Proceedings of the National Academy of Sciences of the United States o

Article	Citations
Natural disasters as natural experiments: Lessons for human stress science	1492
Coming full circle on diazotrophy in the marine cyanobacterium Trichodesmium	1109
Breaking the symmetry of cell contractility drives tubulogenesis via CXCL1 polarization	847
In This Issue	810
In situ formed depot of elastin-like polypeptide-hirudin fusion protein for long-acting antithrombotic therapy	748
The complexity of aerosol production from bubble bursting	722
Trimethylamine-N-oxide depletes urea in a peptide solvation shell	484
Intimate contact between red blood cells and vessel walls is sufficient to stabilize capillary networks during development	463
Bayesian estimation of SARS-CoV-2 prevalence in Indiana by random testing	448
Reconstitution of a biofilm adhesin system from a sulfate-reducing bacterium in Pseudomonas fluorescens	414
March of the proviruses	402
Michael Oldstone (1932–2023): Pioneer in viral pathogenesis, historian and author	393
Atomic resolution structure of full-length human insulin fibrils	391
PVDF–HFP@Nafion-based quasisolid polymer electrolyte for high migration number in working rechargeable Na–O 2 batteries	375
In vivo selection of synthetic nucleocapsids for tissue targeting	336
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation	327
N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells	324
A method to predict the response to directional selection using a Kalman filter	324
Microbial self-recycling and biospherics	323
Interventions can shift the thermal optimum for parasitic disease transmission	315
Membrane association of active genes organizes the chloroplast nucleoid structure	309
Bcl6 , Irf2 , and Notch2 promote nonclassical monocyte development	309
Multistability of segmented rings by programming natural curvature	303
Exotic self-assembly of hard spheres in a morphometric solvent	292
The ecological and geographic dynamics of extinction: Niche modeling and ecological marginalization	290

VLM catecholaminergic neurons control tumor growth by regulating CD8 + T cells	284
Awareness and use of (emergency) sick leave: US employees’ unaddressed sick leave needs in a global pandemic	282
Immature HIV-1 assembles from Gag dimers leaving partial hexamers at lattice edges as potential substrates for proteolytic maturation	279
Allow Golden Rice to save lives	275
Scaling of Berry-curvature monopole dominated large linear positive magnetoresistance	267
Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling	251
Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts	249
Reply to Kodner et al.: Fundamental misunderstanding of both model and methods	244
Plant organellar genomes utilize gene conversion to drive heteroplasmic sorting	243
Cell reprogramming design by transfer learning of functional transcriptional networks	240
Effects of double-dose algebra on college persistence and degree attainment	239
In This Issue	231
Magnetoelastic standing waves induced in UO 2 by microsecond magnetic field pulses	231
In This Issue	231
In This Issue	228
In This Issue	222
Supergenes, supergenomes, and complex social traits	219
Life 2.0—A CRISPR path to a sustainable planet	219
Adult specifier E93 takes control of reproductive cyclicity in mosquitoes	219
QnAs with Kenneth W. Kinzler	217
Watt W. Webb: His measurements of the seemingly inaccessible broadened the horizons of biophysics	216
Pathways to parasitic strategies in ants	214
In high school math, more instructional time helps, but the tracking dilemma remains	210
Shining light on photosynthetic microbes and manganese-enriched rock varnish	208
Frontrunning the signals: As arbitrage between sophisticates	205
Why zebra finches don’t get hypercholesterolemia	201
Genomics serology to inform therapies and vaccines for arthritogenic alphaviruses	201
23 Na imaging: Worth its salt for understanding multiple sclerosis	200
QnAs with Hugo J. Bellen	200
Reply to McGrew: Chimpanzees do not exhibit widespread cultural diffusion	200
Casein kinase rolls the dice in clocks from bread mold to humans	191
QnAs with David Van Essen	191
A tribute to Eddy Fischer (April 6, 1920–August 27, 2021): Passionate biochemist and mentor	191
Linking a nuclear lncRNA to cytoplasmic lysosome integrity and cell death	190
Reply to Zhang and Xu: Environment is indeed important in any phenotypic study	189
In This Issue	189
Perfect Match Genomic Landscape strategy: Refinement and customization of reference genomes	186
Reply to Best and Ashby: The concept of evolutionarily stable strategies (ESS) helps link ecology and evolution	186
Biochemical cartilage changes based on MRI-defined T2 relaxation times do not equal OA detection	186
Rapid emergence of virus–host mutualism under stress	181
Reply to Marot et al.: The struggle to comply with social-distancing is multifaceted, as are the ways of mitigating it	180
To eat, or not to eat, that is the question: Neural stem cells escape phagocytosis in autism with macrocephaly	177
An organic transistor matrix for multipoint intracellular action potential recording	173
Multilevel transcrustal magmatic system beneath the Geysers-Clear Lake area	173
Can feeding the gut microbiome treat malnutrition?	173
NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells	172
MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate	172
Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo	172
Scaling and spontaneous symmetry restoring of topological defect dynamics in liquid crystal	171
Hippocampal ripples signal contextually mediated episodic recall	170

Early life lead exposure from private well water increases juvenile delinquency risk among US teens	170
Plants sum and subtract stimuli over different timescales	170
Transition metal dichalcogenide nanospheres for high-refractive-index nanophotonics and biomedical theranostics	169
Suppressing transverse mode instability through multimode excitation in a fiber amplifier	169
A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family	169
Performance enhancement and mechanism of electroenhanced peroxymonosulfate activation by single-atom Fe catalyst modified electrodes	167
The extent of soil loss across the US Corn Belt	167
Presaccadic preview shapes postsaccadic processing more where perception is poor	167
On the surprising effectiveness of a simple matrix exponential derivative approximation, with application to global SARS-CoV-2	165
Two-dimensional fractal nanocrystals templating for substantial performance enhancement of polyamide nanofiltration membrane	164
Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM	164
Clock proteins and training modify exercise capacity in a daytime-dependent manner	162
Evidence for an emergent anomalous metallic state in compressed titanium	160
Human cytomegalovirus lytic infection inhibits replication-dependent histone synthesis and requires stem loop binding protein function	160
Quenching of zonal winds in Jupiter’s interior	159
An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis	159
Capillary regression leads to sustained local hypoperfusion by inducing constriction of upstream transitional vessels	159
Learning through the grapevine and the impact of the breadth and depth of social networks	158
MBD2a–NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression	157
Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis	156
Water striders are impervious to raindrop collision forces and submerged by collapsing craters	155
Babbling opens the sensory phase for imitative vocal learning	155
Historical Southern Hemisphere biomass burning variability inferred from ice core carbon monoxide records	154
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia	154
Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA	154
ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis	154
Genomic adaptations for arboreal locomotion in Asian flying treefrogs	154
Ride-hailing technology mitigates effects of driver racial discrimination, but effects of residential segregation persist	153
Multiple dimeric structures and strand-swap dimerization of E-cadherin in solution visualized by high-speed atomic force microscopy	153
Restoration of atypical protein kinase C ζ function in autosomal dominant polycystic kidney disease ameliorates disease progression	153
Motor learning without movement	152
In This Issue	152
Tradeoffs for a viral mutant with enhanced replication speed	150
Chemical mapping of the surface interactome of PIEZO1 identifies CADM1 as a modulator of channel inactivation	149
Mixed equilibrium/nonequilibrium effects govern surface mobility in polymer glasses	148
Topology, dynamics, and control of a muscle-architected soft arm	147
Shedding light with harmonic radar: Unveiling the hidden impacts of streetlights on moth flight behavior	147
Two intrinsic timing mechanisms set start and end times for dendritic arborization of a nociceptive neuron	147
Expression attenuation as a mechanism of robustness against gene duplication	146
Precise initial abundance of Niobium-92 in the Solar System and implications for p -process nucleosynthesis	146
Dominance of felsic continental crust on Earth after 3 billion years ago is recorded by vanadium isotopes	145
Heterogeneous Hadean crust with ambient mantle affinity recorded in detrital zircons of the Green Sandstone Bed, South Africa	145
TapA acts as specific chaperone in TasA filament formation by strand complementation	144
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell	143
Oceanic nutrient rise and the late Miocene inception of Pacific oxygen-deficient zones	143
Chemical factors induce aggregative multicellularity in a close unicellular relative of animals	142
Human oral lectin ZG16B acts as a cell wall polysaccharide probe to decode host–microbe interactions with oral commensals	142
Hematopoietic Jagged1 is a fetal liver niche factor required for functional maturation and engraftment of fetal hematopoietic stem cells	140
Characteristics and anatomic location of PD-1 + TCF1 + stem-like CD8 T cells in chronic viral infection and cancer	140
Probing the psychology of AI models	138
The reconstructed cranium of Pierolapithecus and the evolution of the great ape face	138
A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane	138
Vibrational relaxation dynamics in layered perovskite quantum wells	137
A high-resolution record of early Paleozoic climate	135
The origin of volatile elements in the Earth–Moon system	135
Reciprocal regulation of IL-33 receptor–mediated inflammatory response and pulmonary fibrosis by TRAF6 and USP38	133
Assessing the roles of nitrogen, biomass, and niche dimensionality as drivers of species loss in grassland communities	132
Insights into bear evolution from a Pleistocene polar bear genome	132
High exposure of global tree diversity to human pressure	132
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor	131
Specialization of the photoreceptor transcriptome by Srrm3 -dependent microexons is required for outer segment maintenance and vision	131
Calcium channel blockers potentiate gemcitabine chemotherapy  in pancreatic cancer	131
Stochastic microbiome assembly depends on context	129
Genetic removal of p70 S6K1 corrects coding sequence length-dependent alterations in mRNA translation in fragile X syndrome mice	129
Protein structure–based gene expression signatures	128
Deep learning identifies synergistic drug combinations for treating COVID-19	127
Bioinspired micro/nanomotor with visible light energy–dependent forward, reverse, reciprocating, and spinning schooling motion	127
Defective myelination in an RNA polymerase III mutant leukodystrophic mouse	127
Magmatic thickening of crust in non–plate tectonic settings initiated the subaerial rise of Earth’s first continents 3.3 to 3.2 billion years ago	126
Hydrodynamic flow and concentration gradients in the gut enhance neutral bacterial diversity	126
Genomic and transcriptomic analyses of the subterranean termite Reticulitermes speratus : Gene duplication facilitates social evolution	126
The intracellular Ca2+channel TRPML3 is a PI3P effector that regulates autophagosome biogenesis	125
Trait-based filtering mediates the effects of realistic biodiversity losses on ecosystem functioning	125
Assisted assembly of bacteriophage T7 core components for genome translocation across the bacterial envelope	125
Isotope mass-balance constraints preclude that mafic weathering drove Neogene cooling	124
Middle Pleistocene fire use: The first signal of widespread cultural diffusion in human evolution	124
Intracellular infection by symbiotic bacteria requires the mitotic kinase AURORA1	124
A large-scale study of stress, emotions, and blood pressure in daily life using a digital platform	124
Loss of resilience preceded transformations of pre-Hispanic Pueblo societies	123
Inducible CRISPR-targeted “knockdown” of human gut Bacteroides in gnotobiotic mice discloses glycan utilization strategies	122

Adaptive DNA amplification of synthetic gene circuit opens a way to overcome cancer chemoresistance	122
Toward vanishing droplet friction on repellent surfaces	121
The Titanic question in TB control: Should we worry about the bummock?	121
Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors	120
Measuring the subcellular compartmentalization of viral infections by protein complementation assay	120
Blockade of the protease ADAM17 ameliorates experimental pancreatitis	120
Opinion: To save whales, look to the sky	119
In This Issue	118
The superior explanatory power of models that admit trade-offs in moral judgment and decision-making	118
Pivotal voting: The opportunity to tip group decisions skews juries and other voting outcomes	118
Henry Bourne: G protein wizard, academic innovator, commentator, and critic	118
An insulator that regulates chromatin extrusion and class switch recombination	118
Elastic turbulence drives particle crystallization	118
Intratumoral injection of schwannoma with attenuated Salmonella typhimurium induces antitumor immunity and controls tumor growth	117
Architectural experience influences the processing of others’ body expressions	117
The new W family reconstructs the evolution of MHC genes	117
Human casualties are the dominant cost of human–wildlife conflict in India	117
Evolutionary history of MEK1 illuminates the nature of deleterious mutations	117
Why ex post peer review encourages high-risk research while ex ante review discourages it	117
In This Issue	117
Molecular mechanisms underlying metamorphosis in the most-ancestral winged insect	117
Validity of forensic cartridge-case comparisons	116
Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen–targeted therapies	116
Endothelial peroxiredoxin-4 is indispensable for blood–brain barrier integrity and long-term functional recovery after ischemic stroke	116
Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms	115
Protein and lipid mass concentration measurement in tissues by stimulated Raman scattering microscopy	115
Continuous variable responses and signal gating form kinetic bases for pulsatile insulin signaling and emergence of resistance	114
Crosslinguistic word order variation reflects evolutionary pressures of dependency and information locality	114
Enhancement of the anomalous Hall effect by distorting the Kagome lattice in an antiferromagnetic material	114
The neocortical infrastructure for language involves region-specific patterns of laminar gene expression	113
Membrane nanotubes transform into double-membrane sheets at condensate droplets	113
Convergence in hearing-related genes between echolocating birds and mammals	113
Acquisition of optimal TFH cell function is defined by specific molecular, positional, and TCR dynamic signatures	112
Leveraging artificial intelligence to improve people’s planning strategies	112
Loss of Ca V 1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory	112
A nitrogen isotopic shift in fish otolith–bound organic matter during the Late Cretaceous	112
Diel transcriptional oscillations of light-sensitive regulatory elements in open-ocean eukaryotic plankton communities	112
Host’s guardian protein counters degenerative symbiont evolution	111
The secretome mouse provides a genetic platform to delineate tissue-specific in vivo secretion	111
Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation	111
A proposed unified mitotic chromosome architecture	110
A quantitative and spatial analysis of cell cycle regulators during the fission yeast cycle	110
Reversible dougong structured receptor–ligand recognition for building dynamic extracellular matrix mimics	109
Photovoltaic-driven microbial protein production can use land and sunlight more efficiently than conventional crops	109
A genetically encoded photoproximity labeling approach for mapping protein territories	109
Rise ofRuppiain Chesapeake Bay: Climate change–driven turnover of foundation species creates new threats and management opportunities	109
Dynamically structured bubbling in vibrated gas-fluidized granular materials	109
An aggregation inhibitor specific to oligomeric intermediates of Aβ42 derived from phage display libraries of stable, small proteins	108
Two superconducting states with broken time-reversal symmetry in FeSe 1− x S x	108
Somatostatin regulates central clock function and circadian responses to light	108
Wildland-urban fire disasters aren’t actually a wildfire problem	108
STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice	108
Osteoblast-lineage calcium/calmodulin-dependent kinase 2 delta and gamma regulates bone mass and quality	108
Redox conditions correlated with vibronic coupling modulate quantum beats in photosynthetic pigment–protein complexes	107
El Niño-Southern Oscillation forcing on carbon and water cycling in a Bornean tropical rainforest	107
Reply to Harwood et al.: Alternative functional conformations of native human α 2 -macroglobulin	106
Voyager still breaking barriers decades after launch	106
Reply to Wagman et al.: Data-driven assessments should establish the landscape of what is “within reach” of malaria transmission control	106
Adopting electric school buses in the United States: Health and climate benefits	105
Results from a 2020 field experiment encouraging voting by mail	105
Ion channel selectivity through ion-modulated changes of selectivity filter p K a values	105
Direct-write 3D printing of plasmonic nanohelicoids by circularly polarized light	105
The endoplasmic reticulum adopts two distinct tubule forms	104
Structural and electronic trends of optical cycling centers in polyatomic molecules revealed by microwave spectroscopy of MgCCH, CaCCH, and SrCCH	104
Antarctica as an evolutionary arena during the Cenozoic global cooling	104
Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate	104
In vitro cell cycle oscillations exhibit a robust and hysteretic response to changes in cytoplasmic density	104
Impact of crowding on the diversity of expanding populations	103
Plasma membrane association and resistosome formation of plant helper immune receptors	103
Circuit-specific enteric glia regulate intestinal motor neurocircuits	102
Sharp thresholds limit the benefit of defector avoidance in cooperation on networks	102
Hyperactive Rac stimulates cannibalism of living target cells and enhances CAR-M-mediated cancer cell killing	102
Integrating biogeography and behavioral ecology to rapidly address biodiversity loss	102
Diverse communication strategies in bees as a window into adaptations to an unpredictable world	102
Discordant clinical features of identical hypertrophic cardiomyopathy twins	102
A sub-10-nm, folic acid-conjugated gold nanoparticle as self-therapeutic treatment of tubulointerstitial fibrosis	101
The making of an AI news anchor—and its implications	101
CTLA-4 on thymic epithelial cells complements Aire for T cell central tolerance	101
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals	101
Neural functional theory for inhomogeneous fluids: Fundamentals and applications	101
Shortened tethering filaments stabilize presynaptic vesicles in support of elevated release probability during LTP in rat hippocampus	101
Mutational background influencesP. aeruginosaciprofloxacin resistance evolution but preserves collateral sensitivity robustness	100
CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes	100
Behavioral encoding across timescales by region-specific dopamine dynamics	100
Design and synthesis of a small molecular NIR-II chemiluminescence probe for in vivo - activated H 2 S imaging	99
Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene	99
The iron chaperone and nucleic acid–binding activities of poly(rC)-binding protein 1 are separable and independently essential	99
Single-neuron bursts encode pathological oscillations in subcortical nuclei of patients with Parkinson’s disease and essential tremor	99
Input integration by the circadian clock exhibits nonadditivity and fold-change detection	99
Symmetry and asymmetry in biological structures	99
Voltage- and Ca 2+ -dependent SV/TPC1 ion channel structure at the onset of opening	99
The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily	98
Plastic deformation of superionic water ices	98
Cyanobacteria provide a new paradigm in the regulation of cofactor dependence	98
Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis	98