OOIR: Observatory of International Research

Papers

(The TQCC of Minerva Medica is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Application and nursing effect analysis of negative pressure wound therapy combined with drip irrigation in the treatment of diabetic refractory wounds	62
Measurement of outer nuclear layer and inner/outer segment using spectral-domain optical coherence tomography in patients with diabetic retinopathy	51
Hepatic encephalophaty: management and diagnostic therapeutic assistance path of Ligurian Local Health Company 3 (ASL3)	50
Electroacupuncture regulates sperm motility in patients with asthenozoospermia: study protocol for a randomized sham-controlled clinical trial	31
AT1R gene polymorphism in coronary heart disease	30
Adiponectin alleviates non-alcoholic fatty liver injury via regulating oxidative stress in liver cells	26
Age-related differences in hemodynamics in brain dead donors: effects on liver transplantation in a single center	24
Optimized treatment of woven coronary artery by optical coherence tomography combined with coronary fractional flow reserve	21
Effect of psychological intervention combined with family model on postoperative rehabilitation in patients with cervical cancer	20
Shortwave diathermy in the management of chronic lymphedema following breast cancer surgery: proof-of-concept findings from a single-arm, pre-post, retrospective observational study	17
Neutrophil-to-lymphocyte ratio in bronchoalveolar lavage from IPF patients: a novel prognostic biomarker?	17
Metalloprotease ADAM10 inhibition mitigates acute liver injury via repression of intrahepatic inflammation	16
Speckle-tracking echocardiography: state of art and its applications	15
Impaired endogenous fibrinolysis status: a potential prognostic predictor in ischemic stroke	13
High-frequency ultrasound elastography improves the effect of determining the nature of lesions during the diagnosis of Hashimoto's thyroiditis and thyroid cancer	11
Anti-inflammatory role of vitamin D in muscle dysfunctions of patients with chronic obstructive pulmonary disease: a comprehensive review	11
LncRNA AFAP1-AS1 promotes the metastasis of prostate cancer	11
Therapeutic effect of double plasmapheresis combined with immunosuppressive agents on severe lupus nephritis	11
Expression and clinical significance of MCP-1 in serum of patients with chronic kidney disease undergoing maintenance hemodialysis	10
The comparison analysis of bloodstream infection caused by Klebsiella pneumoniae versus Escherichia coli: incidence, clinical distribution and drug resistance	10
Beyond the lung involvement in COVID-19 patients	9
COVID-19 mortality in Italy: gene and diet?	9
Exploration of arthroscopic treatment for ankle joint motion injuries	9
A case of laparoscopic right hemicolectomy for colon cancer	9
Alcohol use and rheumatoid arthritis: a poorly studied association	9

Application of dexmetomidine in gynecological laparoscopic surgery and its effect on S-100 β protein and cognitive function in patients	9
Analysis of the effect of lower limb nursing on prevention of deep venous thrombosis in long-term bedridden patients	9
The relationship between negative emotion of pregnant women in the second and third trimester of pregnancy and neonatal neurodevelopment	9
Strengths and pitfalls of brigatinib in non-small cell lung cancer patients' management	9
Effect of precision nursing model on aortic valve disease in elderly patients at high risk after transapical interventional aortic valve implantation	8
Effect of health nursing intervention on quality of life and complications of peptic ulcer patients on the basis of traditional Chinese medicine constitution identification	8
Strain-level resolution is needed to understand the putative pathogenic role of bacteria	8
Importance of central BP assessment in ISH of the young. Which devices are best suited for practical use?	8
Comparison of serum tumor markers combined with dual-source CT in the diagnosis of lung cancer	8
Intravascular lithotripsy-assisted carotid artery stenting for calcified carotid stenosis: a systematic review and meta-analysis	7
Meta-analysis of clinical efficacy and safety of yangxuenao granules combined with cholinesterase inhibitors in the treatment of vascular cognitive impairment	7
Clinical observation of Febuxostat in the treatment of gout patients with different body fat levels	7
Pulmonary hypertension in patients affected by sleep-related breathing disorders: up to date from the literature	7
Supplementary management of chronic Lyme disease with Pycnogenol®	7
The interplay between diabetes mellitus and chronic obstructive pulmonary disease	7
Retraction of: "Network meta-analysis: a new analysis tool of the experimental evidence"	7
Robotic pyelolithotomy for the treatment of large renal stones: a single-center experience over seven years	7
Efficacy of prone positioning in COVID-19 pneumonia according to radiological phenotypes	6
Down-regulation of miR-885 inhibits colorectal cancer progression by targeting PDCD5 through TGF-β/Smad3 signaling pathway	6
Delayed treatment with endostatin displays a protective role against pulmonary hypertension by targeting VEGF pathway	6
The application value of circulating tumor DNA methylation biomarkers in early diagnosis of non-small cell lung cancer	6
Expression of TIM-3 in rheumatoid arthritis peripheral blood regulatory T cells and clinical study of IL-17	6
Objective to explore the clinical application value of mobile nurse workstation in obstetrics and gynecology quality nursing service	6
Expression level of miR-383-5p in colorectal cancer patients following neoadjuvant chemotherapy and its clinical significance in the prognosis	6
Type 2 diabetes, heart failure and the treatment of their comorbidity	6
Effect of target-directed fluid therapy on hyponatremia and prognosis in patients with cervical spinal cord injury	6
A standard model for venous thrombosis. A quantum view	6
Application of rapid rehabilitation surgical concept in perioperative nursing of patients undergoing single-port thoracoscopic lobectomy	6
MiR-21 promotes renal injury in septic rats by regulating TGF-β1/Smad pathway	6
Study of Pseudomonas aeruginosa quorum-sensing signaling molecule N-3oxododecanoyl homoserine lactone suppresses human monocyte-derived dendritic cell maturation through PPARγ	5
Effect and clinical evaluation of butylphthalide combined with ureklin on ischemic low perfusion area in patients with acute cerebral infarction	5
Clinical significance of femoral cortical thickness parameters and trabecular density in the treatment of hip fracture in the elderly	5
Associations of intestinal barrier function, inflammatory factors and nutritional status of liver cancer patients with severity of disease and prognosis	5
Progress in clinical treatment and nursing of pediatric eosinophilic esophagitis	5
Integrative global co-expression analysis identifies key microRNA-target gene networks as key blood biomarkers for obesity	5
Liraglutide monotherapy and add on therapy on obese women with polycystic ovarian syndromes: a systematic review and meta-analysis	5
Current approach to the conservative management of arthrosis: results of the "Osteo-Experience" project	5
Effect observation and safety evaluation score of systematic health education nursing mode in knee arthritis nursing	5
Analysis of the application of contrast-enhanced ultrasound-guided prostate biopsy in early diagnosis of prostate cancer	5
Multi-organ support combined with a series of adjuvant therapies: a Chinese case report of pulmonary-renal syndrome due to granulomatosis with polyangiitis	5
CAPZA1 is low expressed in non-small cell lung cancer and contributed to tumor cell proliferation and metastasis	5
Decoding uterine leiomyosarcoma: is ultrasound diagnosis still a daunting challenge?	5
Long non-coding RNA FENDRR regulates proliferation, apoptosis and migration in high-glucose-induced human retinal endothelial cells via targeting miR-384/RHOA axis	5
Effect analysis of continuous care model in the management of chronic diseases in the elderly	5
Role of oxidative stress in the pathogenesis of COPD	5
Relationship between heart rate and central aortic blood pressure: implications for assessment and treatment of isolated systolic hypertension in the young	5
Cause analysis and nursing care of digestive tract reaction in patients with ovarian cancer during chemotherapy	5
The analysis of alcohol consumption during the severe acute respiratory syndrome Coronavirus 2 Italian lockdown	5
Obstructive sleep apnea-hypopnea syndrome and liver fibrosis	5
Safety and efficacy of direct oral anticoagulants (DOACs) in very elderly patients (≥85 years old) with non-valvular atrial fibrillation	4

Obesity and inflammatory response in moderate-to-severe acute respiratory distress syndrome: a single center pilot study	4
LncRNA ANRIL represses proliferation of oral squamous cell carcinoma cells through targeting MiR-99a	4
Fragmented QRS in dialysis patients: too simple to be truly useful or a potential prognostic and diagnostic tool?	4
Clinical study on nursing quality control in the operating room with comprehensive evaluation method	4
Observation on the effect of CSEA in elderly patients with fracture complicated with digestive ulcer and analysis of the incidence of adverse reactions	4
Flying to high-altitude destinations	4
Correlations of coronary artery disease degree with endothelial function and glucose metabolism in patients with type 2 diabetes mellitus complicated with coronary heart disease	4
Intraprocedural continuous saline infusion lines significantly reduce the incidence of acute kidney injury during endovascular procedures for stroke and myocardial infarction: evidence from a systemat	4
Treatment and clinical analysis of cerebral vasospasm after aneurysmal subarachnoid hemorrhage	4
The association of meal glycemic index/load with quantitative and qualitative indicators of sleep: a systematic review	4
Analysis of the clinical effect of pregabalin capsule combined with loratadine dispersible tablets in the treatment of uremic skin pruritus	4
Could anticoagulation therapy prior to SARS-CoV-2 infection prevent complications and the need for mechanical ventilation?	4
The order of degeneration of lumbar intervertebral disc and lumbar facet joint and its correlation with age	4
Reference value of magnetic resonance imaging and echocardiography in the diagnosis of pulmonary hypertension at high altitude	4
Effects of bevacizumab and capecitabine combined with intraperitoneal thermoperfusion chemotherapy on therapeutic effect, immunity and prognosis of gastric cancer patients	4
AFAP1-AS1 promotes the proliferation, migration and invasion of endometrial stromal cells from endometriosis through regulating the PI3K/AKT pathway	4
The treatment of adenomyosis-induced ovarian hyperstimulation syndrome with leuprolide	4
Clinical features and outcome of difficult-to-treat infections in a high-intensity medical care ward	4
A novel evidence-based algorithm to predict thromboembolism in patients with COVID-19: preliminary data from a single-center cohort	4
Role of available COVID-19 vaccines in reducing deaths and perspective for next generation vaccines and therapies to counter emerging viral variants: an update	4
The effect and mechansim of β-arrestins in the regulation of microglia polarization in the pathogenesis of Parkinson's disease	4
Supplementation with Pycnogenol® relieves symptoms of chronic inflammatory diseases with a significant vasculitis component: a pilot registry study	4
Effect of hierarchical nursing model on complications of hemodialysis patients in ICU and its effect evaluation	4
Clinical efficacy and application value of comprehensive internal fixation surgery for complex ankle fracture patients	4
Pollution and health: the role of healthy lifestyle	3
The role and prognostic value of human peripheral blood interleukin-27, C-reactive protein, and serum amyloid a in inflammatory response of sepsis	3
Analysis and construction of differential protein expression correlation in atrial tissue of atrial fibrillation rats using iTRAQ technology	3
Efficacy of compound Xueshuantong capsule combined with citicoline in the treatment of glaucoma optic nerve atrophy	3
Comparison of transvaginal and transumbilical single-hole laparoscopy in the operation of uterine leiomyoma	3
Regular physical activity: a major component of isolated systolic hypertension in the young	3
Non-alcoholic fatty liver disease is not independently associated with Helicobacter pylori in a central European screening cohort	3
Pharmacological mechanisms underlying the androgen-reducing effects of Shaoyao Gancao decoction determined by network pharmacology and molecular docking	3
Application research of nursing model assisted by doctors and nurses in postoperative rehabilitation nursing of orthopedic patients	3
Clinical efficacy of Haiao prosthodontic membrane guided bone regeneration and its effect on bone mineral density	3
Budenoside aqueous nasal spray: an updated reappraisal in rhinitis management	3
Application of psychological nursing combined with exercise therapy in nursing of gestational diabetes mellitus	3
Constructing a needs-based collaborative care model for preterm infants and their families	3
The relationship between PTCHD1 expression and epileptic activity	3
Effect of continuous nursing on life comfort of patients with advanced non-small cell lung cancer after discharge	3
Quercetin ameliorates renal tubulointerstitial transformation and renal fibrosis by regulating NLRP3 in obstructive nephropathy	3
An umbrella review encompassing 42 systematic reviews on medical applications of ChatGPT	3
Evaluation of tolerability and major factors affecting the adherence to probiotic therapy in patients with irritable bowel syndrome: a prospective, observational, real-life study	3
Current progression in establishment and application of three-dimensional printing in urology	3
Comparative study of 3.0T magnetic resonance imaging and multislice spiral CT in the diagnosis of gastric cancer	3
A modified double-incision extracapsular cataract extraction combined with intraocular lens implantation in a senile cataract patient with low corneal endothelial cell density	3
Zercepac® plus capecitabine for intracranial lesions in a patient with HER2-positive converted from triple-negative breast cancer	3
Prognostic role of KL-6 in lymphangioleiomyomatosis patients	3
The anomalous origin of the left coronary artery from the pulmonary artery in adults	3
Treatment strategies for advanced spontaneous esophageal rupture	3
Effects of MiR-27a on proliferation and apoptosis of breast cancer cells by targeting KRAS	3
Postoperative psychological stress and expression of stress-related factors HSP70 and IFN-γ in patients with early lung cancer	3
Mechanism of mPEGS and FGF2 in miR-574-5p regulating pemetrexed resistance of lung adenocarcinoma in nude mice	3
The effect of targeted psychological nursing intervention on postoperative pain and quality of life in patients with radical mastectomy	3
The value of combined dynamic detection of coagulation and fibrinolytic factor in diagnosis and treatment of deep vein thrombosis after hip fracture operation in the elderly	3
Isolated systolic hypertension in the young: a heterogeneous condition	3
Noninvasive tools for the assessment of fibrosis in metabolic dysfunction-associated steatotic liver disease	3
Analysis of microsatellite instability in Korean patients with pancreatic cancer	3
Clinical effect of Guizhi Fuling Pill combined with metformin on chronic pelvic inflammatory disease and its influence on inflammatory reaction in rats	3
Health education, patients, and caregivers	3
The experimental promise and clinical reality of myocardial conditioning for prevention of myocardial ischemia and reperfusion injury: an umbrella review of systematic reviews	3
Correlation between PET/CT findings and pathological features of mediastinal lymph nodes in non-small cell lung cancer	3
Effect of targeted nursing intervention on negative mental status and quality of life of elderly patients with coronary heart disease	3
Obstructive sleep apnea and smoke: descriptive-observational study in the Republic of San Marino	3
Correction to: Sublingual sufentanil tablet system for postoperative analgesia after gynecological surgery	3
TRIM33/RORγt signaling pathway promoted immune inflammation in mice of AE through miR-338-3p/Circ RNA 001076	3
Primary retroperitoneal renal cell carcinoma associated with transcription EB gene fusion	3
Evaluation and treatment of pelvic organ prolapse	3
Therapeutic approaches in the management of chronic kidney disease: the past, the present, and the future	3
Chronic hepatitis B infection and diabetes mellitus: a double liver trouble?	3
Lights of cholangioscopy by SpyGlass™ DS in detecting indeterminate biliary strictures: is it time to definitely discard the traditional endoscopic retrograde cholangiopancreatography (ERCP)-based sam	3
Nutrition program, physical activity and gut microbiota modulation: a randomized controlled trial to promote a healthy lifestyle in students with vitamin D3 deficiency	3