Proceedings of the National Academy of Sciences of the United States o

Papers
(The TQCC of Proceedings of the National Academy of Sciences of the United States o is 88. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-06-01 to 2023-06-01.)
ArticleCitations
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.32887
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.5094
Measuring the thickness of the human cerebral cortex from magnetic resonance images4200
Amino acid substitution matrices from protein blocks.4068
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.3939
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa3856
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.3404
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma3368
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib3355
Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.3047
Histone H3K27ac separates active from poised enhancers and predicts developmental state2976
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI2714
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins2701
Prediction of protein antigenic determinants from amino acid sequences.2379
Predicting human resting-state functional connectivity from structural connectivity2326
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies2282
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade2151
SHED: Stem cells from human exfoliated deciduous teeth1962
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.1859
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.1824
Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.1700
A multidrug resistance transporter from human MCF-7 breast cancer cells1666
Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.1625
A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR1581
Rice yields decline with higher night temperature from global warming1566
Contributions to accelerating atmospheric CO 2 growth from economic activity, carbon intensity, and efficiency of natural sinks1559
Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli.1556
Discovering governing equations from data by sparse identification of nonlinear dynamical systems1543
From tropics to tundra: Global convergence in plant functioning1534
Breast cancer classification and prognosis based on gene expression profiles from a population-based study1463
Materials become insensitive to flaws at nanoscale: Lessons from nature1452
Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.1447
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS1434
Private traits and attributes are predictable from digital records of human behavior1429
Cancerous stem cells can arise from pediatric brain tumors1410
Multiple evolutionary origins of the fungus causing Panama disease of banana: Concordant evidence from nuclear and mitochondrial gene genealogies1405
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction1368
Interaction ruling animal collective behavior depends on topological rather than metric distance: Evidence from a field study1354
Formation of Bimolecular Membranes from Lipid Monolayers and a Study of Their Electrical Properties1341
Sea level and global ice volumes from the Last Glacial Maximum to the Holocene1327
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.1326
rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data1322
High-quality draft assemblies of mammalian genomes from massively parallel sequence data1314
Neural mechanisms of empathy in humans: A relay from neural systems for imitation to limbic areas1307
A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.1286
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes1273
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer1236
A DNA transfection system for generation of influenza A virus from eight plasmids1236
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.1211
Rapid morphological radiation and convergence among races of the butterfly Heliconius erato inferred from patterns of mitochondrial DNA evolution.1191
Predicting DNA duplex stability from the base sequence.1180
Aptamers evolved from live cells as effective molecular probes for cancer study1176
Bax directly induces release of cytochrome c from isolated mitochondria1172
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling1169
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy1168
Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels1163
Situating the default-mode network along a principal gradient of macroscale cortical organization1151
Crop pollination from native bees at risk from agricultural intensification1146
Evaluation of methods for detecting recombination from DNA sequences: Computer simulations1121
From time series to complex networks: The visibility graph1109
Dystrophin protects the sarcolemma from stresses developed during muscle contraction.1091
Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes1086
Are we in the midst of the sixth mass extinction? A view from the world of amphibians1082
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes1075
Generation of influenza A viruses entirely from cloned cDNAs1060
Evidence on the impact of sustained exposure to air pollution on life expectancy from China’s Huai River policy1053
Identification of Methylated Nucleosides in Messenger RNA from Novikoff Hepatoma Cells1050
Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinases1049
Growth in emission transfers via international trade from 1990 to 20081048
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal1038
Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-Å resolution1026
A novel iron-regulated metal transporter from plants identified by functional expression in yeast.1016
Derivation of pluripotent stem cells from cultured human primordial germ cells1009
Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases.987
An amplified sensitivity arising from covalent modification in biological systems.950
Drivers of improved PM 2.5 air quality in China from 2013 to 2017940
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.938
Persistent cannabis users show neuropsychological decline from childhood to midlife936
Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments935
Amplified RNA synthesized from limited quantities of heterogeneous cDNA.925
Preparative and analytical purification of DNA from agarose.912
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.903
Persistent sulfate formation from London Fog to Chinese haze901
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease900
Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.894
Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas893
From micro to nano contacts in biological attachment devices885
Growth factors from murine sarcoma virus-transformed cells.876
Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.873
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics870
Strong interlayer coupling in van der Waals heterostructures built from single-layer chalcogenides868
Lignin-degrading enzyme from Phanerochaete chrysosporium : Purification, characterization, and catalytic properties of a unique H 2 O 868
Anthropogenic warming has increased drought risk in California861
Eye contact detection in humans from birth856
DNA sequence-dependent deformability deduced from protein–DNA crystal complexes849
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method844
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus840
Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems840
Ferroptosis as a target for protection against cardiomyopathy840
Tumor necrosis factor alpha inhibits signaling from the insulin receptor.836
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells835
Analysis of 81 genes from 64 plastid genomes resolves relationships in angiosperms and identifies genome-scale evolutionary patterns834
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa816
Distinguishing influence-based contagion from homophily-driven diffusion in dynamic networks815
Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood814
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.808
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation804
Anthropogenic drivers of 2013–2017 trends in summer surface ozone in China798
Normal genetically mosaic mice produced from malignant teratocarcinoma cells.790
A 40-Hz auditory potential recorded from the human scalp.788
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells784
Net energy of cellulosic ethanol from switchgrass784
Lifespan and reproduction in Drosophila : New insights from nutritional geometry778
Generation of human induced pluripotent stem cells from dermal fibroblasts778
A distinct lineage of influenza A virus from bats768
Derivation of midbrain dopamine neurons from human embryonic stem cells766
Reactive intermediates revealed in secondary organic aerosol formation from isoprene760
In vitro cultivation of human islets from expanded ductal tissue755
PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates.735
Free energy reconstruction from nonequilibrium single-molecule pulling experiments731
PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription730
In vivo evidence that erythropoietin protects neurons from ischemic damage720
Cytochrome c release from mitochondria proceeds by a two-step process720
A2A adenosine receptor protects tumors from antitumor T cells719
Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells.717
Spontaneous assembly of double-stranded helicates from oligobipyridine ligands and copper(I) cations: structure of an inorganic double helix.717
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both 716
Endothelial cells derived from human embryonic stem cells714
Hematopoietic potential of stem cells isolated from murine skeletal muscle714
Transplantation of living nuclei from blastula cells into enucleated frogs’ eggs713
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.708
Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells.703
Leukotriene C: a slow-reacting substance from murine mastocytoma cells.703
Three-dimensional Reconstruction from Radiographs and Electron Micrographs: Application of Convolutions instead of Fourier Transforms698
Nitrososphaera viennensis , an ammonia oxidizing archaeon from soil694
Biomass use, production, feed efficiencies, and greenhouse gas emissions from global livestock systems692
Consistent blind protein structure generation from NMR chemical shift data691
Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.689
Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase)686
Hematopoietic colony-forming cells derived from human embryonic stem cells686
Silicatein filaments and subunits from a marine sponge direct the polymerization of silica and silicones in vitro684
Efficient Translation of Tobacco Mosaic Virus RNA and Rabbit Globin 9S RNA in a Cell-Free System from Commercial Wheat Germ679
Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral678
Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site.677
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.675
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein.675
beta-Glucuronidase from Escherichia coli as a gene-fusion marker.671
Structure of the reaction center from Rhodobacter sphaeroides R-26: the cofactors.670
Patterns of damage in genomic DNA sequences from a Neandertal668
Cell-type-specific isolation of ribosome-associated mRNA from complex tissues664
Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration659
Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril653
Whole genome amplification from a single cell: implications for genetic analysis.649
Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm647
Pungent products from garlic activate the sensory ion channel TRPA1647
Discovery of drug mode of action and drug repositioning from transcriptional responses643
A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila642
Constructing the equilibrium ensemble of folding pathways from short off-equilibrium simulations641
Definitions, methods, and applications in interpretable machine learning639
Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.635
THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM633
The tac promoter: a functional hybrid derived from the trp and lac promoters.632
Alkaline polymer electrolyte fuel cells completely free from noble metal catalysts630
Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis622
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.620
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands615
Culture of hormone-dependent functional epithelial cells from rat thyroids.610
Genomic correlates of clinical outcome in advanced prostate cancer606
Natural capital and ecosystem services informing decisions: From promise to practice603
Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.603
Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes.595
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase594
A black body absorber from vertically aligned single-walled carbon nanotubes592
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia592
A detergent-free method for purifying caveolae membrane from tissue culture cells.591
Phytochelatins, a class of heavy-metal-binding peptides from plants, are functionally analogous to metallothioneins589
Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models588
Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited584
Re-evaluation of forest biomass carbon stocks and lessons from the world's most carbon-dense forests580
Evolutionary relationship of archaebacteria, eubacteria, and eukaryotes inferred from phylogenetic trees of duplicated genes.579
Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse.579
Massive nitrogen loss from the Benguela upwelling system through anaerobic ammonium oxidation578
Non-blinking and photostable upconverted luminescence from single lanthanide-doped nanocrystals576
Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.572
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA572
Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid.569
Brain homogenates from human tauopathies induce tau inclusions in mouse brain568
Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding.568
Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow565
Acoustic separation of circulating tumor cells563
pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.562
Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species.561
A moderately thermophilic ammonia-oxidizing crenarchaeote from a hot spring560
Drought- and salt-tolerant plants result from overexpression of the AVP1 H + -pump559
Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.557
Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences557
Photoinduced electron transfer from semiconductor quantum dots to metal oxide nanoparticles557
Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress556
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages554
Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice552
Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/ scid mice551
Species-specific polyamines from diatoms control silica morphology545
Single virus detection from the reactive shift of a whispering-gallery mode544
Separation of human breast cancer cells from blood by differential dielectric affinity.544
New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.542
Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes.540
Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations540
Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation539
Identification and characterization of a ouabain-like compound from human plasma.538
Electroencephalogram signatures of loss and recovery of consciousness from propofol536
The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria534
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis534
Ecosystem services: From theory to implementation534
Characterization of a gamma-carboxyglutamic acid-containing protein from bone.534
A simple model for calculating the kinetics of protein folding from three-dimensional structures532
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.532
Rescuing US biomedical research from its systemic flaws531
Evidence for capillarity contributions to gecko adhesion from single spatula nanomechanical measurements531
Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis530
The violaxanthin cycle protects plants from photooxidative damage by more than one mechanism529
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity528
Efficient generation of retinal progenitor cells from human embryonic stem cells527
Isolation of exosomes from whole blood by integrating acoustics and microfluidics525
Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency524
In vitrocartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis522
Cytokine therapeutics: lessons from interferonalpha.522
Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system.521
Neural deficits in children with dyslexia ameliorated by behavioral remediation: Evidence from functional MRI519
Hydrological droughts in the 21st century, hotspots and uncertainties from a global multimodel ensemble experiment517
Fibril in senile systemic amyloidosis is derived from normal transthyretin.514
Calculation of absolute protein–ligand binding free energy from computer simulations514
Four decades of Antarctic Ice Sheet mass balance from 1979–2017512
Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation.512
Severe haze in northern China: A synergy of anthropogenic emissions and atmospheric processes512
On the actions that one nerve cell can have on another: Distinguishing “drivers” from “modulators”511
Genetic manipulation of lignin reduces recalcitrance and improves ethanol production from switchgrass511
Formation of native prions from minimal components in vitro510
Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages508
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake508
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer507
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids507
Derivation of force fields for molecular mechanics and dynamics from ab initio energy surfaces506
Cre-lox-regulated conditional RNA interference from transgenes505
AN ESTIMATE OF THE MUTATIONAL DAMAGE IN MAN FROM DATA ON CONSANGUINEOUS MARRIAGES505
Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons505
Predicting cancer outcomes from histology and genomics using convolutional networks503
Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature500
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles499
The hippocampal formation participates in novel picture encoding: evidence from functional magnetic resonance imaging.498
New technologies reduce greenhouse gas emissions from nitrogenous fertilizer in China498
Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging497
Evolution of the vacuolar H+-ATPase: implications for the origin of eukaryotes.495
Time-varying functional network information extracted from brief instances of spontaneous brain activity493
Recombinant vesicular stomatitis viruses from DNA.493
Greater focus needed on methane leakage from natural gas infrastructure492
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry492
Indirect land-use changes can overcome carbon savings from biofuels in Brazil491
RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12491
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors488
Mechanism of oligonucleotide release from cationic liposomes.488
Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters488
Dissecting biological “dark matter” with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth487
Perspectives on archaeal diversity, thermophily and monophyly from environmental rRNA sequences.486
The deepest divergences in land plants inferred from phylogenomic evidence486
Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of developmen486
Allometric scaling of metabolic rate from molecules and mitochondria to cells and mammals485
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins484
Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode.483
Shotgun identification of protein modifications from protein complexes and lens tissue483
9,400 years of cosmic radiation and solar activity from ice cores and tree rings479
α-KETO ACID DEHYDROGENASE COMPLEXES, X. REGULATION OF THE ACTIVITY OF THE PYRUVATE DEHYDROGENASE COMPLEX FROM BEEF KIDNEY MITOCHONDRIA BY PHOSPHORYLATION AND DEPHOSPHORYLATION479
The structure of the chromophore within DsRed, a red fluorescent protein from coral477
Turning back from the brink: Detecting an impending regime shift in time to avert it475
Green-up dates in the Tibetan Plateau have continuously advanced from 1982 to 2011475
Substantial nitrogen acquisition by arbuscular mycorrhizal fungi from organic material has implications for N cycling474
A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.473
A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells.471
Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage.471
An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization.470
Electrical transport along bacterial nanowires from Shewanella oneidensis MR-1468
Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions467
Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study467
Designing payments for ecosystem services: Lessons from previous experience with incentive-based mechanisms466
Differential effects of prostaglandin derived from ω-6 and ω-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion466
Darwin's abominable mystery: Insights from a supertree of the angiosperms465
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments464
From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression464
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.464
Self-recognition in helicate self-assembly: spontaneous formation of helical metal complexes from mixtures of ligands and metal ions.463
From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor461
Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis460
Humid tropical forest clearing from 2000 to 2005 quantified by using multitemporal and multiresolution remotely sensed data460
Diglyceride lipase: a pathway for arachidonate release from human platelets.460
Parathyroid hormone-related protein purified from a human lung cancer cell line.460
Crystal structure of core streptavidin determined from multiwavelength anomalous diffraction of synchrotron radiation.458
Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease458
Carbon emissions from tropical deforestation and regrowth based on satellite observations for the 1980s and 1990s458
Protein structure determination from NMR chemical shifts457
Gene RB cloned from Solanum bulbocastanum confers broad spectrum resistance to potato late blight455
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling454
Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light.453
Annually reoccurring bacterial communities are predictable from ocean conditions453
Beyond superquenching: Hyper-efficient energy transfer from conjugated polymers to gold nanoparticles449
Six-rowed barley originated from a mutation in a homeodomain-leucine zipper I-class homeobox gene449
Global threat to agriculture from invasive species448
Isolation of an iron-molybdenum cofactor from nitrogenase446
Nitrous oxide emission from denitrification in stream and river networks446
Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment446
Patterns of spread in biological invasions dominated by long-distance jump dispersal: Insights from Argentine ants445
Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.443
A carbonic anhydrase from the nacreous layer in oyster pearls.443
Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs443
Improved evolutionary optimization from genetically adaptive multimethod search443
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.442
Receptor-mediated endocytosis: insights from the lipoprotein receptor system.442
Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.440
A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization.440
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors439
Dissociation of human mid-dorsolateral from posterior dorsolateral frontal cortex in memory processing.439
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.439
Generation of pluripotent stem cells from patients with type 1 diabetes439
Apoptosis in heart failure: Release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy438
Structure of the reaction center from Rhodobacter sphaeroides R-26: the protein subunits.437
RECONSTITUTION OF ACTIVE TOBACCO MOSAIC VIRUS FROM ITS INACTIVE PROTEIN AND NUCLEIC ACID COMPONENTS437
Molecular and functional analysis of the TOL plasmid pWWO from Pseudomonas putida and cloning of genes for the entire regulated aromatic ring meta cleavage pathway.437
Tigers and their prey: Predicting carnivore densities from prey abundance434
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig433
Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT 3 gene432
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas.432
Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization.430
DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID BY AN ENZYME FROM ESCHERICHIA COLI430
PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM429
X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.429
Elicitor-stimulated ion fluxes and O 2 from the oxidative burst are essential components in triggering defense gene activation and phytoalex428
Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus428
Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure.427
Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins.426
Date of the monocot-dicot divergence estimated from chloroplast DNA sequence data.425
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles425
Starch grain and phytolith evidence for early ninth millennium B.P. maize from the Central Balsas River Valley, Mexico423
Toward controlling gene expression at will: Specific regulation of the erbB - 2 / HER - 2423
Regulation of the immune system by biodiversity from the natural environment: An ecosystem service essential to health423
Gender differences in COVID-19 attitudes and behavior: Panel evidence from eight countries423
Gravity-regulated differential auxin transport from columella to lateral root cap cells421
Effective amplification of long targets from cloned inserts and human genomic DNA.421
Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures.421
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee421
endo-beta-N-acetylglucosaminidase F: endoglycosidase from Flavobacterium meningosepticum that cleaves both high-mannose and complex glycoproteins.421
Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence.419
Reproductive protein protects functionally sterile honey bee workers from oxidative stress417
Generating a synthetic genome by whole genome assembly: φX174 bacteriophage from synthetic oligonucleotides416
Effects of anthropogenic emissions on aerosol formation from isoprene and monoterpenes in the southeastern United States416
A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.416
Crystal structure of cytochrome P450 14α-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors416
Expression cloning of an ATP receptor from mouse neuroblastoma cells.415
Cultivation of an obligate acidophilic ammonia oxidizer from a nitrifying acid soil415
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer414
Identification of tissue-specific cell death using methylation patterns of circulating DNA414
Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.413
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.413
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia412
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans412
Isolation of a heparan sulfate-containing proteoglycan from basement membrane.411
The molecular machinery for secretion is conserved from yeast to neurons.411
Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells.411
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.408
An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues407
Robust prediction of individual creative ability from brain functional connectivity407
From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells406
Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques406
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.405
Transfer of photosynthesis genes to and from Prochlorococcus viruses405
Structure of membrane-bound α-synuclein from site-directed spin labeling and computational refinement404
CTR1 phosphorylates the central regulator EIN2 to control ethylene hormone signaling from the ER membrane to the nucleus in Arabidopsis404
Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma404
Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis403
Reaction coordinates and rates from transition paths402
New evidence on the impact of sustained exposure to air pollution on life expectancy from China’s Huai River Policy401
Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production.400
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.399
Three-dimensional manipulation of single cells using surface acoustic waves399
Spring temperature change and its implication in the change of vegetation growth in North America from 1982 to 2006397
Stomatocyte–discocyte–echinocyte sequence of the human red blood cell: Evidence for the bilayer– couple hypothesis from membrane mechanics397
Function and evolution of a minimal plastid genome from a nonphotosynthetic parasitic plant.397
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells396
Why did modern human populations disperse from Africa ca. 60,000 years ago? A new model394
Genesis of hexavalent chromium from natural sources in soil and groundwater394
Propagation and recovery of intact, infectious Epstein–Barr virus from prokaryotic to human cells394
Phosphorylation of nucleic acid by an enzyme from T4 bacteriophage-infected Escherichia coli.393
DNA analysis of an early modern human from Tianyuan Cave, China393
Reconciling modern machine-learning practice and the classical bias–variance trade-off393
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases393
Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes390
Conscious recollection and the human hippocampal formation: evidence from positron emission tomography.390
Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999390
Superfamily phenomena and motifs of networks induced from time series388
Elevated gene expression levels distinguish human from non-human primate brains388
Speech comprehension is correlated with temporal response patterns recorded from auditory cortex388
Isolation of a Calcium-Sequestering Protein from Sarcoplasmic Reticulum387
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells386
Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus.386
Disappearance of insectivorous birds from tropical forest fragments386
Microsporidia are related to Fungi: Evidence from the largest subunit of RNA polymerase II and other proteins385
Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK385
Identification of a functional transposase of the Tol2 element, an Ac -like element from the Japanese medaka fish, and its transposition i383
Map-based isolation of the leaf rust disease resistance gene Lr10 from the hexaploid wheat ( Triticum aestivum L.) genome382
Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.382
Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease.382
Projecting hospital utilization during the COVID-19 outbreaks in the United States382
MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia382
Dissociation of tissue uptake of cholesterol ester from that of apoprotein A-I of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal, and gonad.381
Isolation and Characterization of Calcifying Matrix Vesicles from Epiphyseal Cartilage381
Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury380
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist379
H 2 -rich fluids from serpentinization: Geochemical and biotic implications379
Tempo and mode of evolution revealed from molecular phylogenies.379
Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence378
β-Catenin mutations in cell lines established from human colorectal cancers378
Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community377
Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation.377
Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device377
TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8 + T cell exhaustion377
Impact of international travel and border control measures on the global spread of the novel 2019 coronavirus outbreak376
Efficient recovery of infectious vesicular stomatitis virus entirely from cDNA clones.376
Mice cloned from embryonic stem cells376
PICKLE is a CHD3 chromatin-remodeling factor that regulates the transition from embryonic to vegetative development in Arabidopsis375
Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication375
Overexpression of a zinc-finger protein gene from rice confers tolerance to cold, dehydration, and salt stress in transgenic tobacco374
A highly efficient and robust cell-free protein synthesis system prepared from wheat embryos: Plants apparently contain a suicide system directed at ribosomes374
Animals and fungi are each other's closest relatives: congruent evidence from multiple proteins.372
De novo generation of neuronal cells from the adult mouse brain.372
PsbS-dependent enhancement of feedback de-excitation protects photosystem II from photoinhibition372
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions371
Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants.371
A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering370
Derivation of induced pluripotent stem cells from pig somatic cells370
Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.369
A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.369
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling369
High throughput protein fold identification by using experimental constraints derived from intramolecular cross-links and mass spectrometry368
Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons.368
Age of Jupiter inferred from the distinct genetics and formation times of meteorites366
Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice365
Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract365
A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells365
Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity364
A peptidoglycan recognition protein in innate immunity conserved from insects to humans364
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy364
Solar-driven, highly sustained splitting of seawater into hydrogen and oxygen fuels364
An in vitro polysome display system for identifying ligands from very large peptide libraries.364
Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli.363
Forty-six years of Greenland Ice Sheet mass balance from 1972 to 2018363
RNA transcription modulates phase transition-driven nuclear body assembly362
Measuring actual learning versus feeling of learning in response to being actively engaged in the classroom362
Inactivation of the mitogen-activated protein kinase Mps1 from the rice blast fungus prevents penetration of host cells but allows activation of plant defense responses360
Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence360
Endogenous cellulases in animals: Isolation of β-1,4-endoglucanase genes from two species of plant-parasitic cyst nematodes359
Evidence on the emergence of the brain's default network from 2-week-old to 2-year-old healthy pediatric subjects359
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.359
Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA.358
Trade-offs and synergies between carbon storage and livelihood benefits from forest commons358
Elucidating secondary organic aerosol from diesel and gasoline vehicles through detailed characterization of organic carbon emissions358
Revised estimates of human cochlear tuning from otoacoustic and behavioral measurements357
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.357
Science audiences, misinformation, and fake news357
Isolation and one-step preparation of A2E and iso -A2E, fluorophores from human retinal pigment epithelium357
A NERVE GROWTH-STIMULATING FACTOR ISOLATED FROM SARCOM AS 37 AND 180356
Zika virus cell tropism in the developing human brain and inhibition by azithromycin356
Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo.355
The implications of silent transmission for the control of COVID-19 outbreaks355
Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory355
Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression354
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia354
Meta-analysis of field experiments shows no change in racial discrimination in hiring over time354
Mapping amorphous calcium phosphate transformation into crystalline mineral from the cell to the bone in zebrafish fin rays354
Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA.353
Effects of national ecological restoration projects on carbon sequestration in China from 2001 to 2010353
Six cloned calves produced from adult fibroblast cells after long-term culture352
Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host352
Twentieth century climate change: Evidence from small glaciers351
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects351
Risk of being killed by police use of force in the United States by age, race–ethnicity, and sex351
NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes350
Sequence information can be obtained from single DNA molecules350
Components of verbal working memory: Evidence from neuroimaging349
The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle349
High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors.348
Insights on linking forests, trees, and people from the air, on the ground, and in the laboratory348
Folding of the DNA double helix in chromatin-like structures from simian virus 40.347
Fragilities of liquids predicted from the random first order transition theory of glasses347
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum347
Quantifying the influence of global warming on unprecedented extreme climate events347
Refined crystal structure of DsRed, a red fluorescent protein from coral, at 2.0-Å resolution346
Effects of fossil fuel and total anthropogenic emission removal on public health and climate346
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea ( Coprinus cinereus )346
Rainfall-induced carbon dioxide pulses result from sequential resuscitation of phylogenetically clustered microbial groups346
Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice346
Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids.346
Long-term culture of B lymphocytes and their precursors from murine bone marrow.345
Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin.344
Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons.343
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models342
Expanded metabolic versatility of ubiquitous nitrite-oxidizing bacteria from the genus Nitrospira341
82,000-year-old shell beads from North Africa and implications for the origins of modern human behavior341
Interphase chromosomes in Arabidopsis are organized as well defined chromocenters from which euchromatin loops emanate341
Air pollutant emissions from Chinese households: A major and underappreciated ambient pollution source340
Myofibroblasts differentiate from fibroblasts when plated at low density.340
Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in340
Economic and energetic analysis of capturing CO 2 from ambient air339
Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes.339
Full atomistic reaction mechanism with kinetics for CO reduction on Cu(100) from ab initio molecular dynamics free-energy calculations at 298 K339
Gene expression from plasmids containing the araBAD promoter at subsaturating inducer concentrations represents mixed populations339
A small element from the Mason-Pfizer monkey virusgenome makes human immunodeficiency virus type 1 expression and replicationRev-independent.338
EXECUTER1- and EXECUTER2-dependent transfer of stress-related signals from the plastid to the nucleus of Arabidopsis thaliana338
Atmospheric nitrogen deposition promotes carbon loss from peat bogs338
Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues338
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.338
Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase337
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum337
Emulating biology: Building nanostructures from the bottom up337
Neurons containing beta-endorphin in rat brain exist separately from those containing enkephalin: immunocytochemical studies.336
Working-memory capacity protects model-based learning from stress336
Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling335
Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness335
Two-dimensional polyaniline (C 3 N) from carbonized organic single crystals in solid state335
Assessment of individual radionuclide distributions from the Fukushima nuclear accident covering central-east Japan334
Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies334
Dissecting the THz spectrum of liquid water from first principles via correlations in time and space334
Multiple health and environmental impacts of foods334
Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.333
Singlet oxygen mediated iron-based Fenton-like catalysis under nanoconfinement333
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin332
Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Förster resonance energy transfer imaging332
Design and characterization of synthetic fungal-bacterial consortia for direct production of isobutanol from cellulosic biomass332
Ruminococcus gnavus , a member of the human gut microbiome associated with Crohn’s disease, produces an inflammatory polysaccharide332
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells331
Shifting carbon flow from roots into associated microbial communities in response to elevated atmospheric CO 2331
A general framework for quantitatively assessing ecological stochasticity331
Mediation of tubuloglomerular feedback by adenosine: Evidence from mice lacking adenosine 1 receptors331
Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poison.330
HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance330
A continuum of genetic divergence from sympatric host races to species in the pea aphid complex329
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.329
The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone.328
From wild animals to domestic pets, an evolutionary view of domestication328
Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23).328
X-ray structure of a vanadium-containing enzyme: chloroperoxidase from the fungus Curvularia inaequalis.328
Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis328
Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle328
Superficial white matter fiber systems impede detection of long-range cortical connections in diffusion MR tractography328
Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it.327
Phosphate transporters from the higher plant Arabidopsis thaliana.327
Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin.326
Cancer stem cells from colorectal cancer-derived cell lines326
Global rise in emerging alien species results from increased accessibility of new source pools326
Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.326
Wheat grain hardness results from highly conserved mutations in the friabilin components puroindoline a and b326
Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels326
Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.326
Rapid depletion of genotypes with fast growth and bold personality traits from harvested fish populations326
Isolation of a new herpesvirus from human CD4+ T cells.325
Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix.325
Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice324
Seed plant phylogeny inferred from all three plant genomes: Monophyly of extant gymnosperms and origin of Gnetales from conifers324
Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells.324
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product.324
Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo.324
Human immune disorder arising from mutation of the α chain of the interleukin-2 receptor323
Twenty-five years of mTOR: Uncovering the link from nutrients to growth322
AtPCS1, a phytochelatin synthase from Arabidopsis : Isolation and in vitro reconstitution321
An amyloid-forming peptide from the yeast prion Sup35 reveals a dehydrated β-sheet structure for amyloid321
Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.321
Microbiome interactions shape host fitness321
Periplasmic superoxide dismutase protectsSalmonellafrom products of phagocyte NADPH-oxidase and nitric oxide synthase320
Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle.319
Atoms and molecules in cavities, from weak to strong coupling in quantum-electrodynamics (QED) chemistry319
A family of fatty acid transporters conserved from mycobacterium to man318
Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures318
Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei317
Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse.316
Selective release of glutamate from cerebellar granule cells differentiating in culture316
Early farmers from across Europe directly descended from Neolithic Aegeans316
Expression cloning of a high-affinity melatonin receptor from Xenopus dermal melanophores.315
Reduced default mode network functional connectivity in patients with recurrent major depressive disorder315
Inferring social ties from geographic coincidences315
Chlorophyll a oxygenase ( CAO ) is involved in chlorophyll b formation from chlorophyll a315
Fundamental patterns underlying gene expression profiles: Simplicity from complexity314
Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources.314
Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica313
ESTABLISHMENT OF FUNCTIONAL CLONAL LINES OF NEURONS FROM MOUSE NEUROBLASTOMA313
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors313
N-degron and C-degron pathways of protein degradation313
Refactoring the nitrogen fixation gene cluster from Klebsiella oxytoca313
Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses311
Mitochondrial DNA sequences in single hairs from a southern African population.311
Gene transfer with subsequent removal of the selection gene from the host genome.310
Ultrafast dynamics of protein collapse from single-molecule photon statistics310
Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens309
Rhs proteins from diverse bacteria mediate intercellular competition308
A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli.308
Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases308
Residential green space in childhood is associated with lower risk of psychiatric disorders from adolescence into adulthood308
The urgency of the development of CO 2 capture from ambient air307
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells306
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures305
Molecular identification of bacteria in bronchoalveolar lavage fluid from children with cystic fibrosis305
Structure and function of E. coli ribosomes. V. Reconstitution of functionally active 30S ribosomal particles from RNA and proteins.305
Chromatographically isolated CD63 + CD81 + extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments afte305
Evolution of antifreeze glycoprotein gene from a trypsinogen gene in Antarctic notothenioid fish305
The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties304
Synthesis of C 5 -dicarboxylic acids from C 2 -units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway304
In vivodynamics of antigen-specific regulatory T cells not predicted from behaviorin vitro304
β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from G s to G i303
Varroa destructorfeeds primarily on honey bee fat body tissue and not hemolymph303
Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury303
A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.303
Inferring individual rules from collective behavior302
Formation of a crystal nucleus from liquid302
Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis301
Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979.301
Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.301
ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells.301
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system300
Reactivity of the HIV-1 nucleocapsid protein p7 zinc finger domains from the perspective of density-functional theory299
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells299
Synthesis of three advanced biofuels from ionic liquid-pretreated switchgrass using engineered Escherichia coli299
Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties299
Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.299
Mind wandering away from pain dynamically engages antinociceptive and default mode brain networks299
The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.298
Details of the evolutionary history from invertebratesto vertebrates, as deduced from the sequences of 18S rDNA.298
“Global” cell replacement is feasible via neural stem cell transplantation: Evidence from the dysmyelinated shiverer mouse brain298
ADP dissociation from actomyosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate muscle.298
Terpenoid biosynthesis from 1-deoxy- d -xylulose in higher plants by intramolecular skeletal rearrangement297
Human coronaviruses OC43 and HKU1 bind to 9- O -acetylated sialic acids via a conserved receptor-binding site in spike protein domain A297
Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.297
Fighting misinformation on social media using crowdsourced judgments of news source quality297
Squalamine: an aminosterol antibiotic from the shark.297
Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart296
Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci.296
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.296
Menopause accelerates biological aging296
Adoptively transferred effector cells derived from naïve rather than central memory CD8 + T cells mediate superior antitumor immunity296
Isolation of fetal DNA from nucleated erythrocytes in maternal blood.296
Distance-based protein folding powered by deep learning296
Neuroglobin protects the brain from experimental stroke in vivo295
Cosmic Rays from Super-Novae295
Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.295
BCG vaccine protection from severe coronavirus disease 2019 (COVID-19)295
Carbohydrate-like composition of submicron atmospheric particles and their production from ocean bubble bursting295
Solar absorption by elemental and brown carbon determined from spectral observations295
Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.294
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA294
Climate change mitigation potential of carbon capture and utilization in the chemical industry294
Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-γ production from activated B cells294
Controlling cell–cell interactions using surface acoustic waves293
Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate293
Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2293
Antibacterial peptides from pig intestine: isolation of a mammalian cecropin.292
Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal292
Solar influence on climate during the past millennium: Results from transient simulations with the NCAR Climate System Model291
Neural mechanisms of transient neocortical beta rhythms: Converging evidence from humans, computational modeling, monkeys, and mice291
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain291
Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.291
An oleate 12-hydroxylase from Ricinus communis L. is a fatty acyl desaturase homolog.290
Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of d -1290
Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors289
Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice.289
Ice sheet contributions to future sea-level rise from structured expert judgment289
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice.289
Megafauna and ecosystem function from the Pleistocene to the Anthropocene289
Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma289
National burden of disease in India from indoor air pollution289
Global ensemble projections reveal trophic amplification of ocean biomass declines with climate change288
Functional and evolutionary genomics of Mycobacterium tuberculosis : Insights from genomic deletions in 100 strains285
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei285
Nucleotide sequence of the gene for a fibronectin-binding protein from Staphylococcus aureus: use of this peptide sequence in the synthesis of biologically active peptides.285
No ·NO from NO synthase285
Induction of Bradyrhizobium japonicum common nod genes by isoflavones isolated from Glycine max285
Efficient solar-to-fuels production from a hybrid microbial–water-splitting catalyst system284
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells284
Transcriptome dynamics of Deinococcus radiodurans recovering from ionizing radiation284
Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas.284
Production of extremely low volatile organic compounds from biogenic emissions: Measured yields and atmospheric implications284
Converting enzyme-independent release of tumor necrosis factor α and IL-1β from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3284
Cellulosic ethanol production from AFEX-treated corn stover using Saccharomyces cerevisiae 424A(LNH-ST)284
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1.282
Bootstrapping cluster analysis: Assessing the reliability of conclusions from microarray experiments282
Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.282
From perception to pleasure: Music and its neural substrates282
Structural and functional recovery from early monocular deprivation in adult rats282
Purification of a calmodulin-binding protein from chicken gizzard that interacts with F-actin.281
Optimal protein-folding codes from spin-glass theory.281
Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates281
Predicting political elections from rapid and unreflective face judgments281
Effect of Visible Light on the Recovery of Streptomyces Griseus Conidia from Ultra-violet Irradiation Injury280
Equilibrium distributions of microsatellite repeat length resulting from a balance between slippage events and point mutations280
The evolution and genomic basis of beetle diversity280
Femtosecond spectroscopy of electron transfer in the reaction center of the photosynthetic bacterium Rhodopseudomonas sphaeroides R-26: Direct electron transfer from the280
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.280
BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis280
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity279
Global warming has increased global economic inequality279
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin279
P2X4: an ATP-activated ionotropic receptor cloned from rat brain.279
Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages279
DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires279
Committed carbon emissions, deforestation, and community land conversion from oil palm plantation expansion in West Kalimantan, Indonesia278
Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration.278
Role of forest regrowth in global carbon sink dynamics278
Virus–virus interactions impact the population dynamics of influenza and the common cold278
Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine.278
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA278
Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir278
Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.278
Amyloid protein SAA is associated with high density lipoprotein from human serum.278
Simian Virus 40 DNA Sequences in DNA of Healthy Adult Mice Derived from Preimplantation Blastocysts Injected with Viral DNA277
Gyrification from constrained cortical expansion277
Cucumber ( Cucumis sativus ) and melon ( C. melo ) have numerous wild relatives in Asia and Australia, and the sister species of melon is 277
Nerve Growth Factor from Mouse Submaxillary Gland: Amino Acid Sequence276
Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys276
Machine learning-assisted directed protein evolution with combinatorial libraries276
Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments276
Inequity in consumption of goods and services adds to racial–ethnic disparities in air pollution exposure276
Cadmium resistance from Staphylococcus aureus plasmid pI258 cadA gene results from a cadmium-efflux ATPase.275
Comparative transcriptome and metabolite analysis of oil palm and date palm mesocarp that differ dramatically in carbon partitioning275
Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice274
Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor.274
Generation of Rx + /Pax6 + neural retinal precursors from embryonic stem cells273
Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans273
A 40-y record reveals gradual Antarctic sea ice increases followed by decreases at rates far exceeding the rates seen in the Arctic273
Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signaling273
Substantial DNA damage from submicromolar intracellular hydrogen peroxide detected in Hpx - mutants of Escherichia coli273
Nucleotide sequence of the gene for the M r 32,000 thylakoid membrane protein from Spinacia oleracea and 273
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle273
Molecular phylogeny of Archaea from soil273
Disulfide isomerization switches tissue factor from coagulation to cell signaling272
Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes272
Shifting foci of hematopoiesis during reconstitution from single stem cells272
De novo amyloid proteins from designed combinatorial libraries272
Evaluating the evaluation of cancer driver genes272
Seeded growth of β-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure272
Implications for complex cognition from the hafting of tools with compound adhesives in the Middle Stone Age, South Africa272
Stable transformation of the yellow fever mosquito, Aedes aegypti , with the Hermes element from the housefly271
Decomposition of the linking number of a closed ribbon: A problem from molecular biology271
High-grade serous ovarian cancer arises from fallopian tube in a mouse model271
The roles of the two proton input channels in cytochrome c oxidase from Rhodobacter sphaeroides probed by the effects of site-directed mu271
Human modification of global water vapor flows from the land surface271
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds.270
Identifying protein-binding sites from unaligned DNA fragments.270
Highly active catalyst derived from a 3D foam of Fe(PO 3 ) 2 /Ni 2 P for extremely efficient wa270
Increased pollen flow counteracts fragmentation in a tropical dry forest: An example from Swietenia humilis Zuccarini269
Direct Evidence for the Presence of Epstein-Barr Virus DNA and Nuclear Antigen in Malignant Epithelial Cells from Patients with Poorly Differentiated Carcinoma of the Nasopharynx269
How oxygen attacks [FeFe] hydrogenases from photosynthetic organisms269
Osmotic pressure inhibition of DNA ejection from phage269
Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation269
Regulation of Ca 2+ release from mitochondria by the oxidation-reduction state of pyridine nucleotides269
Positive inotropic and lusitropic effects of HNO/NO in failing hearts: Independence from β-adrenergic signaling269
Slow reacting substances of anaphylaxis: Identification of leukotrienes C-1 and D from human and rat sources269
Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.268
Molecular understanding of atmospheric particle formation from sulfuric acid and large oxidized organic molecules268
Evolution of the chordate body plan: New insights from phylogenetic analyses of deuterostome phyla268
Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea268
Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.267
From basic network principles to neural architecture: emergence of spatial-opponent cells.267
Isotopic evidence for large gaseous nitrogen losses from tropical rainforests267
The evolution of primate malaria parasites based on the gene encoding cytochrome b from the linear mitochondrial genome267
Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.267
Automatic classification of prostate cancer Gleason scores from multiparametric magnetic resonance images266
Disentangling pleasure from incentive salience and learning signals in brain reward circuitry266
Early evidence of San material culture represented by organic artifacts from Border Cave, South Africa266
Bias and error in estimates of equilibrium free-energy differences from nonequilibrium measurements265
Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins.265
Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids.265
Molecular cloning of complementary DNA encoding the lignin-forming peroxidase from tobacco: Molecular analysis and tissue-specific expression264
Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange.264
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure.264
Native root-associated bacteria rescue a plant from a sudden-wilt disease that emerged during continuous cropping263
From conversion to aggregation: Protofibril formation of the prion protein263
Simultaneous inference of selection and population growth from patterns of variation in the human genome262
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane262
Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction.261
Data-driven discovery of coordinates and governing equations261
Structure of human serum lipoproteins inferred from compositional analysis.261
RNA-sequencing from single nuclei261
Nicotinic cholinergic signaling in hippocampal astrocytes involves calcium-induced calcium release from intracellular stores261
n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle.260
From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease260
Plants can use protein as a nitrogen source without assistance from other organisms260
Change in chronic disability from 1982 to 2004/2005 as measured by long-term changes in function and health in the U.S. elderly population259
Hydrophobic hydration from small to large lengthscales: Understanding and manipulating the crossover259
Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.259
Neanderthal diet at Vindija and Neanderthal predation: The evidence from stable isotopes259
Efficient biomass pretreatment using ionic liquids derived from lignin and hemicellulose259
Ecological character displacement inPlethodon: Biomechanical differences found from a geometric morphometric study259
Antibiotic Substances From Basidiomycetes258
A protein from the salivary glands of the pea aphid, Acyrthosiphon pisum , is essential in feeding on a host plant258
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3258
Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals257
A global-level assessment of the effectiveness of protected areas at resisting anthropogenic pressures257
TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells257
Intradendritic recordings from hippocampal neurons.257
The earliest archaeological maize ( Zea mays L.) from highland Mexico: New accelerator mass spectrometry dates and their implications257
Gradients of structure–function tethering across neocortex257
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.256
Chaperone-mediated autophagy is involved in the execution of ferroptosis256
Exploring the O -GlcNAc proteome: Direct identification of O -GlcNAc-modified proteins from the brain256
Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models256
Aging of proteins: isolation and identification of a fluorescent chromophore from the reaction of polypeptides with glucose.256
Biosensors from conjugated polyelectrolyte complexes255
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity255
A novel chimeric Ig heavy chain from a teleost fish shares similarities to IgD254
Immunological characterization of the subunit of the 100 A filaments from muscle cells.254
Cancer stemness, intratumoral heterogeneity, and immune response across cancers254
High affinity ligands from in vitro selection: Complex targets253
Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.253
ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.253
Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.253
Identification of 86 candidates for small non-messenger RNAs from the archaeon Archaeoglobus fulgidus253
The nitrogenase system from Azotobacter: two-enzyme requirement for N2 reduction, ATP-dependent H2 evolution, and ATP hydrolysis.253
Scale-dependent interactions between tree canopy cover and impervious surfaces reduce daytime urban heat during summer253
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use253
The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis253
A DNA-Unwinding Protein Isolated from Escherichia coli: Its Interaction with DNA and with DNA Polymerases252
Segregating the core computational faculty of human language from working memory252
Polyfunctional responses by human T cells result from sequential release of cytokines252
Lessons from the past: Biotic recoveries from mass extinctions252
Thermal adaptation analyzed by comparison of protein sequences from mesophilic and extremely thermophilic Methanococcus species252
Checkpoints in the progression of autoimmune disease: lessons from diabetes models.252
Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.251
Laurasian migration explains Gondwanan disjunctions: Evidence from Malpighiaceae251
Interleukin 37 expression protects mice from colitis251
Induction of human cardiomyocyte-like cells from fibroblasts by defined factors250
Inhibition of proteolysis protects hippocampal neurons from ischemia.250
Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: Role of tumor necrosis factor α and IL-18250
Purification and characterization of a neurite extension factor from bovine brain.250
α-KETO ACID DEHYDROGENASE COMPLEXES, XI. COMPARATIVE STUDIES OF REGULATORY PROPERTIES OF THE PYRUVATE DEHYDROGENASE COMPLEXES FROM KIDNEY, HEART, AND LIVER MITOCHONDRIA250
An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent249
Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein.249
Genomic data do not support comb jellies as the sister group to all other animals249
Cleavage motifs of the yeast 20S proteasome β subunits deduced from digests of enolase 1248
Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer248
Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.248
Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma248
Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factors248
Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.248
An inhibitor persistently decreased enteric methane emission from dairy cows with no negative effect on milk production248
Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication248
Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2.248
Development of an artificial cell, from self-organization to computation and self-reproduction248
Global synthesis of conservation studies reveals the importance of small habitat patches for biodiversity247
Sequences of Pituitary and Placental Lactogenic and Growth Hormones: Evolution from a Primordial Peptide by Gene Reduplication247
Neuroectodermal differentiation from mouse multipotent adult progenitor cells247
Production of hyperpolarized [1,4- 13 C 2 ]malate from [1,4- 13 C 2 247
Caenorhabditis elegans responses to bacteria from its natural habitats247
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.247
Increasing crop heterogeneity enhances multitrophic diversity across agricultural regions247
An early modern human from the Peştera cu Oase, Romania247
Stabilizing the Earth’s climate is not a losing game: Supporting evidence from public goods experiments247
Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4.246
Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories246
Holographic acoustic tweezers246
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells246
The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice.246
The single-cell transcriptomic landscape of early human diabetic nephropathy246
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.246
Three independent biological mechanisms cause exercise-associated hyponatremia: Evidence from 2,135 weighed competitive athletic performances246
Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane246
Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes245
Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis245
Prediction of membrane-protein topology from first principles245
Parathyroid hormone-related peptide (PTHrP) regulates fetal–placental calcium transport through a receptor distinct from the PTH/PTHrP receptor245
Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia.245
In vitro self-assembly of tailorable nanotubes from a simple protein building block244
Long-term renewal of hair follicles from clonogenic multipotent stem cells244
Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages244
Epoxidation of olefins by cytochrome P450: Evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant244
HIV rebounds from latently infected cells, rather than from continuing low-level replication244
Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis244
RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA.244
Extraordinarily high spider densities on islands: flow of energy from the marine to terrestrial food webs and the absence of predation.244
Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease.244
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients243
Structure of ice crystallized from supercooled water243
Reconstructing evolutionary trees from DNA and proteinsequences: paralinear distances.243
The complete sequence of the 1,683-kb pSymB megaplasmid from the N 2 -fixing endosymbiont Sinorhizobium meliloti243
Density-dependent decline of host abundance resulting from a new infectious disease243
Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: protein-cofactor (bacteriochlorophyll, bacteriopheophytin, and carotenoid) interactions.243
Side-chain hydrophobicity scale derived from transmembrane protein folding into lipid bilayers243
Origin of nanomechanical cantilever motion generated from biomolecular interactions242
Evidence for the natural occurrence of zeatin and derivatives: compounds from maize which promote cell division.242
Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films242
Evidence for a cholinergic projection to neocortex from neurons in basal forebrain.242
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum242
Brain-derived neurotrophic factor promotes the survival of neurons arising from the adult rat forebrain subependymal zone.242
Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species242
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release241
Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction.241
Apoptotic cells protect mice from autoimmune inflammation by the induction of regulatory B cells241
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells.241
Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasiteLeishmania major241
Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes241
Novel genes derived from noncoding DNA in Drosophila melanogaster are frequently X-linked and exhibit testis-biased expression241
IL-33 augments substance P–induced VEGF secretion from human mast cells and is increased in psoriatic skin240
Supramolecular structure of the photosystem II complex from green plants and cyanobacteria.240
Primary structure of corticotropin-releasing factor from ovine hypothalamus.240
Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory239
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells239
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin239
Probing essential oil biosynthesis and secretion by functional evaluation of expressed sequence tags from mint glandular trichomes239
Astrocytes regulate cortical state switching in vivo239
Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors239
An essential role for orexins in emergence from general anesthesia239
Wildfires and climate change push low-elevation forests across a critical climate threshold for tree regeneration239
Epoxide as a precursor to secondary organic aerosol formation from isoprene photooxidation in the presence of nitrogen oxides238
Growth model interpretation of planet size distribution238
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells238
Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis: implications for a mechanism of action.238
Histidine kinase activity of the ETR1 ethylene receptor from Arabidopsis237
Minimizing a binding domain from protein A.237
Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.237
Multiple sclerosis: Comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells237
Recent common ancestry of human Y chromosomes: Evidence from DNA sequence data236
Climate change and health costs of air emissions from biofuels and gasoline236
Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells.236
Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries236
REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES235
Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the 235
Early light-induced proteins protect Arabidopsis from photooxidative stress235
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality235
Inheritance of selected pathotoxin resistance in maize plants regenerated from cell cultures235
Diverse syntrophic partnerships from deep-sea methane vents revealed by direct cell capture and metagenomics235
Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways235
UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota234
Ammonia emission control in China would mitigate haze pollution and nitrogen deposition, but worsen acid rain234
Rates of species loss from Amazonian forest fragments234
Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4.234
Replicational release of geminivirus genomes from tandemly repeated copies: evidence for rolling-circle replication of a plant viral DNA.234
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota234
Identification of an Antigen from Normal Human Tissue That Crossreacts with the Carcinoembryonic Antigen234
Plant-derived coumarins shape the composition of an Arabidopsis synthetic root microbiome234
Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors.234
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening234
Type III secretion systems and bacterial flagella: Insights into their function from structural similarities234
The origin of European cattle: Evidence from modern and ancient DNA233
Molecular cloning and characterization of GPA1, a G protein alpha subunit gene from Arabidopsis thaliana.233
Retaining cell–cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer233
The glutathione redox couple modulates zinc transfer from metallothionein to zinc-depleted sorbitol dehydrogenase233
Establishment of an animal–bacterial association: Recruiting symbiotic vibrios from the environment233
Predicting the risk of extinction from shared ecological characteristics233
Ice-shelf collapse from subsurface warming as a trigger for Heinrich events232
Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies.232
Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana232
Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition232
Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly232
Muscle-like fatigue-resistant hydrogels by mechanical training232
Cystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lung231
A gene from the cellulose synthase-like C family encodes a β-1,4 glucan synthase231
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.231
Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.231
Protein folding kinetics and thermodynamics from atomistic simulation231
Toward a better understanding and quantification of methane emissions from shale gas development231
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.230
Structure of the reaction center from Rhodobacter sphaeroides R-26: protein-cofactor (quinones and Fe2+) interactions.230
Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences.230
Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation230
Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes230
Pro-coagulant state resulting from high levels of soluble P-selectin in blood230
Climate forcing from the transport sectors230
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells230
The role of side-chain interactions in the early steps of aggregation: Molecular dynamics simulations of an amyloid-forming peptide from the yeast prion Sup35230
Drugging an undruggable pocket on KRAS230
Evolution of gilled mushrooms and puffballs inferred from ribosomal DNA sequences230
Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds229
Structure and comparison of the oxytocin and vasopressin genes from rat.229
The candidate tumor suppressor gene, RASSF1A , from human chromosome 3p21.3 is involved in kidney tumorigenesis229
The herpes simplex virus 1 protein kinase U S 3 is required for protection from apoptosis induced by the virus229
Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets229
Construction of shuttle vectors capable of conjugative transfer from Escherichia coli to nitrogen-fixing filamentous cyanobacteria.229
Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation228
Gene sequences suggest inactivation of alpha-1,3-galactosyltransferase in catarrhines after the divergence of apes from monkeys.228
Continuous Lymphoid Cell Lines with Characteristics of B Cells (Bone-Marrow-Derived), Lacking the Epstein-Barr Virus Genome and Derived from Three Human Lymphomas228
Characterization of a novel, low-molecular-weight DNA-binding protein from Escherichia coli.228
De novogeneration of antigen-specific CD4+CD25+regulatory T cells from human CD4+CD25cells228
The systemin receptor SR160 from Lycopersicon peruvianum is a member of the LRR receptor kinase family228
Considering adaptive genetic variation in climate change vulnerability assessment reduces species range loss projections228
Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells.227
Fluorescence of Lysozyme: Emissions from Tryptophan Residues 62 and 108 and Energy Migration227
Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity.227
Large-scale analysis of test–retest reliabilities of self-regulation measures227
Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene.227
Initial electron-transfer in the reaction center from Rhodobacter sphaeroides.227
Absence of branches from xylan in Arabidopsis gux mutants reveals potential for simplification of lignocellulosic biomass226
Purification and initial characterization of a type beta transforming growth factor from human placenta.226
Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus particles.226
Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles.226
Oligosaccharide-specific induction of interleukin 10 production by B220+ cells from schistosome-infected mice: a mechanism for regulation of CD4+ T-cell subsets.226
mRNA structure regulates protein expression through changes in functional half-life226
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells226
Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore.226
Anomalous levels of Cl transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory225
Estimation of divergence times from multiprotein sequences for a few mammalian species and several distantly related organisms225
Vaccine assembly from surface proteins ofStaphylococcus aureus225
T7 Early RNAs and Escherichia coli Ribosomal RNAs are Cut from Large Precursor RNAs In Vivo by Ribonuclease III225
High-frequency gene transfer from the chloroplast genome to the nucleus225
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-β structure225
Retrocyclin: A primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1225
Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects.225
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube225
National hiring experiments reveal 2:1 faculty preference for women on STEM tenure track225
The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor224
Truncated hemoglobin HbN protects Mycobacterium bovis from nitric oxide224
Structural and functional divergence of insect CYP6B proteins: From specialist to generalist cytochrome P450224
Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.224
Statistical inference of the generation probability of T-cell receptors from sequence repertoires224
Insights into salt tolerance from the genome of Thellungiella salsuginea224
Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys).224
Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle.224
Stimulation of Ca 2+ -dependent neurotransmitter release and presynaptic nerve terminal protein phosphorylation by calmodulin and a calmodulin-like protein isolated 223
Identification of an allatostatin from the tobacco hornworm Manduca sexta.223
Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.223
Hydrophobicity of protein surfaces: Separating geometry from chemistry223
Predicting protein functions from redundancies in large-scale protein interaction networks223
Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes223
Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid.223
Electron microscopic study of supramolecular liquid crystalline polymers formed by molecular-recognition-directed self-assembly from complementary chiral components.223
Memory from the dynamics of intrinsic membrane currents223
Variation in leaf flushing date influences autumnal senescence and next year’s flushing date in two temperate tree species223
Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells223
Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats223
Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide.223
Mapping the information flow from one brain to another during gestural communication223
Evidence for a fundamental and pervasive shift away from nature-based recreation223
Late Neandertals and the intentional removal of feathers as evidenced from bird bone taphonomy at Fumane Cave 44 ky B.P., Italy222
Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix.222
Predictable waves of sequential forest degradation and biodiversity loss spreading from an African city222
Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by "calcium-dependent regulator".222
How the immune system works to protect the host from infection: A personal view222
Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease222
Matrix protein from Escherichia coli outer membranes forms voltage-controlled channels in lipid bilayers.222
Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.221
Evidence for landscape-level, pollen-mediated gene flow from genetically modified creeping bentgrass with CP4 EPSPS as a marker221
The diversity of dolichol-linked precursors to Asn-linked glycans likely results from secondary loss of sets of glycosyltransferases221
IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor κB ligand and tumor necrosis factor α from T cells220
Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade220
Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones.220
Determination of water mass properties of water pumped down from the Ekman layer to the geostrophic flow below220
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes220
Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer220
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.220
Color from hierarchy: Diverse optical properties of micron-sized spherical colloidal assemblies219
An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication219
Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells219
Magnetic field-induced assembly of oriented superlattices from maghemite nanocubes219
Complete nucleotide sequence of a 23S ribosomal RNA gene from Escherichia coli.219
Genomic and proteomic characterization of “ Candidatus Nitrosopelagicus brevis”: An ammonia-oxidizing archaeon from the open ocean218
Listeria-based cancer vaccines that segregate immunogenicity from toxicity218
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.218
Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.218
Automated vocal analysis of naturalistic recordings from children with autism, language delay, and typical development218
Aspartic acid racemization in tooth enamel from living humans.218
Separating intrinsic from extrinsic fluctuations in dynamic biological systems218
Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients218
From hematopoiesis to neuropoiesis: Evidence of overlapping genetic programs218
An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mic217
Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-Å resolution217
Phylogenetic discovery bias in Bacillus anthracis using single-nucleotide polymorphisms from whole-genome sequencing217
Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity217
Fibrin monomer protects thrombin from inactivation by heparin-antithrombin III: implications for heparin efficacy.217
Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies217
Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: Implications for glaucoma217
Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function217
Pro-phenol oxidase activating proteinase from an insect, Manduca sexta: A bacteria-inducible protein similar to Drosophila easter216
Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs.216
The goat domestication process inferred from large-scale mitochondrial DNA analysis of wild and domestic individuals216
A detailed picture of the origin of the Australian dingo, obtained from the study of mitochondrial DNA216
Histidines, heart of the hydrogen ion channel from influenza A virus: Toward an understanding of conductance and proton selectivity216
Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells216
Crystal structure of the BTB domain from PLZF215
Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease215
Loss of centromeric histone H3 (CENH3) from centromeres precedes uniparental chromosome elimination in interspecific barley hybrids215
Evidence that the 42- and 40-amino acid forms of amyloid β protein are generated from the β-amyloid precursor protein by different protease activities215
Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region215
Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling.215
Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury214
Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.214
CAX1, an H+/Ca2+ antiporter from Arabidopsis.214
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture214
In-depth study of Mollivirus sibericum , a new 30,000-y-old giant virus infecting Acanthamoeba214
Fallout plume of submerged oil from Deepwater Horizon213
Release of ovoperoxidase from sea urchin eggs hardens the fertilization membrane with tyrosine crosslinks213
Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.213
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.213
High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1213
Inhibitor binding changes domain mobility in the iron–sulfur protein of the mitochondrial bc 1 complex from bovine heart212
Feedforward excitation of the hippocampus by afferents from the entorhinal cortex: redefinition of the role of the trisynaptic pathway.212
Deep learning predicts path-dependent plasticity212
Drivers of household food availability in sub-Saharan Africa based on big data from small farms212
Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-Å resolution212
Encephalization and allometric trajectories in the genusHomo: Evidence from the Neandertal and modern lineages212
Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity212
NAL1 allele from a rice landrace greatly increases yield in modern indica cultivars212
Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population212
A two-subunit cytochrome c oxidase (cytochrome aa3) from Paracoccus dentrificans.212
Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed/refractory multiple myeloma211
An ammonite trapped in Burmese amber211
A unique virulence factor for proliferation and dwarfism in plants identified from a phytopathogenic bacterium211
Small RNA genes expressed from Staphylococcus aureus genomic and pathogenicity islands with specific expression among pathogenic strains211
Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration211
Successional dynamics in Neotropical forests are as uncertain as they are predictable211
High sensitivity and interindividual variability in the response of the human circadian system to evening light210
Correlating microbial community profiles with geochemical data in highly stratified sediments from the Arctic Mid-Ocean Ridge210
Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins.210
Selective Elimination of the Exonuclease Activity of the Deoxyribonucleic Acid Polymerase from Escherichia coli B by Limited Proteolysis210
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.210
Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney.210
Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles.210
Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides210
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue.210
A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans209
Mechanism of Activation by Adenosine 3′:5′-Cyclic Monophosphate of a Protein Phosphokinase from Rabbit Reticulocytes209
Expression and nucleotide sequence of a plasmid-determined divalent cation efflux system from Alcaligenes eutrophus.208
The temporal lobe is a target of output from the basal ganglia.208
Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease208
Metal-dependent folding of a single zinc finger from transcription factor IIIA.208
Class-level relationships in the phylum Cnidaria: evidence from mitochondrial genome structure.208
Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions208
Phylogenomics reveals the evolutionary timing and pattern of butterflies and moths207
A 2,300-year-long annually resolved record of the South American summer monsoon from the Peruvian Andes207
The macroscopic delamination of thin films from elastic substrates207
Targeting RIPK1 for the treatment of human diseases207
Complete nucleotide sequence of the chloroplast genome from the green alga Chlorella vulgaris : The existence of genes possibly involved in chloroplast division207
Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells207
Interfacial engineering of cobalt sulfide/graphene hybrids for highly efficient ammonia electrosynthesis207
Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain207
An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.207
Predicting fate from early connectivity in a social network207
Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervation206
Yeast artificial chromosome libraries containing large inserts from mouse and human DNA.206
Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks206
Amino Acid Sequence of Human apoLp-Gln-II (apoA-II), an Apolipoprotein Isolated from the High-Density Lipoprotein Complex206
A previously unidentified host protein protects retroviral DNA from autointegration206
Erythropoietin both protects from and reverses experimental diabetic neuropathy206
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins206
Peptide ligands for a sugar-binding protein isolated from a random peptide library.206
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction206
Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1206
Conditional and specific NF-κB blockade protects pancreatic beta cells from diabetogenic agents205
Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets205
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.205
The early Upper Paleolithic human skeleton from the Abrigo do Lagar Velho (Portugal) and modern human emergence in Iberia205
Identification of hepatoprotective flavonolignans from silymarin205
Renal reabsorption in 3D vascularized proximal tubule models205
Protection from mitochondrial complex II inhibitionin vitroandin vivoby Nrf2-mediated transcription205
Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body205
Recurrence is required to capture the representational dynamics of the human visual system205
Global economic potential for reducing carbon dioxide emissions from mangrove loss204
Development of structure–function coupling in human brain networks during youth204
Metalearners for estimating heterogeneous treatment effects using machine learning204
Isolation of Microtubule Protein from Cultured Mouse Neuroblastoma Cells204
Neurogenesis and widespread forebrain migration of distinct GABAergic neurons from the postnatal subventricular zone204
Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation204
Purification and characterization of a nicotinic acetylcholine receptor from rat brain.204
In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library.204
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP203
ARC5, a cytosolic dynamin-like protein from plants, is part of the chloroplast division machinery203
Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells203
Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors203
Plants and people from the Early Neolithic to Shang periods in North China203
Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4203
Subacute neuropathological effects of microplanar beams of x-rays from a synchrotron wiggler.203
Replication and expression of plasmids from Staphylococcus aureus in Bacillus subtilis.203
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences202
Two Types of Molecular Evolution. Evidence from Studies of Interspecific Hybridization202
Social media’s enduring effect on adolescent life satisfaction202
From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium202
Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei.202
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption202
Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d I.202
Cochlear mechanisms from a phylogenetic viewpoint202
Methane emissions from natural gas infrastructure and use in the urban region of Boston, Massachusetts201
Ebola virus-like particles protect from lethal Ebola virus infection201
The particle SSV1 from the extremely thermophilic archaeon Sulfolobus is a virus: demonstration of infectivity and of transfection with viral DNA.201
Forces between Protein Molecules in Solution Arising from Fluctuations in Proton Charge and Configuration201
Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis201
Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.201
Cyanophycin Granules from the Blue-Green Alga Anabaena cylindrica: A Reserve Material Consisting of Copolymers of Aspartic Acid and Arginine201
STUDIES ON THE PROTEIN COMPONENTS OF CILIA FROM TETRAHYMENA PYRIFORMIS201
Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants201
IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells201
Proteome-scale purification of human proteins from bacteria201
Membrane-dependent oligomeric structure and pore formation of a β-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR200
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells200
Nitrogen management and the future of food: Lessons from the management of energy and carbon200
Bean α-amylase inhibitor 1 in transgenic peas ( Pisum sativum ) provides complete protection from pea weevil ( Bruchus pisorum ) under fie200
Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance.200
Evidence for a first-order liquid-liquid transition in high-pressure hydrogen from ab initio simulations200
Dynamics of shear-induced ATP release from red blood cells200
Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease200
Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner200
Microtubule release from the centrosome200
Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells199
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells199
Hamiltonella defensa , genome evolution of protective bacterial endosymbiont from pathogenic ancestors199
Realizing the potential of dielectric elastomer artificial muscles199
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis199
Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis.199
Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action.199
A NERVE GROWTH-STIMULATING FACTOR ISOLATED FROM SNAKE VENOM199
A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae199
A far-red fluorescent protein with fast maturation and reduced oligomerization tendency from Entacmaea quadricolor (Anthozoa, Actinaria)199
The insulation of genes from external enhancers and silencing chromatin199
Shape-shifting structured lattices via multimaterial 4D printing199
Direct observation of aqueous secondary organic aerosol from biomass-burning emissions198
Late Paleocene fossils from the Cerrejón Formation, Colombia, are the earliest record of Neotropical rainforest198
A chromatin insulator protects retrovirus vectors from chromosomal position effects198
CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly198
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.198
Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening198
Paper-based microfluidics for DNA diagnostics of malaria in low resource underserved rural communities198
SERUM-MEDIATED PROTECTION OF NEOPLASTIC CELLS FROM INHIBITION BY LYMPHOCYTES IMMUNE TO THEIR TUMOR-SPECIFIC ANTIGENS198
Heat shock protein synthesis and thermotolerance in Cataglyphis, an ant from the Sahara desert.198
AMINO ACID TRANSFER FROM AMINOACYL-RIBONUCLEIC ACIDS TO PROTEIN ON RIBOSOMES OF ESCHERICHIA COLI198
Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli197
Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.197
Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor.197
Total Reconstitution of Functionally Active 50S Ribosomal Subunits from Escherichia coli197
The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activat197
Fighting malaria with engineered symbiotic bacteria from vector mosquitoes197
Post-stress bacterial cell death mediated by reactive oxygen species197
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity197
Design of chiral ligands for asymmetric catalysis: From C 2 -symmetric P,P- and N,N-ligands to sterically and electronically nonsymmetrical P,N-ligands197
Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations197
Vacuolar Na + /H + antiporter cation selectivity is regulated by calmodulin from within the vacuole in a Ca 2+196
Divergent selection during speciation of Lake Malawi cichlid fishes inferred from parallel radiations in nuptial coloration196
Toward understanding cancer stem cell heterogeneity in the tumor microenvironment196
Podocytes use FcRn to clear IgG from the glomerular basement membrane196
Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.196
Formation of cyanide from carbon 1 of 1-aminocyclopropane-1-carboxylic acid during its conversion to ethylene196
Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH196
Physical effects underlying the transition from primitive to modern cell membranes196
Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: symmetry relations and sequence comparisons between different species.195
THE NATURAL C 14 CONTENTS OF MATERIALS FROM HARD-WATER LAKES195
Materials derived from biomass/biodegradable materials.195
Insect immunity: isolation from immune blood of the dipteran Phormia terranovae of two insect antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides.195
A ligand for the aryl hydrocarbon receptor isolated from lung195
Flexible electrical recording from cells using nanowire transistor arrays195
Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus195
The Importance of Gene Rearrangement in Evolution: Evidence from Studies on Rates of Chromosomal, Protein, and Anatomical Evolution195
An iterative method for extracting energy-like quantities from protein structures.195
THE RATE OF MOLECULAR EVOLUTION CONSIDERED FROM THE STANDPOINT OF POPULATION GENETICS194
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics194
Heat shock induces the release of fibroblast growth factor 1 from NIH 3T3 cells.194
EXCESSIVE GROWTH OF THE SYMPATHETIC GANGLIA EVOKED BY A PROTEIN ISOLATED FROM MOUSE SALIVARY GLANDS194
Human remains from Zhirendong, South China, and modern human emergence in East Asia194
Specific alteration of the oxidation potential of the electron donor in reaction centers from Rhodobacter sphaeroides.194
Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions194
A carbonic anhydrase from the archaeon Methanosarcina thermophila.194
Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication194
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis.194
Sphericity and symmetry breaking in the formation of Frank–Kasper phases from one component materials194
Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte.193
Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients.193
DNA sequence of the mitochondrial hypervariable region II from the Neandertal type specimen193
Stretchable materials of high toughness and low hysteresis193
An early Australopithecus afarensis postcranium from Woranso-Mille, Ethiopia193
Restoration of an absent G 1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation193
Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure193
Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.193
Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo193
Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule.193
Structural and thermodynamic limits of layer thickness in 2D halide perovskites192
Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro.192
Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene.192
Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells192
Structural changes at microtubule ends accompanying GTP hydrolysis: Information from a slowly hydrolyzable analogue of GTP, guanylyl (α,β)methylenediphosphonate192
Dimeric structure of single chloride channels from Torpedo electroplax.192
Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana192
Antiviral and antitumor peptides from insects192
Spontaneous generation of hydrogen peroxide from aqueous microdroplets192
A bent monomeric conformation of myosin from smooth muscle.191
Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.191
Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns191
The broad spectrum revisited: Evidence from plant remains191
Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients191
Canonical histidine kinase activity of the transmitter domain of the ETR1 ethylene receptor from Arabidopsis is not required for signal transmission191
A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans191
Evolution of individuality during the transition from unicellular to multicellular life191
Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1 - gfp knock-in mic191
Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage.191
Direct visualization of antigen-specific T cells: HTLV-1 Tax11–19- specific CD8+T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients190
Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms.190
Telomere shortening rate predicts species life span190
Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality190
From estrogen to androgen receptor: A new pathway for sex hormones in prostate190
Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells190
Evolution of the fungal self-fertile reproductive life style from self-sterile ancestors190
Circular RNAs from transcripts of the rat cytochrome P450 2C24 gene: correlation with exon skipping.190
Malaria risk and temperature: Influences from global climate change and local land use practices189
Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques189
Fundamental limits on dynamic inference from single-cell snapshots189
Crown gall oncogenesis: evidence that a T-DNA gene from the Agrobacterium Ti plasmid pTiA6 encodes an enzyme that catalyzes synthesis of indoleacetic acid.189
From flies' eyes to our ears: Mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30188
A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function188
Miniature endplate current rise times less than 100 microseconds from improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle.188
Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells188
Mechanisms of Lysosomal Enzyme Release from Human Leukocytes: Microtubule Assembly and Membrane Fusion Induced by a Component of Complement188
Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain188
Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.188
Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold188
Evidence for last interglacial chronology and environmental change from Southern Europe187
PHDs overactivation during chronic hypoxia “desensitizes” HIFα and protects cells from necrosis187
Optical edge detection based on high-efficiency dielectric metasurface187
The HcrVf2 gene from a wild apple confers scab resistance to a transgenic cultivated variety187
A beta-D-galactoside binding protein from electric organ tissue of Electrophorus electricus.187
An Arabidopsis thaliana high-affinity molybdate transporter required for efficient uptake of molybdate from soil187
Growth in suckling-mouse brain of "IBV-like" viruses from patients with upper respiratory tract disease.187
Leukotriene D: a slow reacting substance from rat basophilic leukemia cells.187
Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers187
Imaging Dirac-mass disorder from magnetic dopant atoms in the ferromagnetic topological insulator Cr x (Bi 0.1 Sb 187
Phylogenetic relationships among domesticated and wild species of Cucurbita (Cucurbitaceae) inferred from a mitochondrial gene: Implications for crop plant evolution and187
Method to determine the reading frame of a protein from the purine/pyrimidine genome sequence and its possible evolutionary justification.187
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation187
Multiple origins of viral capsid proteins from cellular ancestors187
Label-free DNA imaging in vivo with stimulated Raman scattering microscopy187
Identification of a novel selD homolog from Eukaryotes, Bacteria, and Archaea: Is there an autoregulatory mechanism in selenocysteine metabolism?187
Morphological homoplasy, life history evolution, and historical biogeography of plethodontid salamanders inferred from complete mitochondrial genomes187
Information about movement direction obtained from synchronous activity of motor cortical neurons187
T-cell lines established from human T-lymphocytic neoplasias by direct response to T-cell growth factor.186
Compound-specific carbon isotopes from Earth’s largest flood basalt eruptions directly linked to the end-Triassic mass extinction186
Formation of free nitric oxide from l-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase.186
Complete amino acid sequence of beta-tubulin from porcine brain.186
Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics186
Evidence from internet search data shows information-seeking responses to news of local COVID-19 cases186
Scales of benthic–pelagic coupling and the intensity of species interactions: From recruitment limitation to top-down control186
Controlled surface-induced flows from the motion of self-assembled colloidal walkers186
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases.186
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes186
RNA design rules from a massive open laboratory186
Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition186
Ethylene-regulated gene expression: molecular cloning of the genes encoding an endochitinase from Phaseolus vulgaris.186
Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric m186
Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma.185
cDNA cloning of prophenoloxidase from the freshwater crayfish Pacifastacus leniusculus and its activation.185
The identification of functional modules from the genomic association of genes185
Evolution of interlayer and intralayer magnetism in three atomically thin chromium trihalides185
Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing185
Inhibition by prostaglandins of leukotriene B4 release from activated neutrophils.185
Kinesin’s processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains185
Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: From pipe dreams to (therapeutic) pipelines185
Country-wide rainfall maps from cellular communication networks185
Historical change of El Niño properties sheds light on future changes of extreme El Niño185
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.185
Spontaneous electrical activity of interstitial cells of Cajal isolated from canine proximal colon.185
Inverting dynamic force microscopy: From signals to time-resolved interaction forces185
Membrane tube formation from giant vesicles by dynamic association of motor proteins185
Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways185
Quantification of HIV-1 latency reversal in resting CD4 + T cells from patients on suppressive antiretroviral therapy185
Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.185
High-yield hydrogen production from biomass by in vitro metabolic engineering: Mixed sugars coutilization and kinetic modeling184
Candidate odorant receptors from the malaria vector mosquito Anopheles gambiae and evidence of down-regulation in response to blood feeding184
Chemocyanin, a small basic protein from the lily stigma, induces pollen tube chemotropism184
Localization of RNA from heat-induced polysomes at puff sites in Drosophila melanogaster.184
Global evaluation of biofuel potential from microalgae184
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand.184
Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase184
Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.184
Apparent thinning of human visual cortex during childhood is associated with myelination184
Low ambient humidity impairs barrier function and innate resistance against influenza infection184
11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene.184
Crystal structure and activities of EXPB1 (Zea m 1), a β-expansin and group-1 pollen allergen from maize184
Does recombination improve selection on codon usage? Lessons from nematode and fly complete genomes184
Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer184
Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element.183
Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken.183
Birth of a chimeric primate gene by capture of the transposase gene from a mobile element183
Origins and dispersals of Pacific peoples: Evidence from mtDNA phylogenies of the Pacific rat183
Cotranslational insertion of selenocysteine into formate dehydrogenase from Escherichia coli directed by a UGA codon.183
Rubredoxin: a new electron transfer protein from Clostridium pasteurianum.183
Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains.182
Internal and interfacial dielectric properties of cytochrome c from molecular dynamics in aqueous solution.182
Developmental and adult phenotyping directly from mutant embryonic stem cells182
ISOLATION OF β-GLUCAN SYNTHETASE PARTICLES FROM PLANT CELLS AND IDENTIFICATION WITH GOLGI MEMBRANES182
Interspecific cytoplasmic gene flow in the absence of nuclear gene flow: evidence from Drosophila.182
Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods.182
Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster.182
Rescue of a segmented negative-strand RNA virus entirely from cloned complementary DNAs182
Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli.181
Warming-induced northwestward migration of the East Asian monsoon rain belt from the Last Glacial Maximum to the mid-Holocene181
THEMATICS: A simple computational predictor of enzyme function from structure181
Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease.181
Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells181
Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and T-cell infectivity.180
Disulfooxy fatty acids from the American bird grasshopper Schistocerca americana , elicitors of plant volatiles180
Flows of knowledge from universities and federal laboratories: Modeling the flow of patent citations over time and across institutional and geographic boundaries180
Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells.180
Gas-phase ions of solute species from charged droplets of solutions180
The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation180
Assessment of ground-based atmospheric observations for verification of greenhouse gas emissions from an urban region180
Mechanisms of sampling interstitial fluid from skin using a microneedle patch180
Crystal structure of the archaeal ammonium transporter Amt-1 from Archaeoglobus fulgidus180
Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Se180
Recent speciation of Capsella rubella from Capsella grandiflora , associated with loss of self-incompatibility and an extreme bottleneck180
A pure population of lung alveolar epithelial type II cells derived from human embryonic stem cells180
Global atmospheric black carbon inferred from AERONET180
Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang.180
Stearoyl-acyl carrier protein delta 9 desaturase from Ricinus communis is a diiron-oxo protein.179
Mechanistic evidence for tracking the seasonality of photosynthesis with solar-induced fluorescence179
NanoFlares for the detection, isolation, and culture of live tumor cells from human blood179
Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.179
Marine fish may be biochemically constrained from inhabiting the deepest ocean depths179
Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin.179
Generation of hypoimmunogenic human pluripotent stem cells179
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase179
Committed sea-level rise for the next century from Greenland ice sheet dynamics during the past decade179
Structure of the reaction center from Rhodobacter sphaeroides R-26: membrane-protein interactions.179
Purification and some characteristics of human T-cell growth factor from phytohemagglutinin-stimulated lymphocyte-conditioned media.179
Earth history and the passerine superradiation179
Nucleic acid (cDNA) and amino acid sequences of alpha-type gliadins from wheat (Triticum aestivum).179
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.179
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι178
Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote.178
Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing.178
Navigating from hippocampus to parietal cortex178
Prediction of protein deamidation rates from primary and three-dimensional structure178
Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: Role in restricted conformational mobility and compaction of native state178
"Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity.178
Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea.178
Dopamine prediction error responses integrate subjective value from different reward dimensions178
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration178
Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors178
High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years178
Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix178
COMPOSITION OF SURFACE-ACTIVE MATERIAL ISOLATED FROM BEEF LUNG178
Novel nanocomposites from spider silk–silica fusion (chimeric) proteins177
A family of concanavalin A-binding peptides from a hexapeptide epitope library.177
ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable177
Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission177
Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation177
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling.177
Automatic generation of primary sequence patterns from sets of related protein sequences.177
A remarkable, precisely timed release of hyperglycemic hormone from endocrine cells in the gut is associated with ecdysis in the crab Carcinus maenas177
Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.177
Ornaments of the earliest Upper Paleolithic: New insights from the Levant177
Reconstitution in planar lipid bilayers of a Ca2+-dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle.177
Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas.176
Inducers of interferon and host resistance. I. Double-stranded RNA from extracts of Penicillium funiculosum.176
Inhibition of Collagen Secretion from Bone and Cultured Fibroblasts by Microtubular Disruptive Drugs176
High-performance all-solid-state batteries enabled by salt bonding to perovskite in poly(ethylene oxide)176
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels176
Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus.176
Inferring phylogenies from DNA sequences of unequal base compositions.176
Coupling of catecholamine receptor from one cell with adenylate cyclase from another cell by cell fusion.176
Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge176
High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries176
A cooperative oxygen-binding hemoglobin from Mycobacterium tuberculosis176
Expression genetics in cancer: Shifting the focus from DNA to RNA176
The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductas176
RID1 , encoding a Cys2/His2-type zinc finger transcription factor, acts as a master switch from vegetative to floral development in rice175
Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.175
Purification and Properties of Reconstitutively Active and Inactive Adenosinetriphosphatase from Escherichia coli175
Inverted repeats in chloroplast DNA from higher plants175
Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling.175
High density lipoprotein loses its effect to stimulate efflux of cholesterol from foam cells after oxidative modification.175
Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence175
Toward understanding the impact of artificial intelligence on labor175
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death175
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product175
Post-translational cleavage of presecretory proteins with an extract of rough microsomes from dog pancreas containing signal peptidase activity.175
Effects of α-tubulin acetylation on microtubule structure and stability175
Multicomponent RNA plant virus infection derived from cloned viral cDNA174
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast174
Massive horizontal transfer of mitochondrial genes from diverse land plant donors to the basal angiosperm Amborella174
RNS2: a senescence-associated RNase of Arabidopsis that diverged from the S-RNases before speciation.174
Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells174
From extortion to generosity, evolution in the Iterated Prisoner’s Dilemma174
Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies174
Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel174
Biosynthetic origin of natural products isolated from marine microorganism–invertebrate assemblages174
Engineering bone tissue substitutes from human induced pluripotent stem cells174
Potential for reduced methane and carbon dioxide emissions from livestock and pasture management in the tropics174
Land–atmosphere feedbacks exacerbate concurrent soil drought and atmospheric aridity174
Natural and synthetic prion structure from X-ray fiber diffraction174
Hypervirulent mutant ofMycobacterium tuberculosisresulting from disruption of themce1operon174
Membrane orientation of the FMO antenna protein from Chlorobaculum tepidum as determined by mass spectrometry-based footprinting174
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples173
An optomechanical transducer in the blue light receptor phototropin from Avena sativa173
Green Revolution research saved an estimated 18 to 27 million hectares from being brought into agricultural production173
Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library.173
Noninvasive imaging of immune responses173
Precursor polyprotein for multiple neuropeptides secreted from the suboesophageal ganglion of the silkworm Bombyx mori: characterization of the cDNA encoding the diapause hormone precursor and identif173
Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxide173
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli173
The road from Santa Rosalia: A faster tempo of evolution in tropical climates173
T-DNA from Agrobacterium Ti plasmid is in the nuclear DNA fraction of crown gall tumor cells173
The intrinsic behavior of lithium fluoride in solid electrolyte interphases on lithium173
Angiotensin II receptor subtypes are coupled with distinct signal-transduction mechanisms in neurons and astrocytes from rat brain.173
Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma.173
Transcranial alternating current stimulation entrains single-neuron activity in the primate brain173
Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli -expressed libraries172
Structure and function from the circadian clock protein KaiA of Synechococcus elongatus : A potential clock input mechanism172
Pancreatic islet-specific T-cell clones from nonobese diabetic mice.172
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network172
The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH172
Direct transfer of cloned genes from bacteria to mammalian cells.172
Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1172
The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes.172
Redefining bilingualism as a spectrum of experiences that differentially affects brain structure and function172
KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome171
Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity171
Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.171
Composition of the gut microbiota modulates the severity of malaria171
Learning data-driven discretizations for partial differential equations171
An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors171
Release of gamma-aminobutyric acid from inhibitory nerves of lobster.171
The harmonic mean p -value for combining dependent tests171
Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid.171
Prairie strips improve biodiversity and the delivery of multiple ecosystem services from corn–soybean croplands171
Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver.171
Heat transfer from nanoparticles: A corresponding state analysis171
Human herpesvirus 7 is a T-lymphotropic virus and is related to, but significantly different from, human herpesvirus 6 and human cytomegalovirus.170
α-Helix formation in a photoswitchable peptide tracked from picoseconds to microseconds by time-resolved IR spectroscopy170
Effects of an extract from Phyllanthus niruri on hepatitis B and woodchuck hepatitis viruses: in vitro and in vivo studies.170
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance170
Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein170
A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia–reperfusion injury170
Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled.170
The recovery of photosynthesis from low-temperature photoinhibition is accelerated by the unsaturation of membrane lipids: a mechanism of chilling tolerance.170
Purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from apple fruit.170
Global biodiversity loss from tropical deforestation170
Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication170
Cloning and expression of a protective antigen from the cattle tick Boophilus microplus.170
HLA-linked congenital adrenal hyperplasia results from a defective gene encoding a cytochrome P-450 specific for steroid 21-hydroxylation.170
Unusual cardioactive peptide (CCAP) from pericardial organs of the shore crab Carcinus maenas170
Bioconversion of chitin to chitosan: purification and characterization of chitin deacetylase from Mucor rouxii.170
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome169
Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotype169
Polyamines protect Escherichia coli cells from the toxic effect of oxygen169
Energy storage emerging: A perspective from the Joint Center for Energy Storage Research169
X-ray crystallographic and computational studies of the O 2 -tolerant [NiFe]-hydrogenase 1 from Escherichia coli169
Elimination of Borrelia burgdorferi from vector ticks feeding on OspA-immunized mice.169
Isolation of a Major Cell Surface Glycoprotein from Fibroblasts169
DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells169
Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass169
The conformation of the sarcin/ricin loop from 28S ribosomal RNA.169
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning168
Identification of H2N3 influenza A viruses from swine in the United States168
Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man168
Characterization and catalytic properties of the sterol 14α-demethylase from Mycobacterium tuberculosis168
Spatial interactions in human vision: from near to farvia experience-dependent cascades of connections.168
Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root168
Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: Evidence from genomic deletion of biosynthetic enzymes168
Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza virus neuraminidase.168
Opening protein pores with chaotropes enhances Fe reduction and chelation of Fe from the ferritin biomineral168
Estimating hydration changes upon biomolecular reactions from osmotic stress, high pressure, and preferential hydration experiments168
Unspeciated organic emissions from combustion sources and their influence on the secondary organic aerosol budget in the United States168
Phosphorylation of p47 phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxid168
Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.168
The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow.168
Biomolecular hydration: From water dynamics to hydrodynamics168
Improved herbivore resistance in cultivated tomato with the sesquiterpene biosynthetic pathway from a wild relative167
Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells167
Risk of collective failure provides an escape from the tragedy of the commons167
Five computational developability guidelines for therapeutic antibody profiling167
Spatially resolved metabolomics to discover tumor-associated metabolic alterations167
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa.167
Population-based 3D genome structure analysis reveals driving forces in spatial genome organization167
Attentional modulation of effective connectivity from V2 to V5/MT in humans167
Ab initio thermodynamics of liquid and solid water167
Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis167
Langerhans cells cross-present antigen derived from skin167
Direct conversion of an oligopeptide from a β-sheet to an α-helix: A model for amyloid formation167
COHESION OF DNA MOLECULES ISOLATED FROM PHAGE LAMBDA167
Integrative modeling of gene and genome evolution roots the archaeal tree of life167
Biophysical insight into mechanisms of sonoporation166
A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution166
Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from α,β-unsaturated aldehydes for enantioselective Diels–Alder reactions166
Peptide methionine sulfoxide reductase fromEscherichia coliandMycobacterium tuberculosisprotects bacteria against oxidative damage from reactive nitrogen intermediates166
Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling166
Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.166
Emerging role of wetland methane emissions in driving 21st century climate change166
Receptor-mediated glutamate release from volume sensitive channels in astrocytes166
Mammalian cytoplasmic actins are the products of at least two genes and differ in primary structure in at least 25 identified positions from skeletal muscle actins166
Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.166
AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses165
A second major native von Hippel–Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor165
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions165
Isolation of glycosaminoglycans (heparan sulfate) from glomerular basement membranes165
Improved saccharification and ethanol yield from field-grown transgenic poplar deficient in cinnamoyl-CoA reductase165
The Neandertal type site revisited: Interdisciplinary investigations of skeletal remains from the Neander Valley, Germany165
Flow enhances photosynthesis in marine benthic autotrophs by increasing the efflux of oxygen from the organism to the water165
Purification of ras GTPase activating protein from bovine brain.165
Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice165
Cleistogamous flowering in barley arises from the suppression of microRNA-guided HvAP2 mRNA cleavage165
Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor.165
Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria165
Leptosphaeria rhodopsin: Bacteriorhodopsin-like proton pump from a eukaryote165
Characterization and distribution of nucleic acid sequences of a novel type C retrovirus isolated from neoplastic human T lymphocytes.164
Monitoring molecular dynamics using coherent electrons from high harmonic generation164
Two terrestrial records of rapid climatic change during the glacial–Holocene transition (14,000– 9,000 calendar years B.P.) from Europe164
Surface attachment induces Pseudomonas aeruginosa virulence164
Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress164
A study of problems encountered in Granger causality analysis from a neuroscience perspective164
Intrinsic β-sheet propensities result from van der Waals interactions between side chains and the local backbone164
Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome164
Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors164
Three forms of gonadotropin-releasing hormone characterized from brains of one species.164
The generation and propagation of the human alpha rhythm164
A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.164
Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows164
Adaptation to herbivory by the Tammar wallaby includes bacterial and glycoside hydrolase profiles different from other herbivores164
Insights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta)163
A Legionella pneumophila -translocated substrate that is required for growth within macrophages and protection from host cell death163
Cloning the interleukin 1 receptor from human T cells.163
N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage163
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects163
Diversifying livestock promotes multidiversity and multifunctionality in managed grasslands163
Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis.163
Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.163
Influenza A virus-generated small RNAs regulate the switch from transcription to replication163
Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells163
The dorsal anterior cingulate cortex is selective for pain: Results from large-scale reverse inference163
Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability.163
The plastid ndh genes code for an NADH-specific dehydrogenase: Isolation of a complex I analogue from pea thylakoid membranes163
Crystal structure of the photosensing module from a red/far-red light-absorbing plant phytochrome163
Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides163
Impacts of climate change on future air quality and human health in China163
Evidence for keratinocyte stem cells in vitro : Long term engraftment and persistence of transgene expression from retrovirus-transduced keratinocytes162
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides162
Identification, purification, and functional reconstitution of the cyclic GMP-dependent channel from rod photoreceptors.162
Chemical synthesis gets a fillip from molecular recognition and self-assembly processes162
Microbial denitrification dominates nitrate losses from forest ecosystems162
Evolution of an enzyme activity: crystallographic structure at 2-A resolution of cephalosporinase from the ampC gene of Enterobacter cloacae P99 and comparison with a class A penicillinase.162
Solution NMR structure of the major cold shock protein (CspA) from Escherichia coli: identification of a binding epitope for DNA.162
Expression of the antiproliferative gene TIS21 at the onset of neurogenesis identifies single neuroepithelial cells that switch from proliferative to neuron-generating division162
A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection.162
Aggressive behavior induces release of nerve growth factor from mouse salivary gland into the bloodstream.162
FM1-43 dye ultrastructural localization in and release from frog motor nerve terminals.162
De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture162
CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas162
Hole hopping through tyrosine/tryptophan chains protects proteins from oxidative damage162
Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses162
Purification and molecular cloning of an inducible gram-negative bacteria-binding protein from the silkworm, Bombyx mori.162
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes162
Infectious RNA transcribed from stably cloned full-length cDNA of dengue type 4 virus.162
Remarkable variation in maize genome structure inferred from haplotype diversity at the bz locus162
Defining a new nomenclature for the structures of active and inactive kinases162
Universal brain signature of proficient reading: Evidence from four contrasting languages162
A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.162
Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B.162
In Vitro Formation of Assimilatory Reduced Nicotinamide Adenine Dinucleotide Phosphate: Nitrate Reductase from a Neurospora Mutant and a Component of 161
Phloem sap proteins from Cucurbita maxima and Ricinus communis have the capacity to traffic cell to cell through plasmodesmata161
Electrostatic steering and ionic tethering in enzyme–ligand binding: Insights from simulations161
Lessons from the past: Evolutionary impacts of mass extinctions161
Increased mRNA levels for components of the lysosomal, Ca2+-activated, and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients.161
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na+] and pH but elevated viscosity161
Purification and characterization of acidic fibroblast growth factor from bovine brain.161
Balancing trade-offs between biotic and abiotic stress responses through leaf age-dependent variation in stress hormone cross-talk161
Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus161
Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing161
Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation161
Zinc transfer from transcription factor IIIA fingers to thionein clusters.161
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype161
REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus160
Proteins from Plant Cell Walls Inhibit Polygalacturonases Secreted by Plant Pathogens160
Interpreting contemporary trends in atmospheric methane160
Bizarre tRNAs inferred from DNA sequences of mitochondrial genomes of nematode worms.160
From basic network principles to neural architecture: emergence of orientation columns.160
Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it.160
Dendritic cell targeting ofBacillus anthracisprotective antigen expressed byLactobacillus acidophilusprotects mice from lethal challenge160
CooA, a CO-sensing transcription factor from Rhodospirillum rubrum , is a CO-binding heme protein160
Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A.160
A multifunctional shape-morphing elastomer with liquid metal inclusions160
Cattle ranching intensification in Brazil can reduce global greenhouse gas emissions by sparing land from deforestation160
Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol159
Rescue of the defective genome of Moloney sarcoma virus from a noninfectious hamster tumor and the production of pseudotype sarcoma viruses with various murine leukemia viruses.159
Simulating tactile signals from the whole hand with millisecond precision159
A hemoglobin from plants homologous to truncated hemoglobins of microorganisms159
Insect olfaction from model systems to disease control159
Protein conjugates of synthetic saccharides elicit higher levels of serum IgG lipopolysaccharide antibodies in mice than do those of the O-specific polysaccharide fromShigella dysenteriaetype 1159
Simplified mechanism for new particle formation from methanesulfonic acid, amines, and water via experiments and ab initio calculations159
Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel.159
Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: a periplasmic homolog of cyclophilin that is not inhibited by cyclosporin A.159
A presenilin dimer at the core of the γ-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis159
Extranuclear protection of chromosomal DNA from oxidative stress159
Physicochemical characterization of a ouabain isomer isolated from bovine hypothalamus.159
3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine.159
Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744.159
The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice158
Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides.158
In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme158
Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli.158
Distinct size distribution of endogenous siRNAs in maize: Evidence from deep sequencing in the mop1-1 mutant158
Disruption of the neural response to rapid acoustic stimuli in dyslexia: Evidence from functional MRI158
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius158
Large-scale production of functional human serum albumin from transgenic rice seeds158
Amino acid sequence of rabbit fast-twitch skeletal muscle calsequestrin deduced from cDNA and peptide sequencing.158
The pseudopterosins: anti-inflammatory and analgesic natural products from the sea whip Pseudopterogorgia elisabethae.158
Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia157
Floral homeotic genes were recruited from homologous MADS-box genes preexisting in the common ancestor of ferns and seed plants157
Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia.157
Changes in mitochondrial genetic codes as phylogenetic characters: Two examples from the flatworms157
Replicated evolution of trophic specializations in an endemic cichlid fish lineage from Lake Tanganyika157
STUDIES ON THE COMPOSITION OF THE PROTEIN FROM ESCHERICHIA COLI RIBOSOMES157
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S -adenosyl- l -methionine157
Evolution of the avian sex chromosomes from an ancestral pair of autosomes157
Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones157
Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog.157
Complete amino acid sequence of alpha-tubulin from porcine brain.157
From basic network principles to neural architecture: emergence of orientation-selective cells.157
Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling157
The human sex ratio from conception to birth157
Regulation of protein synthesis in reticulocyte lysates: phosphorylation of methionyl-tRNAf binding factor by protein kinase activity of translational inhibitor isolated from hemedeficient lysates.157
Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells.157
Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae.157
Protection from nitrosative stress by yeast flavohemoglobin157
Gene transfer from organelles to the nucleus: Frequent and in big chunks157
Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1 α -dependent156
Candidate phylum TM6 genome recovered from a hospital sink biofilm provides genomic insights into this uncultivated phylum156
Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket156
The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat156
SpoIIAB is an anti-sigma factor that binds to and inhibits transcription by regulatory protein sigma F from Bacillus subtilis.156
A CHANGE FROM NONSENSE TO SENSE IN THE GENETIC CODE156
Genome-wide effects on Escherichia coli transcription from ppGpp binding to its two sites on RNA polymerase156
CD4+T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: Association with NY-ESO-1 antibody production156
Semipermeable species boundaries between Anopheles gambiae and Anopheles arabiensis : Evidence from multilocus DNA sequence variation156
A ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO)-like protein from Chlorobium tepidum that is involved with sulfur metabolism and the response to oxidative st156
Primary structure of the gamma-carboxyglutamic acid-containing protein from bovine bone.156
Massively parallel screening of synthetic microbial communities156
Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast156
Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration.156
Evidence for social working memory from a parametric functional MRI study156
Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors.156
Mixed-power scaling of whole-plant respiration from seedlings to giant trees155
Independent and combined analyses of sequences from all three genomic compartments converge on the root of flowering plant phylogeny155
Direct measurements of methane emissions from abandoned oil and gas wells in Pennsylvania155
The Xanthomonas Hrp type III system secretes proteins from plant and mammalian bacterial pathogens155
Purification and characterization of a soluble salicylic acid-binding protein from tobacco.155
Evidence for indigenous nitrogen in sedimentary and aeolian deposits from the Curiosity rover investigations at Gale crater, Mars155
Dietary changes of large herbivores in the Turkana Basin, Kenya from 4 to 1 Ma155
Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies.155
Population robustness arising from cellular heterogeneity155
Notch signaling in the development of the inner ear: Lessons from Drosophila155
A receptor tyrosine kinase from choanoflagellates: Molecular insights into early animal evolution155
The uncertain climate footprint of wetlands under human pressure155
ATG9 regulates autophagosome progression from the endoplasmic reticulum in Arabidopsis155
The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection155
Associations between early life adversity and executive function in children adopted internationally from orphanages155
Localizing proteins in the cell from their phylogenetic profiles155
How cholesterol stiffens unsaturated lipid membranes155
From icy roads to salty streams154
How the regulatory protein, IF 1 , inhibits F 1 -ATPase from bovine mitochondria154
RELEASE OF NEWLY SYNTHESIZED DOPAMINE FROM DOPAMINE-CONTAINING TERMINALS IN THE STRIATUM OF THE RAT154
Nanopatterned protein microrings from a diatom that direct silica morphogenesis154
Interactions between photoexcited rhodopsin and GTP-binding protein: kinetic and stoichiometric analyses from light-scattering changes.154
Directional cloning of DNA fragments at a large distance from an initial probe: a circularization method.154
Isolation and characterization of the inositol trisphosphate receptor from smooth muscle.154
Language from police body camera footage shows racial disparities in officer respect154
NADPH oxidase is an O 2 sensor in airway chemoreceptors: Evidence from K + current modulation in wild-type and oxidase-deficient m154
Where does biodiversity go from here? A grim business-as-usual forecast and a hopeful portfolio of partial solutions154
Multiple calcium channels mediate neurotransmitter release from peripheral neurons.154
Endogenous lectins from cultured cells: nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblasts.153
RNase P RNAs from some Archaea are catalytically active153
Avoiding the pitfalls of single particle cryo-electron microscopy: Einstein from noise153
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer153
Cosmogenic nuclide dating of Sahelanthropus tchadensis and Australopithecus bahrelghazali : Mio-Pliocene hominids from Chad153
Assembling the glycopeptide antibiotic scaffold: The biosynthesis of from Streptomyces toyocaensis NRRL15009153
A membrane-associated thioredoxin required for plant growth moves from cell to cell, suggestive of a role in intercellular communication153
Proteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillata153
A singular enzymatic megacomplex from Bacillus subtilis153
Iron acquisition from heme and hemoglobin by a Serratia marcescens extracellular protein.153
Multimodal gradients across mouse cortex153
The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals153
Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum153
ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells153
A phytochrome from the fern Adiantum with features of the putative photoreceptor NPH1153
In Vitro Induction of Granulocyte Differentiation in Hematopoietic Cells from Leukemic and Non-Leukemic Patients153
A host-inducible cytochrome P-450 from a host-specific caterpillar: molecular cloning and evolution.153
Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance153
Biogeographic and evolutionary implications of a diverse paleobiota in amber from the early Eocene of India153
MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis153
Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells.153
Higher-order assembly of microtubules by counterions: From hexagonal bundles to living necklaces153
Illusory contours activate specific regions in human visual cortex: evidence from functional magnetic resonance imaging.152
Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X152
Identification and analysis of recombineering functions from Gram-negative and Gram-positive bacteria and their phages152
Liquid–liquid phase transition in compressed hydrogen from first-principles simulations152
Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians152
Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli152
Pulmonary surfactant and its components inhibit secretion of phosphatidylcholine from cultured rat alveolar type II cells.152
Excretion of hepatitis B surface antigen particles from mouse cells transformed with cloned viral DNA.152
Constructing primate phylogenies from ancient retrovirus sequences152
Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis152
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges152
An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide152
Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila152
Cerebellar vermis is a target of projections from the motor areas in the cerebral cortex152
DNA nanostructures coordinate gene silencing in mature plants152
The oncofetal domain of fibronectin defined by monoclonal antibody FDC-6: its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma.152
Horizontal gene transfer from flowering plants to Gnetum151
A different function for a member of an ancient and highly conserved cytochrome P450 family: From essential sterols to plant defense151
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk151
Circadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro.151
Evidence for recent, population-specific evolution of the human mutation rate151
Penicillin-resistant viridans streptococci have obtained altered penicillin-binding protein genes from penicillin-resistant strains of Streptococcus pneumoniae.151
Vesicle formation from the nuclear membrane is induced by coexpression of two conserved herpesvirus proteins151
Isolation of a 7S particle from Xenopus laevis oocytes: a 5S RNA-protein complex.151
Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure151
Highway proximity and black carbon from cookstoves as a risk factor for higher blood pressure in rural China151
Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position151
Changes in cognitive flexibility and hypothesis search across human life history from childhood to adolescence to adulthood150
Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor.150
Surface exposure to sunlight stimulates CO 2 release from permafrost soil carbon in the Arctic150
cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization.150
Half-century evidence from western Canada shows forest dynamics are primarily driven by competition followed by climate150
Viscosity of deeply supercooled water and its coupling to molecular diffusion150
Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity150
Suppression of HIV-specific T cell activity by lymph node CD25 + regulatory T cells from HIV-infected individuals150
Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells150
Nutrition, immunity and infection: From basic knowledge of dietary manipulation of immune responses to practical application of ameliorating suffering and improving survival150
Viruses from extreme thermal environments150
Differences in spawning date between populations of common frog reveal local adaptation150
Paleobiology and comparative morphology of a late Neandertal sample from El Sidrón, Asturias, Spain150
Tomato Cf resistance proteins mediate recognition of cognate homologous effectors from fungi pathogenic on dicots and monocots150
Stable isotopes (δ 13 C and δ 15 N) of organic matrix from coral skeleton150
GroEL from the endosymbiont Buchnera aphidicola betrays the aphid by triggering plant defense150
Ferulate-5-hydroxylase from Arabidopsis thaliana defines a new family of cytochrome P450-dependent monooxygenases.150
Division of labor in honey bee gut microbiota for plant polysaccharide digestion150
Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.149
Neurotrophin secretion from hippocampal neurons evoked by long-term-potentiation-inducing electrical stimulation patterns149
Isolation and primary structure of two peptides with cardioacceleratory and hyperglycemic activity from the corpora cardiaca of Periplaneta americana.149
Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA149
Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.149
Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs149
Birds defend trees from herbivores in a Neotropical forest canopy149
Massive horizontal transfer of transposable elements in insects149
Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression.149
ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae149
Gambicin: A novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae149
Identification of a distinct soluble subunit of an intermediate filament protein: tetrameric vimentin from living cells.149
The ensemble folding kinetics of protein G from an all-atom Monte Carlo simulation149
Majority of CD4 + T cells from peripheral blood of HIV-1–infected individuals contain only one HIV DNA molecule149
Bradykinin inhibits M current via phospholipase C and Ca 2+ release from IP 3 -sensitive Ca 2+ 149
Ocean-wide tracking of pelagic sharks reveals extent of overlap with longline fishing hotspots149
Atrial natriuretic peptide inhibits renin release from juxtaglomerular cells by a cGMP-mediated process.149
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury148
Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress148
Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint ( Mentha x piperita , L.) that produces the aphi148
Avicins: Triterpenoid saponins from Acacia victoriae (Bentham) induce apoptosis by mitochondrial perturbation148
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins148
Growth of a pure population of mouse mast cells in vitro with conditioned medium derived from concanavalin A-stimulated splenocytes.148
From calcium blips to calcium puffs: Theoretical analysis of the requirements for interchannel communication148
A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia ( Da148
Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10.148
RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice.148
Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center.148
Variation in the molecular clock of primates148
Phytochrome from Agrobacterium tumefaciens has unusual spectral properties and reveals an N-terminal chromophore attachment site148
Disulfide Bond Dihedral Angles from Raman Spectroscopy148
Intake and transformation to a glycoside of ( Z )-3-hexenol from infested neighbors reveals a mode of plant odor reception and defense148
Abundant microsatellite polymorphism in Saccharomyces cerevisiae , and the different distributions of microsatellites in eight prokaryotes and S. cerevisi148
Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.148
Prediction of protein folding rates from the amino acid sequence-predicted secondary structure148
Multiple Common Properties of Human β 2 -Microglobulin and the Common Portion Fragment Derived from HL-A Antigen Molecules148
Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations148
Methylated simian virus 40-specific RNA from nuclei and cytoplasm of infected BSC-1 cells.147
A fully resolved backbone phylogeny reveals numerous dispersals and explosive diversifications throughout the history of Asteraceae147
Cloning and expression of a distinctive class of self-incompatibility (S) gene from Papaver rhoeas L.147
In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses147
Isolation of a hepadnavirus from the woolly monkey, a New World primate147
An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter147
Malaria parasite exit from the host erythrocyte: A two-step process requiring extraerythrocytic proteolysis147
From symmetry to asymmetry: Phylogenetic patterns of asymmetry variation in animals and their evolutionary significance147
Improving nanopore read accuracy with the R2C2 method enables the sequencing of highly multiplexed full-length single-cell cDNA147
Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7–induced signaling147
Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum.147
A genetic defect in the biosynthesis of dermatan sulfate proteoglycan: galactosyltransferase I deficiency in fibroblasts from a patient with a progeroid syndrome.147
Dynamic reorientation of cortical microtubules, from transverse to longitudinal, in living plant cells.147
Nuclear localization signal binding protein from Arabidopsis mediates nuclear import of Agrobacterium VirD2 protein147
Isolation of a nonmitogenic angiogenesis factor from wound fluid.147
Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy147
Atomic-level characterization of protein–protein association147
Knock-out mutants from an En-1 mutagenized Arabidopsis thaliana population generate phenylpropanoid biosynthesis phenotypes147
A collaborative multiyear, multimodel assessment of seasonal influenza forecasting in the United States147
Compartmentation protects trypanosomes from the dangerous design of glycolysis147
Kynurenine as an Intermediate in the Formation of Nicotinic Acid from Tryptophane by Neurospora147
Crystal structure of heat shock locus V (HslV) from Escherichia coli147
Protein complexing in a methanogen suggests electron bifurcation and electron delivery from formate to heterodisulfide reductase146
Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity146
Insulin-like growth factor I accelerates recovery from ischemic acute tubular necrosis in the rat.146
Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution146
Tropospheric winds from northeastern China carry the etiologic agent of Kawasaki disease from its source to Japan146
Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries.146
Divergent trends of open-surface water body area in the contiguous United States from 1984 to 2016146
High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses146
Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis146
GABAergic feedforward projections from the inferior colliculus to the medial geniculate body.146
Expanding protein universe and its origin from the biological Big Bang146
Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides146
Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors.146
Human multipotent stromal cells from bone marrow and microRNA: Regulation of differentiation and leukemia inhibitory factor expression146
Characterization of Prochlorococcus clades from iron-depleted oceanic regions146
Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST–REST complex146
Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair146
Phylogenetic, functional, and taxonomic richness have both positive and negative effects on ecosystem multifunctionality146
Antibody-based assay discriminates Zika virus infection from other flaviviruses146
Modeling gene regulation from paired expression and chromatin accessibility data145
Meteorite-catalyzed syntheses of nucleosides and of other prebiotic compounds from formamide under proton irradiation145
Direct chemical evidence for eumelanin pigment from the Jurassic period145
Mechanisms of adhesion among cells from neural tissues of the chick embryo.145
A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis.145
Differential effect of alpha-latrotoxin on exocytosis from small synaptic vesicles and from large dense-core vesicles containing calcitonin gene-related peptide at the frog neuromuscular junction.145
Exoplanet orbital eccentricities derived from LAMOST–Kepler analysis145
Breed distribution and history of canine mdr1-1Δ , a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage145
Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957145
A universal picture of chromophores in π-conjugated polymers derived from single-molecule spectroscopy145
Hydrogen production from inexhaustible supplies of fresh and salt water using microbial reverse-electrodialysis electrolysis cells145
Limits to the world’s green water resources for food, feed, fiber, timber, and bioenergy145
SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer145
A Xenopus oocyte β subunit: Evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit145
Gene flow from North Africa contributes to differential human genetic diversity in southern Europe145
Emergence of antibiotic resistance from multinucleated bacterial filaments145
Self-assembly of a heteroduplex helicate from two different ligand strands and Cu(II) cations.145
Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma145
Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus144
Mechanism of transfer of NO from extracellular S -nitrosothiols into the cytosol by cell-surface protein disulfide isomerase144
Correlations in ion channel expression emerge from homeostatic tuning rules144
Global reconstruction of historical ocean heat storage and transport144
Proteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties144
Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmo144
Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum : Thermostability and electron transfer144
Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria144
Wind farm power optimization through wake steering144
XAX1 from glycosyltransferase family 61 mediates xylosyltransfer to rice xylan144
Radiocarbon dates from the Grotte du Renne and Saint-Césaire support a Neandertal origin for the Châtelperronian144
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition144
Two-dimensional analysis of flagellar proteins from wild-type and paralyzed mutants of Chlamydomonas reinhardtii.144
Species realities and numbers in sexual vertebrates: Perspectives from an asexually transmitted genome144
In situ isolation of mRNA from individual plant cells: creation of cell-specific cDNA libraries.144
Impact of climate change on New York City’s coastal flood hazard: Increasing flood heights from the preindustrial to 2300 CE143
Double-stranded RNA under force and torque: Similarities to and striking differences from double-stranded DNA143
A metallothionein containing a zinc finger within a four-metal cluster protects a bacterium from zinc toxicity143
Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible ( E )-α-bisabolene synthase from grand fir ( 143
The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals143
Benzoic acid 2-hydroxylase, a soluble oxygenase from tobacco, catalyzes salicylic acid biosynthesis.143
Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome143
Surface multiheme c -type cytochromes from Thermincola potens and implications for respiratory metal reduction by Gram-positive bacteria143
A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway143
Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli143
Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.143
Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system143
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.143
Nootropic α7 nicotinic receptor allosteric modulator derived from GABA A receptor modulators143
Cysteine protease inhibitors as chemotherapy: Lessons from a parasite target143
HMf, a DNA-binding protein isolated from the hyperthermophilic archaeon Methanothermus fervidus, is most closely related to histones.143
Insertional mutagenesis and marker rescue in a protozoan parasite: cloning of the uracil phosphoribosyltransferase locus from Toxoplasma gondii.143
Predicting Social Security numbers from public data143
Reconstitution of a protein translocation system containing purified SecY, SecE, and SecA from Escherichia coli.142
Marker succession during the development of keratinocytes from cultured human embryonic stem cells142
Identity of a second type of allatostatin from cockroach brains: an octadecapeptide amide with a tyrosine-rich address sequence.142
Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus142
Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells142
Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors.142
Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma142
Isolation, Structure, and Absolute Configuration of a New Natural Insect Juvenile Hormone from Manduca sexta142
Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells142
The x-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale142
Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae142
Activating transcription from single stranded DNA.142
Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory142
From seed germination to flowering, light controls plant development via the pigment phytochrome.142
Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor.142
An Early Pleistocene hominin mandible from Atapuerca-TD6, Spain141
Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid141
Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP.141
Origins of coevolution between residues distant in protein 3D structures141
Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from  Xenopus  oocytes141
Heat shock protein hsp70 protects cells from thermal stress even after deletion of its ATP-binding domain.141
Characterization of recombinant phytochrome from the cyanobacterium  Synechocystis141
Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis141
What grades and achievement tests measure141
Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1141
Suboptimal SARS-CoV-2−specific CD8 + T cell response associated with the prominent HLA-A*02:01 phenotype141
Exosomes regulate neurogenesis and circuit assembly141
cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.140
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.140
Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan140
Vectorial discharge of peptides released by puromycin from attached ribosomes.140
Dynamic brain network reconfiguration as a potential schizophrenia genetic risk mechanism modulated by NMDA receptor function140
Recruitment of a penicillin-binding protein gene from Neisseria flavescens during the emergence of penicillin resistance in Neisseria meningitidis.140
Explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa140
Dynamics of unbinding of cell adhesion molecules: Transition from catch to slip bonds140
Hydrogenotrophic methanogenesis in archaeal phylum Verstraetearchaeota reveals the shared ancestry of all methanogens140
Discovery of a selective Na V 1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models140
The persisting (P) cell: histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells.140
Body plan evolution of ascomycetes, as inferred from an RNA polymerase II phylogeny140
Three-dimensional structure of the "long" neurotoxin from cobra venom.140
Nitrogen management is essential to prevent tropical oil palm plantations from causing ground-level ozone pollution140
Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization139
NMR characterization of altered lignins extracted from tobacco plants down-regulated for lignification enzymes cinnamylalcohol dehydrogenase and cinnamoyl-CoA reductase139
Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF139
Isolation and identification of a diuretic hormone from the tobacco hornworm, Manduca sexta139
Isolation and characterization of the alpha-sialyl-beta-2,3-galactosyl-specific adhesin from fimbriated Escherichia coli.139
Biosynthesis of delta-aminolevulinic acid from the intact carbon skeleton of glutamic acid in greening barley.139
Predicting perturbation patterns from the topology of biological networks139
Effective connectivity changes in LSD-induced altered states of consciousness in humans139
Rapid acquisition and model-based analysis of cell-free transcription–translation reactions from nonmodel bacteria139
Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.139
Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution139
Laser capture microdissection analysis of gene expression in macrophages from atherosclerotic lesions of apolipoprotein E-deficient mice139
A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.139
Embryo implantation evolved from an ancestral inflammatory attachment reaction139
Vitamin D3 binding protein (group-specific component) is a precursor for the macrophage-activating signal factor from lysophosphatidylcholine-treated lymphocytes.139
High pressure fosters protein refolding from aggregates at high concentrations139
Diagnosis of prostate cancer by desorption electrospray ionization mass spectrometric imaging of small metabolites and lipids139
A tick-borne segmented RNA virus contains genome segments derived from unsegmented viral ancestors139
Conversion from CUL4-based COP1–SPA E3 apparatus to UVR8–COP1–SPA complexes underlies a distinct biochemical function of COP1 under UV-B139
Characterization of a unique [FeS] cluster in the electron transfer chain of the oxygen tolerant [NiFe] hydrogenase from Aquifex aeolicus139
Learning from episodes of degradation and recovery in variable Australian rangelands139
Covalent modification of the iron protein of nitrogenase from Rhodospirillum rubrum by adenosine diphosphoribosylation of a specific arginine residue.139
Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid139
Mitotic factors from mammalian cells induce germinal vesicle breakdown and chromosome condensation in amphibian oocytes.139
Projected Atlantic hurricane surge threat from rising temperatures139
Phylogeny from function: evidence from the molecular fossil record that tRNA originated in replication, not translation.138
Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes from Mycobacterium tuberculosis138
Gravity of human impacts mediates coral reef conservation gains138
Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.138
Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer138
Artificial evolution extends the spectrum of viruses that are targeted by a disease-resistance gene from potato138
EXTRACTION OF COLLAGEN FROM CONNECTIVE TISSUE BY NEUTRAL SALT SOLUTIONS138
Fat, weather, and date affect migratory songbirds’ departure decisions, routes, and time it takes to cross the Gulf of Mexico138
The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.138
Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARβ/δ to RAR138
Smoke-derived karrikin perception by the α/β-hydrolase KAI2 from Arabidopsis138
The structural basis of myotonic dystrophy from the crystal structure of CUG repeats138
l -Tartaric acid synthesis from vitamin C in higher plants138
Automated prediction of protein function and detection of functional sites from structure138
The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response138
Amplification of DNA from preserved specimens shows blowflies were preadapted for the rapid evolution of insecticide resistance138
Molecular cloning and heterologous expression of a cDNA encoding berbamunine synthase, a C--O phenol-coupling cytochrome P450 from the higher plant Berberis stolonifera.138
Mindfulness training reduces loneliness and increases social contact in a randomized controlled trial138
Scalable production of mechanically tunable block polymers from sugar138
The chimeric eukaryote: Origin of the nucleus from the karyomastigont in amitochondriate protists138
Molecular characterization of NAD:arginine ADP-ribosyltransferase from rabbit skeletal muscle.138
Nonprotein Amino Acids from Spark Discharges and Their Comparison with the Murchison Meteorite Amino Acids137
Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion137
Mode of action uncovered for the specific reduction of methane emissions from ruminants by the small molecule 3-nitrooxypropanol137
Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China137
Amino acid sequence of the plasma membrane ATPase of Neurospora crassa: deduction from genomic and cDNA sequences.137
Isolation of cDNAs encoding guanine nucleotide-binding protein beta-subunit homologues from maize (ZGB1) and Arabidopsis (AGB1).137
Evidence for a lipoprotein carrier in human plasma catalyzing sterol efflux from cultured fibroblasts and its relationship to lecithin:cholesterol acyltransferase.137
Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells137
Global increase in DNA methylation during orange fruit development and ripening137
Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort137
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury137
Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes.137
How cuckoldry can decrease the opportunity for sexual selection: Data and theory from a genetic parentage analysis of the sand goby, Pomatoschistus minutus137
Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse137
Differences among 100-A filamentilament subunits from different cell types.137
Dopamine modulates the reward experiences elicited by music137
Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts137
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae137
Insight into the PrP C → PrP Sc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants137
In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation137
Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP137
An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors136
Selection of functional T cell receptor mutants from a yeast surface-display library136
Baseline intrinsic flammability of Earth’s ecosystems estimated from paleoatmospheric oxygen over the past 350 million years136
Expression cloning in yeast of a cDNA encoding a broad specificity amino acid permease from Arabidopsis thaliana.136
Evidence from molecular systematics for decreased avian diversification in the pleistocene Epoch.136
Disentangling the role of photosynthesis and stomatal conductance on rising forest water-use efficiency136
Factors associated with the diversification of the gut microbial communities within chimpanzees from Gombe National Park136
Venezuelan equine encephalitis emergence: Enhanced vector infection from a single amino acid substitution in the envelope glycoprotein136
In vivo uptake of chylomicron [3H]retinyl ester by rat liver: evidence for retinol transfer from parenchymal to nonparenchymal cells.136
Insights into transcriptional regulation and σ competition from an equilibrium model of RNA polymerase binding to DNA136
Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene.136
Diapause in the mosquito Culex pipiens evokes a metabolic switch from blood feeding to sugar gluttony136
Light Chains of Myosins from White, Red, and Cardiac Muscles136
Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers.136
New Method to Prepare N-t -Butoxycarbonyl Derivatives and the Corresponding Sulfur Analogs from di- t -Butyl Dicarbonate or di- 136
Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes136
Cloning and identification of an oxytocin/vasopressin-like receptor and its ligand from insects136
In vitro maturation of mesencephalic dopaminergic neurons from mouse embryos is enhanced in presence of their striatal target cells.136
Polyproline II propensities from GGXGG peptides reveal an anticorrelation with β-sheet scales136
Release of calcium from stores alters the morphology of dendritic spines in cultured hippocampal neurons136
Regulation of Heat Loss from the Human Body136
Release from quiescence of CD34+ CD38- human umbilical cord blood cells reveals their potentiality to engraft adults.136
RNA-controlled polymorphism in the in vivo assembly of 180-subunit and 120-subunit virions from a single capsid protein136
SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma135
Amplification–mutagenesis: Evidence that “directed” adaptive mutation and general hypermutability result from growth with a selected gene amplification135
Preferential cooling of hot extremes from cropland albedo management135
Causes of natural variation in fitness: Evidence from studies of Drosophila populations135
CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages135
Catalytic amino acid production from biomass-derived intermediates135
Apparent homology of expressed genes from wood-forming tissues of loblolly pine ( Pinus taeda L.) with Arabidopsis thaliana135
Molecular cloning of a cytochrome P450 taxane 10β-hydroxylase cDNA from Taxus and functional expression in yeast135
High-resolution protein complexes from integrating genomic information with molecular simulation135
What might we learn from climate forecasts?135
Breeding signatures of rice improvement revealed by a genomic variation map from a large germplasm collection135
Isolation of the opioid heptapeptide Met-enkephalin [Arg6,Phe7] from bovine adrenal medullary granules and striatum.135
Additional antitumor ecteinascidins from a Caribbean tunicate: crystal structures and activities in vivo.135
AN ATP-DEPENDENT DEOXYRIBONUCLEASE FROM Escherichia coli WITH A POSSIBLE ROLE IN GENETIC RECOMBINATION135
Governing the recreational dimension of global fisheries135
Obligately barophilic bacterium from the Mariana trench.134
Association between medical cannabis laws and opioid overdose mortality has reversed over time134
Critical roles of soluble starch synthase SSIIIa and granule-bound starch synthase Waxy in synthesizing resistant starch in rice134
Comprehensive comparison of pore-scale models for multiphase flow in porous media134
Elimination of ergovaline from a grass– Neotyphodium endophyte symbiosis by genetic modification of the endophyte134
Human papillomavirus DNA in cutaneous primary and metastasized squamous cell carcinomas from patients with epidermodysplasia verruciformis.134
Functional expression and subcellular localization of an anion exchanger cloned from choroid plexus.134
Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins.134
A protein kinase from Xenopus eggs specific for ribosomal protein S6.134
Solving matrix equations in one step with cross-point resistive arrays134
Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity134
Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.134
Primary structure of a beta subunit ofalpha-dendrotoxin-sensitive K+ channels from bovine brain.134
From cell death to embryo arrest: Mathematical models of human preimplantation embryo development134
Coated vesicles transport newly synthesized membrane glycoproteins from endoplasmic reticulum to plasma membrane in two successive stages.134
Evidence from ammonoids and conodonts for multiple Early Triassic mass extinctions134
OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes134
Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements134
Drivers of change in China’s energy-related CO 2 emissions134
Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain.134
In vitro reconstitution and steady-state analysis of the fatty acid synthase from Escherichia coli133
An early modern human from Tianyuan Cave, Zhoukoudian, China133
The Three Dimensional Structure of the Lysozyme from Bacteriophage T4133
Dynamic reorganization of human resting-state networks during visuospatial attention133
Exposure to ambient black carbon derived from a unique inventory and high-resolution model133
Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids.133
Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain.133
Stereospecific inositol 1,4,5-[32P]trisphosphate binding to isolated rat liver nuclei: evidence for inositol trisphosphate receptor-mediated calcium release from the nucleus.133
Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism133
Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium.133
Evolution of the primate lineage leading to modern humans: Phylogenetic and demographic inferences from DNA sequences133
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain133
Specificity and robustness of long-distance connections in weighted, interareal connectomes133
Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex133
Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.133
Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL.133
Crystal structures of γ-glutamyltranspeptidase from Escherichia coli , a key enzyme in glutathione metabolism, and its reaction intermediate133
Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus.133
Increased nutritive value of transgenic potato by expressing a nonallergenic seed albumin gene from Amaranthus hypochondriacus133
Purification of the saxitoxin receptor of the sodium channel from rat brain.133
Social behavior for autonomous vehicles133
On the future of transportation in an era of automated and autonomous vehicles133
Two-step pathway for isoprenoid synthesis133
Peptide adsorption on a hydrophobic surface results from an interplay of solvation, surface, and intrapeptide forces133
Sonic hedgehog and retinoic acid synergistically promote sensory fate specification from bone marrow-derived pluripotent stem cells133
Chaperone-dependent amyloid assembly protects cells from prion toxicity133
Isolation and characterization of Staufen-containing ribonucleoprotein particles from rat brain132
Primary structure of the L subunit of the reaction center from Rhodopseudomonas sphaeroides.132
Programmed loss of millions of base pairs from a vertebrate genome132
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals.132
Transfer of oxygen from an artificial protease to peptide carbon during proteolysis.132
Mouse and human urothelial cancer organoids: A tool for bladder cancer research132
Primary structure of elongation factor Tu from Escherichia coli.132
Carbon dioxide sources from Alaska driven by increasing early winter respiration from Arctic tundra132
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells132
Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element.132
Ice as a matrix for IR-matrix-assisted laser desorption/ionization: mass spectra from a protein single crystal.132
Initial events in the formation of neuromuscular synapse: rapid induction of acetylcholine release from embryonic neuron.132
Decoding moral judgments from neural representations of intentions132
The state of magnesium in cells as estimated from the adenylate kinase equilibrium.132
The changing career trajectories of new parents in STEM132
Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2132
Pygmoid Australomelanesian Homo sapiens skeletal remains from Liang Bua, Flores: Population affinities and pathological abnormalities132
Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate fraction of a lymphoma cell line.132
Neurotensin: specific binding to synaptic membranes from rat brain.132
Hypoxia suppresses conversion from proliferative arrest to cellular senescence132
Taste receptor cells arise from local epithelium, not neurogenic ectoderm.132
GLYCOGEN SYNTHESIS FROM GLUCOSE, GLUCOSE-6-PHOSPHATE, AND URIDINE DIPHOSPHATE GLUCOSE IN MUSCLE PREPARATIONS132
Cytochalasin B: Effect on Lysosomal Enzyme Release from Human Leukocytes132
Coated vesicles from human placenta carry ferritin, transferrin, and immunoglobulin G.132
A rapid and label-free platform for virus capture and identification from clinical samples132
A high-coverage Neandertal genome from Chagyrskaya Cave132
In vitro system capable of differentiating fast Ca 2+ -triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release132
In vitro synthesis of selenocysteinyl-tRNA(UCA) from seryl-tRNA(UCA): involvement and characterization of the selD gene product.132
FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels131
An atmospheric p CO 2 reconstruction across the Cretaceous-Tertiary boundary from leaf megafossils131
UV light selectively coinduces supply pathways from primary metabolism and flavonoid secondary product formation in parsley131
The Nucleotide Sequence of the Lactose Messenger Ribonucleic Acid Transcribed from the UV5 Promoter Mutant of Escherichia coli131
More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells131
Indian annual ambient air quality standard is achievable by completely mitigating emissions from household sources131
Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort131
A PKR-like eukaryotic initiation factor 2α kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains131
The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis131
Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor.131
Direct transformation from amorphous to crystalline calcium phosphate facilitated by motif-programmed artificial proteins131
Metatranscriptomic reconstruction reveals RNA viruses with the potential to shape carbon cycling in soil131
Isolation of human T-cell lymphotropic virus type 2 from Guaymi Indians in Panama.131
Growing the terrestrial planets from the gradual accumulation of submeter-sized objects131
Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain.131
Tracking molecular evolution of photosynthesis by characterization of a major photosynthesis gene cluster from Heliobacillus mobilis131
Reconstitution of phospholipid translocase activity with purified Drs2p, a type-IV P-type ATPase from budding yeast131
Expert-level detection of acute intracranial hemorrhage on head computed tomography using deep learning131
Accelerating changes in ice mass within Greenland, and the ice sheet’s sensitivity to atmospheric forcing130
Subdiffusive motion of bacteriophage in mucosal surfaces increases the frequency of bacterial encounters130
Robust Hadley Circulation changes and increasing global dryness due to CO 2 warming from CMIP5 model projections130
Both GA2, GM2, and GD2 synthases and GM1b, GD1a, and GT1b synthases are single enzymes in Golgi vesicles from rat liver.130
Learning from lesions: patterns of tissue inflammation in leprosy.130
From phosphatases to vanadium peroxidases: A similar architecture of the active site130
A newly discovered cholesteryl galactoside from Borrelia burgdorferi130
Targeting pericyte–endothelial cell crosstalk by circular RNA-cPWWP2A inhibition aggravates diabetes-induced microvascular dysfunction130
Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically130
Identification of a G protein-coupled receptor for pheromone biosynthesis activating neuropeptide from pheromone glands of the moth Helicoverpa zea130
Amazonian functional diversity from forest canopy chemical assembly130
Partial purification of a lipoprotein with 5'-nucleotidase activity from membranes of rat liver cells.130
Daisy-chain gene drives for the alteration of local populations130
Do ultrastable proteins from hyperthermophiles have high or low conformational rigidity?130
Digital logic for soft devices130
Long noncoding RNA derived from CD244 signaling epigenetically controls CD8 + T-cell immune responses in tuberculosis infection130
Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat.130
T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells130
Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules130
Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units130
Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma130
Primary Dysbetalipoproteinemia: Predominance of a Specific Apoprotein Species in Triglyceride-Rich Lipoproteins129
CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing129
A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons.129
Evolution of modular intraflagellar transport from a coatomer-like progenitor129
Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium.129
The PR5K receptor protein kinase from Arabidopsis thaliana is structurally related to a family of plant defense proteins.129
From snapshot to movie: φ analysis of protein folding transition states taken one step further129
Structure of the glycosylphosphatidylinositol anchor of an arabinogalactan protein from Pyrus communis suspension-cultured cells129
From chemotaxis to the cognitive map: The function of olfaction129
Awakening: Predicting external stimulation to force transitions between different brain states129
Impact of adolescent marijuana use on intelligence: Results from two longitudinal twin studies129
Three globin lineages belonging to two structural classes in genomes from the three kingdoms of life129
An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190129
Regulatory changes in pterin and carotenoid genes underlie balanced color polymorphisms in the wall lizard129
Canine hemophilia B resulting from a point mutation with unusual consequences.129
N6 -methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle129
Nitric oxide mediates norepinephrine-induced prostaglandin E2 release from the hypothalamus.129
Sodium transport inhibitor from bovine hypothalamus.129
Quantum phase transition from triangular to stripe charge order in NbSe 2129
Deubiquitinating function of ataxin-3: Insights from the solution structure of the Josephin domain129
Engineering bone tissue from human embryonic stem cells129
Scientific communication in a post-truth society129
A Single Subunit from Avian Myeloblastosis Virus with Both RNA-Directed DNA Polymerase and Ribonuclease H Activity129
Piezo1 regulates mechanotransductive release of ATP from human RBCs129
Rescue of influenza B virus from eight plasmids128
Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer128
Sustainable water deliveries from the Colorado River in a changing climate128
The genetic basis of reproductive isolation: Insights from Drosophila128
Limits of long-term selection against Neandertal introgression128
Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade128
A parthenogenesis gene of apomict origin elicits embryo formation from unfertilized eggs in a sexual plant128
Binding of the cellulose-binding domain of exoglucanase Cex from Cellulomonas fimi to insoluble microcrystalline cellulose is entropically driven.128
Membrane curvature underlies actin reorganization in response to nanoscale surface topography128
Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum128
Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR128
Homospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved from deoxyhypusine synthase128
A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos.128
Production of medakafish chimeras from a stable embryonic stem cell line128
Melanin-dot–mediated delivery of metallacycle for NIR-II/photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy128
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart128
Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.128
Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct128
A conserved pattern of brain scaling from sharks to primates128
The Presence and Possible Role of Zinc in RNA Polymerase Obtained from Escherichia coli128
Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells.128
Synthesis of Globin Ribonucleic Acid from Duck-Reticulocyte Chromatin In Vitro128
Alkane biosynthesis by decarbonylation of aldehydes catalyzed by a particulate preparation from Pisum sativum.128
Isolation and amino acid sequence of a morphogenetic peptide from hydra128
Structural insights into FTO’s catalytic mechanism for the demethylation of multiple RNA substrates128
Delineating ecologically significant taxonomic units from global patterns of marine picocyanobacteria128
MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity128
Zinc- and iron-rubredoxins from Clostridium pasteurianum at atomic resolution: a high-precision model of a ZnS4 coordination unit in a protein.128
Sensitive detection of bacterial transcription initiation sites and differentiation from RNA processing sites in the pheromone-induced plasmid transfer system of Enterococcus faecalis.128
Sporulation-specific sigma factor sigma 29 of Bacillus subtilis is synthesized from a precursor protein, P31.128
Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers128
Voluntary exercise increases axonal regeneration from sensory neurons127
Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China127
Global imprint of mycorrhizal fungi on whole-plant nutrient economics127
Selective removal of apolipoprotein B-containing serum lipoproteins from blood plasma.127
A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9127
Astrocytes locally translate transcripts in their peripheral processes127
Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection127
Role of protein frame and solvent for the redox properties of azurin from Pseudomonas aeruginosa127
Overlooked roles of DNA damage and maternal age in generating human germline mutations127
Araceae from the Early Cretaceous of Portugal: Evidence on the emergence of monocotyledons127
Inactivating one hippocampus impairs avoidance of a stable room-defined place during dissociation of arena cues from room cues by rotation of the arena127
Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade127
Rates of change in quantitative traits from fixation of new mutations.127
Small molecule ISRIB suppresses the integrated stress response within a defined window of activation127
Short-interval severe fire erodes the resilience of subalpine lodgepole pine forests127
Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam.127
Orthorhombic crystals and three-dimensional structure of the potent toxin II from the scorpion Androctonus australis Hector.127
Trapping cDNAs encoding secreted proteins from the salivary glands of the malaria vector Anopheles gambiae127
Carbon under extreme conditions: Phase boundaries and electronic properties from first-principles theory127
Complex formation between methionine and a heme peptide from cytochrome c.127
Molecular asymmetry in extraterrestrial chemistry: Insights from a pristine meteorite127
Self-affirmation alters the brain’s response to health messages and subsequent behavior change127
Regulation of nuclear architecture, mechanics, and nucleocytoplasmic shuttling of epigenetic factors by cell geometric constraints127
A nod factor binding lectin with apyrase activity from legume roots127
Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis127
Molecular-dynamics simulations of urea nucleation from aqueous solution126
The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: Analysis of ESTs from the hermaphroditic strain126
Evolution of nematode-trapping cells of predatory fungi of the Orbiliaceae based on evidence from rRNA-encoding DNA and multiprotein sequences126
Evidence that an iron-nickel-carbon complex is formed by reaction of CO with the CO dehydrogenase from Clostridium thermoaceticum.126
Generation of varicella-zoster virus (VZV) and viral mutants from cosmid DNAs: VZV thymidylate synthetase is not essential for replication in vitro.126
Arabinogalactan-proteins from Nicotiana alata and Pyrus communis contain glycosylphosphatidylinositol membrane anchors126
Isolation and characterization of cDNA clones encoding a functional p34cdc2 homologue from Zea mays.126
Predicting errors from reconfiguration patterns in human brain networks126
Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice126
Jointly reduced inhibition and excitation underlies circuit-wide changes in cortical processing in Rett syndrome126
Population genetic implications from sequence variation in four Y chromosome genes126
Assembly of Weibel–Palade body-like tubules from N-terminal domains of von Willebrand factor126
Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport.126
Differential long-term and multilineage engraftment potential from subfractions of human CD34+cord blood cells transplanted into NOD/SCID mice126
Cyclodextrin-covered organic nanotubes derived from self-assembly of dendrons and their supramolecular transformation126
Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis.126
Exceptional transmission of plastids and mitochondria from the transplastomic pollen parent and its impact on transgene containment126
Modeling first impressions from highly variable facial images126
Models of earth structure inferred from neodymium and strontium isotopic abundances126
Distinguishing human ethnic groups by means of sequences from Helicobacter pylori : Lessons from Ladakh126
A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing126
Proteinase-activated receptor 2 (PAR 2 )-activating peptides: Identification of a receptor distinct from PAR 2 that regulates inte126
Nep1-like proteins from three kingdoms of life act as a microbe-associated molecular pattern in Arabidopsis126
Two RNA polymerase complexes from vesicular stomatitis virus-infected cells that carry out transcription and replication of genome RNA126
Electron injection into organic semiconductor devices from high work function cathodes126
Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.126
Cytologically normal cells from neoplastic cervical samples display extensive structural abnormalities on IR spectroscopy: Implications for tumor biology126
The pair of bacteriophytochromes from Agrobacterium tumefaciens are histidine kinases with opposing photobiological properties126
Haemophilus influenzae bacteremia and meningitis resulting from survival of a single organism126
Immobilized lipid in acetylcholine receptor-rich membranes from Torpedo marmorata.126
Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes to ferns126
YAP/TAZ-CDC42 signaling regulates vascular tip cell migration126
Neutralizing antibody titers against dengue virus correlate with protection from symptomatic infection in a longitudinal cohort126
Deciphering the genetic determinants for aerobic nicotinic acid degradation: The nic cluster from Pseudomonas putida KT2440125
Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets.125
Reconstitution of stretch-activated cation channels by expression of the α-subunit of the epithelial sodium channel cloned from osteoblasts125
Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes.125
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane125
Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450 BioI ACP complex125
Two-dimensional infrared spectra of isotopically diluted amyloid fibrils from Aβ40125
Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow125
Loss of function of a rice TPR-domain RNA-binding protein confers broad-spectrum disease resistance125
Free energy profiles from single-molecule pulling experiments125
Naturally acquired Duffy-binding protein-specific binding inhibitory antibodies confer protection from blood-stage Plasmodium vivax infection125
Trapping and spectroscopic characterization of an Fe III -superoxo intermediate from a nonheme mononuclear iron-containing enzyme125
Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily.125
Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them.125
Molecular cloning of the gene for the allatostatin family of neuropeptides from the cockroach Diploptera punctata.125
How enzymes can capture and transmit free energy from an oscillating electric field.125
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut125
Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA125
Cytoplasmic microtubules in tissue culture cells appear to grow from an organizing structure towards the plasma membrane.125
Epigenetic switch from repressive to permissive chromatin in response to cold stress125
Rapid equilibrium sampling initiated from nonequilibrium data125
Three members of a novel small gene-family from Arabidopsis thaliana able to complement functionally an Escherichia coli mutant defective 125
Postcranial morphology of the middle Pleistocene humans from Sima de los Huesos, Spain125
Evolution in biosynthetic pathways: two enzymes catalyzing consecutive steps in methionine biosynthesis originate from a common ancestor and possess a similar regulatory region.125
Cloning of a polycistronic cDNA from tomato encoding γ-glutamyl kinase and γ-glutamyl phosphate reductase125
Protein-electroblotting and -microsequencing strategies in generating protein data bases from two-dimensional gels.125
Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection125
Ash from the Toba supereruption in Lake Malawi shows no volcanic winter in East Africa at 75 ka125
Some transformations of color information from lateral geniculate nucleus to striate cortex125
Inhibitor κB-like proteins from a polydnavirus inhibit NF-κB activation and suppress the insect immune response125
The origin of modern metabolic networks inferred from phylogenomic analysis of protein architecture125
Nucleotide sequence of an RNA polymerase binding site from the DNA of bacteriophage fd.125
Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS125
Strong reproductive isolation between humans and Neanderthals inferred from observed patterns of introgression125
Directed evolution of an ultrastable carbonic anhydrase for highly efficient carbon capture from flue gas125
A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis125
Glucose Transfer from Dolichol Monophosphate Glucose: The Product Formed with Endogenous Microsomal Acceptor124
Role of ABC transporters in secretion of cholesterol from liver into bile124
An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.124
Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers124
chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and ty124
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues124
NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron–sulfur cluster N2 to quinone124
Differentiation of Lens Tissue from the Progeny of Chick Retinal Pigment Cells Cultured In Vitro : A Demonstration of a Switch of Cell Types in Clonal Cell Culture124
Dissection of Semliki Forest virus glycoprotein delivery from the trans-Golgi network to the cell surface in permeabilized BHK cells.124
Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain.124
Target cell-specific modulation of transmitter release at terminals from a single axon124
Frost halos from supercooled water droplets124
Electron Paramagnetic Resonance of Nitrogenase and Nitrogenase Components from Clostridium pasteurianum W5 and Azotobacter vinelandii OP124
Cross-national evidence of a negativity bias in psychophysiological reactions to news124
Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis.124
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution124
Ultraefficient thermophotovoltaic power conversion by band-edge spectral filtering124
TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter124
Endothelial plasmalemmal vesicles as elements in a system of branching invaginations from the cell surface.124
Harvesting renewable energy from Earth’s mid-infrared emissions124
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy124
Lightweight, flaw-tolerant, and ultrastrong nanoarchitected carbon124
Purified particulate methane monooxygenase from Methylococcus capsulatus (Bath) is a dimer with both mononuclear copper and a copper-containing cluster124
Evidence for sharp increase in the economic damages of extreme natural disasters124
Unleashing floret fertility in wheat through the mutation of a homeobox gene124
Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries.124
Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta.124
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2.124
Primary structure of the M subunit of the reaction center from Rhodopseudomonas sphaeroides123
Complete in vitro generation of fertile oocytes from mouse primordial germ cells123
A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells123
A model of the molten globule state from molecular dynamics simulations.123
Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion123
Contrasting climate change impact on river flows from high-altitude catchments in the Himalayan and Andes Mountains123
Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities123
Human RORγt + T H 17 cells preferentially differentiate from naive FOXP3 + Treg in the presence123
Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA fromTaxusand functional expression inEscherichia coli123
Phenotypic differences between Salmonella and Escherichia coli resulting from the disparate regulation of homologous genes123
Protein folding pathways from replica exchange simulations and a kinetic network model123
Archaeological evidence of teosinte domestication from Guilá Naquitz, Oaxaca123
LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells123
Structural analysis at 2.2 Å of orthorhombic crystals presents the asymmetry of the allophycocyanin–linker complex, AP⋅L C 7.8 , from phycobil123
Lessons from border cell migration in the Drosophila ovary: A role for myosin VI in dissemination of human ovarian cancer123
SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage123
Circadian clock-controlled genes isolated from Neurospora crassa are late night- to early morning-specific123
Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver.123
Mosquito feeding behavior and how it influences residual malaria transmission across Africa123
Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity123
Hurricane Sandy’s flood frequency increasing from year 1800 to 2100123
Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury123
α-Synuclein structures from fluorescence energy-transfer kinetics: Implications for the role of the protein in Parkinson's disease123
Reversal of developmental restrictions in neural crest lineages: Transition from Schwann cells to glial-melanocytic precursors in vitro122
Heparin- and sulfatide-binding peptides from the type I repeats of human thrombospondin promote melanoma cell adhesion.122
Phytoplankton species richness scales consistently from laboratory microcosms to the world's oceans122
Evidence for multiple adaptive peaks from populations of bacteria evolving in a structured habitat.122
Laminin and fibronectin in cell adhesion: enhanced adhesion of cells from regenerating liver to laminin.122
Reconstitution of D-glucose transport catalyzed by a protein fraction from human erythrocytes in sonicated liposomes.122
Community ecology in a changing environment: Perspectives from the Quaternary122
Core formation and core composition from coupled geochemical and geophysical constraints122
Anopheles gambiae pilot gene discovery project: Identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines122
Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma122
Hepatitis C virus variants from Vietnam are classifiable into the seventh, eighth, and ninth major genetic groups.122
Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian,Halocynthia roretzi122
Model for anaphase B: Role of three mitotic motors in a switch from poleward flux to spindle elongation122
Calcium release from the endoplasmic reticulum of higher plants elicited by the NADP metabolite nicotinic acid adenine dinucleotide phosphate122
Reciprocal electromechanical properties of rat prestin: The motor molecule from rat outer hair cells122
Intraprotein electron transfer between tyrosine and tryptophan in DNA photolyase from Anacystis nidulans122
The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus122
Protein interactions and ligand binding: From protein subfamilies to functional specificity122
Circular DNA tumor viruses make circular RNAs122
Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes122
Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space122
Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem122
Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.122
Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor.122
A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function122
AAV cis -regulatory sequences are correlated with ocular toxicity122
Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complex122
Covalently bound VirD2 protein of Agrobacterium tumefaciens protects the T-DNA from exonucleolytic degradation.122
Unsupervised learning of vowel categories from infant-directed speech122
Sex differences in adult lifespan and aging rates of mortality across wild mammals122
Mechanistic insights into c-di-GMP–dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa122
α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson’s disease122
Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung.122
COPI buds 60-nm lipid droplets from reconstituted water–phospholipid–triacylglyceride interfaces, suggesting a tension clamp function122
Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways122
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway121
Characterization of a calmodulin-binding transporter from the plasma membrane of barley aleurone121
Observation of spatial propagation of amyloid assembly from single nuclei121
Ionic factors in release of 45Ca2+ from chicken cerebral tissue by electromagnetic fields.121
Body temperatures of modern and extinct vertebrates from 13 C- 18 O bond abundances in bioapatite121
Fine-scale damage estimates of particulate matter air pollution reveal opportunities for location-specific mitigation of emissions121
From biosilicification to tailored materials: Optimizing hydrophobic domains and resistance to protonation of polyamines121
Differential expression of human tRNA genes drives the abundance of tRNA-derived fragments121
Photoregulation of a phytochrome gene promoter from oat transferred into rice by particle bombardment.121
Purification of an Ion-Stimulated Adenosine Triphosphatase from Plant Roots: Association with Plasma Membranes121
Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells121
Diffusion models of ion-channel gating and the origin of power-law distributions from single-channel recording.121
Decline in climate resilience of European wheat121
A nonspecific fatty acid within the bumblebee mating plug prevents females from remating121
The antioxidant protein alkylhydroperoxide reductase of Helicobacter pylori switches from a peroxide reductase to a molecular chaperone function121
Eocene habitat shift from saline to freshwater promoted Tethyan amphipod diversification121
Turning a protein kinase on or off from a single allosteric site via disulfide trapping121
Reductions in emissions from deforestation from Indonesia’s moratorium on new oil palm, timber, and logging concessions121
Philopatry of male marine turtles inferred from mitochondrial DNA markers121
Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy121
TRPA channels distinguish gravity sensing from hearing in Johnston's organ121
Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine121
Cell-cycle-specific cDNAs from mammalian cells temperature sensitive for growth.121
The debt of nations and the distribution of ecological impacts from human activities121
Neisseria meningitidisporin PorB interacts with mitochondria and protects cells from apoptosis121
From transforming growth factor-β signaling to androgen action: Identification of Smad3 as an androgen receptor coregulator in prostate cancer cells121
Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.121
Structure of the TDP- epi -vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway121
Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution121
X chromosome-linked and mitochondrial gene control of Leber hereditary optic neuropathy: evidence from segregation analysis for dependence on X chromosome inactivation.121
Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide.121
Sialokinin I and II: vasodilatory tachykinins from the yellow fever mosquito Aedes aegypti.120
Memory and resource tracking drive blue whale migrations120
An Endonuclease Activity from Escherichia coli Absent from Certain rec - Strains120
A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore120
Near doubling of Brazil’s intensive row crop area since 2000120
Diversity in prion protein oligomerization pathways results from domain expansion as revealed by hydrogen/deuterium exchange and disulfide linkage120
Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain120
In vitro properties of the first ORF protein from mouse LINE-1 support its role in ribonucleoprotein particle formation during retrotransposition120
Characterization of pHV2 from Halobacterium volcanii and its use in demonstrating transformation of an archaebacterium.120
Heterodimeric geranyl(geranyl)diphosphate synthase from hop ( Humulus lupulus ) and the evolution of monoterpene biosynthesis120
Electric power from offshore wind via synoptic-scale interconnection120
Multiple translational products from a five-nucleotide ribozyme120
Reduced transmission of human schistosomiasis after restoration of a native river prawn that preys on the snail intermediate host120
uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues120
Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1)120
Atmospheric escape from the TRAPPIST-1 planets and implications for habitability120
Short-term administration of omega 3 fatty acids from fish oil results in increased transthyretin transcription in old rat hippocampus120
Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α- O -benzoyltransferase cDNA from Taxus and functional expression in 120
Photogeneration of hydrogen from water using CdSe nanocrystals demonstrating the importance of surface exchange120
Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae.120
The structural basis for the transition from Ras-GTP to Ras-GDP120
Circadian clock protein Rev-erbα regulates neuroinflammation120
Using naturally occurring climate resilient corals to construct bleaching-resistant nurseries120
A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia120
Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers120
The γ-subunit rotation and torque generation in F 1 -ATPase from wild-type or uncoupled mutant Escherichia coli120
Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence.120
Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase.120
Magnetic self-assembly of three-dimensional surfaces from planar sheets120
Independent evolution of knuckle-walking in African apes shows that humans did not evolve from a knuckle-walking ancestor120
Cranial morphology of early Americans from Lagoa Santa, Brazil: Implications for the settlement of the New World120
A computationally directed screen identifying interacting coiled coils from Saccharomyces cerevisiae119
Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus119
Reaction to phytotoxins in a potato population derived from mesophyll protoplasts119
Extraction of mechanical properties of materials through deep learning from instrumented indentation119
Nitrilase in biosynthesis of the plant hormone indole-3-acetic acid from indole-3-acetonitrile: cloning of the Alcaligenes gene and site-directed mutagenesis of cysteine residues.119
Gene-regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2119
Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells119
Unexpected intracellular biodegradation and recrystallization of gold nanoparticles119
Evidence for adaptive radiation from a phylogenetic study of plant defenses119
Analysis of a carbapenem-hydrolyzing class A beta-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein.119
Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy119
Bovine cone photoreceptor cGMP phosphodiesterase structure deduced from a cDNA clone.119
Isolation of high-affinity GTP aptamers from partially structured RNA libraries119
Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA119
Hazard from Himalayan glacier lake outburst floods119
Trait-like variants in human functional brain networks119
A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo.119
Functional characterization of B lymphocytes generatedin vitrofrom embryonic stem cells119
The structural basis for biphasic kinetics in the folding of the WW domain from a formin-binding protein: Lessons for protein design?119
Energy and air pollution benefits of household fuel policies in northern China119
Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin119
Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.119
Role of nitric oxide in interleukin 2-induced corticotropin-releasing factor release from incubated hypothalami.119
Causal inference in coupled human and natural systems119
GreA protein: a transcription elongation factor from Escherichia coli.119
Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carri119
Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen119
Molybdopterin guanine dinucleotide: a modified form of molybdopterin identified in the molybdenum cofactor of dimethyl sulfoxide reductase from Rhodobacter sphaeroides forma specialis denitrificans.119
Microtubules from Mammalian Brain: Some Properties of Their Depolymerization Products and a Proposed Mechanism of Assembly and Disassembly119
A new hemoglobin gene from soybean: a role for hemoglobin in all plants.119
Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension119
An Andean origin of Phytophthora infestans inferred from mitochondrial and nuclear gene genealogies119
Prebiotic synthesis from CO atmospheres: Implications for the origins of life119
Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection118
Toxicity drives facilitation between 4 bacterial species118
A new Late Miocene great ape from Kenya and its implications for the origins of African great apes and humans118
Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor specie118
Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells.118
Lysyl-Protocollagen Hydroxylase Deficiency in Fibroblasts from Siblings with Hydroxylysine-Deficient Collagen118
Interferon: purification and initial characterization from human diploid cells.118
PRELIMINARY ANALYSIS OF THE REQUIREMENTS FOR FUSION FROM WITHIN AND FUSION FROM WITHOUT BY NEWCASTLE DISEASE VIRUS118
Nuclear and mitochondrial DNA sequences from two Denisovan individuals118
Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R118
Anti-epidermal-cell-surface pemphigus antibody detaches viable epidermal cells from culture plates by activation of proteinase.118
Sanfilippo Syndrome: Profound Deficiency of Alpha-Acetylglucosaminidase Activity in Organs and Skin Fibroblasts from Type-B Patients118
On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles118
The global mass and average rate of rubisco118
Heptameric (L12) 6 /L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria118
Changes in belowground biodiversity during ecosystem development118
ISOLATION OF ADENOSINE AMINO ACID ESTERS FROM A RIBONUCLEASE DIGEST OF SOLUBLE, LIVER RIBONUCLEIC ACID118
A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast.117
Bacteria capture iron from heme by keeping tetrapyrrol skeleton intact117
THE TWO JUVENILE HORMONES FROM THE CECROPIA SILK MOTH117
Characterization of a histone-like protein extracted from yeast mitochondria.117
Indoles from commensal bacteria extend healthspan117
Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro.117
Self-assembly of large, ordered lamellae from non-bilayer lipids and integral membrane proteinsin vitro117
Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure117
Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency117
Linkage of mating-type loci distinguishes bipolar from tetrapolar mating in basidiomycetous smut fungi.117
Early evolution of photosynthesis: clues from nitrogenase and chlorophyll iron proteins.117
Disentangling the abundance–impact relationship for invasive species117
Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy117
Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation117
Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways.117
Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde117
Isolation and characterization of a tobacco mosaic virus-inducible myb oncogene homolog from tobacco117
Production of zebrafish germ-line chimeras from embryo cell cultures117
Early modern humans from the Peştera Muierii, Baia de Fier, Romania117
Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model117
A "public" T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotype117
Genomic and cranial phenotype data support multiple modern human dispersals from Africa and a southern route into Asia117
Maximizing gene expression from plasmid vectors containing the lambda PL promoter: strategies for overproducing transcription termination factor rho.117
Role of vascular normalization in benefit from metronomic chemotherapy116
Inhibitors of DNA topoisomerase II prevent chromatid separation in mammalian cells but do not prevent exit from mitosis.116
Programmed cell death in castor bean endosperm is associated with the accumulation and release of a cysteine endopeptidase from ricinosomes116
A gating mechanism proposed from a simulation of a human α7 nicotinic acetylcholine receptor116
RECONSTITUTION OF COMPLETE ORGANS FROM SINGLE-CELL SUSPENSIONS OF CHICK EMBRYOS IN ADVANCED STAGES OF DIFFERENTIATION116
Evolution of treatment effects over time: Empirical insight from recursive cumulative metaanalyses116
GenBank is a reliable resource for 21st century biodiversity research116
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin116
Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation116
Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex.116
Chromosomal replication origin from the marine bacterium Vibrio harveyi functions in Escherichia coli: oriC consensus sequence.116
Single-molecule enzymology of RNA: Essential functional groups impact catalysis from a distance116
Integrating phase and composition of secondary organic aerosol from the ozonolysis of α-pinene116
The neural development and organization of letter recognition: Evidence from functional neuroimaging, computational modeling, and behavioral studies116
Calcium-Dependent Norepinephrine Release from Presynaptic Nerve Endings In Vitro116
Calculation of immigration and extinction curves from the species-area-distance relation116
A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years116
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody116
Ultrafast photodriven intramolecular electron transfer from an iridium-based water-oxidation catalyst to perylene diimide derivatives116
Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo.116
Avicins, a family of triterpenoid saponins fromAcacia victoriae(Bentham), inhibit activation of nuclear factor-κB by inhibiting both its nuclear localization and ability to bind DNA116
Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease.116
Characterization and mapping of RNase T1-resistant oligonucleotides derived from the genomes of Akv and MCF murine leukemia viruses.116
Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease.116
Secretion of functional antibody and Fab fragment from yeast cells.116
Dissociation from albumin: a potentially rate-limiting step in the clearance of substances by the liver.116
Human origins and the transition from promiscuity to pair-bonding116
Mobile platform for rapid sub–picogram-per-milliliter, multiplexed, digital droplet detection of proteins116
Elevated levels of diesel range organic compounds in groundwater near Marcellus gas operations are derived from surface activities116
Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster.116
The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis116
A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus115
Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others115
Structure, function, and phylogeny of [Arg8]vasotocinreceptors from teleost fish and toad.115
Mendel’s dwarfing gene: cDNAs from the Le alleles and function of the expressed proteins115
New view of lipid bilayer dynamics from 2H and 13C NMR relaxation time measurements.115
MicroRNA-like viral small RNA from Dengue virus 2 autoregulates its replication in mosquito cells115
An rbcL sequence from a Miocene Taxodium (bald cypress).115
The role of forest conversion, degradation, and disturbance in the carbon dynamics of Amazon indigenous territories and protected areas115
Simultaneous cryo X-ray ptychographic and fluorescence microscopy of green algae115
Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells115
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy115
Nitric oxide induces CD4+CD25+Foxp3regulatory T cells from CD4+CD25T cells via p53, IL-2, and OX40115
Adaptive growth factor delivery from a polyelectrolyte coating promotes synergistic bone tissue repair and reconstruction115
Mammalian mitochondria have the innate ability to import tRNAs by a mechanism distinct from protein import115
Experimental results from a preclinical X-ray phase-contrast CT scanner115
Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients115
Pseudomonas aeruginosaregulates flagellin expression as part of a global response to airway fluid from cystic fibrosis patients115
Segregating the significant from the mundane on a moment-to-moment basis via direct and indirect amygdala contributions115
Highly stable expression of a foreign gene from rabies virus vectors.115
Virtual groundwater transfers from overexploited aquifers in the United States115
A DETECTION METHOD AND PROBABILISTIC MODELS FOR ASSESSING INFORMATION PROCESSING FROM BRIEF VISUAL DISPLAYS115
Synthesis of liquid fuel via direct hydrogenation of CO 2115
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway115
Modification of excitation and charge transfer in cavity quantum-electrodynamical chemistry115
Cloning and sequence analysis of cDNA species coding for the two subunits of inhibin from bovine follicular fluid.115
Construction of the mycoplasma evolutionary tree from 5S rRNA sequence data.115
Selective growth in serum-free hormone-supplemented medium of tumor cells obtained by biopsy from patients with small cell carcinoma of the lung.115
Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist115
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)115
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes115
CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations115
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia.115
mShal, a subfamily of A-type K+ channel cloned from mammalian brain.115
Glass rheology: From mode-coupling theory to a dynamical yield criterion115
Molecular cloning of violaxanthin de-epoxidase from romaine lettuce and expression in Escherichia coli.115
DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1115
Childhood trauma history is linked to abnormal brain connectivity in major depression115
Recurrent symbiont recruitment from fungal parasites in cicadas115
Redox and pH gradients drive amino acid synthesis in iron oxyhydroxide mineral systems115
The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization115
Comparison of circumsporozoite proteins from avian and mammalian malarias: biological and phylogenetic implications.115
Purification of a factor that restores translation of vesicular stomatitis virus mRNA in extracts from poliovirus-infected HeLa cells.115
Inferring interaction partners from protein sequences115
Isolation and characterization of lymphocyte-like cells from a lamprey114
Dystrophin is transcribed in brain from a distant upstream promoter.114
Cloning, sequence, and expression of the lysostaphin gene from Staphylococcus simulans.114
Protection of retroviral DNA from autointegration: involvement of a cellular factor.114
Alfalfa benefits fromMedicago truncatula: TheRCT1gene fromM. truncatulaconfers broad-spectrum resistance to anthracnose in alfalfa114
Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance114
Sensitivity to vanadate and isoforms of subunits A and B distinguish the osteoclast proton pump from other vacuolar H+ ATPases.114
Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver: evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia.114
Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary muscle preparations from guinea pig heart by analogs of amiloride.114
Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli.114
Molecular cloning of infectious integrated murine leukemia virus DNA from infected mouse cells.114
Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis114
A-type potassium channels expressed from Shaker locus cDNA.114
Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney.114
Escape from strange repellers114
The functional importance of human foot muscles for bipedal locomotion114
Anomalous diffusion, spatial coherence, and viscoelasticity from the energy landscape of human chromosomes114
Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.114
Free methionine-( R )-sulfoxide reductase from Escherichia coli reveals a new GAF domain function114
Femtosecond spontaneous-emission studies of reaction centers from photosynthetic bacteria.114
DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells.114
Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons114
Adrenergic regulation of intercellular communications between cultured striatal astrocytes from the mouse.114
An alternative pathway for signal flow from rod photoreceptors to ganglion cells in mammalian retina.114
Infection by the parasitic helminth Trichinella spiralis activates a Tas2r-mediated signaling pathway in intestinal tuft cells114
Eocene greenhouse climate revealed by coupled clumped isotope-Mg/Ca thermometry114
Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates114
Engraftment of a clonal bone marrow stromal cell line in vivo stimulates hematopoietic recovery from total body irradiation.114
Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death.114
Magnetotactic bacteria form magnetite from a phosphate-rich ferric hydroxide via nanometric ferric (oxyhydr)oxide intermediates114
Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus.114
Principles of self-assembly of helical pores from dendritic dipeptides114
VipD is a Rab5-activated phospholipase A 1 that protects Legionella pneumophila from endosomal fusion113
Properties of a toxin from the sea anemone Stoichacis helianthus, including specific binding to sphingomyelin.113
Maculosin, a host-specific phytotoxin for spotted knapweed from Alternaria alternata113
Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination113
Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive113
Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.113
Cloned avirulence genes from the tomato pathogen Pseudomonas syringae pv. tomato confer cultivar specificity on soybean113
Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration.113
Small-scale urban agriculture results in high yields but requires judicious management of inputs to achieve sustainability113
In vitro activation of human herpesviruses 6 and 7 from latency.113
A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens113
Proton exit from the heme–copper oxidase of Escherichia coli113
Estimating the proportion of bystander selection for antibiotic resistance among potentially pathogenic bacterial flora113
The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored byin vitrophotorepair of cyclobutane pyrimidine dimers113
Involvement of transforming growth factor alpha in the release of luteinizing hormone-releasing hormone from the developing female hypothalamus.113
STIMULATION OF C 14 -MELATONIN SYNTHESIS FROM C 14 -TRYPTOPHAN BY NORADRENALINE IN RAT PINEAL IN ORGAN CULTURE113
Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.113
Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes113
Crystal structure of a DEAD box protein from the hyperthermophile Methanococcus jannaschii113
EVIDENCE FOR “GIBBERELLIN-LIKE” SUBSTANCES FROM FLOWERING PLANTS113
Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression.113
From Bloch oscillations to many-body localization in clean interacting systems113
Humanized mouse model supports development, function, and tissue residency of human natural killer cells113
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals113
Transfer of resistance traits from carrot into tobacco by asymmetric somatic hybridization: Regeneration of fertile plants113
Papain-Solubilized HL-A Antigens from Cultured Human Lymphocytes Contain Two Peptide Fragments112
Successive passaging of a plant-associated microbiome reveals robust habitat and host genotype-dependent selection112
Standing genetic variation as the predominant source for adaptation of a songbird112
Alterations in the phenotype of plant cells studied by NH 2 -terminal amino acid-sequence analysis of proteins electroblotted from two-dimensional gel-separated tota112
Ferritin: isolation of aluminum-ferritin complex from brain.112
Isolation and structure of pro-somatostatin: a putative somatostatin precursor from pig hypothalamus.112
Widespread soil bacterium that oxidizes atmospheric methane112
Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone112
Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes112
Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae , induces apoptosis in some human cell lines112
Reconstruction of protein networks from an atlas of maize seed proteotypes112
Basal and adenosine receptor-stimulated levels of cAMP are reduced in lymphocytes from alcoholic patients.112
Blood-borne seeding by hematopoietic and endothelial precursors from the allantois112
Conserved fungal effector suppresses PAMP-triggered immunity by targeting plant immune kinases112
A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells112
Mapping of human chromosomal regions related to neoplasia: Evidence from chromosomes 1 and 17112
The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination112
Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions112
Patterns of prehistoric human mobility in Polynesia indicated by mtDNA from the Pacific rat112
Racial disparities in school-based disciplinary actions are associated with county-level rates of racial bias112
PCR analysis of DNA from 70-year-old sections of rodless retina demonstrates identity with the mouse rd defect.112
Sequences from a prokaryotic genome or the mouse dihydrofolate reductase gene can restore the import of a truncated precursor protein into yeast mitochondria.112
Characterization of a membrane-associated receptor from bovine liver that binds phosphomannosyl residues of bovine testicular beta-galactosidase.112
Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures112
Guanine riboswitch variants from Mesoplasma florum selectively recognize 2′-deoxyguanosine112
MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs112
Hydration repulsion between biomembranes results from an interplay of dehydration and depolarization112
Tumor-associated fibroblasts predominantly come from local and not circulating precursors112
Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome112
Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity.112
Extraterrestrial ribose and other sugars in primitive meteorites112
Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin112
Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop112
Socioeconomic gradients in child development in very young children: Evidence from India, Indonesia, Peru, and Senegal112
Proteinase inhibitor-inducing factor activity in tomato leaves resides in oligosaccharides enzymically released from cell walls112
Modification of the 5'-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus.112
A tensor higher-order singular value decomposition for integrative analysis of DNA microarray data from different studies111
Differentiation of Lens-Like Structures from Newt Iris Epithelial Cells In Vitro111
Evolutionary history of Polyneoptera and its implications for our understanding of early winged insects111
Heat stress directly impairs gut integrity and recruits distinct immune cell populations into the bovine intestine111
De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific111
Evolution of the plankton paleome in the Black Sea from the Deglacial to Anthropocene111
Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1β secretion111
Macrophage activation: priming activity from a T-cell hybridoma is attributable to interferon-gamma.111
Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas.111
Poxviruses as possible vectors for horizontal transfer of retroposons from reptiles to mammals111
Comparison of syncytiotrophoblast generated from human embryonic stem cells and from term placentas111
High blood pressure arising from a defect in vascular function111
Measuring tubulin content in Toxoplasma gondii : A comparison of laser-scanning confocal and wide-field fluorescence microscopy111
Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.111
Predicting the size of the T-cell receptor and antibody combining region from consideration of efficient self-nonself discrimination.111
scMerge leverages factor analysis, stable expression, and pseudoreplication to merge multiple single-cell RNA-seq datasets111
Realizing the values of natural capital for inclusive, sustainable development: Informing China’s new ecological development strategy111
Defining the core essential genome of Pseudomonas aeruginosa111
Enterococcus faecalis from newborn babies regulate endogenous PPARγ activity and IL-10 levels in colonic epithelial cells111
Tracing the ingredients for a habitable earth from interstellar space through planet formation111
Interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression.111
Norepinephrine, vasopressin, glucagon, and A23187 induce efflux of calcium from an exchangeable pool in isolated rat hepatocytes110
Isolation and localization of DNA segments from specific human chromosomes110
Formation of a Vaccinia Virus Structural Polypeptide from a Higher Molecular Weight Precursor: Inhibition by Rifampicin110
Generation of functional eggs and sperm from cryopreserved whole testes110
SULFOLIPID FROM VIRULENT TUBERCLE BACILLI110
Organic enantiomeric high- T c ferroelectrics110
Features of the Arabidopsis recombination landscape resulting from the combined loss of sequence variation and DNA methylation110
Leading a meaningful life at older ages and its relationship with social engagement, prosperity, health, biology, and time use110
Structure of the dimeric ATP synthase from bovine mitochondria110
Generation of reactive oxygen species by lethal attacks from competing microbes110
Delineation of putative mechanisms involved in antibody-mediated clearance of rabies virus from the central nervous system.110
Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex110
Mantle wedge infiltrated with saline fluids from dehydration and decarbonation of subducting slab110
Discontinuous epitopes of hepatitis B surface antigen derived from a filamentous phage peptide library.110
A photostable fluorescent marker for the superresolution live imaging of the dynamic structure of the mitochondrial cristae110
Pacific bluefin tuna transport Fukushima-derived radionuclides from Japan to California110
Long-term music training tunes how the brain temporally binds signals from multiple senses110
Physicochemical Characterization of Mitochondrial DNA from Pea Leaves110
Approaching infinite affinity through engineering of peptide–protein interaction110
Protein kinase involved in lung injury susceptibility: Evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment110
New neural activity patterns emerge with long-term learning110
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice110
Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity110
Target-induced formation of neuraminidase inhibitors from in vitro virtual combinatorial libraries110
Fossilized high pressure from the Earth's deep interior: The coesite-in-diamond barometer110
Lessons about parks and poverty from a decade of forest loss and economic growth around Kibale National Park, Uganda110
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates110
Roll up nanowire battery from silicon chips110
A new Eocene archaeocete (Mammalia, Cetacea) from India and the time of origin of whales110
A Factor from a Transformed Cell Line That Affects Cell Migration110
The heme groups of cytochrome o from Escherichia coli.110
Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer110
Deep learning enables high-quality and high-throughput prediction of enzyme commission numbers110
Indirect nitrous oxide emissions from streams within the US Corn Belt scale with stream order110
Preformed chromatin topology assists transcriptional robustness of Shh during limb development110
Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli.110
Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation110
Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis.110
EARLY BUD-BREAK 1 ( EBB1 ) is a regulator of release from seasonal dormancy in poplar trees110
Isolation of a cytokinin gene, ZOG1 , encoding zeatin O -glucosyltransferase from Phaseolus lunatus109
Generation of osteoclast-inductive and osteoclastogenic cell lines from the H-2KbtsA58 transgenic mouse.109
Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs109
Male fitness increases when females are eliminated from gene pool: Implications for the Y chromosome109
Low-cost high-efficiency system for solar-driven conversion of CO 2 to hydrocarbons109
MYB36 regulates the transition from proliferation to differentiation in the Arabidopsis root109
Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 Å resolution109
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1109
Conserved biological function between Pax- 2 and Pax- 5 in midbrain and cerebellum development: Evidence from targeted mutations109
Sustained stimulation shifts the mechanism of endocytosis from dynamin-1-dependent rapid endocytosis to clathrin- and dynamin-2-mediated slow endocytosis in chromaffin cells109
O2-sensitive K+ currents in carotid body chemoreceptor cells from normoxic and chronically hypoxic rats and their roles in hypoxic chemotransduction.109
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers109
Amplification of nitric oxide signaling by interstitial cells isolated from canine colon.109
Importin/karyopherin protein family members required for mRNA export from the nucleus109
Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis109
Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence109
Gene transfers from diverse bacteria compensate for reductive genome evolution in the chromatophore of Paulinella chromatophora109
A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells.109
Dendritic cells acquire the MAGE-3 human tumor antigen from apoptotic cells and induce a class I-restricted T cell response109
CIS display: In vitro selection of peptides from libraries of protein–DNA complexes109
Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1109
Isolation and Properties of a Macromolecular, Water-Soluble, Immuno-Adjuvant Fraction from the Cell Wall of Mycobacterium smegmatis109
The survival of brain transplants is enhanced by extracts from injured brain.109
Secretion from chromaffin cells is controlled by chromogranin A-derived peptides.109
Binding properties of a cell adhesion molecule from neural tissue.109
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA109
FLIP switches Fas-mediated glucose signaling in human pancreatic β cells from apoptosis to cell replication109
Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.109
Self-assembly of crystalline nanotubes from monodisperse amphiphilic diblock copolypeptoid tiles109
Protein solution structure determination using distances from two-dimensional nuclear Overhauser effect experiments: effect of approximations on the accuracy of derived structures.109
T lineage differentiation from human embryonic stem cells108
Specific binding of a fungal glucan phytoalexin elicitor to membrane fractions from soybean Glycine max108
SLC4 family transporters in a marine diatom directly pump bicarbonate from seawater108
Molecular dynamics simulations of protein folding from the transition state108
Nascent ribosomes from HeLa cells.108
ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors108
Invasive grasses increase fire occurrence and frequency across US ecoregions108
The CD5 ectodomain interacts with conserved fungal cell wall components and protects from zymosan-induced septic shock-like syndrome108
Increased nitrous oxide emissions from Arctic peatlands after permafrost thaw108
Distribution of Saccharide Residues on Membrane Fragments from a Myeloma-Cell Homogenate: Its Implications for Membrane Biogenesis108
Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues.108
The distance that kinesin-1 holds its cargo from the microtubule surface measured by fluorescence interference contrast microscopy108
Dale's hypothesis revisited: different neuropeptides derived from a common prohormone are targeted to different processes.108
Molecular evolution of the myosin family: relationships derived from comparisons of amino acid sequences.108
Phenotypic integration emerges from aposematism and scale in poison frogs108
Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes108
Noninvasive preimplantation genetic testing for aneuploidy in spent medium may be more reliable than trophectoderm biopsy108
PCR analysis of tissue samples from the 1979 Sverdlovsk anthrax victims: The presence of multiple Bacillus anthracis strains in different victims108
Monoclonal antibodies to the thyrotropin receptor: stimulating and blocking antibodies derived from the lymphocytes of patients with Graves disease.108
Structural and functional alterations of a colicin-resistant mutant of OmpF porin from Escherichia coli.108
Dark-light: model for nightblindness from the human rhodopsin Gly-90-->Asp mutation.108
Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix108
Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells.108
TLR4-mediated expulsion of bacteria from infected bladder epithelial cells108
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection108
Biological composition and microbial dynamics of sinking particulate organic matter at abyssal depths in the oligotrophic open ocean108
Auxin-Induced Hydrogen Ion Excretion from Avena Coleoptiles108
Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology108
Predicting personality from patterns of behavior collected with smartphones108
Pph3–Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage108
In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release108
Interrelationship between poly (ADP-Rib) synthesis, intracellular NAD levels, and muscle or cartilage differentiation from mesodermal cells of embryonic chick limb.108
Protein kinase CK2 modulates developmental functions of the abscisic acid responsive protein Rab17 from maize108
Switch from intracellular to intercellular invasion during water stress-tolerant legume nodulation107
Item memory, source memory, and the medial temporal lobe: Concordant findings from fMRI and memory-impaired patients107
IN VITRO AND IN VIVO EFFECTS OF A NERVE GROWTH-STIMULATING AGENT ISOLATED FROM SNAKE VENOM107
Functional connectomics of affective and psychotic pathology107
Age-related inflammation triggers skeletal stem/progenitor cell dysfunction107
Energetic regulation of coordinated leader–follower dynamics during collective invasion of breast cancer cells107
Batrachotoxin alkaloids from passerine birds: A second toxic bird genus ( Ifrita kowaldi ) from New Guinea107
LFG : An anti-apoptotic gene that provides protection from Fas-mediated cell death107
CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis107
Genetically encodable bioluminescent system from fungi107
Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering107
Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor107
Recovery from anti-VIII:C (antihemophilic factor) autoimmune disease is dependent on generation of antiidiotypes against anti-VIII:C autoantibodies.107
Attenuation and processing of RNA from the rplJL--rpoBC transcription unit of Escherichia coli.107
Temporally and spectrally resolved subpicosecond energy transfer within the peripheral antenna complex (LH2) and from LH2 to the core antenna complex in photosynthetic purple bacteria.107
Isolation of a 5-kilodalton actin-sequestering peptide from human blood platelets.107
A relaxin-like peptide purified from radial nerves induces oocyte maturation and ovulation in the starfish, Asterina pectinifera107
Localization of Methylated Arginine in the A1 Protein from Myelin107
Sex-chromosome dosage effects on gene expression in humans107
CD11b + Ly6G myeloid cells mediate mechanical inflammatory pain hypersensitivity107
The Fenton oxidation mechanism: reactivities of biologically relevant substrates with two oxidizing intermediates differ from those predicted for the hydroxyl radical.107
Cellular calcium fluctuations in mammalian heart: direct evidence from noise analysis of aequorin signals in Purkinje fibers.107
Arthropods in amber from the Triassic Period107
The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii107
Oreopithecus was a bipedal ape after all: Evidence from the iliac cancellous architecture107
Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver107
From oligonucleotide shapes to genomic SELEX: Novel biological regulatory loops107
Magnesium-aspartate-based crystallization switch inspired from shell molt of crustacean107
Analysis of protein solvent interactions in glucose dehydrogenase from the extreme halophile Haloferax mediterranei107
Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites.107
Protein preservation and DNA retrieval from ancient tissues107
Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities107
Epistasis between antibiotic tolerance, persistence, and resistance mutations107
Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.107
Epidermal growth factor and expression of specific genes: effects on cultured rat pituitary cells are dissociable from the mitogenic response.107
Carbohydrate structure and cell differentitation: unique properties of fucosyl-glycopeptides isolated from embryonal carcinoma cells.107
Dramatic increase in naïve T cell turnover is linked to loss of naïve T cells from old primates107
Membranes and phospholipids of liver mitochondria from chronic alcoholic rats are resistant to membrane disordering by alcohol.107
Growth rate of crystalline ice and the diffusivity of supercooled water from 126 to 262 K106
Uncoupling of sustained MAMP receptor signaling from early outputs in an Arabidopsis endoplasmic reticulum glucosidase II allele106
Universality and flexibility in gene expression from bacteria to human106
Three-dimensional, Bayesian image reconstruction from sparse and noisy data sets: Near-infrared fluorescence tomography106
Genes regulating the plant cell cycle: isolation of a mitotic-like cyclin from Arabidopsis thaliana.106
New World cattle show ancestry from multiple independent domestication events106
Global change effects on plant communities are magnified by time and the number of global change factors imposed106
Apolipoprotein B variant derived from rat intestine.106
Insights from past millennia into climatic impacts on human health and survival106
CD8+T cells recognize an inclusion membrane-associated protein from the vacuolar pathogenChlamydia trachomatis106
Functionally conserved architecture of hepatitis C virus RNA genomes106
Snapshot of a key intermediate in enzymatic thiamin catalysis: Crystal structure of the α-carbanion of (α,β-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from 106
Functional expression of a Δ12 fatty acid desaturase gene from spinach in transgenic pigs106
From patterns to processes: Phase and density dependencies in the Canadian lynx cycle106
Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain106
Myosin-actin interaction plays an important role in human immunodeficiency virus type 1 release from host cells.106
Properties of a copper-containing cytochrome ba3: a second terminal oxidase from the extreme thermophile Thermus thermophilus.106
Adaptive evolution in the Arabidopsis MADS-box gene family inferred from its complete resolved phylogeny106
Crystal structure of LeuA from Mycobacterium tuberculosis , a key enzyme in leucine biosynthesis106
Quantum speciation in Aegilops : Molecular cytogenetic evidence from rDNA cluster variability in natural populations106
Stochastic inhibitor release and binding from single-enzyme molecules106
Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases106
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis106
Defects in embryonic hindbrain development and fetal resorption resulting from vitamin A deficiency in the rat are prevented by feeding pharmacological levels of all- trans- 106
Efficient removal of uracil from G.U mispairs by themismatch-specific thymine DNA glycosylase from HeLa cells.106
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans106
Isolation from the asian mouse Mus caroli of an endogenous type C virus related to infectious primate type C viruses.106
Combinatorial interaction network of abscisic acid receptors and coreceptors from Arabidopsis thaliana106
Isolation of complementary DNA clones encoding pathogenesis-related proteins P and Q, two acidic chitinases from tobacco.106
Oxidative tyrosylation of high density lipoprotein by peroxidase enhances cholesterol removal from cultured fibroblasts and macrophage foam cells.106
From residue coevolution to protein conformational ensembles and functional dynamics106
Induction of acetylcholine receptors on cultured skeletal muscle by a factor extracted from brain and spinal cord.106
MscS-Like10 is a stretch-activated ion channel from Arabidopsis thaliana with a preference for anions106
Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology106
Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells.106
Direct measurement of nitric oxide generation from nitric oxide synthase106
Functional and topological diversity of LOV domain photoreceptors106
Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior106
Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.106
Thalamocortical synchronization during induction and emergence from propofol-induced unconsciousness106
Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus.106
Auditory capacities in Middle Pleistocene humans from the Sierra de Atapuerca in Spain106
Persistent metabolic youth in the aging female brain105
Detection of a bioluminescent milky sea from space105
Purification and Some Characteristics of 5S DNA from Xenopus laevis105
Stability of the A15 phase in diblock copolymer melts105
MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex105
Oscillatory dynamics in a bacterial cross-protection mutualism105
A salivary effector enables whitefly to feed on host plants by eliciting salicylic acid-signaling pathway105
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway105
Evaluation of radiation doses and associated risk from the Fukushima nuclear accident to marine biota and human consumers of seafood105
Callatostatins: neuropeptides from the blowfly Calliphora vomitoria with sequence homology to cockroach allatostatins.105
Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A105
Gene flow by pollen into small populations: Data from experimental and natural stands of wild radish105
A heat shock gene from Saccharomyces cerevisiae encoding a secretory glycoprotein.105
A 12,000-year-old Shaman burial from the southern Levant (Israel)105
Adenosine release from stimulated mast cells.105
Covariation of diet and gut microbiome in African megafauna105
Disintermediating your friends: How online dating in the United States displaces other ways of meeting105
GEMM-I riboswitches from Geobacter sense the bacterial second messenger cyclic AMP-GMP105
From single drug targets to synergistic network pharmacology in ischemic stroke105
Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library105
Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature105
Induction of prostaglandin E synthesis in normal and neoplastic macrophages: role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation.105
Polynesian origins: Insights from the Y chromosome105
An early role for Sonic hedgehog from foregut endoderm in jaw development: Ensuring neural crest cell survival105
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.105
Mechanosensitivity of cultured ciliated cells from the mammalian respiratory tract: implications for the regulation of mucociliary transport.105
Isolation of a protein scaffold from mitotic HeLa cell chromosomes105
How the Dorsal gradient works: Insights from postgenome technologies105
Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes105
Chronic, sublethal effects of high temperatures will cause severe declines in southern African arid-zone birds during the 21st century105
Simultaneous identification of specifically interacting paralogs and interprotein contacts by direct coupling analysis105
A classification of spin frustration in molecular magnets from a physical study of large odd-numbered-metal, odd electron rings105
CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-κB translocation105
Identification of peptides from brain and pituitary of Cpe fat /Cpe fat mice105
Environmental enrichment extends ocular dominance plasticity into adulthood and protects from stroke-induced impairments of plasticity105
α-Hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis105
Control of ColE1 DNA replication: the rop gene product negatively affects transcription from the replication primer promoter.105
Inhibin A-subunit cDNAs from porcine ovary and human placenta.104
Improvement in municipal wastewater treatment alters lake nitrogen to phosphorus ratios in populated regions104
Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin?104
Hydrodynamic narrowing of tubes extruded from cells104
Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling104
Why green “climate gentrification” threatens poor and vulnerable populations104
Higher macrophage inflammatory protein (MIP)-1α and MIP-1β levels from CD8+T cells are associated with asymptomatic HIV-1 infection104
Intermittent collective dynamics emerge from conflicting imperatives in sheep herds104
Cloning and engineering of the cinnamycin biosynthetic gene cluster from Streptomyces cinnamoneus cinnamoneus DSM 40005104
Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains.104
Characterization of a gene from a tomato pathogen determining hypersensitive resistance in non-host species and genetic analysis of this resistance in bean104
Renewable electricity storage using electrolysis104
High-pressure highly reduced nitrides and oxides from chromitite of a Tibetan ophiolite104
Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase.104
Escherichia coli contains a soluble ATP-dependent protease (Ti) distinct from protease La.104
Unique features of the nitrogenase VFe protein from Azotobacter vinelandii104
Machine learning uncovers the most robust self-report predictors of relationship quality across 43 longitudinal couples studies104
Nucleotide sequence of the S-2 mitochondrial DNA from the S cytoplasm of maize104
The advent of animals: The view from the Ediacaran104
The mouse organellar biogenesis mutant buff results from a mutation in Vps33a , a homologue of yeast vps33 and Drosophila104
Acceleration of diabetic wound healing using a novel protease–anti-protease combination therapy104
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3 + regulatory T cells104
Evidence for a gonadotropin from nonpregnant subjects that has physical, immunological, and biological similarities to human chorionic gonadotropin.104
Antisera against a guanine nucleotide binding protein from retina cross-react with the beta subunit of the adenylyl cyclase-associated guanine nucleotide binding proteins, Ns and Ni.104
Earliest evidence for caries and exploitation of starchy plant foods in Pleistocene hunter-gatherers from Morocco104
Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries.104
Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: Role of epsilon protein kinase C104
Mitogenic leukoagglutinin from Phaseolus vulgaris binds to a pentasaccharide unit in N-acetyllactosamine-type glycoprotein glycans.104
Mechanism of Action of Ribonuclease H Isolated from Avian Myeloblastosis Virus and Escherichia coli104
Identification and characterization of hematopoietic stem cells from the yolk sac of the early mouse embryo.104
Receptor-mediated chitin perception in legume roots is functionally separable from Nod factor perception104
Hepatitis B virus capsid particles are assembled from core-protein dimer precursors.104
Simple method for constructing phylogenetic trees from distance matrices.104
Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site104
Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis104
Cloning of a receptor for amphibian [Phe13]bombesin distinct from the receptor for gastrin-releasing peptide: identification of a fourth bombesin receptor subtype (BB4).104
Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains104
Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.104
Amino-terminal sequences of two polypeptides from human serum with nonsuppressible insulin-like and cell-growth-promoting activities: evidence for structural homology with insulin B chain.104
Pyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon, Pyrococcus furiosus , functions as a CoA-dependent pyruvate decarboxylase104
A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel104
Insecticide resistance resulting from an absence of target-site gene product103
Reactive school closure weakens the network of social interactions and reduces the spread of influenza103
Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndro103
Primary endosymbiosis events date to the later Proterozoic with cross-calibrated phylogenetic dating of duplicated ATPase proteins103
Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry.103
Na,K-ATPase transport from endoplasmic reticulum to Golgi requires the Golgi spectrin–ankyrin G119 skeleton in Madin Darby canine kidney cells103
Molecular evolution of integrins: Genes encoding integrin β subunits from a coral and a sponge103
Excited-state dynamics in photosystem II: Insights from the x-ray crystal structure103
Protein dissociation from GRP78 and secretion are blocked by depletion of cellular ATP levels.103
A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier103
Evidence that insect embryogenesis is regulated by ecdysteroids released from yolk proteins.103
Lantibiotics from Geobacillus thermodenitrificans103
Disparate rates, differing fates: tempo and mode of evolution changed from the Precambrian to the Phanerozoic.103
Climate-driven regime shifts in a mangrove–salt marsh ecotone over the past 250 years103
Identification of the VERNALIZATION 4 gene reveals the origin of spring growth habit in ancient wheats from South Asia103
Functional divisions for visual processing in the central brain of flying Drosophila103
Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo<103
Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor103
Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.103
Protein transduction from retroviral Gag precursors103
Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos.103
Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch103
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1103
Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis103
Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain103
Detecting larval export from marine reserves103
Dynamic cluster formation determines viscosity and diffusion in dense protein solutions103
An R2R3 MYB transcription factor confers brown planthopper resistance by regulating the phenylalanine ammonia-lyase pathway in rice103
Mammalian Period represses and de-represses transcription by displacing CLOCK–BMAL1 from promoters in a Cryptochrome-dependent manner103
Evolution of chloroplast retrograde signaling facilitates green plant adaptation to land103
Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids103
The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway103
The last eukaryotic common ancestor (LECA): Acquisition of cytoskeletal motility from aerotolerant spirochetes in the Proterozoic Eon103
Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells.103
Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage.103
T7 phage display: A novel genetic selection system for cloning RNA-binding proteins from cDNA libraries103
Spatial gradients in Clovis-age radiocarbon dates across North America suggest rapid colonization from the north103
A New Synthetic RNA-Dependent DNA Polymerase from Human Tissue Culture Cells103
Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein.102
Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori102
Isolation and spectral characterization of photochemical reaction centers from the thermophilic green bacterium Chloroflexus aurantiacus strain J-10-f1102
Regulation of Nucleoside Cyclic 3′:5′-Monophosphate Phosphodiesterase Activity from Rat Brain by a Modulator and Ca 2+102
The evolution of vertebrate blood coagulation as viewed from a comparison of puffer fish and sea squirt genomes102
A crystallographic map of the transition from B-DNA to A-DNA102
Climate shapes and shifts functional biodiversity in forests worldwide102
Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients.102
In Vitro Assembly of Neurospora Assimilatory Nitrate Reductase from Protein Subunits of a Neurospora Mutant and the Xan102
Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex102
Heat shock protein 90 from Escherichia coli collaborates with the DnaK chaperone system in client protein remodeling102
Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus102
Protease La from Escherichia coli hydrolyzes ATP and proteins in a linked fashion.102
α-Tocopherol transfer protein stimulates the secretion of α-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway102
tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation process.102
Complete congruence between gene diversity estimates derived from genotypic data at enzyme and random amplified polymorphic DNA loci in black spruce.102
Endogenous circadian rhythm in human motor activity uncoupled from circadian influences on cardiac dynamics102
Trans-activation function of a 3' truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissues.102
Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species.102
Importing food damages domestic environment: Evidence from global soybean trade102
The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family102
Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse102
Initiation of the alternative pathway of complement: recognition of activators by bound C3b and assembly of the entire pathway from six isolated proteins.102
Probing the instabilities in the dynamics of helical fragments from mouse PrP C102
Molecular-timetable methods for detection of body time and rhythm disorders from single-time-point genome-wide expression profiles102
Genetic variation across the human olfactory receptor repertoire alters odor perception102
Cytosolic calcium transients from the beating mammalian heart.102
Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells.102
Expert assessments of the cost and expected future performance of proton exchange membrane fuel cells for vehicles102
Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp1.102
The subtilisin E gene of Bacillus subtilis is transcribed from a sigma 37 promoter in vivo.102
Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.102
Climate change and residential electricity consumption in the Yangtze River Delta, China102
The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity102
Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein102
Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice102
A possible evolutionary origin for the Mn 4 cluster of the photosynthetic water oxidation complex from natural MnO 2 precipitates 102
Electron microscopic heteroduplex analysis of "killer" double-stranded RNA species from yeast.102
Expression of Plasmodium falciparum blood-stage antigens in Escherichia coli: detection with antibodies from immune humans.102
Crystal structure of 12-oxophytodienoate reductase 3 from tomato: Self-inhibition by dimerization102
Fluidity of the lipid domain of cell wall from Mycobacterium chelonae.102
Molybdenum cofactors from molybdoenzymes and in vitro reconstitution of nitrogenase and nitrate reductase101
Unlocking evidence of early diet from tooth enamel101
Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors101
An open challenge to advance probabilistic forecasting for dengue epidemics101
Directional pumping of water and oil microdroplets on slippery surface101
Characterization of a platelet-activating factor receptor antagonist isolated from haifenteng (Piper futokadsura): specific inhibition of in vitro and in vivo platelet-activating factor-induced effect101
Striking sequence similarity in inter- and intra-specific comparisons of class I SLG alleles from Brassica oleracea and Br101
Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair101
The central structural feature of the membrane fusion protein subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil101
Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain101
A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators101
FLUOROGENIC SUBSTRATES FOR β-D-GALACTOSIDASES AND PHOSPHATASES DERIVED FROM FLUORESCEIN (3, 6-DIHYDROXYFLUORAN) AND ITS MONOMETHYL ETHER101
Evolution of an antifreeze protein by neofunctionalization under escape from adaptive conflict101
Ultraviolet pigments in birds evolved from violet pigments by a single amino acid change101
Distinguishing Reverse Transcriptase of an RNA Tumor Virus from Other Known DNA Polymerases101
Post-2020 biodiversity targets need to embrace climate change101
Female exogamy and gene pool diversification at the transition from the Final Neolithic to the Early Bronze Age in central Europe101
Highly divergent molecular variants of human T-lymphotropic virus type I from isolated populations in Papua New Guinea and the Solomon Islands.101
Toward an international definition of citizen science101
Antidepressant-relevant concentrations of the ketamine metabolite (2 R ,6 R )-hydroxynorketamine do not block NMDA receptor function101
Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR101
Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells101
Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma101
Photocatalysis and the origin of life: Synthesis of nucleoside bases from formamide on TiO 2 (001) single surfaces101
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts101
Vasoactive intestinal polypeptide in brain: localization in and release from isolated nerve terminals.101
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control101
Identification of a nonprocessive telomerase activity from mouse cells.101
Activation of GCN2 by the ribosomal P-stalk101
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells101
AP-4 mediates export of ATG9A from the trans -Golgi network to promote autophagosome formation101
Deep learning for inferring gene relationships from single-cell expression data101
Symbiotic organs shaped by distinct modes of genome evolution in cephalopods101
Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.101
Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human101
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor101
Site of aminoacylation of tRNAs from Escherichia coli with respect to the 2'- or 3'-hydroxyl group of the terminal adenosine.101
Association of single-stranded transferred DNA from Agrobacterium tumefaciens with tobacco cells.101
Infrared spectroelectrochemistry of bacteriochlorophylls and bacteriopheophytins: Implications for the binding of the pigments in the reaction center from photosynthetic bacteria100
Gray Matter Age Prediction as a Biomarker for Risk of Dementia100
Transposition of the mariner element from Drosophila mauritiana in zebrafish100
Accurate molecular polarizabilities with coupled cluster theory and machine learning100
Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes.100
Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma100
Inducible gene expression from the plastid genome by a synthetic riboswitch100
Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral blood lymphocytes and antibodies to the adducts in serum from coke oven workers.100
A minute circular DNA from Escherichia coli 15.100
Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy100
Serotonin receptor cDNA cloned from Lymnaea stagnalis.100
A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia100
The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains100
Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter.100
Body size, body proportions, and encephalization in a Middle Pleistocene archaic human from northern China100
Heavy metals induce rapid calcium release from sarcoplasmic reticulum vesicles isolated from skeletal muscle.100
Reconstitution of thermostable ATPase capable of energy coupling from its purified subunits.100
Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer100
Fluctuation Spectroscopy: Determination of Chemical Reaction Kinetics from the Frequency Spectrum of Fluctuations100
VEGFR3 does not sustain retinal angiogenesis without VEGFR2100
Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug100
Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation100
Characterization of somatomedins from human fetal brain: identification of a variant form of insulin-like growth factor I.100
Middle Pleistocene lower back and pelvis from an aged human individual from the Sima de los Huesos site, Spain100
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice.100
Annexin-like protein from Arabidopsis thaliana rescues delta oxyR mutant of Escherichia coli from H2O2 stress.100
Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma.100
High nitrous oxide fluxes from rice indicate the need to manage water for both long- and short-term climate impacts100
Three-dimensional distribution of transient interactions in the nuclear pore complex obtained from single-molecule snapshots100
A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca 2+ influx100
Exogenous glutathione protects intestinal epithelial cells from oxidative injury.100
Germacrene C synthase fromLycopersicon esculentumcv. VFNT Cherry tomato: cDNA isolation, characterization, and bacterial expression of the multiple product sesquiterpene cyclase100
A novel mycovirus from Aspergillus fumigatus contains four unique dsRNAs as its genome and is infectious as dsRNA100
Isolation of infectious human T-cell leukemia/lymphotropic virus type III (HTLV-III) from patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) and from healthy carrier100
Microtubule binding distinguishes dystrophin from utrophin99
Mammal diversity will take millions of years to recover from the current biodiversity crisis99
Two sequence motifs from HIF-1α bind to the DNA-binding site of p5399
Biology in the Anthropocene: Challenges and insights from young fossil records99
Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding99
Nutritional and greenhouse gas impacts of removing animals from US agriculture99
Aldehydes and sugars from evolved precometary ice analogs: Importance of ices in astrochemical and prebiotic evolution99
Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes99
Nitric oxide production in islets from nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process.99
Neural indicators of perceptual variability of pain across species99
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa , defines a third class of sulfatases99
Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain.99
Characterization of iron superoxide dismutase cDNAs from plants obtained by genetic complementation in Escherichia coli.99
Analysis of optical spectra from single crystals of Rhodopseudomonas viridis reaction centers99
Permian vegetational Pompeii from Inner Mongolia and its implications for landscape paleoecology and paleobiogeography of Cathaysia99
A developmentally regulated mRNA from 3T3 adipocytes encodes a novel serine protease homologue.99
Frequency-dependent release of peptide cotransmitters from identified cholinergic motor neurons in Aplysia.99
PEPTIDYL TRANSFERS IN GRAMICIDIN S BIOSYNTHESIS FROM ENZYME-BOUND THIOESTER INTERMEDIATES99
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase99
Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues.99
Transcriptomic analysis of field-droughted sorghum from seedling to maturity reveals biotic and metabolic responses99
Biological embedding of experience: A primer on epigenetics99
Interference fine structure and sarcomere length dependence of the axial x-ray pattern from active single muscle fibers99
Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma.99
Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein99
Regeneration of whole fertile plants from 30,000-y-old fruit tissue buried in Siberian permafrost99
HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs99
Macroevolutionary speciation rates are decoupled from the evolution of intrinsic reproductive isolation in Drosophila and birds99
Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene.99
Production of calves by transfer of nuclei from cultured inner cell mass cells.99
Remarkable nucleation and growth of ultrafine particles from vehicular exhaust99
The control of hematopoiesis and leukemia: from basic biology to the clinic.99
Primary structures of the precursor and mature forms of stearoyl-acyl carrier protein desaturase from safflower embryos and requirement of ferredoxin for enzyme activity.99
The mixed effects of online diversity training99
Allurin, a 21-kDa sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins99
Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs.99
Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus99
Accelerated degradation of acetylcholine receptor from cultured rat myotubes with myasthenia gravis sera and globulins.98
Cloning and expression of cDNA for the luciferase from the marine ostracod Vargula hilgendorfii.98
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum98
Multiomics resolution of molecular events during a day in the life of Chlamydomonas98
Cascading trend of Early Paleozoic marine radiations paused by Late Ordovician extinctions98
Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry98
Effects of rapid evolution on species coexistence98
High Arctic Holocene temperature record from the Agassiz ice cap and Greenland ice sheet evolution98
The avocado genome informs deep angiosperm phylogeny, highlights introgressive hybridization, and reveals pathogen-influenced gene space adaptation98
Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam98
West African monsoon dynamics inferred from abrupt fluctuations of Lake Mega-Chad98
Fast and accurate HLA typing from short-read next-generation sequence data with xHLA98
The final acylation step in Taxol biosynthesis: Cloning of the taxoid C13-side-chain N -benzoyltransferase from Taxus98
Chromogranin B (secretogranin I) promotes sorting to the regulated secretory pathway of processing intermediates derived from a peptide hormone precursor.98
Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus.98
Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis98
Purification and characterization of three types of protein kinase C from rabbit brain cytosol.98
Crystal structure of glycoprotein C from Rift Valley fever virus98
Molecular spherical nucleic acids98
A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes98
Mangroves shelter coastal economic activity from cyclones98
Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients with humoral hypercalcemia of malig98
cDNA cloning and expression of murine macrophage colony-stimulating factor from L929 cells.98
Biodegradable nanofiber-based piezoelectric transducer98
Molecular cloning, tissue distribution, and expression of a 14-kDa bile acid-binding protein from rat ileal cytosol.98
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition98
Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain.98
Three-dimensional structures of aspartate carbamoyltransferase from Escherichia coli and of its complex with cytidine triphosphate.98
Nucleotide sequence and expression of the mercurial-resistance operon from Staphylococcus aureus plasmid pI258.98
Release of protein A from the cell wall of Staphylococcus aureus98
Diverse GPCRs exhibit conserved water networks for stabilization and activation98
The iron deficiency response in Arabidopsis thaliana requires the phosphorylated transcription factor URI98
Highly scalable multichannel mesh electronics for stable chronic brain electrophysiology98
Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex98
Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA.98
DNA polymerase ζ cooperates with polymerases κ and ι in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients98
TNF-α from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection98
Production of healthy cloned mice from bodies frozen at −20°C for 16 years98
The thermodynamic H + /ATP ratios of the H + -ATPsynthases from chloroplasts and Escherichia coli98
Structure of the light-harvesting bacteriochlorophyll c assembly in chlorosomes from Chlorobium limicola determined by solid-state NMR97
Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity97
N,N'-dicyclohexylcarbodiimide binds specifically to a single glutamyl residue of the proteolipid subunit of the mitochondrial adenosinetriphosphatases from Neurospora crassa and Saccharomyces cerevisi97
Receptors from Glucocorticoid-Sensitive Lymphoma Cells and Two Classes of Insensitive Clones: Physical and DNA-Binding Properties97
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer97
Dexamethasone 21-mesylate: an affinity label of glucocorticoid receptors from rat hepatoma tissue culture cells.97
Reduced fitness in progeny from old parents in a natural population97
RNAi is a critical determinant of centromere evolution in closely related fungi97
Discussing global warming leads to greater acceptance of climate science97
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice97
Amazon deforestation drives malaria transmission, and malaria burden reduces forest clearing97
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter97
Photoelectric conversion on Earth’s surface via widespread Fe- and Mn-mineral coatings97
Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone97
Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease97
A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain.97
CD4+CD25+regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity97
Isolation and sequence of the gene for the large subunit of ribulose-1,5-bisphosphate carboxylase from the cyanobacterium Anabaena 712097
Complement-fixing antibodies in sera of human and nonhuman primates to viral antigens derived from Burkitt's lymphoma cells.97
Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism97
In vitro generation of hematopoietic stem cells from an embryonic stem cell line.97
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan97
Single channel currents from excised patches of muscle membrane.97
Root-specific camalexin biosynthesis controls the plant growth-promoting effects of multiple bacterial strains97
Establishment and characterization of 10 cell lines derived from patients with adult T-cell leukemia.97
Evolutionarily informed deep learning methods for predicting relative transcript abundance from DNA sequence97
Aspirin-triggered proresolving mediators stimulate resolution in cancer97
Cultured psoriatic fibroblasts from involved and uninvolved sites have a partial but not absolute resistance to the proliferation-inhibition activity of 1,25-dihydroxyvitamin D3.97
Divergent mtDNA lineages of goats in an Early Neolithic site, far from the initial domestication areas97
Parallelism of amino acid changes at the RH1 affecting spectral sensitivity among deep-water cichlids from Lakes Tanganyika and Malawi97
Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus97
An Epstein-Barr virus immediate-early gene product trans-activates gene expression from the human immunodeficiency virus long terminal repeat.97
Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine97
Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor.97
Preservation of viral genomes in 700-y-old caribou feces from a subarctic ice patch97
A zinc protein isolated from human parotid saliva.97
Novel RNA polymerase sigma factor from Bacillus subtilis.97
Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence97
Role of economics in analyzing the environment and sustainable development97
Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia.97
Cone photoreceptor classification in the living human eye from photostimulation-induced phase dynamics97
The N-terminal domain of PsaF: Precise recognition site for binding and fast electron transfer from cytochromec6and plastocyanin to photosystem I ofChlamydomonas reinhardtii97
Millisecond time-resolved changes in x-ray reflections from contracting muscle during rapid mechanical transients, recorded using synchrotron radiation.97
Three-dimensional structure of the quorum-quenching N -acyl homoserine lactone hydrolase from Bacillus thuringiensis97
Primary structure of blood coagulation factor XIIIa (fibrinoligase, transglutaminase) from human placenta.96
The Molecular Weight of the Major Glycoprotein from the Human Erythrocyte Membrane96
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules96
Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome t96
Rapidly declining remarkability of temperature anomalies may obscure public perception of climate change96
Herbicide resistance in Chlamydomonas reinhardtii results from a mutation in the chloroplast gene for the 32-kilodalton protein of photosystem II96
Novel pathways for fuels and lubricants from biomass optimized using life-cycle greenhouse gas assessment96
Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons96
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation96
The folding pathway of a protein at high resolution from microseconds to seconds96
The ets sequence from the transforming gene of avian erythroblastosis virus, E26, has unique domains on human chromosomes 11 and 21: both loci are transcriptionally active.96
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels96
GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence.96
Catalytic hydrogen evolution from a covalently linked dicobaloxime96
Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells.96
A self-assembled Ru–Pt metallacage as a lysosome-targeting photosensitizer for 2-photon photodynamic therapy96
Microsatellite evolution inferred from human– chimpanzee genomic sequence alignments96
Transcriptomic atlas of mushroom development reveals conserved genes behind complex multicellularity in fungi96
Structure of the subunit c oligomer in the F 1 F o ATP synthase: Model derived from solution structure of the monomer and cross-li96
HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT296
Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins.96
Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.96
Evolution of the major histocompatibility complex: isolation of class II A cDNA clones from the cartilaginous fish.96
WNK1 -related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron96
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin96
Interaction of the histone (H3-H4)2 tetramer of the nucleosome with positively supercoiled DNA minicircles: Potential flipping of the protein from a left- to a right-handed superhelical form.96
Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma96
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.96
Restoration of spermatogenesis by lentiviral gene transfer: Offspring from infertile mice96
Sleep-promoting effects of cerebrospinal fluid from sleep-deprived goats.96
Stability-driven nonnegative matrix factorization to interpret spatial gene expression and build local gene networks96
α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease96
A double-stranded RNA element from a hypovirulent strain of Rhizoctonia solani occurs in DNA form and is genetically related to the pentafunctional AROM protein of the s96
Functional acetylcholine receptor from Torpedo marmorata in planar membranes.96
Evolution of the vasopressin/oxytocin superfamily: characterization of a cDNA encoding a vasopressin-related precursor, preproconopressin, from the mollusc Lymnaea stagnalis.96
Procoat, the precursor of M13 coat protein, requires an electrochemical potential for membrane insertion.96
Separation of the arterial wall from blood contact using hydrogel barriers reduces intimal thickening after balloon injury in the rat: The roles of medial and luminal factors in arterial healing96
Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.96
Biologically inspired LED lens from cuticular nanostructures of firefly lantern96
LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson’s disease96
Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function.96
Topography and stoichiometry of acidic proteins in large ribosomal subunits from Artemia salina as determined by crosslinking.96
Mapping the conformational transition in Src activation by cumulating the information from multiple molecular dynamics trajectories96
Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells96
Is the Gene the Unit of Selection? Evidence from Two Experimental Plant Populations95
Variable G protein determinants of GPCR coupling selectivity95
Identification and sequence analysis of a second form of prolactin receptor by molecular cloning of complementary DNA from rabbit mammary gland.95
Purification and characterization of initiation factor IF-E3 from rabbit reticulocytes.95
Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST95
Homology among acid proteases: comparison of crystal structures at 3A resolution of acid proteases from Rhizopus chinensis and Endothia parasitica.95
Ribosomal protein RPL26 is the principal target of UFMylation95
An exogenous retrovirus isolated from koalas with malignant neoplasias in a US zoo95
Similarity of secretory protein I from parathyroid gland to chromogranin A from adrenal medulla.95
Proof for a nonproteinaceous calcium-selective channel in Escherichia coli by total synthesis from ( R )-3-hydroxybutanoic acid and inorga95
Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 Å resolution95
Phytochelatin production by marine phytoplankton at low free metal ion concentrations: laboratory studies and field data from Massachusetts Bay.95
Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering.95
Strategy for the mass spectrometric verification and correction of the primary structures of proteins deduced from their DNA sequences.95
Molecular dynamics of an α-helical polypeptide: Temperature dependence and deviation from harmonic behavior95
glh-1, a germ-line putative RNA helicase from Caenorhabditis, has four zinc fingers.95
Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.95
A forager–herder trade-off, from broad-spectrum hunting to sheep management at Aşıklı Höyük, Turkey95
TWO METABOLICALLY ACTIVE PEPTIDES FROM PORCINE PITUITARY GLANDS95
An oscillator model better predicts cortical entrainment to music95
Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence95
Double-negative T cells remarkably promote neuroinflammation after ischemic stroke95
A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.95
Binding of small acid-soluble spore proteins from Bacillus subtilis changes the conformation of DNA from B to A.95
A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities.95
Inducers of interferon and host resistance. 3. Double-stranded RNA from reovirus type 3 virions (reo 3-RNA).95
ATP-Dependent and Cyclic AMP-Dependent Activation of Rat Adipose Tissue Lipase by Protein Kinase from Rabbit Skeletal Muscle95
Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus95
Bioelectronic neural pixel: Chemical stimulation and electrical sensing at the same site95
Exceptionally preserved crustaceans from western Canada reveal a cryptic Cambrian radiation95
Cloning by function: an alternative approach for identifying yeast homologs of genes from other organisms.95
Precious metal recovery from electronic waste by a porous porphyrin polymer95
Crystal structure of glycoprotein E2 from bovine viral diarrhea virus95
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease95
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models95
Connectional architecture of a mouse hypothalamic circuit node controlling social behavior95
Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4.95
Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation95
Evidence for selenocysteine coordination to the active site nickel in the [NiFeSe]hydrogenases from Desulfovibrio baculatus.95
Rapid increase in Asian bottles in the South Atlantic Ocean indicates major debris inputs from ships95
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.95
RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation95
Secretion of Escherichia coli beta-lactamase from Bacillus subtilis by the aid of alpha-amylase signal sequence.95
Can free energy be transduced from electric noise?95
On the evolution and physiology of cable bacteria95
Na channel inactivation from open and closed states94
Agency plus automation: Designing artificial intelligence into interactive systems94
Small-molecule–directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells94
12S,20-dihydroxyicosatetraenoic acid: a new icosanoid synthesized by neutrophils from 12S-hydroxyicosatetraenoic acid produced by thrombin- or collagen-stimulated platelets.94
Deletion of the Cel48S cellulase from Clostridium thermocellum94
Occurrence of enzymes involved in biosynthesis of indole-3-acetic acid from indole-3-acetonitrile in plant-associated bacteria, Agrobacterium and Rhizobium.94
Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays94
Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum.94
Nascent polypeptide chains emerge from the exit domain of the large ribosomal subunit: immune mapping of the nascent chain.94
Elephants can determine ethnicity, gender, and age from acoustic cues in human voices94
AN XX/XY HUMAN HERMAPHRODITE RESULTING FROM DOUBLE FERTILIZATION94
Isolation of a transposable element from Neurospora crassa.94
Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs94
Silencing of natural transformation by an RNA chaperone and a multitarget small RNA94
Atmospheric composition 1 million years ago from blue ice in the Allan Hills, Antarctica94
Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells94
Disrupting theIL-4gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-β production by fibroblasts94
Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus94
A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver.94
Limited cleavage of cellular fibronectin by plasminogen activator purified from transformed cells.94
Biological and Molecular Evidence for the Transgenosis of Genes from Bacteria to Plant Cells94
Control of somite patterning by signals from the lateral plate.94
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells94
Pore condensation and freezing is responsible for ice formation below water saturation for porous particles94
Gliogenesis in the outer subventricular zone promotes enlargement and gyrification of the primate cerebrum94
Six hundred years of South American tree rings reveal an increase in severe hydroclimatic events since mid-20th century94
Primary structure of the (1→3,1→4)-β-D-glucan 4-glucohydrolase from barley aleurone94
Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death94
Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists94
Nuclear localization of the C1 factor (host cell factor) in sensory neurons correlates with reactivation of herpes simplex virus from latency94
Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin.94
THE EFFECT OF HYDRODYNAMIC SHEAR ON THE DEOXYRIBONUCLEIC ACID FROM T 2 AND T 4 BACTERIOPHAGES94
Demonstration of inter- and intraspecies differences in serotonin binding sites by antibodies from an autistic child.94
Unexpected host dependency of Antarctic Nanohaloarchaeota94
Evoked release of acetylcholine from the growing embryonic neuron.94
Resolving the transition from negative to positive blood oxygen level-dependent responses in the developing brain93
Multibioinspired slippery surfaces with wettable bump arrays for droplets pumping93
HOMOLOGY BETWEEN RNA FROM ROUS SARCOMA VIRUS AND DNA FROM ROUS SARCOMA VIRUS-INFECTED CELLS93
Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity93
Awareness-driven behavior changes can shift the shape of epidemics away from peaks and toward plateaus, shoulders, and oscillations93
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage93
Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata.93
Micrometeorites from the Transantarctic Mountains93
Phosphorylation of the fused protein kinase in response to signaling from hedgehog.93
Translation of Brome Mosaic Viral Ribonucleic Acid in a Cell-Free System Derived from Wheat Embryo93
Crystal structure of a bovine neurophysin II dipeptide complex at 2.8 A determined from the single-wavelength anomalous scattering signal of an incorporated iodine atom.93
A FATTY ACID SYNTHETASE FROM E. COLI93
Solution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19 E -geissoschizine93
Characterization and cDNA cloning of the pheromone-binding protein from the tobacco hornworm, Manduca sexta: a tissue-specific developmentally regulated protein.93
Cloned endogenous retroviral sequences from human DNA.93
Isolation and characterization of delta-subspecies of protein kinase C from rat brain.93
Inference from Inadequate and Inaccurate Data, I93
GWAS with principal component analysis identifies a gene comprehensively controlling rice architecture93
Diversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes93
Anti–CTLA-4 therapy requires an Fc domain for efficacy93
Ion permeation through a Cl -selective channel designed from a CLC Cl /H + exchanger93
Tetrapyrrole signal as a cell-cycle coordinator from organelle to nuclear DNA replication in plant cells93
A spliced leader is present on a subset of mRNAs from the human parasite Schistosoma mansoni.93
Toll-like receptor signaling controls reactivation of KSHV from latency93
Mimicking enzyme evolution by generating new (βα) 8 -barrels from (βα) 4 -half-barrels93
A functional cellulose synthase from ascidian epidermis93
Unique organization of photosystem I–light-harvesting supercomplex revealed by cryo-EM from a red alga93
A Three-Dimensional Molecular Assembly Model of a Lipoprotein from the Escherichia coli Outer Membrane93
The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1.93
Population genetics of ecological communities with DNA barcodes: An example from New Guinea Lepidoptera93
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology93
Alanine, not ammonia, is excreted from N 2 -fixing soybean nodule bacteroids93
A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae93
Assembly of the cnidarian camera-type eye from vertebrate-like components93
Self-renewing endometrial epithelial organoids of the human uterus93
Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies93
Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 293
Data visualization literacy: Definitions, conceptual frameworks, exercises, and assessments93
Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss93
Isolation and Partial Characterization of α- and β-Tubulin from Outer Doublets of Sea-Urchin Sperm and Microtubules of Chick-Embryo Brain93
Aspartic acid racemization in heavy molecular weight crystallins and water insoluble protein from normal human lenses and cataracts.93
Male-sterility induction in transgenic tobacco plants with an unedited atp9 mitochondrial gene from wheat.93
Protein ranking: From local to global structure in the protein similarity network93
Macromolecular crowding allows blunt-end ligation by DNA ligases from rat liver or Escherichia coli.93
Volcanic history of the Imbrium basin: A close-up view from the lunar rover Yutu93
Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries.93
Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models93
UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y 2  receptor93
( 2R,6R )-hydroxynorketamine exerts mGlu 2 receptor-dependent antidepressant actions93
Complete amino acid sequence of human thyroxine-binding globulin deduced from cloned DNA: close homology to the serine antiproteases.93
Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children93
DNA sequence from the histidine operon control region: seven histidine codons in a row.92
Initiation of protein synthesis from a termination codon.92
Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH192
Highly conductive and chemically stable alkaline anion exchange membranes via ROMP of trans -cyclooctene derivatives92
Bioinspired supramolecular fibers drawn from a multiphase self-assembled hydrogel92
SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors92
Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-192
Direct visualization of glutamate transporter elevator mechanism by high-speed AFM92
Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation92
Data gaps and opportunities for comparative and conservation biology92
An Endonuclease from Escherichia coli That Acts Preferentially on UV-Irradiated DNA and Is Absent from the uvrA and uvrB92
Complete replication of an animal virus and maintenance of expression vectors derived from it in Saccharomyces cerevisiae.92
Molecular hydrophobicity at a macroscopically hydrophilic surface92
Rhythmic alternating patterns of brain activity distinguish rapid eye movement sleep from other states of consciousness92
A fourth class of theta-replicating plasmids: the pAM beta 1 family from gram-positive bacteria.92
A possible glycine radical in anaerobic ribonucleotide reductase from Escherichia coli: nucleotide sequence of the cloned nrdD gene.92
Numerical thought with and without words: Evidence from indigenous Australian children92
Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA.92
Recent development of the neutral theory viewed from the Wrightian tradition of theoretical population genetics.92
Human neutrophil elastase releases cell surface mucins from primary cultures of hamster tracheal epithelial cells.92
Experimental support for the evolution of symmetric protein architecture from a simple peptide motif92
Description of two genera and species of late Eocene Anthropoidea from Egypt.92
Isolation of a 5S RNA-Protein Complex from Mammalian Ribosomes92
Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk92
Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus92
How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory92
Coexistence of ribbon and helical fibrils originating from hIAPP 20–29 revealed by quantitative nanomechanical atomic force microscopy92
The hemochromatosis protein HFE inhibits iron export from macrophages92
Cortical route for facelike pattern processing in human newborns92
Chiral structures from achiral liquid crystals in cylindrical capillaries92
Exceptionally preserved juvenile megalosauroid theropod dinosaur with filamentous integument from the Late Jurassic of Germany92
Multifunctional graphene supports for electron cryomicroscopy92
Lattice thermal conductivity of lower mantle minerals and heat flux from Earth’s core92
Universal method for robust detection of circadian state from gene expression92
Two additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable element.92
Isolation and sequence of cDNA encoding a cytochrome P-450 from an insecticide-resistant strain of the house fly, Musca domestica.92
DIRECT EVIDENCE FOR THE TRANSFER OF MATERIALS FROM SYMBIOTIC ALGAE TO THE TISSUES OF A COELENTERATE92
Transcriptome-wide analysis of blood vessels laser captured from human skin and chronic wound-edge tissue92
A topoisomerase from Escherichia coli related to DNA gyrase.92
Inhibition of Release of Dopamine-β-Hydroxylase and Norepinephrine from Sympathetic Nerves by Colchicine, Vinblastine, or Cytochalasin-B92
Diphosphopyridine nucleotide: a cofactor for the polynucleotide-joining enzyme from Escherichia coli.92
X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors92
Elicitins from Phytophthora and basic resistance in tobacco.92
Turbulent mixing: A perspective92
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism92
Multiscale porous elastomer substrates for multifunctional on-skin electronics with passive-cooling capabilities92
Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components92
Human T-cell leukemia-lymphoma virus (HTLV) is in T but not B lymphocytes from a patient with cutaneous T-cell lymphoma.92
Separation of sequences defining basal expression from those conferring alpha gene recognition within the regulatory domains of herpes simplex virus 1 alpha genes.92
Genome-wide screen identifies host colonization determinants in a bacterial gut symbiont92
Self-organizing super-structures formed from hydrogen-bonded biimidazolate metal complexes92
Hybridization and gene flow in the mega-pest lineage of moth, Helicoverpa92
The cytochrome ba 3 oxygen reductase from Thermus thermophilus uses a single input ch92
Spontaneous spatiotemporal waves of gene expression from biological clocks in the leaf92
Free amino acids exhibit anthozoan "host factor" activity: they induce the release of photosynthate from symbiotic dinoflagellates in vitro.92
Single-molecule tracking of mRNA exiting from RNA polymerase II92
Nonrandom mating in Drosophila melanogaster laboratory populations derived from closely adjacent ecologically contrasting slopes at “Evolution Canyon”92
Characterization of invasion plasmid antigen genes (ipaBCD) from Shigella flexneri.92
Ribosomal protein S15 from Escherichia coli modulates its own translation by trapping the ribosome on the mRNA initiation loading site.92
Structure of ferredoxin I from Azotobacter vinelandii.92
rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.91
High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments91
The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site91
Extended high-frequency hearing enhances speech perception in noise91
Evolution of maize inferred from sequence diversity of an Adh2 gene segment from archaeological specimens.91
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH91
Evidence from Cameroon reveals differences in the genetic structure and histories of chimpanzee populations91
Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human.91
An archaeal antioxidant: Characterization of a Dps-like protein from Sulfolobus solfataricus91
Electrostatic complementarity in an aldose reductase complex from ultra-high-resolution crystallography and first-principles calculations91
Mobilization of T-DNA from Agrobacterium to plant cells involves a protein that binds single-stranded DNA.91
A cranium for the earliest Europeans: Phylogenetic position of the hominid from Ceprano, Italy91
Natural variation in the HAN1 gene confers chilling tolerance in rice and allowed adaptation to a temperate climate91
Double-Stranded Regions in Heterogeneous Nuclear RNA from Hela Cells91
A viral resistance gene from common bean functions across plant families and is up-regulated in a non-virus-specific manner91
Pseudouridinylation of mRNA coding sequences alters translation91
Protein stability engineering insights revealed by domain-wide comprehensive mutagenesis91
Accurate model of liquid–liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties91
The genomic basis of Red Queen dynamics during rapid reciprocal host–pathogen coevolution91
Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA.91
Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes.91
Early lineage specification defines alveolar epithelial ontogeny in the murine lung91
betawrap : Successful prediction of parallel β-helices from primary sequence reveals an association with many microbial pathogens91
N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations.91
Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster.91
Evidence from opsin genes rejects nocturnality in ancestral primates91
Cerebral cortical folding, parcellation, and connectivity in humans, nonhuman primates, and mice91
Chrysanthemyl diphosphate synthase: Isolation of the gene and characterization of the recombinant non-head-to-tail monoterpene synthase from Chrysanthemum cinerariaefolium91
Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation91
Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum91
Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling91
Transcriptomics and neuroanatomy of the clonal raider ant implicate an expanded clade of odorant receptors in chemical communication91
Site-directed mutagenesis of human beta-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cy91
Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells91
Transition from one-dimensional water to ferroelectric ice within a supramolecular architecture91
Cell spreading controls endoplasmic and nuclear calcium: A physical gene regulation pathway from the cell surface to the nucleus91
Methylation protects microRNAs from an AGO1-associated activity that uridylates 5′ RNA fragments generated by AGO1 cleavage91
Evidence for a spin-coupled binuclear iron unit at the active site of the purple acid phosphatase from beef spleen.91
The Bacillus subtilis sigL gene encodes an equivalent of sigma 54 from gram-negative bacteria.91
PREPARATION OF FOUR NEW ANTIBIOTICS FROM A MUTANT OF Streptomyces fradiae91
Contamination of refuges byBacillus thuringiensistoxin genes from transgenic maize91
Knotted DNA from bacteriophage capsids.91
Optimizing grain yields reduces CH 4 emissions from rice paddy fields90
d -Ala- d -Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligase90
Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM10190
Size distribution of particles in Saturn’s rings from aggregation and fragmentation90
The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death.90
Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis.90
The role of habitat shift in the evolution of lizard morphology: evidence from tropical  Tropidurus90
Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site90
Small molecule blockers of the Alzheimer Aβ calcium channel potently protect neurons from Aβ cytotoxicity90
Unraveling ancestry, kinship, and violence in a Late Neolithic mass grave90
ON THE IMPOSSIBILITY OF ALL OVERLAPPING TRIPLET CODES IN INFORMATION TRANSFER FROM NUCLEIC ACID TO PROTEINS90
Cytochalasin B, Its Interaction with Actin and Actomyosin from Muscle90
Predictability of human differential gene expression90
Intratumoral oxygen gradients mediate sarcoma cell invasion90
Sono-optogenetics facilitated by a circulation-delivered rechargeable light source for minimally invasive optogenetics90
Tearing of Indian mantle lithosphere from high-resolution seismic images and its implications for lithosphere coupling in southern Tibet90
Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio–venous connections90
The bioactive Taxol conformation on β-tubulin: Experimental evidence from highly active constrained analogs90
Determination of the primary amino acid sequence specifying the alpha-bungarotoxin binding site on the alpha subunit of the acetylcholine receptor from Torpedo californica.90
Ötzi's last meals: DNA analysis of the intestinal content of the Neolithic glacier mummy from the Alps90
Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line.90
Modification of age-related immune decline in mice dietarily restricted from or after midadulthood.90
Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation90
MtrB from Bacillus subtilis binds specifically to trp leader RNA in a tryptophan-dependent manner.90
Contacts between DNA gyrase and its binding site on DNA: features of symmetry and asymmetry revealed by protection from nucleases.90
Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer’s disease pathogenesis90
Self-assembly of tunable protein suprastructures from recombinant oleosin90
An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication90
Patterns of genome-wide allele-specific expression in hybrid rice and the implications on the genetic basis of heterosis90
Earliest known Oldowan artifacts at >2.58 Ma from Ledi-Geraru, Ethiopia, highlight early technological diversity90
Purification to homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits.90
Isotopic evidence for omnivory among European cave bears: Late Pleistocene Ursus spelaeus from the Peştera cu Oase, Romania90
A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus90
Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus90
Synergistic allelochemicals from a freshwater cyanobacterium90
FragBag, an accurate representation of protein structure, retrieves structural neighbors from the entire PDB quickly and accurately90
Isolation of virus-neutralizing RNAs from a large pool of random sequences.90
Mitotic recombination map of 13cen–13q14 derived from an investigation of loss of heterozygosity in retinoblastomas90
Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibers.90
Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut90
Reversibility of the Tryptophanase Reaction: Synthesis of Tryptophan from Indole, Pyruvate, and Ammonia90
Separation of Rotational Coördinates from the Schrödinger Equation for N Particles90
Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix90
Learning to predict the cosmological structure formation90
Rivers across the Siberian Arctic unearth the patterns of carbon release from thawing permafrost90
NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets90
The 30-kDa C-terminal domain of the RecB protein is critical for the nuclease activity, but not the helicase activity, of the RecBCD enzyme from  Escherichia coli89
The unusual metal clusters of nitrogenase: structural features revealed by x-ray anomalous diffraction studies of the MoFe protein from Clostridium pasteurianum.89
Twisting macromolecular chains: Self-assembly of a chiral supermolecule from nonchiral polythiophene polyanions and random-coil synthetic peptides89
Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons89
REMOVAL OF SIALIC ACID FROM THE CELL COAT IN TUMOR CELLS AND VASCULAR ENDOTHELLUM, AND ITS EFFECTS ON METASTASIS89
The Synthesis of Butyric and Caproic Acids from Ethanol and Acetic Acid by Clostridium Kluyveri89
Isolation and structure of an arrestin gene from Drosophila.89
Host−guest complexation-mediated codelivery of anticancer drug and photosensitizer for cancer photochemotherapy89
Control of seed dormancy in Arabidopsis by a cis -acting noncoding antisense transcript89
A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells89
Productivity, prominence, and the effects of academic environment89
Heteroduplex mobility assay-guided sequence discovery: Elucidation of the small subunit (18S) rDNA sequences of Pfiesteria piscicida and related dinoflagellates from com89
Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways89
The crystal structure of anthranilate synthase from Sulfolobus solfataricus : Functional implications89
Movement dynamics of divisome proteins and PBP2x:FtsW in cells of Streptococcus pneumoniae89
Determination of the aggregate size in detergent solution of the light-harvesting chlorophyll a/b-protein complex from chloroplast membranes89
Firefly “femmes fatales” acquire defensive steroids (lucibufagins) from their firefly prey89
The Stark effect in reaction centers from Rhodobacter sphaeroides R-26 and Rhodopseudomonas viridis.89
Construction and characterization of genomic libraries from specific human chromosomes.89
Isolation of cytokinins from Corynebacterium fascians.89
Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics89
Selective Na V 1.1 activation rescues Dravet syndrome mice from seizures and premature death89
Ecomorphological diversification in squamates from conserved pattern of cranial integration89
Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation89
In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML.89
Properties of the thalamic projection from the posterior medial nucleus to primary and secondary somatosensory cortices in the mouse89
Solution structure of a de novo protein from a designed combinatorial library89
Pathogen escape from host immunity by a genome program for antigenic variation89
Surfactants from the gas phase may promote cloud droplet formation89
Reconstitution of an Escherichia coli repair endonuclease activity from the separated uvrA+ and uvrB+/uvrC+ gene products.89
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences89
The criminogenic and psychological effects of police stops on adolescent black and Latino boys89
The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis89
Sparsity enables estimation of both subcortical and cortical activity from MEG and EEG89
Trogocytosis of peptide–MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils88
Structure of a PE–PPE–EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion88
Iron superoxide dismutase from Escherichia coli at 3.1-A resolution: a structure unlike that of copper/zinc protein at both monomer and dimer levels.88
Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice88
CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock88
Repression of unconscious information by conscious processing: Evidence from affective blindsight induced by transcranial magnetic stimulation88
A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway.88
Gene encoding the sigma 37 species of RNA polymerase sigma factor from Bacillus subtilis.88
Light-harvesting II (B800-B850 complex) structural genes from Rhodopseudomonas capsulata88
Isolation of adenovirus-associated viruses from man.88
Generation of genetically modified rats from embryonic stem cells88
Development of an autonomous and bifunctional quorum-sensing circuit for metabolic flux control in engineered Escherichia coli88
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain88
An ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductases.88
Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment88
Protection of rhesus monkeys from fatal Lassa fever by vaccination with a recombinant vaccinia virus containing the Lassa virus glycoprotein gene.88
A subtilisin-like protein from soybean contains an embedded, cryptic signal that activates defense-related genes88
Defective γ-aminobutyric acid type B receptor-activated inwardly rectifying K + currents in cerebellar granule cells isolated from weaver 88
Contribution of transient receptor potential channels to the control of GABA release from dendrites88
Expression cloning of a CMP-NeuAc:NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1'Cer alpha 2,8-sialyltransferase (GD3 synthase) from human melanoma cells.88
Competition between recombination and epistasis can cause a transition from allele to genotype selection88
Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors88
Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt88
Modulation by neurotransmitters of catecholamine secretion from sympathetic ganglion neurons detected by amperometry88
Oceanic protection of prebiotic organic compounds from UV radiation88
β-Cyclocitral is a conserved root growth regulator88
The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning88
Cooling requirements fueled the collapse of a desert bird community from climate change88
Chemoresponsive alternating supramolecular copolymers created from heterocomplementary calix[4]pyrroles88
From cyclohydrolase to oxidoreductase: Discovery of nitrile reductase activity in a common fold88
Cancer cells induce interleukin-22 production from memory CD4 + T cells via interleukin-1 to promote tumor growth88
High recovery of nitrogenase activity and of 55 Fe-labeled nitrogenase in heterocysts isolated from Anabaena variabilis88
Near-term deployment of carbon capture and sequestration from biorefineries in the United States88
Localized maternal mRNA related to transforming growth factor beta mRNA is concentrated in a cytokeratin-enriched fraction from Xenopus oocytes.88
Dated co-occurrence of Homo erectus and Gigantopithecus from Tham Khuyen Cave, Vietnam.88
Contact-ID, a tool for profiling organelle contact sites, reveals regulatory proteins of mitochondrial-associated membrane formation88
Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria.88
Particularism and the retreat from theory in the archaeology of agricultural origins88
Biosynthesis and assembly of the proton-translocating adenosine triphosphatase complex from chloroplasts88
Nitrate reductase from squash: cDNA cloning and nitrate regulation88
Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest88
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line88
EIN2 mediates direct regulation of histone acetylation in the ethylene response88
Isolation of the Escherichia coli leader peptidase gene and effects of leader peptidase overproduction in vivo.88
Factor XI (plasma thromboplastin antecedent) deficiency in Ashkenazi Jews is a bleeding disorder that can result from three types of point mutations.88
A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution88
0.15263819694519