OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Transcription Factor NRF2 in Endothelial Functions	51
Regulation of Retrotransposons in Drosophila melanogaster Somatic Tissues	45
Reduced Expression of the Tissue-Specific Oct-1L Isoform Exerts an Antitumor Effect on Namalwa Burkitt’s Lymphoma Cells	45
OLR1 Knockdown Mitigates Traumatic-Hemorrhagic Shock-Induced Liver Injury by Inhibiting the TLR4/MYD88 Pathway and NLRP3 Inflammasome Activation	25
Synthesis and Antimicrobial Activity of Thiosulfinates and Allicin Analogues	24
Recombinant VLP Vaccines Synthesized in Plant Expression Systems: Current Updates and Prospects	23
Protective Effects of Luteolin in an In Vitro Model of Ethanol-Induced Gastric Epithelial Injury: Insights into ROS Modulation and Inflammatory Response	21
Marine Fungi: In Search of New Antibacterial Drugs	21
The Redox-Catalytic Properties of Cobalamins	21
The Antioxidant and Geroprotective Properties of an Extract of Mountain Ash (Sorbus aucuparia L.) Fruits	19
Exploration of Role of Lycorine against Endometrial Cancer Based on Network Pharmacology, Molecular Docking, and In Vitro Validation	18
Unraveling Cancer Progression in Oral Squamous Cell Carcinoma through Regulatory Network Analysis; miRNA-Target Gene Interaction	14
New Epigenetic Markers of Age-Dependent Changes in the Cardiovascular System	13
DNA Probes for Analysis of the Activity of Key Enzymes of the Base Excision DNA Repair Pathway in Human Cells	12
Landscape of KRAS, BRAF, and PIK3CA Mutations and Clinical Features of EBV-Associated and Microsatellite Unstable Gastric Cancer	12
Methods to Increase the Efficiency of Knock-in of a Construct Encoding the HIV-1 Fusion Inhibitor, MT-C34 Peptide, into the CXCR4 Locus in the CEM/R5 T Cell Line	12
Spatial Models of Piezo Proteins and Protein‒Protein Interaction Networks in Trichoplax Animals (Placozoa)	11
A Bioinformatics Method for Identification of Human Proteases Active against Viral Envelope Glycoproteins: A Case Study on the SARS-CoV-2 Spike Protein	10
Cytotoxicity Studies of 5-Arylaminouracil Derivatives	10
Melatonin Enhances the Effect of ABT-737 in Acute Monocytic Leukemia THP-1 Cells	10
Regulatory Potential of SNP Markers in Genes of DNA Repair Systems	9
Spatial Transcriptomics for Molecular Dissecting of the Tumor Immune Microenvironment: Comparison of Commercially Available Platforms	9
NRP1 Promotes Chronic Lymphocytic Leukemia Progression by Regulating Lipid Synthesis via the EGFR/Akt/SREBP-1 Pathway	9
Improvement of Crops Using the CRISPR/Cas System: New Target Genes	8
Heat Shock Proteins in Plant Protection from Oxidative Stress	8

Leukocyte Telomere Length as a Marker for Differentiating Carcinoma in Situ of the Bladder from Non-Carcinoma In Situ Bladder Tumors	8
Identification of Functionally Significant Polymorphic Variants in miRNA Genes in Carotid Atherosclerosis	7
Genetic Aspects of the Application of Tissue-Engineered Constructs in Regenerative Therapy in Cardiology: An Analytical Review	7
Relationships between Cxcl12, Tweak, Notch1, and Yap mRNA Expression Levels in Molecular Mechanisms of Liver Fibrogenesis	7
Establishment and Validation of Cancer Cell Lines with HER2 Receptor Gene Deletion	7
Biochip for Determination of 92 Human Y-Chromosome Haplogroups by SNP Markers and Frequency Distribution of These Haplogroups in Slavic Population of European Russia	6
METTL3 Contributes to the Advancement of Non-Small Cell Lung Cancer by Regulating m6A RNA Methylation-Mediated Degradation of FBXO33	6
Dynamic Changes in the Activities and Contents of Particular Proteasome Forms in the Cerebral Cortex of C57BL/6 Mice during Aging	6
Interaction of SENP6 with PINK1 Promotes Temozolomide Resistance in Neuroglioma Cells via Inducing the Mitophagy	6
Gut Microbiota in Colorectal Cancer Carcinogenesis: The Evolution of Hypotheses	5
Genotype-Specific Features of Cold-Induced Sweetening Process Regulation in Potato Varieties Nikulinsky, Symfonia, and Nevsky	5
Phase Separation of Purified Human LSM4 Protein	5
The Effects of the Hydrogen Sulfide Donor GYY4137 on the Proteasome Pool of Colorectal Cancer Cells	5
Functional Activity of Transcription Factors Is Associated with Detection Frequency of Human Open Chromatin Regions	5
The Expression of TP53TG1, LINC00342, MALAT1, H19, and MEG3 Long Noncoding RNAs in Type 2 diabetes mellitus	5
CRISPR Interference in Regulation of Bacterial Gene Expression	5
The Level of Methylation in the Promoter Regions of DNA Repair Genes in Chronically Exposed People	5
Transcription Factor Sp1 in the Expression of Genes Encoding Components of Mapk, JAK/STAT, and PI3K/Akt Signaling Pathways	5
Identification of Melittin-Like Proteins with a Molecular Weight of 67 kDa that Interact with Na+/K+-ATPase	4
Mechanism of Leakage in Phosphatidylserine-Containing Membranes by Melittin	4
Role of Mitochondria in Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease	4
Yeast as a Biochemical Model for Diseases Associated with Impaired Intracellular Proteolytic Systems	4
Method of Inducible Knockdown of Essential Genes in OSC Cell Culture of Drosophila melanogaster	4
Zebrafish Xenographs in Oncology and Personalized Medicine	4
MLE (DHX9) Helicase Regulates the Expression of Constitutive and Inducible Isoforms of the Conserved Nuclear Receptor FTZ-F1 (NR5A3)	4
Glial Progenitor Cell Therapy Improves Mitochondrial Function in the Hippocampus of 5xFAD Mice, but Does Not Restore the Multiscale Structure of Behavioral Stress Response	4
Comparative Analysis of Family A DNA-Polymerases as a Searching Tool for Enzymes with New Properties	4
Improving the Efficiency and Safety of Human CCR5 Gene Editing by Selection of Optimal Guide RNAs for SpCAS9 and CAS12A	4
Exploring the Role and Mechanism of miRNA Dysregulation in Chronic Intermittent Hypoxia-Induced Cognitive Decline in Rats	4
Erratum to: Promoter Mutation of the bZIP Transcription Factor BdABF Accelerates Flowering in Brachypodium distachyon	4
Methylation Status of Apoptosis Genes and Intensity of Apoptotic Death of Peripheral Blood Lymphocytes in Persons Chronically Exposed to Radiation	4
Structural Elements of DNA and RNA Eukaryotic Expression Vectors for In Vitro and In Vivo Genome Editor Delivery	4
Full and D-BOX-Deficient PTTG1 Isoforms: Effects on Cell Proliferation	4
Amidothiazole Derivatives of (+)-Usnic Acid Effectively Inhibit TDP1 and Sensitize Tumor Cells to the Effects of Topotecan	4
Type II CRISPR–Cas System Nucleases: A Pipeline for Prediction and In Vitro Characterization	4
Mechanism of Oxidative Stress Inducing Pyroptosis by Activating the NLRP3/Caspase-1/GSDMD Pathway in Lens Epithelial Cells under High Glucose Environment	4
The Semi-Essential (SE) Region of Bacteriophage Mu and Its Role in Host-Fitness Advantage	4
CpG Traffic Lights Are Involved in Active DNA Demethylation	4
DNA Methylation Profiling in Aneurysm and Comorbid Atherosclerosis of the Ascending Aorta	4
Antiglycation Activity of Isoindole Derivatives and Its Prediction Using Frontier Molecular Orbital Energies	4
The Structural Features of Skeletal Muscle Titin Aggregates	4
The Landscape and Regulatory Mechanisms of Aberrant Alternative Splicing Events in Adenomyosis	4
Label-Free Optical Biosensor for Analysis of Binding Kinetics of Smart Nanomaterials with Ligands	4
Gene Expression Analysis of miR-142-3p/BMAL1/PPARA and miR-24-3p/PER2/PPARG Pathways: Insights into the Link between Short Sleep Duration and Obesity in Humans	4
Identification of Stable Reference Genes for RT-qPCR in Golden Syrian Hamster under Vaccination and Infection Conditions	4
The Proteome of Extracellular Membrane Vesicles from Bacillus pumilus 3-19	4
Poly(ADP-Ribose) Polymerases 1 and 2: Classical Functions and Interaction with New Histone Poly(ADP-Ribosyl)ation Factor HPF1	3
Families of Type III Restriction Endonucleases Based on Sequence Similarity of the Catalytic Domain	3
Genome Stability of Bacillus velezensis after Two-Year Exposure in Open Space	3
Repair of Double-Stranded DNA Breaks Generated by CRISPR–Cas9 in Pseudomonas putida KT2440	3

Regulating Kynurenine-Mediated Suppression of CLOCK by miR-30b-5p in Knee Osteoarthritis	3
Toxin–Antitoxin Systems: Formation of Genetic Networks of Human Microbiome Bacteria and Prospects for Application	3
Virus-Like Particles Carrying HIV-1 Env with a Modulated Glycan Composition	3
Angiotensin II Type I Receptor—168A/G Polymorphism Is Associated with Increased the Risk of Glioma in Turkish Population	3
Spatial Reconstruction of TRPC Mechanoreceptors of the Ctenophore Mnemiopsis leidyi A. Agassiz, 1865	3
Methylation of Long Noncoding RNA Genes SNHG6, SNHG12, and TINCR in Ovarian Cancer	3
JMJD3 Exerts Oncorepressor Activity in Acute Promyelocytic Leukemia by Promoting PU.1 Expression	3
Analogs and Conjugates of Natural Proline-Arginine-Rich Antimicrobial Peptides: Application Potential	3
Digital PCR as a Highly Sensitive Diagnostic Tool: A Review	3
Long Noncoding RNAs MEG3, TUG1, and hsa-miR-21-3p Are Potential Diagnostic Biomarkers for Coronary Artery Disease	3
Triosephosphate Isomerase Inhibition by Resveratrol: A New Mechanism of Anti-Glycolysis in Breast Cancer	3
Influence of Homology Arm Length and Structure on the Efficiency of Long Transgene Integration into a Cleavage Site Induced by SpCas9 or AsCpf1	3
Effect of Usnic Acid-Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Used as Monotherapy or in Combination with Olaparib on Transplanted Tumors In Vivo	3
HIV Restriction Factor APOBEC3G and Prospects for Its Use in Gene Therapy for HIV	3
Unusual Dependence between Gene Expression and Negative Selection in Euplotes	3
Modeling Protein–Protein Interaction of the KNOTTED-LIKE HOMEOBOX 3 Protein Involved in Symbiotic Nodule Development in Medicago truncatula	3
Cloning of Mycoplasma gallisepticum Genome in Saccharomyces cerevisiae Cells	3
GeneLens: A Python Package Implementing Monte Carlo Machine Learning and Network Analysis Methods for Biomarker Discovery and Gene Functional Annotation	3
IMR-1 Restores Oxaliplatin Sensitivity in Gastric Cancer Resistant Cells by Inhibiting the Notch Signaling Pathway	3
Ubiquitin-Specific Protease 43 Promotes Degradation of Phenylalanine Hydroxylase in Mammalian Cells	2
Identification of Clinical Isolates of the Bacillus cereus Group and Their Characterization by Mass Spectrometry and Electron Microscopy	2
Genetically Modified Pigs as Organ Donors: Challenges and Prospects	2
Stochastic Packaging of Cas Proteins into Exosomes	2
Low-Molecular Thiols as a Factor Improving the Sensitivity of Escherichia coli Mutants with Impaired ADP–Heptose Synthesis to Antibiotics	2
Liraglutide, a GLP-1 Receptor Agonist, Enhances Proliferation and Secretory Function of Pancreatic β-Cells with Activated ABCC8	2
Modern Approaches to Anti-EGFR Therapy	2
Geometric Approach to Phylogeographic Analysis Molecular Genetic Sequences: Principal Components and Dendrograms	2
Knockout of Hsp70 Genes Modulates Age-Related Transcriptomic Changes in Leg Muscles and Reduces the Locomotion Speed and Lifespan of Drosophila melanogaster	2
Neuronal Calcium Sensor-1: A Zinc/Redox-Dependent Protein of Nervous System Signaling Pathways	2
The NS1 Protein of the Tick-Borne Encephalitis Virus and Extracellular Vesicles from NS1-Expressing Cells: Effect on Expression of Genes of the Innate Immune Response in Neuroblastoma and Glioblastoma	2
Upregulation of MHC I Antigen Processing Machinery Gene Expression in Breast Cancer Cells by Trichostatin A	2
Error Correction Techniques in Synthetic Oligonucleotides and Synthetic DNA	2
Molecular Diagnostics of the Involvement of Visually Normal Mucosa in the Malignancy Process in Urothelial Bladder Cancer	2
Placental Tissue Transcriptomics as a Tool to Identify the Molecular Mechanisms of Great Obstetrical Syndromes	2
Insulator Protein CP190 Regulates Expression оf Spermatocyte Differentiation Genes in Drosophila melanogaster Male Germline	2
Dormancy: There and Back Again	2
Ac4C Acetylation Facilitates lncRNA MEG3 to Ameliorate Hyperglycemia-Induced Ferroptosis of Hippocampal Neurons	2
DNA Methylation Detection: Fluorescent and Colourimetric Methods Based on Methylation-Associated Restriction Endonucleases	2
Overexpression of MKRN2 Inhibits the Growth of Ovarian Cancer Cells	2
DNA Vaccine Technologies: Design and Delivery	2
Current Knowledge of Base Editing and Prime Editing	2
Genome Editing in Species of the Tribe Triticeae with the CRISPR/Cas System	2
Molecular Ion Channel Blockers of Influenza A and SARS-CoV-2 Viruses	2
Dynamics of Transgene Expression in the MVA Vaccine Vector under the Control of the p11, p13.5, pLEO160, p7.5, and mH5 Promoters and Independence of the Transgene Expression Level from the Insertion L	2
Physiological Media in Studies of Cell Metabolism	2
IL-8 Links NF-κB and Wnt/β-Catenin Pathways in Persistent Inflammatory Response Induced by Chronic Helicobacter pylori Infection	2
Changes in the Activity of Antioxidant Systems of Escherichia coli under Phosphate Starvation	2
Genetic and Molecular Characterization of a Dash Cryptochrome Homologous Gene from Antarctic Diatom Phaeodactylum tricornutum ICE-H	2
Factors Affecting the Stability of the Trimer of 2'-Deoxyuridine 5'-Triphosphate Nucleotide Hydrolase from Escherichia coli	2
On Immunological Studies at Sirius University of Science and Technology	2
Methylation of Regulatory Regions of DNA Repair Genes in Carotid Atherosclerosis	2
Allosteric Effects Upon Binding of Proteins and Antibiotics on DNA: History and the Present	2
DNA Double-Strand Break Repair System by a Mechanism of Non-Homologous End Joining Provides Resistance to DNA-Damaging and Oxidizing Stresses in the Yeast Debaryomyces hansenii	2
The Mechanism of Bimodal Effect of DL-Butyonine Sulfoximine on Constitutive Androstane and Pregnane X Receptors In Vitro	2
Expression Profiles of TRIM Family Genes in Neuronal and Glial Cell Cultures of Healthy Donors and Patients with Parkinson’s Disease under Normal Conditions and Upon Neuroinflammation	2
Spatial Organization of Chromatin of ZEB1 Gene Promoter Region in Pancreatic Ductal Adenocarcinoma Cells	2
Immunization of Mice with the pVAXrbd DNA Vaccine by Jet Injection Induces a Stronger Immune Response and Protection against SARS-CoV-2 Compared to Intramuscular Injection by Syringe	2
Genome Editing in Therapy of Genodermatoses	2
Cytochrome bd as Antioxidant Redox Enzyme	2
Genome-Wide Identification of Alternative Splicing and RNA-Binding Proteins Regulators Respond to Glutamine Therapy for Acute Kidney Injury	2
Elucidating the Effects of Aromatic Mutations on the RNA Binding Efficacy of CELF2 Protein	2
The Molecular and Genetic Mechanisms of Sex Determination in Poplar	2
The Effectiveness of STR Genotyping Depends on the Organic Carbon Content in Ancient Samples	2
Alterations in the Level of mRNA of TPH1, TPH2 Genes, Tryptophan Hydroxylase Activity and Serotonin Metabolism in Mouse Brain Five Days after Lipopolysaccharide Administration	2
Oncolytic Viruses in the Therapy of Lymphoproliferative Diseases	2
Mechanism of Thiocyanate Dehydrogenase Functioning Based on Structural Data	2
Overexpression of miR-101-3p Participates in DDP Resistance in NSCLC Cells by Inhibiting YWHAZ	2
CG10543 Protein Is Involved in the Regulation of Transcription of Ecdysone-Dependent Genes	2
Transgenesis in Worms: Candidates for an Ideal Model	2
Rapamycin Regulates Lipopolysaccharide-Induced Microglial Phagocytosis In Vitro	2
Expression of Long Noncoding RNAs and Protein-Coding Genes Involved in Oxidative Stress and Cell Senescence in Patients with Chronic Obstructive Pulmonary Disease	2
Components of Bacterial Cell Walls as Targets for Searching for New Antibacterial Compounds: Methods of Study	2
Molecular Mechanisms to Optimize Gene Translation Elongation Differ Significantly in Bacteria with and without Nonribosomal Peptides	2
Distribution of Antibiotic Resistance Genes in Microbial Communities: The Impact of Anthropogenic Pollution	2