Life Sciences

Article	Citations
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	271
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	259
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	204
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	179
A detailed insight into macrophages' role in shaping lung carcinogenesis	117
Editorial Board	116
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	111
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	109
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	107
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	107
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	91
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	87
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	87
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	85
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	84
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	84
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	84
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	84
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	82
Fluid shear stress facilitates prostate cancer metastasis through Piezo1-Src-YAP axis	82
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	82
Encapsulated mesenchymal stem cell-derived exosomes promote optic nerve regeneration and functional recovery in a mouse model of optic nerve crush injury	81
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	81
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	81
The N6-methyladenosine modification in pathologic angiogenesis	80

The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	80
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	76
Molecular insights into the causal role of TG/IDL in rheumatoid arthritis: Integrating Mendelian randomization and single-cell RNA sequencing	75
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	73
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	73
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	73
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	72
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer	72
Downregulation of CDC42 contributes to pulmonary vascular endothelial hyperpermeability and acute lung injury induced by seawater drowning	70
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	70
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	68
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	67
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	67
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	66
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	66
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome	65
Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends	65
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	64
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	64
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	63
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	61
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	61
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-	60
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	60
HDAC11 deficiency improves muscle phenotype in a Duchenne muscular dystrophy murine model by reducing inflammation and fibrosis	59
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	59
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	59
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	59
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	58
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	58
Screening strategy using a filamentous fungus model to repurpose drugs for mitochondrial complex I deficiencies	57
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	57
CpG-mediated TLR9 signaling pathway enhances the efficacy of the OprF/PcrV DNA vaccine with cGAS-STING-activating properties	57
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	56
Tuberous sclerosis complex 2 deficiency in cardiomyocytes exacerbates cardiac remodeling in diabetic mice	56
Role of left and right vagus nerves in linking peripheral adrenergic signals to contextual fear memory	55
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	55
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	55
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	54
Retraction notice to “Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone” [Life Sci. 88 (2011) 619–627]	54
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	53
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury	53
Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	53
Sinomenine ameliorates myocardial ischemia/reperfusion injury by inhibiting mitochondrial oxidative stress-mediated PANoptosis and ferroptosis via α7nAChR	53
Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis	53
Hesperidin attenuates hepatic lipid accumulation in mice fed high-fat diet and oleic acid induced HepG2 via AMPK activation	51
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	51
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	51
Mitochondrial transfer in the progression and treatment of cardiac disease	51
Copper homeostasis and cuproptosis in mitochondria	51

Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway	50
Identification of specific gut microbes and their therapeutic potential in ameliorating systemic lupus erythematosus in a mouse model	50
Ser235 phosphorylation of hepatitis C virus NS5A is required for NS5A dimerization and drug resistance	49
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7	49
Biliverdin alleviates cerebral ischemia-reperfusion injury by inhibiting autophagy via the lncRNA TUG1 /miR-204-5p/P4HB axis	48
Editorial Board	48
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway	47
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice	47
The potential of sertoli cells (SCs) derived exosomes and its therapeutic efficacy in male reproductive disorders	47
Corrigendum to “Hydroxyl containing benzo[b]thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle” [Life Sci. 298 (2022	46
N-acetylcysteine alleviates oxidative stress and apoptosis and prevents skeletal muscle atrophy in type 1 diabetes mellitus through the NRF2/HO-1 pathway	46
Modulation of cardiac voltage-activated K+ currents by glypican 1 heparan sulfate proteoglycan	46
Glucocorticoid reduces mortality in LPS-induced sepsis mouse model by inhibiting JAK1/STAT3-mediated inflammatory response and restoring tricarboxylic acid cycle	46
Probenecid induces the recovery of renal ischemia/reperfusion injury via the blockade of Pannexin 1/P2X7 receptor axis	46
Altered sperm fate in the reproductive tract milieu due to oxidative stress leads to sub-fertility in type 1 diabetes females: A Drosophila-based study	45
Exploring the gut-lung-brain axis: Focus on endothelial dysfunction, impaired bioenergetics, and strategies to mitigate lung and cognitive disorders	45
Mollugin activates GLP-1R to improve cognitive dysfunction in type 2 diabetic mice	45
Pain in rheumatoid arthritis: Emerging role of high mobility group box 1 protein-HMGB1	44
The physical exercise-induced oxidative/inflammatory response in peripheral blood mononuclear cells: Signaling cellular energetic stress situations	44
Exploring the therapeutic potential of tetrahydrobiopterin for heart failure with preserved ejection fraction: A path forward	43
Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia	43
Efficacy of lipid nanoparticles-based vaccine to protect against vulvovaginal candidiasis (VVC): Implications for women's reproductive health	43
Fecal microbiota transplantation for diseases: Therapeutic potential, methodology, risk management in clinical practice	43
Tumor-associated macrophages: Potential target of natural compounds for management of breast cancer	43
Liraglutide attenuates doxorubicin-induced cardiomyocyte ferroptosis via DHHC7-mediated STAT3 palmitoylation	43
PXDNL activates the motility of urothelial bladder carcinoma cells through the Wnt/β-catenin pathway and has a prognostic value	43
Gastric dilation following vertical sleeve gastrectomy reflects adaptive stem cell-driven regeneration without association with weight regain or increased cancer risk	42
Update on the transdifferentiation of pancreatic cells into functional beta cells for treating diabetes	42
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models	42
5/6 nephrectomy affects enteric glial cells and promotes impaired antioxidant defense in the colonic neuromuscular layer	42
The role of RAB12 in inhibiting osteogenic differentiation and driving metabolic dysregulation in osteoporosis	42
Therapeutic applications of mesenchymal/medicinal stem/signaling cells preconditioned with external factors: Are there more efficient approaches to utilize their regenerative potential?	41
IKKβ inhibits cognitive memory and adult hippocampal neurogenesis by modulating the β-catenin pathway	41
The IRβ/HCF-1/ChREBP axis: A new paradigm in insulin-regulated hepatic lipogenesis	41
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae	41
Aerobic exercise training attenuates ischemia-reperfusion injury in mice by decreasing the methylation level of METTL3-associated m6A RNA in cardiomyocytes	41
Gut microbiota and late-life depression: from mechanistic insights to clinical rehabilitation	41
Simvastatin reduces plasma membrane caveolae and caveolin-1 in uterine leiomyomas	41
Retraction notice to “miR-98-5p inhibits gastric cancer cell stemness and chemoresistance by targeting branched-chain aminotransferases 1” [Life Sci. 276 (2021) 119405]	40
Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood	40
Corrigendum to “Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice” [Life Sci. 239 (2019) 116878]	40
Corrigendum to “Exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating APJ/STAT3 in mice with stroke” [Life Sci. 332 (2023) 122041]	40
Role of sulforaphane in endoplasmic reticulum homeostasis through regulation of the antioxidant response	40
Retraction notice to “Sevoflurane improves nerve regeneration and repair of neurological deficit in brain damage rats via microRNA-490-5p/CDK1 axis” [Life Sci. 271 (2021) 119111]	40
Unveiling OSCP as the potential therapeutic target for mitochondrial dysfunction-related diseases	40
Nerolidol attenuates dehydroepiandrosterone-induced polycystic ovary syndrome in rats by regulating oxidative stress and decreasing apoptosis	40
Modulating intestinal viruses: A potential avenue for improving metabolic diseases with unresolved challenges	39
Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders	39
A new view on functions of the lysine demalonylase activity of SIRT5	39
Covid-19 a triggering factor of autoimmune and multi-inflammatory diseases	39
An improved mouse model of sepsis based on intraperitoneal injections of the enriched culture of cecum slurry	39
Oxidative stress imposed in vivo anticancer therapeutic efficacy of novel imidazole-based oxidovanadium (IV) complex in solid tumor	38
Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management	38
AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage	38
The influence of microenvironment stiffness on endothelial cell fate: Implication for occurrence and progression of atherosclerosis	38
Interrogating Salmonella Typhi biofilm formation and dynamics to understand antimicrobial resistance	38
Ursodeoxycholic acid alleviates atopic dermatitis-associated inflammatory responses in HaCaT and RBL-2H3 cells and DNCB/DFE-treated mice	38
Understanding the physiological mechanisms and therapeutic targets of diseases: Lipidomics strategies	38
PPARγ agonist alleviates sepsis-related liver injury by modulating M1/M2 macrophage polarization via the PPARγ/IκBα/NF-κB pathway	38
Tauroursodeoxycholate prevents estradiol 17β-d-glucuronide-induced cholestasis and endocytosis of canalicular transporters by switching off pro-cholestatic signaling pathways	37
Cancer cell's internal and external warriors: Autophagosomes and exosomes	37
Comprehensive insights into the multifaceted roles of the transient receptor potential vanilloid 1 channel in the digestive system	37
Transcriptional and post-translational mechanisms of ECM remodeling in rotator cuff tendons under hyperlipidemic conditions	37
The hepatoprotective effects of n3-polyunsaturated fatty acids against non-alcoholic fatty liver disease in diabetic rats through the FOXO1/PPARα/GABARAPL1 signalling pathway	37
Low dose Taxol ameliorated renal fibrosis in mice with diabetic kidney disease by downregulation of HIPK2	37
The potential protective effects of estradiol and 2-methoxyestradiol in ischemia reperfusion-induced kidney injury in ovariectomized female rats	37
Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation	37
Pathophysiologic effects of waterpipe (shisha) smoke inhalation on liver morphology and function in mice	37
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction	37
CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation	37
Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation	36
Moderate intestinal immunopathology after acute oral infection with Toxoplasma gondii oocysts is associated with expressive levels of serotonin	36
New role of obscure acylation modifications in cardiovascular diseases: what's beyond?	36
Catechins prevent obesity-induced kidney damage by modulating PPARγ/CD36 pathway and gut-kidney axis in rats	36
Selective APC-targeting of a novel Fc-fusion multi-immunodominant recombinant protein (tTax-tEnv:mFcγ2a) for HTLV-1 vaccine development	36
Effects of apelin on age-associated neovascularization impairment in peripheral artery disease	36
Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro	35
Pulmonary neuroendocrine cell as a therapeutic strategy in pulmonary hypertension: Great expectations or Bleak House?	35
CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the ErbB3/STAT3 signaling pathway	35
Maladaptive plasticity induced by morphine is mediated by hippocampal astrocytic Connexin-43	35

Anti-apoptotic and neurogenic properties in the hippocampus as possible mechanisms for learning and memory improving impacts of vitamin D in hypothyroid rats during the growth period	35
Autophagy regulation in ovarian cancer chemoresistance: Molecular mechanisms and emerging frontiers	35
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction	35
Renal cell carcinoma management: A step to nano-chemoprevention	35
The Rab GTPase in the heart: Pivotal roles in development and disease	35
The role of viruses in cancer progression versus cancer treatment: A dual paradigm	35
Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway	35
Contributions of the gut microbiota to Gulf War Illness susceptibility: Findings from a mouse model	34
Depot- and diabetes-specific differences in norepinephrine-mediated adipose tissue angiogenesis, vascular tone, collagen deposition and morphology in obesity	34
Editorial Board	34
Nanocellulose dysregulated glucose homeostasis in female mice on a Western diet: The role of gut microbiome	34
Altered GnRH neuron-glia networks close to interface of polycystic ovary syndrome: Molecular mechanism and clinical perspectives	34
Editorial Board	34
Activation of CB1R alleviates autism spectrum disorder-like behavior and synaptic impairments	34
Oxidative stress in animal models of obesity caused by hypercaloric diets: A systematic review	34
Editorial Board	34
Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease	34
RNF8-mediated multi-ubiquitination of MCM7: Linking disassembly of the CMG helicase with DNA damage response in human cells	33
Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippoca	33
SIRT6 inhibits hypoxia-induced pulmonary arterial smooth muscle cells proliferation via HIF-1α/PDK4 signaling	33
LETM1 deacetylation attenuates calcium overload–mediated mitochondrial injury and protects the intestine from ischemia/reperfusion damage	33
The role of organic anion transport peptides in cyclophosphamide-induced hepatotoxicity in high-fat diet mice	33
Sugar-sweetened beverage consumption retarded weight gain but not induced depression and anxiety-like behaviors in mice	33
Effects of high levels of androgens on oocyte maturation and potential regulatory role of retinoic acid	33
Rodent models for dry eye syndrome: Standardization using benzalkonium chloride and scopolamine hydrobromide	33
Nickel chloride promotes lung cancer invasion and metastasis by up-regulating the expression of E3 ubiquitin ligase TRIM31 through the IL-6/STAT3 signaling axis	33
Necroptosis modulation by cisplatin and sunitinib in hepatocellular carcinoma cell line	33
Role of melatonin in mitigation of insulin resistance and ensuing diabetic cardiomyopathy	33
Unraveling the signaling mechanisms behind Histoplasma capsulatum-induced neutrophil NETosis	32
Levistolide A ameliorates fibrosis in chronic kidney disease via modulating multitarget actions in vitro and in vivo	32
Corrigendum to “Protective effects of Nrf2 against sepsis-induced hepatic injury” [Life Sci. 282 (2021) 119807]	32
The prevalence of drug–drug interactions in cancer therapy and the clinical outcomes	32
Corrigendum to “In vivo biochemical evaluations of some β-lactam group antibiotics on glutathione reductase and glutathione S-transferase enzyme activities” [Life Sci., volume 231 (2019) 116572]	32
Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression	32
Secretoglobin 3A2 peptides have therapeutic potential for allergic airway inflammation	32
Chronic alcohol feeding alters lymph and plasma proteome in a rodent model	32
Cancer immunotherapy resistance: The impact of microbiome-derived short-chain fatty acids and other emerging metabolites	32
Effects of IGF-1 receptor inactivation in tyrosine hydroxylase cells on body growth and growth hormone secretion	32
Regucalcin downregulation in human cancer	32
Corrigendum to “NEAT1: Culprit lncRNA linking PIG C, MSLN, and CD80 in triple-negative breast cancer” [Life Sci., volume 299 (2022) 120523]	32
Alpha-lipoic acid protects against aortic aneurysm and dissection by improving vascular smooth muscle cell function	32
MicroRNA-217 modulates pancreatic cancer progression via targeting ATAD2	31
Genome-wide screening and identification of potential kinases involved in endoplasmic reticulum stress responses	31
PSME2 promotes malignant progression through autophagy modulation via IL-6/STAT3 signaling pathway in esophageal squamous cell carcinoma	31
The underlying mechanism and therapeutic potential of IFNs in viral-associated cancers	31
Thyroid hormone ameliorates ursodeoxycholic acid-induced heart damage in zebrafish embryos	31
Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation	31
Editorial Board	31
Challenges in clinical practice, biological mechanism and prospects of physical ablation therapy for COPD	31
Organic vs. inorganic nitrates: Metabolic and vascular outcomes in STZ-induced diabetes in mice	31
Cryopreserved clinical-grade human embryonic stem cell-derived dopaminergic progenitors function in Parkinson's disease models	31
Antineoplastic agents in chemotherapy facilitating tumor growth and angiogenesis in the interval administrations	31
Organ-restricted delivery through stimuli-responsive nanocarriers for lung cancer therapy	31
Untargeted metabolomics profiling of 24-h ultramarathon runners: new insights into the biochemical alterations and the identification of performance biomarkers	30
Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage	30
Distinct roles for orexin-1 and orexin-2 receptors in the dentate gyrus of the hippocampus in the methamphetamine-seeking behavior in the rats	30
FoxM1 promotes the proliferation of cervical adenocarcinoma cells through transcriptional activation of FAM83D	30
Subacute administration of cilostazol modulates PLC-γ/PKC-α/p38/NF-kB pathway and plays vascular protective effects through eNOS activation in early stages of atherosclerosis development	30
Hyperoxic exposure alters intracellular bioenergetics distribution in human pulmonary cells	30
Assessment of mitochondrial dysfunction and implications in cardiovascular disorders	30
LncRNA MEG3 regulates the interplay between Th17 and Treg cells in Behçet's disease and systemic lupus erythematosus	30
Dysregulation of immune and metabolism pathways in maternal immune activation induces an increased risk of autism spectrum disorders	30
Lunasin ameliorates glucose utilization in C2C12 myotubes and metabolites profile in diet-induced obese mice benefiting metabolic disorders	30
Probiotics and the reduction of SARS-CoV-2 infection through regulation of host cell calcium dynamics	30
Identification of distinct immune infiltration and potential biomarkers in patients with liver ischemia-reperfusion injury	30
The association between type 1 diabetes and exercise/physical activity and prolongation of the honeymoon phase in patients	30
Cigarette smoke-induced galectin-3 as a diagnostic biomarker and therapeutic target in lung tissue remodeling	30
Chitosan based nanoformulation expressing miR-155 as a promising adjuvant to enhance Th1-biased immune responses	30
Synovial microenvironment in temporomandibular joint osteoarthritis: crosstalk with chondrocytes and potential therapeutic targets	30
Circ_0002638 drives squamous cell lung cancer (LUSC) progression and chemotherapy resistance by inhibiting ferroptosis via SENP1-mediated deSUMOylation of ACSL4	30
N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1α/glycolysis/ASIC1a pathway	30
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain	30
H-ras-targeted genetic therapy remarkably surpassed docetaxel treatment in inhibiting chemically induced hepatic tumors in rats	30
Enhanced eNOS/nitric oxide production by nebivolol interferes with TGF-β1/Smad3 signaling and collagen I deposition in the kidney after prolonged tacrolimus administration	30
New insights on the impact of gut microbiota on premenstrual disorders. Will probiotics solve this mystery?	29
Vulnerability and resilience to cardiovascular and neuroendocrine effects of stress in adult rats with historical of chronic stress during adolescence	29
Neuronal PAC1 deletion impairs structural plasticity	29
Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling	29
FAM96A suppresses epithelial–mesenchymal transition and tumor metastasis by inhibiting TGFβ1 signals	29
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation	29
Potential therapeutic and diagnostic approaches of exosomes in multiple sclerosis pathophysiology	29
Plasma exosomes from patients with acute myocardial infarction alleviate myocardial injury by inhibiting ferroptosis through miR-26b-5p/SLC7A11 axis	29
Electroacupuncture for weight loss by regulating microglial polarization in the arcuate nucleus of the hypothalamus	29
Fgf21-Dubosiella axis mediates the protective effects of exercise against NAFLD development	29
ZD-2, a novel DPP4 inhibitor, protects islet β-cell and improves glycemic control in high-fat-diet-induced obese mice	29
Activation of megakaryocytic leukemia 1 in endothelial cells contributes to diabetic retinopathy in mice	29
The effect of mesenchymal stem cell-derived supernatant nasal administration on lung inflammation and immune response in BCG-vaccinated BALB/c mice	29
S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function	29
Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer	29
Cold and longevity: Can cold exposure counteract aging?	29
Gastrointestinal manifestations of long COVID	29
Targeting DNA methylation in diabetic kidney disease: A new perspective	29
Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis	29
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction by inhibiting pyroptosis via NLRP3/Caspase1/Gasdermin D signaling axis	29
Phospholipase D2 drives cellular lipotoxicity and tissue inflammation in alcohol-associated liver disease	28