Proceedings of the National Academy of Sciences of the United States o

Article	Citations
Functional near-infrared spectroscopy reveals brain activity on the move	899
Polymorphic transposable elements contribute to variation in recombination landscapes	583
In This Issue	475
How membrane receptors tread the fine balance between symbiosis and immunity signaling	410
Untangling the CD4 T cell response to the microbiota	394
Photovoltaic effect by soft phonon excitation	393
Engineered CaM2 modulates nuclear calcium oscillation and enhances legume root nodule symbiosis	389
Graphene nanoripples enable unexpected catalytic reactivity	380
How defective mitochondrial electrical activity leads to inherited blindness	360
A law of data separation in deep learning	356
Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability	346
Water striders are impervious to raindrop collision forces and submerged by collapsing craters	341
Pressure pushes tRNA Lys3 into excited conformational states	328
Strong connectivity in real directed networks	321
Human ERG oncoprotein represses a Drosophila LIM domain binding protein–coding gene Chip	292
Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries	285
Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7	281
The COVID-19 pandemic adds another 200,000 deaths (50%) to the annual toll of excess mortality in the United States	273
Modeling for COVID-19 college reopening decisions: Cornell, a case study	271
Social mindfulness for global environmental sustainability?	263
Spiritual over physical formidability determines willingness to fight and sacrifice through loyalty in cross-cultural populations	262
Involvement of Scratch2 in GalR1-mediated depression-like behaviors in the rat ventral periaqueductal gray	256
A bipartite interaction with the processivity clamp potentiates Pol IV-mediated TLS	254
Weakening AMOC reduces ocean carbon uptake and increases the social cost of carbon	246
Vulnerability to natural disasters and sustainable consumption: Unraveling political and regional differences	242

Climate warming drives population trajectories of freshwater fish	235
Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB	229
Reversal of an existing hearing loss by gene activation in Spns2 mutant mice	228
Targeting spike glycans to inhibit SARS-CoV2 viral entry	225
Correction for Andreasson et al., Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular switches	218
Correction for Li et al., SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes	218
Engineered bacteria that self-assemble bioglass polysilicate coatings display enhanced light focusing	218
Correction to Gaffney et al., Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein	213
Correction for Wang et al., Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity	211
Correction for Shanmugapriya et al., Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170	210
Correction to Supporting Information for Ahuja et al., Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease	209
Correction for Dar et al., Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma	207
An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis	203
Touching the classical scaling in penetrative convection	199
Lateral olivocochlear neurons modulate cochlear responses to noise exposure	198
Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic	198
Empowering genome-wide association studies via a visualizable test based on the regional association score	196
Molecular patterns of matrix protein 1 (M1): A strong predictor of adaptive evolution in H9N2 avian influenza viruses	194
Correction for Ahituv et al., Starch-rich plant foods 780,000 y ago: Evidence from Acheulian percussive stone tools	193
Structural stability and thermodynamics of artistic composition	190
Greener skies? The quest for sustainable flying	190
The James Webb Space Telescope prompts a rethink of how galaxies form	189
Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52	188
Kids adopt different ways of coping in wake of the pandemic	187
The evidence remains clear: SARS-CoV-2 emerged via the wildlife trade	187
Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia	186
Photoreduction of mercuric bromides in polar ice	184
Cas9-mediated gene-editing frequency in microalgae is doubled by harnessing the interaction between importin α and phytopathogenic NLSs	182
TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice	181
Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness	180
The decade-long growth of government-authored news media in China under Xi Jinping	179
Fluorescence detection of dopamine signaling to the primate striatum in relation to stimulus–reward associations	179
Extremal structures with embedded prefailure indicators	178
Retraction for Li et al., Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells	177
The origin of color categories	176
In This Issue	175
Slower swimming promotes chemotactic encounters between bacteria and small phytoplankton	174
Modeling DNA methyltransferase function to predict epigenetic correlation patterns in healthy and cancer cells	172
Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae	169
Correction for Magesh et al., Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species	168
Circadian clock control of interactions between eIF2α kinase CPC-3 and GCN1 with ribosomes regulates rhythmic translation initiation	164
Synergetic collision and space separation in microfluidic chip for efficient affinity-discriminated molecular selection	163
Quantifying the impact of air pollution from coal-fired electricity generation on crop productivity in India	163
National religiosity eases the psychological burden of poverty	162
Protein dynamics underlies strong temperature dependence of heat receptors	160
Correction to Supporting Information for Ikeda et al., Seesaw protein: Design of a protein that adopts interconvertible alternative functional conformations and its dynamics	160
Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling	159
Gap junction–transported cAMP from the niche controls stem cell progeny differentiation	159
Tsg101 mimicry of canonical E2 enzymes underlies its role in ubiquitin signaling	156
In This Issue	153

Phage-encoded ten-eleven translocation dioxygenase (TET) is active in C5-cytosine hypermodification in DNA	152
Breaking the mobility–stability dichotomy in organic semiconductors through adaptive surface doping	152
High-impact rare genetic variants in severe schizophrenia	152
Depressive symptoms during the transition to adolescence: Left hippocampal volume as a marker of social context sensitivity	149
Functional redundancy in the toxic pathway of Bt protein Cry1Ab, but not Cry1Fa, against the Asian corn borer	148
Integrative spatiotemporal modeling of biomolecular processes: Application to the assembly of the nuclear pore complex	148
Early life stress is associated with earlier emergence of permanent molars	147
Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast	147
Accounting for spatial sampling patterns in Bayesian phylogeography	146
PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice	146
Maple samaras recover autorotation following raindrop collisions	146
Coherent detection of hidden spin–lattice coupling in a van der Waals antiferromagnet	146
Assembly-enhanced recognition: A biomimetic pathway to achieve ultrahigh affinities	145
Diverse roles of pontine NPS-expressing neurons in sleep regulation	144
Are Americans less likely to reply to emails from Black people relative to White people?	144
Aberrant neuronal hyperactivation causes an age-dependent behavioral decline in Caenorhabditis elegans	143
Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling	143
Tungsten is utilized for lactate consumption and SCFA production by a dominant human gut microbe Eubacterium limosum	143
Tetrapod species–area relationships across the Cretaceous–Paleogene mass extinction	141
Late Cretaceous community structure changed before the asteroid	141
Facile self-assembly of colloidal diamond from tetrahedral patchy particles via ring selection	140
The making of an AI news anchor—and its implications	139
Thermodynamic consistency of autocatalytic cycles	138
Accurate identification and mechanistic evaluation of pathogenic missense variants with Rhapsody-2	138
Early life lead exposure from private well water increases juvenile delinquency risk among US teens	137
Architecture-driven quantitative nanoscopy maps cytoskeleton remodeling	137
Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells	137
Symmetric activation and modulation of the human calcium-sensing receptor	136
Dual-rail encoding with superconducting cavities	135
Differential elimination of marked sex chromosomes enables production of nontransgenic male mosquitoes in a single strain	134
Healthy sleep durations appear to vary across cultures	134
Directional water navigation and reallocation in Tillandsia capitata	134
Observation of the most H 2 -dense filled ice under high pressure	134
Trojan horse peptide conjugates remodel the activity spectrum of clinical antibiotics	134
Simple, fast, and flexible framework for matrix completion with infinite width neural networks	134
Contraception ends the genetic maintenance of human same-sex sexual behavior	133
Cell–cell contact landscapes in Xenopus gastrula tissues	133
State-dependent motion of a genetically encoded fluorescent biosensor	133
Phylogenomics of the tetraploid Hawaiian lobeliads: Implications for their origin, dispersal history, and adaptive radiation	131
Genomic adaptations for arboreal locomotion in Asian flying treefrogs	130
Methodological and conceptual considerations of the TCM evolution	130
Nucleocytoplasmic trafficking and turnover mechanisms of BRASSINAZOLE RESISTANT1 in Arabidopsis thaliana	129
Functional alterations in cortical processing of speech in glioma-infiltrated cortex	129
Phase separation in mitochondrial fate and mitochondrial diseases	129
Explaining happiness trends in Europe	127
Long-term employment and health effects of active labor market programs	127
Measuring long-term exposure to wildfire PM 2.5 in California: Time-varying inequities in environmental burden	127
Designing the stripe-ordered cuprate phase diagram through uniaxial-stress	127
Redox conditions correlated with vibronic coupling modulate quantum beats in photosynthetic pigment–protein complexes	126
Mercury’s complex legacy	126
N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells	125
β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells	124
The gender gap in the ownership of promising land	124
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells	124
Ciliary localization of a light-activated neuronal GPCR shapes behavior	124
Inversion of pop-out for a distracting feature dimension in monkey visual cortex	123
Antiprion systems in yeast cooperate to cure or prevent the generation of nearly all [ PSI + ] and [URE3] prions	123
Individuals benefit individual out-group members rather than harm in-group members	123
Topography affects not only interhemispheric asymmetry of westerly winds and thus storminess but also ocean circulation	123
Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders	122
Persistent deep water anoxia in the eastern South Atlantic during the last ice age	122
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses	121
The quorum-sensing peptidic inhibitor rescues host immune system eradication: A novel infectivity mechanism	121
Crosslinguistic word order variation reflects evolutionary pressures of dependency and information locality	121
Functional genomics analysis reveals the evolutionary adaptation and demographic history of pygmy lorises	120
On peer review—then, now, and soon to be?	120
The importance of elders: Extending Hamilton’s force of selection to include intergenerational transfers	119
Conserving rhinoceros in the face of disease	119
In vitro investigation of protein assembly by combined microscopy and infrared spectroscopy at the nanometer scale	119
Hydrodynamic flow and concentration gradients in the gut enhance neutral bacterial diversity	119
Gluing blood into gel by electrostatic interaction using a water-soluble polymer as an embolic agent	119
Cytosolic and mitochondrial ribosomal proteins mediate the locust phase transition via divergence of translational profiles	117
Low-cost solar power enables a sustainable energy industry system	117
The importance of geography in forecasting future fire patterns under climate change	117
Distinct neural networks derived from galanin-containing nociceptors and neurotensin-expressing pruriceptors	117
Simulating COVID-19 classroom transmission on a university campus	117
A forward modeling approach to analyzing galaxy clustering with S im BIG	117
Minority salience and the overestimation of individuals from minority groups in perception and memory	117
The dual-process theory of moral judgment does not deny that people can make compromise judgments	117
How can we reform the STEM tenure system for the 21st Century?	116

CoRa—A general approach for quantifying biological feedback control	116
Chemometrics and genome mining reveal an unprecedented family of sugar acid–containing fungal nonribosomal cyclodepsipeptides	116
Self-consistent dispersal puts tight constraints on the spatiotemporal organization of species-rich metacommunities	116
Wandering mastodons reveal the complexity of Ice Age extinctions	115
Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance	115
Slope classicality in higher Coleman theory via highest weight vectors in completed cohomology	115
High-throughput measurement of elastic moduli of microfibers by rope coiling	115
Promoting C–F bond activation via proton donor for CF 4 decomposition	114
Tumor-polarized GPX3 + AT2 lung epithelial cells promote premetastatic niche formation	114
Using neuroimaging genomics to investigate the evolution of human brain structure	114
Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2	113
Clocking out and letting go to unleash green biotech applications in a photosynthetic host	113
Investigating 3D microbial community dynamics of the rhizosphere using quantitative phase and fluorescence microscopy	112
Identification of KU-55933 as an anti-atherosclerosis compound by using a hemodynamic-based high-throughput drug screening platform	112
Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease	112
Emotional (in)stability: Neuroticism is associated with increased variability in negative emotion after all	112
Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage	112
Impression management in research reporting: When effects are not really as pronounced as claimed	111
Modeling the population-level impact of a third dose of MMR vaccine on a mumps outbreak at the University of Iowa	111
Hidden in plain sight: (Re)definition of a key lepidopteran color patterning gene	111
Probing both sides of the story	111
Sm complex assembly and 5′ cap trimethylation promote selective processing of snRNAs by the 3′ exonuclease TOE1	111
Membrane association of active genes organizes the chloroplast nucleoid structure	110
Breaking the symmetry of cell contractility drives tubulogenesis via CXCL1 polarization	110
Nutrient-derived signals regulate eosinophil adaptation to the small intestine	109
A randomized trial of behavioral interventions yielding sustained reductions in distracted driving	109
Thermo-photo catalytic anode process for carbonate-superstructured solid fuel cells	109
Rapid shear zone weakening during subduction initiation	109
Sound-mediated nucleation and growth of amyloid fibrils	108
Photodissociation of dicarbon: How nature breaks an unusual multiple bond	108
Structure-based investigation of a DNA aptamer targeting PTK7 reveals an intricate 3D fold guiding functional optimization	108
Arabidopsis protein S -acyl transferases positively mediate BR signaling through S -acylation of BSK1	108
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+ -activated large-conductance K + channels and motor coordination	107
Genome-wide detection of human variants that disrupt intronic branchpoints	107
Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification	107
On zombies, struldbrugs, and other horrors of the scientific literature	107
Pinning down a perpetrator in postsurgical eye pain	106
Propulsive cell entry diverts pathogens from immune degradation by remodeling the phagocytic synapse	106
Pathways to parasitic strategies in ants	106
Data-driven classification of ligand unbinding pathways	106
Modeling blood metabolite homeostatic levels reduces sample heterogeneity across cohorts	105
Ancient Maya reservoirs, constructed wetlands, and future water needs	105
Parameters of clustered suboptimal miRNA biogenesis	104
Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance	104
Glucuronic acid confers colonization advantage to enteric pathogens	104
NOTUM-mediated WNT silencing drives extravillous trophoblast cell lineage development	104
Oligopoly competition between satellite constellations will reduce economic welfare from orbit use	104
Reply to Kodner et al.: Fundamental misunderstanding of both model and methods	104
Observing heroic behavior and its influencing factors in immersive virtual environments	104
Exploring the associations between discrimination, coping, skin tone, and the psychosocial health of young adults of color	104
Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology	102
Balance and imbalance in biogeochemical cycles reflect the operation of closed, exchange, and open sets	102
IL-1 receptor antagonism reveals a yin-yang relationship between NFκB and interferon signaling in chronic lymphocytic leukemia	102
Phylogenetic evidence clarifies the history of the extrusion of Indochina	101
Band gap opening of metallic single-walled carbon nanotubes via noncovalent symmetry breaking	101
A sodium-dependent trehalose transporter contributes to anhydrobiosis in insect cell line, Pv11	100
Endurance athletes hiding in plain sight in the high Andes	100
Thermoelectricity, metallic liquidity, and magnetohydrodynamics	99
Atomic resolution structure of full-length human insulin fibrils	99
Modulating metal-centered dimerization of a lanthanide chaperone protein for separation of light lanthanides	99
Deep silicification–assisted long-term preservation of structural and genomic information across biospecies: From micro to macro	99
Harnessing quantum light for microscopic biomechanical imaging of cells and tissues	99
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson’s disease	99
Integrating life history and behavioral aging in the wild	98
Thirty-five years later: Long-term effects of the Matlab maternal and child health/family planning program on older women’s well-being	98
Multiscale modeling shows how 2’-deoxy-ATP rescues ventricular function in heart failure	97
Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels	97
RNA m 6 A demethylase ALKBH5 regulates the development of γδ T cells	97
Adaptive cooling strategy via human hair: High optothermal conversion efficiency of solar radiation into thermal dissipation	97
Atmospheric variability contributes to increasing wildfire weather but not as much as global warming	97
Middle Pleistocene fire use: The first signal of widespread cultural diffusion in human evolution	96
Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na v 1.5	96
Estimating genetic nurture with summary statistics of multigenerational genome-wide association studies	95
Cytoplasmic stirring by active carpets	95
Two-pore channels regulate endomembrane tension to enable remodeling and resolution of phagolysosomes	95
Transcranial magnetic stimulation to frontal but not occipital cortex disrupts endogenous attention	95
Simulating institutional heterogeneity in sustainability science	95
High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma	94
Theory and observations of the interaction between magnetohydrodynamic waves and shocks	94
Orc6 is a component of the replication fork and enables efficient mismatch repair	94
Biodiversity mitigates drought effects in the decomposer system across biomes	93
Thermodynamic feasibility of shipboard conversion of marine plastics to blue diesel for self-powered ocean cleanup	93
Cell–matrix feedback controls stretch-induced cellular memory and fibroblast activation	93
A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation	92
Strategy to develop broadly effective multivalent COVID-19 vaccines against emerging variants based on Ad5/35 platform	92
TGM2-mediated histone transglutamination is dictated by steric accessibility	91
Multiple dimeric structures and strand-swap dimerization of E-cadherin in solution visualized by high-speed atomic force microscopy	91
Dual membrane-spanning anti-sigma factors regulate vesiculation in Bacteroides thetaiotaomicron	91
A heritable iron memory enables decision-making in Escherichia coli	91
Higher-order effects, continuous species interactions, and trait evolution shape microbial spatial dynamics	90
From the laboratory to the consumer: Innovation, supply chain, and adoption with applications to natural resources	90
Emergent time scales of epistasis in protein evolution	90
The global succinylation of SARS-CoV-2–infected host cells reveals drug targets	90
Identification of two archaeal GDGT lipid–modifying proteins reveals diverse microbes capable of GMGT biosynthesis and modification	89
Predictive phage therapy for Escherichia coli urinary tract infections: Cocktail selection for therapy based on machine learning models	89