Proceedings of the National Academy of Sciences of the United States o

Article	Citations
Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance	864
Functional near-infrared spectroscopy reveals brain activity on the move	573
N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells	564
Topography affects not only interhemispheric asymmetry of westerly winds and thus storminess but also ocean circulation	473
The dual-process theory of moral judgment does not deny that people can make compromise judgments	449
Adaptive cooling strategy via human hair: High optothermal conversion efficiency of solar radiation into thermal dissipation	404
Slope classicality in higher Coleman theory via highest weight vectors in completed cohomology	383
Mercury’s complex legacy	379
Individuals benefit individual out-group members rather than harm in-group members	373
How can we reform the STEM tenure system for the 21st Century?	370
Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels	338
Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+breast cancer by ceramide-loaded nanoparticles	335
Gluing blood into gel by electrostatic interaction using a water-soluble polymer as an embolic agent	334
Sound-mediated nucleation and growth of amyloid fibrils	333
Distinct neural networks derived from galanin-containing nociceptors and neurotensin-expressing pruriceptors	314
Polymorphic transposable elements contribute to variation in recombination landscapes	311
In This Issue	294
Reply to Kodner et al.: Fundamental misunderstanding of both model and methods	283
Breaking the symmetry of cell contractility drives tubulogenesis via CXCL1 polarization	275
The quorum-sensing peptidic inhibitor rescues host immune system eradication: A novel infectivity mechanism	272
Memory’s gatekeeper: The role of PFC in the encoding of congruent events	265
IL-1 receptor antagonism reveals a yin-yang relationship between NFκB and interferon signaling in chronic lymphocytic leukemia	262
Cytosolic and mitochondrial ribosomal proteins mediate the locust phase transition via divergence of translational profiles	257
Gadolinium enhancement of cranial nerves: Implications for interstitial fluid drainage from brainstem into cranial nerves in humans	253
Rab3 mediates a pathway for endocytic sorting and plasma membrane recycling of ordered microdomains	247

How membrane receptors tread the fine balance between symbiosis and immunity signaling	245
Identifying regulation with adversarial surrogates	245
Untangling the CD4 T cell response to the microbiota	237
Simple, fast, and flexible framework for matrix completion with infinite width neural networks	236
Genomic adaptations for arboreal locomotion in Asian flying treefrogs	229
Photovoltaic effect by soft phonon excitation	225
Engineered CaM2 modulates nuclear calcium oscillation and enhances legume root nodule symbiosis	222
Graphene nanoripples enable unexpected catalytic reactivity	220
DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8	213
Architecture-driven quantitative nanoscopy maps cytoskeleton remodeling	210
Croquemort elicits activation of the immune deficiency pathway in ticks	208
How defective mitochondrial electrical activity leads to inherited blindness	202
Interacting pest control and pollination services in coffee systems	201
Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability	200
A law of data separation in deep learning	200
Water striders are impervious to raindrop collision forces and submerged by collapsing craters	198
Pressure pushes tRNA Lys3 into excited conformational states	197
Strong connectivity in real directed networks	194
Human ERG oncoprotein represses a Drosophila LIM domain binding protein–coding gene Chip	191
Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries	191
Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis	190
Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7	189
Thermoelectricity, metallic liquidity, and magnetohydrodynamics	188
Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na v 1.5	186
The COVID-19 pandemic adds another 200,000 deaths (50%) to the annual toll of excess mortality in the United States	186
Modeling for COVID-19 college reopening decisions: Cornell, a case study	185
Incentives can spur COVID-19 vaccination uptake	185
The circadian clock ensures successful DNA replication in cyanobacteria	183
Larger images are better remembered during naturalistic encoding	183
The unintended consequences of US immigration enforcement policies	183
Social mindfulness for global environmental sustainability?	181
Spiritual over physical formidability determines willingness to fight and sacrifice through loyalty in cross-cultural populations	180
Involvement of Scratch2 in GalR1-mediated depression-like behaviors in the rat ventral periaqueductal gray	179
The new W family reconstructs the evolution of MHC genes	178
The pathogenic T42A mutation in SHP2 rewires the interaction specificity of its N-terminal regulatory domain	177
Self-consistent dispersal puts tight constraints on the spatiotemporal organization of species-rich metacommunities	176
CoRa—A general approach for quantifying biological feedback control	175
Persistent deep water anoxia in the eastern South Atlantic during the last ice age	174
Pinning down a perpetrator in postsurgical eye pain	173
Designing the stripe-ordered cuprate phase diagram through uniaxial-stress	171
Membrane association of active genes organizes the chloroplast nucleoid structure	170
Exploring the associations between discrimination, coping, skin tone, and the psychosocial health of young adults of color	170
A bipartite interaction with the processivity clamp potentiates Pol IV-mediated TLS	169
Weakening AMOC reduces ocean carbon uptake and increases the social cost of carbon	166
Investigating 3D microbial community dynamics of the rhizosphere using quantitative phase and fluorescence microscopy	165
Vulnerability to natural disasters and sustainable consumption: Unraveling political and regional differences	164
Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology	162
Climate warming drives population trajectories of freshwater fish	159
Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB	159
Impression management in research reporting: When effects are not really as pronounced as claimed	158

Reversal of an existing hearing loss by gene activation in Spns2 mutant mice	158
Targeting spike glycans to inhibit SARS-CoV2 viral entry	157
State-dependent motion of a genetically encoded fluorescent biosensor	155
Magnetic soft microrobots for erectile dysfunction therapy	154
Modeling the population-level impact of a third dose of MMR vaccine on a mumps outbreak at the University of Iowa	154
Insurance and climate risks: Policy lessons from three bounding scenarios	154
Engineered bacteria that self-assemble bioglass polysilicate coatings display enhanced light focusing	152
Correction for Andreasson et al., Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular switches	151
Hidden in plain sight: (Re)definition of a key lepidopteran color patterning gene	149
Consistently estimating network statistics using aggregated relational data	149
Correction for Li et al., SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes	149
Symmetry and asymmetry in biological structures	147
Redox conditions correlated with vibronic coupling modulate quantum beats in photosynthetic pigment–protein complexes	146
The importance of elders: Extending Hamilton’s force of selection to include intergenerational transfers	146
Harnessing quantum light for microscopic biomechanical imaging of cells and tissues	145
Ancient Maya reservoirs, constructed wetlands, and future water needs	144
Challenging the Bayesian confidence hypothesis in perceptual decision-making	144
Correction to Gaffney et al., Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein	144
Correction for Wang et al., Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity	144
Correction to Supporting Information for Ahuja et al., Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease	143
Correction for Shanmugapriya et al., Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170	143
Correction for Dar et al., Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma	142
High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma	142
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+ -activated large-conductance K + channels and motor coordination	140
An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis	140
Estimating genetic nurture with summary statistics of multigenerational genome-wide association studies	139
An IL-23-STAT4 pathway is required for the proinflammatory function of classical dendritic cells during CNS inflammation	139
Touching the classical scaling in penetrative convection	138
Lateral olivocochlear neurons modulate cochlear responses to noise exposure	137
Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state modeling	137
Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic	136
Empowering genome-wide association studies via a visualizable test based on the regional association score	135
Correction for Ahituv et al., Starch-rich plant foods 780,000 y ago: Evidence from Acheulian percussive stone tools	134
Stomatal patchiness and cellular computing	134
Molecular patterns of matrix protein 1 (M1): A strong predictor of adaptive evolution in H9N2 avian influenza viruses	134
Structural stability and thermodynamics of artistic composition	133
Integrating life history and behavioral aging in the wild	132
Greener skies? The quest for sustainable flying	131
Prolonged exertion of self-control causes increased sleep-like frontal brain activity and changes in aggressivity and punishment	130
The making of an AI news anchor—and its implications	130
The James Webb Space Telescope prompts a rethink of how galaxies form	129
Convergent evolution of venom gland transcriptomes across Metazoa	129
Trait-based filtering mediates the effects of realistic biodiversity losses on ecosystem functioning	128
Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52	128
Nutrient-derived signals regulate eosinophil adaptation to the small intestine	128
Multiple dimeric structures and strand-swap dimerization of E-cadherin in solution visualized by high-speed atomic force microscopy	127
Subcellular activation of β-adrenergic receptors using a spatially restricted antagonist	127
The evidence remains clear: SARS-CoV-2 emerged via the wildlife trade	126
PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana	126
Differing biophysical properties underpin the unique signaling potentials within the plant phytochrome photoreceptor families	126
Thirty-five years later: Long-term effects of the Matlab maternal and child health/family planning program on older women’s well-being	126
The ubiquitous microtubule-associated protein 4 (MAP4) controls organelle distribution by regulating the activity of the kinesin motor	125
Higher-order effects, continuous species interactions, and trait evolution shape microbial spatial dynamics	125
High-throughput measurement of elastic moduli of microfibers by rope coiling	124
Kids adopt different ways of coping in wake of the pandemic	124
Rapid shear zone weakening during subduction initiation	124
Multiscale modeling shows how 2’-deoxy-ATP rescues ventricular function in heart failure	124
Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2	123
Clocking out and letting go to unleash green biotech applications in a photosynthetic host	123
Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia	123
Heterogenous biofilm mass-transport model replicates periphery sequestration of antibiotics in Pseudomonas aeruginosa PAO1 microcolonies	122
Modeling blood metabolite homeostatic levels reduces sample heterogeneity across cohorts	122
Cas9-mediated gene-editing frequency in microalgae is doubled by harnessing the interaction between importin α and phytopathogenic NLSs	121
Probing both sides of the story	121
Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness	121
Photoreduction of mercuric bromides in polar ice	121
TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice	121
The visuomotor transformations underlying target-directed behavior	120
Fluorescence detection of dopamine signaling to the primate striatum in relation to stimulus–reward associations	120
On peer review—then, now, and soon to be?	120
Phylogenetic evidence clarifies the history of the extrusion of Indochina	120
Balance and imbalance in biogeochemical cycles reflect the operation of closed, exchange, and open sets	120
Endurance athletes hiding in plain sight in the high Andes	119
Conserving rhinoceros in the face of disease	119
β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells	118
Retraction for Li et al., Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells	118
Wandering mastodons reveal the complexity of Ice Age extinctions	118
Extremal structures with embedded prefailure indicators	118
Propulsive cell entry diverts pathogens from immune degradation by remodeling the phagocytic synapse	118
The decade-long growth of government-authored news media in China under Xi Jinping	118

A multilocus perspective on the evolutionary dynamics of multistrain pathogens	118
Pseudogap in electron-doped cuprates: Strong correlation leading to band splitting	117
Combinations of slow-translating codon clusters can increase mRNA half-life in Saccharomyces cerevisiae	117
Structural basis of higher order oligomerization of KSHV inhibitor of cGAS	117
The origin of color categories	117
In This Issue	116
Ultrafast transient absorption spectra and kinetics of human blue cone visual pigment at room temperature	116
Modes of Pangean lake level cyclicity driven by astronomical climate pacing modulated by continental position and p CO2	116
Trojan horse peptide conjugates remodel the activity spectrum of clinical antibiotics	115
Modeling DNA methyltransferase function to predict epigenetic correlation patterns in healthy and cancer cells	115
Slower swimming promotes chemotactic encounters between bacteria and small phytoplankton	115
Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae	114
Correction for Magesh et al., Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species	113
Photodissociation of dicarbon: How nature breaks an unusual multiple bond	113
Orc6 is a component of the replication fork and enables efficient mismatch repair	113
Chemometrics and genome mining reveal an unprecedented family of sugar acid–containing fungal nonribosomal cyclodepsipeptides	113
Circadian clock control of interactions between eIF2α kinase CPC-3 and GCN1 with ribosomes regulates rhythmic translation initiation	113
AlphaFold2-based prediction of the co-condensation propensity of proteins	113
Quantifying the impact of air pollution from coal-fired electricity generation on crop productivity in India	113
The global succinylation of SARS-CoV-2–infected host cells reveals drug targets	112
Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak–Keller–Segel chemotaxis model	112
Bias in machine learning models can be significantly mitigated by careful training: Evidence from neuroimaging studies	112
Synergetic collision and space separation in microfluidic chip for efficient affinity-discriminated molecular selection	111
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells	111
A randomized trial of behavioral interventions yielding sustained reductions in distracted driving	111
Unproctored online exams provide meaningful assessment of student learning	111
Minority salience and the overestimation of individuals from minority groups in perception and memory	110
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson’s disease	110
Nucleocytoplasmic trafficking and turnover mechanisms of BRASSINAZOLE RESISTANT1 in Arabidopsis thaliana	110
Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification	110
National religiosity eases the psychological burden of poverty	110
A heritable iron memory enables decision-making in Escherichia coli	110
Correlated substitutions reveal SARS-like coronaviruses recombine frequently with a diverse set of structured gene pools	110
Indigenous Knowledge as a sole data source in habitat selection functions	110
Observing heroic behavior and its influencing factors in immersive virtual environments	109
Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy	109
People mistake the internet’s knowledge for their own	109
Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts	109
Identification of KU-55933 as an anti-atherosclerosis compound by using a hemodynamic-based high-throughput drug screening platform	109
Contraception ends the genetic maintenance of human same-sex sexual behavior	108
Parameters of clustered suboptimal miRNA biogenesis	108
NURR1 expression regulates retinal pigment epithelial–mesenchymal transition and age-related macular degeneration phenotypes	108
Biodiversity mitigates drought effects in the decomposer system across biomes	107
Correction to Supporting Information for Ikeda et al., Seesaw protein: Design of a protein that adopts interconvertible alternative functional conformations and its dynamics	107
Oligopoly competition between satellite constellations will reduce economic welfare from orbit use	106
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses	106
Two-pore channels regulate endomembrane tension to enable remodeling and resolution of phagolysosomes	106
The intracellular Ca2+channel TRPML3 is a PI3P effector that regulates autophagosome biogenesis	106
RNA m 6 A demethylase ALKBH5 regulates the development of γδ T cells	106
In vitro investigation of protein assembly by combined microscopy and infrared spectroscopy at the nanometer scale	105
In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousness	105
Cytoplasmic stirring by active carpets	104
Functional alterations in cortical processing of speech in glioma-infiltrated cortex	104
Protein dynamics underlies strong temperature dependence of heat receptors	104
Simulating COVID-19 classroom transmission on a university campus	104
Genome-wide detection of human variants that disrupt intronic branchpoints	104
Dual-inhibitory domain iCARs improve the efficiency of the AND-NOT gate CAR T strategy	103
Exploiting breakdown in nonhost effector–target interactions to boost host disease resistance	103
Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling	103
Promoting C–F bond activation via proton donor for CF 4 decomposition	102
Identification of two archaeal GDGT lipid–modifying proteins reveals diverse microbes capable of GMGT biosynthesis and modification	101
Global monitoring of the impact of the COVID-19 pandemic through online surveys sampled from the Facebook user base	101
Cell–cell contact landscapes in Xenopus gastrula tissues	101
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis	100
Antiprion systems in yeast cooperate to cure or prevent the generation of nearly all [ PSI + ] and [URE3] prions	100
Starvation induces shrinkage of the bacterial cytoplasm	99
Dual membrane-spanning anti-sigma factors regulate vesiculation in Bacteroides thetaiotaomicron	99
LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway	99
Gap junction–transported cAMP from the niche controls stem cell progeny differentiation	99
Ride-hailing technology mitigates effects of driver racial discrimination, but effects of residential segregation persist	99
Arabidopsis protein S -acyl transferases positively mediate BR signaling through S -acylation of BSK1	98
Single hormone or synthetic agonist induces Gs/Gicoupling selectivity of EP receptors via distinct binding modes and propagating paths	98
False discovery rate control in genome-wide association studies with population structure	98
Transcranial magnetic stimulation to frontal but not occipital cortex disrupts endogenous attention	98
Quantitative comparison of nuclear transport inhibition by SARS coronavirus ORF6 reveals the importance of oligomerization	97
Comparing expert elicitation and model-based probabilistic technology cost forecasts for the energy transition	97
Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage	97
Bacterial lifestyle shapes pangenomes	96
A bacterial pigment provides cross-species protection from H 2 O 2 - and neutrophil-mediated killing	96
Atmospheric variability contributes to increasing wildfire weather but not as much as global warming	96
Part of the gender gap in voting for Democrats arises because a higher proportion of women than men voters are Black	96
Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2− breast tumor cells	96
Dominance of felsic continental crust on Earth after 3 billion years ago is recorded by vanadium isotopes	96
Tsg101 mimicry of canonical E2 enzymes underlies its role in ubiquitin signaling	96
In This Issue	96
Photomolecular effect: Visible light interaction with air–water interface	96
Symmetric activation and modulation of the human calcium-sensing receptor	95
Large contribution of biomass burning emissions to ozone throughout the global remote troposphere	95
Reduced physiological plasticity in a fish adapted to stable temperatures	95
Emergent behaviors of buckling-driven elasto-active structures	95
Long-term employment and health effects of active labor market programs	94
Cell–matrix feedback controls stretch-induced cellular memory and fibroblast activation	94
Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia	94
The case and context for atmospheric methane as an exoplanet biosignature	94
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy	93