Proceedings of the National Academy of Sciences of the United States o

Article	Citations
A degradable form of polyoma small T antigen reveals the high specificity of TAZ in regulating gene expression	973
Revealing the structure of snowflakes using acoustic levitation	654
Higher-order effects, continuous species interactions, and trait evolution shape microbial spatial dynamics	525
Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis	458
Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis	431
GPCR–MAPK signaling pathways underpin fitness trade-offs in whitefly	430
Tungsten is utilized for lactate consumption and SCFA production by a dominant human gut microbe Eubacterium limosum	417
Depressive symptoms during the transition to adolescence: Left hippocampal volume as a marker of social context sensitivity	398
Identification of two archaeal GDGT lipid–modifying proteins reveals diverse microbes capable of GMGT biosynthesis and modification	387
National religiosity eases the psychological burden of poverty	377
Integrating life history and behavioral aging in the wild	360
Cas9-mediated gene-editing frequency in microalgae is doubled by harnessing the interaction between importin α and phytopathogenic NLSs	359
Bottlenose dolphin mothers modify signature whistles in the presence of their own calves	325
Deep silicification–assisted long-term preservation of structural and genomic information across biospecies: From micro to macro	316
Kinetic pathways of solid–solid phase transitions dictated by short-range interactions	316
Accurate identification and mechanistic evaluation of pathogenic missense variants with Rhapsody-2	288
Greener skies? The quest for sustainable flying	287
Symmetric activation and modulation of the human calcium-sensing receptor	286
Atomic resolution structure of full-length human insulin fibrils	272
Identification of KU-55933 as an anti-atherosclerosis compound by using a hemodynamic-based high-throughput drug screening platform	259
Croquemort elicits activation of the immune deficiency pathway in ticks	257
Memory’s gatekeeper: The role of PFC in the encoding of congruent events	255
Functional redundancy in the toxic pathway of Bt protein Cry1Ab, but not Cry1Fa, against the Asian corn borer	252
Empowering genome-wide association studies via a visualizable test based on the regional association score	248
Roughness-dependent scaling of the contact area and separation gap with pressure for glassy polymers	240

Stomatal patchiness and cellular computing	239
Retraction for Li et al., Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells	238
Early life lead exposure from private well water increases juvenile delinquency risk among US teens	236
Modeling DNA methyltransferase function to predict epigenetic correlation patterns in healthy and cancer cells	232
Quantitative comparison of nuclear transport inhibition by SARS coronavirus ORF6 reveals the importance of oligomerization	229
Circadian clock control of interactions between eIF2α kinase CPC-3 and GCN1 with ribosomes regulates rhythmic translation initiation	224
Individuals benefit individual out-group members rather than harm in-group members	221
Mercury’s complex legacy	219
Endurance athletes hiding in plain sight in the high Andes	217
Insurance and climate risks: Policy lessons from three bounding scenarios	211
Correction for Magesh et al., Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species	211
Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB	210
The origin of color categories	209
Glucuronic acid confers colonization advantage to enteric pathogens	209
Aberrant neuronal hyperactivation causes an age-dependent behavioral decline in Caenorhabditis elegans	208
Correction to Supporting Information for Ikeda et al., Seesaw protein: Design of a protein that adopts interconvertible alternative functional conformations and its dynamics	205
A skin-interfaced wireless wearable device and data analytics approach for sleep-stage and disorder detection	199
Ciliary localization of a light-activated neuronal GPCR shapes behavior	198
Untangling the CD4 T cell response to the microbiota	197
Investigating 3D microbial community dynamics of the rhizosphere using quantitative phase and fluorescence microscopy	197
Late Cretaceous community structure changed before the asteroid	195
Impression management in research reporting: When effects are not really as pronounced as claimed	194
Thermodynamic consistency of autocatalytic cycles	193
Directional water navigation and reallocation in Tillandsia capitata	188
Correction for Garaizar et al., Toward understanding lipid reorganization in RNA lipid nanoparticles in acidic environments	186
An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis	186
Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage	185
Modeling blood metabolite homeostatic levels reduces sample heterogeneity across cohorts	185
Correction to Supporting Information for Bardy et al., Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro	183
Photoreduction of mercuric bromides in polar ice	183
Methodological and conceptual considerations of the TCM evolution	183
Clocking out and letting go to unleash green biotech applications in a photosynthetic host	181
Resilience of deep aquifer microbial communities to seasonal hydrological fluctuations	177
TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice	174
Adaptive DNA amplification of synthetic gene circuit opens a way to overcome cancer chemoresistance	170
Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia	169
Indigenous Knowledge as a sole data source in habitat selection functions	168
Integrative spatiotemporal modeling of biomolecular processes: Application to the assembly of the nuclear pore complex	167
How defective mitochondrial electrical activity leads to inherited blindness	165
Breaking the symmetry of cell contractility drives tubulogenesis via CXCL1 polarization	163
Trojan horse peptide conjugates remodel the activity spectrum of clinical antibiotics	162
Graphene nanoripples enable unexpected catalytic reactivity	162
Climate warming drives population trajectories of freshwater fish	161
Prolonged exertion of self-control causes increased sleep-like frontal brain activity and changes in aggressivity and punishment	160
Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease	160
Thermo-photo catalytic anode process for carbonate-superstructured solid fuel cells	160
Long-term employment and health effects of active labor market programs	159
In This Issue	158
DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8	158
Accounting for spatial sampling patterns in Bayesian phylogeography	157

Proactive or reactive? Neural oscillatory insight into the leader–follower dynamics of early infant–caregiver interaction	156
Fluorescence detection of dopamine signaling to the primate striatum in relation to stimulus–reward associations	153
Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness	153
Pinning down a perpetrator in postsurgical eye pain	152
A randomized trial of behavioral interventions yielding sustained reductions in distracted driving	152
Theory and observations of the interaction between magnetohydrodynamic waves and shocks	152
BRD9 functions as an HIV-1 latency regulatory factor	152
Correction for Ahituv et al., Starch-rich plant foods 780,000 y ago: Evidence from Acheulian percussive stone tools	151
AlphaFold2-based prediction of the co-condensation propensity of proteins	151
Hidden in plain sight: (Re)definition of a key lepidopteran color patterning gene	151
Touching the classical scaling in penetrative convection	149
Molecular patterns of matrix protein 1 (M1): A strong predictor of adaptive evolution in H9N2 avian influenza viruses	148
Independent transitions to fully planktonic life cycles shaped the global distribution of medusozoans in the epipelagic zone	148
Differential elimination of marked sex chromosomes enables production of nontransgenic male mosquitoes in a single strain	147
Using neuroimaging genomics to investigate the evolution of human brain structure	147
Identifying regulation with adversarial surrogates	146
Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+ -activated large-conductance K + channels and motor coordination	145
β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells	145
Vulnerability to natural disasters and sustainable consumption: Unraveling political and regional differences	145
IL-1 receptor antagonism reveals a yin-yang relationship between NFκB and interferon signaling in chronic lymphocytic leukemia	144
The Titanic question in TB control: Should we worry about the bummock?	144
Oligopoly competition between satellite constellations will reduce economic welfare from orbit use	141
Persistent deep water anoxia in the eastern South Atlantic during the last ice age	139
A sodium-dependent trehalose transporter contributes to anhydrobiosis in insect cell line, Pv11	138
Thermoelectricity, metallic liquidity, and magnetohydrodynamics	137
Single-neuron bursts encode pathological oscillations in subcortical nuclei of patients with Parkinson’s disease and essential tremor	137
Gap junction–transported cAMP from the niche controls stem cell progeny differentiation	137
Ultrafast transient absorption spectra and kinetics of human blue cone visual pigment at room temperature	136
Tsg101 mimicry of canonical E2 enzymes underlies its role in ubiquitin signaling	136
Propulsive cell entry diverts pathogens from immune degradation by remodeling the phagocytic synapse	136
Phylogenomics of the tetraploid Hawaiian lobeliads: Implications for their origin, dispersal history, and adaptive radiation	136
The James Webb Space Telescope prompts a rethink of how galaxies form	135
Modeling the population-level impact of a third dose of MMR vaccine on a mumps outbreak at the University of Iowa	135
Revealing land control dynamics in emerging agricultural frontiers	134
Balance and imbalance in biogeochemical cycles reflect the operation of closed, exchange, and open sets	133
Part of the gender gap in voting for Democrats arises because a higher proportion of women than men voters are Black	133
Observing heroic behavior and its influencing factors in immersive virtual environments	133
Arabidopsis protein S -acyl transferases positively mediate BR signaling through S -acylation of BSK1	132
The decade-long growth of government-authored news media in China under Xi Jinping	131
High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma	130
Dynamic early recruitment of GAK–Hsc70 regulates coated pit maturation	130
Consistently estimating network statistics using aggregated relational data	130
NURR1 expression regulates retinal pigment epithelial–mesenchymal transition and age-related macular degeneration phenotypes	129
MBD2a–NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression	129
Band gap opening of metallic single-walled carbon nanotubes via noncovalent symmetry breaking	129
The retrotransposon R2 maintains Drosophila ribosomal DNA repeats	128
Reversal of an existing hearing loss by gene activation in Spns2 mutant mice	127
The structural origin of the efficient photochromism in natural minerals	127
Simulating institutional heterogeneity in sustainability science	126
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy	126
Green ammonia could produce climate-friendly ways to store energy and fertilize farms	126
Reply to Apanovich and Weeks: Exceptions exist, as recognized in the paper, but are too rare to challenge the original findings	126
Engineered bacteria that self-assemble bioglass polysilicate coatings display enhanced light focusing	125
GmEID1 modulates light signaling through the Evening Complex to control flowering time and yield in soybean	125
Alternative cGAS signaling promotes herpes simplex encephalitis	125
Ride-hailing technology mitigates effects of driver racial discrimination, but effects of residential segregation persist	125
Strong connectivity in real directed networks	125
Slope classicality in higher Coleman theory via highest weight vectors in completed cohomology	125
Temporal and spatial distribution of health, labor, and crop benefits of climate change mitigation in the United States	124
Simple, fast, and flexible framework for matrix completion with infinite width neural networks	124
The visuomotor transformations underlying target-directed behavior	123
Kids adopt different ways of coping in wake of the pandemic	123
Correction to Supporting Information for Ahuja et al., Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease	123
Multiple dimeric structures and strand-swap dimerization of E-cadherin in solution visualized by high-speed atomic force microscopy	122
Are Americans less likely to reply to emails from Black people relative to White people?	121
An IL-23-STAT4 pathway is required for the proinflammatory function of classical dendritic cells during CNS inflammation	120
Antiprion systems in yeast cooperate to cure or prevent the generation of nearly all [ PSI + ] and [URE3] prions	120
Longevity, demographic characteristics, and socio-economic status are linked to triiodothyronine levels in the general population	120
Modeling for COVID-19 college reopening decisions: Cornell, a case study	117
Heparin is essential for optimal cell signaling by FGF21 and for regulation of βKlotho cellular stability	117
Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic	117
The new W family reconstructs the evolution of MHC genes	116
Defective myelination in an RNA polymerase III mutant leukodystrophic mouse	116
TGM2-mediated histone transglutamination is dictated by steric accessibility	116
A heritable iron memory enables decision-making in Escherichia coli	116
Structural basis of higher order oligomerization of KSHV inhibitor of cGAS	116
Correction for Li et al., SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes	115
Wandering mastodons reveal the complexity of Ice Age extinctions	115
From the laboratory to the consumer: Innovation, supply chain, and adoption with applications to natural resources	115
Single hormone or synthetic agonist induces Gs/Gicoupling selectivity of EP receptors via distinct binding modes and propagating paths	114

Combinations of slow-translating codon clusters can increase mRNA half-life in Saccharomyces cerevisiae	114
Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family	114
Correction for Dar et al., Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma	114
The dual-process theory of moral judgment does not deny that people can make compromise judgments	113
Structural stability and thermodynamics of artistic composition	113
In This Issue	112
Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia	111
Pathways to parasitic strategies in ants	110
Orc6 is a component of the replication fork and enables efficient mismatch repair	110
Cytosolic and mitochondrial ribosomal proteins mediate the locust phase transition via divergence of translational profiles	110
High-throughput measurement of elastic moduli of microfibers by rope coiling	109
Spiritual over physical formidability determines willingness to fight and sacrifice through loyalty in cross-cultural populations	109
The evidence remains clear: SARS-CoV-2 emerged via the wildlife trade	109
Correction for Shanmugapriya et al., Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170	108
Modes of Pangean lake level cyclicity driven by astronomical climate pacing modulated by continental position and p CO2	108
Self-consistent dispersal puts tight constraints on the spatiotemporal organization of species-rich metacommunities	108
Human ERG oncoprotein represses a Drosophila LIM domain binding protein–coding gene Chip	108
Concerted evolution of metabolic rate, economics of mating, ecology, and pace of life across seed beetles	108
Social mindfulness for global environmental sustainability?	107
Serum apolipoprotein A-I depletion is causative to silica nanoparticles–induced cardiovascular damage	106
How can we reform the STEM tenure system for the 21st Century?	106
Correction for Andreasson et al., Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular switches	106
In This Issue	106
Exploring the associations between discrimination, coping, skin tone, and the psychosocial health of young adults of color	106
Challenging the Bayesian confidence hypothesis in perceptual decision-making	105
Probing both sides of the story	105
Simulating COVID-19 classroom transmission on a university campus	104
Piezo mechanosensory channels regulate centrosome integrity and mitotic entry	104
Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak–Keller–Segel chemotaxis model	104
Genomic adaptations for arboreal locomotion in Asian flying treefrogs	103
Membrane association of active genes organizes the chloroplast nucleoid structure	103
Architecture-driven quantitative nanoscopy maps cytoskeleton remodeling	103
Pressure pushes tRNA Lys3 into excited conformational states	103
Redox conditions correlated with vibronic coupling modulate quantum beats in photosynthetic pigment–protein complexes	103
Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders	102
Targeting spike glycans to inhibit SARS-CoV2 viral entry	102
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses	101
Thermodynamic feasibility of shipboard conversion of marine plastics to blue diesel for self-powered ocean cleanup	101
Slower swimming promotes chemotactic encounters between bacteria and small phytoplankton	101
Photodissociation of dicarbon: How nature breaks an unusual multiple bond	101
Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels	100
Reply to Kodner et al.: Fundamental misunderstanding of both model and methods	100
Conserving rhinoceros in the face of disease	99
Symmetries and synchronization from whole-neural activity in the Caenorhabditis elegans connectome: Integration of functional and structural networks	98
A multilocus perspective on the evolutionary dynamics of multistrain pathogens	98
Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2	98
The tumor suppressor RASSF8: A WAVE interaction partner controlling migration and cohesion of invasive border cells in Drosophila	98
The global succinylation of SARS-CoV-2–infected host cells reveals drug targets	98
ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth	98
Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+breast cancer by ceramide-loaded nanoparticles	97
Heterogenous biofilm mass-transport model replicates periphery sequestration of antibiotics in Pseudomonas aeruginosa PAO1 microcolonies	97
Larger images are better remembered during naturalistic encoding	97
Correction to Gaffney et al., Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein	97
Chemometrics and genome mining reveal an unprecedented family of sugar acid–containing fungal nonribosomal cyclodepsipeptides	97
Indigenous territories and protected areas are crucial for ecosystem connectivity in the Amazon basin	96
Retraction for Goswami et al., A bifunctional tRNA import receptor from Leishmania mitochondria	96
Gadolinium enhancement of cranial nerves: Implications for interstitial fluid drainage from brainstem into cranial nerves in humans	96
Semantic change in adults is not primarily a generational phenomenon	96
N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells	95
Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson’s disease	95
Genome-wide detection of human variants that disrupt intronic branchpoints	95
Fucoid brown algae inject fucoidan carbon into the ocean	95
Conservation management strategy impacts inbreeding and mutation load in scimitar-horned oryx	95
Yeast centrosomes act as organizing centers to promote Polo kinase–mediated adaptation to persistent DNA damage	95
Rab3 mediates a pathway for endocytic sorting and plasma membrane recycling of ordered microdomains	94
In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse	94
On the microstructural origin of brain white matter hydraulic permeability	94
The quorum-sensing peptidic inhibitor rescues host immune system eradication: A novel infectivity mechanism	94
In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousness	94
Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex	94
Cell–matrix feedback controls stretch-induced cellular memory and fibroblast activation	94
Crosslinguistic word order variation reflects evolutionary pressures of dependency and information locality	94
Species invasion progressively disrupts the trophic structure of native food webs	93
Contraception ends the genetic maintenance of human same-sex sexual behavior	93
Emotional (in)stability: Neuroticism is associated with increased variability in negative emotion after all	93
Atmospheric variability contributes to increasing wildfire weather but not as much as global warming	93
Sound-mediated nucleation and growth of amyloid fibrils	93
Healthy sleep durations appear to vary across cultures	93
Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries	93
Multiscale modeling shows how 2’-deoxy-ATP rescues ventricular function in heart failure	93
Direct measuring of single–heterogeneous bubble nucleation mediated by surface topology	93
SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands	92
Polymorphic transposable elements contribute to variation in recombination landscapes	92
The gender gap in the ownership of promising land	92
A bacterial pigment provides cross-species protection from H 2 O 2 - and neutrophil-mediated killing	92
Data-driven classification of ligand unbinding pathways	92
Three common assumptions about inflammation, aging, and health that are probably wrong	92
Lateral olivocochlear neurons modulate cochlear responses to noise exposure	92
Generalized scaling of spin qubit coherence in over 12,000 host materials	91
Predictive phage therapy for Escherichia coli urinary tract infections: Cocktail selection for therapy based on machine learning models	91
Topography affects not only interhemispheric asymmetry of westerly winds and thus storminess but also ocean circulation	91
Explaining happiness trends in Europe	90
NOTUM-mediated WNT silencing drives extravillous trophoblast cell lineage development	90
Phylogenetic evidence clarifies the history of the extrusion of Indochina	90
Transforming growth factor-β signaling governs the differentiation program of extravillous trophoblasts in the developing human placenta	90