Life Sciences

Article	Citations
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	308
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	272
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	221
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	204
A detailed insight into macrophages' role in shaping lung carcinogenesis	138
Editorial Board	137
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	127
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	123
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	120
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	117
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	107
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	103
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	100
The N6-methyladenosine modification in pathologic angiogenesis	99
HDAC11 deficiency improves muscle phenotype in a Duchenne muscular dystrophy murine model by reducing inflammation and fibrosis	95
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	93
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	92
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	91
Identification of specific gut microbes and their therapeutic potential in ameliorating systemic lupus erythematosus in a mouse model	89
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	87
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	86
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	86
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	85
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	83
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	82

Screening strategy using a filamentous fungus model to repurpose drugs for mitochondrial complex I deficiencies	82
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	82
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	82
Role of left and right vagus nerves in linking peripheral adrenergic signals to contextual fear memory	81
Tuberous sclerosis complex 2 deficiency in cardiomyocytes exacerbates cardiac remodeling in diabetic mice	81
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	80
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	77
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	76
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7	75
Downregulation of CDC42 contributes to pulmonary vascular endothelial hyperpermeability and acute lung injury induced by seawater drowning	75
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	73
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	72
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	71
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	71
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	70
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	69
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	68
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	67
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	67
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	67
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	66
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	66
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	64
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	64
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	64
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	64
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	63
Salvianolic acid A inhibits tumor cell proliferation and induces chromosomal abnormalities by blocking the citrullinating enzyme PADs	63
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	59
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	59
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	59
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-	59
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	58
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	58
High-intensity interval training attenuates post-myocardial infarction remodeling and ITGAM-mediated M4 macrophage polarization	57
Fluid shear stress facilitates prostate cancer metastasis through Piezo1-Src-YAP axis	57
Copper homeostasis and cuproptosis in mitochondria	57
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	56
Targeting P2X purinergic receptors with suramin alleviates rotenone-induced Parkinson's-like pathology via modulation of mitophagy and NLRP3-pyroptosis: Comparison with metformin	55
Retraction notice to “Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone” [Life Sci. 88 (2011) 619–627]	54
Mitochondrial transfer in the progression and treatment of cardiac disease	54
Sinomenine ameliorates myocardial ischemia/reperfusion injury by inhibiting mitochondrial oxidative stress-mediated PANoptosis and ferroptosis via α7nAChR	53
CpG-mediated TLR9 signaling pathway enhances the efficacy of the OprF/PcrV DNA vaccine with cGAS-STING-activating properties	53
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury	52
Encapsulated mesenchymal stem cell-derived exosomes promote optic nerve regeneration and functional recovery in a mouse model of optic nerve crush injury	52
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	52
Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway	51
Molecular insights into the causal role of TG/IDL in rheumatoid arthritis: Integrating Mendelian randomization and single-cell RNA sequencing	51
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	51
Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis	51

Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	51
Modulating intestinal viruses: A potential avenue for improving metabolic diseases with unresolved challenges	50
AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage	50
Biliverdin alleviates cerebral ischemia-reperfusion injury by inhibiting autophagy via the lncRNA TUG1 /miR-204-5p/P4HB axis	50
Altered sperm fate in the reproductive tract milieu due to oxidative stress leads to sub-fertility in type 1 diabetes females: A Drosophila-based study	50
Ser235 phosphorylation of hepatitis C virus NS5A is required for NS5A dimerization and drug resistance	50
Unveiling OSCP as the potential therapeutic target for mitochondrial dysfunction-related diseases	49
CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation	49
The hepatoprotective effects of n3-polyunsaturated fatty acids against non-alcoholic fatty liver disease in diabetic rats through the FOXO1/PPARα/GABARAPL1 signalling pathway	49
Exploring the therapeutic potential of tetrahydrobiopterin for heart failure with preserved ejection fraction: A path forward	49
Tauroursodeoxycholate prevents estradiol 17β-d-glucuronide-induced cholestasis and endocytosis of canalicular transporters by switching off pro-cholestatic signaling pathways	49
Pathophysiologic effects of waterpipe (shisha) smoke inhalation on liver morphology and function in mice	48
Activation of CB1R alleviates autism spectrum disorder-like behavior and synaptic impairments	48
Contributions of the gut microbiota to Gulf War Illness susceptibility: Findings from a mouse model	48
Nanocellulose dysregulated glucose homeostasis in female mice on a Western diet: The role of gut microbiome	48
The IRβ/HCF-1/ChREBP axis: A new paradigm in insulin-regulated hepatic lipogenesis	48
Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease	47
Depot- and diabetes-specific differences in norepinephrine-mediated adipose tissue angiogenesis, vascular tone, collagen deposition and morphology in obesity	47
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway	47
Modulation of cardiac voltage-activated K+ currents by glypican 1 heparan sulfate proteoglycan	46
Maladaptive plasticity induced by morphine is mediated by hippocampal astrocytic Connexin-43	46
Selective APC-targeting of a novel Fc-fusion multi-immunodominant recombinant protein (tTax-tEnv:mFcγ2a) for HTLV-1 vaccine development	45
The Rab GTPase in the heart: Pivotal roles in development and disease	45
Effects of apelin on age-associated neovascularization impairment in peripheral artery disease	45
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae	45
The role of viruses in cancer progression versus cancer treatment: A dual paradigm	44
Pulmonary neuroendocrine cell as a therapeutic strategy in pulmonary hypertension: Great expectations or Bleak House?	44
Corrigendum to “Hydroxyl containing benzo[b]thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle” [Life Sci. 298 (2022	44
Probenecid induces the recovery of renal ischemia/reperfusion injury via the blockade of Pannexin 1/P2X7 receptor axis	44
Retraction notice to “miR-98-5p inhibits gastric cancer cell stemness and chemoresistance by targeting branched-chain aminotransferases 1” [Life Sci. 276 (2021) 119405]	43
Comprehensive insights into the multifaceted roles of the transient receptor potential vanilloid 1 channel in the digestive system	43
Gastric dilation following vertical sleeve gastrectomy reflects adaptive stem cell-driven regeneration without association with weight regain or increased cancer risk	43
Retraction notice to “Sevoflurane improves nerve regeneration and repair of neurological deficit in brain damage rats via microRNA-490-5p/CDK1 axis” [Life Sci. 271 (2021) 119111]	43
Transcriptional and post-translational mechanisms of ECM remodeling in rotator cuff tendons under hyperlipidemic conditions	43
Corrigendum to “Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice” [Life Sci. 239 (2019) 116878]	43
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models	43
Understanding the physiological mechanisms and therapeutic targets of diseases: Lipidomics strategies	42
Oxidative stress in animal models of obesity caused by hypercaloric diets: A systematic review	42
Corrigendum to “Exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating APJ/STAT3 in mice with stroke” [Life Sci. 332 (2023) 122041]	42
Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro	42
Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation	42
The influence of microenvironment stiffness on endothelial cell fate: Implication for occurrence and progression of atherosclerosis	42
Altered GnRH neuron-glia networks close to interface of polycystic ovary syndrome: Molecular mechanism and clinical perspectives	42
Gut microbiota and late-life depression: from mechanistic insights to clinical rehabilitation	42
Aerobic exercise training attenuates ischemia-reperfusion injury in mice by decreasing the methylation level of METTL3-associated m6A RNA in cardiomyocytes	41
Fecal microbiota transplantation for diseases: Therapeutic potential, methodology, risk management in clinical practice	41
Thiamine pyrophosphate suppresses platelet activation by modulating PI3K-Akt and MAPK pathways: An integrated network pharmacology and experimental study	41
CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the ErbB3/STAT3 signaling pathway	41
Interrogating Salmonella Typhi biofilm formation and dynamics to understand antimicrobial resistance	41
Renal cell carcinoma management: A step to nano-chemoprevention	41
Mollugin activates GLP-1R to improve cognitive dysfunction in type 2 diabetic mice	41
Therapeutic applications of mesenchymal/medicinal stem/signaling cells preconditioned with external factors: Are there more efficient approaches to utilize their regenerative potential?	41
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction	41
Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation	40
Nerolidol attenuates dehydroepiandrosterone-induced polycystic ovary syndrome in rats by regulating oxidative stress and decreasing apoptosis	40
Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management	40
Efficacy of lipid nanoparticles-based vaccine to protect against vulvovaginal candidiasis (VVC): Implications for women's reproductive health	40
Covid-19 a triggering factor of autoimmune and multi-inflammatory diseases	40
Glucocorticoid reduces mortality in LPS-induced sepsis mouse model by inhibiting JAK1/STAT3-mediated inflammatory response and restoring tricarboxylic acid cycle	40
Simvastatin reduces plasma membrane caveolae and caveolin-1 in uterine leiomyomas	40
PXDNL activates the motility of urothelial bladder carcinoma cells through the Wnt/β-catenin pathway and has a prognostic value	40
Pain in rheumatoid arthritis: Emerging role of high mobility group box 1 protein-HMGB1	40
Catechins prevent obesity-induced kidney damage by modulating PPARγ/CD36 pathway and gut-kidney axis in rats	40
New role of obscure acylation modifications in cardiovascular diseases: what's beyond?	39
Liraglutide attenuates doxorubicin-induced cardiomyocyte ferroptosis via DHHC7-mediated STAT3 palmitoylation	39
A new view on functions of the lysine demalonylase activity of SIRT5	39
Exploring the gut-lung-brain axis: Focus on endothelial dysfunction, impaired bioenergetics, and strategies to mitigate lung and cognitive disorders	39
The role of RAB12 in inhibiting osteogenic differentiation and driving metabolic dysregulation in osteoporosis	39
Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders	39
An improved mouse model of sepsis based on intraperitoneal injections of the enriched culture of cecum slurry	38
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction	38
Moderate intestinal immunopathology after acute oral infection with Toxoplasma gondii oocysts is associated with expressive levels of serotonin	38
Anti-apoptotic and neurogenic properties in the hippocampus as possible mechanisms for learning and memory improving impacts of vitamin D in hypothyroid rats during the growth period	37
Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway	37
Autophagy regulation in ovarian cancer chemoresistance: Molecular mechanisms and emerging frontiers	37
Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood	37
Low dose Taxol ameliorated renal fibrosis in mice with diabetic kidney disease by downregulation of HIPK2	37
Update on the transdifferentiation of pancreatic cells into functional beta cells for treating diabetes	37
The potential of sertoli cells (SCs) derived exosomes and its therapeutic efficacy in male reproductive disorders	37
Ursodeoxycholic acid alleviates atopic dermatitis-associated inflammatory responses in HaCaT and RBL-2H3 cells and DNCB/DFE-treated mice	37

N-acetylcysteine alleviates oxidative stress and apoptosis and prevents skeletal muscle atrophy in type 1 diabetes mellitus through the NRF2/HO-1 pathway	36
Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia	36
Research progress on pathogenesis and treatment of febrile seizures	36
Genistein accelerates glucose catabolism via activation the GPER-mediated cAMP/PKA-AMPK signaling pathway in broiler chickens	36
Chronic intermittent hypoxia-induced H2S production promotes carotid body hyperactivity via the upregulation of Sp1 S-sulfhydration and angiotensin II receptor	36
IKKβ inhibits cognitive memory and adult hippocampal neurogenesis by modulating the β-catenin pathway	36
Editorial Board	36
Rodent models for dry eye syndrome: Standardization using benzalkonium chloride and scopolamine hydrobromide	36
Editorial Board	36
The physical exercise-induced oxidative/inflammatory response in peripheral blood mononuclear cells: Signaling cellular energetic stress situations	36
PPARγ agonist alleviates sepsis-related liver injury by modulating M1/M2 macrophage polarization via the PPARγ/IκBα/NF-κB pathway	36
The association between type 1 diabetes and exercise/physical activity and prolongation of the honeymoon phase in patients	36
The underlying mechanism and therapeutic potential of IFNs in viral-associated cancers	36
Regucalcin downregulation in human cancer	35
Proteotoxicity and tubular epithelial cell fate in acute kidney injury: Molecular insights and treatment strategies	35
Calycosin attenuates renal fibrosis by modulating lipid metabolism via the PCK1/TWIST1/CPT1α axis	35
Semaglutide alleviates the pancreatic β cell function via the METTL14 signaling and modulating gut microbiota in type 2 diabetes mellitus mice	35
Potential therapeutic and diagnostic approaches of exosomes in multiple sclerosis pathophysiology	35
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction by inhibiting pyroptosis via NLRP3/Caspase1/Gasdermin D signaling axis	35
Hyperoxic exposure alters intracellular bioenergetics distribution in human pulmonary cells	35
Angiopoietin-2-mediated integrin α5β1 and FAK signaling contributes to pulmonary arterial hypertension pathogenesis	35
WTAP-m6A-ALOX15 axis mediates dendritic cells-keratinocytes interaction involved in lipid metabolism disorders to drive atopic dermatitis	35
Cigarette smoke-induced galectin-3 as a diagnostic biomarker and therapeutic target in lung tissue remodeling	35
Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage	34
Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis	34
Alpha-lipoic acid protects against aortic aneurysm and dissection by improving vascular smooth muscle cell function	34
Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer	34
Sugar-sweetened beverage consumption retarded weight gain but not induced depression and anxiety-like behaviors in mice	34
Organic vs. inorganic nitrates: Metabolic and vascular outcomes in STZ-induced diabetes in mice	34
Response to the Letter to the editor regarding conflicting reports of opaganib efficacy against high-fat diet-induced obesity	34
Fgf21-Dubosiella axis mediates the protective effects of exercise against NAFLD development	34
Antibacterial activity and metabolomic analysis of linalool against bovine mastitis pathogen Streptococcus agalactiae	34
Neuronal PAC1 deletion impairs structural plasticity	34
Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation	34
Chronic alcohol feeding alters lymph and plasma proteome in a rodent model	34
Circ_0002638 drives squamous cell lung cancer (LUSC) progression and chemotherapy resistance by inhibiting ferroptosis via SENP1-mediated deSUMOylation of ACSL4	34
Inhibition of the FOXO1–ROCK1 axis mitigates cardiomyocyte injury under chronic hypoxia in Tetralogy of Fallot by maintaining mitochondrial quality control	34
Editorial Board	34
Probiotics and the reduction of SARS-CoV-2 infection through regulation of host cell calcium dynamics	33
FoxM1 promotes the proliferation of cervical adenocarcinoma cells through transcriptional activation of FAM83D	33
Genome-wide screening and identification of potential kinases involved in endoplasmic reticulum stress responses	33
Cryopreserved clinical-grade human embryonic stem cell-derived dopaminergic progenitors function in Parkinson's disease models	33
Thyroid hormone ameliorates ursodeoxycholic acid-induced heart damage in zebrafish embryos	33
Distinct roles for orexin-1 and orexin-2 receptors in the dentate gyrus of the hippocampus in the methamphetamine-seeking behavior in the rats	33
The prevalence of drug–drug interactions in cancer therapy and the clinical outcomes	33
PSME2 promotes malignant progression through autophagy modulation via IL-6/STAT3 signaling pathway in esophageal squamous cell carcinoma	33
Challenges in clinical practice, biological mechanism and prospects of physical ablation therapy for COPD	33
Secretoglobin 3A2 peptides have therapeutic potential for allergic airway inflammation	33
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain	33
Synovial microenvironment in temporomandibular joint osteoarthritis: crosstalk with chondrocytes and potential therapeutic targets	33
Effects of IGF-1 receptor inactivation in tyrosine hydroxylase cells on body growth and growth hormone secretion	33
Editorial Board	33
Lunasin ameliorates glucose utilization in C2C12 myotubes and metabolites profile in diet-induced obese mice benefiting metabolic disorders	33
The role of organic anion transport peptides in cyclophosphamide-induced hepatotoxicity in high-fat diet mice	33
LncRNA MEG3 regulates the interplay between Th17 and Treg cells in Behçet's disease and systemic lupus erythematosus	33
Effects of high levels of androgens on oocyte maturation and potential regulatory role of retinoic acid	32
Subacute administration of cilostazol modulates PLC-γ/PKC-α/p38/NF-kB pathway and plays vascular protective effects through eNOS activation in early stages of atherosclerosis development	32
LETM1 deacetylation attenuates calcium overload–mediated mitochondrial injury and protects the intestine from ischemia/reperfusion damage	32
Pre-hemodialysis exercise training improves systemic aerobic capacity and platelet bioenergetic efficiency in patients with end-stage renal disease	32
Nickel chloride promotes lung cancer invasion and metastasis by up-regulating the expression of E3 ubiquitin ligase TRIM31 through the IL-6/STAT3 signaling axis	32
SARS-CoV-2 infection and replication kinetics in different human cell types: The role of autophagy, cellular metabolism and ACE2 expression	32
Electroacupuncture for weight loss by regulating microglial polarization in the arcuate nucleus of the hypothalamus	32
Corrigendum to “In vivo biochemical evaluations of some β-lactam group antibiotics on glutathione reductase and glutathione S-transferase enzyme activities” [Life Sci., volume 231 (2019) 116572]	32
H-ras-targeted genetic therapy remarkably surpassed docetaxel treatment in inhibiting chemically induced hepatic tumors in rats	32
Activation of megakaryocytic leukemia 1 in endothelial cells contributes to diabetic retinopathy in mice	32
Cold and longevity: Can cold exposure counteract aging?	32
Editorial Board	32
Dysregulation of immune and metabolism pathways in maternal immune activation induces an increased risk of autism spectrum disorders	32
Corrigendum to “Protective effects of Nrf2 against sepsis-induced hepatic injury” [Life Sci. 282 (2021) 119807]	32
Corrigendum to “NEAT1: Culprit lncRNA linking PIG C, MSLN, and CD80 in triple-negative breast cancer” [Life Sci., volume 299 (2022) 120523]	32
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation	32
The effect of mesenchymal stem cell-derived supernatant nasal administration on lung inflammation and immune response in BCG-vaccinated BALB/c mice	32
Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling	32
Gastrointestinal manifestations of long COVID	32
Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippoca	32
Plasma exosomes from patients with acute myocardial infarction alleviate myocardial injury by inhibiting ferroptosis through miR-26b-5p/SLC7A11 axis	31
Enhanced eNOS/nitric oxide production by nebivolol interferes with TGF-β1/Smad3 signaling and collagen I deposition in the kidney after prolonged tacrolimus administration	31
Unraveling the signaling mechanisms behind Histoplasma capsulatum-induced neutrophil NETosis	31
SIRT6 inhibits hypoxia-induced pulmonary arterial smooth muscle cells proliferation via HIF-1α/PDK4 signaling	31
Organ-restricted delivery through stimuli-responsive nanocarriers for lung cancer therapy	31
N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1α/glycolysis/ASIC1a pathway	31
Antineoplastic agents in chemotherapy facilitating tumor growth and angiogenesis in the interval administrations	31
Gut microbiota in obesity and related complications: Unveiling the complex interplay	31
RNF8-mediated multi-ubiquitination of MCM7: Linking disassembly of the CMG helicase with DNA damage response in human cells	31
Maternal obesity impacts fetal liver androgen signalling in a sex-specific manner	31
Vulnerability and resilience to cardiovascular and neuroendocrine effects of stress in adult rats with historical of chronic stress during adolescence	31
A direct estrogenic involvement in the expression of human hypocretin	31
Assessment of mitochondrial dysfunction and implications in cardiovascular disorders	31
Targeting DNA methylation in diabetic kidney disease: A new perspective	31
Diamine oxidase acts as a novel risk factor in abnormal inflammation via mediating “cytosolic ROS-autophagy-IFN-γ” axis in NK cells	30
Retraction notice to “Overexpression of GRIM-19 accelerates radiation-induced osteosarcoma cells apoptosis by p53 stabilization” [Life Sci. 208 (2018) 208, 232–238]	30
Retraction notice to “Silencing STAT3 enhances sensitivity of cancer cells to doxorubicin and inhibits tumor progression” [Life Sci. 275 (2021) 119369]	30
Corrigendum to “Zebrafish mutants in egln1 display a hypoxic response and develop polycythemia” [Life Sci. 344 (2024) 122564]	30
circCNN2 drives endometrial cancer progression through ALKBH5/YTHDF2-mediated m6A regulation and miR-615-5p sponging	30
Corrigendum to “Modulation of autophagy and transient receptor potential vanilloid 4 channels by montelukast in a rat model of hemorrhagic cystitis” [Life Sci. 278 (2021) 119507]	30