 212 |
| A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau | 212 |
| Constraints on the superconducting order parameter in Sr2RuO4 from oxygen-17 nuclear magnetic resonance | 210 |
| CD22 blockade restores homeostatic microglial phagocytosis in ageing brains | 210 |
| Resolving medulloblastoma cellular architecture by single-cell genomics | 210 |
| Nanomagnetic encoding of shape-morphing micromachines | 209 |
| Autophagic cell death restricts chromosomal instability during replicative crisis | 209 |
| Glucocorticoids promote breast cancer metastasis | 209 |
| A male-expressed rice embryogenic trigger redirected for asexual propagation through seeds | 207 |
| Taking connected mobile-health diagnostics of infectious diseases to the field | 206 |
| Wetland carbon storage controlled by millennial-scale variation in relative sea-level rise | 206 |
| DEAD-box ATPases are global regulators of phase-separated organelles | 205 |
| Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin | 205 |
| A fast radio burst localized to a massive galaxy | 204 |
| Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring | 204 |
| Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls | 204 |
| Climate and air-quality benefits of a realistic phase-out of fossil fuels | 203 |
| Climate as a risk factor for armed conflict | 202 |
| Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | 202 |
| The emergent landscape of the mouse gut endoderm at single-cell resolution | 201 |
| Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds | 201 |
| Integer factorization using stochastic magnetic tunnel junctions | 200 |
| Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death | 200 |
| Realization of a three-dimensional photonic topological insulator | 199 |
| The expanding landscape of ‘oncohistone’ mutations in human cancers | 198 |
| Two-dimensional MoS2-enabled flexible rectenna for Wi-Fi-band wireless energy harvesting | 198 |
| Observation of unconventional chiral fermions with long Fermi arcs in CoSi | 198 |
| Relative motions of hotspots in the Pacific, Atlantic and Indian Oceans since late Cretaceous time | 196 |
| Molecular recording of mammalian embryogenesis | 196 |
| Somatic mutations and clonal dynamics in healthy and cirrhotic human liver | 196 |
| How to globalize the circular economy | 195 |
| Evolution of the Sun's large-scale magnetic field since the Maunder minimum | 194 |
| Make more digital twins | 194 |
| Stem cell competition orchestrates skin homeostasis and ageing | 194 |
| Spatially resolved steady-state negative capacitance | 194 |
| No evidence for globally coherent warm and cold periods over the preindustrial Common Era | 193 |
| Bacterial cGAS-like enzymes synthesize diverse nucleotide signals | 193 |
| Sleep modulates haematopoiesis and protects against atherosclerosis | 193 |
| Dynamics of oligodendrocyte generation in multiple sclerosis | 192 |
| Global environmental consequences of twenty-first-century ice-sheet melt | 192 |
| The population history of northeastern Siberia since the Pleistocene | 190 |
| Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization | 190 |
| Evidence of topological superconductivity in planar Josephson junctions | 189 |
| Topological chiral crystals with helicoid-arc quantum states | 189 |
| Structural insights into the activation of metabotropic glutamate receptors | 188 |
| A developmental landscape of 3D-cultured human pre-gastrulation embryos | 187 |
| Multiple episodes of aridity in southern Africa since the last interglacial period | 184 |
| Magnetic and magnetic inverse spin Hall effects in a non-collinear antiferromagnet | 184 |
| Hepatocytes direct the formation of a pro-metastatic niche in the liver | 184 |
| The GenomeAsia 100K Project enables genetic discoveries across Asia | 184 |
| Stretchable pumps for soft machines | 183 |
| A universal biomolecular integral feedback controller for robust perfect adaptation | 183 |
| Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion | 183 |
| WRN helicase is a synthetic lethal target in microsatellite unstable cancers | 183 |
| Structural variation in the gut microbiome associates with host health | 182 |
| Interleukin-22 protects intestinal stem cells against genotoxic stress | 182 |
| Identification of strontium in the merger of two neutron stars | 182 |
| Decreasing overflow from the Nordic seas into the Atlantic Ocean through the Faroe Bank channel since 1950 | 181 |
| Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death | 181 |
| Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy | 181 |
| Hindered dialkyl ether synthesis with electrogenerated carbocations | 180 |
| Probing the critical nucleus size for ice formation with graphene oxide nanosheets | 179 |
| Dual modes of the carbon cycle since the Last Glacial Maximum | 178 |
| Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline | 178 |
| Permafrost collapse is accelerating carbon release | 177 |
| Isotopic evidence for the source of lead in Greenland snows since the late 1960s | 176 |
| Developmental dynamics of lncRNAs across mammalian organs and species | 176 |
| Sensitization of silicon by singlet exciton fission in tetracene | 176 |
| Spatial and temporal distribution of mass loss from the Greenland Ice Sheet since AD 1900 | 175 |
| Complex networks reveal global pattern of extreme-rainfall teleconnections | 175 |
| Inducing and exploiting vulnerabilities for the treatment of liver cancer | 175 |
| Subducting carbon | 174 |
| DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome | 174 |
| Nanosecond X-ray diffraction of shock-compressed superionic water ice | 173 |
| Colossal barocaloric effects in plastic crystals | 172 |
| Global spatial risk assessment of sharks under the footprint of fisheries | 172 |
| Time is running out for sand | 171 |
| Collapsars as a major source of r-process elements | 171 |
| A two-qubit gate between phosphorus donor electrons in silicon | 171 |
| Revisiting Antarctic ice loss due to marine ice-cliff instability | 171 |
| Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups | 171 |
| The water lily genome and the early evolution of flowering plants | 171 |
| SLC19A1 transports immunoreactive cyclic dinucleotides | 170 |
| Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation | 170 |
| Lattice anchoring stabilizes solution-processed semiconductors | 170 |
| Three-dimensional quantum Hall effect and metal–insulator transition in ZrTe5 | 169 |
| Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics | 169 |
| Chimeric peptidomimetic antibiotics against Gram-negative bacteria | 169 |
| Verified quantum information scrambling | 168 |
| A dissipatively stabilized Mott insulator of photons | 168 |
| The causes of sea-level rise since 1900 | 167 |
| Strategies for improving the sustainability of structural metals | 167 |
| Discrete attractor dynamics underlies persistent activity in the frontal cortex | 167 |
| Encoding a qubit in a trapped-ion mechanical oscillator | 167 |
| Estimating and tracking the remaining carbon budget for stringent climate targets | 167 |
| Structure and mechanogating of the mammalian tactile channel PIEZO2 | 167 |
| Compartmentalized gut lymph node drainage dictates adaptive immune responses | 167 |
| Thermoelectric performance of a metastable thin-film Heusler alloy | 167 |
| Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage | 166 |
| Photonic topological insulator in synthetic dimensions | 166 |
| Nuclear positioning facilitates amoeboid migration along the path of least resistance | 166 |
| Efficacy of MEK inhibition in patients with histiocytic neoplasms | 166 |
| LHX2- and LDB1-mediated trans interactions regulate olfactory receptor choice | 165 |
| Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex | 165 |
| Observation of the exceptional-point-enhanced Sagnac effect | 165 |
| Production of phosphorene nanoribbons | 165 |
| Chemical control of structure and guest uptake by a conformationally mobile porous material | 165 |
| Conformational transitions of a neurotensin receptor 1–Gi1 complex | 165 |
| Hydraulic control of mammalian embryo size and cell fate | 164 |
| Observing crystal nucleation in four dimensions using atomic electron tomography | 164 |
| Mitochondrial fission requires DRP1 but not dynamins | 163 |
| Synthesis and breakdown of universal metabolic precursors promoted by iron | 163 |
| Topological superconductivity in a phase-controlled Josephson junction | 163 |
| Immune evasion before tumour invasion in early lung squamous carcinogenesis | 162 |
| Gene expression cartography | 161 |
| Structural basis of assembly of the human T cell receptor–CD3 complex | 160 |
| Quantum Hall effect based on Weyl orbits in Cd3As2 | 160 |
| Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism | 159 |
| Force-induced conformational changes in PIEZO1 | 157 |
| Particle robotics based on statistical mechanics of loosely coupled components | 157 |
| How 2D semiconductors could extend Moore’s law | 156 |
| Activity of caspase-8 determines plasticity between cell death pathways | 155 |
| Localization and delocalization of light in photonic moiré lattices | 155 |
| Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma | 154 |
| Population imaging of neural activity in awake behaving mice | 154 |
| A small proton charge radius from an electron–proton scattering experiment | 154 |
| Observations of fast radio bursts at frequencies down to 400 megahertz | 154 |
| Reconstituting the transcriptome and DNA methylome landscapes of human implantation | 154 |
| Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary | 151 |
| Breast cancer cells rely on environmental pyruvate to shape the metastatic niche | 151 |
| Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease | 151 |
| A new twenty-first century science for effective epidemic response | 150 |
| Mitochondrial protein translocation-associated degradation | 149 |
| Modular click chemistry libraries for functional screens using a diazotizing reagent | 148 |
| Somatic mutations and cell identity linked by Genotyping of Transcriptomes | 148 |
| Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia | 148 |
| Predicting disruptive instabilities in controlled fusion plasmas through deep learning | 147 |
| Fast and inefficient star formation due to short-lived molecular clouds and rapid feedback | 147 |
| De novo design of bioactive protein switches | 147 |
| Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells | 147 |
| Structural basis of Notch recognition by human γ-secretase | 147 |
| Progenitors from the central nervous system drive neurogenesis in cancer | 146 |
| Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects | 146 |
| Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2 | 146 |
| Mobile PEAR transcription factors integrate positional cues to prime cambial growth | 146 |
| Roaring by red deer stags advances the date of oestrus in hinds | 145 |
| SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis | 145 |
| Secondary organic aerosol reduced by mixture of atmospheric vapours | 145 |
| VISTA is an acidic pH-selective ligand for PSGL-1 | 145 |
| To catch and reverse a quantum jump mid-flight | 144 |
| High levels of auxin signalling define the stem-cell organizer of the vascular cambium | 144 |
| Site-specific allylic C–H bond functionalization with a copper-bound N-centred radical | 143 |
| Conformation space of a heterodimeric ABC exporter under turnover conditions | 143 |
| Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia | 143 |
| Multiplex chromatin interactions with single-molecule precision | 143 |
| Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer | 143 |
| Cortical pattern generation during dexterous movement is input-driven | 143 |
| The prevalence of Plasmodium falciparum in sub-Saharan Africa since 1900 | 142 |
| Convergent estimates of marine nitrogen fixation | 142 |
| A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1 | 142 |
| Large magnetic gap at the Dirac point in Bi2Te3/MnBi2Te4 heterostructures | 142 |
| Architecture of autoinhibited and active BRAF–MEK1–14-3-3 complexes | 141 |
| Rubisco condensate formation by CcmM in β-carboxysome biogenesis | 140 |
| Attosecond angular streaking and tunnelling time in atomic hydrogen | 140 |
| Efficient molecular doping of polymeric semiconductors driven by anion exchange | 139 |
| Anatomy and resilience of the global production ecosystem | 139 |
| Thermal stress induces glycolytic beige fat formation via a myogenic state | 139 |
| Diverse and robust molecular algorithms using reprogrammable DNA self-assembly | 138 |
| Teraelectronvolt emission from the γ-ray burst GRB 190114C | 137 |
| Twentieth-century hydroclimate changes consistent with human influence | 137 |
| Somatic inflammatory gene mutations in human ulcerative colitis epithelium | 136 |
| High-temperature superconductivity in monolayer Bi2Sr2CaCu2O8+δ | 136 |
| H+ transport is an integral function of the mitochondrial ADP/ATP carrier | 136 |
| Light-wave dynamic control of magnetism | 135 |
| Structural basis of coreceptor recognition by HIV-1 envelope spike | 135 |
| Identifying the pathways required for coping behaviours associated with sustained pain | 135 |
| Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus | 134 |
| Why deep-learning AIs are so easy to fool | 133 |
| Intrinsically stable organic solar cells under high-intensity illumination | 133 |
| Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport | 132 |
| Metal-free directed sp2-C–H borylation | 132 |
| The corona contracts in a black-hole transient | 132 |
| α-Ketoglutarate links p53 to cell fate during tumour suppression | 132 |
| Atypical behaviour and connectivity in SHANK3-mutant macaques | 132 |
| Holistic prediction of enantioselectivity in asymmetric catalysis | 131 |
| Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline | 131 |
| Identification of an ATP-sensitive potassium channel in mitochondria | 131 |
| Molecular streaming and its voltage control in ångström-scale channels | 130 |
| Deep fracture fluids isolated in the crust since the Precambrian era | 129 |
| Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes | 129 |
| Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing | 129 |
| Regulation of α-synuclein by chaperones in mammalian cells | 129 |
| California’s methane super-emitters | 128 |
| Air pollution: a global problem needs local fixes | 127 |
| Observation of thermal Hawking radiation and its temperature in an analogue black hole | 127 |
| High-temperature bulk metallic glasses developed by combinatorial methods | 127 |
| Smoothened stimulation by membrane sterols drives Hedgehog pathway activity | 127 |
| Restoration of brain circulation and cellular functions hours post-mortem | 127 |
| Real-time discrimination of earthquake foreshocks and aftershocks | 126 |
| Object-vector coding in the medial entorhinal cortex | 126 |
| A new species of Homo from the Late Pleistocene of the Philippines | 126 |
| Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET | 126 |
| Genetic predisposition to mosaic Y chromosome loss in blood | 126 |
| Single-neuron perturbations reveal feature-specific competition in V1 | 125 |
| Enhanced intrinsic photovoltaic effect in tungsten disulfide nanotubes | 124 |
| Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour | 124 |
| Windborne long-distance migration of malaria mosquitoes in the Sahel | 124 |
| FACT caught in the act of manipulating the nucleosome | 124 |
| A volumetric display for visual, tactile and audio presentation using acoustic trapping | 123 |
| Mechanisms of RALF peptide perception by a heterotypic receptor complex | 123 |
| Reverse-engineering the locomotion of a stem amniote | 123 |
| Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques | 123 |
| Hyperbolic lattices in circuit quantum electrodynamics | 122 |
| How to win public support for a global carbon tax | 122 |
| FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing | 122 |
| Visualizing Poiseuille flow of hydrodynamic electrons | 122 |
| Observed controls on resilience of groundwater to climate variability in sub-Saharan Africa | 122 |
| Exome sequencing of Finnish isolates enhances rare-variant association power | 122 |
| PhDs: the tortuous truth | 121 |
| Non-Hermitian ring laser gyroscopes with enhanced Sagnac sensitivity | 121 |
| Introns are mediators of cell response to starvation | 121 |
| Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling | 121 |
| Molecular architecture of lineage allocation and tissue organization in early mouse embryo | 121 |
| Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function | 121 |
| Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors | 120 |
| Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut | 120 |
| GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites | 120 |
| Millennial-scale changes in North Atlantic circulation since the last glaciation | 119 |
| Cavity quantum electrodynamics with atom-like mirrors | 119 |
| A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1 | 119 |
| Ionic-surfactant-mediated electro-dewetting for digital microfluidics | 118 |
| Oxytocin-dependent reopening of a social reward learning critical period with MDMA | 118 |
| NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling | 118 |
| Analysis of the B cell receptor repertoire in six immune-mediated diseases | 118 |
| Insights into ubiquitin chain architecture using Ub-clipping | 117 |
| Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs | 117 |
| Mid-latitude net precipitation decreased with Arctic warming during the Holocene | 116 |
| Chromatin structure dynamics during the mitosis-to-G1 phase transition | 116 |
| Spliceosomal disruption of the non-canonical BAF complex in cancer | 116 |
| Increase in CFC-11 emissions from eastern China based on atmospheric observations | 116 |
| The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs | 116 |
| Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis | 116 |
| Hominin occupation of the Chinese Loess Plateau since about 2.1 million years ago | 115 |
| Comprehensive single-cell transcriptome lineages of a proto-vertebrate | 115 |
| Anaerobic oxidation of ethane by archaea from a marine hydrocarbon seep | 115 |
| Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis | 115 |
| IL-17a promotes sociability in mouse models of neurodevelopmental disorders | 115 |
| Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity | 115 |
| FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes | 114 |
| Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy | 114 |
| Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium | 114 |
| Meridional flows in the disk around a young star | 113 |
| Make scientific data FAIR | 113 |
| High performance from extraordinarily thick organic light-emitting diodes | 113 |
| Stabilization of chromatin topology safeguards genome integrity | 113 |
| TMK1-mediated auxin signalling regulates differential growth of the apical hook | 113 |
| Genomic insights into the 2016–2017 cholera epidemic in Yemen | 113 |
| Colouration by total internal reflection and interference at microscale concave interfaces | 112 |
| Large electrocaloric effects in oxide multilayer capacitors over a wide temperature range | 112 |
| scSLAM-seq reveals core features of transcription dynamics in single cells | 112 |
| Wilderness areas halve the extinction risk of terrestrial biodiversity | 111 |
| Climate change and overfishing increase neurotoxicant in marine predators | 111 |
| Alcohol metabolism contributes to brain histone acetylation | 111 |
| Regulation of lifespan by neural excitation and REST | 111 |
| Chang’E-4 initial spectroscopic identification of lunar far-side mantle-derived materials | 111 |
| The ADP/ATP translocase drives mitophagy independent of nucleotide exchange | 111 |
| A wide star–black-hole binary system from radial-velocity measurements | 111 |
| Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis | 111 |
| Mapping 123 million neonatal, infant and child deaths between 2000 and 2017 | 111 |
| Electrochemically reconfigurable architected materials | 110 |
| Time-resolved protein activation by proximal decaging in living systems | 110 |
| Energy of the 229Th nuclear clock transition | 110 |
| Developmental ROS individualizes organismal stress resistance and lifespan | 110 |
| The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis | 110 |
| Structural basis of ligand recognition at the human MT1 melatonin receptor | 110 |
| Astrophysical detection of the helium hydride ion HeH+ | 109 |
| Atomic-scale imaging of a 27-nuclear-spin cluster using a quantum sensor | 109 |
| RETRACTED ARTICLE: Complex societies precede moralizing gods throughout world history | 109 |
| A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate | 109 |
| Birth date and sporting success | 108 |
| A gated quantum dot strongly coupled to an optical microcavity | 108 |
| Light-entrained and brain-tuned circadian circuits regulate ILC3s and gut homeostasis | 108 |
| HIF-1α metabolically controls collagen synthesis and modification in chondrocytes | 108 |
| Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury | 108 |
| A very-high-energy component deep in the γ-ray burst afterglow | 108 |
| Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi | 107 |
| Early fungi from the Proterozoic era in Arctic Canada | 107 |
| Machine learning in electronic-quantum-matter imaging experiments | 107 |
| Structures of influenza A virus RNA polymerase offer insight into viral genome replication | 107 |
| Opposing T cell responses in experimental autoimmune encephalomyelitis | 107 |
| Internal state dynamics shape brainwide activity and foraging behaviour | 107 |
| Programmable design of orthogonal protein heterodimers | 107 |
| In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer | 106 |
| TRAIP is a master regulator of DNA interstrand crosslink repair | 105 |
| Structure of the mitochondrial import gate reveals distinct preprotein paths | 105 |
| Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming | 105 |
| Skin sensors are the future of health care | 104 |
| Immunization: vital progress, unfinished agenda | 104 |
| Crosslinking ionic oligomers as conformable precursors to calcium carbonate | 104 |
| Selective triplet exciton formation in a single molecule | 104 |
| Prepare river ecosystems for an uncertain future | 104 |
| Subthreshold firing in Mott nanodevices | 104 |
| A dominant population of optically invisible massive galaxies in the early Universe | 104 |
| Structural basis of lipopolysaccharide extraction by the LptB2FGC complex | 103 |
| Sensorimotor experience remaps visual input to a heading-direction network | 103 |
| Temporal and spectral fingerprints of ultrafast all-coherent spin switching | 103 |
| Structure and autoregulation of a P4-ATPase lipid flippase | 103 |
| Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer | 103 |
| A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases | 103 |
| Designing minimal and scalable insect-inspired multi-locomotion millirobots | 102 |
| Metamorphism and the evolution of plate tectonics | 102 |
| Ultrafast spin-lasers | 102 |
| The low-energy Goldstone mode in a trapped dipolar supersolid | 102 |
| Supersolid symmetry breaking from compressional oscillations in a dipolar quantum gas | 102 |
| Discovery of a pathway for terminal-alkyne amino acid biosynthesis | 102 |
| Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis | 102 |
| Trace metals in Antarctic snows since 1914 | 101 |
| Anthropogenic biases in chemical reaction data hinder exploratory inorganic synthesis | 101 |
| Timing of archaic hominin occupation of Denisova Cave in southern Siberia | 101 |
| Resonant microwave-mediated interactions between distant electron spins | 101 |
| Observation of inverse Compton emission from a long γ-ray burst | 101 |
| Axionic charge-density wave in the Weyl semimetal (TaSe4)2I | 100 |
| Nonreciprocal control and cooling of phonon modes in an optomechanical system | 99 |
| Natural selection on the Arabidopsis thaliana genome in present and future climates | 99 |
| The U1 spliceosomal RNA is recurrently mutated in multiple cancers | 99 |
| Visualizing electrostatic gating effects in two-dimensional heterostructures | 99 |
| Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma | 99 |
| Frontal cortex neuron types categorically encode single decision variables | 98 |
| Structure of the complex I-like molecule NDH of oxygenic photosynthesis | 98 |
| Structural basis of nucleosome recognition and modification by MLL methyltransferases | 98 |
| Thermodynamic signatures of quantum criticality in cuprate superconductors | 98 |
| Deacylative transformations of ketones via aromatization-promoted C–C bond activation | 97 |
| Structural colour using organized microfibrillation in glassy polymer films | 97 |
| Dietary salt promotes cognitive impairment through tau phosphorylation | 97 |
| UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis | 97 |
| Absence of a thick atmosphere on the terrestrial exoplanet LHS 3844b | 97 |
| Mapping changes in housing in sub-Saharan Africa from 2000 to 2015 | 97 |
| The ultrafast Einstein–de Haas effect | 97 |
| Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease | 97 |
| Mandate vaccination with care | 96 |
| Climate change and tropical cyclone trend | 96 |
| Excised linear introns regulate growth in yeast | 96 |
| Electrolytic vascular systems for energy-dense robots | 96 |
| Optical clock comparison for Lorentz symmetry testing | 96 |
| Age estimates for hominin fossils and the onset of the Upper Palaeolithic at Denisova Cave | 96 |
| Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy | 96 |
| Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny | 96 |
| Challenges in evidencing the earliest traces of life | 95 |
| Stellar mergers as the origin of magnetic massive stars | 95 |
| Earliest hunting scene in prehistoric art | 95 |
| Key role for CTCF in establishing chromatin structure in human embryos | 95 |
| Collapsing glaciers threaten Asia’s water supplies | 94 |
| Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis | 94 |
| Asymmetric lysosome inheritance predicts activation of haematopoietic stem cells | 94 |
| High-resolution lineage tracking reveals travelling wave of adaptation in laboratory yeast | 94 |
| PU.1 controls fibroblast polarization and tissue fibrosis | 94 |
| Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes | 94 |
| Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex | 93 |
| An ultra-stable gold-coordinated protein cage displaying reversible assembly | 93 |
| Structure of the post-translational protein translocation machinery of the ER membrane | 93 |
| Genetic induction and mechanochemical propagation of a morphogenetic wave | 92 |
| Accretion of a giant planet onto a white dwarf star | 92 |
| Non-line-of-sight imaging using phasor-field virtual wave
optics | 92 |
| Emergence of tissue-like mechanics from fibrous networks confined by close-packed cells | 92 |
| Phytoplankton productivity in the North Pacific ocean since 1900 and implications for absorption of anthropogenic CO2 | 91 |
| Quantum critical behaviour at the many-body localization transition | 91 |
| Cryo-EM structures of apo and antagonist-bound human Cav3.1 | 91 |
| Thermal conductance of single-molecule junctions | 91 |
| A unified mechanism for intron and exon definition and back-splicing | 91 |
| The fundamental role of chromatin loop extrusion in physiological V(D)J recombination | 91 |
| An apical hypoxic niche sets the pace of shoot meristem activity | 91 |
| Real-space charge-density imaging with sub-ångström resolution by four-dimensional electron microscopy | 91 |
| A large source of cloud condensation nuclei from new particle formation in the tropics | 91 |
| An antiaromatic-walled nanospace | 90 |
| Generation of stable heading representations in diverse visual scenes | 90 |
| Distinct modes of cell competition shape mammalian tissue morphogenesis | 90 |
| Structure and drug resistance of the Plasmodium falciparum transporter PfCRT | 90 |
| No detection of methane on Mars from early ExoMars Trace Gas Orbiter observations | 90 |
| Patch repair of deep wounds by mobilized fascia | 89 |
| Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome | 89 |
| Onset of differentiation is post-transcriptionally controlled in adult neural stem cells | 89 |
| Tracing the origin of adult intestinal stem cells | 89 |
| β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration | 89 |
| Surface erosion events controlled the evolution of plate tectonics on Earth | 89 |
| Structural basis of unidirectional export of lipopolysaccharide to the cell surface | 89 |
| Formation of massive black holes in rapidly growing pre-galactic gas clouds | 89 |
| What’s next for Registered Reports? | 88 |
| Five decades of northern land carbon uptake revealed by the interhemispheric CO2 gradient | 88 |
| Lipid signalling drives proteolytic rewiring of mitochondria by YME1L | 88 |
| Spin–orbit-driven band inversion in bilayer graphene by the van der Waals proximity effect | 88 |
| Metastatic-niche labelling reveals parenchymal cells with stem features | 88 |
| RETRACTED ARTICLE: A 10 per cent increase in global land evapotranspiration from 2003 to 2019 | 88 |
| A sensory appendage protein protects malaria vectors from pyrethroids | 88 |
| SETD3 is an actin histidine methyltransferase that prevents primary dystocia | 88 |
| Martian dust storm impact on atmospheric H2O and D/H observed by ExoMars Trace Gas Orbiter | 88 |
| Continued decline of total ozone over Halley, Antarctica, since 1985 | 87 |
| The reality behind solar power’s next star material | 87 |
| Peptide ligation by chemoselective aminonitrile coupling in water | 87 |
| Waveguide-coupled single collective excitation of atomic arrays | 87 |
| Transcriptional cofactors display specificity for distinct types of core promoters | 87 |
| Phylogenetic evidence for Sino-Tibetan origin in northern China in the Late Neolithic | 86 |
| Genome editing retraces the evolution of toxin resistance in the monarch butterfly | 86 |
| RGF1 controls root meristem size through ROS signalling | 86 |
| A weak topological insulator state in quasi-one-dimensional bismuth iodide | 86 |
| 78Ni revealed as a doubly magic stronghold against nuclear deformation | 86 |
| Chiral twisted van der Waals nanowires | 85 |
| Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis | 85 |
| Modulation of cardiac ryanodine receptor 2 by calmodulin | 85 |
| Resolving the energy levels of a nanomechanical oscillator | 85 |
| An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp | 85 |
| Lactonization as a general route to β-C(sp3)–H functionalization | 85 |
| XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity | 85 |
| Probing the energetic particle environment near the Sun | 85 |
| Broadening not strengthening of the Agulhas Current since the early 1990s | 84 |
| Weak average liquid-cloud-water response to anthropogenic aerosols | 84 |
| Calicivirus VP2 forms a portal-like assembly following receptor engagement | 84 |
| Parallel entangling operations on a universal ion-trap quantum computer | 84 |
| Predator-induced collapse of niche structure and species coexistence | 84 |
| Insights into the assembly and activation of the microtubule nucleator γ-TuRC | 84 |
| Fundamental roles of chromatin loop extrusion in antibody class switching | 83 |
| Hidden resilience and adaptive dynamics of the global online hate ecology | 83 |
| De novo protein design by citizen scientists | 83 |
| Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America | 83 |
| Rein in the four horsemen of irreproducibility | 82 |
| Three pitfalls to avoid in machine learning | 82 |
| An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin | 82 |
| Neural signatures of sleep in zebrafish | 82 |
| Imaging magnetic polarons in the doped Fermi–Hubbard model | 82 |
| H2A.Z facilitates licensing and activation of early replication origins | 82 |
| Computational periscopy with an ordinary digital camera | 81 |
| Chemotaxis as a navigation strategy to boost range expansion | 81 |
| Neogene cooling driven by land surface reactivity rather than increased weathering fluxes | 81 |
| Mechanism of DNA translocation underlying chromatin remodelling by Snf2 | 81 |
| Transposon molecular domestication and the evolution of the RAG recombinase | 81 |
| KRAS4A directly regulates hexokinase 1 | 81 |
| Non-photosynthetic predators are sister to red algae | 80 |
| Mediterranean winter rainfall in phase with African monsoons during the past 1.36 million years | 80 |
| An allosteric mechanism for potent inhibition of human ATP-citrate lyase | 79 |
| Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin catalysed glutamylation | 79 |
| Structural insights into the mechanism of human soluble guanylate cyclase | 78 |
| Interlayer exciton laser of extended spatial coherence in atomically thin heterostructures | 78 |
| Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome | 78 |
| p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis | 78 |
| Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase | 78 |
| A general theoretical and experimental framework for nanoscale electromagnetism | 77 |
| Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle | 77 |
| PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress | 77 |
| Tripled yield in direct-drive laser fusion through statistical modelling | 77 |
| Modified structure of protons and neutrons in correlated pairs | 76 |
| Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM | 76 |
| Pluripotency and the origin of animal multicellularity | 76 |
| Genome–lamina interactions are established de novo in the early mouse embryo | 76 |
| A gut-to-brain signal of fluid osmolarity controls thirst satiation | 76 |
| Core crystallization and pile-up in the cooling sequence of evolving white dwarfs | 76 |
| Modular and tunable biological feedback control using a de novo protein switch | 76 |
| Forearc carbon sink reduces long-term volatile recycling into the mantle | 76 |
| Observation of two-neutrino double electron capture in 124Xe with XENON1T | 75 |
| Resonant electro-optic frequency comb | 75 |
| Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission | 75 |
| Late steps in bacterial translation initiation visualized using time-resolved cryo-EM | 75 |
| LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer | 75 |
| Human gut bacteria contain acquired interbacterial defence systems | 75 |
| Immunity to commensal papillomaviruses protects against skin cancer | 75 |
| Amino-acid Sequences of Kangaroo Myoglobin and Haemoglobin and the Date of Marsupial-Eutherian Divergence | 74 |
| Priorities for the next 10 years of human microbiome research | 74 |
| Global change drives modern plankton communities away from the pre-industrial state | 74 |
| Twofold expansion of the Indo-Pacific warm pool warps the MJO life cycle | 74 |
| Giant thermal Hall conductivity in the pseudogap phase of cuprate superconductors | 74 |
| Nine-hour X-ray quasi-periodic eruptions from a low-mass black hole galactic nucleus | 74 |
| An integrative systems genetic analysis of mammalian lipid metabolism | 74 |
| Globally resolved surface temperatures since the Last Glacial Maximum | 73 |
| How much can forests fight climate change? | 73 |
| Memory editing from science fiction to clinical practice | 73 |
| Information gerrymandering and undemocratic decisions | 73 |
| Position and momentum mapping of vibrations in graphene nanostructures | 73 |
| Bacterial biodiversity drives the evolution of CRISPR-based phage resistance | 73 |
| Flower isoforms promote competitive growth in cancer | 73 |
| Inflation of 430-parsec bipolar radio bubbles in the Galactic Centre by an energetic event | 73 |
| Increasing subtropical North Pacific Ocean nitrogen fixation since the Little Ice Age | 72 |
| Tracing the US opioid crisis to its roots | 72 |
| A potassium channel β-subunit couples mitochondrial electron transport to sleep | 72 |
| Random anti-lasing through coherent perfect absorption in a disordered medium | 72 |
| Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects | 72 |
| Structure and mechanism of the cation–chloride cotransporter NKCC1 | 72 |
| A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene | 72 |
| Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products | 72 |
| BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells | 72 |
| Isomerization of BRCA1–BARD1 promotes replication fork protection | 72 |
| MHC class II proteins mediate cross-species entry of bat influenza viruses | 72 |
| Last appearance of Homo erectus at Ngandong, Java, 117,000–108,000 years ago | 72 |
| HBO1 is required for the maintenance of leukaemia stem cells | 72 |
| China’s tree-planting drive could falter in a warming world | 71 |
| Temporal plasticity of apical progenitors in the developing mouse neocortex | 71 |
| Stationary entangled radiation from micromechanical motion | 71 |
| A widespread coral-infecting apicomplexan with chlorophyll biosynthesis genes | 71 |
| Global satellite-observed daily vertical migrations of ocean animals | 71 |
| Precise therapeutic gene correction by a simple nuclease-induced double-stranded break | 71 |
| General relativistic orbital decay in a seven-minute-orbital-period eclipsing binary system | 71 |
| Disinformation’s spread: bots, trolls and all of us | 70 |
| Quaternary-centre-guided synthesis of complex polycyclic terpenes | 70 |
| Entanglement of bosonic modes through an engineered exchange interaction | 70 |
| Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism | 70 |
| FOXK1 and FOXK2 regulate aerobic glycolysis | 70 |
| Signatures of a jet cocoon in early spectra of a supernova associated with a γ-ray burst | 70 |
| Classify viruses — the gain is worth the pain | 69 |
| Light-driven anaerobic microbial oxidation of manganese | 69 |
| Architecture of the mycobacterial type VII secretion system | 69 |
| Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia | 69 |
| Structure of the Fanconi anaemia monoubiquitin ligase complex | 69 |
| Put equity first in climate adaptation | 68 |
| Southward propagation of Nazca subduction along the Andes | 68 |
| Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding | 68 |
| Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei | 68 |
| Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation | 68 |
| Similar scaling laws for earthquakes and Cascadia slow-slip events | 67 |
| Controlling protein assembly on inorganic crystals through designed protein interfaces | 67 |
| Design and evolution of an enzyme with a non-canonical organocatalytic mechanism | 67 |
| Cholera toxin promotes pathogen acquisition of host-derived nutrients | 66 |
| Four steps to food security for swelling cities | 66 |
| Why and where an HIV cure is needed and how it might be achieved | 66 |
| Electrical resistivity across a nematic quantum critical point | 66 |
| Humans are driving one million species to extinction | 65 |
| Straightforward access to N-trifluoromethyl amides, carbamates, thiocarbamates and ureas | 65 |
| Neural circuits underlying a psychotherapeutic regimen for fear disorders | 65 |
| Cryo-EM structure of the spinach cytochrome b6 f complex at 3.6 Å resolution | 65 |
| Human origins in a southern African palaeo-wetland and first migrations | 65 |
| Ultrahigh-pressure isostructural electronic transitions in hydrogen | 65 |
| A magnetar-powered X-ray transient as the aftermath of a binary neutron-star merger | 65 |
| Helical van der Waals crystals with discretized Eshelby twist | 65 |
| Confinement of atomically defined metal halide sheets in a metal–organic framework | 65 |
| The molecular landscape of ETMR at diagnosis and relapse | 65 |
| Tainted water: the scientists tracing thousands of fluorinated chemicals in our environment | 64 |
| Migrant memory B cells secrete luminal antibody in the vagina | 64 |
| A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila | 64 |
| Disruption of the Orion molecular core 1 by wind from the massive star θ1 Orionis C | 64 |
| Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1 | 64 |
| Near-Sun observations of an F-corona decrease and K-corona fine structure | 64 |
| Direct laboratory determination of the 187Re half-life | 63 |
| Why the US–China trade war spells disaster for the Amazon | 63 |
| Rapid expansion of Greenland’s low-permeability ice slabs | 63 |
| PGRMC2 is an intracellular haem chaperone critical for adipocyte function | 63 |
| Growth dynamics in naturally progressing chronic lymphocytic leukaemia | 63 |
| Electric field correlation measurements on the electromagnetic vacuum state | 62 |
| Near-field photonic cooling through control of the chemical potential of photons | 62 |
| An X-ray chimney extending hundreds of parsecs above and below the Galactic Centre | 62 |
| Visualization of clustered protocadherin neuronal self-recognition complexes | 62 |
| MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment | 62 |
| Habenular TCF7L2 links nicotine addiction to diabetes | 62 |
| The CRISPR-baby scandal: what’s next for human gene-editing | 61 |
| Insect egg size and shape evolve with ecology but not developmental rate | 61 |
| RETRACTED ARTICLE: Living annulative π-extension polymerization for graphene nanoribbon synthesis | 61 |
| Two-million-year-old snapshots of atmospheric gases from Antarctic ice | 61 |
| Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid | 61 |
| Social dilemmas among unequals | 60 |
| Death march of a segmented and trilobate bilaterian elucidates early animal evolution | 60 |
| Large hydropower and water-storage potential in future glacier-free basins | 60 |
| UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity | 60 |
| Controlling organization and forces in active matter through optically defined boundaries | 60 |
| Enamel proteome shows that Gigantopithecus was an early diverging pongine | 60 |
| Cooling and freshening of the subpolar North Atlantic Ocean since the 1960s | 59 |
| Millions of black people affected by racial bias in health-care algorithms | 59 |
| Observation of fermion-mediated interactions between bosonic atoms | 59 |
| Measurement of quantum back action in the audio band at room temperature | 59 |
| Structural basis of ligand recognition and self-activation of orphan GPR52 | 59 |
| India's and Australia's pole path since the late Mesozoic and the India–Asia collision | 58 |
| Recalibration of path integration in hippocampal place cells | 58 |
| Structure of the IFNγ receptor complex guides design of biased agonists | 58 |
| A sensor kinase controls turgor-driven plant infection by the rice blast fungus | 58 |
| Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system | 58 |
| Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex | 58 |
| Positive selection at sites of multiple amino acid replacements since rat–mouse divergence | 57 |
| Hundreds of extreme self-citing scientists revealed in new database | 57 |
| Analogue quantum chemistry simulation | 57 |
| Global entangling gates on arbitrary ion qubits | 57 |
| Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis | 57 |
| Structure of the human metapneumovirus polymerase phosphoprotein complex | 57 |
| Author Correction: Virological assessment of hospitalized patients with COVID-2019 | 57 |
| Beware of plausible predictions of fantasy materials | 56 |
| Antarctic offshore polynyas linked to Southern Hemisphere climate anomalies | 56 |
| A new Miocene ape and locomotion in the ancestor of great apes and humans | 56 |
| Capture of nebular gases during Earth’s accretion is preserved in deep-mantle neon | 56 |
| Neuromodulatory control of localized dendritic spiking in critical period cortex | 55 |
| Aridity is expressed in river topography globally | 55 |
| Tracking the precession of single nuclear spins by weak measurements | 55 |
| A hexagonal planar transition-metal complex | 55 |
| DNA damage detection in nucleosomes involves DNA register shifting | 55 |
| p38γ is essential for cell cycle progression and liver tumorigenesis | 55 |
| Late Middle Pleistocene Levallois stone-tool technology in southwest China | 55 |
| An AI boost for clinical trials | 54 |
| How China will protect one-quarter of its land | 54 |
| Phonon heat transfer across a vacuum through quantum fluctuations | 54 |
| Coherent spin-state transfer via Heisenberg exchange | 54 |
| Constraints on global mean sea level during Pliocene warmth | 54 |
| Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase | 54 |
| A rapidly changing jet orientation in the stellar-mass black-hole system V404 Cygni | 54 |
| U–Pb-dated flowstones restrict South African early hominin record to dry climate phases | 54 |
| Impaired cell fate through gain-of-function mutations in a chromatin reader | 54 |
| The formation of Jupiter’s diluted core by a giant impact | 53 |
| Sound velocity of CaSiO3 perovskite suggests the presence of basaltic crust in the Earth’s lower mantle | 53 |
| Carrier-resolved photo-Hall effect | 53 |
| Maternal vitamin C regulates reprogramming of DNA methylation and germline development | 53 |
| RETRACTED ARTICLE: Global analysis of streamflow response to forest management | 52 |
| Rotation tracking of genome-processing enzymes using DNA origami rotors | 52 |
| Polymers with controlled assembly and rigidity made with click-functional peptide bundles | 52 |
| CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle | 52 |
| Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle | 52 |
| A new date for the Taupo eruption, New Zealand | 51 |
| 15-Myr periodicity in the frequency of geomagnetic reversals since 100 Myr | 51 |
| Mapping orbital changes upon electron transfer with tunnelling microscopy on insulators | 51 |
| Sampling the volatile-rich transition zone beneath Bermuda | 51 |
| Evolution of the new head by gradual acquisition of neural crest regulatory circuits | 51 |
| Seeing mesoatomic distortions in soft-matter crystals of a double-gyroid block copolymer | 51 |
| The centrosome protein AKNA regulates neurogenesis via microtubule organization | 51 |
| Why young climate activists have captured the world’s attention | 50 |
| Women who win prizes get less money and prestige | 50 |
| Quantum-enhanced sensing of a single-ion mechanical oscillator | 50 |
| Greenland melt drives continuous export of methane from the ice-sheet bed | 50 |
| Direct observation of incommensurate magnetism in Hubbard chains | 50 |
| Needle-like structures discovered on positively charged lightning branches | 50 |
| Selecting Rhizobium for acid, infertile soils of the tropics | 49 |
| Uncertainties in tropical-cyclone translation speed | 49 |
| Isotopic constraint on the twentieth-century increase in tropospheric ozone | 49 |
| Dynamic lineage priming is driven via direct enhancer regulation by ERK | 49 |
| Sensory experience remodels genome architecture in neural circuit to drive motor learning | 49 |
| Crystal structure of heliorhodopsin | 49 |
| The Development of Taxonomic Theory Since 1851 | 48 |
| Fix the broken food system in three steps | 48 |
| Upper-plate rigidity determines depth-varying rupture behaviour of megathrust earthquakes | 48 |
| Hypersonic Bose–Einstein condensates in accelerator rings | 48 |
| S-Geranylgeranyl-l-glutathione is a ligand for human B cell-confinement receptor P2RY8 | 48 |
| Hypo-osmotic-like stress underlies general cellular defects of aneuploidy | 48 |
| Genome architecture and stability in the Saccharomyces cerevisiae knockout collection | 48 |
| The amplitude and origin of sea-level variability during the Pliocene epoch | 47 |
| X-ray pumping of the 229Th nuclear clock isomer | 47 |
| A GPR174–CCL21 module imparts sexual dimorphism to humoral immunity | 47 |
| Widespread phytoplankton blooms triggered by 2019–2020 Australian wildfires | 47 |
| Temporal evolution of nitrogen compounds in Swedish precipitation since 1955 | 47 |
| The digitization of organic synthesis | 47 |
| Eat less meat: UN climate-change report calls for change to human diet | 47 |
| Kimberlites reveal 2.5-billion-year evolution of a deep, isolated mantle reservoir | 47 |
| Low-barrier hydrogen bonds in enzyme cooperativity | 47 |
| Structural basis for KCTD-mediated rapid desensitization of GABAB signalling | 46 |
| Collisions between cold molecules in a superconducting magnetic trap | 46 |
| Industrial-era decline in subarctic Atlantic productivity | 46 |
| Deep hydrous mantle reservoir provides evidence for crustal recycling before 3.3 billion years ago | 46 |
| Long-term cyclic persistence in an experimental predator–prey system | 46 |
| A vitamin-C-derived DNA modification catalysed by an algal TET homologue | 46 |
| Chemistry Nobel honours world-changing batteries | 45 |
| One neuron versus deep learning in aftershock prediction | 45 |
| Disaster-zone research needs a code of conduct | 45 |
| Structure and mechanism of mitochondrial proton-translocating transhydrogenase | 45 |
| eIF5B gates the transition from translation initiation to elongation | 45 |
| Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis | 45 |
| A kiwellin disarms the metabolic activity of a secreted fungal virulence factor | 45 |
| Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus | 45 |
| Rethink government with AI | 44 |
| Data sharing and how it can benefit your scientific career | 44 |
| Self-destructing mosquitoes and sterilized rodents: the promise of gene drives | 44 |
| Turbulent convective length scale in planetary cores | 44 |
| A 16-step synthesis of the isoryanodane diterpene (+)-perseanol | 44 |
| A statistical solution to the chaotic, non-hierarchical three-body problem | 44 |
| Real-time vibrations of a carbon nanotube | 44 |
| Self-coalescing flows in microfluidics for pulse-shaped delivery of reagents | 44 |
| Engineering orthogonal signalling pathways reveals the sparse occupancy of sequence space | 44 |
| Female-biased embryonic death from inflammation induced by genomic instability | 44 |
| Feature-selective encoding of substrate vibrations in the forelimb somatosensory cortex | 43 |
| A new Jurassic scansoriopterygid and the loss of membranous wings in theropod dinosaurs | 43 |
| Deep electrical imaging of the ultraslow-spreading Mohns Ridge | 43 |
| Drink more recycled wastewater | 43 |
| Measurability of pressure inside the proton | 42 |
| How AI and neuroscience drive each other forwards | 42 |
| Better methods can’t make up for mediocre theory | 42 |
| The structures and gating mechanism of human calcium homeostasis modulator 2 | 42 |
| Save reefs to rescue all ecosystems | 42 |
| Release from UNC93B1 reinforces the compartmentalized activation of select TLRs | 42 |
| Anthropocene now: influential panel votes to recognize Earth’s new epoch | 42 |
| RB constrains lineage fidelity and multiple stages of tumour progression and metastasis | 42 |
| Depression researchers rethink popular mouse swim tests | 41 |
| Don’t let industry write the rules for AI | 41 |
| The new frontier of gravitational waves | 41 |
| Four steps to extend drone use in research | 41 |
| A 3.8-million-year-old hominin cranium from Woranso-Mille, Ethiopia | 41 |
| Australian gene-editing rules adopt ‘middle ground’ | 41 |
| An actin-based viscoplastic lock ensures progressive body-axis elongation | 41 |
| Treatment of type 2 diabetes with the designer cytokine IC7Fc | 41 |
| Study what makes games addictive | 40 |
| Julia: come for the syntax, stay for the speed | 40 |
| Model and manage the changing geopolitics of energy | 40 |
| Elemental signatures of Australopithecus africanus teeth reveal seasonal dietary stress | 40 |
| A 100-kiloparsec wind feeding the circumgalactic medium of a massive compact galaxy | 40 |
| Metabolic control of BRISC–SHMT2 assembly regulates immune signalling | 40 |
| FHL1 is a major host factor for chikungunya virus infection | 40 |
| Glaciation and Solar Activity since the Fifth Century BC and the Solar Cycle | 39 |
| Rise of Robot Radiologists | 39 |
| Protein-slaying drugs could be the next blockbuster therapies | 39 |
| Why the sexes don’t feel pain the same way | 39 |
| Machine-learning techniques used to accurately predict battery life | 39 |
| Dynamic polymer network points the way to truly recyclable plastics | 39 |
| Collective intercellular communication through ultra-fast hydrodynamic trigger waves | 39 |
| Increased shear in the North Atlantic upper-level jet stream over the past four decades | 39 |
| Absence of amorphous forms when ice is compressed at low temperature | 39 |
| Location-level processes drive the establishment of alien bird populations worldwide | 39 |
| It’s time to talk about ditching statistical significance | 38 |
| Starfish enterprise: finding RNA patterns in single cells | 38 |
| Workflow systems turn raw data into scientific knowledge | 38 |
| Debating the bedrock of climate-change mitigation scenarios | 38 |
| Histone lactylation links metabolism and gene regulation | 38 |
| Credit data generators for data reuse | 38 |
| An evolutionarily stable strategy to colonize spatially extended habitats | 38 |
| Contrasting processes drive ophiuroid phylodiversity across shallow and deep seafloors | 38 |
| Diversity decoupled from ecosystem function and resilience during mass extinction recovery | 38 |
| Multivalent anions as universal latent electron donors | 38 |
| Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity | 38 |
| Date of the Pliocene-Pleistocene Boundary in New Zealand | 37 |
| Marine heatwaves in a changing climate | 37 |
| Japan’s approval of stem-cell treatment for spinal-cord injury concerns scientists | 37 |
| Chemosensory modulation of neural circuits for sodium appetite | 37 |
| Correcting datasets leads to more homogeneous early-twentieth-century sea surface warming | 37 |
| Directionality of dynein is controlled by the angle and length of its stalk | 37 |
| Rethinking impact factors: better ways to judge a journal | 37 |
| Measuring the Berry phase of graphene from wavefront dislocations in Friedel oscillations | 37 |
| Rolling of the jaw is essential for mammalian chewing and tribosphenic molar function | 37 |
| Author Correction: Human placenta has no microbiome but can contain potential pathogens | 37 |
| Seismic velocities of CaSiO3 perovskite can explain LLSVPs in Earth’s lower mantle | 37 |
| Long-period geomagnetic secular variations since 12,000 yr BP | 36 |
| The growth of tea | 36 |
| Cretaceous fossil reveals a new pattern in mammalian middle ear evolution | 36 |
| Women from some under-represented minorities are given too few talks at world’s largest Earth-science conference | 36 |
| Imaging work and dissipation in the quantum Hall state in graphene | 36 |
| Electron pairing in the pseudogap state revealed by shot noise in copper oxide junctions | 36 |
| Vast CO2 release from Australian fires in 2019–2020 constrained by satellite | 36 |
| A new date for Ramapithecus | 35 |
| Superconductivity seen in a non-magnetic nickel oxide | 35 |
| Daytime colour preference in Drosophila depends on the circadian clock and TRP channels | 35 |
| FPR1 is the plague receptor on host immune cells | 35 |
| Publisher Correction: p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis | 35 |
| The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function | 35 |
| Direct limits on the interaction of antiprotons with axion-like dark matter | 35 |
| A powerful cell-protection system prevents cell death by ferroptosis | 34 |
| Revisiting the cold case of cold fusion | 34 |
| The super-cool materials that send heat to space | 34 |
| Author Correction: Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance | 34 |
| Inner ear development in cyclostomes and evolution of the vertebrate semicircular canals | 34 |
| A middle Cambrian arthropod with chelicerae and proto-book gills | 33 |
| Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation | 33 |
| A decline in global CFC-11 emissions during 2018−2019 | 33 |
| Nature’s reach: narrow work has broad impact | 32 |
| A cool accretion disk around the Galactic Centre black hole | 32 |
| The rheology and thermal history of Mars revealed by the orbital evolution of Phobos | 32 |
| Glacial advance relative to volcanic activity since 1500 AD | 31 |
| Precise date for the Laacher See eruption synchronizes the Younger Dryas | 31 |
| Tea | 31 |
| Frequent observations of identical onsets of large and small earthquakes | 31 |
| Where climate cash is flowing and why it’s not enough | 31 |
| Reconstructing the late-accretion history of the Moon | 31 |
| Wnt and TGFβ coordinate growth and patterning to regulate size-dependent behaviour | 31 |
| Foot callus thickness does not trade off protection for tactile sensitivity during walking | 31 |
| Automation: Chemistry shoots for the Moon | 30 |
| How plants perceive salt | 30 |
| Five ways China must cultivate research integrity | 30 |
| Electromagnetic and gravitational responses of photonic Landau levels | 30 |
| Milk of ruminants in ceramic baby bottles from prehistoric child graves | 30 |
| Perfect Andreev reflection due to the Klein paradox in a topological superconducting state | 30 |
| Mapping disparities in education across low- and middle-income countries | 30 |
| Payouts push professors towards predatory journals | 29 |
| Medicinal signalling cells: they work, so use them | 29 |
| New antibiotics target the outer membrane of bacteria | 29 |
| Hydropower dams can help mitigate the global warming impact of wetlands | 29 |
| Imprinting sets the stage for speciation | 29 |
| Concise asymmetric synthesis of (−)-bilobalide | 29 |
| A strongly inhomogeneous superfluid in an iron-based superconductor | 29 |
| Quantifying secondary transport at single-molecule resolution | 29 |
| A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB | 29 |
| Piezoelectric Effect in Poly-γ-methyl-L-glutamate | 28 |
| Infrared variability of the BL lacertae object OJ287 since its outburst in 1983 | 28 |
| The ethics of brain–computer interfaces | 28 |
| The advent and rise of monoclonal antibodies | 28 |
| Antibiotics set to flood Florida’s troubled orange orchards | 28 |
| A fairer way forward for AI in health care | 28 |
| Five innovative ways to use 3D printing in the laboratory | 28 |
| Earth’s magnetic field is acting up and geologists don’t know why | 28 |
| Interacting Floquet polaritons | 28 |
| Neurocranial development of the coelacanth and the evolution of the sarcopterygian head | 28 |
| Author Correction: Single-cell transcriptomic analysis of Alzheimer’s disease | 28 |
| An Œstrogenic Substance in Pollen-grains of Date Palm Tree Phœnix dactylifera L., Palmæ | 27 |
| Dry years in south-east England since 1698 | 27 |
| The influence of solar forcing trends on global mean temperature since 1861 | 27 |
| Hunting for New Drugs with AI | 27 |
| A DIY approach to automating your lab | 27 |
| Quantum gold rush: the private funding pouring into quantum start-ups | 27 |
| Self-formed bedrock waterfalls | 27 |
| Elastic colloidal monopoles and reconfigurable self-assembly in liquid crystals | 27 |
| Magnetic monopole noise | 27 |
| A warped disk around an infant protostar | 27 |